import json import os import sqlite3 import shutil import time import tempfile import numpy as np import soundfile as sf from pathlib import Path from itertools import permutations from typing import Any, Dict, List, Optional from reasoning_pipeline import aggregate_reasoning_summaries MODEL_PATH = "best_audio_separation_model.pt" _model = None def get_model(): global _model if _model is None: from model import load_model _model = load_model(MODEL_PATH) return _model def apply_wiener_filter(est_sources, mixture, iterations=1): """ A simplified Wiener filter refinement. In source separation, this often refers to re-masking the mixture based on the relative energy of the estimated sources. """ # eps to avoid division by zero eps = 1e-10 # Square the estimates to get power/variance proxies est_power = np.maximum(np.abs(est_sources)**2, eps) total_power = np.sum(est_power, axis=0, keepdims=True) + eps # The Wiener gain is est_power / total_power # We apply this gain to the original mixture refined_sources = (est_power / total_power) * mixture return refined_sources def save_waveform_plot(waveform, sample_rate, title, path=None): import matplotlib.pyplot as plt import torch if waveform.ndim > 1: waveform = waveform.mean(dim=0) data = waveform.cpu().numpy() times = np.arange(data.shape[-1]) / sample_rate fig, ax = plt.subplots(figsize=(10, 2.5)) ax.plot(times, data, linewidth=0.7) ax.set_title(title) ax.set_xlabel("Time (s)") ax.set_ylabel("Amplitude") ax.set_xlim(0, times[-1] if len(times) > 0 else 1) ax.grid(True) fig.tight_layout() if path is None: temp_image = tempfile.NamedTemporaryFile(suffix=".png", delete=False) fig.savefig(temp_image.name) plt.close(fig) return temp_image.name out_path = str(path) fig.savefig(out_path) plt.close(fig) return out_path def predict_sources(waveform, sr, reference_waveforms=None): import torch import torchaudio if waveform.shape[0] > 1: waveform = waveform.mean(dim=0, keepdim=True) if sr != 16000: waveform = torchaudio.functional.resample( waveform, sr, 16000, ) waveform = waveform.squeeze(0) with torch.no_grad(): mixture = waveform.unsqueeze(0) prediction = get_model()(mixture) prediction = prediction.squeeze(0).permute(1, 0) # Convert to numpy for post-processing as per your evaluation snippet pred_np = prediction.cpu().numpy() # [3, T] mix_np = waveform.cpu().numpy() # [T] # 1. Apply Wiener Filter refined_preds = apply_wiener_filter(pred_np, mix_np) # 2. Automated Permutation Alignment using Reference Audios if reference_waveforms is not None and len(reference_waveforms) > 0: best_perm = None min_mse = float('inf') num_sources = refined_preds.shape[0] for perm in permutations(range(num_sources)): current_mse = 0 for i, p in enumerate(perm): if i < len(reference_waveforms) and reference_waveforms[i] is not None: # Compare the first N samples to find the best match ref = reference_waveforms[i] length = min(refined_preds[p].shape[0], ref.shape[0]) current_mse += np.mean((ref[:length] - refined_preds[p][:length]) ** 2) if current_mse < min_mse: min_mse = current_mse best_perm = perm refined_preds = np.array([refined_preds[p] for p in best_perm]) return torch.from_numpy(refined_preds.copy()), 16000 def save_separated_sources(prediction, output_dir, base_name, patient_names=None): import torch output_dir = Path(output_dir) output_dir.mkdir(parents=True, exist_ok=True) patient_names = patient_names or ["Patient 1", "Patient 2", "Patient 3"] patient_names = [name if name else f"Patient {idx + 1}" for idx, name in enumerate(patient_names)] output_audio_paths = [] output_image_paths = [] for i in range(prediction.shape[0]): audio_name = f"{base_name}_s{i+1}.wav" audio_path = output_dir / audio_name save_audio_file( str(audio_path), prediction[i].unsqueeze(0), 16000, ) output_audio_paths.append(str(audio_path)) image_name = f"{base_name}_s{i+1}_waveform.png" image_path = output_dir / image_name save_waveform_plot( prediction[i], 16000, title=f"Separated waveform - {patient_names[i]}", path=image_path, ) output_image_paths.append(str(image_path)) return output_audio_paths, output_image_paths def separate_audio_file(audio_path, output_dir, patient_names=None): waveform, sr = load_audio(audio_path) prediction, sample_rate = predict_sources(waveform, sr) return save_separated_sources(prediction, output_dir, Path(audio_path).stem, patient_names) def load_audio(audio_path): import torch try: import torchaudio return torchaudio.load(audio_path) except (ImportError, RuntimeError, OSError): try: data, sr = sf.read(audio_path, dtype="float32") if data.ndim == 1: waveform = torch.from_numpy(data).unsqueeze(0) else: waveform = torch.from_numpy(data.T) return waveform, sr except (RuntimeError, ValueError, OSError): import librosa data, sr = librosa.load(audio_path, sr=None, mono=False) if data.ndim == 1: waveform = torch.from_numpy(data).unsqueeze(0) else: waveform = torch.from_numpy(data) return waveform, sr def save_audio_file(path, waveform, sample_rate): import torch audio = waveform.detach().cpu().numpy() if audio.ndim == 1: audio = audio[np.newaxis, :] if audio.shape[0] > 1: audio = audio.T else: audio = audio[0] sf.write(path, audio, sample_rate) # save_audio_file now only saves the audio RESULTS_DIR = Path("pipeline_results") REASONING_SUMMARY_PATH = RESULTS_DIR / "reasoning_summary.json" PATIENT_REGISTRY_PATH = RESULTS_DIR / "patient_registry.json" HISTORY_RECORDS_PATH = RESULTS_DIR / "history_records.json" DB_PATH = RESULTS_DIR / "speformer.db" AUDIO_STORAGE_DIR = RESULTS_DIR / "audio" GNN_RUN_ROOT = RESULTS_DIR / "gnn_runs" DEFAULT_GNN_CHECKPOINT = "best_audio_separation_model.pt" def _get_db_connection(): RESULTS_DIR.mkdir(parents=True, exist_ok=True) conn = sqlite3.connect(DB_PATH) conn.row_factory = sqlite3.Row conn.execute("PRAGMA journal_mode=WAL;") return conn def initialize_database(): conn = _get_db_connection() conn.execute( """ CREATE TABLE IF NOT EXISTS patient_registry ( id INTEGER PRIMARY KEY, patient_id TEXT UNIQUE, name TEXT, reference_audio TEXT, local_reference_audio TEXT, created_at TEXT ) """ ) conn.execute( """ CREATE TABLE IF NOT EXISTS history_records ( id INTEGER PRIMARY KEY, timestamp TEXT, mix_audio TEXT, local_mix_audio TEXT, patient_names TEXT, separated_sources TEXT, run_dirs TEXT, reasoning_summary_path TEXT, reasoning_count INTEGER ) """ ) conn.execute( """ CREATE TABLE IF NOT EXISTS audio_files ( id INTEGER PRIMARY KEY, path TEXT UNIQUE, file_type TEXT, patient_id TEXT, created_at TEXT, notes TEXT ) """ ) conn.commit() conn.close() def _record_audio_file_metadata(path: str, file_type: str, patient_id: Optional[str] = None, notes: Optional[str] = None): conn = None try: initialize_database() conn = _get_db_connection() conn.execute( "INSERT OR IGNORE INTO audio_files (path, file_type, patient_id, created_at, notes) VALUES (?, ?, ?, ?, ?)", (str(Path(path).resolve()), file_type, patient_id, time.strftime("%Y-%m-%dT%H:%M:%SZ", time.gmtime()), notes), ) conn.commit() except Exception: pass finally: if conn: conn.close() def _copy_audio_to_storage(src_path: Optional[str], subdir: str, prefix: str) -> Optional[str]: if not src_path: return None src = Path(src_path) try: if not src.exists(): return None src_resolved = src.resolve() if RESULTS_DIR in src_resolved.parents or src_resolved == RESULTS_DIR.resolve(): return str(src_resolved) except Exception: pass storage_dir = AUDIO_STORAGE_DIR / subdir storage_dir.mkdir(parents=True, exist_ok=True) timestamp = time.strftime("%Y%m%d%H%M%S", time.gmtime()) dest = storage_dir / f"{prefix}_{timestamp}_{src.name}" shutil.copy2(src, dest) _record_audio_file_metadata(str(dest), subdir, prefix) return str(dest) def save_patient_registry(patient_entries: List[Dict[str, str]], registry_path: Optional[Path] = None) -> Path: path = Path(registry_path) if registry_path is not None else PATIENT_REGISTRY_PATH path.parent.mkdir(parents=True, exist_ok=True) initialize_database() conn = _get_db_connection() local_entries = [] for entry in patient_entries: patient_id = entry.get("patient_id") or entry.get("id") or "" name = entry.get("name") or "" ref_audio = entry.get("reference_audio") local_ref_audio = _copy_audio_to_storage(ref_audio, "patient_reference", patient_id) if ref_audio else None conn.execute( "INSERT OR REPLACE INTO patient_registry (patient_id, name, reference_audio, local_reference_audio, created_at) VALUES (?, ?, ?, ?, ?)", ( patient_id, name, str(ref_audio) if ref_audio else None, local_ref_audio, time.strftime("%Y-%m-%dT%H:%M:%SZ", time.gmtime()), ), ) local_entries.append({ "patient_id": patient_id, "name": name, "reference_audio": local_ref_audio or (str(ref_audio) if ref_audio else None), }) conn.commit() conn.close() with open(path, "w", encoding="utf-8") as f: json.dump(local_entries, f, indent=2) return path def load_patient_registry(registry_path: Optional[Path] = None) -> List[Dict[str, str]]: if registry_path is None and DB_PATH.exists(): try: initialize_database() conn = _get_db_connection() cursor = conn.execute("SELECT patient_id, name, local_reference_audio AS reference_audio FROM patient_registry ORDER BY id") rows = cursor.fetchall() conn.close() if rows: return [{"patient_id": row["patient_id"], "name": row["name"], "reference_audio": row["reference_audio"]} for row in rows] except Exception: pass path = Path(registry_path) if registry_path is not None else PATIENT_REGISTRY_PATH if not path.exists(): return [] try: with open(path, "r", encoding="utf-8") as f: data = json.load(f) if isinstance(data, list): return data except Exception: pass return [] def resolve_patient_names(patient_names=None, registry_path: Optional[Path] = None): registry = load_patient_registry(registry_path) resolved = [] patient_names = patient_names or [] for idx in range(3): name = None if idx < len(patient_names) and patient_names[idx]: name = patient_names[idx] elif idx < len(registry) and registry[idx].get("name"): name = registry[idx]["name"] if not name: name = f"Patient {idx + 1}" resolved.append(name) return resolved def load_reasoning_summary(results_path: Optional[Path] = None): path = Path(results_path) if results_path is not None else REASONING_SUMMARY_PATH if not path.exists(): return [] try: with open(path, "r", encoding="utf-8") as f: return json.load(f) except Exception: return [] def load_history_records(history_path: Optional[Path] = None) -> List[Dict[str, str]]: if DB_PATH.exists(): try: initialize_database() conn = _get_db_connection() cursor = conn.execute("SELECT * FROM history_records ORDER BY id") rows = cursor.fetchall() conn.close() history = [] for row in rows: local_mix_audio = row["local_mix_audio"] or row["mix_audio"] history.append({ "timestamp": row["timestamp"], "mix_audio": local_mix_audio, "patient_names": json.loads(row["patient_names"] or "[]"), "separated_sources": json.loads(row["separated_sources"] or "[]"), "run_dirs": json.loads(row["run_dirs"] or "[]"), "reasoning_summary_path": row["reasoning_summary_path"], "reasoning_count": row["reasoning_count"], "local_mix_audio": row["local_mix_audio"], }) return history except Exception: pass path = Path(history_path) if history_path is not None else HISTORY_RECORDS_PATH if not path.exists(): return [] try: with open(path, "r", encoding="utf-8") as f: data = json.load(f) if isinstance(data, list): return data except Exception: pass return [] def append_history_record(record: Dict[str, object], history_path: Optional[Path] = None) -> Path: path = Path(history_path) if history_path is not None else HISTORY_RECORDS_PATH local_mix_audio = _copy_audio_to_storage(record.get("mix_audio"), "mix_audio", "mix_audio") if record.get("mix_audio") else None if local_mix_audio: record["mix_audio"] = local_mix_audio initialize_database() conn = _get_db_connection() conn.execute( "INSERT INTO history_records (timestamp, mix_audio, local_mix_audio, patient_names, separated_sources, run_dirs, reasoning_summary_path, reasoning_count) VALUES (?, ?, ?, ?, ?, ?, ?, ?)", ( record.get("timestamp"), str(record.get("mix_audio")) if record.get("mix_audio") else None, local_mix_audio, json.dumps(record.get("patient_names") or []), json.dumps(record.get("separated_sources") or []), json.dumps(record.get("run_dirs") or []), str(record.get("reasoning_summary_path")) if record.get("reasoning_summary_path") else None, int(record.get("reasoning_count") or 0), ), ) conn.commit() conn.close() history = load_history_records(path) history.append(record) path.parent.mkdir(parents=True, exist_ok=True) with open(path, "w", encoding="utf-8") as f: json.dump(history, f, indent=2) return path def load_wav2vec(device): import torch import importlib try: transformers = importlib.import_module("transformers") except ModuleNotFoundError as exc: raise ModuleNotFoundError( "Required package 'transformers' is not installed. Please install it with `pip install transformers` and restart the app." ) from exc Wav2Vec2Model = getattr(transformers, "Wav2Vec2Model") Wav2Vec2Processor = getattr(transformers, "Wav2Vec2Processor") processor = Wav2Vec2Processor.from_pretrained("facebook/wav2vec2-base-960h") model = Wav2Vec2Model.from_pretrained("facebook/wav2vec2-base-960h") model = model.to(device) model.eval() return processor, model _live_sr = 16000 LIVE_PROCESSING_WINDOW_SECONDS = 5.0 LIVE_OVERLAP_SECONDS = 1.0 _live_processor = None _live_wav2vec_model = None _live_gnn_model = None _live_device = None def _initialize_models_for_live_processing(): import torch global _live_processor, _live_wav2vec_model, _live_gnn_model, _live_device if _live_device is None: _live_device = torch.device("cuda" if torch.cuda.is_available() else "cpu") if _live_processor is None or _live_wav2vec_model is None: _live_processor, _live_wav2vec_model = load_wav2vec(_live_device) if _live_gnn_model is None: from gnn import load_gnn_model _live_gnn_model = load_gnn_model(DEFAULT_GNN_CHECKPOINT, _live_device) return _live_processor, _live_wav2vec_model, _live_gnn_model, _live_device def process_audio_chunk_for_separation(audio_chunk_tensor): """Expects a 1D tensor at 16kHz.""" import torch prediction, _ = predict_sources(audio_chunk_tensor.unsqueeze(0), 16000) return prediction def infer_on_separated_chunk( separated_chunk_np, gnn_model, processor, wav2vec_model, device, patient_manager, patient_id, timestamp, ): """Runs behavior inference and clinical state tracking on a single audio chunk.""" import torch inputs = processor(separated_chunk_np, sampling_rate=16000, return_tensors="pt", padding=True) input_values = inputs.input_values.to(device) with torch.no_grad(): out = wav2vec_model(input_values) emb = out.last_hidden_state.mean(dim=1) from gnn import build_chain_edge_index from torch_geometric.data import Data edge_index = build_chain_edge_index(1).to(device) data = Data(x=emb, edge_index=edge_index) w_logits, c_logits = gnn_model(data) w_prob = float(torch.sigmoid(w_logits).view(-1)[0].item()) c_prob = float(torch.sigmoid(c_logits).view(-1)[0].item()) from gnn import estimate_breathing_rate_bpm br_bpm = estimate_breathing_rate_bpm(separated_chunk_np, 16000, len(separated_chunk_np)/16000) return patient_manager.update_and_get_clinical_state(patient_id, w_prob, c_prob, breathing_rate=br_bpm, timestamp=timestamp) def run_end_to_end( mix_audio_path, patient_names=None, reference_audio_paths=None, # New argument to accept reference audio paths gnn_checkpoint: Optional[str] = None, device_str: Optional[str] = None, ): import torch if not mix_audio_path: raise ValueError("No mixture audio file provided.") # Note: reference_audio_paths are passed but not used by the current separate_audio/predict_sources patient_names = resolve_patient_names(patient_names) outputs = separate_audio( mix_audio_path, patient_names=patient_names, reference_audio_paths=reference_audio_paths, # Pass reference audio paths ) separated_audio_paths = outputs[:3] device_str = device_str or ("cuda" if torch.cuda.is_available() else "cpu") device = torch.device(device_str) processor, wav2vec_model = load_wav2vec(device) from gnn import load_gnn_model gnn_model = load_gnn_model(gnn_checkpoint or DEFAULT_GNN_CHECKPOINT, device) GNN_RUN_ROOT.mkdir(parents=True, exist_ok=True) behavior_results = [] for audio_path in separated_audio_paths: from full_pipeline import infer_on_audio_file result = infer_on_audio_file( Path(audio_path), gnn_model, processor, wav2vec_model, GNN_RUN_ROOT, device, ) if result is not None: behavior_results.append(result) run_dirs = [Path(item["artifacts"]["run_dir"]) for item in behavior_results if item.get("artifacts")] # Construct metadata mapping the audio_id (filename stem) to the selected patient name for human-readable reporting patient_meta = {} for i, audio_path in enumerate(separated_audio_paths): if audio_path: stem = Path(audio_path).stem if i < len(patient_names): patient_meta[stem] = {"name": patient_names[i]} reasoning_summaries = aggregate_reasoning_summaries(run_dirs, RESULTS_DIR, patient_meta=patient_meta) history_record = { "timestamp": time.strftime("%Y-%m-%dT%H:%M:%SZ", time.gmtime()), "mix_audio": str(mix_audio_path), "patient_names": patient_names, "separated_sources": separated_audio_paths, "run_dirs": [str(path) for path in run_dirs], "reasoning_summary_path": str(REASONING_SUMMARY_PATH), "reasoning_count": len(reasoning_summaries), } append_history_record(history_record) return outputs, reasoning_summaries, history_record def monitoring_table_rows(results_path: Optional[Path] = None): records = load_reasoning_summary(results_path) rows = [] for item in records: rows.append([ item.get("audio_id"), item.get("overall_state"), item.get("mean_wheeze_prob"), item.get("mean_crackle_prob"), item.get("breathing_rate_mean"), item.get("comment"), ]) return rows def search_history_records(query: str, history_path: Optional[Any] = None): if not query: return [] query_lower = query.strip().lower() records = load_history_records(history_path) results = [] for item in records: patient_names = item.get("patient_names") or [] mix_audio = str(item.get("mix_audio", "")) timestamp = str(item.get("timestamp", "")) if ( query_lower in mix_audio.lower() or query_lower in timestamp.lower() or any(query_lower in str(name).lower() for name in patient_names) ): results.append([ item.get("timestamp"), mix_audio, ", ".join([str(name) for name in patient_names if name]), item.get("reasoning_count"), ]) return results def search_reasoning_records(query: str, results_path: Optional[Any] = None): if not query: return [] query_lower = query.strip().lower() records = load_reasoning_summary(results_path) results = [] for item in records: audio_id = str(item.get("audio_id", "")) if query_lower in audio_id.lower(): results.append([ item.get("audio_id"), item.get("overall_state"), item.get("mean_wheeze_prob"), item.get("mean_crackle_prob"), item.get("breathing_rate_mean"), item.get("comment"), ]) return results def separate_audio(audio_path, patient_names=None, reference_audio_paths=None): # New argument import torch import torchaudio waveform, sr = load_audio(audio_path) # Load reference waveforms if provided for alignment ref_waveforms = [] if reference_audio_paths: for path in reference_audio_paths: if path and Path(path).exists(): ref_wav, _ = load_audio(path) ref_waveforms.append(ref_wav.mean(dim=0).cpu().numpy()) else: ref_waveforms.append(None) if waveform.shape[0] > 1: waveform = waveform.mean(dim=0, keepdim=True) if sr != 16000: waveform = torchaudio.functional.resample( waveform, sr, 16000, ) waveform = waveform.squeeze(0) with torch.no_grad(): # Now passing the references to predict_sources for alignment logic prediction, _ = predict_sources(waveform.unsqueeze(0), 16000, reference_waveforms=ref_waveforms) patient_names = resolve_patient_names(patient_names) output_dir = AUDIO_STORAGE_DIR / "separated" / Path(audio_path).stem output_audio_paths, output_image_paths = save_separated_sources( prediction, output_dir, Path(audio_path).stem, patient_names=patient_names, ) while len(output_audio_paths) < 3: output_audio_paths.append(None) while len(output_image_paths) < 3: output_image_paths.append(None) return output_audio_paths + output_image_paths