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33d7314 00746d1 33d7314 00746d1 33d7314 | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 | """Capability-based module registry for the TIDE evidence pipeline.
The pipeline is a set of *modules*. Each module declares a **capability**
(the kind of evidence it produces), an **eligibility** predicate (when it is
allowed to run for a given trial), and a **precedence** (how strongly it should
be preferred when several modules offer the same capability).
Selection is deliberately the module-level analogue of how the historical
comparator selects rows:
capability match -> eligibility gate -> precedence ranking -> fallback
For each capability, every registered provider is evaluated against the trial
profile. Ineligible providers are skipped with a recorded reason. Among the
eligible providers the highest-precedence one becomes the *primary* (its result
is what the report consumes); lower-precedence eligible providers are recorded
as *superseded* fallbacks. If no provider is eligible the capability is simply
absent — nothing is fabricated.
This is what lets a new module (e.g. Layla's validated publication-likelihood
model) drop in without touching the report or the UI: it registers as a
higher-precedence provider of the ``publication_outlook`` capability, and the
selector prefers it automatically the moment its eligibility predicate passes.
"""
from __future__ import annotations
import shutil
from collections import OrderedDict
from dataclasses import dataclass, field
from pathlib import Path
from typing import Any, Callable
from modules.pubtime import summarize_from_archive
from summarizer import summarize_with_llm, template_summary
# --------------------------------------------------------------------------- #
# Module contract
# --------------------------------------------------------------------------- #
# applies(profile, ctx) -> (eligible, reason)
Predicate = Callable[[dict[str, Any], dict[str, Any]], "tuple[bool, str]"]
# run(profile, ctx) -> {"status": str, "result": Any}
Runner = Callable[[dict[str, Any], dict[str, Any]], dict[str, Any]]
@dataclass(frozen=True)
class ModuleSpec:
name: str
capability: str
runtime: str # "python" | "r"
precedence: int
description: str
provenance: str
applies: Predicate
run: Runner
supported_domains: tuple[str, ...] = field(default=())
def _domain_gate(supported: tuple[str, ...]) -> Predicate:
def gate(profile: dict[str, Any], ctx: dict[str, Any]) -> tuple[bool, str]:
domain = profile.get("domain", "")
if not supported or domain in supported:
return True, "eligible"
return False, f"domain '{domain}' not covered by this module ({', '.join(supported)})."
return gate
def _always(_profile: dict[str, Any], _ctx: dict[str, Any]) -> tuple[bool, str]:
return True, "eligible"
# --------------------------------------------------------------------------- #
# Module implementations
# --------------------------------------------------------------------------- #
def _run_protocol_completeness(profile: dict[str, Any], _ctx: dict[str, Any]) -> dict[str, Any]:
sections = profile.get("protocol_sections", {})
total = sum(section["total"] for section in sections.values())
filled = sum(section["filled"] for section in sections.values())
ratio = round(filled / total, 3) if total else 0
weakest = sorted(
(
{
"section": name,
"filled": section["filled"],
"total": section["total"],
"missing": section["missing"],
}
for name, section in sections.items()
),
key=lambda item: (item["filled"] / item["total"]) if item["total"] else 0,
)
return {
"status": "ok",
"result": {
"filled_fields": filled,
"total_fields": total,
"completion_ratio": ratio,
"weakest_sections": weakest[:3],
},
}
def _run_historical_comparator(profile: dict[str, Any], ctx: dict[str, Any]) -> dict[str, Any]:
result = summarize_from_archive(profile, ctx["project_root"])
return {"status": "ok", "result": result}
def _run_comparator_base_rate(profile: dict[str, Any], ctx: dict[str, Any]) -> dict[str, Any]:
"""Empirical publication outlook, derived from the matched historical cohort.
This is an honest base rate ("of trials like yours, X% published"), not a
validated per-trial prediction. The predictive-model slot below is reserved
for a model that produces a true per-trial probability.
"""
evidence = ctx["capabilities"].get("historical_comparator") or {}
summary = evidence.get("summary", {})
return {
"status": "ok",
"result": {
"publication_likelihood": summary.get("publication_rate"),
"results_reporting_likelihood": summary.get("results_reported_rate"),
"basis_rows": evidence.get("used_rows"),
"match_strategy": evidence.get("match_strategy"),
"model_type": "empirical_base_rate",
"provenance_label": "Historical comparator",
"provenance_detail": (
"Publication rate among matched historical trials in the PubTime dataset. "
"This is an empirical base rate, not a validated per-trial prediction."
),
"predictive_model": {
"status": "reserved",
"reason": (
"Layla's validated publication-likelihood model can register as a "
"higher-precedence provider of the 'publication_outlook' capability; "
"the selector will then prefer it automatically."
),
},
},
}
def _predictive_model_available(_profile: dict[str, Any], _ctx: dict[str, Any]) -> tuple[bool, str]:
# Reserved contract slot: Layla's trained model is not registered in this
# runtime yet. Flip this to check for the model artifact / service once it
# is integrated, and it will supersede the empirical base rate.
return False, "Layla's validated predictive model is not yet registered in this runtime."
def _run_predictive_model(_profile: dict[str, Any], _ctx: dict[str, Any]) -> dict[str, Any]: # pragma: no cover
raise NotImplementedError(
"Publication-likelihood model not integrated. Register the trained model "
"and implement per-trial probability here."
)
def _llm_configured(_profile: dict[str, Any], ctx: dict[str, Any]) -> tuple[bool, str]:
from llm import build_client
if build_client(ctx["project_root"] / ".env") is not None:
return True, "eligible"
return False, "OpenAI API key not configured; using deterministic summary."
def _run_llm_summary(profile: dict[str, Any], ctx: dict[str, Any]) -> dict[str, Any]:
return {"status": "ok", "result": summarize_with_llm(profile, ctx["capabilities"], ctx["project_root"])}
def _run_template_summary(profile: dict[str, Any], ctx: dict[str, Any]) -> dict[str, Any]:
return {"status": "ok", "result": template_summary(profile, ctx["capabilities"])}
def _run_r_module_adapter(_profile: dict[str, Any], _ctx: dict[str, Any]) -> dict[str, Any]:
rscript = shutil.which("Rscript")
return {
"status": "not_configured",
"result": {
"rscript_available": bool(rscript),
"contract": "Imported projects under modules/ are read-only references, not runtime module folders.",
},
}
# --------------------------------------------------------------------------- #
# The registry
# --------------------------------------------------------------------------- #
REGISTRY: tuple[ModuleSpec, ...] = (
ModuleSpec(
name="protocol_completeness",
capability="protocol_completeness",
runtime="python",
precedence=10,
description="Checks whether major ClinicalTrials.gov-style protocol sections are filled.",
provenance="TIDE built-in",
applies=_always,
run=_run_protocol_completeness,
),
ModuleSpec(
name="historical_comparator",
capability="historical_comparator",
runtime="python",
precedence=10,
description="Reads archived domain CSVs from the imported publication-likelihood/timeliness study.",
provenance="PubTime (R-parity verified)",
applies=_domain_gate(("cancer", "covid", "cvd")),
run=_run_historical_comparator,
supported_domains=("cancer", "covid", "cvd"),
),
# ---- publication_outlook: two providers, selected by precedence ---- #
ModuleSpec(
name="publication_model",
capability="publication_outlook",
runtime="python",
precedence=100,
description="Validated per-trial publication-likelihood model (Layla's project).",
provenance="Predictive model (reserved)",
applies=_predictive_model_available,
run=_run_predictive_model,
),
ModuleSpec(
name="comparator_base_rate",
capability="publication_outlook",
runtime="python",
precedence=10,
description="Empirical publication/results-reporting rate from the matched historical cohort.",
provenance="Historical comparator",
applies=_always,
run=_run_comparator_base_rate,
),
# ---- narrative_summary: LLM interpretation, template fallback ---- #
ModuleSpec(
name="llm_summary",
capability="narrative_summary",
runtime="python",
precedence=100,
description="LLM (OpenAI Responses API) interpretation of the raw module outputs into plain language.",
provenance="OpenAI Responses API",
applies=_llm_configured,
run=_run_llm_summary,
),
ModuleSpec(
name="template_summary",
capability="narrative_summary",
runtime="python",
precedence=10,
description="Deterministic plain-language summary when no LLM is configured.",
provenance="TIDE built-in",
applies=_always,
run=_run_template_summary,
),
ModuleSpec(
name="r_module_adapter",
capability="r_runtime_adapter",
runtime="r",
precedence=10,
description="No R runtime modules are registered in this MVP.",
provenance="TIDE built-in",
applies=_always,
run=_run_r_module_adapter,
),
)
# --------------------------------------------------------------------------- #
# Selection + execution
# --------------------------------------------------------------------------- #
def run_registry(profile: dict[str, Any], project_root: Path) -> dict[str, Any]:
"""Select and run modules. Returns modules (by name), a capability index,
and a human-readable selection trace."""
ctx: dict[str, Any] = {"project_root": project_root, "capabilities": {}}
by_capability: "OrderedDict[str, list[ModuleSpec]]" = OrderedDict()
for spec in REGISTRY:
by_capability.setdefault(spec.capability, []).append(spec)
modules: dict[str, Any] = {}
selection: list[dict[str, Any]] = []
for capability, specs in by_capability.items():
evaluated = [(spec, *spec.applies(profile, ctx)) for spec in specs]
eligible = sorted(
(item for item in evaluated if item[1]),
key=lambda item: item[0].precedence,
reverse=True,
)
primary_spec = eligible[0][0] if eligible else None
candidates: list[dict[str, Any]] = []
for spec, ok, reason in evaluated:
role = "skipped"
status = "skipped"
result: Any = None
if spec is primary_spec:
role = "primary"
payload = spec.run(profile, ctx)
status = payload.get("status", "ok")
result = payload.get("result")
ctx["capabilities"][capability] = result
elif ok:
role = "superseded"
reason = f"eligible but superseded by '{primary_spec.name}' (higher precedence)."
modules[spec.name] = {
"status": status,
"language": spec.runtime,
"capability": capability,
"precedence": spec.precedence,
"selection": role,
"description": spec.description,
"provenance": spec.provenance,
"reason": reason,
"result": result,
}
candidates.append({"module": spec.name, "selection": role, "reason": reason})
selection.append(
{
"capability": capability,
"primary": primary_spec.name if primary_spec else None,
"candidates": candidates,
}
)
return {
"modules": modules,
"capabilities": ctx["capabilities"],
"pipeline": {"selection": selection},
}
def run_modules(profile: dict[str, Any], project_root: Path) -> dict[str, Any]:
"""Backward-compatible entry point: the module envelopes keyed by name."""
return run_registry(profile, project_root)["modules"]
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