# PHLAM (CPU) -- Hugging Face Space (Docker SDK), CPU-only free tier. FROM python:3.10-slim RUN useradd -m -u 1000 user USER user ENV HOME=/home/user \ PATH=/home/user/.local/bin:$PATH \ HF_HOME=/home/user/.cache/huggingface \ PYTHONUNBUFFERED=1 \ PORT=7860 \ ESM_MODEL=facebook/esm2_t12_35M_UR50D \ REFERENCE_DATA_DIR=/data/reference/ \ IMGVR_DATA_DIR=/data/imgvr_inphared \ MODELS_DATA_DIR=/data/models WORKDIR /home/user/app COPY --chown=user requirements.txt . RUN pip install --no-cache-dir --upgrade pip \ && pip install --no-cache-dir torch --index-url https://download.pytorch.org/whl/cpu \ && pip install --no-cache-dir -r requirements.txt # Bake the ESM-2 weights into the image so the first request isn't a cold download. RUN python -c "from transformers import AutoTokenizer, AutoModel; m='facebook/esm2_t12_35M_UR50D'; AutoTokenizer.from_pretrained(m); AutoModel.from_pretrained(m)" # reference_min.index / reference_min.parquet are NOT baked in -- they arrive # via hfmount at REFERENCE_DATA_DIR (mounted_drive/reference/reference/) when # the Space runs. COPY --chown=user . . EXPOSE 7860 # --timeout 900: /analyze's synchronous path (ESM/PHLAM load, annotation # retriever's first touch of reference_min.* on hfmount) can be slow on a # cold start over a network-mounted bucket -- this is gunicorn's worker # silence timeout, not a hard request cap; background jobs (neighbor # search, synteny) run in threads and never block a worker at all, so they # aren't bound by this regardless of how long the FAISS indexes take. CMD ["gunicorn", "app:app", \ "--workers", "1", "--threads", "4", "--worker-class", "gthread", \ "--timeout", "900", "--bind", "0.0.0.0:7860"]