bio-experiment / run_agent.py
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"""Run the bio-experiment environment with Qwen3.5-0.8B as the planning agent."""
from __future__ import annotations
import json
import os
import re
import time
from pathlib import Path
from typing import Any, Dict, List, Optional
import torch
from transformers import AutoModelForCausalLM, AutoTokenizer, pipeline
from models import (
ActionType,
ExperimentAction,
ExperimentObservation,
OutputType,
build_agent_observation_context,
build_agent_system_prompt,
)
from server.hackathon_environment import BioExperimentEnvironment
DASHBOARD_STATE_PATH = Path(__file__).parent / "_dashboard_state.json"
DASHBOARD_CMD_PATH = Path(__file__).parent / "_dashboard_cmd.json"
USE_PIPELINE = os.getenv("RUN_AGENT_USE_PIPELINE", "0").strip().lower() not in {"0", "false", "off"}
def _parse_thinking_flag() -> bool:
import sys
if "--no-thinking" in sys.argv:
return False
if "--thinking" in sys.argv:
return True
return os.getenv("RUN_AGENT_ENABLE_THINKING", "1").strip().lower() not in {"0", "false", "off"}
ENABLE_THINKING = _parse_thinking_flag()
MODEL_ID = "Qwen/Qwen3.5-2B"
MAX_EPISODE_STEPS = int(os.getenv("RUN_AGENT_MAX_EPISODE_STEPS", "20"))
PIPELINE_TASK = "text-generation"
ACTION_TYPES = [a.value for a in ActionType]
ACTION_TYPE_ALIASES = {
"collect_samples": ActionType.COLLECT_SAMPLE.value,
"collect_sample_from_bone_marrow": ActionType.COLLECT_SAMPLE.value,
"collect_samples_from_bone_marrow": ActionType.COLLECT_SAMPLE.value,
"prepare_sc_library": ActionType.PREPARE_LIBRARY.value,
"sequence_single_cells": ActionType.SEQUENCE_CELLS.value,
"qc": ActionType.RUN_QC.value,
"run_quality_control": ActionType.RUN_QC.value,
"cluster": ActionType.CLUSTER_CELLS.value,
"de_analysis": ActionType.DIFFERENTIAL_EXPRESSION.value,
"differential_expression_analysis": ActionType.DIFFERENTIAL_EXPRESSION.value,
"trajectory_inference": ActionType.TRAJECTORY_ANALYSIS.value,
"infer_trajectory": ActionType.TRAJECTORY_ANALYSIS.value,
"network_inference": ActionType.REGULATORY_NETWORK_INFERENCE.value,
"select_markers": ActionType.MARKER_SELECTION.value,
"final_conclusion": ActionType.SYNTHESIZE_CONCLUSION.value,
}
SYSTEM_PROMPT = build_agent_system_prompt()
STANDARD_PIPELINE_ORDER = [
ActionType.COLLECT_SAMPLE,
ActionType.SELECT_COHORT,
ActionType.PREPARE_LIBRARY,
ActionType.SEQUENCE_CELLS,
ActionType.RUN_QC,
ActionType.FILTER_DATA,
ActionType.NORMALIZE_DATA,
ActionType.INTEGRATE_BATCHES,
ActionType.CLUSTER_CELLS,
ActionType.DIFFERENTIAL_EXPRESSION,
ActionType.PATHWAY_ENRICHMENT,
ActionType.MARKER_SELECTION,
ActionType.TRAJECTORY_ANALYSIS,
ActionType.REGULATORY_NETWORK_INFERENCE,
ActionType.SYNTHESIZE_CONCLUSION,
]
MODEL_RESPONSE_PREVIEW_CHARS = int(
os.getenv("RUN_AGENT_MODEL_RESPONSE_PREVIEW_CHARS", "240")
)
def compact_preview(value: Any, max_chars: int = 160) -> str:
try:
text = json.dumps(value, ensure_ascii=True, sort_keys=True)
except TypeError:
text = str(value)
text = re.sub(r"\s+", " ", text).strip()
if len(text) <= max_chars:
return text
return text[: max_chars - 3] + "..."
def format_observation(obs: ExperimentObservation) -> str:
parts = [
f"TASK: {obs.task.problem_statement}",
f"Organism: {obs.task.organism} | Tissue: {obs.task.tissue}",
f"Conditions: {', '.join(obs.task.conditions) or 'N/A'}",
f"Step: {obs.step_index} | Budget: ${obs.resource_usage.budget_remaining:,.0f} | Time: {obs.resource_usage.time_remaining_days:.0f}d",
]
context = build_agent_observation_context(obs, max_tools=5, max_assays=2)
if context:
parts.append(context)
if obs.pipeline_history:
last5 = obs.pipeline_history[-5:]
parts.append("Recent history:")
for h in last5:
tag = "OK" if h.success else "FAIL"
line = f" [{tag}] {h.action_type.value}"
if h.method:
line += f" ({h.method})"
line += f": {h.output_summary[:80]}"
parts.append(line)
completed = {h.action_type for h in obs.pipeline_history if h.success}
if completed:
parts.append(f"Completed steps (do NOT repeat): {', '.join(sorted(a.value for a in completed))}")
remaining = [a.value for a in STANDARD_PIPELINE_ORDER if a not in completed]
if remaining:
parts.append(f"Remaining steps (choose one): {', '.join(remaining)}")
if obs.latest_output and obs.latest_output.data:
parts.append(
f"Latest data: {compact_preview(obs.latest_output.data, 200)}"
)
if obs.rule_violations:
parts.append(f"VIOLATIONS: {obs.rule_violations}")
if obs.discovered_markers:
parts.append(f"Markers found so far: {obs.discovered_markers[:5]}")
parts.append(
'Output ONLY a single JSON object with these exact keys, no comments, no extra text:\n'
'{"action_type": "<one of the remaining steps>", "method": null, "parameters": {}, "justification": "<why>", "confidence": 0.8}'
)
return "\n".join(parts)
def _repair_truncated_json(text: str) -> Optional[str]:
"""Try to repair JSON truncated mid-value (common with small LLMs)."""
s = text.strip()
if not s.startswith("{"):
return None
# Drop dangling partial keys or empty key/value stubs at the tail.
s = re.sub(r',\s*"[^"\n]*$', '', s)
s = re.sub(r',\s*"[^"\n]*"\s*:\s*$', '', s)
in_string = False
escape = False
for ch in s:
if escape:
escape = False
continue
if ch == "\\":
escape = True
continue
if ch == '"':
in_string = not in_string
if in_string:
s += '"'
open_braces = s.count("{") - s.count("}")
open_brackets = s.count("[") - s.count("]")
s += "]" * max(0, open_brackets)
s += "}" * max(0, open_braces)
try:
obj = json.loads(s)
if isinstance(obj, dict):
return s
except json.JSONDecodeError:
pass
s = re.sub(r',\s*([}\]])', r'\1', s)
try:
obj = json.loads(s)
if isinstance(obj, dict):
return s
except json.JSONDecodeError:
pass
return None
def _normalize_jsonish_text(text: str) -> str:
"""Normalize common near-JSON artifacts emitted by small local models."""
text = _strip_js_comments(text)
text = re.sub(r'(?<=:\s)\bNone\b', 'null', text)
text = re.sub(r'(?<=:\s)\bTrue\b', 'true', text)
text = re.sub(r'(?<=:\s)\bFalse\b', 'false', text)
text = re.sub(r'"([^"\n]+?):"\s*,', r'"\1": "",', text)
return text
def _strip_js_comments(text: str) -> str:
"""Remove // and /* */ comments that small LLMs inject into JSON."""
text = re.sub(r'//[^\n]*', '', text)
text = re.sub(r'/\*.*?\*/', '', text, flags=re.DOTALL)
return text
def extract_json_object(text: str) -> Optional[Dict[str, Any]]:
stripped = _normalize_jsonish_text(text).strip()
if stripped.startswith('"') and stripped.endswith('"'):
try:
unwrapped = json.loads(stripped)
except json.JSONDecodeError:
unwrapped = None
if isinstance(unwrapped, str):
stripped = _normalize_jsonish_text(unwrapped).strip()
fence_prefix = "```"
if stripped.startswith(fence_prefix) and stripped.endswith(fence_prefix):
lines = stripped.splitlines()
if len(lines) >= 3:
stripped = "\n".join(lines[1:-1]).strip()
candidates: List[str] = [stripped]
start = stripped.find("{")
while start != -1:
depth = 0
for idx in range(start, len(stripped)):
char = stripped[idx]
if char == "{":
depth += 1
elif char == "}":
depth -= 1
if depth == 0:
candidates.append(stripped[start:idx + 1])
break
start = stripped.find("{", start + 1)
repaired = None
first_brace = stripped.find("{")
if first_brace != -1:
repaired = _repair_truncated_json(stripped[first_brace:])
if repaired is not None:
candidates.append(repaired)
candidates.sort(key=len, reverse=True)
for candidate in candidates:
try:
parsed = json.loads(candidate)
except json.JSONDecodeError:
continue
if isinstance(parsed, dict):
return parsed
return None
def _edit_distance(a: str, b: str) -> int:
if len(a) < len(b):
return _edit_distance(b, a)
if not b:
return len(a)
prev = list(range(len(b) + 1))
for i, ca in enumerate(a):
curr = [i + 1]
for j, cb in enumerate(b):
curr.append(min(prev[j + 1] + 1, curr[j] + 1, prev[j] + (ca != cb)))
prev = curr
return prev[-1]
def get_payload_value(payload: Dict[str, Any], *names: str) -> Any:
for name in names:
if name in payload:
return payload[name]
lowered = {
str(key).lower(): value
for key, value in payload.items()
}
for name in names:
if name.lower() in lowered:
return lowered[name.lower()]
for key, value in lowered.items():
for name in names:
threshold = max(2, len(name) // 3)
if _edit_distance(key, name.lower()) <= threshold:
return value
return None
def normalize_optional_string(value: Any) -> Optional[str]:
if value is None or isinstance(value, bool):
return None
if isinstance(value, str):
value = value.strip()
return value or None
if isinstance(value, (int, float)):
return str(value)
return compact_preview(value, 80)
def normalize_action_type(raw_action_type: Any) -> Optional[str]:
if not isinstance(raw_action_type, str):
return None
candidate = raw_action_type.strip().lower()
if candidate in ACTION_TYPES:
return candidate
if candidate in ACTION_TYPE_ALIASES:
return ACTION_TYPE_ALIASES[candidate]
candidate = re.sub(r"[^a-z0-9]+", "_", candidate).strip("_")
if candidate in ACTION_TYPES:
return candidate
if candidate in ACTION_TYPE_ALIASES:
return ACTION_TYPE_ALIASES[candidate]
heuristics = [
(("collect", "sample"), ActionType.COLLECT_SAMPLE.value),
(("library",), ActionType.PREPARE_LIBRARY.value),
(("sequence",), ActionType.SEQUENCE_CELLS.value),
(("qc",), ActionType.RUN_QC.value),
(("quality", "control"), ActionType.RUN_QC.value),
(("filter",), ActionType.FILTER_DATA.value),
(("normal",), ActionType.NORMALIZE_DATA.value),
(("integrat", "batch"), ActionType.INTEGRATE_BATCHES.value),
(("cluster",), ActionType.CLUSTER_CELLS.value),
(("differential", "expression"), ActionType.DIFFERENTIAL_EXPRESSION.value),
(("pathway",), ActionType.PATHWAY_ENRICHMENT.value),
(("trajectory",), ActionType.TRAJECTORY_ANALYSIS.value),
(("network",), ActionType.REGULATORY_NETWORK_INFERENCE.value),
(("marker",), ActionType.MARKER_SELECTION.value),
(("validat", "marker"), ActionType.VALIDATE_MARKER.value),
(("followup",), ActionType.DESIGN_FOLLOWUP.value),
(("review",), ActionType.REQUEST_SUBAGENT_REVIEW.value),
(("conclusion",), ActionType.SYNTHESIZE_CONCLUSION.value),
]
for fragments, normalized in heuristics:
if all(fragment in candidate for fragment in fragments):
return normalized
return None
def should_block_failed_reattempt(
history: List[Any], action_type: ActionType
) -> bool:
last_failed_idx = None
last_success_idx = None
for idx, record in enumerate(history):
if record.action_type != action_type:
continue
if record.success:
last_success_idx = idx
else:
last_failed_idx = idx
if last_failed_idx is None:
return False
# Allow retry after the same action has already succeeded once, or after the
# pipeline made progress with a different successful step since the failure.
if last_success_idx is not None and last_success_idx > last_failed_idx:
return False
for record in history[last_failed_idx + 1:]:
if record.success and record.action_type != action_type:
return False
return True
def parse_action(text: str) -> Optional[ExperimentAction]:
d = extract_json_object(text)
if d is not None:
action_type = normalize_action_type(get_payload_value(d, "action_type"))
if action_type is None:
pass
else:
parameters = get_payload_value(d, "parameters", "params") or {}
if not isinstance(parameters, dict):
parameters = {}
confidence = get_payload_value(d, "confidence")
if confidence is None:
confidence = 0.5
try:
confidence = float(confidence)
except (TypeError, ValueError):
confidence = 0.5
justification = get_payload_value(
d, "justification", "justifyement", "reasoning", "rationale", "reason"
)
if justification is not None and not isinstance(justification, str):
justification = compact_preview(justification, 200)
method = normalize_optional_string(get_payload_value(d, "method"))
return ExperimentAction(
action_type=ActionType(action_type),
method=method,
parameters=parameters,
justification=justification,
confidence=min(1.0, max(0.0, confidence)),
)
action_match = re.search(
r'["\']action_type["\']\s*:\s*["\']([^"\']+)',
text,
re.IGNORECASE,
)
if not action_match:
return None
action_type = normalize_action_type(action_match.group(1))
if action_type is None:
return None
method_match = re.search(
r'["\']method["\']\s*:\s*("((?:[^"\\]|\\.)*)"|null|none|true|false|-?\d+(?:\.\d+)?)',
text,
re.IGNORECASE,
)
confidence_match = re.search(
r'["\']confidence["\']\s*:\s*([0-9]*\.?[0-9]+)',
text,
re.IGNORECASE,
)
justification_match = re.search(
r'["\'](?:justif\w*|reasoning|rationale|reason)["\']\s*:\s*"((?:[^"\\]|\\.)*)',
text,
re.DOTALL | re.IGNORECASE,
)
confidence = 0.5
if confidence_match:
try:
confidence = float(confidence_match.group(1))
except ValueError:
confidence = 0.5
justification = None
if justification_match:
try:
justification = json.loads(f'"{justification_match.group(1)}"')
except json.JSONDecodeError:
justification = justification_match.group(1)
method = None
if method_match:
raw_method = method_match.group(1)
if raw_method.startswith('"') and raw_method.endswith('"'):
try:
method = json.loads(raw_method)
except json.JSONDecodeError:
method = raw_method.strip('"')
elif raw_method.lower() not in {"null", "none", "true", "false"}:
method = raw_method
method = normalize_optional_string(method)
return ExperimentAction(
action_type=ActionType(action_type),
method=method,
parameters={},
justification=justification,
confidence=min(1.0, max(0.0, confidence)),
)
def should_force_terminal_conclusion(
action: ExperimentAction,
completed_types: set[ActionType],
) -> bool:
meta_repeatables = {
ActionType.DESIGN_FOLLOWUP,
ActionType.REQUEST_SUBAGENT_REVIEW,
}
return (
action.action_type in meta_repeatables
and action.action_type in completed_types
and ActionType.SYNTHESIZE_CONCLUSION not in completed_types
)
def _unique_nonempty(items: List[str], limit: int = 5) -> List[str]:
seen: set[str] = set()
result: List[str] = []
for raw in items:
value = normalize_optional_string(raw)
if not value:
continue
key = value.upper()
if key in seen:
continue
seen.add(key)
result.append(value)
if len(result) >= limit:
break
return result
def _infer_conclusion_evidence(
obs: ExperimentObservation,
) -> tuple[List[str], List[str], Dict[str, float]]:
top_markers = _unique_nonempty(list(obs.discovered_markers), limit=5)
causal_mechanisms = _unique_nonempty(list(obs.candidate_mechanisms), limit=5)
predicted_pathways: Dict[str, float] = {}
for output in reversed(obs.all_outputs):
if not output.success:
continue
data = output.data or {}
if not top_markers:
if output.output_type == OutputType.MARKER_RESULT:
top_markers = _unique_nonempty(list(data.get("markers", [])), limit=5)
elif output.output_type == OutputType.DE_RESULT:
top_markers = _unique_nonempty(
[item.get("gene") for item in data.get("top_genes", []) if isinstance(item, dict)],
limit=5,
)
if output.output_type == OutputType.PATHWAY_RESULT and not predicted_pathways:
for item in data.get("top_pathways", []):
if not isinstance(item, dict):
continue
pathway = normalize_optional_string(item.get("pathway"))
score = item.get("score")
if pathway and isinstance(score, (int, float)):
predicted_pathways[pathway] = float(score)
if len(predicted_pathways) >= 5:
break
if not causal_mechanisms:
if output.output_type == OutputType.PATHWAY_RESULT:
causal_mechanisms = _unique_nonempty(
[item.get("pathway") for item in data.get("top_pathways", []) if isinstance(item, dict)],
limit=5,
)
elif output.output_type == OutputType.NETWORK_RESULT:
causal_mechanisms = _unique_nonempty(
list(data.get("top_regulators", [])),
limit=5,
)
if top_markers and causal_mechanisms and predicted_pathways:
break
return top_markers, causal_mechanisms, predicted_pathways
def ensure_conclusion_claims(
obs: ExperimentObservation,
action: ExperimentAction,
) -> ExperimentAction:
if action.action_type != ActionType.SYNTHESIZE_CONCLUSION:
return action
parameters = dict(action.parameters or {})
raw_claims = parameters.get("claims")
if isinstance(raw_claims, list) and raw_claims:
normalized_claims = [claim for claim in raw_claims if isinstance(claim, dict)]
if normalized_claims:
parameters["claims"] = normalized_claims
if parameters != action.parameters:
return action.model_copy(update={"parameters": parameters})
return action
top_markers, causal_mechanisms, predicted_pathways = _infer_conclusion_evidence(obs)
claim_type = "causal" if causal_mechanisms else "correlational"
conditions = " vs ".join(obs.task.conditions[:2]) if obs.task.conditions else "the task conditions"
claim = action.justification or f"Final synthesis for {conditions}."
parameters["claims"] = [{
"top_markers": top_markers,
"causal_mechanisms": causal_mechanisms,
"predicted_pathways": predicted_pathways,
"confidence": action.confidence,
"claim_type": claim_type,
"claim": claim,
}]
if not action.justification:
action = action.model_copy(update={"justification": claim})
return action.model_copy(update={"parameters": parameters})
def write_dashboard_state(
env: BioExperimentEnvironment,
obs: ExperimentObservation,
*,
step: int,
cumulative_reward: float,
model_response: str = "",
model_thinking: str = "",
action: Optional[ExperimentAction] = None,
gen_time: float = 0.0,
episode_done: bool = False,
) -> None:
"""Serialise the full world state (observable + latent) for the dashboard."""
latent = env._latent
snapshot: Dict[str, Any] = {
"timestamp": time.time(),
"step": step,
"episode_done": episode_done,
"cumulative_reward": cumulative_reward,
"gen_time_s": round(gen_time, 2),
"model_response_raw": model_response[:600],
"model_thinking": model_thinking[:800],
"thinking_enabled": ENABLE_THINKING,
}
snapshot["task"] = {
"problem_statement": obs.task.problem_statement,
"organism": obs.task.organism,
"tissue": obs.task.tissue,
"modality": obs.task.modality,
"conditions": obs.task.conditions,
"budget_limit": obs.task.budget_limit,
"time_limit_days": obs.task.time_limit_days,
}
snapshot["resources"] = {
"budget_used": round(obs.resource_usage.budget_used, 2),
"budget_remaining": round(obs.resource_usage.budget_remaining, 2),
"time_used_days": round(obs.resource_usage.time_used_days, 1),
"time_remaining_days": round(obs.resource_usage.time_remaining_days, 1),
"samples_consumed": obs.resource_usage.samples_consumed,
"compute_hours_used": round(obs.resource_usage.compute_hours_used, 2),
}
snapshot["pipeline_history"] = [
{
"step_index": h.step_index,
"action_type": h.action_type.value,
"method": h.method,
"output_summary": h.output_summary[:120],
"success": h.success,
"quality_score": round(h.quality_score, 3),
"resource_cost": round(h.resource_cost, 2),
"time_cost_days": round(h.time_cost_days, 1),
}
for h in obs.pipeline_history
]
if action:
snapshot["current_action"] = {
"action_type": action.action_type.value,
"method": action.method,
"parameters": action.parameters,
"justification": action.justification,
"confidence": action.confidence,
}
if obs.latest_output:
lo = obs.latest_output
snapshot["latest_output"] = {
"summary": lo.summary,
"success": lo.success,
"quality_score": round(lo.quality_score, 3),
"uncertainty": round(lo.uncertainty, 3),
"warnings": lo.warnings,
"data_preview": compact_preview(lo.data, 300) if lo.data else None,
}
snapshot["discovered_markers"] = obs.discovered_markers[:20]
snapshot["candidate_mechanisms"] = obs.candidate_mechanisms[:20]
snapshot["rule_violations"] = obs.rule_violations
snapshot["uncertainty_summary"] = {
k: round(v, 3) for k, v in obs.uncertainty_summary.items()
}
snapshot["reward_breakdown"] = {
k: round(v, 4) for k, v in obs.step_reward_breakdown.items()
}
if obs.conclusions:
snapshot["conclusions"] = [
{
"claim": c.claim,
"claim_type": c.claim_type,
"confidence": c.confidence,
"top_markers": c.top_markers,
"causal_mechanisms": c.causal_mechanisms,
"predicted_pathways": c.predicted_pathways,
}
for c in obs.conclusions
]
if latent:
bio = latent.biology
snapshot["latent"] = {
"cell_populations": [
{
"name": cp.name,
"proportion": round(cp.proportion, 3),
"marker_genes": cp.marker_genes[:8],
"state": cp.state,
}
for cp in bio.cell_populations
],
"true_markers": bio.true_markers,
"causal_mechanisms": bio.causal_mechanisms,
"true_pathways": {
k: round(v, 3) for k, v in list(bio.true_pathways.items())[:15]
},
"true_de_genes_count": sum(
len(genes) for genes in bio.true_de_genes.values()
),
"true_regulatory_network_size": sum(
len(targets) for targets in bio.true_regulatory_network.values()
),
"confounders": bio.confounders,
"n_true_cells": bio.n_true_cells,
"technical": {
"ambient_rna_fraction": latent.technical.ambient_rna_fraction,
"doublet_rate": latent.technical.doublet_rate,
"dropout_rate": latent.technical.dropout_rate,
"sample_quality": latent.technical.sample_quality,
"library_complexity": latent.technical.library_complexity,
"capture_efficiency": latent.technical.capture_efficiency,
},
"progress": latent.progress.model_dump(),
"hidden_failure_conditions": latent.hidden_failure_conditions,
}
try:
DASHBOARD_STATE_PATH.write_text(
json.dumps(snapshot, indent=2, default=str), encoding="utf-8"
)
except Exception:
pass
def log(msg: str) -> None:
print(msg, flush=True)
def build_observation_prompt(obs: ExperimentObservation) -> str:
return format_observation(obs)
def run_with_pipeline(pipe, prompt: str) -> str:
try:
_pipe_max = 2048 if ENABLE_THINKING else 300
result = pipe(prompt, max_new_tokens=_pipe_max, return_full_text=False)
except Exception:
return ""
if isinstance(result, list) and result:
result = result[0]
if isinstance(result, dict):
text = result.get("generated_text") or result.get("text") or result.get("answer")
elif isinstance(result, str):
text = result
else:
text = ""
return text.strip() if isinstance(text, str) else ""
def resolve_torch_runtime() -> Dict[str, Any]:
use_cuda = torch.cuda.is_available()
bf16 = bool(getattr(torch.cuda, "is_bf16_supported", lambda: False)()) if use_cuda else False
dtype = torch.bfloat16 if bf16 else (
torch.float16 if use_cuda else torch.float32
)
return {
"use_cuda": use_cuda,
"device": "cuda:0" if use_cuda else "cpu",
"dtype": dtype,
"device_map": "auto" if use_cuda else None,
"device_name": torch.cuda.get_device_name(0) if use_cuda else "cpu",
}
def main():
tokenizer = None
model = None
eos_ids: List[int] = []
active_pipeline = None
runtime = resolve_torch_runtime()
log(
f"Using local model runtime: device={runtime['device']} "
f"name={runtime['device_name']} dtype={runtime['dtype']}"
)
if USE_PIPELINE:
log(f"Loading pipeline ({PIPELINE_TASK}) for {MODEL_ID} ...")
try:
active_pipeline = pipeline(
PIPELINE_TASK,
model=MODEL_ID,
trust_remote_code=True,
dtype=runtime["dtype"],
device=0 if runtime["use_cuda"] else -1,
)
log("Pipeline loaded.")
except Exception as exc:
log(f"Pipeline load failed ({exc}), falling back to tokenizer+model.")
if active_pipeline is None:
log(f"Loading tokenizer for {MODEL_ID} ...")
tokenizer = AutoTokenizer.from_pretrained(
MODEL_ID, trust_remote_code=True,
)
log("Tokenizer loaded. Loading model (this may download files on first run) ...")
model = AutoModelForCausalLM.from_pretrained(
MODEL_ID,
dtype=runtime["dtype"],
device_map=runtime["device_map"],
trust_remote_code=True,
)
log(f"Model loaded. Device: {model.device}")
if tokenizer.eos_token_id is not None:
eos_ids.append(tokenizer.eos_token_id)
extra = tokenizer.convert_tokens_to_ids(["<|im_end|>", "<|endoftext|>"])
for tid in extra:
if isinstance(tid, int) and tid not in eos_ids:
eos_ids.append(tid)
log(f"EOS token ids: {eos_ids}")
def check_dashboard_command() -> Optional[Dict[str, Any]]:
"""Read and consume a command file written by the dashboard."""
try:
raw = DASHBOARD_CMD_PATH.read_text(encoding="utf-8")
try:
DASHBOARD_CMD_PATH.unlink(missing_ok=True)
except OSError:
# Windows: file may be locked by dashboard; still consumed
pass
return json.loads(raw)
except (FileNotFoundError, json.JSONDecodeError):
return None
def run_episode(
scenario_name: Optional[str] = None,
custom_ground_truth: Optional[Dict[str, Any]] = None,
):
env = BioExperimentEnvironment(scenario_name=scenario_name)
obs = env.reset()
if custom_ground_truth and env._latent:
gt = custom_ground_truth
bio = env._latent.biology
if gt.get("true_markers"):
bio.true_markers = gt["true_markers"]
if gt.get("causal_mechanisms"):
bio.causal_mechanisms = gt["causal_mechanisms"]
if gt.get("true_pathways"):
bio.true_pathways = {
k: float(v) for k, v in gt["true_pathways"].items()
}
log("\n" + "=" * 70)
log(f"TASK: {obs.task.problem_statement}")
log(f"Conditions: {obs.task.conditions}")
log(f"Budget: ${obs.task.budget_limit:,.0f} | Time: {obs.task.time_limit_days:.0f} days")
if ENABLE_THINKING:
log("Reasoning mode: ENABLED")
log("=" * 70)
cumulative_reward = 0.0
write_dashboard_state(env, obs, step=0, cumulative_reward=0.0)
for step in range(MAX_EPISODE_STEPS):
cmd = check_dashboard_command()
if cmd and cmd.get("action") == "restart":
log("\n[DASHBOARD] Restart requested — ending episode early.")
break
user_msg = build_observation_prompt(obs)
messages = [
{"role": "system", "content": SYSTEM_PROMPT},
{"role": "user", "content": user_msg},
]
if active_pipeline is not None:
prompt = f"{SYSTEM_PROMPT}\n\n{user_msg}"
else:
try:
prompt = tokenizer.apply_chat_template(
messages,
tokenize=False,
add_generation_prompt=True,
enable_thinking=ENABLE_THINKING,
)
except TypeError:
prompt = tokenizer.apply_chat_template(
messages,
tokenize=False,
add_generation_prompt=True,
)
t0 = time.time()
if active_pipeline is not None:
response = run_with_pipeline(active_pipeline, prompt)
if not response:
response = format_observation(obs)
else:
assert tokenizer is not None and model is not None
inputs = tokenizer(prompt, return_tensors="pt").to(model.device)
n_input = inputs["input_ids"].shape[1]
max_new = 2048 if ENABLE_THINKING else 300
with torch.no_grad():
output_ids = model.generate(
**inputs,
max_new_tokens=max_new,
do_sample=True,
temperature=0.7,
top_p=0.8,
top_k=20,
repetition_penalty=1.3,
eos_token_id=eos_ids if eos_ids else None,
)
new_tokens = output_ids[0][n_input:]
response = tokenizer.decode(new_tokens, skip_special_tokens=True).strip()
gen_time = time.time() - t0
thinking = ""
if ENABLE_THINKING:
think_match = re.search(
r"<think>(.*?)</think>", response, re.DOTALL
)
if think_match:
thinking = think_match.group(1).strip()
response = response[think_match.end():].strip()
elif response.startswith("<think>"):
parts = response.split("</think>", 1)
if len(parts) == 2:
thinking = parts[0].replace("<think>", "").strip()
response = parts[1].strip()
is_last_step = (step == MAX_EPISODE_STEPS - 1)
action = parse_action(response)
if action is None:
if is_last_step:
log(f"\n [!] Parse failed on final step — forcing synthesize_conclusion.")
action = ExperimentAction(
action_type=ActionType.SYNTHESIZE_CONCLUSION,
justification="forced terminal conclusion",
confidence=0.5,
)
else:
log(f"\n [!] Parse failed, skipping step. Raw: {response[:150]}")
continue
completed_types = {
r.action_type for r in obs.pipeline_history if r.success
}
failed_types = {
r.action_type
for r in obs.pipeline_history
if not r.success
}
if should_force_terminal_conclusion(action, completed_types):
log(
f"\n [!] repeated completed meta step {action.action_type.value} "
f"— forcing synthesize_conclusion."
)
action = ExperimentAction(
action_type=ActionType.SYNTHESIZE_CONCLUSION,
justification="repeated completed meta step forced terminal conclusion",
confidence=action.confidence,
)
completed_types = {
r.action_type for r in obs.pipeline_history if r.success
}
skip_reason = None
if action.action_type in completed_types:
skip_reason = (
f"blocked repeat of completed step {action.action_type.value}"
)
elif action.action_type in failed_types:
if should_block_failed_reattempt(
obs.pipeline_history, action.action_type
):
skip_reason = (
f"blocked re-attempt of failed step {action.action_type.value}"
)
if skip_reason:
if is_last_step:
log(f"\n [!] {skip_reason} on final step — forcing synthesize_conclusion.")
action = ExperimentAction(
action_type=ActionType.SYNTHESIZE_CONCLUSION,
justification="forced terminal conclusion",
confidence=0.5,
)
else:
log(f"\n [!] {skip_reason}, skipping step.")
continue
if is_last_step and action.action_type != ActionType.SYNTHESIZE_CONCLUSION:
log(f"\n [!] Final step — overriding {action.action_type.value} with synthesize_conclusion.")
action = ExperimentAction(
action_type=ActionType.SYNTHESIZE_CONCLUSION,
justification="forced terminal conclusion",
confidence=action.confidence,
)
action = ensure_conclusion_claims(obs, action)
log(f"\nStep {step + 1}: {action.action_type.value} ({gen_time:.1f}s)")
if thinking:
log(f" Thinking: {thinking[:200]}")
if action.justification:
log(f" Rationale: {action.justification}")
else:
log(" Rationale: [model did not provide one]")
if action.parameters:
log(f" Parameters: {compact_preview(action.parameters, 200)}")
elif not action.justification and response:
log(
f" Model response: "
f"{compact_preview(response, MODEL_RESPONSE_PREVIEW_CHARS)}"
)
obs = env.step(action)
if obs.latest_output:
lo = obs.latest_output
status = "OK" if lo.success else "FAIL"
log(f" [{status}] {lo.summary}")
if lo.warnings:
log(f" Warnings: {lo.warnings}")
step_reward = obs.reward
cumulative_reward += step_reward
log(f" Reward: {step_reward:+.3f} (cum: {cumulative_reward:+.3f})")
log(f" Budget: ${obs.resource_usage.budget_remaining:,.0f} | Time: {obs.resource_usage.time_remaining_days:.0f}d")
write_dashboard_state(
env, obs,
step=step + 1,
cumulative_reward=cumulative_reward,
model_response=response,
model_thinking=thinking,
action=action,
gen_time=gen_time,
episode_done=obs.done,
)
if obs.rule_violations:
log(f" Violations: {obs.rule_violations}")
if obs.done:
break
log(f"\n{'=' * 70}")
log("EPISODE COMPLETE" if obs.done else f"MAX STEPS ({MAX_EPISODE_STEPS})")
log(f" Steps: {obs.step_index}")
log(f" Total reward: {cumulative_reward:+.3f}")
log(f" Budget used: ${obs.resource_usage.budget_used:,.0f}")
log(f" Time used: {obs.resource_usage.time_used_days:.0f} days")
if obs.conclusions:
log(" Conclusions:")
for c in obs.conclusions:
log(f" [{c.claim_type}, conf={c.confidence:.2f}] {c.claim}")
if c.top_markers:
log(f" Markers: {c.top_markers}")
if c.causal_mechanisms:
log(f" Mechanisms: {c.causal_mechanisms}")
if c.predicted_pathways:
log(f" Pathways: {c.predicted_pathways}")
log("=" * 70)
try:
DASHBOARD_CMD_PATH.unlink(missing_ok=True)
except OSError:
pass
run_episode()
while True:
log("\nWaiting for dashboard command (restart / new task) ...")
while True:
cmd = check_dashboard_command()
if cmd:
break
time.sleep(1.0)
action_type = cmd.get("action", "restart")
if action_type == "quit":
log("Quit requested.")
break
scenario = cmd.get("scenario_name")
ground_truth = cmd.get("ground_truth")
log(f"\n[DASHBOARD] {action_type} — scenario={scenario}")
run_episode(scenario_name=scenario, custom_ground_truth=ground_truth)
if __name__ == "__main__":
main()