reqs

README.md

@@ -36,3 +36,8 @@ uv sync
 uv run gradio app.py
 ```
 
+## Hugging Face Space dependencies
+
+HF Gradio Spaces install Python packages from `requirements.txt` during build.
+`uv.lock` is not used by the default Space launcher, so runtime dependencies
+needed by `app.py` (such as `rdkit`) must be listed in `requirements.txt`.

requirements.txt

@@ -0,0 +1,4 @@
+# Hugging Face Gradio Spaces install Python deps from requirements.txt.
+# Keep `uv` for local dev; this file ensures runtime deps are present on HF.
+rdkit
+pillow