---
title: Splice Site
emoji: 🧬
colorFrom: green
colorTo: purple
sdk: gradio
sdk_version: 6.14.0
python_version: "3.13"
app_file: app.py
pinned: false
license: agpl-3.0
suggested_hardware: t4-small
models:
  - multimolecule/openspliceai-mane-400nt
  - multimolecule/pangolin
  - multimolecule/sptransformer
  - multimolecule/maxentscan-score5
  - multimolecule/maxentscan-score3
tags:
  - biology
  - dna
  - splicing
  - splice-site
  - multimolecule
---

Interactive splice-site scoring with MultiMolecule.

Enter one DNA sequence or upload a single-record FASTA file, choose a splice-site checkpoint, and inspect ranked splice-site calls, per-position scores, run metadata, and a Matplotlib score track. Results can be downloaded as per-position CSV or normalized JSON with `splice_sites`, `scores`, `channels`, and `sequence` keys.

The OpenSpliceAI, Pangolin, and SpTransformer options run full-sequence `splice-site` pipelines. The MaxEntScan option uses the same pipeline interface over sliding donor (`score5`) and acceptor (`score3`) motif windows because MaxEntScan is a fixed-window splice-signal scorer rather than a full-length neural sequence model.