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Pinal is an advanced protein design framework that translates human design intent into novel protein sequences. It utilizes a two-stage process: first generating protein structures from language instructions, then designing sequences based on those structures. With a substantial parameter count of 16 billion and trained on a diverse dataset comprising 1.7 billion protein-text pairs, Pinal demonstrates marked improvements in both performance and generalization capabilities for novel protein structures.
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Pinal is an advanced protein design framework that translates human design intent into novel protein sequences. It utilizes a two-stage process: first generating protein structures from language instructions, then designing sequences based on those structures. With a substantial parameter count of 16 billion and trained on a diverse dataset comprising 1.7 billion protein-text pairs, Pinal demonstrates marked improvements in both performance and generalization capabilities for novel protein structures.
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For more information, please refer to our [preprint](https://www.biorxiv.org/content/10.1101/2024.08.01.606258).
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