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from PIL import Image
import tensorflow as tf
import google.generativeai as genai
import numpy as np
import os
import time
import requests
from bs4 import BeautifulSoup
import faiss
import pickle
import json
import logging
from typing import Dict, Any, Tuple
import sys
import dotenv
# Set up logging
logging.basicConfig(
level=logging.INFO,
format='%(asctime)s - %(name)s - %(levelname)s - %(message)s'
)
logger = logging.getLogger('bloodcell_app')
# Load environment variables
dotenv.load_dotenv()
# --- Page Configuration (MUST BE THE FIRST STREAMLIT COMMAND) ---
st.set_page_config(
page_title="AI Chat & Blood Classifier",
layout="wide",
initial_sidebar_state="auto"
)
# --- AgentPro Import Attempt ---
try:
# Try to import AgentPro
from AgentPro.agentpro import AgentPro
from AgentPro.agentpro.tools import AresInternetTool
# Initialize AgentPro for hospital search
tools = [AresInternetTool()]
agent = AgentPro(tools=tools)
logger.info("AgentPro initialized successfully with AresInternetTool")
hospital_search_available = True
except ImportError:
try:
sys.path.append(os.path.join(os.path.dirname(os.path.abspath(__file__)), "AgentPro"))
from agentpro import AgentPro
from agentpro.tools import AresInternetTool
# Initialize AgentPro for hospital search
tools = [AresInternetTool()]
agent = AgentPro(tools=tools)
logger.info("AgentPro initialized successfully with AresInternetTool")
hospital_search_available = True
except ImportError:
logger.warning("Unable to import AgentPro. Hospital search functionality will be disabled.")
# Create placeholder empty classes so the rest of the code can run
class AgentProPlaceholder:
def __init__(self, *args, **kwargs):
pass
def __call__(self, *args, **kwargs):
return "AgentPro is not available. Please check your installation."
class AresInternetToolPlaceholder:
def __init__(self):
self.name = "AresInternetTool"
self.description = "A tool for searching the internet (currently unavailable)"
AgentPro = AgentProPlaceholder
AresInternetTool = AresInternetToolPlaceholder
agent = None
hospital_search_available = False
except Exception as e:
logger.error(f"Error initializing AgentPro: {e}")
agent = None
hospital_search_available = False
# --- Hospital Search Functionality ---
# Constants for hospital search
HOSPITAL_CACHE_DURATION = 86400 # 24 hours in seconds
HOSPITAL_CACHE = {} # In-memory cache: {(disease, location): (timestamp, results)}
def search_hospitals(agent, disease: str, location: str, force_refresh: bool = False) -> str:
"""
Search for hospitals that specialize in treating a specific blood disease in a given location.
Args:
agent: The AgentPro instance to use for search
disease: The blood disease or indicator (e.g., "NPM1", "PML_RARA")
location: The city/location to search in (e.g., "Lahore")
force_refresh: Whether to force a fresh search, ignoring cache
Returns:
str: A formatted response with hospital information
"""
# Check cache first (if not forcing refresh)
cache_key = (disease, location)
if not force_refresh and cache_key in HOSPITAL_CACHE:
timestamp, results = HOSPITAL_CACHE[cache_key]
# If cache is still valid (less than CACHE_DURATION old)
if time.time() - timestamp < HOSPITAL_CACHE_DURATION:
logger.info(f"Using cached results for {disease} in {location}")
return results
try:
# Format the query for better results
if disease in ["NPM1", "PML_RARA", "RUNX1_RUNX1T1"]:
# For genetic markers, add context
query = (
f"Find hospitals or medical centers in {location}, Pakistan that specialize in "
f"hematology and can treat patients with {disease} genetic marker in blood disorders. "
f"List the top 3 with their name, contact details, address, expertise, and available treatments. "
f"Format the response with markdown headings and bullet points."
)
else:
# General query for other conditions
query = (
f"Find hospitals or medical centers in {location}, Pakistan that specialize in "
f"treating {disease}. List the top 3 with their name, contact details, address, "
f"expertise, and available treatments. Format the response with markdown headings and bullet points."
)
logger.info(f"Searching for hospitals treating {disease} in {location}")
# Execute the search using AgentPro
response = agent(query)
# Process and format the response
formatted_response = _format_hospital_response(response, disease, location)
# Cache the result
HOSPITAL_CACHE[cache_key] = (time.time(), formatted_response)
return formatted_response
except Exception as e:
error_msg = f"Error searching for hospitals: {str(e)}"
logger.error(error_msg)
return f"β οΈ {error_msg}\n\nPlease try again later or contact support."
def _format_hospital_response(response: str, disease: str, location: str) -> str:
"""Format the hospital search response for better readability."""
# If response is empty or invalid
if not response or len(response.strip()) < 10:
return f"No specialized hospitals found for {disease} in {location}. Please consult with a general hematologist or oncologist for referrals."
# Add a header and disclaimer
formatted_response = f"""
## Hospitals Specializing in {disease} Treatment in {location}
{response}
---
**Disclaimer:** This information is provided for reference only. Please verify details directly with the hospitals
before making any decisions. Always consult with a qualified healthcare provider for medical advice.
"""
return formatted_response
def get_disease_description(disease: str) -> str:
"""Get a general description of the blood disease or genetic marker."""
descriptions = {
"NPM1": "NPM1 is a genetic mutation commonly found in acute myeloid leukemia (AML). "
"It affects the nucleophosmin protein and is generally associated with a more "
"favorable prognosis compared to some other genetic markers in AML.",
"PML_RARA": "PML-RARA is a fusion gene associated with acute promyelocytic leukemia (APL), "
"a subtype of acute myeloid leukemia. This genetic abnormality is caused by a "
"translocation between chromosomes 15 and 17, and is responsive to targeted therapies.",
"RUNX1_RUNX1T1": "RUNX1-RUNX1T1 (previously known as AML1-ETO) is a fusion gene resulting "
"from a translocation between chromosomes 8 and 21. It is associated with a "
"specific subtype of acute myeloid leukemia (AML) that generally has a favorable prognosis.",
"control": "This indicates a normal or control sample without detected genetic abnormalities "
"associated with leukemia or other blood disorders."
}
return descriptions.get(disease, f"Information about {disease} is not available in the database.")
# --- Configuration ---
# Load Google API Key securely from Streamlit Secrets
try:
api_key = st.secrets["GOOGLE_API_KEY"]
genai.configure(api_key=api_key)
GEMINI_MODEL_NAME = "gemini-1.5-flash" # Or "gemini-pro", etc.
EMBEDDING_MODEL_NAME = "models/text-embedding-004" # Google's text embedding model
except KeyError:
st.error("β Google API Key not found. Please ensure it's in `.streamlit/secrets.toml` as GOOGLE_API_KEY='YourKey'.")
st.stop()
except Exception as e:
st.error(f"β Error configuring Google AI SDK: {e}")
st.stop()
# --- TensorFlow Model Loading ---
@st.cache_resource # Caching is crucial for performance
def load_tf_model(model_path):
"""Loads a TensorFlow/Keras model, handling potential errors."""
if not os.path.exists(model_path):
st.error(f"Model file not found at path: {model_path}")
return None
try:
return tf.keras.models.load_model(model_path)
except Exception as e:
st.error(f"Error loading TensorFlow model from {model_path}: {e}")
return None
# Define model paths
BLOOD_DISEASE_MODEL_PATH = 'blood_cells_model.h5'
CELL_TYPE_MODEL_PATH = 'image_classification_model.h5'
# Load the models
blood_disease_model = load_tf_model(BLOOD_DISEASE_MODEL_PATH)
cell_type_model = load_tf_model(CELL_TYPE_MODEL_PATH)
# Define class names for prediction mapping
# Class names for the "Blood Disease" model (Check this list carefully)
disease_indicator_class_names = ["RUNX1_RUNX1T1", "control", "NPM1", "PML_RARA", "RUNX1_RUNX1T1"]
# Class names for the "Blood Cell Type" model
cell_type_class_names = ["ig", "lymphocyte", "monocyte", "neutrophil", "platelet"]
# --- Gemini Embeddings and FAISS Setup ---
# Paths for saving data
DATA_FILE_PATH = 'data.txt'
FAISS_INDEX_PATH = 'faiss_index.bin'
FAISS_METADATA_PATH = 'faiss_metadata.pkl'
EMBEDDING_DIMENSION = 768 # Default dimension for text-embedding-004, can be reduced
# Initialize embedding model - no need to cache as we'll use the client directly
embedding_model = None # We'll use the genai module directly instead
# Function to generate embeddings using Gemini
def generate_gemini_embedding(text, dimension=None):
"""Generate an embedding for a text using Google's Gemini embedding model."""
try:
# Configure embedding parameters
embed_config = {}
if dimension is not None and dimension > 0:
embed_config["output_dimensionality"] = dimension
# Generate embedding using the embedding model
result = genai.embed_content(
model=EMBEDDING_MODEL_NAME,
content=text,
task_type="RETRIEVAL_QUERY", # For query embedding
**embed_config
)
# Return the embedding values as a numpy array
return np.array(result["embedding"], dtype=np.float32)
except Exception as e:
st.error(f"Error generating embedding: {e}")
return None
# Function to load existing FAISS index if available
def load_faiss_index():
"""Load the FAISS index and metadata if they exist."""
if os.path.exists(FAISS_INDEX_PATH) and os.path.exists(FAISS_METADATA_PATH):
try:
# Load the index
index = faiss.read_index(FAISS_INDEX_PATH)
# Load the metadata
with open(FAISS_METADATA_PATH, 'rb') as f:
metadata = pickle.load(f)
return index, metadata
except Exception as e:
st.warning(f"Failed to load existing FAISS index: {e}. Will create a new one.")
return None, None
return None, None
# Try to load existing index
faiss_index, metadata = load_faiss_index()
# Initialize if doesn't exist
if faiss_index is None:
# Create a new index - configure with the correct dimension
faiss_index = faiss.IndexFlatL2(EMBEDDING_DIMENSION)
metadata = {
'texts': [], # Original texts
'urls': [], # Source URLs
'timestamps': [] # When added
}
# --- Chatbot Context Data ---
def load_knowledge_base():
"""Load the knowledge base from the data.txt file."""
try:
with open(DATA_FILE_PATH, 'r', encoding='utf-8') as file:
return file.read()
except FileNotFoundError:
return "No additional context data found."
data_details = load_knowledge_base()
# System prompt for the chatbot
SYSTEM_PROMPT = f"""You are an AI assistant specialized in providing information about blood cell types and blood diseases. Your purpose is to offer general knowledge and explanations based on established medical information.
You can discuss:
* Different types of blood cells (e.g., lymphocytes, monocytes, neutrophils, platelets, red blood cells) and their functions.
* General information about common blood disorders, conditions, or indicators (e.g., anemia, leukemia, sickle cell disease, or specific genetic markers like NPM1 or PML-RARA mentioned in context).
* Basic concepts related to blood types (e.g., ABO system, Rh factor - but not determine a user's type).
* Definitions of related medical terms.
Use the following specific details if relevant to the user's question and within your scope:
---
{data_details}
---
**IMPORTANT LIMITATIONS: You MUST strictly adhere to the following:**
* **DO NOT provide medical diagnoses.** You cannot tell a user if they have a specific disease.
* **DO NOT interpret personal medical data,** such as lab results or medical images.
* **DO NOT offer medical advice,** treatment recommendations, or suggestions on managing health conditions.
* **DO NOT act as a substitute for a qualified healthcare professional.** Your information is for general knowledge only.
**If a user asks for a diagnosis, medical advice, interpretation of their personal results/images, or asks 'what disease do I have?', you MUST politely refuse.** State clearly that you are an informational AI assistant and cannot provide medical services. **Strongly advise the user to consult with a doctor or qualified healthcare provider** for any personal health concerns, diagnosis, or treatment.
Keep your responses informative, factual, objective, and strictly within the boundaries of providing general educational information. Avoid speculation.
"""
# --- Streamlit App Title ---
st.title("π©Έ AI Chatbot & Blood Classifier")
# --- Chatbot Section ---
st.header("π¬ AI Chat Assistant")
st.caption("Ask questions about blood cells and related diseases (general information only).")
# Initialize chat history in session state
if "messages" not in st.session_state:
st.session_state.messages = []
# Display past chat messages
chat_container = st.container()
with chat_container:
for message in st.session_state.messages:
with st.chat_message(message["role"]):
st.markdown(message["content"])
# Get user input using st.chat_input
if prompt := st.chat_input("Your question..."):
st.session_state.messages.append({"role": "user", "content": prompt})
with chat_container:
with st.chat_message("user"):
st.markdown(prompt)
# Search FAISS index for relevant content if it contains data
if faiss_index.ntotal > 0:
try:
# Generate embedding for the user query using Gemini
query_embedding = generate_gemini_embedding(prompt, dimension=EMBEDDING_DIMENSION)
if query_embedding is not None:
# Reshape to 2D array for faiss search
query_embedding = query_embedding.reshape(1, -1)
# Search the index (get top 3 most similar chunks)
k = min(3, faiss_index.ntotal)
distances, indices = faiss_index.search(query_embedding, k)
# Get the relevant texts
relevant_texts = [metadata['texts'][idx] for idx in indices[0]]
# Add to context (only if there are relevant matches)
if len(relevant_texts) > 0 and distances[0][0] < 20: # Only include if distance is reasonable
context_from_faiss = "\n\nRelevant information from knowledge base:\n" + "\n---\n".join(relevant_texts)
full_prompt = SYSTEM_PROMPT + context_from_faiss + "\n\nUser: " + prompt + "\n\nAssistant:"
else:
full_prompt = SYSTEM_PROMPT + "\n\nUser: " + prompt + "\n\nAssistant:"
else:
full_prompt = SYSTEM_PROMPT + "\n\nUser: " + prompt + "\n\nAssistant:"
except Exception as e:
st.warning(f"Error searching knowledge base: {e}")
full_prompt = SYSTEM_PROMPT + "\n\nUser: " + prompt + "\n\nAssistant:"
else:
full_prompt = SYSTEM_PROMPT + "\n\nUser: " + prompt + "\n\nAssistant:"
try:
with st.spinner("Thinking..."):
model = genai.GenerativeModel(GEMINI_MODEL_NAME)
response = model.generate_content(contents=[full_prompt])
if response.parts:
assistant_response = response.text
elif not response.candidates:
assistant_response = "Response may have been blocked due to safety settings or contains no content."
try:
with chat_container: st.warning(f"Feedback: {response.prompt_feedback}")
except Exception: pass
else:
assistant_response = "Received an unexpected response structure."
with chat_container: st.warning(f"Unexpected response: {response}")
except Exception as e:
st.error(f"β Error generating content: {e}")
assistant_response = f"Sorry, an error occurred: {e}"
st.session_state.messages.append({"role": "assistant", "content": assistant_response})
st.rerun()
# --- Image Classification Section ---
st.divider()
st.header("π¬ Blood Image Classifier")
if blood_disease_model is None or cell_type_model is None:
st.error("One or more classification models failed to load. Cannot proceed.")
else:
col1, col2 = st.columns([1, 2])
with col1:
option = st.selectbox(
"Choose classification mode:",
("Blood Disease", "Blood Cell Type Classification"),
key="classification_type",
help="Blood Disease: Predicts disease indicators (e.g., NPM1). Cell Type: Predicts cell types (e.g., lymphocyte)."
)
# Add location selector for hospital search if Blood Disease is selected
if option == "Blood Disease":
location = st.selectbox(
"Select location for hospital search:",
["Lahore", "Karachi", "Islamabad", "Multan", "Faisalabad", "Peshawar"],
key="location_selector",
help="Select your location to find nearby hospitals that specialize in the detected disease."
)
uploaded_file = st.file_uploader(
"Upload a blood cell image",
type=['png', 'jpg', 'jpeg', 'tiff'],
key="file_uploader"
)
def preprocess_and_predict(image, model, class_names, target_size=(64, 64)):
"""Preprocess image and predict class."""
try:
img_resized = image.resize(target_size)
if img_resized.mode != 'RGB': img_resized = img_resized.convert('RGB')
img_array = np.array(img_resized) / 255.0
img_array = np.expand_dims(img_array, axis=0)
predictions = model.predict(img_array)
pred_index = np.argmax(predictions, axis=1)[0]
if pred_index < len(class_names):
predicted_class = class_names[pred_index]
else:
st.error(f"Pred index {pred_index} out of bounds (len {len(class_names)}).")
return None, None
confidence = np.max(predictions) * 100
return predicted_class, confidence
except Exception as e:
st.error(f"Image processing/prediction error: {e}")
return None, None
with col2:
if uploaded_file is not None:
try:
image = Image.open(uploaded_file)
st.image(image, caption="Uploaded Image", use_column_width=True)
predicted_class = None
confidence = None
with st.spinner("Analyzing image..."):
if option == "Blood Disease":
predicted_class, confidence = preprocess_and_predict(
image, blood_disease_model, disease_indicator_class_names, target_size=(224, 224)
)
elif option == "Blood Cell Type Classification":
predicted_class, confidence = preprocess_and_predict(
image, cell_type_model, cell_type_class_names, target_size=(64, 64)
)
if predicted_class is not None and confidence is not None:
if option == "Blood Disease":
st.success(f"Predicted Disease Indicator: **{predicted_class}**")
# Display disease information
disease_description = get_disease_description(predicted_class)
st.info(f"**About this marker:** {disease_description}")
# Show hospital search section if Blood Disease was detected
location = st.session_state.get("location_selector", "Lahore")
with st.expander(f"Find hospitals for {predicted_class} in {location}", expanded=True):
if st.button("Search for Specialized Hospitals"):
with st.spinner(f"Searching for hospitals that specialize in {predicted_class} in {location}..."):
if hospital_search_available and agent:
try:
response = search_hospitals(agent, predicted_class, location)
st.markdown("### Hospital Recommendations")
st.markdown(response)
except Exception as e:
st.error(f"Error searching for hospitals: {e}")
else:
st.warning("Hospital search is not available because AgentPro could not be initialized.")
else:
st.success(f"Predicted Cell Type: **{predicted_class}**")
st.metric(label="Confidence", value=f"{confidence:.2f}%")
else:
st.warning("Could not make a prediction.")
except Exception as e:
st.error(f"Error handling uploaded image: {e}")
elif option:
placeholder = st.empty()
placeholder.info("Upload an image using the panel on the left.")
# --- Web Scraping and Embedding Section ---
st.divider()
st.header("π Web Content Extractor with FAISS Embedding")
st.caption("Enter a URL to extract its main text content and save it to your knowledge base.")
# Function to scrape data from a single URL
def scrape_website_content(url):
"""Attempts to scrape paragraphs and headings from a given URL."""
try:
# Add scheme if missing
if not url.startswith(('http://', 'https://')):
url = 'https://' + url
# Basic headers
headers = {'User-Agent': 'Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/91.0.4472.124 Safari/537.36'}
response = requests.get(url, headers=headers, timeout=10)
response.raise_for_status() # Check for HTTP errors
soup = BeautifulSoup(response.text, 'html.parser')
# Extract common text elements
paragraphs = soup.find_all('p')
headers = soup.find_all(['h1', 'h2', 'h3'])
# Combine and clean
content_parts = [h.get_text(strip=True) for h in headers if h.get_text(strip=True)]
content_parts.extend([p.get_text(strip=True) for p in paragraphs if p.get_text(strip=True)])
content = '\n\n'.join(content_parts)
if not content: return "Could not find significant text content using p/h1/h2/h3 tags."
return content
except requests.exceptions.RequestException as e: return f"Error fetching URL {url}: {str(e)}"
except Exception as e: return f"Error processing {url}: {str(e)}"
# Function to add scraped content to data.txt and create FAISS embeddings
def save_to_knowledge_base(url, content):
"""Save the content to data.txt and update FAISS embeddings using Gemini."""
# Don't process if content indicates an error
if content.startswith("Error") or content.startswith("Could not find"):
return False, content
# Save to data.txt (append mode)
try:
with open(DATA_FILE_PATH, 'a', encoding='utf-8') as file:
file.write(f"\n\n--- CONTENT FROM: {url} ---\n")
file.write(content)
file.write("\n--- END CONTENT ---\n")
except Exception as e:
return False, f"Error saving to data.txt: {e}"
# Create embeddings and add to FAISS index
try:
# Split content into manageable chunks (max ~500-1000 characters per chunk)
chunks = []
current_chunk = ""
for paragraph in content.split('\n\n'):
if len(current_chunk) + len(paragraph) < 1000: # Rough character limit
if current_chunk: current_chunk += "\n\n"
current_chunk += paragraph
else:
if current_chunk:
chunks.append(current_chunk)
current_chunk = paragraph
if current_chunk: # Add the last chunk
chunks.append(current_chunk)
# Create embeddings for each chunk
embedding_success_count = 0
for chunk in chunks:
# Generate embedding using Gemini
embedding = generate_gemini_embedding(chunk, dimension=EMBEDDING_DIMENSION)
if embedding is not None:
# Add to FAISS index (reshape to 2D array)
embedding = embedding.reshape(1, -1)
faiss_index.add(embedding)
# Add metadata
metadata['texts'].append(chunk)
metadata['urls'].append(url)
metadata['timestamps'].append(time.time())
embedding_success_count += 1
# Save the updated index and metadata
faiss.write_index(faiss_index, FAISS_INDEX_PATH)
with open(FAISS_METADATA_PATH, 'wb') as f:
pickle.dump(metadata, f)
return True, f"Successfully added {embedding_success_count} chunks to knowledge base with Gemini embeddings."
except Exception as e:
return False, f"Error creating embeddings: {e}"
# UI for scraping
user_url = st.text_input("Enter URL:", key="url_input", placeholder="e.g., https://www.example-health-info.com")
col1, col2 = st.columns([1, 1])
with col1:
if st.button("Extract & Save to Knowledge Base", key="scrape_save_button"):
if user_url:
with st.spinner(f"Extracting content from {user_url}..."):
# 1. Scrape content
scraped_content = scrape_website_content(user_url)
st.text_area("Extracted Content:", scraped_content, height=200)
# 2. Save to knowledge base and create embeddings
if not scraped_content.startswith("Error") and not scraped_content.startswith("Could not find"):
with st.spinner("Saving to knowledge base and creating embeddings with Gemini..."):
success, message = save_to_knowledge_base(user_url, scraped_content)
if success:
st.success(message)
else:
st.error(message)
else:
st.warning("Please enter a URL first.")
with col2:
if st.button("View Current Knowledge Base Stats", key="view_kb_stats"):
with st.spinner("Analyzing knowledge base..."):
# Show stats about the knowledge base
if os.path.exists(DATA_FILE_PATH):
with open(DATA_FILE_PATH, 'r', encoding='utf-8') as file:
content = file.read()
total_chars = len(content)
total_lines = content.count('\n') + 1
urls_count = content.count('--- CONTENT FROM:')
st.info(f"""
π **Knowledge Base Stats**
- Total characters: {total_chars:,}
- Total lines: {total_lines:,}
- Sources: {urls_count} URLs
""")
else:
st.info("No knowledge base file found.")
# Show stats about FAISS index
if faiss_index.ntotal > 0:
st.info(f"""
π **FAISS Index Stats**
- Total embeddings: {faiss_index.ntotal:,}
- Unique sources: {len(set(metadata['urls'])):,}
- Embedding dimension: {faiss_index.d}
- Embedding model: {EMBEDDING_MODEL_NAME}
""")
else:
st.info("FAISS index is empty.")
st.caption("Note: Extraction success depends on website structure and permissions. Respect website terms.")
# --- Display Model Summary Section ---
st.divider()
st.header("βοΈ TensorFlow Model Details")
selected_option_for_summary = st.session_state.get("classification_type", "Blood Disease")
with st.expander(f"Show TF Model Summary for '{selected_option_for_summary}'"):
model_to_show = None
if selected_option_for_summary == "Blood Disease": model_to_show = blood_disease_model
elif selected_option_for_summary == "Blood Cell Type Classification": model_to_show = cell_type_model
if model_to_show:
summary_lines = []
model_to_show.summary(print_fn=lambda x: summary_lines.append(x))
st.text('\n'.join(summary_lines))
else: st.warning("Selected classification model could not be loaded/found.")
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