diff --git "a/artifacts/part_a_canonical/algorithm_components.jsonl" "b/artifacts/part_a_canonical/algorithm_components.jsonl"
deleted file mode 100644--- "a/artifacts/part_a_canonical/algorithm_components.jsonl"
+++ /dev/null
@@ -1,6926 +0,0 @@
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-{"methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 2951}
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-{"methods_used": ["Machine learning: Unsupervised"], "related_diseases": ["Dermatology"], "phenotype_id": 3509}
-{"methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 3334}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4045}
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-{"data_period": {"start": "2022-10-01", "end": "2023-04-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 3948}
-{"data_period": {"start": "2004-10-01", "end": "2017-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 3960}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 3999}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4002}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4003}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4004}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4005}
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-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4008}
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-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4012}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4017}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4019}
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-{"adjudication_method": "N/A", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4021}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4023}
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-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4027}
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-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4031}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4037}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4039}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4044}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4047}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4054}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4060}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4070}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4073}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4075}
-{"validations": ["VA assigned e-codes were compared against e-coding prospectively conducted by the study team using the process followed by VHA coders. The team of coders was blinded to E-codes assigned by VHA coders during this process."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4077}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4079}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4080}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4081}
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-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4083}
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-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4088}
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-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3588}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3591}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3611}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3616}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3618}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3619}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3620}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3623}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3624}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3645}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3656}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3657}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3664}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3665}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3667}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3669}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3681}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3687}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3689}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3690}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3691}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3702}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3703}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3704}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3705}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3706}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3707}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3708}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3710}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3711}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3715}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3717}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3719}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3720}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3721}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3722}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3723}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3728}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3741}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3742}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3744}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3747}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3758}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3759}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3760}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3761}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3763}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3764}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3766}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3767}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3768}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3769}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3770}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3771}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3773}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3775}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3776}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3777}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3781}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3794}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3802}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3803}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3804}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3809}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3811}
-{"related_diseases": ["Gastrointestinal"], "phenotype_id": 3814}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3815}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3830}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3831}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3832}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3833}
-{"related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3834}
-{"related_diseases": ["Dermatology"], "phenotype_id": 3835}
-{"related_diseases": ["Cardiovascular"], "phenotype_id": 3838}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4091}
-{"data_period": {"start": "2002-01-01", "end": "2007-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4113}
-{"validations": ["We have performed a chart review of n=39 “difficult cases”. That is, MVP participants with either a) 1 ICD code for either MCI, AD, or dementia, or b) subjects with low to moderate AD case probability according to the Multimodal Automated Phenotype (MAP) algorithm (Liao et al. Am Med Inform Assoc, 2019). These were reviewed in tandem by Drs. Hauger and Meritt of the AD/MCI working group and classified as “Likely not”, “Possible”, or “Likely” cases of MCI, AD, and dementia. Chart review results were compared to the classifications according to the MAP algorithm and according to our ICD-code based definitions of MCI, AD, ADRD, and dementia (Table 2). The performance of the ICD code set in shown in \"Algorithm Performance Measures\". The authors also evaluated the suitability of our ICD code based phenotypes in genetic studies by testing their association with the APOE E4 isoform (the strongest AD genetic risk factor) in European-descent MVP subjects (Table 3)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4068}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4029}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4061}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 3998}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4071}
-{"methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 3671}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4097}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4048}
-{"methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 2979}
-{"methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 3030}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 3993}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 3994}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 3995}
-{"validations": ["A total of 200 patient charts were sampled from the MVP cohort through November 13, 2019 for the ICD codes associated with this phecode and chart review was carried out by 2 clinical adjudicators. For the validation of this cohort, a MAP cutoff value of 0.47 was applied."], "methods_used": ["Machine learning: Unsupervised"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 3762}
-{"validations": ["A total of 200 patient charts were sampled from the MVP cohort through November 13, 2019 for the ICD codes associated with this phecode and chart review was carried out by 2 clinical adjudicators. For the validation of this cohort, a MAP cutoff value of 0.21 was applied."], "methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 3564}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4125}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4053}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4007}
-{"validations": ["The algorithm was validated using the VA/CMS United States Renal Data System (USRDS) 2021 core dataset provided by VIReC. Multiple test flags were assessed (e.g. with different look-back periods) against a USRDS indicator (i.e. “true” case), and the flag with the highest c-statistic was selected as the final version."], "data_period": {"start": "2015-10-01", "end": "2019-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 3934}
-{"methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 3051}
-{"validations": ["A total of 100 patient charts were reviewed by 3 clinical adjudicators to create gold standard labels. Labels were subsequently used to validate the AD Plus definition including ICD-9 Codes - 331.0, 294.20, 294.21, 294.8, 290.0, 290.20, 290.21, 290.3 and ICD-10 Codes - G30.1, 30.8, 30.9, F03.90, F03.91, G 31.1 within the MVP_23.1 cohort.", "We have performed a chart review of n=39 “difficult cases”. That is, MVP participants with either a) 1 ICD code for either MCI, AD, or dementia, or b) subjects with low to moderate AD case probability according to the Multimodal Automated Phenotype (MAP) algorithm (Liao et al. Am Med Inform Assoc, 2019). These were reviewed in tandem by Drs. Hauger and Meritt of the AD/MCI working group and classified as “Likely not”, “Possible”, or “Likely” cases of MCI, AD, and dementia. Chart review results were compared to the classifications according to the MAP algorithm and according to our ICD-code based definitions of MCI, AD, ADRD, and dementia (Table 2). The performance of the ICD code set in shown in \"Algorithm Performance Measures\". The authors also evaluated the suitability of our ICD code based phenotypes in genetic studies by testing their association with the APOE E4 isoform (the strongest AD genetic risk factor) in European-descent MVP subjects (Table 3)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4033}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4000}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4235}
-{"data_period": {"start": "2013-01-01", "end": "2017-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4752}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4351}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4377}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4374}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12468}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4193}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4224}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4294}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12469}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 8628}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 8629}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 8630}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 8631}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 8632}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 8633}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 8634}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 8635}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 8636}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12471}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Gastrointestinal"], "phenotype_id": 8637}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4150}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4276}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12472}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic", "Gastrointestinal"], "phenotype_id": 4269}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4129}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4130}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4131}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4132}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12474}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4135}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4136}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4137}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4139}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4140}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4141}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4143}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4144}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4145}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4147}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4148}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4149}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4151}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4152}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4153}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4154}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4155}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4156}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4157}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4158}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4159}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4160}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4161}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4162}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4163}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4164}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4165}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4166}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4168}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4169}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4170}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4171}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4172}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4173}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4174}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4175}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12477}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4178}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4179}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4180}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4181}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4182}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4183}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4185}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4186}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4187}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4188}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4190}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4191}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4192}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4195}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 4196}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4198}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4199}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4200}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4201}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4203}
-{"methods_used": ["Other"], "phenotype_id": 4204}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 4205}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4206}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4208}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4209}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4210}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4211}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4212}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4213}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4214}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4216}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4217}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4218}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4219}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4220}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic", "Gastrointestinal"], "phenotype_id": 4221}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4222}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4223}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4225}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 4226}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic", "Gastrointestinal"], "phenotype_id": 4229}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4230}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4231}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4232}
-{"validations": ["Manual chart review by a urologist and a study coordinator. They manually validated bladder cancer surveillance procedures by referencing procedure notes on or around the date of cystoscopy and determined (1) if a cystoscopy was performed on the date indicated by the CDW data, (2) if it occurred after a bladder cancer diagnosis and thus was a surveillance procedure, (3) whether the provider who performed the procedure was correctly identified, and (4) whether the location of the procedure aligned with the extracted data."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4233}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4234}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4236}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4237}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4238}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4239}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4240}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4241}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4242}
-{"data_period": {"start": "2002-01-01", "end": "2012-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Dermatology"], "phenotype_id": 4243}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4244}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4245}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4246}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4247}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4248}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4249}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4250}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4251}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4252}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4253}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4254}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4255}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4256}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4257}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4258}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4259}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4260}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4261}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4262}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4263}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4264}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4265}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4266}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4268}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4270}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4271}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4272}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4273}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4274}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4275}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4277}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4278}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4279}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4280}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4281}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4282}
-{"adjudication_method": "N/A", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4283}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4286}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4287}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4288}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4289}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4290}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4291}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4292}
-{"data_period": {"start": "2015-10-01", "end": ""}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4295}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4296}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4297}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4298}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4299}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4300}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4301}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4302}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4303}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4304}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4305}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4306}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4307}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4308}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4309}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4310}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4311}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4312}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4313}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4314}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4315}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Gastrointestinal"], "phenotype_id": 4316}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4317}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4318}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4319}
-{"validations": ["VA assigned e-codes were compared against e-coding prospectively conducted by the study team using the process followed by VHA coders. The team of coders was blinded to E-codes assigned by VHA coders during this process."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4320}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4321}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4322}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4323}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 4325}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4326}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4327}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4330}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4331}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4333}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4176}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4334}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4335}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4336}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4337}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic", "Gastrointestinal"], "phenotype_id": 4338}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4339}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4340}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4341}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4343}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4344}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4345}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4346}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4347}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4348}
-{"methods_used": ["Machine learning: Supervised"], "phenotype_id": 4350}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4352}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4354}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12478}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4356}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4357}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4358}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4359}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4360}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4362}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4363}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4364}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4365}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4366}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4367}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4368}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4369}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4370}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4371}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4372}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4373}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4375}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4376}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4378}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4380}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4381}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4382}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4383}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 4384}
-{"methods_used": ["Other"], "phenotype_id": 4385}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4386}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4387}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4388}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4389}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4390}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4391}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic", "Gastrointestinal"], "phenotype_id": 4392}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4393}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4394}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4395}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4396}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4397}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4399}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4400}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4401}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4402}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 4403}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4404}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4405}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4406}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4407}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4409}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4410}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4411}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4412}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4413}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4414}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4415}
-{"adjudication_method": "Laboratory names were adjudicated following the method described in \"LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results\"", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4416}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4417}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4194}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12479}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4408}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4215}
-{"adjudication_method": "Boston Medication Adjudication Protocol - Using VA Pharmacy data, medications are reviewed and adjudicated by two subject matter experts, to ensure they are classified under the correct indication, drug class or generic name. Notes: Mental Health Medications are divided into two main generic types ANTIDEPRESSANT OTHER SUICIDE MED", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4328}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4722}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12480}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12481}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4128}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4349}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12482}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4267}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12483}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12484}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12485}
-{"validations": ["331 patients were chart reviewed and assigned gold standard labels, which were then compared to the ICD codes present. To calculate PPV and NPV, subjects were weighted by inverse probability of being sampled due to stratified sampling of patients. Chart review labels: ALD was defined as reports in the progress note of ALD or heavy alcohol consumption and evidence of liver injury."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4228}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4167}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12487}
-{"data_period": {"start": "2020-01-01", "end": "2021-01-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4749}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12488}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12489}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12490}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12491}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12492}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 10513}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12493}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 10526}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 10527}
-{"validations": ["The PTSD checklist (PCL), a self-reported questionnaire collected prospectively for this study, was used as the gold standard to compare against ICD codes. A PCL score greater than or equal to 50 was used to indicate a PTSD case."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 10533}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 10534}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 10535}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 10536}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 10537}
-{"data_period": {"start": "2002-01-01", "end": "2007-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4353}
-{"data_period": {"start": "2002-01-01", "end": "2007-12-31"}, "methods_used": ["Other", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4750}
-{"validations": ["Validation was performed against the Immunology Case Registry (ICR), a VA HIV-case registry and was considered the gold standard for “true positive”. The goal of the algorithm was to maximize the positive predictive value (PPV) of identifying a subject as HIV-infected, thus algorithm 2 was selected for use by the authors. The performance measures for Algorithm 1 are as follows:", "Validation was performed against the Immunology Case Registry (ICR), a VA HIV-case registry and was considered the gold standard for “true positive”. The goal of the algorithm was to maximize the positive predictive value (PPV) of identifying a subject as HIV-infected, thus algorithm 2 was selected for use by the authors. The performance measures for Algorithm 2 are as follows:"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 10515}
-{"validations": ["Chart review performed on 363 patients by 3 physicians."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 10523}
-{"data_period": {"start": "2002-01-01", "end": "2007-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4207}
-{"data_period": {"start": "2002-01-01", "end": "2007-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 4739}
-{"data_period": {"start": "2002-01-01", "end": "2007-12-31"}, "methods_used": ["Other", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4751}
-{"data_period": {"start": "2002-01-01", "end": "2007-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4284}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 10586}
-{"data_period": {"start": "2001-01-01", "end": "2015-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 10588}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 10589}
-{"data_period": {"start": "2001-01-01", "end": "2015-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 10590}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12495}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12496}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12497}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12498}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12501}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12502}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12506}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12507}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12514}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12515}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12516}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12518}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12519}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12522}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12523}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12524}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12525}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12526}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12527}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12529}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12530}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12531}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12532}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12533}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12534}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12535}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12536}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12537}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12538}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12539}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12540}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12541}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12542}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12543}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12544}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12545}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12546}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12547}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12549}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12556}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12557}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12562}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 12563}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 12565}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 12566}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12569}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12570}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12573}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12576}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12577}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12578}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12579}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12580}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12581}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12582}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12583}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12584}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12585}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12590}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12591}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12592}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12881}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12882}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12883}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12885}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12887}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12891}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12892}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4738}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12894}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12528}
-{"validations": ["A total of 100 patient charts were reviewed by 3 clinical adjudicators to create gold standard labels. Labels were subsequently used to validate the \"Strict AD\" definition including ICD-9 Codes - 331.0 and ICD-10 Codes - G30.1, 30.8, 30.9, within the MVP_23.1 cohort.", "We have performed a chart review of n=39 ��difficult cases”. That is, MVP participants with either a) 1 ICD code for either MCI, AD, or dementia, or b) subjects with low to moderate AD case probability according to the Multimodal Automated Phenotype (MAP) algorithm (Liao et al. Am Med Inform Assoc, 2019). These were reviewed in tandem by Drs. Hauger and Meritt of the AD/MCI working group and classified as “Likely not”, “Possible”, or “Likely” cases of MCI, AD, and dementia. Chart review results were compared to the classifications according to the MAP algorithm and according to our ICD-code based definitions of MCI, AD, ADRD, and dementia (Table 2). The performance of the ICD code set in shown in \"Algorithm Performance Measures\". The authors also evaluated the suitability of our ICD code based phenotypes in genetic studies by testing their association with the APOE E4 isoform (the strongest AD genetic risk factor) in European-descent MVP subjects (Table 3)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4177}
-{"validations": ["Each chart was reviewed by 2 reviewers, with ties broken by committee. The most recent AHA guidelines for stroke were used. 268 charts used in model development. For case–control studies, in which we were able to exclude uncertain stroke cases and controls, a case threshold of 0.75 and control threshold of 0.15 yielded the highest sensitivity and specificity, excluding uncertain patients (0.15≤P≤0.75). Performance metrics for this threshold shown below.", "Each chart was reviewed by 2 reviewers, with ties broken by committee. The most recent AHA guidelines for stroke were used. 268 charts used in model development. For longitudinal studies, in which a stroke phenotype was necessary for every patient, case and control thresholds at 0.5 were most accurate. Performance metrics for this threshold shown below."], "data_period": {"start": "1992-01-01", "end": "2014-01-01"}, "methods_used": ["Machine learning: Supervised"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4737}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12895}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4332}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12896}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12897}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12898}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4146}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4293}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Gastrointestinal"], "phenotype_id": 4285}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4723}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4725}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12901}
-{"validations": ["Chart review for ICD-9 codes performed on 876 patients by one clinician with 10 charts independently reviewed by a second reviewer (95% agreement on data elements abstracted). Visit https://medicine.yale.edu/intmed/vacs/ for more detailed information."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 10522}
-{"validations": ["Positive antibody test was considered the gold standard."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 10519}
-{"validations": ["Chart review for ICD-9 codes performed on 876 patients by one clinician with 10 charts independently reviewed by a second reviewer (95% agreement on data elements abstracted). Visit https://medicine.yale.edu/intmed/vacs/ for more detailed information."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 10524}
-{"validations": ["Chart review for ICD-9 codes performed on 876 patients by one clinician with 10 charts independently reviewed by a second reviewer (95% agreement on data elements abstracted). Visit https://medicine.yale.edu/intmed/vacs/ for more detailed information."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 10521}
-{"validations": ["Chart review for ICD-9 codes performed on 876 patients by one clinician with 10 charts independently reviewed by a second reviewer (95% agreement on data elements abstracted). Visit https://medicine.yale.edu/intmed/vacs/ for more detailed information."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 10516}
-{"validations": ["Required 2 separate outpatient codes or 1 inpatient code for the condition before counting the condition as present"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 10520}
-{"validations": ["Chart review for ICD-9 codes performed on 876 patients by one clinician with 10 charts independently reviewed by a second reviewer (95% agreement on data elements abstracted). Visit https://medicine.yale.edu/intmed/vacs/ for more detailed information."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 10518}
-{"validations": ["Chart review for ICD-9 codes performed on 876 patients by one clinician with 10 charts independently reviewed by a second reviewer (95% agreement on data elements abstracted). Visit https://medicine.yale.edu/intmed/vacs/ for more detailed information."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 10517}
-{"validations": ["A total of 100 patient charts were reviewed by 3 clinical adjudicators to create gold standard labels. Labels were subsequently used to validate the Phecode within the MVP_23.1 cohort."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12936}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12906}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12911}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12912}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 4202}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4324}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4138}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12913}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12914}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12915}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12918}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12919}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12920}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12922}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12923}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12924}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12925}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12926}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12927}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12930}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12931}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4189}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4197}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12932}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12933}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13010}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13014}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13017}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4355}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4329}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13018}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13019}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13020}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13021}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13022}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13023}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13024}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13025}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13026}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13027}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13028}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13029}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13030}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13032}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13033}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13034}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13035}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13037}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13039}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13043}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13044}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13045}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13046}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13047}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13048}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13049}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13050}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13053}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13055}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13056}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13057}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13058}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13059}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13060}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13062}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13065}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13066}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13067}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13070}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13071}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 4721}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 4133}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13072}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13073}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13074}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13075}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13076}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13078}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13079}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13080}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13081}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13082}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13083}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13084}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13085}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13086}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13087}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13088}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13089}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13092}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13094}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13095}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13096}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13097}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13098}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13099}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13100}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13101}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13103}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13104}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13105}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13106}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13107}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13108}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13109}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13110}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13111}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13112}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13114}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13115}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13116}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13117}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13118}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13119}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13121}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13122}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13123}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13124}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13125}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13126}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13127}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13128}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 13051}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13129}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13130}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13131}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13132}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13134}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13135}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13136}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13137}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13138}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13139}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12470}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12473}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12475}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12476}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12486}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12494}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12499}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12500}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12503}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12504}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12505}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12508}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12509}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12510}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12511}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12512}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12513}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12517}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12520}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12521}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12548}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12550}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12551}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12552}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12553}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12554}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12555}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 12558}
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-{"validations": ["A total of 100 patient charts were sampled from the VA- Million Veterans Program cohort through November 13, 2019 for the ICD codes associated with this phecode and chart review was carried out by 3 clinical adjudicators."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 13217}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13246}
-{"validations": ["A total of 200 patient charts were sampled from the VA Million Veteran Program (MVP) cohort through November 13, 2019 for the ICD codes associated with this phecode and chart review was carried out by 2 clinical adjudicators."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13247}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13295}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13296}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13297}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13298}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13299}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13300}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13301}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13302}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13303}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13304}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13305}
-{"validations": ["A total of 200 patient charts were sampled from the VA Million Veteran Program (MVP) cohort through November 13, 2019 for the ICD codes associated with this phecode and chart review was carried out by 2 clinical adjudicators."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 13306}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15436}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15437}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15438}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15439}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15440}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15441}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15442}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15443}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15444}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15445}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15446}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15447}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15448}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15449}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15450}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15451}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15452}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15453}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15454}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15455}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15456}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15457}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15458}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15459}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15460}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15461}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15462}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15463}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15464}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15465}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15466}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15467}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15468}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15469}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15470}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15471}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15472}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15473}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15474}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15475}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15476}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15477}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15478}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15479}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15480}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15481}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15482}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15483}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15484}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15485}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15486}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15487}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15488}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15489}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15490}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15491}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15492}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15493}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15494}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15495}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15496}
-{"validations": ["28,425 cases initially identified using locally-maintained registry lists matched against initial (less complex/comprehensive algorithm pull of 210 stop, TS22, ICD9/10 codes): 29,307. Overlapped the local lists with the initial pull. Cases that were on BOTH, were not chart reviewed in between January and May 2018 by 24 SCI/D Informatics staff from the field, and were labeled true case or false positive/ineligible. The “gold standard” data set included all 36,163 cases, with each case labeled “eligible” (n=32,091), “not eligible” (n=3,984), or “pending” (n=88). The VSSC programmer, SMEs, and field staff worked with the 11SCID national program office to balance false positives versus false negatives and the best criteria was two (2) of the workload categories. One (1) workload category brought in too many false positives. Three (3) left out too many true cases. We settled on 2. An operational review was conducted at the end of FY19 that included data validation of 14,133 (10,788 SCI/D,"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16805}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16806}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15497}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15498}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15499}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15500}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15501}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15502}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15503}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15504}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15505}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15506}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15507}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15508}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15509}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15510}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15511}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15512}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15513}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15514}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15515}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15516}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15517}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15518}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15519}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15520}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15521}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15522}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15523}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15524}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15525}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15526}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15527}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15528}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15529}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15530}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15531}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15532}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15533}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15534}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15535}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15536}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15537}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15538}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15539}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15540}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15541}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15542}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15543}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15544}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15545}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15546}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15547}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15548}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15549}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15550}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15551}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15552}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15553}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15554}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15555}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15556}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15557}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15558}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15559}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15560}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15561}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15562}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15563}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15564}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15565}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15566}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15567}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15568}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15569}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15570}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15571}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15572}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15573}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15574}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15575}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15576}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15577}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15578}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15579}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15580}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15581}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15582}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15583}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15584}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15585}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15586}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15587}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15588}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15589}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15590}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15591}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15592}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15593}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15594}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15595}
-{"validations": ["Each chart was reviewed by 1 reviewer, with 2 reviewers assessing in total 48 inpatient records with PE codes in any position. PE codes were pre-selected based on published literature review findings. Reviewers assessed the positive predictive value of PE codes overall and by position, using discharge summaries, clinical progress notes, lab and imaging results, and hospitalization records to search for evidence of recent event. For 1st set of Algorithm Performance Measures: ICD-9-CM PE codes are in the primary or secondary diagnostic position.", "For 2nd set of Algorithm Performance Measures: ICD-9-CM PE codes are in any diagnostic position"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16013}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15596}
-{"adjudication_method": "Our labs were first developed through SQL queries for related labs including: Hepatitis C antibody labs Hepatitis C viral load labs Reviewer adjudicated labs based on the LabChemTestName, comparing labs to those on HIV, Hepatitis, and Related Conditions Programs (HHRC), Advanced Liver Disease (ALD) Dashboard Coordinator’s, and the Million Veterans Projects (MVP)’s lab phonotypes. Any disagreements were discussed between groups and were reviewed through a sample of EHR records when needed.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16057}
-{"adjudication_method": "Our labs were first developed through SQL queries for related labs including: Hepatitis B core antibody labs (IgG or Total, excluding IgM only labs) Hepatitis B surface antigen labs Hepatitis B viral load labs Reviewers adjudicated labs based on the LabChemTestName, comparing labs to those on HIV, Hepatitis, and Related Conditions Programs (HHRC), Advanced Liver Disease (ALD) Dashboard Coordinator’s, and the Million Veterans Projects (MVP)’s lab phenotypes. Any disagreements were discussed between groups and were reviewed through a sample of EHR records when needed.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16058}
-{"adjudication_method": "Reviewer adjudicated labs based on the LabChemTestName, comparing labs to those on HIV, Hepatitis, and Related Conditions Programs (HHRC), Advanced Liver Disease (ALD) Dashboard Coordinator’s, and the Million Veterans Projects (MVP)’s lab phonotypes. Any disagreements were discussed between groups and were reviewed through a sample of EHR records when needed.", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15879}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16918}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15597}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15598}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16937}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15905}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15904}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15599}
-{"adjudication_method": "N/A", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16312}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15600}
-{"validations": ["We randomly divided the cohort into training (algorithm development, 80%), validation (algorithm refinement, 10%), and test (algorithm performance evaluation, 10%) datasets. Two trained staff members (VJ, CG), following a patient chart review guide and supervised by a clinician (MB), independently reviewed 20 random charts from the validation dataset to determine if patients with opioid use disorder had evidence of medication-assisted treatment (MAT) over a 6-month period. After minor modifications to the algorithm, they reviewed 20 different random charts from the test dataset. The chart review-generated classification was then compared to the final phenotyping algorithm classification of MAT using the test dataset to determine the algorithm’s performance (see algorithm performance metrics). Third Set: Naltrexone* Only 1 patient out of 20 reviewed had any evidence of naltrexone.", "We randomly divided the cohort into training (algorithm development, 80%), validation (algorithm refinement, 10%), and test (algorithm performance evaluation, 10%) datasets. Two trained staff members (VJ, CG), following a patient chart review guide and supervised by a clinician (MB), independently reviewed 20 random charts from the validation dataset to determine if patients with opioid use disorder had evidence of medication-assisted treatment (MAT) over a 6-month period. After minor modifications to the algorithm, they reviewed 20 different random charts from the test dataset. The chart review-generated classification was then compared to the final phenotyping algorithm classification of MAT using the test dataset to determine the algorithm’s performance (see algorithm performance metrics). First Set: Methadone", "We randomly divided the cohort into training (algorithm development, 80%), validation (algorithm refinement, 10%), and test (algorithm performance evaluation, 10%) datasets. Two trained staff members (VJ, CG), following a patient chart review guide and supervised by a clinician (MB), independently reviewed 20 random charts from the validation dataset to determine if patients with opioid use disorder had evidence of medication-assisted treatment (MAT) over a 6-month period. After minor modifications to the algorithm, they reviewed 20 different random charts from the test dataset. The chart review-generated classification was then compared to the final phenotyping algorithm classification of MAT using the test dataset to determine the algorithm’s performance (see algorithm performance metrics). Second Set: Buprenorphine"], "data_period": {"start": "2015-10-01", "end": "2018-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16306}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16944}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16946}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 16947}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16968}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16969}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15601}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15602}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15603}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15604}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15605}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15606}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15607}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15608}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15609}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15610}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15611}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15612}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15613}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15614}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15615}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15616}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15617}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15618}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15619}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15620}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15621}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15622}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15623}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15624}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16938}
-{"validations": ["We applied combinations of ICD code algorithms to this base cohort. We selected a random sample of subjects who were algorithm positive (ie, candidates with EoE cases), along with a random sample of subjects who were algorithm negative (ie, candidate non-EoE controls), to evaluate if these algorithm-positive individuals satisfied the definition of a true EoE diagnosis (see True Eosinophilic Esophagitis Case Definition section later). A random number generator was used to select individuals at random and to mix candidate cases and controls so that the reviewer was blinded to the algorithm-positive or algorithm-negative status during the manual chart review process. After manual chart review, algorithm performance was assessed by calculating the PPV among candidate EoE cases."], "data_period": {"start": "1999-10-01", "end": "2020-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 16942}
-{"data_period": {"start": "2010-01-01", "end": "2017-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16943}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16945}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16952}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16953}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16954}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16955}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15625}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15626}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15627}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15628}
-{"data_period": {"start": "2003-08-01", "end": "2018-11-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15872}
-{"data_period": {"start": "2003-08-01", "end": "2018-11-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15873}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 16133}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15876}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15877}
-{"data_period": {"start": "", "end": "2021-06-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15880}
-{"data_period": {"start": "", "end": "2021-06-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15881}
-{"data_period": {"start": "", "end": "2021-06-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15882}
-{"data_period": {"start": "", "end": "2021-06-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 15883}
-{"data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15887}
-{"data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15884}
-{"data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 15886}
-{"data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15885}
-{"data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15888}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15900}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15906}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16970}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15909}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15912}
-{"data_period": {"start": "2020-01-01", "end": "2021-01-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15913}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16971}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16972}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15917}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15918}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15919}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15920}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15921}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15922}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15923}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15924}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 15925}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 15926}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15927}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15928}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15929}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15930}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15931}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15932}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15933}
-{"data_period": {"start": "2008-01-01", "end": "2016-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15934}
-{"validations": ["The author compared ICD-9 code performance against 1) the entire dataset of clinician confirmed TBI cases and non cases and 2) the subset of confirmed TBI cases. Confirmed cases and non-cases were identified by applying the the American Congress of Rehabilitative Medicine criteria to the Comprehensive TBI Evaluation (CTBIE) responses."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15935}
-{"validations": ["The author compared ICD-9 code performance against 1) the entire dataset of clinician confirmed TBI cases and non cases and 2) the subset of confirmed TBI cases. Confirmed cases and non-cases were identified by applying the the American Congress of Rehabilitative Medicine criteria to the Comprehensive TBI Evaluation (CTBIE) responses. Confirmed TBI Cases", "The author compared ICD-9 code performance against 1) the entire dataset of clinician confirmed TBI cases and non cases and 2) the subset of confirmed TBI cases. Confirmed cases and non-cases were identified by applying the the American Congress of Rehabilitative Medicine criteria to the Comprehensive TBI Evaluation (CTBIE) responses. Entire Dataset"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15936}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15938}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 15939}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15940}
-{"validations": ["VA assigned e-codes were compared against e-coding prospectively conducted by the study team using the process followed by VHA coders. The team of coders was blinded to E-codes assigned by VHA coders during this process."], "data_period": {"start": "2001-10-01", "end": "2006-01-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15941}
-{"data_period": {"start": "2001-01-01", "end": "2015-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15943}
-{"data_period": {"start": "2001-01-01", "end": "2015-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15944}
-{"data_period": {"start": "2001-01-01", "end": "2015-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15945}
-{"data_period": {"start": "2012-01-01", "end": "2020-04-12"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15946}
-{"validations": ["VA assigned e-codes were compared against e-coding prospectively conducted by the study team using the process followed by VHA coders. The team of coders was blinded to E-codes assigned by VHA coders during this process."], "data_period": {"start": "2001-10-01", "end": "2006-01-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15947}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15948}
-{"data_period": {"start": "2012-01-01", "end": "2020-04-12"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15955}
-{"validations": ["We hypothesized that individuals with a diagnosis of depression would have significantly lower scores on the mental component score (MCS) of the Veterans RAND 12 health status measure. To validate the relationship between depression diagnosis and self-reported mental health symptoms, we compared VR-12 MCS scores for Veterans with and without a diagnosis of depression (FY18) the year prior to survey administration (FY19). Median MCS12 scores for the cohort were significantly different (p<0.0001) between those who did (n=511, MCS12 = 29.5) and did not (n=2092, MCS12 = 38.9) have a diagnosis of depression in either VA or DoD records the previous year. Lower MCS12 scores indicate report of worse mental health, and a difference of 2.5 points is considered clinically meaningful"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15951}
-{"data_period": {"start": "2001-10-01", "end": "2015-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15914}
-{"validations": ["Smoking From Electronic Medical Record Health Factors Data Compared With Self-report on LHS survey for the Subset of National VACS Virtual Cohort Subset Who Completed the 1999 Large Health Study Survey (VACS-VC/LHS) as Gold Standard (n = 11,355) Never Former Current Never, n(%) 2,136 (82) 973 (29) 179 (3) Former, n(%) 246 (9) 1,612 (48) 459 (8) Current, n(%) 213 (8) 760 (23) 4,777 (88)", "Two sources of self-reported smoking status were used as the gold standard: 6,816 HIV-infected and -uninfected participants in the 8-site Veterans Aging Cohort Study (VACS) A subset of 13,689 participants from the national VACS Virtual Cohort (VACS-VC) who also completed the 1999 Large Health Study (LHS) survey Smoking From Electronic Medical Record Health Factors Data Compared With Self-report on 8-Site Veterans Aging Cohort Study (VACS-8) Survey as Gold Standard (n = 6,412) Never Former Current Never, n(%) 1,364 (84) 372 (24) 40 (1) Former, n(%) 117 (7) 663 (43) 119 (4) Current, n(%) 150 (9) 519 (33) 3,068 (95)"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15954}
-{"validations": ["Retrospective, cross-sectional examination of EMRs was conducted, using a combination of administrative data, chart abstraction, and review/consensus by board-certified neuropsychologists. The sample was restricted to those diagnosed prior to age 65 N = 1,724 cases. From the resultant sample, random selection of ~ 10% (176 cases) for chart abstraction."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15963}
-{"validations": ["100 random charts reviewed to determine prevalence of AIS in the VA. Each chart was reviewed by 2 reviewers, with ties broken by committee. The most recent AHA guidelines for stroke were used. 230 charts were used in model development. Clinicians classified charts as definite AIS, possible AIS, or no AIS. If the probability is cut at 0.77, the performance measures are as below. If assuming that the filter negative patients don't have AIS, the model achieves projected NPV of 0.972. For the AUC, possible AIS cases were grouped with definite AIS"], "methods_used": ["Machine learning: Unsupervised"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15967}
-{"data_period": {"start": "", "end": "2017-05-24"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15968}
-{"validations": ["After data abstraction, data forms were independently reviewed by two arbitrators with expertise in chronic liver diseases. Each determined if hepatic decompensation was present and recorded the date each condition was first identified. They then decided whether the event was definite, possible, or had not occurred. Hepatic decompensation was considered to have occurred at the earliest date any diagnosis consistent with the event was documented. Disagreement on classification or date resulted in review by a third arbitrator to adjudicate the event. Definitions for each hepatic decompensation event were based on guidelines by the AASLD and EASL. Below are the performance characteristics for any ICD code, for performance metrics on individual codes please see paper", "Below are the performance characteristics for any laboratory abnormality, for performance metrics on individual codes please see paper"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15981}
-{"validations": ["Chart review vs. SQL tool: Team created reference set of 199 documents to compare against SQL tool. A pulmonologist reviewed cases where there were multiple FEV1 entries in the document and recoded the value closest to the note date. SQL Tool vs. structured CDW data: FEV1 obtained from the CDW was compared to values found using the SQL tool Tool Performance metrics listed below, With Chart Review as a Reference."], "data_period": {"start": "1996-01-01", "end": "2015-12-31"}, "methods_used": ["Machine learning: Supervised"], "phenotype_id": 15982}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 15987}
-{"data_period": {"start": "1999-10-01", "end": "2020-01-16"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15988}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15957}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 15958}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15959}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 15960}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15961}
-{"validations": ["Each chart was reviewed by 2 reviewers, with ties broken by committee. The most recent AHA guidelines for stroke were used. 268 charts used in model development."], "data_period": {"start": "1992-01-01", "end": "2014-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15969}
-{"validations": ["Each chart was reviewed by 2 reviewers, with ties broken by committee. The most recent AHA guidelines for stroke were used. 260 charts used in model development."], "data_period": {"start": "1992-01-01", "end": "2014-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15970}
-{"data_period": {"start": "2008-01-01", "end": "2018-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic", "Gastrointestinal"], "phenotype_id": 15978}
-{"data_period": {"start": "2005-01-01", "end": "2009-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15992}
-{"data_period": {"start": "2002-01-01", "end": "2020-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15995}
-{"validations": ["100 random charts reviewed to determine prevalence of RA in the VA. Each chart was reviewed by 2 reviewers, with ties broken by committee. 227 charts were used in model development. Clinicians classified charts as definite RA, possible RA, or no RA. Algorithm Performance Measures: AUC for validation set: 0.933 (Possible RA cases grouped with definite RA) If the probability is cut at 0.631, the model achieves PPV of 0.903 and NPV of 0.851 on the validation set. Assuming that the filter negative patients don't have RA, the model achieves projected NPV of 0.997."], "methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 15997}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16002}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16003}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16005}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16006}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16007}
-{"validations": ["Correlated TBI severity with epilepsy, early onset dementia (dose response effect). Logistic regression analyses to ID relationship between TBI severity and outcomes that should be associated with more severe TBI. Found TBI severity associated with epilepsy and early onset dementia."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16008}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16009}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16010}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16011}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16012}
-{"methods_used": ["Other"], "phenotype_id": 16043}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16059}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16060}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16061}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16078}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16077}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16102}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16103}
-{"adjudication_method": "N/A", "adjudication_performed": true, "data_period": {"start": "2000-01-01", "end": "2021-03-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16110}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16111}
-{"validations": ["We validated the NLP and ML algorithms separately, based on a sample of 200 patients. We then performed an additional validation based on the chart review of another sample of 200 patients. Please see Additional Information for attached plots of performance at different thresholds on a population with at 1 HF ICD code."], "methods_used": ["Machine learning: Supervised"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16116}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15962}
-{"validations": ["Correlated TBI severity with epilepsy, early onset dementia (dose response effect). Logistic regression analyses to ID relationship between TBI severity and outcomes that should be associated with more severe TBI. Found TBI severity associated with epilepsy and early onset dementia."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16126}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16127}
-{"validations": ["We conducted chart review of earlier versions of the algorithm and found PPV of .92-.94. For this version we compared epilepsy status for those in a cohort where epilepsy was identified using natural language processing for Veterans who underwent video EEG monitoring (gold standard); all 100 who were in both cohorts were validated as having epilepsy (PPV 1.0) Using combined survey and health record data, tested hypotheses examining lifetime history of TBI and the differential impacts of TBI, epilepsy, and PTE on quality of life."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16128}
-{"validations": ["The first phase of validation was a review of 100 charts randomly selected from the VA Million Mart, to see whether using ICD code for OSA was sufficiently sensitive to capture everyone who had OSA. We saw that of 10 patients considered to have definite (n=5) or possible (n=5) OSA based on expert chart review, 9 (90.0%) had at least one ICD code for OSA. Of 90 patients without definite or possible OSA by expert chart review, only 2 (2.2%) had an ICD code for OSA. The second phase of validation was a review of 100 charts of individuals from MVP with at least one OSA ICD code. We computed performance measures within the latter set of individuals (with at least one OSA ICD code). Specificity and NPV are not provided, since all patients with zero values for MAP_OSA were excluded from the test set."], "methods_used": ["Machine learning: Supervised", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Endocrine/Metabolic"], "phenotype_id": 16130}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16132}
-{"validations": ["A chart review of 200 patient charts was completed by 2 clinical adjudicators."], "methods_used": ["Machine learning: Semi-Supervised"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16140}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16141}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16149}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15977}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16146}
-{"validations": ["Validated AUDIT-C trajectory against 1) direct alcohol biomarker (Phosphatidylethanol - PEth) and 2) established molecular genetic factor that is protective against harmful alcohol use [rs2066702 - a common missense (Arg369Cys) polymorphism of the ADH1B gene]. Performance Measures: AUDIT-C trajectory was associated with PEth (p<.05). Among African Americans (36% with the protective ADH1B allele), the association of rs2066702 with AUDIT-C trajectory was statistically significant (p<.05)."], "methods_used": ["Other"], "phenotype_id": 15991}
-{"validations": ["Chart review for ICD-9 codes performed on 876 patients by one clinician with 10 charts independently reviewed by a second reviewer (95% agreement on data elements abstracted). Visit https://medicine.yale.edu/intmed/vacs/ for more detailed information."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16056}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16182}
-{"validations": ["Veterans with multimorbidity patterns (cardiovascular and metabolic diseases, psychiatric and substance use disorders, chronic lung disease, and multisystem impairment) had higher rates of death, emergency department use and hospitalizations than veterans with minimal comorbidity. See Kaplan-Meier curves in manuscript."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Endocrine/Metabolic"], "phenotype_id": 16150}
-{"validations": ["Two independent reviewers adjudicated 447 of these hospitalizations to determine the accuracy of each code. See table 3 in manuscript for detailed performance metrics."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16152}
-{"validations": ["Not validated against a known standard, but two measures of persistence (total days and continuous fill) were tested for oral hypoglycemics, full results PMID: 21779543. Subsequent analyses found that persistence above 80% measured by continuous fill was associated with glycemic control (PMID: 20388863)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16153}
-{"data_period": {"start": "2013-01-01", "end": "2017-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16154}
-{"validations": ["Algorithm validated against self-reported smoking status from MVP Questionnaire Data. Results of LASSO algorithm performance on validation set for \"Current Smoker\"", "Algorithm validated against self-reported smoking status from MVP Questionnaire Data. Results of LASSO algorithm performance on validation set for \"Former Smoker\"", "Algorithm validated against self-reported smoking status from MVP Questionnaire Data. Results of LASSO algorithm performance on validation set for \"Never Smoker\""], "methods_used": ["Machine learning: Supervised"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16158}
-{"validations": ["100 random charts reviewed to determine prevalence of MI in the VA. 300 charts that satisfy broad MI filter reviewed by 4 clinicians. All charts reviewed by 2 clinicians. Clinicians classified charts as definite MI, possible MI, or no MI. Algorithm Performance Measures: AUC for validation set: 0.871 (Possible MI cases grouped with definite MI) If the probability is cut at 0.758, the model achieves PPV of 0.908 and NPV of 0.679 on validation set. Assuming that the filter negative patients don't have MI, the model achieves projected NPV of 0.97."], "methods_used": ["Machine learning: Unsupervised"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15986}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16121}
-{"validations": ["Validation of VASIC algorithm was performed with and extensive review of VHA clinical notes for a random sample of 200 patients. Adjudication was conducted by three clinical subject matter experts, and each patient record was examined by at least two reviewers. Consistency across reviewers was analyzed using Cohen’s Kappa statistic. The validated algorithm was retrained using the gold-standard labels and applied to 94,595 SARS-CoV-2 positive Veterans at day 30 post-infection. The interrater reliability of the VASIC algorithm, as measured by Kappa statistic, showed high concordance (0.83) and resulted in high PPV, sensitivity and specificity across mild, moderate, and severe categories: mild vs others (0.86, 0.73, 0.92); moderate vs others (0.92, 0.87, 0.84); and severe vs others (0.67, 0.97, 0.92)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16189}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16190}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16191}
-{"adjudication_method": "Boston Lab Adjudication Method", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 16192}
-{"validations": ["Chart reviews were performed to validate output from the ML classifier for Falls (see performance metrics below). The ML classifier predicted Falls and chart review validated the output. For risk of fractures, T-score was extracted using NLP for from radiology reports. Chart review validated NLP output. A second cohort was used to validate the phenotype definition who consisted of Veterans with HIV who were 50 years of age or older who were at elevated risk of having decreased bone mineral density."], "data_period": {"start": "2012-01-01", "end": "2015-12-31"}, "methods_used": ["Machine learning: Supervised", "Other"], "phenotype_id": 16204}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16248}
-{"adjudication_method": "PMID: 28505339 https://pubmed.ncbi.nlm.nih.gov/28505339/", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16249}
-{"validations": ["During a median follow-up of 4 years, 23,829 cases of kidney failure were observed. The original KFREs achieved excellent discrimination (ability to differentiate those who developed kidney failure from those who did not) across all cohorts (overall C statistic, 0.90 (95% CI 0.89–0.92) at 2 years and 0.88 (95% CI 0.86–0.90) at 5 years); discrimination in subgroups by age, race, and diabetes status was similar. There was no improvement with the pooled equations. Calibration (the difference between observed and predicted risk) was adequate in North American cohorts, but the original KFREs overestimated risk in some non-North American cohorts. Addition of a calibration factor that lowered the baseline risk by 32.9% at 2 years and 16.5% at 5 years improved the calibration in 12/15 and 10/13 non-North American cohorts at 2 and 5 years, respectively (p=0.04 and p=0.02)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16254}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16255}
-{"validations": ["Manual chart review of 50 patients was performed at local Cleveland and RI VA hospitals for initial algorithm development, with high overall positive and negative predictive values (93% and 95%, respectively).", "The algorithm was then optimized in a data cube using a variety of approaches including adjusting inclusion age thresholds by examining previously-reported genetic associations for CFH (rs10801555, a proxy for rs1061170) and ARMS2 (rs10490924). The algorithm with the smallest p-values for the known genetic associations was selected for downstream and on-going AMD genomic discovery efforts."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 16256}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16207}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16258}
-{"data_period": {"start": "2000-10-01", "end": "2022-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16260}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16261}
-{"adjudication_method": "Boston Lab Adjudication Protocol", "adjudication_performed": true, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16262}
-{"data_period": {"start": "2006-01-01", "end": "2021-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16264}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16294}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16295}
-{"data_period": {"start": "2010-01-01", "end": "2021-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15875}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16305}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15990}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16309}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16310}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16311}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15629}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16314}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16142}
-{"validations": ["In GWAS we found variants in several addiction-related genes that may be associated with the phenotype, although they did not meet genome-wide statistical significance. We also characterized the phenotype by examining potential correlates that were identified a priori. The most robust phenotypic predictor of buprenorphine treatment response was intravenous drug use, a proxy for which was HCV infection."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16184}
-{"validations": ["Another clinical expert annotated an extra set of 1000 snippets and the machine learning model was applied to those snippets to identify the use of CIH. The results were compared to the annotations to calculate the classification performance."], "data_period": {"start": "2010-01-01", "end": "2013-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16321}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16137}
-{"data_period": {"start": "2007-10-01", "end": "2019-10-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16335}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16336}
-{"data_period": {"start": "2008-01-01", "end": "2016-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16346}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16347}
-{"validations": ["Agreement of “Gold Standard” for Unhealthy Alcohol Use Based in the past year was defined as having a CIDI-SAM diagnosis of alcohol abuse or dependence in the past year or meeting criteria for risky drinking based on the 30 day Time Line Follow Back (TLFB) interview. These questionnaires were administered by telephone to a sub-set of VACS participants. Various cutoffs for the AUDIT, AUDIT-C, and heavy episodic drinking were compared to the reference standards. Metrics below are based on AUDIT-C 3+ or heavy episodic drinking, please see manuscript for full list of performance metrics at various cutoffs."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16350}
-{"validations": ["The “Gold Standard” for Risky Drinking was based on the 30 day Time Line Follow Back (TLFB) interview. We defined risky drinking as consuming >14 drinks over any consecutive 7-day period or >4 drinks in 1 day based on the guidelines recommended by the National Institute on Alcohol Abuse and Alcoholism to identify those at risk for alcohol-related problems. Various cutoffs for the AUDIT, AUDIT-C, and heavy episodic drinking were compared to the reference standards. Metrics below are based on AUDIT-C 4+ or heavy episodic drinking, please see manuscript for full list of performance metrics at various cutoffs."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16351}
-{"validations": ["A manual review of a subset of EHR data from CDW was performed by an author to determine the accuracy of the phenotyping algorithm. Using the phenotyping algorithm, the following sets of potential incident diagnoses were detected: 268 patients with breast cancer (BC) were identified from oncology. 635 patients were identified excluding in situ by ICD only. 270 patients were identified excluding in situ based on ICD and compatible CPT codes. 338 patients were diagnosed based on either oncology or compatible ICD and CPT codes. Detailed summary of validation measures provided in attachment."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16162}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15973}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16134}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15999}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16253}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16250}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 16138}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16183}
-{"validations": ["Manual chart review was performed by two trained nurse chart abstractors with a vascular surgeon reviewing discordant cases; the results of chart review for 50 cases and 50 controls otherwise representative of the overall cohort were used for determining the sensitivity and specificity of the phenotyping algorithm. Sensitivity 100% (95% CI = 89.8–100%) Specificity 88% (95% confidence interval(CI) = 75.7–94.5%)", "Minimum ankle–brachial index (mABI) was extracted for 17,861 individuals with ABI measurements available in MVP. As expected, we observed a median mABI of less than 0.9 for PAD cases and approximately 1 for PAD controls across all three ethnic groups"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16135}
-{"validations": ["Validation against known SNPs related to NAFLD - Trans-ethnic meta-analysis replicated associations with previously reported genetic variants in all but LYPLAL1 and GCKR loci without attenuation when adjusted for metabolic risk factors and alcohol consumption. - At the previously reported LYPLAL1 locus, the established genetic variant did not appear to be associated with NAFLD, however the regional association plot showed a significant association with NAFLD 279kb downstream. Validation against liver biopsy and ultrasound - Positive predictive value 0.89 and 0.84 for liver biopsy and abdominal imaging, respectively (inter-rater reliability (Cohen’s kappa = 0.98)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 16151}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16145}
-{"validations": ["Divided data into training and validation datasets and also compared findings to expected associations. We modelled the system of relationships underlying the way in which the diet, lifestyle, and demographic components of the overall exposome shapes the cardiometabolic risk profile. We used multiple normal regression to examine the combined effects of exposure factors on the clinical factors representing cardiometabolic health. The model generated in the training dataset replicated expected associations in the validation dataset."], "methods_used": ["Other"], "phenotype_id": 15996}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16285}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16466}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16467}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16468}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16469}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16470}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16471}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16472}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16473}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16474}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16475}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16476}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16477}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15956}
-{"data_period": {"start": "2008-01-01", "end": "2017-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16267}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16341}
-{"validations": ["Compared accuracy and agreement between self reported ethnicity in CDW (without unknown) and algorithm derived ethnicity."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16342}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16343}
-{"validations": ["The Gold standard for alcohol dependence was based on the Composite International Diagnostic Interview—Substance Abuse Module (CIDI‐SAM) diagnosis of dependence. This questionnaire was administered by telephone to a sub-set of VACS participants. We chose to use a dependence-only reference measure instead of dependence/abuse because certain treatments and pharmacotherapies are indicated primarily for those who meet criteria for alcohol dependence. Various cutoffs for the AUDIT, AUDIT-C, and heavy episodic drinking were compared to the reference standards. Metrics below are based on AUDIT-C 3+ or heavy episodic drinking, please see manuscript for full list of performance metrics at various cutoffs."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16348}
-{"validations": ["Validated AUD against population-specific polymorphisms in ADH1B. Age-adjusted mean AUDIT-C (8+ vs. 0) was associated with lower odds of having the ADH1B minor allele than were AUD diagnostic codes."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16055}
-{"validations": ["Validated AUDIT-C trajectory against population-specific polymorphisms in ADH1B. Age-adjusted mean AUDIT-C (8+ vs. 0) was associated with lower odds of having the ADH1B minor allele than were AUD diagnostic codes."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16131}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16136}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15975}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16322}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15976}
-{"data_period": {"start": "2011-10-01", "end": "2017-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16798}
-{"data_period": {"start": "2001-01-01", "end": "2015-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16799}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15630}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16004}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16287}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16284}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16283}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16292}
-{"validations": ["500 patient charts reviewed by 5 clinicians. 25% of charts reviewed by 2 reviewers. Weighted kappa = 0.718-0.857."], "methods_used": ["Machine learning: Supervised"], "phenotype_id": 16334}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15979}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15998}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16288}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16293}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16286}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16282}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16280}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16281}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16291}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16279}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16290}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 16278}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 16277}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16273}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16275}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16274}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16276}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16272}
-{"validations": ["COVID positive patients were identified for chart review. Among this cohort we sampled patients based on two approaches i) with a U09.9 code and ii) without a U09.9 code but with a new onset PASC related ICD code, which allows us to assess the performance of the U09.9 code. To operationalize the long COVID definition based on health agency guidelines, we grouped symptoms into a “core” cluster of 11 commonly reported symptoms among long COVID patients and an extended cluster, that captured all other symptoms by disease domain. (Maripuri et al 2023). Patients having at least 2 symptoms persisting for >=60 days that were new onset after their COVID infection, with at least one symptom in the core cluster, were labeled as having long COVID per chart review. The three institutions have been anonymized to provide an unbiased interpretation of the results. Health System 1 Results", "COVID positive patients were identified for chart review. Among this cohort we sampled patients based on two approaches i) with a U09.9 code and ii) without a U09.9 code but with a new onset PASC related ICD code, which allows us to assess the performance of the U09.9 code. To operationalize the long COVID definition based on health agency guidelines, we grouped symptoms into a “core” cluster of 11 commonly reported symptoms among long COVID patients and an extended cluster, that captured all other symptoms by disease domain. (Maripuri et al 2023). Patients having at least 2 symptoms persisting for >=60 days that were new onset after their COVID infection, with at least one symptom in the core cluster, were labeled as having long COVID per chart review. The three institutions have been anonymized to provide an unbiased interpretation of the results. Health System 2 Results", "COVID positive patients were identified for chart review. Among this cohort we sampled patients based on two approaches i) with a U09.9 code and ii) without a U09.9 code but with a new onset PASC related ICD code, which allows us to assess the performance of the U09.9 code. To operationalize the long COVID definition based on health agency guidelines, we grouped symptoms into a “core” cluster of 11 commonly reported symptoms among long COVID patients and an extended cluster, that captured all other symptoms by disease domain. (Maripuri et al 2023). Patients having at least 2 symptoms persisting for >=60 days that were new onset after their COVID infection, with at least one symptom in the core cluster, were labeled as having long COVID per chart review. The three institutions have been anonymized to provide an unbiased interpretation of the results. Health System 3 Results"], "data_period": {"start": "2020-03-01", "end": "2021-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16206}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16289}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16271}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 16268}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16270}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16269}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 16074}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 16076}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 16936}
-{"validations": ["We have performed a chart review of n=39 “difficult cases”. That is, MVP participants with either a) 1 ICD code for either MCI, AD, or dementia, or b) subjects with low to moderate AD case probability according to the Multimodal Automated Phenotype (MAP) algorithm (Liao et al. Am Med Inform Assoc, 2019). These were reviewed in tandem by Drs. Hauger and Meritt of the AD/MCI working group and classified as “Likely not”, “Possible”, or “Likely” cases of MCI, AD, and dementia. Chart review results were compared to the classifications according to the MAP algorithm and according to our ICD-code based definitions of MCI, AD, ADRD, and dementia (Table 2). The performance of the ICD code set in shown in \"Algorithm Performance Measures\". The authors also evaluated the suitability of our ICD code based phenotypes in genetic studies by testing their association with the APOE E4 isoform (the strongest AD genetic risk factor) in European-descent MVP subjects (Table 3)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16104}
-{"validations": ["We have performed a chart review of n=39 “difficult cases”. That is, MVP participants with either a) 1 ICD code for either MCI, AD, or dementia, or b) subjects with low to moderate AD case probability according to the Multimodal Automated Phenotype (MAP) algorithm (Liao et al. Am Med Inform Assoc, 2019). These were reviewed in tandem by Drs. Hauger and Meritt of the AD/MCI working group and classified as “Likely not”, “Possible”, or “Likely” cases of MCI, AD, and dementia. Chart review results were compared to the classifications according to the MAP algorithm and according to our ICD-code based definitions of MCI, AD, ADRD, and dementia (Table 2). The performance of the ICD code set in shown in \"Algorithm Performance Measures\". The authors also evaluated the suitability of our ICD code based phenotypes in genetic studies by testing their association with the APOE E4 isoform (the strongest AD genetic risk factor) in European-descent MVP subjects (Table 3)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16109}
-{"validations": ["The VA-FI-10 deficits showed stability before and after the transition to ICD-10 in 2015 and maintained strong associations with mortality. Patients classified as frail (VA-FI > 0.2) consistently had a hazard of death more than 2 times higher than non frail patients (VA-FI ≤ 0.1). See manuscript for more details (PMID: 33693638)"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16148}
-{"validations": ["Leave-one-out cross-validation was used to evaluate the proposed TBI-PheCAP algorithm. TBI-PheCAP performance was also compared to existing TBI algorithms and phenotyping methods."], "data_period": {"start": "2002-01-01", "end": "2018-09-30"}, "methods_used": ["Machine learning: Semi-Supervised"], "phenotype_id": 15994}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15631}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15632}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15633}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15634}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 15635}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15636}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15637}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15638}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15639}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15640}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15850}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15851}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15852}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15855}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15654}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15655}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15658}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15659}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15660}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15661}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15662}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15664}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15665}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15666}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15667}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15668}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15669}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15670}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15671}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15672}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15673}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15674}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15675}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15676}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15974}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15677}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15678}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15679}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15680}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15681}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15682}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15683}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15684}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15685}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15686}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15687}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15688}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15689}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15690}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15691}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15692}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15693}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15694}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15695}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15696}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15697}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15698}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15699}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15700}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15701}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15702}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15703}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15704}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15705}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15706}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15707}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15708}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15709}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15710}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15856}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15857}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15858}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15859}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15860}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15861}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15862}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15863}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15711}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15712}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15713}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15714}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15715}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15716}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15717}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15718}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15719}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15720}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15721}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15722}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15723}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15724}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15725}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15726}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15727}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15728}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15729}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15730}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15731}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15732}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15733}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15734}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15735}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15736}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15737}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15738}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15739}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15740}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15741}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15742}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15743}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15744}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15745}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15746}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15747}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15748}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15749}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 15750}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15751}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15765}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15766}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15767}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15771}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15781}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15782}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 15783}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 15953}
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-{"validations": ["To assess the accuracy of our algorithm to traditional methods, we compared the algorithm's results to the documentation of RA in CDW. We used sensitivity, positive predictive value, and accuracy to describe and quantify agreement between the two sources of information.", "We manually reviewed a random sample of 250 cases to refine the algorithm's accuracy. If the overall accuracy of the algorithm in the sample was <95%, then we repeated the process."], "data_period": {"start": "2017-01-01", "end": "2022-12-31"}, "methods_used": ["Other", "Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17977}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17450}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17451}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17452}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17453}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17454}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17455}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17456}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17457}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17458}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17459}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17460}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17461}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17462}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17463}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17473}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17474}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17475}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17476}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17477}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17478}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17464}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17465}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17466}
-{"validations": ["We conducted an evaluation of the administrative algorithm's performance, assessing its accuracy against a comprehensive review of medical records. Assessment involved agreement between the algorithm and medical record review classification and corresponding kappa statistics. This Algorithm had the best agreement with medical record review (κ = 0.74; κ = 0.70 relaxed ILD definition), indicating substantial agreement. Performance metrics for this algorithm were sensitivity 73.2% (65.4% relaxed ILD definition), specificity 98.2% (98.5% relaxed ILD definition), and PPV 78.5% (82.4% relaxed ILD definition)."], "data_period": {"start": "1998-12-31", "end": "2018-08-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17590}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 18221}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18219}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18218}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18210}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18207}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18217}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18203}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18202}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18215}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18211}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 18208}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18205}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17467}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17468}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17469}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17470}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17471}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18214}
-{"validations": ["NLP-derived FVC values were compared to values recorded directly from PFT equipment available on a subset of patients. Out of 2610 date-matched Forced Vital Capacity (FVC) values obtained from both Natural Language Processing (NLP) and PFT equipment, 95.8% of the values fell within a 5% predicted range. The mean difference was 0.09% (standard deviation 5.9%), indicating a strong correlation between the values (r = 0.94, p < 0.001) and a precision of 0.87 (95% CI 0.86, 0.88). Notably, NLP captured longitudinal FVC values for more patients (n = 3069) compared to PFT equipment (n = 1164)."], "data_period": {"start": "1999-12-31", "end": "2020-12-30"}, "methods_used": ["Machine learning: Supervised"], "phenotype_id": 17607}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18213}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18212}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18201}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17472}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17514}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17515}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17516}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17517}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17518}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17519}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17520}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17521}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17522}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17523}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17524}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17525}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17526}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17527}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17528}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17479}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17480}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17481}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17482}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17483}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17484}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17485}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17486}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17487}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17488}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17489}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17490}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17491}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17492}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17493}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17494}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17495}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17496}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17497}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17498}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17499}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17500}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17501}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17502}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17503}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17504}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17505}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17506}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17507}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17508}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17509}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17510}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17511}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17512}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 17513}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 18438}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18432}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 18433}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17529}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17530}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17531}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17532}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17533}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17534}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17535}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17536}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17537}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17538}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17539}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17540}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17541}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17542}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17543}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 17544}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17545}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17546}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17547}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17548}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17549}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17550}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17551}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17552}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 17553}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 17554}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17555}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17556}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17557}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17558}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17559}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17560}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17561}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17562}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17563}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17564}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17565}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17566}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17567}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17568}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17569}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17570}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17571}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17572}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17573}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17574}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17575}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17576}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17577}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17578}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17579}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17580}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17581}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17582}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17583}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17584}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17585}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17586}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17587}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18484}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18435}
-{"data_period": {"start": "2000-01-01", "end": "2020-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 29575}
-{"data_period": {"start": "2000-01-01", "end": "2020-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29576}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29581}
-{"methods_used": ["Machine learning: Semi-Supervised", "Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29582}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29583}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29584}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29585}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29586}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29587}
-{"data_period": {"start": "2015-08-01", "end": "2023-08-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29105}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18439}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29522}
-{"data_period": {"start": "1986-01-01", "end": "2018-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 29588}
-{"data_period": {"start": "1986-01-01", "end": "2018-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 29589}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17133}
-{"validations": ["Performance or semi-supervised model against the WHO-1 Long COVID chart review definition during the post-ICD U09.9 period. See publication for a comparison of validation metrics by phenotyping method at VHA and at UPMC.", "Performance or semi-supervised model against the WHO-1 Long COVID chart review definition during the pre-ICD U09.9 period. See publication for a comparison of validation metrics by phenotyping method at VHA and at UPMC."], "data_period": {"start": "2020-03-01", "end": "2022-09-30"}, "methods_used": ["Machine learning: Semi-Supervised"], "phenotype_id": 29120}
-{"adjudication_method": "Testosterone (masculinizing hormone therapy) , estrogen, estradiol and spironolactone (feminizing hormone therapy) available in national VA data were reviewed by the study team endocrinologist. The objective of this adjudication was to exclude any medications or lower doses of some medications, which can be used to treat conditions in cisgender (non- transgender) people.", "adjudication_performed": true, "validations": ["Algorithm for ascertaining gender affirming hormone therapy was validated using chart reviews by clinicians on the team (Wolfe et al., 2021; https://academic.oup.com/aje/article/190/9/1928/6222074#google_vignette). This gender affirming hormone algorithm has been replicated and adapted in several non-VA datasets, including Optum Labs, and MarketScan claims data."], "data_period": {"start": "2005-12-31", "end": "2018-12-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 29187}
-{"validations": ["A validation cohort was created to conduct manual chart review of each case and establish if the individual had a confirmed genetic diagnosis, i.e. a finding of at least one variant in a known disease-related gene that was classified as (likely) pathogenic according to American College of Medical Genetics and Genomics (ACMG) criteria.20. The age at genetic testing or diagnosis of a genetic disorder was not restricted to account for potential diagnostic delays. This strict subset of cases was matched to an independent set of controls that had ≥ 1 order for any genetic testing and a negative match on our custom NLP algorithm."], "data_period": {"start": "1998-01-01", "end": "2023-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29635}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29639}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29640}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29641}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29642}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29648}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29649}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29650}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29651}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29652}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29653}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29654}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29655}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29656}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29657}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29658}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29659}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29636}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 29637}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29669}
-{"validations": ["Vanderbilt University Cases: 0 Controls: 0 (Case, Control) Uploaded: 03/22/2012"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 29190}
-{"validations": ["The clinicians employed in double-annotated chart review are experienced in the clinical practice of ASD diagnosis (at BCH, one developmental-behavioral pediatrician (JB) and one psychologist (LWW); at CCHMC, one psychologist (NB), one nurse practitioner (JR) and one developmental-behavioral pediatrician (PMC)). There are four labels in the gold standard ASD diagnoses: “yes” indicates an ASD case; “no” label is a non-case; “maybe” is an uncertain case, some evidence for case; “unknown” is an indeterminate status, with insufficient information to make a decision relative to case status."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29194}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29195}
-{"validations": ["For each site participating in the phenotype validation process, 25-50 cases and 25-50 controls identified by the automated phenotyping algorithm were randomly selected."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29197}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29545}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29643}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29644}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29645}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29646}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29647}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18206}
-{"validations": ["Group Health Cooperative Cases: 0 Controls: 0 (Case, Control) Uploaded: 06/06/2012"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29191}
-{"validations": ["Vanderbilt University Cases: 0 Controls: 0 (Case, Control) Uploaded: 03/22/2012"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29192}
-{"validations": ["Columbia University Cases: 132 Controls: 29 (Case, Control) Uploaded: 02/02/2018"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29193}
-{"validations": ["All electronically identified potential surgical cataract cases were manually reviewed by a trained research coordinator who verified the presence or absence of a cataract by using the medical chart and supporting documentation. A board-certified ophthalmologist resolved questions surrounding classifications. In addition, stratified random samples were selected to validate potential cases with diagnoses but no surgery, potential controls, and each cataract attribute for the multi-modal approach. See manuscript for validation metrics by algorithm approach."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 29196}
-{"validations": ["Cincinnati Children's Hospital Medical Center Cases: 15 Controls: 20 (Case, Control) Uploaded: 12/17/2014"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 29198}
-{"data_period": {"start": "2008-01-01", "end": "2017-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29199}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29200}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17865}
-{"validations": ["We randomly selected 100 individuals identified by algorithm 1 (meeting ≥ 1 of 3 criteria) for direct medical record review. Of those, 63 were also captured by algorithm 2 (meeting ≥ 2 of 3 criteria). VHA EHR data were reviewed independently by two gastroenterologists (CM and LW) and abstracted into a VHA Research Electronic Data Capture (REDCap) database. Each reviewer determined whether EHR data were consistent with a diagnosis of PDAC or an alternative diagnosis such as a benign mass, pancreatic neuroendocrine tumor, or metastasis from a distinct primary cancer. In cases of disagreement between reviewers, a third reviewer (YXY) reviewed the EHR to adjudicate the discrepancy. The NPV was calculated in 50 randomly selected individuals who died while hospitalized, did not meet the criteria for either case-finding algorithm, had a measured alkaline phosphatase level between the 25 and 75th percentiles of individuals identified by algorithm 2 to have possible pancreatic cancer."], "data_period": {"start": "2002-01-01", "end": "2023-04-24"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 18463}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18464}
-{"validations": ["From the phenotyping cohort of 100,000 Veterans, an additional n=100 Black Veterans were sampled to validate performance in this sub-population. This sample was named the \"Black Veteran validation dataset\". Performance of PheCAP was evaluated with the cutoff value corresponding to PPV=0.90 in the \"all race dataset\".", "From the phenotyping cohort of 100,000 Veterans, we randomly sampled 303 Veterans for chart review. This sample was named the \"all race dataset\". Using leave one out cross validation, the performance of the PheCAP algorithm was validated using a cutoff threshold corresponding to PPV=0.90."], "data_period": {"start": "2002-12-30", "end": "2019-12-30"}, "methods_used": ["Machine learning: Semi-Supervised"], "related_diseases": ["Cardiovascular"], "phenotype_id": 17877}
-{"validations": ["Chart reviews were conducted to ensure the data from CDW matched the patient's electronic dental record until 100% agreement was obtained."], "data_period": {"start": "2022-05-01", "end": "2024-02-28"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 18604}
-{"data_period": {"start": "2007-01-01", "end": "2015-01-01"}, "methods_used": ["Machine learning: Other machine learning approach"], "phenotype_id": 18647}
-{"data_period": {"start": "2002-01-01", "end": "2020-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18649}
-{"data_period": {"start": "2002-01-01", "end": "2020-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18650}
-{"data_period": {"start": "2002-01-01", "end": "2020-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18651}
-{"validations": ["In the publications referenced we compared electronic health record data to survey data and to biomarker data. https://doi.org/10.1093/ntr/ntr206 https://doi.org/10.1093/jamiaopen/ooac040 \"The Veterans Health Administration (VHA) changed the questions used to screen for tobacco use/smoking at routine clinic visits in October 2018. The tobacco use/smoking data from clinic visits prior to October 2018 was shown to agree well with confidentially self-reported cigarette smoking survey data, and the new questions beginning in October 2018 should result in even better agreement.\""], "data_period": {"start": "1999-10-01", "end": "2019-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18838}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18877}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18878}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18879}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18880}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18881}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18886}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18882}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18883}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18891}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18892}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18893}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18894}
-{"validations": ["Validated by subject matter experts and clinical field staff"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18895}
-{"validations": ["Validated by subject matter experts and clinical field staff"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18896}
-{"validations": ["Validated by subject matter experts and clinical field staff"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18897}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18898}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18899}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18900}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18901}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18902}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18903}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18904}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18905}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18906}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18907}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18908}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18909}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18910}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18911}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18912}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18913}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18914}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18915}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18916}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18917}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18918}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18919}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18920}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18921}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18922}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18923}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 18924}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18925}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18926}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18927}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18930}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18931}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18932}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18933}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18934}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18935}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18936}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18937}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18938}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18939}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18940}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18941}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18942}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18943}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18944}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18945}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18946}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18947}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18948}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18949}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18950}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18951}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18952}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18953}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18954}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18955}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18956}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18957}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18958}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18959}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18960}
-{"validations": ["Validated by subject matter experts and clinical field staff."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18961}
-{"data_period": {"start": "2018-10-01", "end": "2024-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18969}
-{"data_period": {"start": "2018-10-01", "end": "2024-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18970}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18973}
-{"data_period": {"start": "2016-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18974}
-{"data_period": {"start": "2016-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18975}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18976}
-{"data_period": {"start": "2020-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18977}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18978}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18979}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18980}
-{"data_period": {"start": "2016-01-03", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18981}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18982}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18983}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18984}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18985}
-{"data_period": {"start": "2016-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18986}
-{"data_period": {"start": "1997-01-01", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18987}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18988}
-{"data_period": {"start": "2016-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18989}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18990}
-{"data_period": {"start": "2021-01-01", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18991}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18992}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18993}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18994}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18995}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18996}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18997}
-{"data_period": {"start": "2019-01-04", "end": "2021-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 18998}
-{"data_period": {"start": "2018-10-01", "end": "2024-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 19003}
-{"validations": ["Chart review of potential cancer cases (identified by claims, cancer registry, and text string search)"], "data_period": {"start": "1996-10-01", "end": "2015-09-29"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 19005}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 19014}
-{"methods_used": ["Other"], "phenotype_id": 19018}
-{"data_period": {"start": "2016-10-01", "end": "2023-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 19019}
-{"validations": ["Cincinnati Children's Hospital Medical Center Cases: 0 Controls: 0 (Case, Control) Uploaded: 12/10/2018"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29201}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29202}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29638}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29203}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29204}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29205}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 29206}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 29519}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29207}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29546}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29547}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29548}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29208}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29211}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29212}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29213}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29214}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 29550}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29554}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29555}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18466}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 29209}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29210}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29238}
-{"data_period": {"start": "2004-01-01", "end": "2013-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29215}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29216}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 29217}
-{"data_period": {"start": "2005-01-01", "end": "2021-12-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18472}
-{"data_period": {"start": "2005-01-01", "end": "2021-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18473}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29218}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29553}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 18465}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29219}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 29221}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29220}
-{"validations": ["Manual review to confirm patients underwent exercise-stress test. In conclusion, the PPV for pharmacologic stress test codes is 114 / 117 = 0.98. These codes can accurately identify patients who underwent pharmacologic stress test."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29227}
-{"validations": ["CHOP Cases: 0 Controls: 0 (Case, Control) Uploaded: 04/28/2014"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 29228}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29229}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29232}
-{"validations": ["GH/UW Cases: 25 Controls: 25 (Case, Control) Uploaded: 08/04/2016"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29233}
-{"validations": ["\"CHOP Cases: 0 Controls: 0 (Case, Control) Uploaded: 05/31/2013\""], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29234}
-{"validations": ["Two physicians not associated with algorithm development reviewed algorithm results with access to the entire de-identified medical records of the patients. The results of the manual classification were then used to improve the algorithms, and the procedure was iterated until the positive predictive value reached the pre-designated target of ≥95% for a random selection of 100 subjects. In each iteration, the physicians reviewed a different set of 100 randomly selected subjects."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29236}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29237}
-{"data_period": {"start": "2005-01-01", "end": "2021-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18471}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29222}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29556}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29558}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29559}
-{"validations": ["Breast Cancer_Columbia Columbia University Cases: 87 Controls: 79 (Case, Control) Uploaded: 10/25/2018"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29230}
-{"validations": ["CHOP Cases: 0 Controls: 0 (Case, Control) Uploaded: 01/21/2015"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29231}
-{"validations": ["To validate the performance of our CKD detection and staging algorithm, we determined the overall and stage-specific positive predictive values (PPV) of the algorithmic diagnoses by performing 451 blinded manual chart reviews of algorithm-derived diagnostic labels across three major US medical centers. The overall diagnostic PPV was 95% (range 83–99%) for CKD cases and 97% (range 95–100%) for healthy controls."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29235}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29239}
-{"validations": ["Geisinger Cases: 0 Controls: 0 (Case, Control) Uploaded: 06/20/2012"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29240}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29168}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29557}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29243}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29560}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 29561}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 18444}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 18445}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 18446}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 18443}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 18442}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18448}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 18436}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18428}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18485}
-{"data_period": {"start": "2011-01-13", "end": "2024-07-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 29459}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 18447}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18440}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18486}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 18434}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16996}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16997}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16998}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 16999}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17000}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17001}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17002}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17003}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17004}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17005}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 17006}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 17007}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dental"], "phenotype_id": 17008}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17009}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17010}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17011}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17012}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17013}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17014}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17015}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17016}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17017}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17018}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17019}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17020}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17021}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17022}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17023}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17024}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17025}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17026}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17027}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17028}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17029}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17030}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17031}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17032}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17033}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17034}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17035}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17036}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17037}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17038}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17039}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17040}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17041}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17042}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17043}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17044}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17045}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17046}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17047}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17048}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17049}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17050}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17051}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17052}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17053}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17054}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17055}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17056}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17057}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17058}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17059}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17060}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17061}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17062}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17063}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17064}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17065}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17066}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17067}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17068}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17069}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17070}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17071}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17072}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17073}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17074}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17075}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17076}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17077}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17078}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17079}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17080}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17081}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17082}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17083}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17084}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17085}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17086}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17087}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17088}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17089}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17090}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17091}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17092}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17093}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17094}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17095}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17096}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17097}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17098}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 17099}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17100}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17101}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17102}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17103}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17104}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 17105}
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-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30613}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30614}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30615}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30616}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30617}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30618}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30619}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30620}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30621}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30622}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30623}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30624}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30625}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30626}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30627}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30628}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 30629}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30630}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30631}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30632}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30633}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30634}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30635}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30636}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30638}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30639}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30640}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30641}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30642}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30643}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30644}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30645}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30646}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30647}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30648}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30649}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30650}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30651}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30652}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30653}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30654}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30655}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30656}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30657}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30658}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30659}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30660}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30661}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30662}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30663}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30664}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 30665}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30666}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30667}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30668}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30669}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30670}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30671}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30672}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30673}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30674}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30675}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30676}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30678}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30689}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30693}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30694}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30695}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30696}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30697}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30698}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30702}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30703}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30704}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30706}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30707}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30715}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30718}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30719}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30720}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30722}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30723}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30726}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 30730}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30738}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30739}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30746}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30750}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30752}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30753}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30754}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30755}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30757}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30758}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30764}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30768}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30769}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30778}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30780}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30781}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30789}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30804}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30805}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30806}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31128}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31129}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31169}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31174}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31182}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31183}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31184}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31185}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31192}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31193}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31194}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31195}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31199}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31200}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31204}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31205}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31216}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31220}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31221}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31224}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31225}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31226}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31227}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31228}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31229}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31230}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31238}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31245}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30677}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30679}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30681}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30682}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30683}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30684}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30685}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30687}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30690}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30691}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30692}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30700}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30680}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30686}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30688}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30699}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30701}
-{"validations": ["Manual chart review was conducted for case and control charts (250 each, randomly selected) using a phenotype manual to facilitate chart review. Two reviewers were assigned to assess the presence or absence of T2DM in Text Integration Utilities (TIU) notes extracted from each chart. Discrepancies were resolved during weekly SME meetings and these discussions were used to further refine the approach for identifying the presence of absence of the phenotype."], "data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Machine learning: Supervised", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31080}
-{"validations": ["Manual chart review was conducted for case and control charts (250 each, randomly selected) using a phenotype manual to facilitate chart review. Two reviewers were assigned to assess the presence or absence of hypertension in Text Integration Utilities (TIU) notes extracted from each chart. Discrepancies were resolved during weekly SME meetings and these discussions were used to further refine the approach for identifying the presence of absence of the phenotype."], "data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Machine learning: Supervised", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31081}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31084}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31085}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31089}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31093}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31094}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31095}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31096}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31098}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31101}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31104}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31105}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31106}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31107}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31108}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31115}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31116}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31117}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31118}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31119}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31120}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31122}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31124}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31140}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31141}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31142}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31143}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31144}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31145}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31146}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31147}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31157}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30705}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30708}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30709}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 30710}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30711}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30712}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30713}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30714}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30716}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30717}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 30721}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 30724}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30725}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 30727}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30728}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30729}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30731}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30732}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30733}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30734}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30735}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30736}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30737}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30740}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30741}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 30742}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30743}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30744}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30745}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30747}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30748}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30751}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30756}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30759}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30760}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30761}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30762}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30763}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30765}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30766}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 30767}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30770}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30771}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 30772}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30773}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30774}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30775}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30776}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30777}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30779}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30782}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30783}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30784}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30785}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30786}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30787}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30788}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30790}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30791}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30792}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30793}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30794}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30795}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30796}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30797}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30798}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30802}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30803}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 30807}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 30808}
-{"validations": ["Manual chart review was conducted for case and control charts (250 each, randomly selected) using a phenotype manual to facilitate chart review. Two reviewers were assigned to assess the presence or absence of heart failure in Text Integration Utilities (TIU) notes extracted from each chart. Discrepancies were resolved during weekly SME meetings and these discussions were used to further refine the approach for identifying the presence of absence of the phenotype."], "data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Machine learning: Supervised", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31079}
-{"validations": ["Manual chart review was conducted for case and control charts (250 each, randomly selected) using a phenotype manual to facilitate chart review. Two reviewers were assigned to assess the presence or absence of stroke in Text Integration Utilities (TIU) notes extracted from each chart. Discrepancies were resolved during weekly SME meetings and these discussions were used to further refine the approach for identifying the presence of absence of the phenotype."], "data_period": {"start": "2000-01-01", "end": "2022-12-31"}, "methods_used": ["Machine learning: Supervised", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31082}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31083}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31086}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31209}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31223}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31087}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31088}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31090}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31091}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31092}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31097}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31099}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31100}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31102}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31103}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31109}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31110}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31111}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31112}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31113}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31114}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31121}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31123}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31125}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31126}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31127}
-{"data_period": {"start": "2012-10-01", "end": "2023-09-30"}, "methods_used": ["Other", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Endocrine/Metabolic"], "phenotype_id": 30749}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31133}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31134}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31135}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31136}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31137}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31138}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31139}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31148}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31149}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31150}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31151}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31152}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31153}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31154}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31155}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31156}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31158}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31159}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31160}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31161}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 31162}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 31163}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 31164}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 31165}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 31166}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 31167}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31171}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31172}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31173}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31175}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31176}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31177}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31178}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31179}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31180}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31181}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31186}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31187}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31188}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31189}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31190}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31191}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31196}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31197}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31198}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31201}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31202}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31203}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31206}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31207}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31208}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31222}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31210}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31211}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31212}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31213}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31214}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31215}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31217}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31218}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31219}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31243}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31244}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31231}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31232}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31233}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31234}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31235}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31236}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31237}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31239}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31240}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31241}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31242}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31246}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31248}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31251}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31247}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31249}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31250}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31252}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31253}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31254}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31255}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31256}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31257}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31258}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31259}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31260}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31261}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31262}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31263}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31264}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Endocrine/Metabolic"], "phenotype_id": 31271}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31272}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31273}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31274}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31290}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31291}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31293}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31311}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31312}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31314}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31315}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31317}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31265}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31266}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31267}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31268}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31269}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31270}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31275}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31276}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31277}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31278}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31279}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31280}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31281}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31282}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31283}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31284}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31285}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31286}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31292}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31287}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31288}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31289}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31295}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31296}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31297}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31300}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31301}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31589}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31590}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31591}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31294}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31298}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31299}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31302}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31303}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31304}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31305}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31306}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31307}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31308}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31309}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31310}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31313}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31318}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31319}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31320}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31321}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31322}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31323}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31324}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31576}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31577}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31578}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31579}
-{"validations": ["The \"gold standard\" for validating a public health phenotype is its ability to predict real-world health outcomes. Singh validated the ADI by linking it to National Vital Statistics (1969–1998): Mortality Gradients: The study found a direct, linear relationship between the ADI score and mortality. Residents of the \"Most Deprived\" quintile had significantly higher death rates than those in the \"Least Deprived\" quintile. Correlation Coefficients: The ADI showed strong correlations with specific health indicators: All-cause mortality: $r = 0.58$ Infant mortality: $r = 0.48$ Heart Disease: $r = 0.45$ Sensitivity over Time: Singh validated the index across three decades of Census data (1970, 1980, 1990), proving that the algorithm remained a valid predictor of health even as the US economy and demographics shifted.", "The validity of the 1990 deprivation index was tested by comparing factor loadings for the same set of 17 indicators computed at the census tract, zip code, and county levels. The factor loadings for the 3 geographic levels were generally similar in magnitude and relative importance. The percentages of explained variance and reliability coefficients were almost identical for the 1990 census tract and county indices. Internal Consistency: The index achieved a Cronbach’s alpha of 0.94. In psychometrics and statistics, any value above 0.90 is considered \"excellent,\" meaning the 17 variables are highly interrelated. Factor Loading: Principal Component Analysis (PCA) showed that all 17 variables loaded strongly onto a single factor. Loadings ranged from 0.45 to 0.92, confirming that \"Area Deprivation\" was a statistically sound, unified construct."], "methods_used": ["Other"], "phenotype_id": 31586}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31587}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31588}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31592}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31593}
-{"data_period": {"start": "2012-01-01", "end": "2022-09-30"}, "methods_used": ["Machine learning: Supervised", "Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31629}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31630}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31631}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31632}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31633}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31634}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31635}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31636}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31637}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31638}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31639}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31640}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31641}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31642}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31643}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31644}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31645}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31646}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31649}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31647}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31648}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31656}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31659}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31660}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31662}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31666}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31667}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31669}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31670}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31671}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31678}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31679}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31680}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31681}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31685}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31686}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31687}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31688}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31689}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31690}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31691}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31692}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31693}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31694}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31695}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31696}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31699}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31701}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31702}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31707}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31708}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31717}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31722}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31723}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31724}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31725}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31726}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31728}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31729}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31650}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31657}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31658}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31668}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31682}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31683}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31684}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31697}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31698}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31700}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31710}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31711}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31712}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31713}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31651}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31652}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31653}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31654}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31655}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31703}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31704}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31705}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31706}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31709}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31718}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31719}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31720}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31721}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31727}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31730}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31810}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31811}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31813}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31814}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31815}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31816}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31817}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31818}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31819}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31820}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31821}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31822}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Congenital Anomalies"], "phenotype_id": 31823}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31824}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31825}
-{"data_period": {"start": "2007-01-01", "end": "2016-03-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31826}
-{"data_period": {"start": "2011-01-01", "end": "2022-01-01"}, "methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 31827}
-{"data_period": {"start": "2011-01-01", "end": "2022-01-01"}, "methods_used": ["Machine learning: Unsupervised"], "phenotype_id": 31828}
-{"data_period": {"start": "2008-01-01", "end": "2023-07-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31829}
-{"validations": ["Validation of PA algorithm performance was evaluated via a chart review."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31830}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31831}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31832}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31833}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31834}
-{"validations": ["We reviewed the charts of 200 patients, independent of those assessed for diagnostic code selection, to calculate PPV at CUIMC. Hepatologists at VUMC and UPHS reviewed 20 charts for PPV calculation. Overall, 390 clinical charts were reviewed during algorithm development and validation."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31835}
-{"validations": ["Chart review was conducted on 239 patients - Cohort 1 (Incident Hypertension)"], "data_period": {"start": "2018-01-01", "end": "2023-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31836}
-{"validations": ["239 patients were chart reviewed for Cohort 1 (Incident Hypertension)"], "data_period": {"start": "2018-01-01", "end": "2023-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31837}
-{"validations": ["239 patients were chart reviewed for Cohort 1 (Incident Hypertension)"], "data_period": {"start": "2018-01-01", "end": "2023-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31838}
-{"validations": ["239 patients were chart reviewed for Cohort 1 (Incident Hypertension)"], "data_period": {"start": "2018-01-01", "end": "2023-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31839}
-{"validations": ["239 patients were chart reviewed for Cohort 1 (Incident Hypertension)"], "data_period": {"start": "2018-01-01", "end": "2023-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31840}
-{"validations": ["239 patients were chart reviewed for Cohort 1 (Incident Hypertension)"], "data_period": {"start": "2018-01-01", "end": "2023-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31841}
-{"validations": ["239 patients were chart reviewed for Cohort 1 (Incident Hypertension)"], "data_period": {"start": "2018-01-01", "end": "2023-01-01"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31842}
-{"validations": ["Complete charts minus identifiers for 103 Veterans were provided to this study by the MVP Data Core in two batches. The first batch (n=20) was a random selection of participants from three MAP algorithm AD probability bins: low AD probability (<=10%, n=7), medium AD probability (50–60%, n=7), and high AD probability (∼90%, n=6). The second batch (n=83) was a random selection of participants chosen to ensure that they had at least some level of evidence for mild cognitive impairment (MCI), AD, or dementia by requiring that the subject have exactly 1 ICD code for AD (n=29) regardless of the other types of codes, exactly 1 ICD code for MCI (n=26), or exactly 1 ICD code for any form of dementia (n=28). Our primary analysis contrasted those with “Not Likely” with “Possible” and “Likely” AD or dementia. Since it was not reasonable to evaluate the performance of an AD algorithm relative to a chart review for a broad dementia classification and vice versa, we contrasted the AD-centric algorit"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31843}
-{"validations": ["Complete charts minus identifiers for 103 Veterans were provided to this study by the MVP Data Core in two batches. The first batch (n=20) was a random selection of participants from three MAP algorithm AD probability bins: low AD probability (<=10%, n=7), medium AD probability (50–60%, n=7), and high AD probability (∼90%, n=6). The second batch (n=83) was a random selection of participants chosen to ensure that they had at least some level of evidence for mild cognitive impairment (MCI), AD, or dementia by requiring that the subject have exactly 1 ICD code for AD (n=29) regardless of the other types of codes, exactly 1 ICD code for MCI (n=26), or exactly 1 ICD code for any form of dementia (n=28). Our primary analysis contrasted those with “Not Likely” with “Possible” and “Likely” AD or dementia. Since it was not reasonable to evaluate the performance of an AD algorithm relative to a chart review for a broad dementia classification and vice versa, we contrasted the AD-centric algorit"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31844}
-{"validations": ["Complete charts minus identifiers for 103 Veterans were provided to this study by the MVP Data Core in two batches. The first batch (n=20) was a random selection of participants from three MAP algorithm AD probability bins: low AD probability (<=10%, n=7), medium AD probability (50–60%, n=7), and high AD probability (∼90%, n=6). The second batch (n=83) was a random selection of participants chosen to ensure that they had at least some level of evidence for mild cognitive impairment (MCI), AD, or dementia by requiring that the subject have exactly 1 ICD code for AD (n=29) regardless of the other types of codes, exactly 1 ICD code for MCI (n=26), or exactly 1 ICD code for any form of dementia (n=28). Our primary analysis contrasted those with “Not Likely” with “Possible” and “Likely” AD or dementia."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31845}
-{"validations": ["Complete charts minus identifiers for 103 Veterans were provided to this study by the MVP Data Core in two batches. The first batch (n=20) was a random selection of participants from three MAP algorithm AD probability bins: low AD probability (<=10%, n=7), medium AD probability (50–60%, n=7), and high AD probability (∼90%, n=6). The second batch (n=83) was a random selection of participants chosen to ensure that they had at least some level of evidence for mild cognitive impairment (MCI), AD, or dementia by requiring that the subject have exactly 1 ICD code for AD (n=29) regardless of the other types of codes, exactly 1 ICD code for MCI (n=26), or exactly 1 ICD code for any form of dementia (n=28). Our primary analysis contrasted those with “Not Likely” with “Possible” and “Likely” AD or dementia."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31846}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Machine learning: Supervised"], "phenotype_id": 31847}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31848}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Machine learning: Supervised"], "phenotype_id": 31849}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31850}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC).", "We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Machine learning: Supervised"], "phenotype_id": 31851}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31852}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Machine learning: Supervised"], "phenotype_id": 31853}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31854}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31856}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31870}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31875}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31876}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31880}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31882}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31916}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31919}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31921}
-{"validations": ["We followed a Delphi-like approach to develop the human-defined rule-based CP. For the ML classifier approach, we trained supervised ML (XGBoost) models using 78 features. Using surveys as the reference standard, we calculated sensitivity, specificity, positive predictive values, and area under the curve (AUC)."], "methods_used": ["Machine learning: Supervised"], "phenotype_id": 31855}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31860}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31865}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31867}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31868}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31869}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31877}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31878}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31879}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31891}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31892}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31894}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31897}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31898}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31901}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31902}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31907}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31911}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31857}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31812}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31866}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31871}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31872}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31873}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31874}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31881}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31883}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31884}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31885}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31886}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31887}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31888}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31889}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31890}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31893}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31895}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31896}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31899}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31900}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31903}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31904}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31905}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31906}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31908}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31909}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31910}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31912}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31913}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31914}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31915}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31918}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31920}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31922}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31923}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31924}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31925}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31926}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31927}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31928}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31929}
-{"validations": ["40 notes which were labelled as spinal cord stimulator placements were randomly sampled and reviewed by a clinician Co-I of the grant."], "data_period": {"start": "2016-01-01", "end": "2025-12-31"}, "methods_used": ["Other", "Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31931}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31932}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31933}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31934}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31935}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31936}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31937}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31938}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31939}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31940}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31941}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31942}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31943}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31944}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31945}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31946}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31947}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31948}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31949}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31950}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31951}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31952}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31953}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31954}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31955}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31956}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31957}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31958}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31959}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31960}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31961}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31962}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31963}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31964}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31965}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31966}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31967}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31968}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31969}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31970}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31971}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31972}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31973}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31974}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31975}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31976}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31977}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31978}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31983}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31986}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31987}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Congenital Anomalies"], "phenotype_id": 31989}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31995}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32001}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32002}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32006}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32014}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32015}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31979}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31984}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31985}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31988}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31994}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 32004}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32009}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32010}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 32011}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32012}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31980}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31981}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 31982}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31990}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31991}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31992}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31993}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31996}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31997}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 31998}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 31999}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32000}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32003}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 32008}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32013}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32007}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 32005}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 31917}
-{"data_period": {"start": "2022-01-01", "end": "2022-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 32078}
-{"data_period": {"start": "2022-01-01", "end": "2022-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 32079}
-{"data_period": {"start": "2019-09-01", "end": "2021-10-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology", "Endocrine/Metabolic"], "phenotype_id": 32081}
-{"data_period": {"start": "2019-09-01", "end": "2021-10-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology", "Endocrine/Metabolic"], "phenotype_id": 32082}
-{"data_period": {"start": "2019-09-01", "end": "2021-10-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology", "Endocrine/Metabolic"], "phenotype_id": 32083}
-{"data_period": {"start": "2019-09-01", "end": "2021-10-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology", "Endocrine/Metabolic"], "phenotype_id": 32084}
-{"data_period": {"start": "2019-09-01", "end": "2021-10-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology", "Endocrine/Metabolic"], "phenotype_id": 32085}
-{"data_period": {"start": "2019-09-01", "end": "2021-10-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology", "Endocrine/Metabolic"], "phenotype_id": 32086}
-{"validations": ["A random sample of 491 were selected for chart review, since these are important borderline cases where the phenotyping algorithm is more likely to result in misclassification errors. Presence or absence of VTE was confirmed by reviewing the entire patient EHR within ±6 months for any indication of an incident VTE at the phenotype(−) diagnostic encounter to identify cases not captured by the phenotyping algorithm. For example, a patient may have suffered a fatal PE prior to receiving chest imaging or may have received anticoagulant medications outside of the ±6-h window around the radiologist's review of imaging; both cases would be missed based on the current algorithm specifications. If there was no incident VTE, then the phenotype(−) diagnostic encounter was classified as a true negative. If an incident VTE was identified, then the encounter was determined to be a false negative."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 32087}
-{"data_period": {"start": "2002-01-01", "end": "2024-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32091}
-{"data_period": {"start": "2011-01-01", "end": "2022-09-30"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 32095}
-{"validations": ["Validation for performance of predicting MCI/ADRD chart diagnoses using logistic regression models using ICD Only, Med Only, Note Only, and ICD+Med+Note Input"], "data_period": {"start": "2012-01-03", "end": "2017-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32096}
-{"validations": ["Validation for performance of predicting MCI/ADRD chart diagnoses using logistic regression models using ICD Only, Med Only, Note Only, and ICD+Med+Note Input"], "data_period": {"start": "2012-01-03", "end": "2017-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32097}
-{"validations": ["Validation was for performance of predicting MCI/ADRD chart diagnoses using logistic regression models using ICD Only, Med Only, Note Only, and ICD+Med+Note imput"], "data_period": {"start": "2012-01-03", "end": "2017-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32098}
-{"validations": ["Validation was for performance of predicting MCI/ADRD chart diagnoses using logistic regression models using ICD Only, Med Only, Note Only, and ICD+Med+Note Input"], "data_period": {"start": "2012-01-03", "end": "2017-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32100}
-{"validations": ["Validation was for performance of predicting MCI/ADRD chart diagnoses using logistic regression models using ICD Only, Med Only, Note Only, and ICD+Med+Note Input"], "data_period": {"start": "2012-01-03", "end": "2017-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32099}
-{"validations": ["Validation was for performance of predicting MCI/ADRD chart diagnoses using logistic regression models using ICD Only, Med Only, Note Only, and ICD+Med+Note Input"], "data_period": {"start": "2012-01-03", "end": "2017-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32104}
-{"validations": ["Validation was for performance of predicting MCI/ADRD chart diagnoses using logistic regression models using ICD Only, Med Only, Note Only, and ICD+Med+Note Input"], "data_period": {"start": "2012-01-03", "end": "2017-11-03"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32105}
-{"validations": ["Three ophthalmologists (J.M.R., A.D.Z., and A.K.B. as adjudicator) manually reviewed 900 randomly selected Michigan patients. Each eye was categorized as having definite, possible, or no evidence of glaucoma, DR, and AMD. Raters were masked to project purpose and each other's assessments"], "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32106}
-{"validations": ["Three ophthalmologists (J.M.R., A.D.Z., and A.K.B. as adjudicator) manually reviewed 900 randomly selected Michigan patients. Each eye was categorized as having definite, possible, or no evidence of glaucoma, DR, and AMD. Raters were masked to project purpose and each other's assessments"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32107}
-{"validations": ["Three ophthalmologists (J.M.R., A.D.Z., and A.K.B. as adjudicator) manually reviewed 900 randomly selected Michigan patients. Each eye was categorized as having definite, possible, or no evidence of glaucoma, DR, and AMD. Raters were masked to project purpose and each other's assessments"], "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32108}
-{"validations": ["We identified 527 and 412 CD patients prescribed second line biologics following TNF antagonist exposure and met follow-up time requirements from MSHS and SPARC, respectively. We defined our cohorts using at least three IBD diagnoses, one IBD medication, and consistent coding on up to the five most recent encounters. These criteria yielded high precision, sensitivity, and specificity when defining the MSHS, CD and UC cohorts."], "data_period": {"start": "1990-01-01", "end": "2020-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 32111}
-{"data_period": {"start": "1990-01-01", "end": "2020-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 32112}
-{"data_period": {"start": "1990-01-01", "end": "2020-12-31"}, "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Gastrointestinal"], "phenotype_id": 32113}
-{"validations": ["A multidisciplinary team was established to map current care processes, describe specific pain points, and identify opportunities for targeted intervention. A multipronged intervention was designed to facilitate (1) patient identification for screening, (2) ordering of appropriate screening tests, (3) interpretation of screening test results, and (4) subsequent patient management."], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 32114}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular", "Endocrine/Metabolic"], "phenotype_id": 32115}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Dermatology"], "phenotype_id": 31170}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32016}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32017}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32018}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32019}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 30637}
-{"validations": ["Three ophthalmologists (J.M.R., A.D.Z., and A.K.B. as adjudicator) manually reviewed 900 randomly selected Michigan patients. Each eye was categorized as having definite, possible, or no evidence of glaucoma, DR, and AMD. Raters were masked to project purpose and each other's assessments"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32116}
-{"validations": ["Three ophthalmologists (J.M.R., A.D.Z., and A.K.B. as adjudicator) manually reviewed 900 randomly selected Michigan patients. Each eye was categorized as having definite, possible, or no evidence of glaucoma, DR, and AMD. Raters were masked to project purpose and each other's assessments"], "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32117}
-{"validations": ["Three ophthalmologists (J.M.R., A.D.Z., and A.K.B. as adjudicator) manually reviewed 900 randomly selected Michigan patients. Each eye was categorized as having definite, possible, or no evidence of glaucoma, DR, and AMD. Raters were masked to project purpose and each other's assessments"], "methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32118}
-{"data_period": {"start": "2013-01-01", "end": "2022-04-01"}, "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32119}
-{"data_period": {"start": "2013-01-01", "end": "2022-04-01"}, "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32121}
-{"data_period": {"start": "2013-01-01", "end": "2022-04-01"}, "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32122}
-{"data_period": {"start": "2013-01-01", "end": "2022-04-01"}, "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32123}
-{"data_period": {"start": "2013-01-01", "end": "2022-04-01"}, "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32124}
-{"data_period": {"start": "2013-01-01", "end": "2022-04-01"}, "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32120}
-{"data_period": {"start": "2013-01-01", "end": "2022-04-01"}, "methods_used": ["Machine learning: Supervised"], "related_diseases": ["ENT/ Ophthalmology"], "phenotype_id": 32134}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "phenotype_id": 32135}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Cardiovascular"], "phenotype_id": 32136}
-{"methods_used": ["Rules-Based (i.e., only structured data were used)"], "related_diseases": ["Endocrine/Metabolic"], "phenotype_id": 32137}