{ "Metadata (not used for simulation)": { "description": "Human with single patch per wall, and growth driven by pressure overload (through Ras)", "references": [""], "notes": "" }, "Circulation": { "hr": 75, "sbv": 1500, "k": [0.10, 0.05, 0.10, 0.05, 0.30, 0.05, 0.10, 0.25] }, "Capacitances": { "cvp": 8.0, "cas": 1.12, "cvs": 70.0, "cap": 13.0 }, "Resistances": { "rvp": 0.015, "rcs": 0.090, "ras": 0.900, "rvs": 0.015, "rcp": 0.020, "rap": 0.300, "rav": 0.025, "rmvb": 1e20, "rtvb": 1e20 }, "Solver": { "cutoff": 0.01, "iter_max": 50, "n_inc": 1800 }, "Heart": { "patches": [0, 1, 2, 3, 4], "am_ref": [ 7920, 10800, 4160, 5520, 4000], "wv": [58200, 36368, 41896, 5752, 2552], "ls_ref": [2.0, 2.0, 2.0, 2.0, 2.0], "ls_eiso": [0.04, 0.04, 0.04, 0.04, 0.04], "lsc0": [1.51, 1.51, 1.51, 1.51, 1.51], "v_max": [7e-3, 7e-3, 7e-3, 14e-3, 14e-3], "tr": [0.25, 0.25, 0.25, 0.40, 0.40], "td": [0.25, 0.25, 0.25, 0.40, 0.40], "tad": [200, 200, 200, 80, 80], "sf_act": [0.150, 0.150, 0.150, 0.060, 0.060], "c_1": [1e-5, 1e-5, 1e-5, 1.60e-3, 1.60e-3], "c_3": [5.23e-4, 5.23e-4, 5.23e-4, 0.017e-3, 0.017e-3], "c_4": [10.0, 10.0, 10.0, 10.0, 10.0], "t_act": [100, 100, 100, 0, 0], "ischemic": [0, 0, 0, 0, 0] }, "Pericardium": { "thickness": 0.0, "c_1": 1.59e-1, "c_3": 8.41e-3, "c_4": 3.47e1, "pre_stretch": 1.0 }, "Growth": { "type": "transverse_jones", "time": [-1, 0, 1, 6, 11, 16, 21, 26, 31, 36, 41, 46, 51, 56, 61, 66, 71, 76, 81, 86, 91, 96, 101, 106, 111, 116, 121, 126, 131, 136, 141, 146, 151, 156, 161, 166, 171, 175, 181], "hr": [75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75, 75], "rmvb": [1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10, 1e10], "sbv": [1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800, 1800], "ras": [0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900, 0.900], "ischemic": [ { "ischemic": [0, 0, 0, 0, 0], "t_init": 0 } ], "t_act": [ { "t_act": [100, 100, 100, 0, 0], "t_init": 0 } ], "tau_f+": 1.0, "tau_f-" : 1e5, "tau_r+": 1e5, "tau_r-": 5.0, "gamma": 2.0, "theta_f_max": 2.25, "theta_f_min": 0.75, "theta_r_max": 1.5, "theta_r_min": 0.75, "t_mem": 10000, "growing_walls": [0, 1, 2] } }