{
  "papers": [
    {
      "_file": "paper_a.pdf",
      "paper_title": "Test Paper A",
      "risk_stance": "acceptable_with_uncertainty",
      "risk_confidence": 0.72,
      "risk_summary": "Contains partial carcinogenicity evidence.",
      "extracted": {
        "chemicals": ["Nicotine"],
        "genotox_oecd_tg_in_vitro": ["OECD_TG_471_Bacterial Reverse mutation test(AMES test)"],
        "genotox_oecd_tg_in_vivo": ["not_reported"],
        "genotoxicity_result": "equivocal",
        "genotoxicity_result_notes": "AMES mixed outcomes.",
        "carcinogenicity_result": "insufficient_data",
        "carcinogenicity_notes": "Long-term bioassay absent.",
        "dose_metrics": ["NOAEL 10 mg/kg-day"],
        "exposure_route": "oral",
        "key_findings": "Potential DNA response observed.",
        "conclusion": "Needs additional testing."
      },
      "evidence": [
        {
          "field": "genotoxicity_result",
          "quote": "The AMES assay showed equivocal mutagenicity outcomes.",
          "pages": "4-5"
        },
        {
          "field": "dose_metrics",
          "quote": "NOAEL was reported at 10 mg/kg-day.",
          "pages": "6"
        }
      ]
    }
  ],
  "toxra_extensions": {
    "nlp_diagnostics": [],
    "regulatory_gap_assessment": {},
    "risk_calculation_refs": []
  }
}