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Update app.py
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app.py
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import
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import joblib
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import numpy as np
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from propy import AAComposition
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from sklearn.preprocessing import MinMaxScaler
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#
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model = joblib.load("SVM.joblib")
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scaler = MinMaxScaler()
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aac = np.array(list(AAComposition.CalculateAADipeptideComposition(sequence)), dtype=float)
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# Normalize using the pre-trained scaler (Ensure the scaler is loaded correctly)
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normalized_features = scaler.fit_transform([aac]) # Don't use fit_transform(), only transform()
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return normalized_features
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prediction = model.predict(features)[0]
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# Create Gradio interface
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iface = gr.Interface(
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fn=predict,
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inputs=gr.Textbox(label="Enter Protein Sequence"),
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outputs=gr.Label(label="Prediction"),
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title="AMP Classifier",
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description="Enter an amino acid sequence to predict whether it's an antimicrobial peptide (AMP) or not."
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)
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#
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iface.launch(share=True)
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from fastapi import FastAPI, HTTPException
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from pydantic import BaseModel
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import joblib
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import numpy as np
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from propy import AAComposition
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from sklearn.preprocessing import MinMaxScaler
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# Initialize FastAPI app
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app = FastAPI()
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# Load trained SVM model and scaler
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model = joblib.load("SVM.joblib")
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scaler = MinMaxScaler()
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# Define request schema
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class SequenceInput(BaseModel):
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sequence: str
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def extract_features(sequence: str):
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"""Extract Amino Acid Composition (AAC) features and normalize them."""
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try:
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aac = np.array(list(AAComposition.CalculateAADipeptideComposition(sequence)), dtype=float)
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normalized_features = scaler.fit_transform([aac]) # Don't use fit_transform(), only transform()
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return normalized_features
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except Exception as e:
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raise HTTPException(status_code=400, detail=f"Feature extraction failed: {str(e)}")
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@app.post("/predict/")
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def predict(input_data: SequenceInput):
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"""Predict AMP vs Non-AMP from protein sequence."""
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features = extract_features(input_data.sequence)
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prediction = model.predict(features)[0]
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result = "AMP" if prediction == 1 else "Non-AMP"
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return {"prediction": result}
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# Run using: uvicorn script_name:app --host 0.0.0.0 --port 8000 --reload
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