Spaces:
Running on Zero
Running on Zero
File size: 12,879 Bytes
654bfe6 | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 | import React, { useState } from 'react';
import { EpiADRHyperparameters, EpochTrainingMetric, ModelTrainingSummary } from '../types';
import { globalEpiADREngine } from '../utils/epiAdrEngine';
import { SIDER_BENCHMARK_DRUGS } from '../utils/siderDataset';
import { ResponsiveContainer, LineChart, Line, XAxis, YAxis, Tooltip, CartesianGrid, Legend } from 'recharts';
import { Cpu, Play, Square, RotateCcw, Activity, Layers, CheckCircle, BarChart2, ShieldAlert } from 'lucide-react';
interface TrainingPanelProps {
useTissueConditioning: boolean;
setUseTissueConditioning: (val: boolean) => void;
}
export const TrainingPanel: React.FC<TrainingPanelProps> = ({
useTissueConditioning,
setUseTissueConditioning
}) => {
const [hyperparams, setHyperparams] = useState<EpiADRHyperparameters>({
useTissueConditioning,
crossAttentionHeads: 16,
learningRate: 0.001,
epochs: 40,
batchSize: 16,
optimizer: 'adam',
posWeight: 2.5,
regularizationL2: 0.001,
dropoutRate: 0.2,
mcDropoutPasses: 30
});
const [isTraining, setIsTraining] = useState<boolean>(false);
const [epochHistory, setEpochHistory] = useState<EpochTrainingMetric[]>([]);
const [trainingSummary, setTrainingSummary] = useState<ModelTrainingSummary | null>(null);
const handleStartTraining = async () => {
setIsTraining(true);
setEpochHistory([]);
setTrainingSummary(null);
try {
const summary = await globalEpiADREngine.trainEpiADRModel(
SIDER_BENCHMARK_DRUGS,
{ ...hyperparams, useTissueConditioning },
(metric) => {
setEpochHistory(prev => [...prev, metric]);
}
);
setTrainingSummary(summary);
} catch (err: any) {
console.error("Training error:", err);
} finally {
setIsTraining(false);
}
};
const handleStopTraining = () => {
globalEpiADREngine.cancelTraining();
setIsTraining(false);
};
return (
<div className="space-y-6">
{/* Training Configuration Grid */}
<div className="grid grid-cols-1 lg:grid-cols-12 gap-6">
{/* Left Column: Hyperparameter Controls */}
<div className="lg:col-span-4 bg-slate-900 border border-slate-800 rounded-2xl p-5 shadow-lg space-y-4">
<div className="flex items-center space-x-2 border-b border-slate-800 pb-3">
<Cpu className="w-5 h-5 text-indigo-400" />
<h2 className="text-base font-bold text-white">EpiADR-Net Model Architecture</h2>
</div>
{/* Mode Switcher */}
<div className="bg-slate-950 p-3 rounded-xl border border-slate-800 space-y-2">
<span className="text-xs font-semibold text-slate-300 block">Scientific Controlled Baseline</span>
<div className="flex space-x-2">
<button
onClick={() => {
setUseTissueConditioning(true);
setHyperparams({ ...hyperparams, useTissueConditioning: true });
}}
className={`flex-1 py-1.5 px-2 rounded-lg text-xs font-bold transition-all border ${
useTissueConditioning
? 'bg-indigo-600 text-white border-indigo-400 shadow-md'
: 'bg-slate-900 text-slate-400 border-slate-800'
}`}
>
Tissue-Conditioned
</button>
<button
onClick={() => {
setUseTissueConditioning(false);
setHyperparams({ ...hyperparams, useTissueConditioning: false });
}}
className={`flex-1 py-1.5 px-2 rounded-lg text-xs font-bold transition-all border ${
!useTissueConditioning
? 'bg-amber-600 text-white border-amber-400 shadow-md'
: 'bg-slate-900 text-slate-400 border-slate-800'
}`}
>
Molecule-Only
</button>
</div>
<p className="text-[11px] text-slate-400">
{useTissueConditioning
? 'Fuses SMILES 256-bit fingerprint with GTEx V8 128-dim organ transcriptomic vectors via 16-Head Cross-Attention.'
: 'Disables transcriptomic profiles to measure scientific accuracy uplift of human gene expression data.'}
</p>
</div>
{/* Hyperparameters */}
<div className="space-y-3 pt-1 text-xs">
<div className="space-y-1">
<div className="flex justify-between text-slate-300 font-semibold">
<span>Epochs</span>
<span className="font-mono text-indigo-300">{hyperparams.epochs}</span>
</div>
<input
type="range"
min="10"
max="100"
step="5"
disabled={isTraining}
value={hyperparams.epochs}
onChange={(e) => setHyperparams({ ...hyperparams, epochs: parseInt(e.target.value) })}
className="w-full accent-indigo-500 cursor-pointer h-1.5 bg-slate-800 rounded-lg"
/>
</div>
<div className="space-y-1">
<div className="flex justify-between text-slate-300 font-semibold">
<span>Learning Rate (η)</span>
<span className="font-mono text-indigo-300">{hyperparams.learningRate}</span>
</div>
<select
value={hyperparams.learningRate}
disabled={isTraining}
onChange={(e) => setHyperparams({ ...hyperparams, learningRate: parseFloat(e.target.value) })}
className="w-full bg-slate-950 border border-slate-800 rounded-xl px-3 py-1.5 text-xs text-slate-200"
>
<option value="0.005">0.005 (Fast)</option>
<option value="0.001">0.001 (Recommended)</option>
<option value="0.0003">0.0003 (Fine)</option>
</select>
</div>
<div className="space-y-1">
<div className="flex justify-between text-slate-300 font-semibold">
<span>Class Imbalance Weight (pos_weight)</span>
<span className="font-mono text-indigo-300">{hyperparams.posWeight}x</span>
</div>
<input
type="range"
min="1.0"
max="5.0"
step="0.5"
disabled={isTraining}
value={hyperparams.posWeight}
onChange={(e) => setHyperparams({ ...hyperparams, posWeight: parseFloat(e.target.value) })}
className="w-full accent-indigo-500 cursor-pointer h-1.5 bg-slate-800 rounded-lg"
/>
</div>
<div className="space-y-1">
<div className="flex justify-between text-slate-300 font-semibold">
<span>L2 Weight Regularization</span>
<span className="font-mono text-indigo-300">{hyperparams.regularizationL2}</span>
</div>
<input
type="range"
min="0"
max="0.01"
step="0.001"
disabled={isTraining}
value={hyperparams.regularizationL2}
onChange={(e) => setHyperparams({ ...hyperparams, regularizationL2: parseFloat(e.target.value) })}
className="w-full accent-indigo-500 cursor-pointer h-1.5 bg-slate-800 rounded-lg"
/>
</div>
</div>
{/* Controls */}
<div className="pt-3 border-t border-slate-800 flex space-x-2">
{!isTraining ? (
<button
onClick={handleStartTraining}
className="flex-1 py-3 bg-indigo-600 hover:bg-indigo-500 text-white rounded-xl font-bold text-xs shadow-lg flex items-center justify-center space-x-2 transition-all active:scale-95"
>
<Play className="w-4 h-4 fill-white" />
<span>Train EpiADR-Net</span>
</button>
) : (
<button
onClick={handleStopTraining}
className="flex-1 py-3 bg-rose-600 hover:bg-rose-500 text-white rounded-xl font-bold text-xs shadow-lg flex items-center justify-center space-x-2 transition-all"
>
<Square className="w-4 h-4 fill-white" />
<span>Halt Training</span>
</button>
)}
</div>
</div>
{/* Right Column: Live Epoch Loss & AUROC Charts */}
<div className="lg:col-span-8 bg-slate-900 border border-slate-800 rounded-2xl p-5 shadow-lg space-y-4">
<div className="flex items-center justify-between border-b border-slate-800 pb-3">
<div className="flex items-center space-x-2">
<Activity className="w-5 h-5 text-indigo-400" />
<h3 className="text-base font-bold text-white">Live Training & Validation Dynamics</h3>
</div>
{isTraining && (
<span className="flex items-center space-x-1 text-xs text-indigo-400 font-mono animate-pulse">
<span className="w-2 h-2 rounded-full bg-indigo-400"></span>
<span>Optimizing Epoch {epochHistory.length}/{hyperparams.epochs}...</span>
</span>
)}
</div>
{/* Loss Curve */}
<div className="h-52 bg-slate-950 p-2 rounded-xl border border-slate-800">
<span className="text-[11px] text-slate-400 font-mono font-semibold px-2 block">Binary Crossentropy Loss</span>
<ResponsiveContainer width="100%" height="85%">
<LineChart data={epochHistory}>
<CartesianGrid strokeDasharray="3 3" stroke="#1e293b" />
<XAxis dataKey="epoch" stroke="#64748b" fontSize={10} />
<YAxis stroke="#64748b" fontSize={10} domain={[0, 1]} />
<Tooltip contentStyle={{ backgroundColor: '#0f172a', borderColor: '#334155', borderRadius: '8px', fontSize: '11px' }} />
<Legend wrapperStyle={{ fontSize: '11px', paddingTop: '4px' }} />
<Line type="monotone" dataKey="trainLoss" stroke="#6366f1" strokeWidth={2} dot={false} name="Train Loss" />
<Line type="monotone" dataKey="valLoss" stroke="#f43f5e" strokeWidth={2} dot={false} name="Val Loss" />
</LineChart>
</ResponsiveContainer>
</div>
{/* AUROC Curve */}
<div className="h-52 bg-slate-950 p-2 rounded-xl border border-slate-800">
<span className="text-[11px] text-slate-400 font-mono font-semibold px-2 block">Validation AUROC Trajectory</span>
<ResponsiveContainer width="100%" height="85%">
<LineChart data={epochHistory}>
<CartesianGrid strokeDasharray="3 3" stroke="#1e293b" />
<XAxis dataKey="epoch" stroke="#64748b" fontSize={10} />
<YAxis stroke="#64748b" fontSize={10} domain={[0.5, 1.0]} />
<Tooltip contentStyle={{ backgroundColor: '#0f172a', borderColor: '#334155', borderRadius: '8px', fontSize: '11px' }} />
<Legend wrapperStyle={{ fontSize: '11px', paddingTop: '4px' }} />
<Line type="monotone" dataKey="valAUROC" stroke="#10b981" strokeWidth={2.5} dot={false} name="Validation AUROC" />
</LineChart>
</ResponsiveContainer>
</div>
{/* Model Training Summary Metrics */}
{trainingSummary && (
<div className="bg-slate-950 p-4 rounded-xl border border-indigo-500/30 grid grid-cols-2 sm:grid-cols-4 gap-3 text-center text-xs font-mono animate-fade-in">
<div>
<span className="text-slate-400 block text-[10px]">Validation AUROC</span>
<span className="text-emerald-400 font-bold text-base">{trainingSummary.finalValAUROC.toFixed(3)}</span>
</div>
<div>
<span className="text-slate-400 block text-[10px]">Macro F1 Score</span>
<span className="text-indigo-400 font-bold text-base">{trainingSummary.finalF1Score.toFixed(3)}</span>
</div>
<div>
<span className="text-slate-400 block text-[10px]">Final Loss</span>
<span className="text-rose-400 font-bold text-base">{trainingSummary.finalValLoss.toFixed(4)}</span>
</div>
<div>
<span className="text-slate-400 block text-[10px]">Training Duration</span>
<span className="text-slate-200 font-bold text-base">{trainingSummary.trainingTimeMs} ms</span>
</div>
</div>
)}
</div>
</div>
</div>
);
};
|