🦟 D. melanogaster Batch 01: Development & Genetics

Programming Framework Analysis - 8 Eukaryotic Processes

🦟 Development & Genetics Systems

Batch Overview: This batch contains 8 fundamental D. melanogaster processes responsible for development and genetics. These processes represent the core computational systems that enable this model organism to develop from embryo to adult, exhibit complex behaviors, and maintain genetic integrity.

Each process demonstrates sophisticated biological programming with developmental pathways, genetic regulation, neural circuits, and behavioral responses.

1. Embryonic Patterning

Detailed analysis of D. melanogaster Embryonic Patterning using the Programming Framework, revealing computational logic and regulatory patterns for early development.

graph TD %% Patterning Components A[Maternal Factors] --> B[Anterior-Posterior Axis] C[Dorsal-Ventral Axis] --> D[Polarity Establishment] E[Gap Genes] --> F[Segment Polarity] G[Pair-Rule Genes] --> H[Pattern Formation] %% Maternal Control B --> I[Bicoid mRNA] I --> J[Nanos mRNA] J --> K[Protein Gradients] %% Axis Formation D --> L[Toll Signaling] L --> M[Dorsal Protein] M --> N[D-V Patterning] %% Gap Gene Expression F --> O[Giant Expression] O --> P[Krüppel Expression] P --> Q[Segment Boundaries] %% Integration K --> R[Patterning Program] N --> R Q --> R H --> R R --> S[Embryonic Pattern] %% Styling - Programming Framework Colors style A fill:#ff6b6b,color:#fff style C fill:#ff6b6b,color:#fff style E fill:#ff6b6b,color:#fff style G fill:#ff6b6b,color:#fff style B fill:#ffd43b,color:#000 style D fill:#ffd43b,color:#000 style F fill:#ffd43b,color:#000 style H fill:#ffd43b,color:#000 style I fill:#ffd43b,color:#000 style J fill:#51cf66,color:#fff style K fill:#51cf66,color:#fff style L fill:#ffd43b,color:#000 style M fill:#51cf66,color:#fff style N fill:#51cf66,color:#fff style O fill:#ffd43b,color:#000 style P fill:#51cf66,color:#fff style Q fill:#51cf66,color:#fff style R fill:#74c0fc,color:#fff style S fill:#b197fc,color:#fff
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2. Segmentation

Detailed analysis of D. melanogaster Segmentation using the Programming Framework, revealing computational logic and regulatory patterns for body segment formation.

graph TD %% Segmentation Components A[Gap Gene Expression] --> B[Pair-Rule Genes] C[Segment Polarity] --> D[Engrailed Expression] E[Wingless Signaling] --> F[Segment Boundaries] G[Homeotic Genes] --> H[Segment Identity] %% Pair-Rule Expression B --> I[Even-Skipped] I --> J[Fushi Tarazu] J --> K[Segment Stripes] %% Segment Polarity D --> L[Engrailed/Wingless] L --> M[Cell Communication] M --> N[Segment Maintenance] %% Segment Identity F --> O[Antennapedia Complex] O --> P[Bithorax Complex] P --> Q[Segment Specification] %% Integration K --> R[Segmentation Program] N --> R Q --> R H --> R R --> S[Body Segmentation] %% Styling - Programming Framework Colors style A fill:#ff6b6b,color:#fff style C fill:#ff6b6b,color:#fff style E fill:#ff6b6b,color:#fff style G fill:#ff6b6b,color:#fff style B fill:#ffd43b,color:#000 style D fill:#ffd43b,color:#000 style F fill:#ffd43b,color:#000 style H fill:#ffd43b,color:#000 style I fill:#ffd43b,color:#000 style J fill:#51cf66,color:#fff style K fill:#51cf66,color:#fff style L fill:#ffd43b,color:#000 style M fill:#51cf66,color:#fff style N fill:#51cf66,color:#fff style O fill:#ffd43b,color:#000 style P fill:#51cf66,color:#fff style Q fill:#51cf66,color:#fff style R fill:#74c0fc,color:#fff style S fill:#b197fc,color:#fff
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3. Homeotic Regulation

Detailed analysis of D. melanogaster Homeotic Regulation using the Programming Framework, revealing computational logic and regulatory patterns for segment identity.

graph TD %% Homeotic Components A[Homeotic Genes] --> B[Antennapedia Complex] C[Bithorax Complex] --> D[Segment Identity] E[Polycomb Group] --> F[Gene Silencing] G[Trithorax Group] --> H[Gene Activation] %% Antennapedia Complex B --> I[Labial Expression] I --> J[Proboscipedia] J --> K[Deformed Expression] %% Bithorax Complex D --> L[Ultrabithorax] L --> M[Abdominal-A] M --> N[Abdominal-B] %% Epigenetic Control F --> O[Polycomb Repression] O --> P[Chromatin Modification] P --> Q[Gene Silencing] %% Integration K --> R[Homeotic Program] N --> R Q --> R H --> R R --> S[Segment Identity] %% Styling - Programming Framework Colors style A fill:#ff6b6b,color:#fff style C fill:#ff6b6b,color:#fff style E fill:#ff6b6b,color:#fff style G fill:#ff6b6b,color:#fff style B fill:#ffd43b,color:#000 style D fill:#ffd43b,color:#000 style F fill:#ffd43b,color:#000 style H fill:#ffd43b,color:#000 style I fill:#ffd43b,color:#000 style J fill:#51cf66,color:#fff style K fill:#51cf66,color:#fff style L fill:#ffd43b,color:#000 style M fill:#51cf66,color:#fff style N fill:#51cf66,color:#fff style O fill:#ffd43b,color:#000 style P fill:#51cf66,color:#fff style Q fill:#51cf66,color:#fff style R fill:#74c0fc,color:#fff style S fill:#b197fc,color:#fff
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4. Neural Development

Detailed analysis of D. melanogaster Neural Development using the Programming Framework, revealing computational logic and regulatory patterns for nervous system formation.

graph TD %% Neural Components A[Neural Precursors] --> B[Neurogenesis] C[Notch Signaling] --> D[Cell Fate Decision] E[Axon Guidance] --> F[Neural Circuits] G[Synapse Formation] --> H[Neural Function] %% Neurogenesis B --> I[Neural Progenitors] I --> J[Neuron/Glia Decision] J --> K[Neural Identity] %% Notch Signaling D --> L[Delta-Notch] L --> M[Lateral Inhibition] M --> N[Cell Fate Specification] %% Axon Guidance F --> O[Netrin Signaling] O --> P[Slit/Robo] P --> Q[Axon Pathfinding] %% Integration K --> R[Neural Program] N --> R Q --> R H --> R R --> S[Neural Circuit] %% Styling - Programming Framework Colors style A fill:#ff6b6b,color:#fff style C fill:#ff6b6b,color:#fff style E fill:#ff6b6b,color:#fff style G fill:#ff6b6b,color:#fff style B fill:#ffd43b,color:#000 style D fill:#ffd43b,color:#000 style F fill:#ffd43b,color:#000 style H fill:#ffd43b,color:#000 style I fill:#ffd43b,color:#000 style J fill:#51cf66,color:#fff style K fill:#51cf66,color:#fff style L fill:#ffd43b,color:#000 style M fill:#51cf66,color:#fff style N fill:#51cf66,color:#fff style O fill:#ffd43b,color:#000 style P fill:#51cf66,color:#fff style Q fill:#51cf66,color:#fff style R fill:#74c0fc,color:#fff style S fill:#b197fc,color:#fff
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5. Behavioral Genetics

Detailed analysis of D. melanogaster Behavioral Genetics using the Programming Framework, revealing computational logic and regulatory patterns for behavior generation.

graph TD %% Behavioral Components A[Genetic Background] --> B[Behavioral Genes] C[Neural Circuits] --> D[Behavioral Output] E[Environmental Cues] --> F[Behavioral Response] G[Learning Genes] --> H[Behavioral Plasticity] %% Behavioral Genes B --> I[Period Gene] I --> J[Clock Genes] J --> K[Circadian Behavior] %% Neural Circuits D --> L[Mushroom Bodies] L --> M[Central Complex] M --> N[Behavioral Control] %% Learning Genes F --> O[dunce Gene] O --> P[rutabaga Gene] P --> Q[Learning Ability] %% Integration K --> R[Behavioral Program] N --> R Q --> R H --> R R --> S[Behavioral Output] %% Styling - Programming Framework Colors style A fill:#ff6b6b,color:#fff style C fill:#ff6b6b,color:#fff style E fill:#ff6b6b,color:#fff style G fill:#ff6b6b,color:#fff style B fill:#ffd43b,color:#000 style D fill:#ffd43b,color:#000 style F fill:#ffd43b,color:#000 style H fill:#ffd43b,color:#000 style I fill:#ffd43b,color:#000 style J fill:#51cf66,color:#fff style K fill:#51cf66,color:#fff style L fill:#ffd43b,color:#000 style M fill:#51cf66,color:#fff style N fill:#51cf66,color:#fff style O fill:#ffd43b,color:#000 style P fill:#51cf66,color:#fff style Q fill:#51cf66,color:#fff style R fill:#74c0fc,color:#fff style S fill:#b197fc,color:#fff
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6. Circadian Rhythms

Detailed analysis of D. melanogaster Circadian Rhythms using the Programming Framework, revealing computational logic and regulatory patterns for 24-hour cycles.

graph TD %% Circadian Components A[Light Input] --> B[Clock Genes] C[Period Gene] --> D[Timeless Gene] E[Clock Gene] --> F[Cycle Gene] G[Feedback Loops] --> H[Rhythm Generation] %% Clock Genes B --> I[PER/TIM Complex] I --> J[Nuclear Entry] J --> K[Gene Repression] %% Feedback Regulation D --> L[CLK/CYC Complex] L --> M[Gene Activation] M --> N[PER/TIM Synthesis] %% Light Entrainment F --> O[Cryptochrome] O --> P[Light Sensing] P --> Q[Phase Reset] %% Integration K --> R[Circadian Program] N --> R Q --> R H --> R R --> S[24-Hour Rhythm] %% Styling - Programming Framework Colors style A fill:#ff6b6b,color:#fff style C fill:#ff6b6b,color:#fff style E fill:#ff6b6b,color:#fff style G fill:#ff6b6b,color:#fff style B fill:#ffd43b,color:#000 style D fill:#ffd43b,color:#000 style F fill:#ffd43b,color:#000 style H fill:#ffd43b,color:#000 style I fill:#ffd43b,color:#000 style J fill:#51cf66,color:#fff style K fill:#51cf66,color:#fff style L fill:#ffd43b,color:#000 style M fill:#51cf66,color:#fff style N fill:#51cf66,color:#fff style O fill:#ffd43b,color:#000 style P fill:#51cf66,color:#fff style Q fill:#51cf66,color:#fff style R fill:#74c0fc,color:#fff style S fill:#b197fc,color:#fff
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7. Learning & Memory

Detailed analysis of D. melanogaster Learning & Memory using the Programming Framework, revealing computational logic and regulatory patterns for behavioral plasticity.

graph TD %% Learning Components A[Experience] --> B[Neural Plasticity] C[cAMP Signaling] --> D[Memory Formation] E[Mushroom Bodies] --> F[Memory Storage] G[Retrieval] --> H[Behavioral Change] %% Neural Plasticity B --> I[Synaptic Changes] I --> J[Neural Circuits] J --> K[Circuit Modification] %% cAMP Signaling D --> L[dunce Gene] L --> M[rutabaga Gene] M --> N[cAMP Production] %% Memory Storage F --> O[Short-term Memory] O --> P[Long-term Memory] P --> Q[Memory Consolidation] %% Integration K --> R[Learning Program] N --> R Q --> R H --> R R --> S[Behavioral Adaptation] %% Styling - Programming Framework Colors style A fill:#ff6b6b,color:#fff style C fill:#ff6b6b,color:#fff style E fill:#ff6b6b,color:#fff style G fill:#ff6b6b,color:#fff style B fill:#ffd43b,color:#000 style D fill:#ffd43b,color:#000 style F fill:#ffd43b,color:#000 style H fill:#ffd43b,color:#000 style I fill:#ffd43b,color:#000 style J fill:#51cf66,color:#fff style K fill:#51cf66,color:#fff style L fill:#ffd43b,color:#000 style M fill:#51cf66,color:#fff style N fill:#51cf66,color:#fff style O fill:#ffd43b,color:#000 style P fill:#51cf66,color:#fff style Q fill:#51cf66,color:#fff style R fill:#74c0fc,color:#fff style S fill:#b197fc,color:#fff
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8. Genetic Regulation

Detailed analysis of D. melanogaster Genetic Regulation using the Programming Framework, revealing computational logic and regulatory patterns for gene expression control.

graph TD %% Regulation Components A[Transcription Factors] --> B[Gene Expression] C[Epigenetic Control] --> D[Chromatin Modification] E[MicroRNAs] --> F[Post-transcriptional Control] G[Alternative Splicing] --> H[Protein Diversity] %% Transcription Control B --> I[Enhancer Binding] I --> J[Promoter Activation] J --> K[Gene Transcription] %% Epigenetic Control D --> L[Histone Modification] L --> M[DNA Methylation] M --> N[Chromatin State] %% MicroRNA Control F --> O[miRNA Synthesis] O --> P[Target Recognition] P --> Q[mRNA Degradation] %% Integration K --> R[Regulation Program] N --> R Q --> R H --> R R --> S[Gene Expression Control] %% Styling - Programming Framework Colors style A fill:#ff6b6b,color:#fff style C fill:#ff6b6b,color:#fff style E fill:#ff6b6b,color:#fff style G fill:#ff6b6b,color:#fff style B fill:#ffd43b,color:#000 style D fill:#ffd43b,color:#000 style F fill:#ffd43b,color:#000 style H fill:#ffd43b,color:#000 style I fill:#ffd43b,color:#000 style J fill:#51cf66,color:#fff style K fill:#51cf66,color:#fff style L fill:#ffd43b,color:#000 style M fill:#51cf66,color:#fff style N fill:#51cf66,color:#fff style O fill:#ffd43b,color:#000 style P fill:#51cf66,color:#fff style Q fill:#51cf66,color:#fff style R fill:#74c0fc,color:#fff style S fill:#b197fc,color:#fff
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