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license: apache-2.0
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---
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license: apache-2.0
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---
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## 🚀 Introduction (ProtSSN)
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Fusion of protein **sequence and structural** information, using **denoising** pre-training network for **protein engineering** (**zero-shot**).
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## 📑 Github
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https://github.com/tyang816/ProtSSN
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## 🙌 Citation
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Please cite our work if you have used our code or data for **dry experiment testing/wet experiment directed evolution**. We are pleased to see improvements in the subsequent work.
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```
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@article{tan2023protssn,
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title={Semantical and Topological Protein Encoding Toward Enhanced Bioactivity and Thermostability},
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author={Tan, Yang and Zhou, Bingxin and Zheng, Lirong and Fan, Guisheng and Hong, Liang},
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journal={bioRxiv},
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pages={2023--12},
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year={2023},
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publisher={Cold Spring Harbor Laboratory}
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}
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```
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