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"""Perform model calibration in CV on different algorithms and log to mlflow.

Nests runs for different algos under parent run and logs the following
artifacts as well as metrics and parameters:
1. Calibration curves for each child algo run (calibration in CV and calibration on
   holdout test after applying isotonic and sigmoid calibration)
2. Calibration curve under parent run to compare all algos in CV and post calibration
3. Cumulative gains curve
4. Lift curve
5. Probability distributions with KDE (CV)
"""
import matplotlib.pyplot as plt
import matplotlib.lines as mlines
from lenusml import splits, plots
import numpy as np
import os
import pandas as pd

from sklearn.model_selection import cross_val_predict, cross_validate
from sklearn.calibration import calibration_curve, CalibratedClassifierCV

from sklearn.linear_model import LogisticRegression
from imblearn.ensemble import BalancedRandomForestClassifier, BalancedBaggingClassifier
from sklearn.ensemble import RandomForestClassifier
import xgboost as xgb
import lightgbm as lgb
from interpret.glassbox import ExplainableBoostingClassifier

import mlflow
from mlflow.utils.mlflow_tags import MLFLOW_PARENT_RUN_ID


data_dir = '../data/models/model1/'
cohort_info_dir = '../data/cohort_info/'
output_dir = '../data/models/model1/output'

# Load CV folds and train data
fold_patients = np.load(os.path.join(cohort_info_dir, 'fold_patients.npy'),
                        allow_pickle=True)
train_data = pd.read_pickle(os.path.join(data_dir, 'train_data_cv.pkl'))
test_data = pd.read_pickle(os.path.join(data_dir, 'test_data.pkl'))
# Cross check fold patients with train data
cross_validation_fold_indices = splits.custom_cv_fold_indices(fold_patients=fold_patients,
                                                              train_data=train_data,
                                                              id_column='StudyId')

mlflow.set_tracking_uri("sqlite:///mlruns.sqlite")
mlflow.set_experiment('model_drop2')

# Set CV scoring strategies and any model parameters
scoring = ['f1', 'balanced_accuracy', 'accuracy', 'precision', 'recall', 'roc_auc',
           'average_precision', 'neg_brier_score']


def plot_calibration_curves(calibration_curves, savefig=True, output_dir=None,
                            figname=None, figsize=(8, 7)):
    fig, ax = plt.subplots(figsize=figsize)
    # reference line, legends, and axis labels
    line = mlines.Line2D([0, 1], [0, 1], color='black')
    transform = ax.transAxes
    line.set_transform(transform)
    ax.add_line(line)
    fig.suptitle('Calibration plot')
    ax.set_xlabel('Predicted probability')
    ax.set_ylabel('True probability in each bin')
    color = iter(plt.cm.rainbow(np.linspace(0, 1, len(calibration_curves))))
    for cal_curve in calibration_curves:
        c = next(color)
        plt.plot(cal_curve[0][1], cal_curve[0][0], marker='o', c=c, linewidth=1,
                 label=cal_curve[1])
    plt.xlim(0, 1)
    plt.ylim(0, 1)
    plt.legend(frameon=False, bbox_to_anchor=(1, 1), loc="upper left")
    plt.tight_layout()
    if savefig:
        plt.savefig(os.path.join(output_dir, figname))


def plot_calibration_curves_algo(calibration_curves, savefig=True, output_dir=None,
                                 figname=None, figsize=(8, 7)):
    fig, ax = plt.subplots(figsize=figsize)
    # reference line, legends, and axis labels
    line = mlines.Line2D([0, 1], [0, 1], color='black')
    transform = ax.transAxes
    line.set_transform(transform)
    ax.add_line(line)
    fig.suptitle('Calibration plot')
    ax.set_xlabel('Predicted probability')
    ax.set_ylabel('True probability in each bin')
    for cal_curve in calibration_curves:
        plt.plot(cal_curve[0][1], cal_curve[0][0], marker='o', linewidth=1,
                 label=cal_curve[1])
    plt.xlim(0, 1)
    plt.ylim(0, 1)
    plt.legend(frameon=False)
    plt.tight_layout()
    if savefig:
        plt.savefig(os.path.join(output_dir, figname))


# Create list of model features
cols_to_drop = ['StudyId', 'IsExac']

# Get the features list from the preferred model
with open('./mlruns/2/7ebf60a5d17f49d9a79e41dd72dda858/artifacts/features.txt') as f:
    features_list = f.read().splitlines()

# Separate features from target
features_train = train_data[features_list].astype('float')
target_train = train_data.IsExac.astype('float')
features_test = test_data[features_list].astype('float')
target_test = test_data.IsExac.astype('float')

artifact_dir = './tmp'
# Create the artifacts directory if it doesn't exist
os.makedirs(artifact_dir, exist_ok=True)
# Remove any existing directory contents to not mix files between different runs
for f in os.listdir(artifact_dir):
    os.remove(os.path.join(artifact_dir, f))

scale_pos_weight = target_train.value_counts()[0] / target_train.value_counts()[1]

# Create list of algos to try
models = []
models.append((LogisticRegression(random_state=0, max_iter=200), 'LR'))
models.append((LogisticRegression(random_state=0, class_weight='balanced', max_iter=200),
               'LR_CW_balanced'))
models.append((lgb.LGBMClassifier(random_state=0), 'LGBM'))
models.append((BalancedBaggingClassifier(random_state=0),
               'Balanced_bagging'))
models.append((BalancedRandomForestClassifier(random_state=0), 'Balanced_RF'))
models.append((xgb.XGBClassifier(random_state=0, use_label_encoder=False,
               eval_metric='logloss'), 'XGB'))
models.append((xgb.XGBClassifier(random_state=0, use_label_encoder=False,
               eval_metric='logloss', scale_pos_weight=scale_pos_weight), 'XGB_SPW'))
models.append((ExplainableBoostingClassifier(random_state=0), 'EBM'))
models.append((RandomForestClassifier(random_state=0), 'RF'))
models.append((RandomForestClassifier(random_state=0, class_weight='balanced'),
               'RF_CW_balanced'))

calibration_curves_cv = []
calibration_curves_sigmoid = []
calibration_curves_isotonic = []

cal_curve_strategy = 'uniform'

with mlflow.start_run(run_name='sklearn_calibration_in_cv_uniform_bins'):
    # Perform K-fold cross validation
    runid = mlflow.active_run().info.run_id
    for model in models:
        with mlflow.start_run(run_name=model[1], nested=True,
                              tags={MLFLOW_PARENT_RUN_ID: runid}):
            # Remove any existing directory contents to not mix files between different
            # runs
            for f in os.listdir(artifact_dir):
                os.remove(os.path.join(artifact_dir, f))

            calibration_curves_algo = []
            crossval = cross_validate(model[0], features_train, target_train,
                                      cv=cross_validation_fold_indices,
                                      return_estimator=True, scoring=scoring,
                                      error_score='raise')
            probabilities_cv = cross_val_predict(model[0], features_train, target_train,
                                                 cv=cross_validation_fold_indices,
                                                 method='predict_proba')[:, 1]

            model_scores = pd.DataFrame({'model_score': probabilities_cv,
                                         'true_label': target_train})
            model_scores = model_scores.sort_values(by='model_score', ascending=False)

            # Extract calibration curve
            calibration_curves_cv.append((calibration_curve(target_train,
                                          probabilities_cv, n_bins=10,
                                          strategy=cal_curve_strategy), model[1]))

            # Log metrics averaged across folds
            for score in scoring:
                mlflow.log_metric(score, np.mean(crossval['test_' + score]))

            # Log model parameters
            params = model[0].get_params()
            for param in params:
                mlflow.log_param(param, params[param])

            # Calibrate model in CV
            calibrated_sigmoid = CalibratedClassifierCV(model[0], method='sigmoid',
                                                        cv=cross_validation_fold_indices)
            calibrated_sigmoid.fit(features_train, target_train)
            probabilities_sigmoid = calibrated_sigmoid.predict_proba(features_test)[:, 1]

            calibrated_isotonic = CalibratedClassifierCV(model[0], method='isotonic',
                                                         cv=cross_validation_fold_indices)
            calibrated_isotonic.fit(features_train, target_train)
            probabilities_isotonic = calibrated_isotonic.predict_proba(
                features_test)[:, 1]

            # Extract calibration curve
            calibration_curves_sigmoid.append((calibration_curve(target_test,
                                               probabilities_sigmoid, n_bins=10,
                                               strategy=cal_curve_strategy),
                                               model[1] + ' sigmoid'))
            calibration_curves_isotonic.append((calibration_curve(target_test,
                                                probabilities_isotonic, n_bins=10,
                                                strategy=cal_curve_strategy),
                                                model[1] + ' isotonic'))
            calibration_curves_algo.append((calibration_curve(target_train,
                                            probabilities_cv, n_bins=10,
                                            strategy=cal_curve_strategy),
                                            model[1] + ' uncalibrated'))
            calibration_curves_algo.append((calibration_curve(target_test,
                                            probabilities_sigmoid, n_bins=10,
                                            strategy=cal_curve_strategy),
                                            model[1] + ' sigmoid'))
            calibration_curves_algo.append((calibration_curve(target_test,
                                            probabilities_isotonic, n_bins=10,
                                            strategy=cal_curve_strategy),
                                            model[1] + ' isotonic'))

            # Plot cumulative gains curves
            plots.plot_cumulative_gains_curve(scores=model_scores, savefig=True,
                                              output_dir=artifact_dir,
                                              figname='cumulative_gains_curve.png')
            # Plot lift curves
            plots.plot_lift_curve(scores=model_scores, savefig=True,
                                  output_dir=artifact_dir, figname='lift_curve.png')

            # Plot distribution of model scores (histogram plus KDE)
            plots.plot_score_distribution(scores=model_scores,
                                          postive_class_name='Exac',
                                          negative_class_name='No exac', savefig=True,
                                          output_dir=artifact_dir,
                                          figname='model_score_distribution.png')

            # Plot calibration curves for each algo
            plot_calibration_curves_algo(calibration_curves=calibration_curves_algo,
                                         savefig=True, output_dir=artifact_dir,
                                         figname='calibration_curves.png',
                                         figsize=(8, 7))

            # Log artifacts under child runs
            mlflow.log_artifacts(artifact_dir)
            mlflow.end_run()

# Log artifacts under parent run
for f in os.listdir(artifact_dir):
    os.remove(os.path.join(artifact_dir, f))

plot_calibration_curves(calibration_curves=calibration_curves_cv, savefig=True,
                        output_dir=artifact_dir,
                        figname='calibration_curves_cv.png', figsize=(15, 10))
plot_calibration_curves(calibration_curves=calibration_curves_sigmoid, savefig=True,
                        output_dir=artifact_dir,
                        figname='calibration_curves_sigmoid.png', figsize=(15, 10))
plot_calibration_curves(calibration_curves=calibration_curves_isotonic, savefig=True,
                        output_dir=artifact_dir,
                        figname='calibration_curves_isotonic.png', figsize=(15, 10))

with mlflow.start_run(run_id=runid):
    mlflow.log_artifacts(artifact_dir)
    mlflow.end_run()