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---
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language:
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- en
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metrics:
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- accuracy
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- AUC ROC
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- precision
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- recall
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tags:
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- biology
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- chemistry
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- therapeutic science
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- drug design
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- drug development
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- therapeutics
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library_name: tdc
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license: bsd-2-clause
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---
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The TDC Transformers APi is still under development. You may download PINNACLE pre-trained weights and hyperparameters from the files included.
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## Model description
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We introduce PINNACLE, a flexible geometric deep-learning approach that is trained on contextualized protein interaction networks to generate context-PINNACLE protein representations. Leveraging a human multi-organ single-cell transcriptomic atlas, PINNACLE provides 394,760 protein representations split across 156 cell type contexts from 24 tissues and organs.
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To load the pre-trained model, use the Files and Versions tab files.
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## References
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* Dataset entry in Therapeutics Data Commons, https://tdcommons.ai/multi_pred_tasks/scdti/
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* Li, Michelle, et al. “Contextualizing Protein Representations Using Deep Learning on Protein Networks and Single-Cell Data” bioRxiv (2023)
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