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
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ (
2
+ ()
3
+ -ii deficiency
4
+ /
5
+ //
6
+ 1d
7
+ 2c
8
+ 3-M
9
+ 3-methylcrotonyl-coa
10
+ 3-methylglutaconic
11
+ 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like
12
+ 3MC
13
+ 3c
14
+ 3p-
15
+ A
16
+ ABCD
17
+ ACCES
18
+ ADN
19
+ ADOCBL
20
+ ADULT
21
+ AIT
22
+ AMED
23
+ Aarskog-Scott
24
+ Abdominal
25
+ Abdominal obesity-metabolic
26
+ Ablepharon-macrostomia
27
+ Abruzzo-Erickson
28
+ Achalasia-addisonianism-alacrimia
29
+ Achille
30
+ Acrocallosal
31
+ Acropectoral
32
+ Adams-Oliver
33
+ Addison
34
+ Advance
35
+ Advance sleep phase
36
+ Advanced
37
+ Advanced sleep phase
38
+ Advanced sleep-phase
39
+ Agenesis
40
+ Agenesis of corpus callosum, cardiac, ocular, and genital
41
+ Aicardi
42
+ Aicardi-Goutieres
43
+ Al
44
+ Al Kaissi
45
+ Al-Gazali
46
+ Al-Gazali-Bakalinova
47
+ Al-Raqad
48
+ Alacrima
49
+ Alacrima, achalasia, and impaired intellectual development
50
+ Alagille
51
+ Alazami
52
+ Alazami-Yuan
53
+ Albinism-deafness
54
+ Alkuraya-Kucinskas
55
+ Allan-Herndon-Dudley
56
+ Alopecia
57
+ Alopecia, neurologic defects, and endocrinopathy
58
+ Alopecia-intellectual
59
+ Alopecia-intellectual disability
60
+ Alpha-thalassemia
61
+ Alpha-thalassemia myelodysplasia
62
+ Alpha-thalassemia/impaired
63
+ Alpha-thalassemia/impaired intellectual development
64
+ Alpha-thalassemia/mental
65
+ Alpha-thalassemia/mental retardation
66
+ Alport
67
+ Alstrom
68
+ Alzahrani-Kuwahara
69
+ Alzheimer
70
+ Amelia
71
+ Amelia, posterior, with pelvic and pulmonary hypoplasia
72
+ Amelogenesis
73
+ Amelogenesis imperfecta, type IG (enamel-renal
74
+ Andersen
75
+ Angelman
76
+ Antiphospholipid
77
+ Antley-Bixler
78
+ Apert
79
+ Arboleda-Tham
80
+ Arnold-Chiari
81
+ Aromatase
82
+ Aromatase excess
83
+ Arterial
84
+ Arterial tortuosity
85
+ Arts
86
+ Asperger
87
+ Ataxia
88
+ Ataxia, intention tremor, and hypotonia
89
+ Ataxia-pancytopenia
90
+ Atelis
91
+ Athabaskan
92
+ Athabaskan brainstem dysgenesis
93
+ Atrioventricular
94
+ Atrioventricular septal defect, partial, with heterotaxy
95
+ Au-Kline
96
+ Auriculocondylar
97
+ Autoimmune
98
+ Autoimmune lymphoproliferative
99
+ Autoimmune polyendocrinopathy
100
+ Autoinflammation
101
+ Autoinflammation, antibody deficiency, and immune dysregulation
102
+ Autoinflammation, panniculitis, and dermatosis
103
+ Autoinflammatory
104
+ Autoinflammatory-pancytopenia
105
+ Axenfeld-Rieger
106
+ Ayme-Gripp
107
+ B1
108
+ B2
109
+ B6
110
+ B9
111
+ BDV
112
+ Bachmann-Bupp
113
+ Bainbridge-Ropers
114
+ Baker-Gordon
115
+ Baller-Gerold
116
+ Bamforth-Lazarus
117
+ Baraitser-Winter
118
+ Baralle-Macken
119
+ Barber-Say
120
+ Bardet-Biedl
121
+ Bare
122
+ Bare lymphocyte
123
+ Bart-Pumphrey
124
+ Barth
125
+ Bartter
126
+ Basal
127
+ Basal cell nevus
128
+ Basan
129
+ Basel-Vanagait-Smirin-Yosef
130
+ Basilicata-Akhtar
131
+ Bazex
132
+ Beare-Stevenson
133
+ Beare-Stevenson cutis gyrata
134
+ Beaulieu-Boycott-Innes
135
+ Beck-Fahrner
136
+ Beckwith-Wiedemann
137
+ Behr
138
+ Bell
139
+ Bent
140
+ Bent bone dysplasia
141
+ Berger
142
+ Bernard-Soulier
143
+ Best
144
+ Biliary
145
+ Biliary, renal, neurologic, and skeletal
146
+ Birk-Barel
147
+ Birk-Landau-Perez
148
+ Birt-Hogg-Dube
149
+ Bjornstad
150
+ Blau
151
+ Blepharocheilodontic
152
+ Blepharophimosis-impaired
153
+ Blepharophimosis-impaired intellectual development
154
+ Bloom
155
+ Bohring-Opitz
156
+ Bone
157
+ Bone marrow failure
158
+ Bone marrow failure and diabetes mellitus
159
+ Bor-Duane
160
+ Bor-Duane hydrocephalus contiguous gene
161
+ Borjeson-Forssman-Lehmann
162
+ Bosch-Boonstra-Schaaf
163
+ Bosch-Boonstra-Schaaf optic atrophy
164
+ Bosley-Salih-Alorainy
165
+ Bosma
166
+ Bosma arhinia microphthalmia
167
+ Boucher-Neuhauser
168
+ Boudin-Mortier
169
+ Bowen-Conradi
170
+ Brachydactyly-syndactyly
171
+ Braddock-Carey
172
+ Brain
173
+ Brain tumor-polyposis
174
+ Branchial
175
+ Branchial arch abnormalities, choanal atresia, athelia, hearing loss, and hypothyroidism
176
+ Branchiooculofacial
177
+ Branchiootic
178
+ Branchiootorenal
179
+ Brittle
180
+ Brittle cornea
181
+ Brooke-Spiegler
182
+ Brown-Vialetto-Van
183
+ Brown-Vialetto-Van Laere
184
+ Bruck
185
+ Brugada
186
+ Brunet-Wagner
187
+ Brunet-Wagner neurodevelopmental
188
+ Brunner
189
+ Bryant-Li-Bhoj
190
+ Bryant-Li-Bhoj neurodevelopmental
191
+ Budd-Chiari
192
+ Buratti-Harel
193
+ Burn-McKeown
194
+ Buschke-Ollendorff
195
+ C
196
+ C2-C3
197
+ CAE
198
+ CAPOS
199
+ CARASIL
200
+ CATIFA
201
+ CATSHL
202
+ CBH
203
+ CD4+
204
+ CD8+
205
+ CDAGS
206
+ CEBALID
207
+ CHAND
208
+ CHARGE
209
+ CHILD
210
+ CHIME
211
+ CHOPS
212
+ CIMDAG
213
+ CINCA
214
+ CK
215
+ CLAPO
216
+ CLOVE
217
+ COACH
218
+ CODAS
219
+ COMMAD
220
+ CPK
221
+ CRASH
222
+ Camptodactyly-arthropathy-coxa
223
+ Camptodactyly-arthropathy-coxa vara-pericarditis
224
+ Cardiac
225
+ Cardiac arrhythmia
226
+ Cardiac-urogenital
227
+ Cardiofaciocutaneous
228
+ Cardiofacioneurodevelopmental
229
+ Cardiospondylocarpofacial
230
+ Carey-Fineman-Ziter
231
+ Carpal
232
+ Carpal tunnel
233
+ Carpenter
234
+ Caspase
235
+ Caspase 8 lymphadenopathy
236
+ Cat
237
+ Cat eye
238
+ Catel-Manzke
239
+ Caudal
240
+ Caudal regression
241
+ Cayler
242
+ Cayler cardiofacial
243
+ Cenani-Lenz
244
+ Cenani-Lenz syndactyly
245
+ Central
246
+ Central hypoventilation
247
+ Cerebellar
248
+ Cerebellar ataxia, impaired intellectual development and dysequilibrium
249
+ Cerebellar ataxia, impaired intellectual development, and dysequilibrium
250
+ Cerebellar ataxia, impaired intellectual development, and dysquilibrium
251
+ Cerebellar ataxia, neuropathy, and vestibular areflexia
252
+ Cerebellar hypoplasia, impaired intellectual development, and dysequilibrium
253
+ Cerebellar, ocular, craniofacial, and genital
254
+ Cerebellofaciodental
255
+ Cerebral
256
+ Cerebral creatine deficiency
257
+ Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma
258
+ Cerebral-cerebellar-coloboma
259
+ Cerebrocostomandibular
260
+ Cerebrooculofacioskeletal
261
+ Chanarin-Dorfman
262
+ Char
263
+ Chediak-Higashi
264
+ Chilton-Okur-Chung
265
+ Chilton-Okur-Chung neurodevelopmental
266
+ Chitayat
267
+ Cholestasis-lymphedema
268
+ Chopra-Amiel-Gordon
269
+ Chromosome
270
+ Chromosome 10q22.3-q23.2 deletion
271
+ Chromosome 10q26 deletion
272
+ Chromosome 11p13 deletion
273
+ Chromosome 11p15-p14 deletion
274
+ Chromosome 13q14 deletion
275
+ Chromosome 13q33-q34 deletion
276
+ Chromosome 14q11-q22 deletion
277
+ Chromosome 15q11.2 deletion
278
+ Chromosome 15q13.3 microdeletion
279
+ Chromosome 15q14 deletion
280
+ Chromosome 15q25 deletion
281
+ Chromosome 15q26-qter deletion
282
+ Chromosome 16p11.2 deletion
283
+ Chromosome 16p11.2 duplication
284
+ Chromosome 16p12.1 deletion
285
+ Chromosome 16p12.2-p11.2 deletion
286
+ Chromosome 16p13.3 deletion
287
+ Chromosome 16p13.3 duplication
288
+ Chromosome 16q12 duplication
289
+ Chromosome 16q22 deletion
290
+ Chromosome 17p13.1 deletion
291
+ Chromosome 17p13.3 duplication
292
+ Chromosome 17q11.2 deletion
293
+ Chromosome 17q11.2 duplication
294
+ Chromosome 17q12 deletion
295
+ Chromosome 17q12 duplication
296
+ Chromosome 17q21.31 duplication
297
+ Chromosome 17q23.1-q23.2 deletion
298
+ Chromosome 17q23.1-q23.2 duplication
299
+ Chromosome 18p deletion
300
+ Chromosome 18q deletion
301
+ Chromosome 19p13.13 deletion
302
+ Chromosome 19p13.13 duplication
303
+ Chromosome 19q13.11 deletion
304
+ Chromosome 1p35 deletion
305
+ Chromosome 1p36 deletion
306
+ Chromosome 1p36.33 duplication
307
+ Chromosome 1q21.1 deletion
308
+ Chromosome 1q21.1 duplication
309
+ Chromosome 1q41-q42 deletion
310
+ Chromosome 22q11.2 deletion
311
+ Chromosome 22q11.2 microduplication
312
+ Chromosome 22q13 duplication
313
+ Chromosome 2p12-p11.2 deletion
314
+ Chromosome 2p16.1-p15 deletion
315
+ Chromosome 2q31.1 duplication
316
+ Chromosome 2q31.2 deletion
317
+ Chromosome 2q37 deletion
318
+ Chromosome 3q13.31 deletion
319
+ Chromosome 3q29 microdeletion
320
+ Chromosome 3q29 microduplication
321
+ Chromosome 4q21 deletion
322
+ Chromosome 4q32.1-q32.2 triplication
323
+ Chromosome 5p13 duplication
324
+ Chromosome 5q12 deletion
325
+ Chromosome 5q14.3 deletion
326
+ Chromosome 6pter-p24 deletion
327
+ Chromosome 6q11-q14 deletion
328
+ Chromosome 6q25-q25 deletion
329
+ Chromosome 7q11.23 deletion
330
+ Chromosome 7q11.23 duplication
331
+ Chromosome 8p11 myeloproliferative
332
+ Chromosome 8q21.11 deletion
333
+ Chromosome 9p deletion
334
+ Chromosome Xp11.23-p11.22 duplication
335
+ Chromosome Xp11.3 deletion
336
+ Chromosome Xp21 deletion
337
+ Chromosome Xq13 duplication
338
+ Chromosome Xq26.3 duplication
339
+ Chromosome Xq27.3-q28 duplication
340
+ Chromosome Xq28 duplication
341
+ Chudley-McCullough
342
+ Chung-Jansen
343
+ Cleft
344
+ Cleft lip/palate-ectodermal dysplasia
345
+ Cockayne
346
+ Cocoon
347
+ Coffin-Lowry
348
+ Coffin-Siris
349
+ Cohen
350
+ Cohen-Gibson
351
+ Cold-induced
352
+ Cold-induced sweating
353
+ Cole-Carpenter
354
+ Combined
355
+ Combined osteogenesis imperfecta and Ehlers-Danlos
356
+ Cone-rod
357
+ Cone-rod synaptic disorder
358
+ Congenital
359
+ Congenital anomalies of kidney and urinary tract
360
+ Congenital heart defects and skeletal malformations
361
+ Congenital short bowel
362
+ Conotruncal
363
+ Conotruncal anomaly face
364
+ Contractures
365
+ Contractures, pterygia, and spondylocarpostarsal fusion
366
+ Contractures, pterygia, and spondylocarpotarsal fusion
367
+ Cornelia
368
+ Cornelia de Lange
369
+ Costello
370
+ Cousin
371
+ Cowchock
372
+ Cowden
373
+ Craniofacial
374
+ Craniofacial anomalies and anterior segment dysgenesis
375
+ Craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development
376
+ Craniofacial-deafness-hand
377
+ Craniofacioskeletal
378
+ Crigler-Najjar
379
+ Crohn
380
+ Crouzon
381
+ Culler-Jones
382
+ Currarino
383
+ Curry-Jones
384
+ Cushing
385
+ Cutaneous
386
+ Cutaneous telangiectasia and cancer
387
+ D3
388
+ DEEAH
389
+ DEGCAGS
390
+ DOORS
391
+ Dalton
392
+ Dandy-Walker
393
+ De
394
+ De Sanctis-Cacchione
395
+ Delayed
396
+ Delayed sleep phase
397
+ Delpire-McNeill
398
+ Dentici-Novelli
399
+ Dentici-Novelli neurodevelopmental
400
+ Denys-Drash
401
+ Desanto-Shinawi
402
+ DiGeorge
403
+ Dias-Logan
404
+ Diencephalic-mesencephalic
405
+ Diencephalic-mesencephalic junction dysplasia
406
+ Diets-Jongmans
407
+ Diffuse
408
+ Diffuse gastric and lobular breast cancer
409
+ Donnai-Barrow
410
+ Donohue
411
+ Down
412
+ Dravet
413
+ Duane
414
+ Duane retraction
415
+ Duane-radial
416
+ Duane-radial ray
417
+ Dubin-Johnson
418
+ Dursun
419
+ Dworschak-Punetha
420
+ Dworschak-Punetha neurodevelopmental
421
+ E
422
+ EDICT
423
+ EEC
424
+ EEG
425
+ EMG
426
+ ENDOVE
427
+ ERG
428
+ Ebstein
429
+ Ectodermal
430
+ Ectodermal dysplasia-syndactyly
431
+ Ectodermal dysplasia/short stature
432
+ Ectodermal dysplasia/skin fragility
433
+ Ectrodactyly
434
+ Ectrodactyly, ectodermal dysplasia, and cleft lip/palate
435
+ Ehlers-Danlos
436
+ Eiken
437
+ Ellis-van
438
+ Ellis-van Creveld
439
+ Elsahy-Waters
440
+ Emanuel
441
+ Emberger
442
+ Enhanced
443
+ Enhanced S-cone
444
+ Epidermolysis
445
+ Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic
446
+ Episodic
447
+ Episodic ataxia/myokymia
448
+ Episodic pain
449
+ Escobar
450
+ Even-plus
451
+ Exfoliation
452
+ FAV
453
+ FG
454
+ FILS
455
+ FINCA
456
+ Facial
457
+ Facial dysmorphism, hypertrichosis, epilepsy, intellectual/developmental delay, and gingival overgrowth
458
+ Fallot
459
+ Familial
460
+ Familial apolipoprotein gene cluster deletion
461
+ Familial cold autoinflammatory
462
+ Familial cold inflammatory
463
+ Fanconi
464
+ Fanconi renotubular
465
+ Fanconi-Bickel
466
+ Faundes-Banka
467
+ Feingold
468
+ Ferguson-Bonni
469
+ Ferguson-Bonni neurodevelopmental
470
+ Filippi
471
+ Floating-Harbor
472
+ Focal
473
+ Focal segmental glomerulosclerosis and neurodevelopmental
474
+ Fontaine
475
+ Fontaine progeroid
476
+ Forsythe-Wakeling
477
+ Fragile
478
+ Fragile X
479
+ Fragile X tremor/ataxia
480
+ Frank-ter
481
+ Frank-ter Haar
482
+ Fraser
483
+ Frasier
484
+ Frias
485
+ Fuhrmann
486
+ G
487
+ GAND
488
+ GAPO
489
+ GH
490
+ GLOW
491
+ GLUT1
492
+ GLUT1 deficiency
493
+ GRACILE
494
+ Gabriele-de
495
+ Gabriele-de Vries
496
+ Galloway-Mowat
497
+ Gardner
498
+ Gastrointestinal
499
+ Gastrointestinal defects and immunodeficiency
500
+ Gastrointestinal stromal tumor/GIST-plus
501
+ Genitopatellar
502
+ Genitourinary
503
+ Genitourinary and/or/brain malformation
504
+ Ghosal
505
+ Ghosal hematodiaphyseal
506
+ Gilbert
507
+ Gilles
508
+ Gilles de la Tourette
509
+ Gillespie
510
+ Gillessen-Kaesbach-Nishimura
511
+ Gitelman
512
+ Glass
513
+ Goeminne
514
+ Goeminne TKCR
515
+ Goldberg-Shprintzen
516
+ Goldberg-Shprintzen megacolon
517
+ Grange
518
+ Gray
519
+ Gray platelet
520
+ Greig
521
+ Greig cephalopolysyndactyly
522
+ Griscelli
523
+ Groupe
524
+ Gustavson
525
+ Guttmacher
526
+ HARP
527
+ HELIX
528
+ HELLP
529
+ Haim-Munk
530
+ Hajdu-Cheney
531
+ Halperin-Birk
532
+ Hamamy
533
+ Hand-foot-uterus
534
+ Hao-Fountain
535
+ Hardikar
536
+ Harel-Yoon
537
+ Hartsfield
538
+ Hay-Wells
539
+ Heart
540
+ Heart and brain malformation
541
+ Heart-hand
542
+ Heimler
543
+ Helsmoortel-van
544
+ Helsmoortel-van der Aa
545
+ Hemolytic
546
+ Hemolytic uremic
547
+ Hengel-Maroofian-Schols
548
+ Hennekam
549
+ Hennekam lymphangiectasia-lymphedema
550
+ Hermansky-Pudlak
551
+ Heyn-Sproul-Jackson
552
+ Hiatt-Neu-Cooper
553
+ Hiatt-Neu-Cooper neurodevelopmental
554
+ Hirschsprung
555
+ Histiocytosis-lymphadenopathy
556
+ Histiocytosis-lymphadenopathy plus
557
+ Hodgkin
558
+ Holt-Oram
559
+ Huriez
560
+ Hyaline
561
+ Hyaline fibromatosis
562
+ Hydrolethalus
563
+ Hyper-IgD
564
+ Hyper-IgE
565
+ Hyper-IgE recurrent infection
566
+ Hypereosinophilic
567
+ Hyperferritinemia-cataract
568
+ Hyperimmunoglobulin
569
+ Hyperimmunoglobulin G1
570
+ Hyperinsulinism-hyperammonemia
571
+ Hyperornithinemia-hyperammonemia-homocitrullinemia
572
+ Hyperparathyroidism-jaw
573
+ Hyperparathyroidism-jaw tumor
574
+ Hyperphosphatasia
575
+ Hyperphosphatasia with impaired intellectual development
576
+ Hypersensitivity
577
+ Hypertension
578
+ Hypertension and brachydactyly
579
+ Hypertrichotic
580
+ Hypertrichotic osteochondrodysplasia (Cantu
581
+ Hypocalcemia
582
+ Hypocalcemia, autosomal dominant, with Bartter
583
+ Hypogonadotropic
584
+ Hypogonadotropic hypogonadism 1 with or without anosmia (Kallmann
585
+ Hypoparathyroidism-retardation-dysmorphism
586
+ Hypoplastic
587
+ Hypoplastic left heart
588
+ Hypotonia
589
+ Hypotonia, ataxia, and delayed development
590
+ Hypotonia, ataxia, developmental delay, and tooth enamel defect
591
+ Hypotonia-cystinuria
592
+ Hypotrichosis-lymphedema-telangiectasia
593
+ Hypotrichosis-lymphedema-telangiectasia-renal
594
+ Hypotrichosis-lymphedema-telangiectasia-renal defect
595
+ Hz
596
+ I
597
+ IFAP
598
+ II
599
+ III
600
+ IMAGE
601
+ IMAGE-I
602
+ IRM
603
+ IV
604
+ IVIC
605
+ IX
606
+ Ichthyosis
607
+ Ichthyosis prematurity
608
+ Ichthyosis, follicular, with atrichia and photophobia
609
+ IgE
610
+ IgG
611
+ IgM
612
+ Imagawa-Matsumoto
613
+ Imerslund-Grasbeck
614
+ Immune
615
+ Immune dysregulation and systemic hyperinflammation
616
+ Immunodeficiency-centromeric
617
+ Immunodeficiency-centromeric instability-facial anomalies
618
+ Infantile
619
+ Infantile liver failure
620
+ Intellectual
621
+ Intellectual disability and myopathy
622
+ Intellectual disability-hypotonic facies
623
+ Intestinal
624
+ Intestinal dysmotility
625
+ Ischiocoxopodopatellar
626
+ Jaberi-Elahi
627
+ Jackson-Weiss
628
+ Jacobsen
629
+ Jalili
630
+ Jansen
631
+ Jansen de Vries
632
+ Jawad
633
+ Jervell
634
+ Jervell and Lange-Nielsen
635
+ Johanson-Blizzard
636
+ Joubert
637
+ Juberg-Hayward
638
+ Juvenile
639
+ Juvenile polyposis/hereditary hemorrhagic telangiectasia
640
+ KBG
641
+ KINSSHIP
642
+ Kabuki
643
+ Kagami-Ogata
644
+ Kahrizi
645
+ Kaufman
646
+ Kaufman oculocerebrofacial
647
+ Kaya-Barakat-Masson
648
+ Keipert
649
+ Kenny-Caffey
650
+ Keppen-Lubinsky
651
+ Keratitis-ichthyosis-deafness
652
+ Keratoderma-ichthyosis-deafness
653
+ Keutel
654
+ Khan-Khan-Katsanis
655
+ Kilquist
656
+ Kindler
657
+ King-Denborough
658
+ Kleefstra
659
+ Klippel-Feil
660
+ Klippel-Trenaunay-Weber
661
+ Knobloch
662
+ Kohlschutter-Tonz
663
+ Kondoh
664
+ Koolen-De
665
+ Koolen-De Vries
666
+ Kosaki
667
+ Kosaki overgrowth
668
+ Kowarski
669
+ Kufor-Rakeb
670
+ Kury-Isidor
671
+ LADD
672
+ LCR
673
+ LEOPARD
674
+ LIG4
675
+ Lamb-Shaffer
676
+ Langerhans
677
+ Larsen
678
+ Larsen-like
679
+ Lateral
680
+ Lateral meningocele
681
+ Laurence-Moon
682
+ Laurin-Sandrow
683
+ Leber
684
+ Legius
685
+ Leri
686
+ Leri pleonosteosis chromosome duplication
687
+ Lesch-Nyhan
688
+ Lessel-Kreienkamp
689
+ Lessel-Kubisch
690
+ Lethal
691
+ Lethal congenital contractural
692
+ Lethal congenital contracture
693
+ Leukemia
694
+ Leukemia, megakaryoblastic, with or without Down
695
+ Leukemia, transient, of Down
696
+ Leukoencephalopathy
697
+ Leukoencephalopathy, developmental delay, and episodic neurologic regression
698
+ Leukoencephalopathy, motor delay, spasticity, and dysarthria
699
+ Levy-Shanske
700
+ Li-Campeau
701
+ Li-Fraumeni
702
+ Li-Ghorgani-Weisz-Hubshman
703
+ Liang-Wang
704
+ Liberfarb
705
+ Lichtenstein-Knorr
706
+ Liddle
707
+ Liebenberg
708
+ Limb-mammary
709
+ Loeys-Dietz
710
+ Long
711
+ Long QT
712
+ Lopes-Maciel-Rodan
713
+ Lowe
714
+ Lowry-Wood
715
+ Lujan-Fryns
716
+ Lung
717
+ Lung disease, immunodeficiency, and chromosome breakage
718
+ Luo-Schoch-Yamamoto
719
+ Luscan-Lumish
720
+ Lymphedema-distichiasis
721
+ Lymphoproliferative
722
+ Lynch
723
+ MASA
724
+ MASS
725
+ MEDNIK
726
+ MEHMO
727
+ MEND
728
+ MIRAGE
729
+ Macrocephaly/autism
730
+ Macrocephaly/megalencephaly
731
+ Majeed
732
+ Malan
733
+ Malouf
734
+ Mammary-digital-nail
735
+ Mandibular
736
+ Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy
737
+ Mandibuloacral
738
+ Mandibuloacral dysplasia progeroid
739
+ Manitoba
740
+ Manitoba oculotrichoanal
741
+ Marbach-Rustad
742
+ Marbach-Rustad progeroid
743
+ Marbach-Schaaf
744
+ Marbach-Schaaf neurodevelopmental
745
+ Marden-Walker
746
+ Marfan
747
+ Marfan lipodystrophy
748
+ Marinesco-Sjogren
749
+ Marshall
750
+ Marshall-Smith
751
+ Marsili
752
+ Martin-Probst
753
+ Martsolf
754
+ Mast
755
+ McCune-Albright
756
+ McKusick-Kaufman
757
+ McLeod
758
+ Meacham
759
+ Meckel
760
+ Medulloblastoma
761
+ Medulloblastoma predisposition
762
+ Meester-Loeys
763
+ Mega-corpus-callosum
764
+ Megacystis-microcolon-intestinal
765
+ Megacystis-microcolon-intestinal hypoperistalsis
766
+ Megalencephaly-capillary
767
+ Megalencephaly-capillary malformation-polymicrogyria
768
+ Megalencephaly-polymicrogyria-polydactyly-hydrocephalus
769
+ Meier-Gorlin
770
+ Melanocytic
771
+ Melanocytic nevus
772
+ Melanoma
773
+ Melanoma and neural system tumor
774
+ Melanoma-pancreatic
775
+ Melanoma-pancreatic cancer
776
+ Melkersson-Rosenthal
777
+ Melnick-Needles
778
+ Menke-Hennekam
779
+ Mesomelia-synostoses
780
+ Metabolic
781
+ Microcephaly
782
+ Microcephaly, developmental delay, and brittle hair
783
+ Microcephaly, epilepsy, and diabetes
784
+ Microcephaly, facial dysmorphism, renal agenesis, and ambiguous genitalia
785
+ Microcephaly-capillary
786
+ Microcephaly-capillary malformation
787
+ Microcephaly-micromelia
788
+ Microphthalmia/coloboma
789
+ Microphthalmia/coloboma and skeletal dysplasia
790
+ Miller
791
+ Miller-Dieker
792
+ Miller-Dieker lissencephaly
793
+ Mismatch
794
+ Mismatch repair cancer
795
+ Mitchell
796
+ Mitchell-Riley
797
+ Mitochondrial
798
+ Mitochondrial DNA depletion
799
+ Mitochondrial recessive ataxia
800
+ Moebius
801
+ Mohr-Tranebjaerg
802
+ Monosomy
803
+ Monosomy 7 myelodysplasia and leukemia
804
+ Morgagni-Stewart-Morel
805
+ Mosaic
806
+ Mosaic variegated aneuploidy
807
+ Mowat-Wilson
808
+ Muckle-Wells
809
+ Mucopolysaccharidosis-plus
810
+ Muenke
811
+ Muir-Torre
812
+ Mulchandani-Bhoj-Conlin
813
+ Mullegama-Klein-Martinez
814
+ Multicentric
815
+ Multicentric carpotarsal osteolysis
816
+ Multiple
817
+ Multiple congenital anomalies-hypotonia-seizures
818
+ Multiple congenital anomalies-neurodevelopmental
819
+ Multiple mitochondrial dysfunctions
820
+ Multiple pterygium
821
+ Multiple synostoses
822
+ Multisystemic
823
+ Multisystemic smooth muscle dysfunction
824
+ Mungan
825
+ Muscular
826
+ Muscular dystrophy, congenital hearing loss, and ovarian insufficiency
827
+ Myasthenic
828
+ Myelodysplasia
829
+ Myelodysplastic
830
+ Myhre
831
+ Myoectodermal
832
+ Myoectodermal gonadal dysgenesis
833
+ Ménétrier
834
+ NESCAV
835
+ NOR
836
+ NOR polyagglutination
837
+ Nabais
838
+ Nabais Sa-de Vries
839
+ Nablus
840
+ Nablus mask-like facial
841
+ Naegeli-Franceschetti-Jadassohn
842
+ Nail-patella
843
+ Nance-Horan
844
+ Neisseria
845
+ Nephrogenic
846
+ Nephrotic
847
+ Nestor-Guillermo
848
+ Nestor-Guillermo progeria
849
+ Netherton
850
+ Neu-Laxova
851
+ Neurocardiofaciodigital
852
+ Neurodevelopmental
853
+ Neurodevelopmental, jaw, eye, and digital
854
+ Neurodevelopmental-craniofacial
855
+ Neurofacioskeletal
856
+ Neurofibromatosis-Noonan
857
+ Neuroocular
858
+ Neurooculocardiogenitourinary
859
+ Nicolaides-Baraitser
860
+ Nijmegen
861
+ Nijmegen breakage
862
+ Nikolsky
863
+ Nivelon-Nivelon-Mabille
864
+ Nizon-Isidor
865
+ Noonan
866
+ O'Donnell-Luria-Rodan
867
+ Occipital
868
+ Occipital horn
869
+ Oculoauricular
870
+ Oculoectodermal
871
+ Oculogastrointestinal
872
+ Oculogastrointestinal neurodevelopmental
873
+ Oculoskeletodental
874
+ Ogden
875
+ Ohdo
876
+ Okur-Chung
877
+ Okur-Chung neurodevelopmental
878
+ Oligodontia-colorectal
879
+ Oligodontia-colorectal cancer
880
+ Oliver-McFarlane
881
+ Olmsted
882
+ Omenn
883
+ Onychodystrophy
884
+ Onychodystrophy, osteodystrophy, impaired intellectual development, and seizures
885
+ Opitz
886
+ Opitz GBBB
887
+ Opitz-Kaveggia
888
+ Optic
889
+ Optic atrophy plus
890
+ Orofaciodigital
891
+ Osteootohepatoenteric
892
+ Osteoporosis-pseudoglioma
893
+ Ota
894
+ Otodental
895
+ Otodental dysplasia chromosome deletion
896
+ Otofaciocervical
897
+ Otopalatodigital
898
+ Ovarian
899
+ Ovarian hyperstimulation
900
+ PCWH
901
+ PEA
902
+ PEHO
903
+ PERCHING
904
+ PEV
905
+ Paganini-Miozzo
906
+ Pallister-Hall
907
+ Pallister-Hall-like
908
+ Pallister-Killian
909
+ Panic
910
+ Panic disorder
911
+ Papillon-Lefevre
912
+ Papillorenal
913
+ Parenti-Mignot
914
+ Parenti-Mignot neurodevelopmental
915
+ Partington
916
+ Pectus
917
+ Peeling
918
+ Peeling skin
919
+ Pelger-Huët
920
+ Pendred
921
+ Periodic
922
+ Periodic fever, immunodeficiency, and thrombocytopenia
923
+ Perlman
924
+ Perrault
925
+ Perry
926
+ Persistent
927
+ Persistent Mullerian duct
928
+ Peters-plus
929
+ Pettigrew
930
+ Peutz-Jeghers
931
+ Pfeiffer
932
+ Phelan-McDermid
933
+ Pick
934
+ Pierpont
935
+ Pierre
936
+ Pierre Robin
937
+ Pierson
938
+ Pigmentosum
939
+ Pilarowski-Bjornsson
940
+ Pitt-Hopkins
941
+ Pitt-Hopkins like
942
+ Pitt-Hopkins-like
943
+ Poirier-Bienvenu
944
+ Poirier-Bienvenu neurodevelopmental
945
+ Polycystic
946
+ Polycystic ovary
947
+ Polyendocrine-polyneuropathy
948
+ Polyposis
949
+ Pontocerebellar
950
+ Pontocerebellar hypoplasia, hypotonia, and respiratory insufficiency
951
+ Popliteal
952
+ Popliteal pterygium
953
+ Poretti-Boltshauser
954
+ Potocki-Lupski
955
+ Potocki-Shaffer
956
+ Prader-Willi
957
+ Premature
958
+ Premature aging
959
+ Prieto
960
+ Primordial
961
+ Primordial dwarfism-immunodeficiency-lipodystrophy
962
+ Primrose
963
+ Proliferative
964
+ Proliferative vasculopathy and hydranencephaly-hydrocephaly
965
+ Proteasome-associated
966
+ Proteasome-associated autoinflammatory
967
+ Proteus
968
+ Proud
969
+ Prune
970
+ Prune belly
971
+ Pseudo-TORCH
972
+ Quincke
973
+ RAPADILINO
974
+ RAS-associated
975
+ RAS-associated autoimmune lymphoproliferative
976
+ RHYNS
977
+ RIDDLE
978
+ ROSAH
979
+ Rabin-Pappas
980
+ Rabson-Mendenhall
981
+ Radiation
982
+ Radiation sensitivity/chromosome instability
983
+ Radio-Tartaglia
984
+ Rafiq
985
+ Rahman
986
+ Raine
987
+ Rapp-Hodgkin
988
+ Rauch-Steindl
989
+ Raynaud-Claes
990
+ Renal
991
+ Renal cysts and diabetes
992
+ Renpenning
993
+ Restless
994
+ Restless legs
995
+ Retinal
996
+ Retinal disease in Usher
997
+ Retinal dystrophy, iris coloboma, and comedogenic acne
998
+ Retinal dystrophy, juvenile cataracts, and short stature
999
+ Rett
1000
+ Revesz
1001
+ Reynolds
1002
+ Rhabdoid
1003
+ Rhabdoid tumor predisposition
1004
+ Rieger
1005
+ Rigidity
1006
+ Rigidity and multifocal seizure
1007
+ Ring
1008
+ Ring chromosome 14
1009
+ Ritscher-Schinzel
1010
+ Roberts-SC
1011
+ Roberts-SC phocomelia
1012
+ Robinow
1013
+ Robinow-Sorauf
1014
+ Roifman
1015
+ Roifman-Chitayat
1016
+ Rothmund-Thomson
1017
+ Roussy-Levy
1018
+ Rubinstein-Taybi
1019
+ Ruijs-Aalfs
1020
+ S-sulfocystéine
1021
+ SAOS
1022
+ SBBYSS
1023
+ SERKAL
1024
+ SESAME
1025
+ SHORT
1026
+ SIMHA
1027
+ SLA
1028
+ SNC
1029
+ SNP
1030
+ STAR
1031
+ Saethre-Chotzen
1032
+ Salt
1033
+ Salt and pepper developmental regression
1034
+ Sandestig-Stefanova
1035
+ Saul-Wilson
1036
+ Scalp-ear-nipple
1037
+ Scanner
1038
+ Scapuloperoneal
1039
+ Schaaf-Yang
1040
+ Schimmelpenning-Feuerstein-Mims
1041
+ Schinzel-Giedion
1042
+ Schinzel-Giedion midface retraction
1043
+ Schopf-Schulz-Passarge
1044
+ Schuurs-Hoeijmakers
1045
+ Schwartz-Jampel
1046
+ Scott
1047
+ Sd(a)
1048
+ Sd(a) polyagglutination
1049
+ Seckel
1050
+ Segawa
1051
+ Seizures
1052
+ Seizures, cortical blindness, microcephaly
1053
+ Seizures, scoliosis, and macrocephaly
1054
+ Sengers
1055
+ Senior-Loken
1056
+ Sessile
1057
+ Sessile serrated polyposis cancer
1058
+ Sezary
1059
+ Shaheen
1060
+ Shashi-Pena
1061
+ Short
1062
+ Short QT
1063
+ Short stature-micrognathia
1064
+ Shprintzen-Goldberg
1065
+ Shukla-Vernon
1066
+ Shwachman-Diamond
1067
+ Sick
1068
+ Sick sinus
1069
+ Siddiqi
1070
+ Sifrim-Hitz-Weiss
1071
+ Silver
1072
+ Silver spastic paraplegia
1073
+ Silver-Russell
1074
+ Simpson-Golabi-Behmel
1075
+ Singleton-Merten
1076
+ Sjogren-Larsson
1077
+ Skin
1078
+ Skin fragility-woolly hair
1079
+ Skraban-Deardorff
1080
+ Smith-Kingsmore
1081
+ Smith-Lemli-Opitz
1082
+ Smith-Magenis
1083
+ Sneddon
1084
+ Snijders
1085
+ Snijders Blok-Campeau
1086
+ Snijders Blok-Fisher
1087
+ Sotos
1088
+ Split-hand/foot
1089
+ Split-hand/foot malformation 3, gene duplication
1090
+ Spondylocarpotarsal
1091
+ Spondylocarpotarsal synostosis
1092
+ Spondyloocular
1093
+ Sprengel
1094
+ Stankiewicz-Isidor
1095
+ Steel
1096
+ Stevens-Johnson
1097
+ Stickler
1098
+ Stiff
1099
+ Stiff skin
1100
+ Stormorken
1101
+ Stromme
1102
+ Structural
1103
+ Structural heart defects and renal anomalies
1104
+ Sturge-Weber
1105
+ Stuve-Wiedemann
1106
+ Sudden
1107
+ Sudden infant death
1108
+ Sudden infant death with dysgenesis of the testes
1109
+ Suleiman-El-Hattab
1110
+ Supernumerary
1111
+ Supernumerary der(22)t(8-22)
1112
+ Sweeney-Cox
1113
+ TARP
1114
+ TSH
1115
+ Takenouchi-Kosaki
1116
+ Tarsal-carpal
1117
+ Tarsal-carpal coalition
1118
+ Tatton-Brown-Rahman
1119
+ Teebi
1120
+ Teebi hypertelorism
1121
+ Temple
1122
+ Temple-Baraitser
1123
+ Temtamy
1124
+ Temtamy preaxial brachydactyly
1125
+ Tenorio
1126
+ Tessadori-van
1127
+ Tessadori-van Haaften neurodevelopmental
1128
+ Tetra-amelia
1129
+ Tetraamelia
1130
+ Thauvin-Robinet-Faivre
1131
+ Thiamine
1132
+ Thiamine metabolism dysfunction
1133
+ Thiamine-responsive
1134
+ Thiamine-responsive megaloblastic anemia
1135
+ Thoracoabdominal
1136
+ Thrombocytopenia-absent
1137
+ Thrombocytopenia-absent radius
1138
+ Tietz
1139
+ Tietz albinism-deafness
1140
+ Timothy
1141
+ Tn
1142
+ Tn polyagglutination
1143
+ Tolchin-Le
1144
+ Tolchin-Le Caignec
1145
+ Tonne-Kalscheuer
1146
+ Tourette
1147
+ Townes-Brocks
1148
+ Townes-Brocks branchiootorenal-like
1149
+ Traboulsi
1150
+ Treacher
1151
+ Treacher Collins
1152
+ Treacher-Collins
1153
+ Trichodontoosseous
1154
+ Trichohepatoenteric
1155
+ Trichohepatoneurodevelopmental
1156
+ Trichorhinophalangeal
1157
+ Triokinase
1158
+ Triokinase and FMN cyclase deficiency
1159
+ Triphalangeal
1160
+ Triphalangeal thumb-polysyndactyly
1161
+ Trismus-pseudocamptodactyly
1162
+ Troyer
1163
+ Tukel
1164
+ Tumor
1165
+ Tumor predisposition
1166
+ Turner
1167
+ Turnpenny-Fry
1168
+ UV-sensitive
1169
+ Ulnar-mammary
1170
+ Uncombable
1171
+ Uncombable hair
1172
+ Urofacial
1173
+ Uruguay
1174
+ Uruguay faciocardiomusculoskeletal
1175
+ Usher
1176
+ Usmani-Riazuddin
1177
+ VBIH
1178
+ VEXAS
1179
+ VII
1180
+ VIII
1181
+ VISS
1182
+ Van
1183
+ Van Esch-O'Driscoll
1184
+ Van Maldergem
1185
+ Van den Ende-Gupta
1186
+ Vasculitis
1187
+ Vasculitis, autoinflammation, immunodeficiency, and hematologic defects
1188
+ Velocardiofacial
1189
+ Ventricular
1190
+ Ventricular arrhythmias due to cardiac ryanodine receptor calcium release deficiency
1191
+ Verheij
1192
+ Vertebral
1193
+ Vertebral, cardiac, renal, and limb defects
1194
+ Ververi-Brady
1195
+ Vici
1196
+ Vissers-Bodmer
1197
+ Vohwinkel
1198
+ Vulto-van
1199
+ Vulto-van Silfout-de Vries
1200
+ WAGRO
1201
+ WHIM
1202
+ Waardenburg
1203
+ Wagner
1204
+ Waisman
1205
+ Warburg
1206
+ Warburg micro
1207
+ Warburg-Cinotti
1208
+ Warsaw
1209
+ Warsaw breakage
1210
+ Watson
1211
+ Weaver
1212
+ Webb-Dattani
1213
+ Weill-Marchesani
1214
+ Weill-Marchesani 4
1215
+ Weiss-Kruszka
1216
+ Werner
1217
+ West
1218
+ White-Kernohan
1219
+ White-Sutton
1220
+ Wieacker-Wolff
1221
+ Wiedemann-Rautenstrauch
1222
+ Wiedemann-Steiner
1223
+ Williams
1224
+ Williams-Beuren
1225
+ Wilms
1226
+ Wilms tumor, aniridia, genitourinary anomalies and mental retardation
1227
+ Wilson-Turner
1228
+ Winchester
1229
+ Wiskott-Aldrich
1230
+ Witteveen-Kolk
1231
+ Wolcott-Rallison
1232
+ Wolf-Hirschhorn
1233
+ Wolff-Parkinson-White
1234
+ Wolfram
1235
+ Wolfram-like
1236
+ Woodhouse-Sakati
1237
+ Woods-Black-Norbury
1238
+ Wrinkly
1239
+ Wrinkly skin
1240
+ XFE
1241
+ XFE progeroid
1242
+ XI
1243
+ XII
1244
+ XII:c
1245
+ Xeroderma
1246
+ Xeroderma pigmentosum, group G/Cockayne
1247
+ Xeroderma pigmentosum, type F/Cockayne
1248
+ Xia-Gibbs
1249
+ Xp11.22
1250
+ Xp11.22 microduplication
1251
+ Xq21
1252
+ Xq21 deletion
1253
+ Xq25
1254
+ Xq25 duplication
1255
+ Yao
1256
+ Yoon-Bellen
1257
+ Yoon-Bellen neurodevelopmental
1258
+ You-Hoover-Fong
1259
+ Yuan-Harel-Lupski
1260
+ Yunis-Varon
1261
+ ZTTK
1262
+ Zaki
1263
+ Zimmermann-Laband
1264
+ a1
1265
+ a1 and b
1266
+ a10
1267
+ a3
1268
+ a4
1269
+ aarskog-scott
1270
+ abiotrophie
1271
+ abnormal
1272
+ abnormal hair
1273
+ abruzzo-erickson
1274
+ acampomelic campomelic
1275
+ acanthosis
1276
+ accelerated
1277
+ acetazolamide-responsive
1278
+ acetyl-coa
1279
+ achondrogenesis ib
1280
+ aciduria with
1281
+ acne
1282
+ acral punctate
1283
+ acrocapitofemoral
1284
+ acrochordon préauriculaire
1285
+ acrochordon périauriculaire
1286
+ acrodermatitis
1287
+ acrodysostosis
1288
+ acrofacial dysostosis
1289
+ acromegaloid
1290
+ acromicric
1291
+ acropectoral
1292
+ acropectorovertebral dysplasia
1293
+ acth-independent macronodular
1294
+ acth-secreting
1295
+ acute
1296
+ acute febrile
1297
+ acute lymphoblastic
1298
+ acute lymphoblastic leukemia
1299
+ acute myeloid
1300
+ acute nonlymphocytic
1301
+ acute promyelocytic
1302
+ acyl-coa
1303
+ acétabula
1304
+ adams-oliver
1305
+ adductor paralysis
1306
+ adelaide type
1307
+ adenine dinucleotide synthetase deficiency
1308
+ adenine phosphoribosyltransferase
1309
+ adenomatous polyposis
1310
+ adenosine
1311
+ adenosine deaminase
1312
+ adenosyltransferase i/iii
1313
+ adenylosuccinase
1314
+ adiponectin
1315
+ adrenal adenoma somatic
1316
+ adrenal hyperplasia
1317
+ adrenal hypoplasia
1318
+ adrenal insufficiency
1319
+ adrenocorticotropic
1320
+ adult
1321
+ adult onset
1322
+ adult-onset
1323
+ agammaglobulinemia
1324
+ agammaglobulinemia 8b
1325
+ agammaglobulinémie
1326
+ age-related cortical susceptibility to
1327
+ age-related hearing
1328
+ agenesis of
1329
+ aggrecan
1330
+ agnathia-otocephaly
1331
+ aiblesse
1332
+ aica-ribosiduria
1333
+ aicardi
1334
+ ain-naz
1335
+ akinesia
1336
+ al kaissi
1337
+ al-gazali
1338
+ al-gazali-bakalinova
1339
+ al-raqad
1340
+ alagille
1341
+ albinism with sensorineural deafness
1342
+ alcohol dependence
1343
+ alcohol-induced
1344
+ alexander disease
1345
+ alkaline
1346
+ alkuraya-kucinskas
1347
+ allan-herndon-dudley
1348
+ allergic
1349
+ allo-immunisation fœtomaternelle
1350
+ alopecia
1351
+ alopecia areata
1352
+ alpha-b crystallin-related
1353
+ alpha-fetoprotein
1354
+ alpha-methylacetoacetic aciduria
1355
+ alpha-methylacyl-coa racemase
1356
+ alpha-thalassemia myelodysplasia
1357
+ alpha-thalassemia/impaired
1358
+ alpha-thalassemia/mental retardation
1359
+ alport
1360
+ alstrom
1361
+ alternating hemiplegia
1362
+ alternating hemiplegia of childhood
1363
+ alveolar capillary dysplasia with misalignment
1364
+ alzahrani-kuwahara
1365
+ alzheimer disease-
1366
+ ambras
1367
+ amelogenesis
1368
+ amelogenesis imperfecta and skeletal
1369
+ amincissement choriorétinien
1370
+ amino-acidurie
1371
+ aminoacidurie
1372
+ aminoacidurie généralisée
1373
+ aminoacylase
1374
+ amish
1375
+ amorph
1376
+ amyotrophic lateral
1377
+ amyotrophic lateral sclerosis
1378
+ amyotrophic lateral sclerosis-parkinsonism/dementia
1379
+ anauxetic dysplasia
1380
+ and
1381
+ and acne
1382
+ and autistic features
1383
+ and autoimmunity
1384
+ and congenital heart defects
1385
+ and diabetes
1386
+ and enteropathy
1387
+ and episodic
1388
+ and genital
1389
+ and immunodeficiency
1390
+ and impaired
1391
+ and limb
1392
+ and myopia
1393
+ and nail
1394
+ and neurodegeneration
1395
+ and palmoplantar keratoderma
1396
+ and respiratory insufficiency
1397
+ and sclerosing
1398
+ and spasticity
1399
+ and symptomatic
1400
+ and testicular
1401
+ androgen
1402
+ anemie
1403
+ aneurysmal bone cysts
1404
+ angelman
1405
+ angiomatoid
1406
+ angiopathic
1407
+ angiotensin i-converting enzyme
1408
+ anisomastia
1409
+ ankyrin-b-related
1410
+ anneau de kayser-fleischer
1411
+ annular epidermolytic
1412
+ anomalie choriorétinienne
1413
+ anophtalmie
1414
+ anterior maxillary
1415
+ antibody deficiency
1416
+ antihélix anormal
1417
+ antithrombin iii
1418
+ antitragus
1419
+ antley-bixler
1420
+ aortic
1421
+ aortic valve disease
1422
+ apert
1423
+ aplasia cutis congenita
1424
+ aplastic
1425
+ apolipoprotein
1426
+ apolipoprotein c-iii
1427
+ apolipoprotein gene cluster deletion
1428
+ arboleda-tham
1429
+ argininosuccinic aciduria
1430
+ armfield
1431
+ arnold-chiari
1432
+ aromatic l-amino acid decarboxylase
1433
+ arrhythmogenic right ventricular
1434
+ arrhythmogenic right ventricular dysplasia
1435
+ arrhythmogenic right ventricular dysplasia with mild palmoplantar keratoderma and woolly hair
1436
+ arriérations mentales
1437
+ arthrite juvénile
1438
+ arthrochalasia
1439
+ arthrogrypose
1440
+ ary-épiglottiques
1441
+ aréflexie
1442
+ aspartate aminotransferase serum level of
1443
+ asperger
1444
+ aspirin-induced
1445
+ asthma
1446
+ asthma-related
1447
+ atad3 gene cluster
1448
+ ataxia-pancytopenia
1449
+ ataxia-telangiectasia
1450
+ ataxia-telangiectasia-like disorder
1451
+ atelis
1452
+ athabascan
1453
+ atresie biliaire
1454
+ atrioventricular septal
1455
+ atrioventricular septal defect
1456
+ atrophie choriorétinienne
1457
+ attenuated
1458
+ auditory
1459
+ auditory canal
1460
+ auditory neuropathy and optic
1461
+ auriculaire hypoplasique/petit
1462
+ auriculocondylar
1463
+ autoinflammatory
1464
+ autoinflammatory-pancytopenia
1465
+ avellino
1466
+ axillary
1467
+ b
1468
+ bachmann-bupp
1469
+ baker-gordon
1470
+ baller-gerold
1471
+ band
1472
+ bardet-biedl
1473
+ bart
1474
+ bart-pumphrey
1475
+ basan
1476
+ basilicata-akhtar
1477
+ bazex
1478
+ beaulieu-boycott-innes
1479
+ beck-fahrner
1480
+ becker
1481
+ beckwith-wiedemann
1482
+ behavioral abnormalities and neuropsychiatric
1483
+ bent bone dysplasia
1484
+ benzene toxicity
1485
+ bernard-soulier
1486
+ beta-2-adrenoreceptor
1487
+ bethlem myopathy
1488
+ bietti crystalline corneoretinal
1489
+ bilateral
1490
+ bilateral frontoparietal
1491
+ bilateral perisylvian
1492
+ biliary cirrhosis
1493
+ billuart
1494
+ biotin-responsive
1495
+ biotinidase deficiency
1496
+ birbeck
1497
+ birk-landau-perez
1498
+ bjornstad
1499
+ bladder
1500
+ bladder cancer
1501
+ blastome pleuropulmonaire
1502
+ blau
1503
+ blepharocheilodontic
1504
+ blomstrand
1505
+ bmiq11
1506
+ bombay
1507
+ bone marrow failure and diabetes mellitus
1508
+ boomerang
1509
+ bor-duane hydrocephalus
1510
+ borjeson-forssman-lehmann
1511
+ bornholm eye disease
1512
+ borochowitz-cormier-daire
1513
+ bosma arhinia microphthalmia
1514
+ bothnia retinal
1515
+ boucher-neuhauser
1516
+ brachydactyly-syndactyly
1517
+ brainstem dysgenesis
1518
+ branched-chain keto acid dehydrogenase kinase
1519
+ branchiootic
1520
+ breast
1521
+ breast cancer
1522
+ breast-ovarian
1523
+ brittle cornea
1524
+ brody
1525
+ brooke-spiegler
1526
+ brown-vialetto-van laere
1527
+ bruck
1528
+ brunet-wagner neurodevelopmental
1529
+ brunner
1530
+ buratti-harel
1531
+ burn scar-related
1532
+ burst-suppression
1533
+ buruli
1534
+ buschke-ollendorff
1535
+ butterfly-shaped
1536
+ butyrylcholinesterase deficiency
1537
+ c1s
1538
+ c2
1539
+ c7 deficiency
1540
+ cabezas
1541
+ caffey disease
1542
+ calcanéum
1543
+ calcific
1544
+ campomelic
1545
+ camptodactylie
1546
+ camptodactylie du majeur
1547
+ camptodactylie métacarpophalangienne
1548
+ camptodactylie partielle
1549
+ camptodactylie sévère
1550
+ camptodactyly
1551
+ camptodactyly-arthropathy-coxa vara-pericarditis
1552
+ camptothecin-resistant
1553
+ canal atrio-ventriculaire
1554
+ canal atrio-ventriculaire commun
1555
+ canal atrioventriculaire
1556
+ canal auriculoventriculaire
1557
+ canal carcinoma
1558
+ canal lacrymo-nasal
1559
+ canal vertébral
1560
+ canavan disease
1561
+ cap myopathy
1562
+ carbamazepine-induced
1563
+ carbamoylphosphate synthetase i deficiency
1564
+ carboxypeptidase
1565
+ carcinoma
1566
+ cardiac
1567
+ cardiac arrhythmia
1568
+ cardiac arrhythmias
1569
+ cardiac valvular
1570
+ cardiac valvular dysplasia
1571
+ cardiac-urogenital
1572
+ cardiofacioneurodevelopmental
1573
+ carey-fineman-ziter
1574
+ carnitine-acylcarnitine
1575
+ carotid intimal medial
1576
+ carotid intimal medial thickness
1577
+ carpal
1578
+ carpus curvus
1579
+ cataract
1580
+ catecholaminergic
1581
+ catel-manzke
1582
+ catifa
1583
+ catshl
1584
+ cayler cardiofacial
1585
+ cbla
1586
+ cblb
1587
+ cblf
1588
+ cblj
1589
+ cdags
1590
+ cebalid
1591
+ cenani-lenz syndactyly
1592
+ centronuclear
1593
+ centronuclear myopathy
1594
+ centrotemporal epilepsy
1595
+ cerebellar
1596
+ cerebellar ataxia
1597
+ cerebellar ataxia brain abnormalities and cardiac
1598
+ cerebellar ataxia deafness
1599
+ cerebellar ataxia neuropathy
1600
+ cerebellar atrophy with seizures and
1601
+ cerebellar hypoplasia
1602
+ cerebellar hypoplasia/atrophy epilepsy
1603
+ cerebral
1604
+ cerebral arteriopathy with subcortical infarcts and
1605
+ cerebral creatine deficiency
1606
+ cerebral dysgenesis
1607
+ cerebral-cerebellar-coloboma
1608
+ cerebrocostomandibular
1609
+ cerebrooculofacioskeletal
1610
+ cerebroretinal microangiopathy with calcifications and
1611
+ cerebroretinal microangiopathy with calcifications and cysts
1612
+ cerebrovascular
1613
+ cervical carcinoma
1614
+ chambre antérieure
1615
+ chanarin-dorfman
1616
+ chand
1617
+ charcot-marie-tooth
1618
+ charcot-marie-tooth disease
1619
+ charcot-marie-tooth disease axonal
1620
+ charcot-marie-tooth disease foot
1621
+ charles osborne
1622
+ charlevoix-saguenay
1623
+ chediak-higashi
1624
+ cheyne-stokes
1625
+ chilblain
1626
+ childhood
1627
+ childhood-onset
1628
+ childhood-onset stress-induced
1629
+ chitotriosidase
1630
+ cholestasis-lymphedema
1631
+ cholesteryl
1632
+ chondrodysplasie métaphysaire
1633
+ chopra-amiel-gordon
1634
+ chops
1635
+ choroid plexus
1636
+ choréo-athetoïdes
1637
+ choréo-athétose
1638
+ christ-siemens-touraine
1639
+ christianson
1640
+ chromosome 6pter-p24 deletion
1641
+ chung-jansen
1642
+ ciliary
1643
+ cinca
1644
+ cincinnati
1645
+ cisplatin-induced
1646
+ ck
1647
+ claes-jensen
1648
+ clapo
1649
+ claude bernard-horner
1650
+ cleft palate proliferative retinopathy and developmental
1651
+ cleft palate with
1652
+ clinodactylie
1653
+ clouston
1654
+ clumped
1655
+ clumsy
1656
+ cockayne
1657
+ cofactor ii
1658
+ cohen-gibson
1659
+ col du fémur
1660
+ colchicine
1661
+ colobome choriorétinien
1662
+ colobome choroïdien
1663
+ colobome de la paupière
1664
+ colobome de la paupière inférieure
1665
+ colobome irien
1666
+ colobome oculaire
1667
+ combined
1668
+ combined immunodeficiency and megaloblastic anemia with or
1669
+ combined immunodeficiency with microcephaly growth retardation
1670
+ compartement stéréotypique
1671
+ compton-north
1672
+ congenital
1673
+ congenital amaurosis
1674
+ congenital amegakaryocytic
1675
+ congenital anomalies-hypotonia-seizures
1676
+ congenital anomalies-neurodevelopmental
1677
+ congenital bilateral
1678
+ congenital cataract
1679
+ congenital cataracts
1680
+ congenital generalized
1681
+ congenital heart defects
1682
+ congenital myopathy with excess of muscle spindles
1683
+ congenital nuclear
1684
+ congenital short bowel
1685
+ congenital stationary
1686
+ congenital with brain and eye
1687
+ congenital with impaired
1688
+ congenital with inner ear
1689
+ congenital with structured cores
1690
+ congenital without impaired
1691
+ conotruncal anomaly
1692
+ conotruncal heart
1693
+ contractural arachnodactyly congenital
1694
+ coralliform
1695
+ corne ventrale
1696
+ cornelia de lange
1697
+ cornée
1698
+ coronary artery
1699
+ coronary artery disease
1700
+ cortex cérébral petit
1701
+ costo-chondrales
1702
+ coumarin resistance
1703
+ cpt ii
1704
+ cranioectodermal dysplasia
1705
+ craniofacial
1706
+ craniofacial-deafness-hand
1707
+ craniofacial-skeletal-dermatologic
1708
+ craniolenticulosutural
1709
+ craniometaphyseal
1710
+ craniosynostosis with radiohumeral
1711
+ creatine phosphokinase
1712
+ creutzfeldt-jakob
1713
+ creutzfeldt-jakob disease
1714
+ crigler-najjar
1715
+ crohn
1716
+ crohn disease
1717
+ crohn disease-associated growth
1718
+ crouzon
1719
+ cryohydrocytosis with neurologic
1720
+ crâniosynostose
1721
+ crâniosynostose prématurée
1722
+ culler-jones
1723
+ currarino
1724
+ curry-jones
1725
+ curth-macklin
1726
+ cystic fibrosis
1727
+ cystoid
1728
+ cysts 2a
1729
+ cytochrome-c oxydase
1730
+ czech
1731
+ céphaline
1732
+ d-glyceric aciduria
1733
+ dandy-walker
1734
+ danon
1735
+ darier
1736
+ davignon-chauveau
1737
+ ddb-negative subtype
1738
+ deafness autosomal recessive
1739
+ debrisoquine
1740
+ decreased urinary activity
1741
+ defaillance cardiaque
1742
+ dehydrated hereditary
1743
+ delpire-mcneill
1744
+ delta-beta thalassemia
1745
+ dentatorubral-pallidoluysian
1746
+ dentin
1747
+ dentinogenesis
1748
+ denys-drash
1749
+ dermatite exfoliatrice
1750
+ dermite
1751
+ desanto-shinawi
1752
+ desbuquois dysplasia
1753
+ desmoid disease
1754
+ developmental delay
1755
+ developmental delay with short stature
1756
+ di rocco
1757
+ diabète juvénile
1758
+ diamond blackfan
1759
+ diamond-blackfan
1760
+ diamètre antéro-postérieur
1761
+ diaphyseal medullary stenosis with malignant fibrous
1762
+ digenic
1763
+ digenic form
1764
+ digenic gjb2/
1765
+ dihydrolipoamide dehydrogenase
1766
+ dihydropyrimidine dehydrogenase
1767
+ dilated 1b
1768
+ dilated cardiomyopathy with woolly hair
1769
+ dimethylglycine dehydrogenase
1770
+ dimélie fibulaire
1771
+ disordered
1772
+ disordered steroidogenesis
1773
+ disseminated superficial actinic
1774
+ distichiasis
1775
+ dminnution
1776
+ donnai-barrow
1777
+ donohue
1778
+ dowling-degos
1779
+ doyne honeycomb degeneration of retina
1780
+ dravet
1781
+ drug
1782
+ drug-induced liver injury
1783
+ dubin-johnson
1784
+ ductus
1785
+ dursun
1786
+ dyschromatosis
1787
+ dyskeratosis
1788
+ dysostose mandibulo-faciale
1789
+ dysostosis
1790
+ dysostosis multiplex
1791
+ dysplasia progeroid
1792
+ dysplasia with congenital
1793
+ dyssegmental
1794
+ dystonia
1795
+ dystonia-parkinsonism
1796
+ dystrophie choriorétinienne
1797
+ dysérythropoïèse congénitale
1798
+ dégénérescence choriorétinienne progressive
1799
+ e55
1800
+ east texas
1801
+ ectodermal
1802
+ ectodermal dysplasia
1803
+ ectodermal dysplasia-syndactyly
1804
+ ectodermal dysplasia/short stature
1805
+ ectopia lentis
1806
+ edict
1807
+ eeg anormal
1808
+ electromyogramme anormal
1809
+ electrorétinogramme
1810
+ ellis-van creveld
1811
+ emg
1812
+ emphysema due to aat
1813
+ enamel-renal
1814
+ encephalopathy
1815
+ encephalopathy with neuropsychiatric features
1816
+ encéphalographie gazeuse
1817
+ endocrine-cerebroosteodysplasia
1818
+ endothelial
1819
+ enlarged vestibular
1820
+ enlarged vestibular aqueduct
1821
+ epicanthus
1822
+ epidermodysplasia
1823
+ epidermolytic hyperkeratosis
1824
+ epilépsie
1825
+ epiphyses
1826
+ episodic
1827
+ episodic kinesigenic dyskinesia
1828
+ erg aboli
1829
+ erg anormal
1830
+ erythrokeratodermia variabilis
1831
+ escobar
1832
+ esophageal
1833
+ estrogen
1834
+ ethylmalonic
1835
+ ewing
1836
+ exocrine pancreatic insufficiency
1837
+ extraoral halitosis
1838
+ exudative vitreoretinopathy
1839
+ f95 - tics
1840
+ fabry disease
1841
+ facial paresis
1842
+ facioscapulohumeral
1843
+ factor xi
1844
+ factor xiiia
1845
+ fanconi
1846
+ fanconi renotubular
1847
+ fascioscapulohumeral
1848
+ fast-channel
1849
+ fatty liver acute
1850
+ faundes-banka
1851
+ fazio-londe
1852
+ feingold
1853
+ female-limited
1854
+ female-specific]
1855
+ fente labio-palatine
1856
+ fente palatine submuqueuse
1857
+ fente palatine/labiale
1858
+ ferguson-bonni neurodevelopmental
1859
+ ferritinémie
1860
+ fetal
1861
+ fibrocalculous pancreatic
1862
+ fibromuscular
1863
+ fibrosis lung
1864
+ fibula rudimentaire
1865
+ finca
1866
+ finkel
1867
+ finnish
1868
+ fissure palatine
1869
+ fleck
1870
+ fleck retina
1871
+ fletcher factor
1872
+ follicular lymphoma
1873
+ fontaine progeroid
1874
+ fosse postérieure
1875
+ frank-ter haar
1876
+ fraser
1877
+ frasier
1878
+ freeman-sheldon
1879
+ french-canadian
1880
+ frias
1881
+ friedreich
1882
+ friedreich ataxia
1883
+ friedreich ataxia with retained
1884
+ frontotemporal
1885
+ frontotemporal dementia and/or
1886
+ frontotemporal lobar degeneration
1887
+ frontotemporal lobar degeneration with ubiquitin-positive
1888
+ fuchs
1889
+ fuhrmann
1890
+ fumarase deficiency
1891
+ fundus
1892
+ fémur
1893
+ galactokinase deficiency with
1894
+ galactosemia iv
1895
+ gand
1896
+ gapo
1897
+ gastric
1898
+ gastric adenocarcinoma and proximal polyposis of the
1899
+ gastrointestinale
1900
+ gelatinous drop-like
1901
+ geleophysic dysplasia
1902
+ geniospasm
1903
+ geroderma osteodysplasticum
1904
+ gerstmann-straussler disease
1905
+ gh-secreting
1906
+ giant axonal
1907
+ gilles de la tourette
1908
+ gillessen-kaesbach-nishimura
1909
+ gitelman
1910
+ glaucoma 1a
1911
+ glaucoma 1b
1912
+ glaucoma 1c
1913
+ glaucoma 1d primary open angle
1914
+ glaucoma 3a
1915
+ globoside
1916
+ glomerulopathy with fibronectin
1917
+ glomuvenous
1918
+ glomérulopathie
1919
+ glucocorticoid
1920
+ glucocorticoid-remediable
1921
+ glutaric acidemia
1922
+ glutaric acidemia iia
1923
+ glutaric aciduria iii
1924
+ glutathione synthetase
1925
+ glycerol
1926
+ glycine
1927
+ glycine encephalopathy with normal serum
1928
+ glycoprotein iv
1929
+ glycosylphosphatidylinositol
1930
+ glycosylphosphatidylinositol biosynthesis defect
1931
+ glyoxalase ii
1932
+ glénoïde hypoplasique
1933
+ goeminne tkcr
1934
+ goldberg-shprintzen megacolon
1935
+ gpapp
1936
+ graft-versus-host
1937
+ granulomatosis with polyangiitis
1938
+ gray platelet
1939
+ greenberg skeletal
1940
+ greig cephalopolysyndactyly
1941
+ griscelli
1942
+ guttmacher
1943
+ hackman-di donato
1944
+ hailey-hailey
1945
+ haim-munk
1946
+ hair
1947
+ hajdu-cheney
1948
+ halperin-birk
1949
+ hamamy
1950
+ hamartomas of tongue
1951
+ hardikar
1952
+ harel-yoon
1953
+ harp
1954
+ hartnup
1955
+ hartsfield
1956
+ hashimoto thyroiditis
1957
+ hearing
1958
+ heart block
1959
+ heimler
1960
+ helicobacter
1961
+ helsmoortel-van der aa
1962
+ hemihypertrophy
1963
+ hemolytic anemia
1964
+ hemolytic uremic
1965
+ hemophagocytic lymphohistiocytosis
1966
+ hemophilia
1967
+ hemophilia b
1968
+ hemorrhagic
1969
+ hemorrhagic diathesis
1970
+ hemorrhagic telangiectasia
1971
+ hengel-maroofian-schols
1972
+ hennekam lymphangiectasia-lymphedema
1973
+ hepatic
1974
+ hepatic adenoma somatic
1975
+ hepatic fibrosis susceptibility
1976
+ hepatocellular
1977
+ hepatorenocardiac degenerative
1978
+ hereditary
1979
+ hereditary benign
1980
+ hereditary benign intraepithelial
1981
+ hereditary congenital
1982
+ hereditary fibrosing
1983
+ hereditary hemorrhagic
1984
+ hereditary motor
1985
+ hereditary neuralgic
1986
+ hereditary sensory
1987
+ herpes-specific
1988
+ heyn-sproul-jackson
1989
+ hiatt-neu-cooper neurodevelopmental
1990
+ high
1991
+ hirschsprung
1992
+ hispanic gamma-delta-beta
1993
+ hiv
1994
+ hiv/aids
1995
+ hodgkin
1996
+ holocarboxylase synthetase deficiency
1997
+ holoprosencephaly
1998
+ holt-oram
1999
+ homocystinuria due to mthfr
2000
+ homocystinuria-megaloblastic
2001
+ homocystinurie
2002
+ hsd10
2003
+ humerofemoral hypoplasia with radiotibial ray
2004
+ hunter-thompson
2005
+ huntington
2006
+ huriez
2007
+ hutchinson-gilford
2008
+ hyaline fibromatosis
2009
+ hydatidiform
2010
+ hydranencephaly with abnormal genitalia
2011
+ hydro-uretère
2012
+ hydrocephalus with congenital
2013
+ hydrocephalus with hirschsprung
2014
+ hydrolethalus
2015
+ hygrome kystique
2016
+ hyperammoniémie légère
2017
+ hyperekplexie héréditaire
2018
+ hyperferritinemia-cataract
2019
+ hyperhidrosis palmaris
2020
+ hyperimmunoglobulin g1
2021
+ hyperinsulinism-hyperammonemia
2022
+ hyperkeratotic cutaneous capillary-venous
2023
+ hypermethioninemia with deficiency of
2024
+ hyperostosis
2025
+ hyperparathyroidism-jaw
2026
+ hyperphosphatasia with impaired intellectual development
2027
+ hyperplasia
2028
+ hyperplastic primary
2029
+ hyperréflexie
2030
+ hypersensitivity
2031
+ hypertonie
2032
+ hypertrichosis
2033
+ hypertrichotic osteochondrodysplasia
2034
+ hypertriglyceridemia
2035
+ hypertrophic
2036
+ hypocalciuric
2037
+ hypofonctionnement surrenal
2038
+ hypogonadotropic hypogonadism
2039
+ hypogonadotropic hypogonadism with
2040
+ hypogonadotropic hypogonadism with or
2041
+ hypogonadotropic hypogonadism with or without anosmia
2042
+ hypogonadotropic hypogonadism without
2043
+ hypohidrose
2044
+ hypohidrotic/hair/nail
2045
+ hypohidrotic/hair/tooth
2046
+ hypohidrotic/hair/tooth/nail
2047
+ hypokalemic tubulopathy and
2048
+ hypomimie
2049
+ hypomyelinating
2050
+ hypopigmentation
2051
+ hypopigmentation rétienne
2052
+ hypoplasie
2053
+ hypoplasie foetale
2054
+ hypoplasie glénoïdienne
2055
+ hypoplasie maxillaire légère
2056
+ hypoplasie maxillozygomatique
2057
+ hypoplasie médullosurrénalienne
2058
+ hypoplasie odontoïde
2059
+ hypoplasie olivo-ponto-cérébelleuse
2060
+ hypoplasie pontocérébelleuse
2061
+ hypoplastic
2062
+ hypoplastic left heart
2063
+ hypoplastic or aplastic tibia with
2064
+ hyporéflexie
2065
+ hyporéflexie/aréflexie
2066
+ hypotonia-cystinuria
2067
+ hypotrichosis-lymphedema-telangiectasia
2068
+ hypotrichosis-lymphedema-telangiectasia-renal defect
2069
+ ichthyosis
2070
+ ichthyosis prematurity
2071
+ igf1
2072
+ igg2
2073
+ ii
2074
+ iiic
2075
+ ikegawa
2076
+ imagawa-matsumoto
2077
+ imerslund-grasbeck
2078
+ immunodeficiency
2079
+ immunodeficiency 1a
2080
+ immunodeficiency 1b mycobacterial and viral
2081
+ immunodeficiency 3a with defective
2082
+ immunodeficiency 3b with defective
2083
+ immunodeficiency 3c with defective
2084
+ immunodeficiency 5a
2085
+ immunodeficiency 7a
2086
+ immunodeficiency 7b
2087
+ immunodeficiency and
2088
+ immunodeficiency and autoimmunity
2089
+ immunodeficiency and hyperinflammation
2090
+ immunodeficiency and hypertrophic
2091
+ immunodeficiency due to defect in
2092
+ immunodeficiency with
2093
+ immunodeficiency with autoimmunity and developmental
2094
+ immunodeficiency with hypogammaglobulinemia and
2095
+ immunodeficiency with pulmonary
2096
+ immunodeficiency with systemic
2097
+ immunodeficiency-centromeric instability-facial anomalies
2098
+ immunoglobulin
2099
+ immunoglobulin a deficiency
2100
+ immunoskeletal dysplasia with neurodevelopmental
2101
+ impaired
2102
+ impaired expressive language
2103
+ impaired intellectual
2104
+ impaired language and dysmorphic
2105
+ impaired language and gait
2106
+ impaired language epilepsy
2107
+ impaired responsiveness to
2108
+ impaired speech
2109
+ impdh2
2110
+ infantile cerebellar-retinal degeneration
2111
+ infantile onset
2112
+ infantile-onset
2113
+ infantile-onset multisystem
2114
+ infection-induced
2115
+ inflammatory
2116
+ inhibitor deficiency
2117
+ insulin resistance
2118
+ insulin resistance-related
2119
+ insulin-dependent
2120
+ insulin-dependent neonatal
2121
+ insulin-resistant
2122
+ interleukin-
2123
+ intervertebral
2124
+ intolerance
2125
+ intracranial berry
2126
+ intrahepatic
2127
+ intrapulmonaire récidivente
2128
+ isidor-toutain
2129
+ isolated congenital
2130
+ isovaleric acidemia
2131
+ iv
2132
+ ivic
2133
+ jackson-weiss
2134
+ jacobsen
2135
+ james
2136
+ jansen de vries
2137
+ john-milton-hagen
2138
+ joubert
2139
+ juberg-hayward
2140
+ junctional 1a
2141
+ junctional 1b
2142
+ junctional 2a
2143
+ junctional 2b
2144
+ junctional 2c
2145
+ junctional 3a
2146
+ junctional 3b
2147
+ junctional 5a
2148
+ junctional 5b
2149
+ juvenile myelomonocytic
2150
+ juvenile myoclonic
2151
+ juvenile recurrent
2152
+ juvenile-onset
2153
+ k25
2154
+ k42
2155
+ k65
2156
+ kaeser
2157
+ kallmann
2158
+ kantaputra type
2159
+ kanzaki
2160
+ keipert
2161
+ kenny-caffey
2162
+ keppen-lubinsky
2163
+ keratoconus
2164
+ keratoendothelitis fugax
2165
+ keratosis
2166
+ keutel
2167
+ khan-khan-katsanis
2168
+ kimberley
2169
+ kindler
2170
+ kininogen
2171
+ kininogène
2172
+ kleefstra
2173
+ klippel-feil
2174
+ klippel-trenaunay-weber
2175
+ knobloch
2176
+ knops
2177
+ kohlschutter-tonz
2178
+ kondoh
2179
+ kosaki overgrowth
2180
+ kowarski
2181
+ krabbe
2182
+ krakow
2183
+ kufor-rakeb
2184
+ kyphoscoliotic
2185
+ l-2-hydroxyglutaric aciduria
2186
+ l-ferritin
2187
+ l03 - phlegmon
2188
+ l50
2189
+ l68
2190
+ l83
2191
+ laing
2192
+ lambert
2193
+ laron dwarfism
2194
+ laurence-moon
2195
+ laurin-sandrow
2196
+ lchad
2197
+ legg-calve-perthes
2198
+ legius
2199
+ lenz-majewski hyperostotic
2200
+ leri pleonosteosis
2201
+ lesch-nyhan
2202
+ lessel-kubisch
2203
+ lethal congenital
2204
+ lethal congenital contractural
2205
+ leucoplasie buccale
2206
+ leukocyte
2207
+ leukoencephalopathy with dystonia and motor
2208
+ leukoplasie
2209
+ levy-shanske
2210
+ lewy
2211
+ leyden-moebius
2212
+ li-campeau
2213
+ li-ghorgani-weisz-hubshman
2214
+ liang-wang
2215
+ liddle
2216
+ lig4
2217
+ lipoma
2218
+ lipoprotein
2219
+ liposarcome myxoïde
2220
+ lipoyltransferase
2221
+ lissencephaly
2222
+ lissencephaly with cerebellar
2223
+ liver
2224
+ liver disease severe congenital
2225
+ lopes-maciel-rodan
2226
+ lowe
2227
+ lower extremity-predominant
2228
+ lowry-wood
2229
+ lumbar
2230
+ lung
2231
+ lung cancer
2232
+ lung disease
2233
+ luo-schoch-yamamoto
2234
+ lupus
2235
+ luscan-lumish
2236
+ luteinizing
2237
+ lutheran
2238
+ lymphangiectasie
2239
+ lymphangiectasie pulmonaire
2240
+ lymphangiome
2241
+ lymphatic
2242
+ lymphedema-distichiasis
2243
+ lymphoid hyperplasia and
2244
+ lynch
2245
+ lysinuric protein
2246
+ lysyl hydroxylase
2247
+ lèvre inférieure éversée
2248
+ légère splénomégalie
2249
+ léiomyome utérin
2250
+ m10 - goutte
2251
+ machado-joseph disease
2252
+ macrothrombocytopenia and granulocyte inclusions with or
2253
+ macular
2254
+ macular degeneration
2255
+ malan
2256
+ male
2257
+ male infertility
2258
+ malignant hyperthermia susceptibility
2259
+ mandibular
2260
+ mandibuloacral
2261
+ mandibulofacial dysostosis guion-almeida
2262
+ mandibulofacial dysostosis with
2263
+ manitoba
2264
+ mantle cell
2265
+ marbach-rustad progeroid
2266
+ marden-walker
2267
+ marfan
2268
+ marfan lipodystrophy
2269
+ marinesco-sjogren
2270
+ maroteaux-lamy
2271
+ marshall
2272
+ marshall-smith
2273
+ martin-probst
2274
+ masp2
2275
+ mast
2276
+ maxillary
2277
+ mcardle disease
2278
+ mccune-albright
2279
+ meacham
2280
+ mean
2281
+ meconium
2282
+ meconium ileus in cystic
2283
+ mednik
2284
+ meesmann
2285
+ meesmann corneal
2286
+ meester-loeys
2287
+ megacystis-microcolon-intestinal hypoperistalsis
2288
+ megaloblastic
2289
+ meier-gorlin
2290
+ melanocytic
2291
+ melanoma-pancreatic
2292
+ melkersson-rosenthal
2293
+ melnick-needles
2294
+ mend
2295
+ menke-hennekam
2296
+ menton
2297
+ merkel
2298
+ merosin
2299
+ merosin-positive
2300
+ mesomelic dysplasia
2301
+ metacarpal 4- fusion
2302
+ metachromatic
2303
+ metatarsus adductus
2304
+ metatropic
2305
+ methionine adenosyltransferase
2306
+ methylmalonate semialdehyde dehydrogenase
2307
+ methylmalonic aciduria
2308
+ methylmalonic aciduria and homocysteinemia cblx
2309
+ methylmalonic aciduria and homocystinuria
2310
+ methylmalonic aciduria and homocystinuria cbld
2311
+ mevalonic aciduria
2312
+ microcephalic osteodysplastic
2313
+ microcephaly
2314
+ microcephaly-micromelia
2315
+ microcoria
2316
+ micrognathie
2317
+ microsope
2318
+ microtia with nasolacrimal duct imperforation
2319
+ midface hypoplasia
2320
+ miller
2321
+ miller-dieker lissencephaly
2322
+ mineralocorticoid
2323
+ minicore myopathy with external
2324
+ missouri
2325
+ mitchell
2326
+ mitchell-riley
2327
+ moebius
2328
+ mohr-tranebjaerg
2329
+ molybdenum cofactor deficiency
2330
+ molybdenum cofactor deficiency b
2331
+ molybdenum cofactor deficiency c
2332
+ monocarboxylate
2333
+ monochromatisme
2334
+ morgagni-stewart-morel
2335
+ mowat-wilson
2336
+ mucoepithelial
2337
+ mucopolysaccharidosis
2338
+ mucopolysaccharidosis ih/s
2339
+ mucopolysaccharidosis ii
2340
+ mucopolysaccharidosis is
2341
+ mucopolysaccharidosis iva
2342
+ mucopolysaccharidosis vii
2343
+ muir-torre
2344
+ mulchandani-bhoj-conlin
2345
+ mullerian duct
2346
+ multicentric carpotarsal osteolysis
2347
+ multicentric osteolysis
2348
+ multinucleated
2349
+ multivitamin transporter
2350
+ mungan
2351
+ murk jansen
2352
+ musculocontractural
2353
+ musculoskeletal defects
2354
+ myasthenia gravis with thymus hyperplasia
2355
+ myasthenic
2356
+ myeloperoxidase deficiency
2357
+ myoclonic 2a
2358
+ myoclonic-atonic
2359
+ myoectodermal gonadal dysgenesis
2360
+ myofibrillar myopathy
2361
+ myogenic
2362
+ myokymies faciales
2363
+ myopathy
2364
+ myopathy with
2365
+ myopathy with early-onset paget disease with or without frontotemporal
2366
+ myopathy with early-onset paget disease without frontotemporal
2367
+ myopathy with fiber-type
2368
+ myopathy with lactic
2369
+ myopathy with lactic acidosis hereditary
2370
+ myopathy with myalgia
2371
+ myopia
2372
+ myopia-
2373
+ myopic
2374
+ myosin
2375
+ myotonia
2376
+ myotonia congenita
2377
+ myotonia congenita atypical
2378
+ myotonic
2379
+ myxoedème
2380
+ myxoid liposarcoma
2381
+ myélodysplasie hypoplasique
2382
+ méga-uretère
2383
+ mélanocytose
2384
+ métacarpien
2385
+ métacarpiens courts
2386
+ métaphyse tibiale
2387
+ métaphyse ulnaire
2388
+ métaphyses humérales
2389
+ n18
2390
+ nabais
2391
+ nablus mask-like facial
2392
+ nail-patella
2393
+ nanophthalmos
2394
+ nanophthalmos-
2395
+ narines antéversées
2396
+ narines hypoplasiques
2397
+ naxos disease
2398
+ nemaline myopathy
2399
+ neonatal
2400
+ neonatal severe
2401
+ nephropathy
2402
+ nestor-guillermo progeria
2403
+ neu-laxova
2404
+ neuroblastoma with hirschsprung
2405
+ neurocardiofaciodigital
2406
+ neurocognitive phenotype
2407
+ neurocutaneous melanosis
2408
+ neurodevelopmental
2409
+ neurodevelopmental delay
2410
+ neurodevelopmental-craniofacial
2411
+ neurofibromatosis-noonan
2412
+ neurogenic
2413
+ neurologic
2414
+ neurooculocardiogenitourinary
2415
+ neurosensoriel congénital
2416
+ neutrophilic dermatosis
2417
+ nevi flammei
2418
+ newfoundland rod-cone
2419
+ nicolaides-baraitser
2420
+ nijmegen breakage
2421
+ nivelon-nivelon-mabille
2422
+ nizon-isidor
2423
+ nonaka
2424
+ nonerythroid
2425
+ nongoitrous
2426
+ nonimmune chronic
2427
+ noninsulin-dependent
2428
+ noninsulin-dependent late
2429
+ nonspecific
2430
+ noonan
2431
+ nor polyagglutination
2432
+ norman-roberts
2433
+ north carolina
2434
+ northern epilepsy
2435
+ nystagmus
2436
+ nævus simplex
2437
+ néphrolithiase oxalique
2438
+ néphrolithiase oxalo-calcique
2439
+ néphrolithiase oxalocalcique
2440
+ néphronophthise juvénile
2441
+ occiput
2442
+ ocular
2443
+ oculocutaneous
2444
+ oculogastrointestinal neurodevelopmental
2445
+ oculomotor apraxia
2446
+ odontochondrodysplasia
2447
+ of pregnancy
2448
+ ogden
2449
+ oguchi
2450
+ ohdo
2451
+ okt4 epitope
2452
+ okur-chung neurodevelopmental
2453
+ oligodontia-colorectal cancer
2454
+ oliver-mcfarlane
2455
+ olmsted
2456
+ omphalocele
2457
+ onychodysplasie
2458
+ opitz-kaveggia
2459
+ ornithine transcarbamylase deficiency
2460
+ orofaciodigital
2461
+ osteogenesis
2462
+ osteoglophonic
2463
+ osteosclerotic metaphyseal
2464
+ otopalatodigital
2465
+ otospondylomegaepiphyseal
2466
+ ovarian
2467
+ ovarian carcinoma
2468
+ ovarian dysgenesis
2469
+ oxoglutarate dehydrogenase
2470
+ oxycéphalie
2471
+ p1pk
2472
+ pachyonychia congenita
2473
+ paganini-miozzo
2474
+ palais haut
2475
+ palais hypoplasique
2476
+ pallister-hall
2477
+ pallister-hall-like
2478
+ palmo-plantaire
2479
+ palmoplantar
2480
+ palmoplantar hyperkeratosis
2481
+ palmoplantar hyperkeratosis with squamous cell
2482
+ palmoplantar keratoderma and woolly hair
2483
+ palmoplantar keratoderma nagashima
2484
+ palmoplantar keratoderma with congenital
2485
+ pancreatic
2486
+ pancreatic agenesis
2487
+ pancreatic agenesis and congenital heart defects
2488
+ pancreatic and cerebellar
2489
+ pancreatic cancer
2490
+ pancreatic carcinoma somatic
2491
+ pancreatic lipase
2492
+ papillon-lefevre
2493
+ papillorenal
2494
+ paragangliomas
2495
+ paramyotonia congenita
2496
+ paraparésie
2497
+ parastremmatic dwarfism
2498
+ parathyroid
2499
+ parathyroid adenoma
2500
+ parathyroid adenoma with cystic
2501
+ parenti-mignot neurodevelopmental
2502
+ parietal foramina
2503
+ parietal foramina with cleidocranial
2504
+ parkinson
2505
+ parkinson disease
2506
+ parkinsonism-dystonia infantile
2507
+ paroxysmal extreme pain
2508
+ paroxysmal nocturnal hemoglobinuria
2509
+ paroxysmal nonkinesigenic
2510
+ paroxysmal nonkinesigenic dyskinesia
2511
+ pcwh
2512
+ peho
2513
+ pelger-huet
2514
+ pelger-huët
2515
+ pelizaeus-merzbacher
2516
+ pelvic organ
2517
+ pendred
2518
+ penttinen
2519
+ pepck deficiency
2520
+ perinatal lethal
2521
+ periodontitis
2522
+ peripheral
2523
+ peripheral arterial
2524
+ peripheral neuropathy with
2525
+ periventricular heterotopia with microcephaly
2526
+ periventricular nodular heterotopia
2527
+ perlman
2528
+ peroxisomal acyl-coa oxidase
2529
+ peroxisomal fatty acyl-coa
2530
+ peroxisome biogenesis
2531
+ peroxisome biogenesis disorder 0a
2532
+ peroxisome biogenesis disorder 1a
2533
+ peroxisome biogenesis disorder 2a
2534
+ peroxisome biogenesis disorder 3a
2535
+ peroxisome biogenesis disorder 6a
2536
+ peroxisome biogenesis disorder 7a
2537
+ perrault
2538
+ perry
2539
+ pettigrew
2540
+ phalanges
2541
+ phelan-mcdermid
2542
+ philtrum
2543
+ phosphoenolpyruvate carboxykinase
2544
+ phosphoglycerate dehydrogenase
2545
+ phosphoribosylaminoimidazole carboxylase
2546
+ phosphoribosylpyrophosphate synthetase superactivity
2547
+ phosphorylase
2548
+ phosphoserine aminotransferase
2549
+ pierpont
2550
+ pierre robin
2551
+ pierson
2552
+ pigmented nodular adrenocortical
2553
+ pigmented paravenous chorioretinal
2554
+ pilarowski-bjornsson
2555
+ pitt-hopkins
2556
+ pitt-hopkins like
2557
+ pitt-hopkins-like
2558
+ pituitary
2559
+ pituitary adenoma
2560
+ pituitary adenoma acth-secreting
2561
+ pityriasis rubra
2562
+ pl2f/rara
2563
+ placental abruption
2564
+ plantaris
2565
+ plasminogen
2566
+ platyspondylic skeletal
2567
+ pleuropulmonary
2568
+ pml/rara
2569
+ pneumopnie
2570
+ poikiloderma with
2571
+ poirier-bienvenu neurodevelopmental
2572
+ poly)pointe-ondes
2573
+ polyarthrite rhumatoïde
2574
+ polycystic kidney disease
2575
+ polycystic kidney disease infantile severe
2576
+ polycystic kidney disease with or without polycystic liver disease
2577
+ polycystic lipomembranous osteodysplasia with sclerosing
2578
+ polycystic liver disease
2579
+ polycystic liver disease with or without kidney
2580
+ polycystic ovary
2581
+ pontocerebellar
2582
+ pontocerebellar hypoplasia
2583
+ popliteal
2584
+ poretti-boltshauser
2585
+ porphyria
2586
+ porphyria cutanea
2587
+ potocki-lupski
2588
+ potocki-shaffer
2589
+ prader-willi
2590
+ preauricular fistulae
2591
+ preauricular sinus
2592
+ preauricular tag
2593
+ preaxial i
2594
+ pregnancy
2595
+ pregnancy-induced
2596
+ preterm premature rupture of the
2597
+ primary closed-angle
2598
+ primary sclerosing
2599
+ primordial dwarfism-immunodeficiency-lipodystrophy
2600
+ primrose
2601
+ progeroid
2602
+ progressiva
2603
+ prolidase deficiency
2604
+ proliferative vasculopathy and hydranencephaly-hydrocephaly
2605
+ properdin
2606
+ prune belly
2607
+ pseudoautosomal
2608
+ pseudofolliculitis
2609
+ pseudohypoaldosteronism
2610
+ pseudohypoparathyroidism ia
2611
+ pseudohypoparathyroidism ib
2612
+ pseudohypoparathyroidism ic
2613
+ pseudotumeur molluscoïde
2614
+ pseudovaginal perineoscrotal
2615
+ pseudoxanthoma
2616
+ pseudoxanthoma elasticum-like disorder with
2617
+ psoriatic
2618
+ pterygium colli
2619
+ pulmonary
2620
+ pulmonary alveolar microlithiasis
2621
+ punctal pits
2622
+ punctate type ia
2623
+ punctate type ib
2624
+ pyle
2625
+ pyloric stenosis
2626
+ pyloric stenosis infantile
2627
+ pyogenic sterile arthritis
2628
+ pyogènes
2629
+ pyridoxamine -phosphate
2630
+ pyridoxine-dependent
2631
+ pyridoxine-refractory
2632
+ pyruvate dehydrogenase
2633
+ pyruvate dehydrogenase e1-beta
2634
+ pyruvate dehydrogenase e2
2635
+ pyruvate dehydrogenase phosphatase
2636
+ qtl5
2637
+ quadriparésie
2638
+ r51 - céphalée
2639
+ r61 - hyperhidrose
2640
+ rabin-pappas
2641
+ radioulnar synostosis
2642
+ radioulnar synostosis with amegakaryocytic thrombocytopenia
2643
+ radius incurvé
2644
+ rafiq
2645
+ rahman
2646
+ raine
2647
+ rapadilino
2648
+ rapp-hodgkin
2649
+ rauch-steindl
2650
+ raymond
2651
+ recombination rate
2652
+ refsum
2653
+ renal agenesis
2654
+ renal and limb
2655
+ renal and limb defects
2656
+ renal-hepatic-pancreatic dysplasia
2657
+ renpenning
2658
+ respiratory insufficiency
2659
+ respiratory insufficiency and brain
2660
+ respiratory papillomatosis
2661
+ reticular dysgenesis
2662
+ retinal arterial macroaneurysm with supravalvular pulmonic stenosis
2663
+ retinal cone dystrophy
2664
+ retinal degeneration late-onset
2665
+ rett
2666
+ revesz
2667
+ reynolds
2668
+ rh-induced
2669
+ rh-null
2670
+ rhabdoid
2671
+ rhabdomyosarcoma
2672
+ riboflavin
2673
+ riboflavin-responsive
2674
+ riddle
2675
+ rieger
2676
+ ritscher-schinzel
2677
+ robinow
2678
+ robinow-sorauf
2679
+ roifman
2680
+ roifman-chitayat
2681
+ rosah
2682
+ roussy-levy
2683
+ rubinstein-taybi
2684
+ ruijs-aalfs
2685
+ sacral agenesis with vertebral
2686
+ saethre-chotzen
2687
+ salih myopathy
2688
+ salla disease
2689
+ salt-sensitive
2690
+ sandestig-stefanova
2691
+ sandhoff disease infantile
2692
+ sanfilippo
2693
+ saul-wilson
2694
+ sbbyss
2695
+ scapula
2696
+ scapulo-péronière progressive
2697
+ scapuloperoneal
2698
+ schimke immunoosseous
2699
+ schistosoma mansoni
2700
+ schmid
2701
+ schneckenbecken
2702
+ schnyder
2703
+ schopf-schulz-passarge
2704
+ schuurs-hoeijmakers
2705
+ scid
2706
+ sclerosteosis
2707
+ scott
2708
+ scrotum
2709
+ scurvy
2710
+ secretory
2711
+ secretory chloride
2712
+ sensorineural deafness
2713
+ sensorineural hearing
2714
+ sensorineural hearing loss
2715
+ septooptic
2716
+ serkal
2717
+ sessile serrated
2718
+ severe
2719
+ severe congenital
2720
+ severe cytomegalovirus
2721
+ shaheen
2722
+ sheldon-hall
2723
+ short stature
2724
+ short-rib thoracic dysplasia
2725
+ short-rib thoracic dysplasia with
2726
+ short-rib thoracic dysplasia with or
2727
+ short-rib thoracic dysplasia without
2728
+ shprintzen-goldberg
2729
+ shukla-vernon
2730
+ shwachman-diamond
2731
+ sick sinus
2732
+ siddiqi
2733
+ siderius
2734
+ silver spastic paraplegia
2735
+ silver-russell
2736
+ silverman-handmaker
2737
+ simha
2738
+ sinus pilonidal
2739
+ sinus préauriculaire
2740
+ skeletal
2741
+ sleepwalking type
2742
+ slowed
2743
+ smed strudwick
2744
+ smith-kingsmore
2745
+ smith-lemli-opitz
2746
+ smith-magenis
2747
+ smith-mccort
2748
+ sneddon
2749
+ snijders blok-campeau
2750
+ snijders blok-fisher
2751
+ somatic
2752
+ somatic mosaic
2753
+ sorbitol dehydrogenase deficiency with peripheral
2754
+ sotos
2755
+ sourcils
2756
+ spahr
2757
+ spastic
2758
+ spastic ataxia
2759
+ spastic paralysis
2760
+ spastic paraparesis
2761
+ spastic paraplegia
2762
+ spastic paraplegia and psychomotor retardation
2763
+ spastic quadriplegia
2764
+ spastic quadriplegic
2765
+ spastic tetraplegia
2766
+ spastic tetraplegia and axial hypotonia progressive
2767
+ specific
2768
+ spermatocytic seminoma
2769
+ spermatogenic
2770
+ spermatogenic failure
2771
+ spheroid
2772
+ spinocerebellar
2773
+ spinocerebellar ataxia
2774
+ spondylocostal dysostosis
2775
+ spondylodysplastic
2776
+ spondyloepimetaphyseal
2777
+ squalene
2778
+ stankiewicz-isidor
2779
+ stapes ankylosis with broad thumbs and toes
2780
+ stein-leventhal
2781
+ steiner
2782
+ stevens-johnson
2783
+ stevenson cutis gyrata
2784
+ stocco dos santos
2785
+ striatal
2786
+ striatonigral degeneration
2787
+ stromme
2788
+ sturge-weber
2789
+ stuve-wiedemann
2790
+ subcortical laminal heterotopia
2791
+ subcortical laminar heterotopia
2792
+ subependymal
2793
+ succinic semialdehyde dehydrogenase
2794
+ succinyl coa:3-oxoacid coa transferase deficiency
2795
+ sudden
2796
+ sudden cardiac
2797
+ suleiman-el-hattab
2798
+ superoxide
2799
+ supravalvar aortic stenosis
2800
+ symoens-barnes-gistelinck
2801
+ syndrome-
2802
+ synostose astragalo-calcanéenne
2803
+ synostose astragalocalcanéenne
2804
+ synostose carpienne
2805
+ synostose carpométacarpienne
2806
+ synostose huméroradiale
2807
+ synostose métacarpienne
2808
+ synostose métacarpo-phalangienne
2809
+ synostose métacarpophalangienne
2810
+ synostose métatarsienne
2811
+ synostose scapulo-humérale
2812
+ synostose talocalcanéenne
2813
+ synostose tarsiennne
2814
+ synpolydactyly
2815
+ synthetase deficiency
2816
+ t4 basse
2817
+ t68 - hypothermie
2818
+ takenouchi-kosaki
2819
+ tangier disease
2820
+ tarsal-carpal coalition
2821
+ tateyama
2822
+ tcr-alpha/beta deficient
2823
+ teebi hypertelorism
2824
+ telomere length
2825
+ temple-baraitser
2826
+ tenorio
2827
+ tessadori-van haaften neurodevelopmental
2828
+ testicular
2829
+ testicular anomalies with or without congenital heart disease
2830
+ tetra-amelia
2831
+ tetraamelia
2832
+ tetrasomy 8p
2833
+ thauvin-robinet-faivre
2834
+ thiel-behnke
2835
+ thrombocythemia
2836
+ thrombocytopenia with
2837
+ thrombophilia
2838
+ thrombotic thrombocytopenic
2839
+ thyrotoxic periodic paralysis
2840
+ tietz albinism-deafness
2841
+ timothy
2842
+ to antithrombin pittsburgh
2843
+ tolbutamide poor metabolizer
2844
+ torrance
2845
+ townes-brocks
2846
+ townes-brocks branchiootorenal-like
2847
+ transcobalamin ii
2848
+ treacher collins
2849
+ treacher-collins
2850
+ trehalase
2851
+ trichiase
2852
+ trichilemmal cyst
2853
+ trichothiodystrophy
2854
+ troyer
2855
+ tsc2 angiomyolipomas
2856
+ tuberculosis
2857
+ turner
2858
+ tylosis with esophageal
2859
+ ullrich congenital
2860
+ uncombable hair
2861
+ uretère double
2862
+ uric
2863
+ uridine-cytidineuria]
2864
+ urocanase deficiency
2865
+ uruguay
2866
+ usher
2867
+ usmani-riazuddin
2868
+ valve mitrale
2869
+ valve pulmonaire
2870
+ van
2871
+ van buchem
2872
+ van buchem disease
2873
+ van den ende-gupta
2874
+ van der Woude
2875
+ van der woude
2876
+ van esch-odriscoll
2877
+ van maldergem
2878
+ vascular
2879
+ vascular disease
2880
+ vasculite
2881
+ vasovagal
2882
+ velocardiofacial
2883
+ venous
2884
+ ventricular
2885
+ ventricular arrhythmias
2886
+ ventricular septal defect
2887
+ ventriculomegaly with cystic kidney disease
2888
+ verheij
2889
+ vertebral
2890
+ vesicoureteral
2891
+ vessie neurogène
2892
+ vestibulo-oculaire anormal
2893
+ vestibulocerebellar disorder with predominant ocular signs
2894
+ vexas
2895
+ vibratory
2896
+ visceral
2897
+ visceral myopathy
2898
+ vissers-bodmer
2899
+ vitreoretinopathy with phalangeal epiphyseal
2900
+ vlcad
2901
+ von
2902
+ von Hippel-Lindau
2903
+ von hippel-lindau
2904
+ vries
2905
+ vulto-van silfout-de vries
2906
+ vésico-urétéral
2907
+ vésico-urétéro-rénal
2908
+ waardenburg
2909
+ wagner
2910
+ waisman
2911
+ warfarin
2912
+ warsaw breakage
2913
+ watson
2914
+ weaver
2915
+ weiss-kruszka
2916
+ welander
2917
+ werner
2918
+ white sponge
2919
+ white-kernohan
2920
+ white-sutton
2921
+ willebrand
2922
+ williams-beuren
2923
+ wilson disease
2924
+ wilson-turner
2925
+ winchester
2926
+ wiskott-aldrich
2927
+ with
2928
+ with 6xy sex
2929
+ with abnormal
2930
+ with acanthosis
2931
+ with amelogenesis
2932
+ with ataxia
2933
+ with atrichia and photophobia
2934
+ with autoimmunity
2935
+ with bartter
2936
+ with brachydactyly
2937
+ with cerebellar
2938
+ with cerebellar hypoplasia and cortical
2939
+ with cerebral leukoencephalopathy and systemic manifestations
2940
+ with chromosomal instability somatic
2941
+ with cochlear aplasia
2942
+ with congenital
2943
+ with congenital cataract and developmental
2944
+ with deafness
2945
+ with developmental
2946
+ with episodic
2947
+ with gingival hyperplasia
2948
+ with heterotaxy
2949
+ with hypercalciuric
2950
+ with hyperglycinemia
2951
+ with hypertrophic
2952
+ with hypomyelinating
2953
+ with impaired intellectual
2954
+ with impaired proprioception and touch
2955
+ with impaired pupillary
2956
+ with juvenile macular
2957
+ with limb
2958
+ with male infertility
2959
+ with microcephaly
2960
+ with microcornea
2961
+ with microvillus
2962
+ with migratory circinate
2963
+ with minicore
2964
+ with multisystem
2965
+ with myopathy and facial
2966
+ with neonatal respiratory
2967
+ with neurodevelopmental
2968
+ with neuropsychiatric features and
2969
+ with neuroserpin
2970
+ with oculomotor apraxia and hypoalbuminemia
2971
+ with palmoplantar
2972
+ with paroxysmal
2973
+ with peripheral neuropathy
2974
+ with pyloric
2975
+ with pyloric atresia
2976
+ with respiratory insufficiency and bone
2977
+ with skeletal
2978
+ with spastic
2979
+ with spasticity and tapetoretinal degeneration
2980
+ with subcortical infarcts and
2981
+ with tufting enteropathy congenital
2982
+ with woolly hair and
2983
+ witkop
2984
+ witteveen-kolk
2985
+ wolcott-rallison
2986
+ wolman disease
2987
+ x-linked
2988
+ xeroderma
2989
+ xia-gibbs
2990
+ xv
2991
+ yoon-bellen neurodevelopmental
2992
+ yuan-harel-lupski
2993
+ yunis-varon
2994
+ zimmermann-laband
2995
+ zollinger-ellison
2996
+ épiphysite vertébrale
2997
+ épithélioma baso-cellulaire
2998
+ état
data/hp_fr_en_translated_marian_review_lwg.json ADDED
The diff for this file is too large to render. See raw diff
 
img/CHU-montpellier.png ADDED
img/logo.png ADDED
img/logosfacmontpellier.png ADDED
lf_app.py ADDED
@@ -0,0 +1,664 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ from __future__ import annotations # For Python 3.7
2
+ import streamlit as st
3
+ from PIL import Image
4
+ import pandas as pd
5
+ import re
6
+ import json
7
+ import nltk
8
+ import stanza
9
+ from dataclasses import dataclass
10
+ from typing import List
11
+ import transformers
12
+ from typing import Sequence
13
+ import spacy
14
+ from presidio_analyzer import AnalyzerEngine, RecognizerRegistry
15
+ from presidio_analyzer.nlp_engine import NlpEngineProvider
16
+ from presidio_anonymizer import AnonymizerEngine
17
+ from presidio_anonymizer.entities import RecognizerResult, OperatorConfig
18
+ import subprocess
19
+
20
+ # -- Set page config
21
+ apptitle = "Linguo Franca"
22
+
23
+ st.set_page_config(page_title=apptitle, page_icon=":incoming_envelope:", layout="wide")
24
+
25
+ # -- Set Sidebar
26
+ image_pg = Image.open("img/logo_300x.png")
27
+ st.sidebar.image(image_pg, caption=None, width=200)
28
+ st.sidebar.title("Linguo Franca")
29
+
30
+ st.sidebar.header(
31
+ "Share medical consultation letter automatically translated, de-identified and summarized using deep learning"
32
+ )
33
+
34
+ st.sidebar.markdown(
35
+ """
36
+ If any questions or suggestions, please contact: [kevin.yauy@chu-montpellier.fr](kevin.yauy@chu-montpellier.fr) and [lucas.gauthier@chu-lyon.fr](lucas.gauthier@chu-lyon.fr)
37
+
38
+ Code source is available in GitHub:
39
+ [https://github.com/kyauy/Linguo-Franca](https://github.com/kyauy/Linguo-Franca)
40
+
41
+ Linguo Franca is an initiative from:
42
+ """
43
+ )
44
+ image_univ = Image.open("img/logosfacmontpellier.png")
45
+ st.sidebar.image(image_univ, caption=None, width=190)
46
+
47
+ image_chu = Image.open("img/CHU-montpellier.png")
48
+ st.sidebar.image(image_chu, caption=None, width=95)
49
+
50
+
51
+ @st.cache_resource()
52
+ def get_models():
53
+ nltk.download("omw-1.4")
54
+ stanza.download("fr")
55
+ spacy_model_name = "en_core_web_lg"
56
+ if not spacy.util.is_package(spacy_model_name):
57
+ spacy.cli.download(spacy_model_name)
58
+ else:
59
+ print(spacy_model_name + " already downloaded")
60
+ return "Done"
61
+
62
+
63
+ @st.cache_data()
64
+ def get_list_not_deidentify():
65
+ nom_propre_data = pd.read_csv(
66
+ "data/exception_list_anonymization.tsv", sep="\t", header=None
67
+ )
68
+ nom_propre_list = nom_propre_data[0].to_list() + [
69
+ "PN",
70
+ "TN",
71
+ "SD",
72
+ "PCN",
73
+ "cher",
74
+ "chere",
75
+ "CAS",
76
+ "INDEX",
77
+ ]
78
+ nom_propre = [x.lower() for x in nom_propre_list]
79
+ return nom_propre
80
+
81
+
82
+ @st.cache_resource()
83
+ def config_deidentify():
84
+ configuration = {
85
+ "nlp_engine_name": "spacy",
86
+ "models": [{"lang_code": "en", "model_name": "en_core_web_lg"}],
87
+ }
88
+
89
+ # Create NLP engine based on configuration
90
+ provider = NlpEngineProvider(nlp_configuration=configuration)
91
+ nlp_engine = provider.create_engine()
92
+
93
+ analyzer = AnalyzerEngine(nlp_engine=nlp_engine, supported_languages=["en"])
94
+ engine = AnonymizerEngine()
95
+ return analyzer, engine
96
+
97
+
98
+ @st.cache_resource()
99
+ def get_nlp_marian():
100
+ nlp = stanza.Pipeline("fr", processors="tokenize")
101
+ marian_fr_en = Translator("fr", "en")
102
+ return nlp, marian_fr_en
103
+
104
+
105
+ @dataclass(frozen=True)
106
+ class SentenceBoundary:
107
+ text: str
108
+ prefix: str
109
+
110
+ def __str__(self):
111
+ return self.prefix + self.text
112
+
113
+
114
+ @dataclass(frozen=True)
115
+ class SentenceBoundaries:
116
+ sentence_boundaries: List[SentenceBoundary]
117
+
118
+ @classmethod
119
+ def from_doc(cls, doc: stanza.Document) -> SentenceBoundaries:
120
+ sentence_boundaries = []
121
+ start_idx = 0
122
+ for sent in doc.sentences:
123
+ sentence_boundaries.append(
124
+ SentenceBoundary(
125
+ text=sent.text,
126
+ prefix=doc.text[start_idx : sent.tokens[0].start_char],
127
+ )
128
+ )
129
+ start_idx = sent.tokens[-1].end_char
130
+ sentence_boundaries.append(
131
+ SentenceBoundary(text="", prefix=doc.text[start_idx:])
132
+ )
133
+ return cls(sentence_boundaries)
134
+
135
+ @property
136
+ def nonempty_sentences(self) -> List[str]:
137
+ return [item.text for item in self.sentence_boundaries if item.text]
138
+
139
+ def map(self, d: dict[str, str]) -> SentenceBoundaries:
140
+ return SentenceBoundaries(
141
+ [
142
+ SentenceBoundary(text=d.get(sb.text, sb.text), prefix=sb.prefix)
143
+ for sb in self.sentence_boundaries
144
+ ]
145
+ )
146
+
147
+ def __str__(self) -> str:
148
+ return "".join(map(str, self.sentence_boundaries))
149
+
150
+
151
+ def minibatch(seq, size):
152
+ items = []
153
+ for x in seq:
154
+ items.append(x)
155
+ if len(items) >= size:
156
+ yield items
157
+ items = []
158
+ if items:
159
+ yield items
160
+
161
+
162
+ # @dataclass(frozen=True)
163
+ class Translator:
164
+ def __init__(self, source_lang: str, dest_lang: str, use_gpu: bool = False) -> None:
165
+ # self.use_gpu = use_gpu
166
+ self.model_name = "Helsinki-NLP/opus-mt-" + source_lang + "-" + dest_lang
167
+ self.model = transformers.MarianMTModel.from_pretrained(self.model_name)
168
+ # if use_gpu:
169
+ # self.model = self.model.cuda()
170
+ self.tokenizer = transformers.MarianTokenizer.from_pretrained(self.model_name)
171
+ self.sentencizer = stanza.Pipeline(
172
+ source_lang, processors="tokenize", verbose=False, use_gpu=use_gpu
173
+ )
174
+
175
+ def sentencize(self, texts: Sequence[str]) -> List[SentenceBoundaries]:
176
+ return [
177
+ SentenceBoundaries.from_doc(self.sentencizer.process(text))
178
+ for text in texts
179
+ ]
180
+
181
+ def translate(
182
+ self, texts: Sequence[str], batch_size: int = 10, truncation=True
183
+ ) -> Sequence[str]:
184
+ if isinstance(texts, str):
185
+ raise ValueError("Expected a sequence of texts")
186
+ text_sentences = self.sentencize(texts)
187
+ translations = {
188
+ sent: None for text in text_sentences for sent in text.nonempty_sentences
189
+ }
190
+
191
+ for text_batch in minibatch(
192
+ sorted(translations, key=len, reverse=True), batch_size
193
+ ):
194
+ tokens = self.tokenizer(
195
+ text_batch, return_tensors="pt", padding=True, truncation=truncation
196
+ )
197
+ # if self.use_gpu:
198
+ # tokens = {k:v.cuda() for k, v in tokens.items()}
199
+ translate_tokens = self.model.generate(**tokens)
200
+ translate_batch = [
201
+ self.tokenizer.decode(t, skip_special_tokens=True)
202
+ for t in translate_tokens
203
+ ]
204
+ for (text, translated) in zip(text_batch, translate_batch):
205
+ translations[text] = translated
206
+
207
+ return [str(text.map(translations)) for text in text_sentences]
208
+
209
+
210
+ @st.cache_data()
211
+ def anonymize_analyzer(MarianText_letter, _analyzer, nom_propre):
212
+ MarianText_anonymize_letter = MarianText_letter
213
+ # st.write(MarianText_anonymize_letter)
214
+ analyzer_results_keep = []
215
+ analyzer_results_return = []
216
+ analyzer_results_saved = []
217
+ analyzer_results = _analyzer.analyze(text=MarianText_letter, language="en")
218
+ len_to_add = 0
219
+ analyser_results_to_sort = {}
220
+ i = 0
221
+ for element in analyzer_results:
222
+ analyser_results_to_sort[i] = element.start
223
+ i = i + 1
224
+ sorted_tuples = sorted(analyser_results_to_sort.items(), key=lambda x: x[1])
225
+ sorted_dict = {k: v for k, v in sorted_tuples}
226
+ # st.write(sorted_dict)
227
+
228
+ for element_raw in sorted_dict:
229
+ element = analyzer_results[element_raw]
230
+ word = MarianText_letter[element.start : element.end]
231
+ if word.lower().strip() in nom_propre:
232
+ word_to_replace = "**:green[" + word + "]** `[" + element.entity_type + "]`"
233
+ MarianText_anonymize_letter = (
234
+ MarianText_anonymize_letter[: element.start + len_to_add]
235
+ + word_to_replace
236
+ + MarianText_anonymize_letter[element.end + len_to_add :]
237
+ )
238
+ analyzer_results_saved.append(str(element) + ", word:" + word)
239
+ else:
240
+ word_to_replace = "**:red[" + word + "]** `[" + element.entity_type + "]`"
241
+ MarianText_anonymize_letter = (
242
+ MarianText_anonymize_letter[: element.start + len_to_add]
243
+ + word_to_replace
244
+ + MarianText_anonymize_letter[element.end + len_to_add :]
245
+ )
246
+ analyzer_results_keep.append(str(element) + ", word:" + word)
247
+ analyzer_results_return.append(element)
248
+ len_to_add = len_to_add + len(word_to_replace) - len(word)
249
+
250
+ return (
251
+ MarianText_anonymize_letter,
252
+ analyzer_results_return,
253
+ analyzer_results_keep,
254
+ analyzer_results_saved,
255
+ )
256
+
257
+
258
+ @st.cache_data()
259
+ def anonymize_engine(MarianText_letter, _analyzer_results_return, _engine):
260
+ result = _engine.anonymize(
261
+ text=MarianText_letter,
262
+ analyzer_results=_analyzer_results_return,
263
+ operators={
264
+ "PERSON": OperatorConfig("replace", {"new_value": ""}),
265
+ "LOCATION": OperatorConfig("replace", {"new_value": ""}),
266
+ },
267
+ )
268
+ return reformat_to_letter(result.text, nlp)
269
+
270
+
271
+ @st.cache_data()
272
+ def add_space_to_comma(texte):
273
+ text_list = []
274
+ regex = "(?<!\d)(\,)(?!\d)(?!.*\1)"
275
+ for sentence in nlp.process(texte).sentences:
276
+ text_space = re.sub(regex, " , ", sentence.text.replace("\n", " "))
277
+ text_space_no_db = text_space.replace(" ", " ")
278
+ text_list.append(text_space_no_db)
279
+ # print(text_space_no_db)
280
+ return " ".join(text_list)
281
+
282
+
283
+ @st.cache_data()
284
+ def add_space_to_endpoint(texte):
285
+ text_list = []
286
+ regex = "(?<!\d)(\.)(?!\d)(?!.*\1)"
287
+ for sentence in nlp.process(texte).sentences:
288
+ text_space = re.sub(regex, " . ", sentence.text.replace("\n", " "))
289
+ text_space_no_db = text_space.replace(" ", " ")
290
+ text_list.append(text_space_no_db)
291
+ # print(text_space_no_db)
292
+ return " ".join(text_list)
293
+
294
+
295
+ @st.cache_data()
296
+ def add_space_to_leftp(texte):
297
+ text_list = []
298
+ regex = "(?<!\d)(\()(?!\d)(?!.*\1)"
299
+ for sentence in nlp.process(texte).sentences:
300
+ text_space = re.sub(regex, " ( ", sentence.text.replace("\n", " "))
301
+ text_space_no_db = text_space.replace(" ", " ")
302
+ text_list.append(text_space_no_db)
303
+ # print(text_space_no_db)
304
+ return " ".join(text_list)
305
+
306
+
307
+ @st.cache_data()
308
+ def add_space_to_rightp(texte):
309
+ text_list = []
310
+ regex = "(?<!\d)(\))(?!\d)(?!.*\1)"
311
+ for sentence in nlp.process(texte).sentences:
312
+ text_space = re.sub(regex, " ) ", sentence.text.replace("\n", " "))
313
+ text_space_no_db = text_space.replace(" ", " ")
314
+ text_list.append(text_space_no_db)
315
+ # print(text_space_no_db)
316
+ return " ".join(text_list)
317
+
318
+
319
+ @st.cache_data()
320
+ def add_space_to_stroph(texte):
321
+ text_list = []
322
+ regex = "(?<!\d)(')(?!\d)(?!.*\1)"
323
+ for sentence in nlp.process(texte).sentences:
324
+ text_space = re.sub(regex, " ' ", sentence.text.replace("\n", " "))
325
+ text_space_no_db = text_space.replace(" ", " ")
326
+ text_list.append(text_space_no_db)
327
+ # print(text_space_no_db)
328
+ return " ".join(text_list)
329
+
330
+
331
+ @st.cache_data()
332
+ def add_space_to_comma_endpoint(texte):
333
+ text_fr_comma = add_space_to_comma(texte)
334
+ text_fr_comma_endpoint = add_space_to_endpoint(text_fr_comma)
335
+ text_fr_comma_endpoint_leftpc = add_space_to_leftp(text_fr_comma_endpoint)
336
+ text_fr_comma_endpoint_leftpc_right_pc = add_space_to_rightp(
337
+ text_fr_comma_endpoint_leftpc
338
+ )
339
+ # text_fr_comma_endpoint_leftpc_right_pc_stroph = add_space_to_stroph(
340
+ # text_fr_comma_endpoint_leftpc_right_pc
341
+ # )
342
+ return text_fr_comma_endpoint_leftpc_right_pc
343
+
344
+
345
+ @st.cache_data()
346
+ def get_translation_dict_correction():
347
+ dict_correction_FRspec = {
348
+ "PC": "head circumference",
349
+ "CP": "head circumference",
350
+ "palatine slot": "cleft palate",
351
+ "TSA": "autism",
352
+ "ASD": "autism",
353
+ "TDAH": "attention deficit hyperactivity disorder",
354
+ "ADHD": "attention deficit hyperactivity disorder",
355
+ "IME": " medical-educational institute for his intellectual disability",
356
+ "EMI": " medical-educational institute for his intellectual disability",
357
+ "CAMSP": "medical and social center for his mild global developmental delay",
358
+ "SESSAD": "specific education services for his mild global developmental delay",
359
+ "ESAT": "establishment and service of help by work for his mild global developmental delay",
360
+ "RDPM": "global developmental delay",
361
+ "IUGR": "intrauterin growth retardation",
362
+ "RCIU": "intrauterin growth retardation",
363
+ "CRIU": "intrauterin growth retardation",
364
+ "QI": "IQ ",
365
+ "QIT": "FSIQ ",
366
+ "ITQ": "FSIQ ",
367
+ "DS": "SD",
368
+ "FOP": "patent foramen ovale",
369
+ "PFO": "patent foramen ovale",
370
+ "ARCF": "fetal distress",
371
+ "\n": " ",
372
+ "associated": "with",
373
+ }
374
+
375
+ dict_correction = {}
376
+ for key, value in dict_correction_FRspec.items():
377
+ dict_correction[" " + key + " "] = " " + value + " "
378
+
379
+ with open("data/hp_fr_en_translated_marian_review_lwg.json", "r") as outfile:
380
+ hpo_translated = json.load(outfile)
381
+
382
+ for key, value in hpo_translated.items():
383
+ dict_correction[" " + key + " "] = " " + value + " "
384
+ return dict_correction
385
+
386
+
387
+ @st.cache_resource()
388
+ def change_name_patient(courrier, nom, prenom):
389
+ courrier_name = courrier
390
+ dict_correction_name = {
391
+ " " + prenom + " ": " CAS ",
392
+ " " + nom + " ": " INDEX ",
393
+ # " " + nom_maternel + " ": " INDEX ",
394
+ " M .": " M ",
395
+ " Dr .": " Docteur ",
396
+ " Dr ": " Docteur ",
397
+ " Pr .": " Professeur ",
398
+ " Pr ": " Professeur ",
399
+ }
400
+ for key, value in dict_correction_name.items():
401
+ courrier_name = courrier_name.replace(key, value)
402
+ return courrier_name
403
+
404
+
405
+ @st.cache_resource()
406
+ def translate_marian(courrier_name, _nlp, _marian_fr_en):
407
+ list_of_sentence = []
408
+ for sentence in _nlp.process(courrier_name).sentences:
409
+ list_of_sentence.append(sentence.text)
410
+ MarianText_raw = "\n".join(_marian_fr_en.translate(list_of_sentence))
411
+ return MarianText_raw
412
+
413
+
414
+ @st.cache_resource()
415
+ def correct_marian(MarianText_space, dict_correction):
416
+ MarianText = MarianText_space
417
+ list_replaced = []
418
+ for key, value in dict_correction.items():
419
+ if key in MarianText:
420
+ list_replaced.append(
421
+ 'Marian translation replaced "' + key + '" by "' + value
422
+ )
423
+ MarianText = MarianText.replace(key, value)
424
+ return MarianText, list_replaced
425
+
426
+
427
+ @st.cache_data()
428
+ def translate_letter(courrier, nom, prenom, _nlp, _marian_fr_en, dict_correction):
429
+ courrier_space = add_space_to_comma_endpoint(courrier)
430
+ courrier_name = change_name_patient(courrier_space, nom, prenom)
431
+ MarianText_raw = translate_marian(courrier_name, _nlp, _marian_fr_en)
432
+ MarianText_space = add_space_to_comma_endpoint(MarianText_raw)
433
+ MarianText, list_replaced = correct_marian(MarianText_space, dict_correction)
434
+ return MarianText, list_replaced
435
+
436
+
437
+ @st.cache_data()
438
+ def reformat_to_letter(text, _nlp):
439
+ cutsentence = []
440
+ for sentence in _nlp.process(text).sentences:
441
+ cutsentence.append(
442
+ sentence.text.replace(" ,", ",")
443
+ .replace(" .", ".")
444
+ .replace(" )", ")")
445
+ .replace(" (", "(")
446
+ .replace(" '", "'")
447
+ )
448
+ return " \n".join(cutsentence)
449
+
450
+
451
+ @st.cache_data()
452
+ def convert_df(df):
453
+ return df.to_csv(sep="\t").encode("utf-8")
454
+
455
+
456
+ @st.cache_data()
457
+ def add_biometrics(text, _nlp):
458
+ cutsentence_with_biometrics = []
459
+ cutsentence = []
460
+ for sentence in _nlp.process(text).sentences:
461
+ cutsentence.append(sentence.text)
462
+ keep_element = ["cm", "kg", "qit", "qi"]
463
+ for sentence in cutsentence:
464
+ if any(ext in sentence.lower() for ext in keep_element):
465
+ additional_terms = []
466
+ if "SD" in sentence or "DS" in sentence:
467
+ sentence = sentence.replace("DS", "SD")
468
+ try:
469
+ kg_sd = re.findall("kg(.*?)sd", sentence.lower())[0]
470
+ num_kg_sd = re.findall("([\-0-9.])", kg_sd)[0]
471
+ # print(kg_sd)
472
+ kg_sd = float(num_kg_sd)
473
+ print(kg_sd)
474
+ if kg_sd >= 2:
475
+ additional_terms.append("Increased body weight")
476
+ if kg_sd <= -2:
477
+ additional_terms.append("Decreased body weight")
478
+ except:
479
+ print("Incorrect weight recognition pattern")
480
+ print(sentence)
481
+ try:
482
+ if "is" in sentence.lower():
483
+ height_sd_alpha = re.findall("\ is(.*?)d", sentence.lower())[0]
484
+ if "cm" not in height_sd_alpha:
485
+ height_sd_raw = height_sd_alpha
486
+ if "easure" in sentence.lower():
487
+ height_sd_raw = re.findall("easure(.*?)d", sentence.lower())[0]
488
+ print(height_sd_raw)
489
+ height_sd = re.findall("m(.*?)s", height_sd_raw)[0]
490
+ print(height_sd)
491
+ num_height_sd = re.findall("([\-0-9.])", height_sd)[0]
492
+ height_sd = float(num_height_sd)
493
+ print(height_sd)
494
+ if height_sd >= 2:
495
+ additional_terms.append("Tall stature")
496
+ if height_sd <= -2:
497
+ additional_terms.append("Short stature")
498
+ except:
499
+ print("Incorrect height recognition pattern")
500
+ print(sentence)
501
+ try:
502
+ pc_sd_raw = (
503
+ re.findall("head(.*?)d", sentence.lower())[0]
504
+ .replace("(", "")
505
+ .replace(")", "")
506
+ .replace(" ", "")
507
+ )
508
+ pc_sd = re.findall("cm(.*?)s", pc_sd_raw)[0]
509
+ num_pc_sd = re.findall("([\-0-9.])", pc_sd)[0]
510
+ pc_sd = float(num_pc_sd)
511
+ print(pc_sd)
512
+ if pc_sd >= 2:
513
+ additional_terms.append("Macrocephaly")
514
+ elif pc_sd <= -2:
515
+ additional_terms.append("Microcephaly")
516
+ except:
517
+ print("Incorrect head circumference recognition pattern")
518
+ print(sentence)
519
+ print(additional_terms)
520
+ if "FSIQ" in sentence or "IQ" in sentence:
521
+ try:
522
+ iq_score = re.findall("iq.*?(\d.*?)\D", sentence.lower())[0]
523
+ iq_score = float(iq_score)
524
+ print(iq_score)
525
+ if iq_score >= 70 and iq_score < 84:
526
+ additional_terms.append("Intellectual disability, borderline")
527
+ elif iq_score >= 50 and iq_score < 69:
528
+ additional_terms.append("Intellectual disability, mild")
529
+ elif iq_score >= 35 and iq_score < 49:
530
+ additional_terms.append("Intellectual disability, moderate")
531
+ elif iq_score >= 20 and iq_score < 34:
532
+ additional_terms.append("Intellectual disability, severe")
533
+ elif iq_score < 20:
534
+ additional_terms.append("Intellectual disability, profound")
535
+ print(additional_terms)
536
+ except:
537
+ print("Incorrect IQ recognition pattern")
538
+ print(sentence)
539
+ cutsentence_with_biometrics.append(
540
+ sentence + " This means " + ", ".join(additional_terms) + "."
541
+ )
542
+ else:
543
+ cutsentence_with_biometrics.append(sentence)
544
+ print(cutsentence_with_biometrics)
545
+ cutsentence_with_biometrics_return = [
546
+ i for i in cutsentence_with_biometrics if i != "."
547
+ ]
548
+ return " ".join(cutsentence_with_biometrics_return), additional_terms
549
+
550
+
551
+ models_status = get_models()
552
+ nlp, marian_fr_en = get_nlp_marian()
553
+ dict_correction = get_translation_dict_correction()
554
+ nom_propre = get_list_not_deidentify()
555
+ analyzer, engine = config_deidentify()
556
+
557
+ if "load_state" not in st.session_state:
558
+ st.session_state.load_state = False
559
+
560
+ with st.form("my_form"):
561
+ c1, c2 = st.columns(2)
562
+ with c1:
563
+ nom = st.text_input("Nom du patient ", "Doe", key="name")
564
+ with c2:
565
+ prenom = st.text_input("Prénom du patient", "John", key="surname")
566
+ courrier = st.text_area(
567
+ "Courrier à coller", "Chers collegues, ...", height=200, key="letter"
568
+ )
569
+
570
+ submit_button = st.form_submit_button(
571
+ label="Submit",
572
+ )
573
+
574
+
575
+ if submit_button or st.session_state.load_state:
576
+ st.session_state.load_state = True
577
+ MarianText, list_replaced = translate_letter(
578
+ courrier, nom, prenom, nlp, marian_fr_en, dict_correction
579
+ )
580
+ MarianText_letter = reformat_to_letter(MarianText, nlp)
581
+
582
+ st.subheader("Translation and De-identification")
583
+ (
584
+ MarianText_anonymize_letter_analyze,
585
+ analyzer_results_return,
586
+ analyzer_results_keep,
587
+ analyzer_results_saved,
588
+ ) = anonymize_analyzer(MarianText_letter, analyzer, nom_propre)
589
+ with st.expander("See country-specific correction"):
590
+ st.write(list_replaced)
591
+ with st.expander("See de-identified element"):
592
+ st.write("De-identified elements")
593
+ st.write(analyzer_results_keep)
594
+ st.write("Keep elements")
595
+ st.write(analyzer_results_saved)
596
+
597
+ st.caption(MarianText_anonymize_letter_analyze)
598
+
599
+ MarianText_anonymize_letter_engine = anonymize_engine(
600
+ MarianText_letter, analyzer_results_return, engine
601
+ )
602
+
603
+ MarianText_anonymize_letter_engine_modif = pd.DataFrame(
604
+ [x for x in MarianText_anonymize_letter_engine.split("\n")]
605
+ )
606
+ MarianText_anonymize_letter_engine_modif.columns = [
607
+ "Modify / curate the automatically translated and de-identified letter before downloading:"
608
+ ]
609
+ MarianText_anonymize_letter_engine_df = st.experimental_data_editor(
610
+ MarianText_anonymize_letter_engine_modif,
611
+ num_rows="dynamic",
612
+ key="letter_editor",
613
+ use_container_width=True,
614
+ )
615
+
616
+ st.caption("Modify cells above 👆 or even ➕ add rows, before downloading 👇")
617
+
618
+ st.download_button(
619
+ "Download translated and de-identified letter",
620
+ convert_df(MarianText_anonymize_letter_engine_df),
621
+ "translated_and_deindentified_letter.txt",
622
+ "text",
623
+ key="download-translation",
624
+ )
625
+
626
+ st.subheader("Summarization")
627
+
628
+ MarianText_anonymized_reformat_space = add_space_to_comma_endpoint(
629
+ MarianText_anonymize_letter_engine
630
+ )
631
+ MarianText_anonymized_reformat_biometrics, additional_terms = add_biometrics(
632
+ MarianText_anonymized_reformat_space, nlp
633
+ )
634
+
635
+ with st.expander("See additional terms extracted with biometrics analysis"):
636
+ st.write(additional_terms)
637
+
638
+ with open("sample_translated_deindentified_biometrics.txt", "w") as f:
639
+ f.write(MarianText_anonymized_reformat_biometrics)
640
+
641
+ with open("extract_clinphen_patient.tsv", "w") as outfile:
642
+ subprocess.run(
643
+ [
644
+ "clinphen",
645
+ "sample_translated_deindentified_biometrics.txt",
646
+ ],
647
+ stdout=outfile,
648
+ )
649
+
650
+ clinphen = pd.read_csv("extract_clinphen_patient.tsv", sep="\t")
651
+
652
+ clinphen_df = st.experimental_data_editor(
653
+ clinphen, num_rows="dynamic", key="data_editor"
654
+ )
655
+
656
+ st.caption("Modify cells above 👆 or even ➕ add rows, before downloading 👇")
657
+
658
+ st.download_button(
659
+ "Download summarized letter in HPO format",
660
+ convert_df(clinphen_df),
661
+ "translated_and_deindentified_letter.tsv",
662
+ "text/csv",
663
+ key="download-summarization",
664
+ )
pyproject.toml ADDED
@@ -0,0 +1,19 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ [tool.poetry]
2
+ name = "linguo_franca"
3
+ version = "0.1.0"
4
+ description = ""
5
+ authors = ["kyauy <kevin.yauy@gmail.com>"]
6
+
7
+ [tool.poetry.dependencies]
8
+ python = ">=3.8.0,<3.12"
9
+ pyhpo = "^3.1.3"
10
+ clinphen = "^1.28"
11
+ argostranslate = "^1.8.0"
12
+ transformers = "^4.26.1"
13
+
14
+ [tool.poetry.dev-dependencies]
15
+ pytest = "^5.2"
16
+
17
+ [build-system]
18
+ requires = ["poetry-core>=1.0.0"]
19
+ build-backend = "poetry.core.masonry.api"