feat: enhance mock data with evidence pointers and MOCK-NCT IDs
Browse files- Add EvidencePointer and TrialEvidencePointer to all criteria for
end-to-end traceability (PRD requirement)
- Use MOCK-NCT prefix on trial IDs to clearly distinguish synthetic data
- Add SourceDocument references for clinic letter, pathology, and labs
- Structure criteria into named variables for readability
Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com>
- app/services/mock_data.py +183 -69
app/services/mock_data.py
CHANGED
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@@ -2,6 +2,10 @@
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Provides realistic sample PatientProfile, TrialCandidates, and EligibilityLedgers
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so the UI is fully demonstrable without real MedGemma/Gemini/MCP calls.
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"""
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from __future__ import annotations
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@@ -13,28 +17,72 @@ from trialpath.models import (
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Demographics,
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Diagnosis,
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EligibilityLedger,
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GapItem,
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OverallAssessment,
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PatientProfile,
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PerformanceStatus,
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Treatment,
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TrialCandidate,
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UnknownField,
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)
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MOCK_PATIENT_PROFILE = PatientProfile(
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patient_id="MOCK-P001",
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demographics=Demographics(age=62, sex="Female"),
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diagnosis=Diagnosis(
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primary_condition="Non-Small Cell Lung Cancer",
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histology="adenocarcinoma",
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stage="IIIB",
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),
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-
performance_status=PerformanceStatus(
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biomarkers=[
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Biomarker(
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],
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treatments=[
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Treatment(drug_name="Carboplatin", line=1),
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],
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)
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MOCK_TRIAL_CANDIDATES = [
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TrialCandidate(
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nct_id="
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title="KEYNOTE-999: Pembrolizumab + Chemo for NSCLC",
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conditions=["NSCLC"],
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phase="Phase 3",
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fingerprint_text="Pembrolizumab combination therapy advanced NSCLC",
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),
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TrialCandidate(
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nct_id="
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title="FLAURA-2: Osimertinib + Chemo in EGFR-mutated NSCLC",
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conditions=["NSCLC", "EGFR mutation"],
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phase="Phase 3",
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fingerprint_text="Osimertinib first-line EGFR mutated advanced NSCLC",
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),
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TrialCandidate(
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nct_id="
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title="CheckMate-817: Nivolumab + Ipilimumab in Advanced NSCLC",
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conditions=["NSCLC"],
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phase="Phase 3",
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),
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]
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),
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),
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),
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-
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),
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],
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gaps=[
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GapItem(
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description="Brain MRI results needed",
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),
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EligibilityLedger(
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patient_id="MOCK-P001",
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nct_id="
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overall_assessment=OverallAssessment.LIKELY_ELIGIBLE,
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criteria=
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CriterionAssessment(
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criterion_id="inc_1",
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type="inclusion",
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text="Confirmed NSCLC with EGFR mutation",
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decision=CriterionDecision.MET,
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),
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CriterionAssessment(
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criterion_id="inc_2",
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type="inclusion",
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text="ECOG 0-1",
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decision=CriterionDecision.MET,
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),
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CriterionAssessment(
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criterion_id="inc_3",
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type="inclusion",
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text="Locally advanced or metastatic",
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decision=CriterionDecision.MET,
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),
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],
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gaps=[],
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),
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EligibilityLedger(
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patient_id="MOCK-P001",
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nct_id="
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overall_assessment=OverallAssessment.LIKELY_INELIGIBLE,
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criteria=
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CriterionAssessment(
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criterion_id="inc_1",
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type="inclusion",
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text="Stage IV NSCLC",
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decision=CriterionDecision.NOT_MET,
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),
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CriterionAssessment(
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criterion_id="inc_2",
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type="inclusion",
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text="No prior immunotherapy",
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decision=CriterionDecision.UNKNOWN,
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),
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],
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gaps=[
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GapItem(
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description="KRAS mutation status unknown",
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Provides realistic sample PatientProfile, TrialCandidates, and EligibilityLedgers
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so the UI is fully demonstrable without real MedGemma/Gemini/MCP calls.
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+
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+
NOTE: NCT IDs use a MOCK-NCT prefix to clearly indicate synthetic data.
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Real trial names are used for demo realism, but the IDs are not real
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ClinicalTrials.gov identifiers.
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"""
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from __future__ import annotations
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Demographics,
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Diagnosis,
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EligibilityLedger,
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+
EvidencePointer,
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GapItem,
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OverallAssessment,
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PatientProfile,
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PerformanceStatus,
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+
SourceDocument,
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Treatment,
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TrialCandidate,
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+
TrialEvidencePointer,
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UnknownField,
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)
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+
# ---------------------------------------------------------------------------
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# Source documents (synthetic)
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# ---------------------------------------------------------------------------
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_CLINIC_LETTER = SourceDocument(
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doc_id="clinic_letter_2026-01.pdf",
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type="clinic_letter",
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meta={"author": "Dr. Mueller", "date": "2026-01-15"},
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)
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_PATHOLOGY_REPORT = SourceDocument(
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doc_id="pathology_2025-11.pdf",
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type="pathology",
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meta={"lab": "Charite Berlin", "date": "2025-11-20"},
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)
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_LAB_RESULTS = SourceDocument(
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doc_id="labs_2026-01.pdf",
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type="lab",
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meta={"date": "2026-01-28"},
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)
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# ---------------------------------------------------------------------------
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# Patient profile
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# ---------------------------------------------------------------------------
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MOCK_PATIENT_PROFILE = PatientProfile(
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patient_id="MOCK-P001",
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source_docs=[_CLINIC_LETTER, _PATHOLOGY_REPORT, _LAB_RESULTS],
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demographics=Demographics(age=62, sex="Female"),
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diagnosis=Diagnosis(
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primary_condition="Non-Small Cell Lung Cancer",
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histology="adenocarcinoma",
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stage="IIIB",
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),
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+
performance_status=PerformanceStatus(
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scale="ECOG",
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value=1,
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evidence=[EvidencePointer(doc_id="clinic_letter_2026-01.pdf", page=1)],
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),
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biomarkers=[
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Biomarker(
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name="EGFR",
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result="Exon 19 deletion",
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evidence=[
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EvidencePointer(doc_id="pathology_2025-11.pdf", page=2, span_id="egfr_exon19")
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],
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),
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+
Biomarker(
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name="ALK",
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result="Negative",
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evidence=[EvidencePointer(doc_id="pathology_2025-11.pdf", page=2, span_id="alk_neg")],
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),
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+
Biomarker(
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name="PD-L1",
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result="45%",
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evidence=[EvidencePointer(doc_id="pathology_2025-11.pdf", page=3, span_id="pdl1_45")],
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),
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],
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treatments=[
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Treatment(drug_name="Carboplatin", line=1),
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],
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)
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+
# ---------------------------------------------------------------------------
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# Trial candidates
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# ---------------------------------------------------------------------------
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MOCK_TRIAL_CANDIDATES = [
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TrialCandidate(
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nct_id="MOCK-NCT-KEYNOTE999",
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title="KEYNOTE-999: Pembrolizumab + Chemo for NSCLC",
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conditions=["NSCLC"],
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phase="Phase 3",
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fingerprint_text="Pembrolizumab combination therapy advanced NSCLC",
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),
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TrialCandidate(
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+
nct_id="MOCK-NCT-FLAURA2",
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title="FLAURA-2: Osimertinib + Chemo in EGFR-mutated NSCLC",
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conditions=["NSCLC", "EGFR mutation"],
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phase="Phase 3",
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fingerprint_text="Osimertinib first-line EGFR mutated advanced NSCLC",
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),
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TrialCandidate(
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+
nct_id="MOCK-NCT-CM817",
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title="CheckMate-817: Nivolumab + Ipilimumab in Advanced NSCLC",
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conditions=["NSCLC"],
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phase="Phase 3",
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),
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]
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+
# ---------------------------------------------------------------------------
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# Eligibility ledgers -- evidence-linked per PRD requirement
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# ---------------------------------------------------------------------------
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+
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# --- KEYNOTE-999: UNCERTAIN (PD-L1 not met at 45% vs >=50%, brain mets unknown) ---
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_KEYNOTE_CRITERIA = [
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+
CriterionAssessment(
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criterion_id="inc_1",
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type="inclusion",
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text="Confirmed NSCLC diagnosis",
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decision=CriterionDecision.MET,
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patient_evidence=[
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EvidencePointer(doc_id="pathology_2025-11.pdf", page=1, span_id="dx_nsclc"),
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],
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trial_evidence=[
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TrialEvidencePointer(field="eligibility_text.inclusion", offset_start=0, offset_end=42),
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],
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),
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+
CriterionAssessment(
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criterion_id="inc_2",
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type="inclusion",
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text="ECOG performance status 0-1",
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decision=CriterionDecision.MET,
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patient_evidence=[
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+
EvidencePointer(doc_id="clinic_letter_2026-01.pdf", page=1, span_id="ecog_1"),
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],
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trial_evidence=[
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+
TrialEvidencePointer(
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field="eligibility_text.inclusion", offset_start=43, offset_end=89
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),
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],
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),
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+
CriterionAssessment(
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criterion_id="inc_3",
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+
type="inclusion",
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text="PD-L1 TPS >= 50%",
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decision=CriterionDecision.NOT_MET,
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patient_evidence=[
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+
EvidencePointer(doc_id="pathology_2025-11.pdf", page=3, span_id="pdl1_45"),
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],
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trial_evidence=[
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+
TrialEvidencePointer(
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field="eligibility_text.inclusion", offset_start=90, offset_end=130
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),
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],
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),
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+
CriterionAssessment(
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criterion_id="exc_1",
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type="exclusion",
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text="No active brain metastases",
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decision=CriterionDecision.UNKNOWN,
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),
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]
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+
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# --- FLAURA-2: LIKELY_ELIGIBLE (EGFR mutation confirmed, stage/ECOG met) ---
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_FLAURA_CRITERIA = [
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+
CriterionAssessment(
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criterion_id="inc_1",
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type="inclusion",
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| 186 |
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text="Confirmed NSCLC with EGFR mutation",
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decision=CriterionDecision.MET,
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| 188 |
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patient_evidence=[
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EvidencePointer(doc_id="pathology_2025-11.pdf", page=2, span_id="egfr_exon19"),
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],
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trial_evidence=[
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TrialEvidencePointer(field="eligibility_text.inclusion", offset_start=0, offset_end=54),
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],
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),
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+
CriterionAssessment(
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| 196 |
+
criterion_id="inc_2",
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| 197 |
+
type="inclusion",
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| 198 |
+
text="ECOG 0-1",
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+
decision=CriterionDecision.MET,
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+
patient_evidence=[
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+
EvidencePointer(doc_id="clinic_letter_2026-01.pdf", page=1, span_id="ecog_1"),
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+
],
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+
trial_evidence=[
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+
TrialEvidencePointer(
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field="eligibility_text.inclusion", offset_start=55, offset_end=78
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),
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],
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),
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| 209 |
+
CriterionAssessment(
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criterion_id="inc_3",
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type="inclusion",
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text="Locally advanced or metastatic",
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decision=CriterionDecision.MET,
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patient_evidence=[
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EvidencePointer(doc_id="clinic_letter_2026-01.pdf", page=1, span_id="stage_iiib"),
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],
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trial_evidence=[
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+
TrialEvidencePointer(
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field="eligibility_text.inclusion", offset_start=79, offset_end=125
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),
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],
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),
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]
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+
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# --- CheckMate-817: LIKELY_INELIGIBLE (requires Stage IV, patient is IIIB) ---
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_CM817_CRITERIA = [
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+
CriterionAssessment(
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criterion_id="inc_1",
|
| 229 |
+
type="inclusion",
|
| 230 |
+
text="Stage IV NSCLC",
|
| 231 |
+
decision=CriterionDecision.NOT_MET,
|
| 232 |
+
patient_evidence=[
|
| 233 |
+
EvidencePointer(doc_id="clinic_letter_2026-01.pdf", page=1, span_id="stage_iiib"),
|
| 234 |
+
],
|
| 235 |
+
trial_evidence=[
|
| 236 |
+
TrialEvidencePointer(field="eligibility_text.inclusion", offset_start=0, offset_end=35),
|
| 237 |
+
],
|
| 238 |
+
),
|
| 239 |
+
CriterionAssessment(
|
| 240 |
+
criterion_id="inc_2",
|
| 241 |
+
type="inclusion",
|
| 242 |
+
text="No prior immunotherapy",
|
| 243 |
+
decision=CriterionDecision.UNKNOWN,
|
| 244 |
+
),
|
| 245 |
+
]
|
| 246 |
+
|
| 247 |
+
MOCK_ELIGIBILITY_LEDGERS = [
|
| 248 |
+
EligibilityLedger(
|
| 249 |
+
patient_id="MOCK-P001",
|
| 250 |
+
nct_id="MOCK-NCT-KEYNOTE999",
|
| 251 |
+
overall_assessment=OverallAssessment.UNCERTAIN,
|
| 252 |
+
criteria=_KEYNOTE_CRITERIA,
|
| 253 |
gaps=[
|
| 254 |
GapItem(
|
| 255 |
description="Brain MRI results needed",
|
|
|
|
| 260 |
),
|
| 261 |
EligibilityLedger(
|
| 262 |
patient_id="MOCK-P001",
|
| 263 |
+
nct_id="MOCK-NCT-FLAURA2",
|
| 264 |
overall_assessment=OverallAssessment.LIKELY_ELIGIBLE,
|
| 265 |
+
criteria=_FLAURA_CRITERIA,
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 266 |
gaps=[],
|
| 267 |
),
|
| 268 |
EligibilityLedger(
|
| 269 |
patient_id="MOCK-P001",
|
| 270 |
+
nct_id="MOCK-NCT-CM817",
|
| 271 |
overall_assessment=OverallAssessment.LIKELY_INELIGIBLE,
|
| 272 |
+
criteria=_CM817_CRITERIA,
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 273 |
gaps=[
|
| 274 |
GapItem(
|
| 275 |
description="KRAS mutation status unknown",
|