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{
"papers": [
{
"_file": "paper_a.pdf",
"paper_title": "Test Paper A",
"risk_stance": "acceptable_with_uncertainty",
"risk_confidence": 0.72,
"risk_summary": "Contains partial carcinogenicity evidence.",
"extracted": {
"chemicals": ["Nicotine"],
"genotox_oecd_tg_in_vitro": ["OECD_TG_471_Bacterial Reverse mutation test(AMES test)"],
"genotox_oecd_tg_in_vivo": ["not_reported"],
"genotoxicity_result": "equivocal",
"genotoxicity_result_notes": "AMES mixed outcomes.",
"carcinogenicity_result": "insufficient_data",
"carcinogenicity_notes": "Long-term bioassay absent.",
"dose_metrics": ["NOAEL 10 mg/kg-day"],
"exposure_route": "oral",
"key_findings": "Potential DNA response observed.",
"conclusion": "Needs additional testing."
},
"evidence": [
{
"field": "genotoxicity_result",
"quote": "The AMES assay showed equivocal mutagenicity outcomes.",
"pages": "4-5"
},
{
"field": "dose_metrics",
"quote": "NOAEL was reported at 10 mg/kg-day.",
"pages": "6"
}
]
}
],
"toxra_extensions": {
"nlp_diagnostics": [],
"regulatory_gap_assessment": {},
"risk_calculation_refs": []
}
}
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