app.py

import gradio as gr
from utils import run_clinker

# css = """
# body, .gradio-container { background-color: #e0e0e0 !important; }
# .contain { background-color: #e0e0e0 !important; }
# /* give the plot panel a white card so the clinker viz has a clean background */
# div[data-testid="html"] { background: #ffffff; border-radius: 8px; padding: 4px; }
# """
with gr.Blocks(title="Clinker Gene Cluster Comparison", theme=gr.themes.Soft()) as demo:
    gr.Markdown(
        "# Clinker Gene Cluster Comparison\n"
        "Enter one NCBI nucleotide accession per line, then click **Run**."
    )

    with gr.Row():
        with gr.Column(scale=1):
            accessions_input = gr.Textbox(
                lines=6,
                placeholder="MH816969\nMH816970\n...",
                label="NCBI Accessions (one per line)",
            )
            fasta_input = gr.Textbox(
                lines=6,
                placeholder=">contig_1\nATGCATGCATGC...\n>contig_2\nGCTAGCTAGCTA...",
                label="Multi-FASTA sequences (optional — ORFs predicted automatically)",
            )
            run_btn = gr.Button("Run", variant="primary")

        with gr.Column(scale=3):
            html_output = gr.HTML(label="Clinker Output")

    run_btn.click(
        fn=run_clinker,
        inputs=[accessions_input, fasta_input],
        outputs=html_output,
    )

demo.launch()