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| """ | |
| Prompt templates for ActiveMedAgent. | |
| Three semantically equivalent but lexically different variants (A/B/C) | |
| for prompt sensitivity analysis. | |
| Each prompt has: | |
| - system_prompt: Sets the agent's role and reasoning format | |
| - acquisition_prompt: Asks the agent to decide what to request next | |
| - diagnosis_prompt: Asks the agent to commit to a ranked differential | |
| """ | |
| # ============================================================ | |
| # Channel description formatters | |
| # ============================================================ | |
| def format_available_channels(channels: dict, already_acquired: list[str]) -> str: | |
| """Format the list of requestable channels for the prompt.""" | |
| lines = [] | |
| sortable = [] | |
| for name, info in channels.items(): | |
| if info.get("always_given"): | |
| continue | |
| if name in already_acquired: | |
| continue | |
| sortable.append((info.get("order", 999), info.get("cost", 0.0), name, info)) | |
| for _, _, name, info in sorted(sortable): | |
| cost = float(info.get("cost", 0.0)) | |
| tier = info.get("tier", "unknown") | |
| lines.append( | |
| f" - [{name}]: {info['description']} " | |
| f"(tier: {tier}, cost: ${cost:,.0f})" | |
| ) | |
| if not lines: | |
| return " (No additional information available to request.)" | |
| return "\n".join(lines) | |
| def format_acquired_info(acquired_data: dict) -> str: | |
| """Format all previously acquired information for context.""" | |
| if not acquired_data: | |
| return "(No additional information acquired yet.)" | |
| parts = [] | |
| for channel_name, content in acquired_data.items(): | |
| if content["type"] == "text": | |
| parts.append(f"[{channel_name}]: {content['value']}") | |
| elif content["type"] == "image": | |
| parts.append(f"[{channel_name}]: (image provided)") | |
| return "\n".join(parts) | |
| # ============================================================ | |
| # Prompt Variant A β Clinical Framing | |
| # ============================================================ | |
| VARIANT_A = { | |
| "name": "clinical", | |
| "system_prompt": """You are an experienced physician performing a diagnostic evaluation. \ | |
| You will be shown a medical image and possibly additional clinical information. \ | |
| Your goal is to arrive at the most accurate diagnosis by strategically requesting \ | |
| the most informative additional data. | |
| You reason through cases using a structured clinical approach: | |
| 1. OBSERVATION: Describe what you see in the available image(s) and data. | |
| 2. DIFFERENTIAL: List your top 3-5 candidate diagnoses ranked by likelihood, with confidence estimates (0-1). | |
| 3. UNCERTAINTY: Identify specifically what you are uncertain about β which diagnoses cannot be distinguished with current information and WHY. | |
| 4. ACTION: You MUST request one additional piece of information. Choose the one that would best disambiguate your top differential diagnoses. | |
| CRITICAL: You must ALWAYS use your remaining budget to request information. \ | |
| Do NOT commit early β additional information almost always improves diagnostic accuracy. \ | |
| Always respond in this exact structured format.""", | |
| "acquisition_prompt": """You have {remaining_budget} request(s) remaining. You MUST use them. | |
| Available information you can request: | |
| {available_channels} | |
| Previously acquired information: | |
| {acquired_info} | |
| Think carefully: which available channel would MOST help distinguish between your top diagnoses? | |
| Respond in EXACTLY this format: | |
| OBSERVATION: [What you observe from all currently available information] | |
| DIFFERENTIAL: [Ranked list β format each as "N. DiagnosisName (confidence: X.XX)"] | |
| UNCERTAINTY: [Which two diagnoses are hardest to tell apart, and what specific information would resolve it] | |
| ACTION: REQUEST [channel_name] | |
| IMPORTANT: Replace [channel_name] with exactly one of the available channel names listed above. \ | |
| You MUST request a channel β do not skip or commit early.""", | |
| "diagnosis_prompt": """You strategically gathered the most relevant clinical information. \ | |
| Now provide your final diagnosis. Focus on the evidence you acquired β it was selected \ | |
| specifically to resolve diagnostic uncertainty. | |
| Information you gathered: | |
| {acquired_info} | |
| Candidate diagnoses to rank: | |
| {candidates} | |
| Respond in the structured format: | |
| OBSERVATION: [Synthesis of the key findings from your acquired information] | |
| DIFFERENTIAL: [Ranked candidates β format each as "N. DiagnosisName (confidence: X.XX)"] | |
| REASONING: [Key evidence from your acquired data supporting your top diagnosis and ruling out alternatives]""", | |
| } | |
| # ============================================================ | |
| # Prompt Variant B β Information-Theoretic Framing | |
| # ============================================================ | |
| VARIANT_B = { | |
| "name": "information_theoretic", | |
| "system_prompt": """You are an AI diagnostic system analyzing medical data under \ | |
| conditions of incomplete information. You process available evidence and estimate which \ | |
| additional data sources would most reduce your diagnostic uncertainty. | |
| Your reasoning follows a structured protocol: | |
| 1. EVIDENCE: Catalog the findings from all available inputs. | |
| 2. HYPOTHESES: Rank candidate diagnoses by posterior probability (0-1, must sum to β€1). | |
| 3. INFORMATION GAP: Identify the highest-uncertainty region of your hypothesis space. | |
| 4. ACQUISITION: Select the data source with highest expected information gain, or finalize. | |
| Always respond in this exact structured format. Be precise with probabilities.""", | |
| "acquisition_prompt": """Analyze your current diagnostic uncertainty and determine the \ | |
| optimal next data acquisition. You have {remaining_budget} acquisition(s) remaining. | |
| Requestable data sources: | |
| {available_channels} | |
| Previously acquired data: | |
| {acquired_info} | |
| Respond in the structured format: | |
| EVIDENCE: [Findings extracted from all currently available data] | |
| HYPOTHESES: [Ranked list β format each as "N. DiagnosisName (probability: X.XX)"] | |
| INFORMATION GAP: [Which distinction between top hypotheses cannot be resolved with current data, and why] | |
| ACQUISITION: REQUEST [channel_name] β [expected information gain explanation] | |
| If your top hypothesis probability exceeds 0.8 and is well-separated from alternatives: | |
| ACQUISITION: FINALIZE""", | |
| "diagnosis_prompt": """All data acquisition is complete. Produce your final ranked \ | |
| hypothesis set. | |
| Accumulated data: | |
| {acquired_info} | |
| Candidate diagnoses to rank: | |
| {candidates} | |
| Respond in the structured format: | |
| EVIDENCE: [Complete synthesis of all acquired data] | |
| HYPOTHESES: [Final ranked candidates β format each as "N. DiagnosisName (probability: X.XX)"] | |
| JUSTIFICATION: [Evidence chain supporting top hypothesis; contradicting evidence for alternatives]""", | |
| } | |
| # ============================================================ | |
| # Prompt Variant C β Neutral/Minimal Framing | |
| # ============================================================ | |
| VARIANT_C = { | |
| "name": "neutral", | |
| "system_prompt": """You are assisting with medical image analysis. Given a medical image \ | |
| and possibly additional information, identify the most likely diagnosis from a set of candidates. | |
| You may request additional information before making your final decision. Structure your \ | |
| response as follows: | |
| 1. FINDINGS: What you observe. | |
| 2. RANKING: Candidate diagnoses ranked with confidence scores (0-1). | |
| 3. GAPS: What you don't know that would help. | |
| 4. DECISION: Request more info or commit.""", | |
| "acquisition_prompt": """You may request one more piece of information. \ | |
| {remaining_budget} request(s) left. | |
| Options: | |
| {available_channels} | |
| Information so far: | |
| {acquired_info} | |
| Respond: | |
| FINDINGS: [Current observations] | |
| RANKING: [Format: "N. DiagnosisName (confidence: X.XX)"] | |
| GAPS: [What's missing] | |
| DECISION: REQUEST [channel_name] β [reason] | |
| Or if ready: | |
| DECISION: COMMIT""", | |
| "diagnosis_prompt": """Provide your final diagnosis ranking. | |
| All information: | |
| {acquired_info} | |
| Candidates: | |
| {candidates} | |
| Respond: | |
| FINDINGS: [Summary] | |
| RANKING: [Format: "N. DiagnosisName (confidence: X.XX)"] | |
| REASONING: [Brief justification]""", | |
| } | |
| # ============================================================ | |
| # Variant Registry | |
| # ============================================================ | |
| PROMPT_VARIANTS = { | |
| "A": VARIANT_A, | |
| "B": VARIANT_B, | |
| "C": VARIANT_C, | |
| } | |
| def get_prompt_variant(variant_id: str) -> dict: | |
| """Retrieve a prompt variant by ID.""" | |
| if variant_id not in PROMPT_VARIANTS: | |
| raise ValueError(f"Unknown prompt variant: {variant_id}. Choose from {list(PROMPT_VARIANTS.keys())}") | |
| return PROMPT_VARIANTS[variant_id] | |