File size: 9,205 Bytes
00b1e78
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
from flask import Flask, render_template, request, flash, redirect, url_for
import numpy as np
import pickle

app = Flask(__name__)
app.secret_key = 'your_secret_key_here'  # Replace with a strong secret key

def predict_disease(patient_data):
    """

    Predicts disease risks based on patient data.

    Loads pre-trained models and scalers, prepares features, and returns a risk dictionary.

    """
    try:
        # Load models
        heart_model = pickle.load(open('heart_rf_model.pkl', 'rb'))
        diabetes_model = pickle.load(open('diabetes_model.pkl', 'rb'))
        cirrhosis_model = pickle.load(open('cirrhosis_model.pkl', 'rb'))
        hep_c_model = pickle.load(open('hep_c_model.pkl', 'rb'))

        # Load scalers
        heart_scaler = pickle.load(open('heart_scaler.pkl', 'rb'))
        diabetes_scaler = pickle.load(open('diabetes_scaler.pkl', 'rb'))
        cirrhosis_scaler = pickle.load(open('cirrhosis_scaler.pkl', 'rb'))
        hep_c_scaler = pickle.load(open('hep_c_scaler.pkl', 'rb'))

        # Heart Disease Features
        heart_features = np.array([[
            patient_data.get('Age', 55),
            patient_data.get('Sex', 1),
            patient_data.get('cp', 0),
            patient_data.get('BP', 130),
            patient_data.get('Cholesterol', 200),
            patient_data.get('FBS', 0),
            patient_data.get('EKG', 0),
            patient_data.get('MaxHR', 150),
            patient_data.get('ExerciseAngina', 0),
            patient_data.get('STdepression', 0.0),
            patient_data.get('STslope', 0),
            patient_data.get('Vessels', 0),
            patient_data.get('Thallium', 2)
        ]])

        # Diabetes Features – only scaling Age
        diabetes_features = np.array([[
            1 if patient_data.get('Polyuria', 0) == 1 else 0,
            1 if patient_data.get('Polydipsia', 0) == 1 else 0,
            patient_data.get('Age', 55),  # Age will be scaled
            1 if patient_data.get('Gender', 'Male') == 'Male' else 0,
            1 if patient_data.get('partial_paresis', 0) == 1 else 0,
            1 if patient_data.get('sudden_weight_loss', 0) == 1 else 0,
            1 if patient_data.get('Irritability', 0) == 1 else 0,
            1 if patient_data.get('delayed_healing', 0) == 1 else 0,
            1 if patient_data.get('Alopecia', 0) == 1 else 0,
            1 if patient_data.get('Itching', 0) == 1 else 0
        ]])
        # Scale Age for diabetes
        age_scaled = diabetes_scaler.transform([[patient_data.get('Age', 55)]])
        diabetes_features[0, 2] = age_scaled[0, 0]

        # Cirrhosis Features
        cirrhosis_features = np.array([[
            patient_data.get('Bilirubin', 1.2),
            patient_data.get('Albumin', 3.8),
            patient_data.get('Copper', 80),
            patient_data.get('Alk_Phos', 70),
            patient_data.get('SGOT', 40),
            patient_data.get('Tryglicerides', 150),
            patient_data.get('Platelets', 250),
            patient_data.get('Prothrombin', 11),
            patient_data.get('Stage', 1),
            patient_data.get('Age', 55),
            patient_data.get('Sex', 1),
            patient_data.get('Ascites', 0),
            patient_data.get('Hepatomegaly', 0),
            patient_data.get('Spiders', 0),
            patient_data.get('Edema', 0)
        ]])

        # Hepatitis C Features
        hep_c_features = np.array([[
            patient_data.get('Age', 55),
            patient_data.get('Sex', 1),
            patient_data.get('ALB', 4.0),
            patient_data.get('ALP', 70),
            patient_data.get('ALT', 45),
            patient_data.get('AST', 38),
            patient_data.get('BIL', 0.8),
            patient_data.get('CHE', 8000),
            patient_data.get('CHOL', 180),
            patient_data.get('CREA', 0.9),
            patient_data.get('GGT', 30),
            patient_data.get('PROT', 7.0)
        ]])

        # Scale features
        heart_scaled = heart_scaler.transform(heart_features)
        cirrhosis_scaled = cirrhosis_scaler.transform(cirrhosis_features)
        hep_c_scaled = hep_c_scaler.transform(hep_c_features)

        # Get prediction probabilities
        heart_prob = heart_model.predict_proba(heart_scaled)[:, 1][0]
        diabetes_prob = diabetes_model.predict_proba(diabetes_features)[:, 1][0]
        cirrhosis_prob = cirrhosis_model.predict_proba(cirrhosis_scaled)[:, 1][0]
        hep_c_prob = hep_c_model.predict_proba(hep_c_scaled)[:, 1][0]

        # Compute overall risk score
        final_score = (
            (0.30 * heart_prob) +
            (0.25 * diabetes_prob) +
            (0.25 * cirrhosis_prob) +
            (0.20 * hep_c_prob)
        )

        return {
            'Heart Disease': {'Risk': 'High' if heart_prob > 0.5 else 'Low', 'Probability': round(heart_prob, 3)},
            'Diabetes': {'Risk': 'High' if diabetes_prob > 0.5 else 'Low', 'Probability': round(diabetes_prob, 3)},
            'Cirrhosis': {'Risk': 'High' if cirrhosis_prob > 0.5 else 'Low', 'Probability': round(cirrhosis_prob, 3)},
            'Hepatitis C': {'Risk': 'High' if hep_c_prob > 0.5 else 'Low', 'Probability': round(hep_c_prob, 3)},
            'Overall Risk Score': round(final_score, 3)
        }

    except Exception as e:
        raise Exception(f"Error in prediction: {str(e)}")

@app.route('/', methods=['GET', 'POST'])
def index():
    result = None
    if request.method == 'POST':
        try:
            # Collect input parameters from the form
            patient_data = {
                # General / Heart Disease
                'Age': int(request.form.get('Age', 55)),
                'Sex': int(request.form.get('Sex', 1)),
                'cp': int(request.form.get('cp', 0)),
                'BP': float(request.form.get('BP', 130)),
                'Cholesterol': float(request.form.get('Cholesterol', 200)),
                'FBS': int(request.form.get('FBS', 0)),
                'EKG': int(request.form.get('EKG', 0)),
                'MaxHR': int(request.form.get('MaxHR', 150)),
                'ExerciseAngina': int(request.form.get('ExerciseAngina', 0)),
                'STdepression': float(request.form.get('STdepression', 0.0)),
                'STslope': int(request.form.get('STslope', 0)),
                'Vessels': int(request.form.get('Vessels', 0)),
                'Thallium': int(request.form.get('Thallium', 2)),

                # Diabetes
                'Polyuria': int(request.form.get('Polyuria', 0)),
                'Polydipsia': int(request.form.get('Polydipsia', 0)),
                'Gender': request.form.get('Gender', 'Male'),
                'partial_paresis': int(request.form.get('partial_paresis', 0)),
                'sudden_weight_loss': int(request.form.get('sudden_weight_loss', 0)),
                'Irritability': int(request.form.get('Irritability', 0)),
                'delayed_healing': int(request.form.get('delayed_healing', 0)),
                'Alopecia': int(request.form.get('Alopecia', 0)),
                'Itching': int(request.form.get('Itching', 0)),

                # Cirrhosis
                'Bilirubin': float(request.form.get('Bilirubin', 1.2)),
                'Albumin': float(request.form.get('Albumin', 3.8)),
                'Copper': float(request.form.get('Copper', 80)),
                'Alk_Phos': float(request.form.get('Alk_Phos', 70)),
                'SGOT': float(request.form.get('SGOT', 40)),
                'Tryglicerides': float(request.form.get('Tryglicerides', 150)),
                'Platelets': float(request.form.get('Platelets', 250)),
                'Prothrombin': float(request.form.get('Prothrombin', 11)),
                'Stage': int(request.form.get('Stage', 1)),
                'Ascites': int(request.form.get('Ascites', 0)),
                'Hepatomegaly': int(request.form.get('Hepatomegaly', 0)),
                'Spiders': int(request.form.get('Spiders', 0)),
                'Edema': int(request.form.get('Edema', 0)),

                # Hepatitis C
                'ALB': float(request.form.get('ALB', 4.0)),
                'ALP': float(request.form.get('ALP', 70)),
                'ALT': float(request.form.get('ALT', 45)),
                'AST': float(request.form.get('AST', 38)),
                'BIL': float(request.form.get('BIL_hep', 0.8)),  # To distinguish from cirrhosis bilirubin
                'CHE': float(request.form.get('CHE', 8000)),
                'CHOL': float(request.form.get('CHOL_hep', 180)),  # To distinguish from heart cholesterol
                'CREA': float(request.form.get('CREA', 0.9)),
                'GGT': float(request.form.get('GGT', 30)),
                'PROT': float(request.form.get('PROT_hep', 7.0))
            }

            # Get the prediction result
            result = predict_disease(patient_data)
        except Exception as e:
            flash(str(e))
    return render_template('index.html', result=result)

if __name__ == '__main__':
    app.run(debug=True, port=1234)