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@@ -9,107 +9,131 @@ tags:
9
  - loss:MultipleNegativesRankingLoss
10
  base_model: google/embeddinggemma-300m
11
  widget:
12
- - source_sentence: 'How can training influence nurses'' awareness of medication errors?
13
-
14
- '
15
  sentences:
16
- - Treatment with obeticholic acid resulted in significant reductions in serum alanine
17
- aminotransferase (ALT) and aspartate aminotransferase (AST) concentrations over
18
- the first 36 weeks of treatment, and these reductions were sustained for the duration
19
- of treatment. However, serum alkaline phosphatase concentrations increased with
20
- obeticholic acid treatment, although γ-glutamyl transpeptidase concentrations
21
- (another indicator of cholestasis) decreased. These changes in liver enzyme concentrations
22
- reversed after obeticholic acid was stopped, and at 24 weeks after treatment discontinuation,
23
- there were no significant differences between the obeticholic acid group and the
24
- placebo group.
25
- - Training can increase nurses' awareness of medication errors by providing them
26
- with the knowledge and skills necessary to identify and prevent errors. Through
27
- training, nurses can learn about medication safety protocols, proper medication
28
- administration techniques, and the importance of error reporting. This increased
29
- awareness can help nurses recognize potential errors and take appropriate actions
30
- to prevent harm to patients.
31
- - ML171, also known as 2-acetylphenothiazine, has been identified as a specific
32
- NOX1 oxidase inhibitor at nanomolar concentrations. It shows minimal activity
33
- on other cellular ROS-producing sources, including xanthine oxidase and other
34
- NADPH oxidases. ML171 targets the NOX1 catalytic subunit without affecting its
35
- cytosolic regulators, such as the NOXO1, NOXA1, or RAC1 subunits. It effectively
36
- blocks NOX1 oxidase-dependent ROS-mediated formation of extracellular matrix-degrading
37
- invadopodia in colon cancer cells.
38
- - source_sentence: 'What are the potential adverse effects of benzodiazepines?
39
-
40
- '
 
 
 
 
41
  sentences:
42
- - The peak concentration (C max ) of perindopril refers to the highest concentration
43
- of the drug in the plasma. The time to reach the C max (T max ) indicates how
44
- long it takes for the drug to reach its maximum concentration. These parameters
45
- are important in understanding the absorption and distribution of perindopril
46
- in the body.
47
- - 'The Multi-drug Therapy (MDT) for leprosy uses a combination of three drugs: Rifampicine,
48
- Dapsone, and Clofazimine.'
49
- - Benzodiazepines can induce adverse effects such as oversedation, cognitive impairment,
50
- motor impairment, and withdrawal. These effects may be associated with the elimination
51
- half-life of the compounds, where long-term use of compounds with a short elimination
52
- rate may induce withdrawal syndromes, and accumulation-related effects of a long
53
- elimination rate may include oversedation, cognitive dysfunction, and motor impairment.
54
- - source_sentence: 'What is the role of resveratrol as an additive to paclitaxel in
55
- drug coatings?
56
-
57
- '
 
 
 
58
  sentences:
59
- - Traditional opioids are effective against severe pain but have problematic side
60
- effects and limited efficacy against neuropathic pain. In contrast, IBNtxA, a
61
- novel opioid analgesic, is a potent analgesic against thermal, inflammatory, and
62
- neuropathic pain without causing side effects such as respiratory depression,
63
- physical dependence, or reward behavior.
64
- - TXA is contraindicated in patients with severe kidney dysfunction due to the risk
65
- of accumulation. However, dosages do not need to be modified in patients with
66
- impaired liver function and elderly patients with no kidney dysfunction.
67
- - Resveratrol is an additive to paclitaxel in drug coatings that helps modulate
68
- adherence and release of the drug. It has been found to reduce drug loss during
69
- passage through the hemostatic valve and sheath and during floating in blood.
70
- Resveratrol has lower water-solubility compared to other additives, which may
71
- contribute to its diminished drug loss. Previous experiments and published data
72
- suggest that resveratrol is a useful coating additive in drug delivery systems.
73
- - source_sentence: What are the most common nonhematologic toxicities associated with
74
- OXi4503 infusion?
 
 
 
 
 
 
75
  sentences:
76
- - The concentration of tetracycline taken up by mineralizing cell systems, such
77
- as enamel, bone, or dentin, may be influenced by the distinctive protein produced
78
- by these systems and the cofactors required, as well as the availability of calcium
79
- or other ions for chelating tetracycline. The amount of tetracycline available
80
- and the fluorescence observed in tissues may vary depending on the particular
81
- hard tissue system and the specific mineralizing cell system. However, the absence
82
- of fluorescence should not be taken as an assured absence of tetracycline, as
83
- fluorescence alone is not sufficient to establish a quantitative assay for tetracycline.
84
- - The most common nonhematologic toxicities associated with OXi4503 infusion are
85
- tumor pain, nausea and/or vomiting, cardiac symptoms (hypertension, tachycardia,
86
- and QTc prolongation), and neurologic symptoms.
87
- - The recommended categories for stocking antidotes in hospitals are divided into
88
- two. Firstly, 12 antidotes should be available in the hospital emergency department
89
- for immediate use upon poisoned patient arrival. Secondly, nine antidotes should
90
- be available in the pharmacy to be administered within an hour of when the antidote
91
- is deemed necessary. Three additional antidotes are recommended to be stocked
92
- by the hospital, although they are not usually needed within the first hour of
93
- treatment.
94
- - source_sentence: What is the purpose of dabigatran and why was it prescribed to
95
- the 71-year-old female?
 
 
 
 
 
96
  sentences:
97
- - Melatonin agonists may have side effects such as nausea, headache, elevated liver
98
- enzyme levels, rebound insomnia, withdrawal symptoms, and addiction. Contraindications
99
- include liver failure, renal failure, alcohol addiction, and high lipid levels.
100
- - G-protein coupled receptors, like OXTR and MOR, can form homo- or hetero-dimers,
101
- which means they can associate with another molecule of the same receptor or with
102
- receptors from other families. This physical association has been shown to modulate
103
- receptor binding and function. For example, in MOR-alpha2A-adrenergic receptor
104
- dimers, the activation of MOR by morphine inhibits the adjacent alpha2A-receptor
105
- by blocking its ability to activate the G-proteins, even in the presence of noradrenaline.
106
- - Dabigatran is prescribed for stroke prevention in patients with atrial fibrillation.
107
- Atrial fibrillation increases the risk of blood clots forming in the heart, which
108
- can then travel to the brain and cause a stroke. Dabigatran is an anticoagulant
109
- that helps prevent the formation of blood clots, reducing the risk of stroke in
110
- patients with atrial fibrillation.
 
 
 
 
 
111
  pipeline_tag: sentence-similarity
112
  library_name: sentence-transformers
 
 
113
  ---
114
 
115
  # SentenceTransformer based on google/embeddinggemma-300m
 
9
  - loss:MultipleNegativesRankingLoss
10
  base_model: google/embeddinggemma-300m
11
  widget:
12
+ - source_sentence: |
13
+ How can training influence nurses' awareness of medication errors?
 
14
  sentences:
15
+ - >-
16
+ Treatment with obeticholic acid resulted in significant reductions in serum
17
+ alanine aminotransferase (ALT) and aspartate aminotransferase (AST)
18
+ concentrations over the first 36 weeks of treatment, and these reductions
19
+ were sustained for the duration of treatment. However, serum alkaline
20
+ phosphatase concentrations increased with obeticholic acid treatment,
21
+ although γ-glutamyl transpeptidase concentrations (another indicator of
22
+ cholestasis) decreased. These changes in liver enzyme concentrations
23
+ reversed after obeticholic acid was stopped, and at 24 weeks after treatment
24
+ discontinuation, there were no significant differences between the
25
+ obeticholic acid group and the placebo group.
26
+ - >-
27
+ Training can increase nurses' awareness of medication errors by providing
28
+ them with the knowledge and skills necessary to identify and prevent errors.
29
+ Through training, nurses can learn about medication safety protocols, proper
30
+ medication administration techniques, and the importance of error reporting.
31
+ This increased awareness can help nurses recognize potential errors and take
32
+ appropriate actions to prevent harm to patients.
33
+ - >-
34
+ ML171, also known as 2-acetylphenothiazine, has been identified as a
35
+ specific NOX1 oxidase inhibitor at nanomolar concentrations. It shows
36
+ minimal activity on other cellular ROS-producing sources, including xanthine
37
+ oxidase and other NADPH oxidases. ML171 targets the NOX1 catalytic subunit
38
+ without affecting its cytosolic regulators, such as the NOXO1, NOXA1, or
39
+ RAC1 subunits. It effectively blocks NOX1 oxidase-dependent ROS-mediated
40
+ formation of extracellular matrix-degrading invadopodia in colon cancer
41
+ cells.
42
+ - source_sentence: |
43
+ What are the potential adverse effects of benzodiazepines?
44
  sentences:
45
+ - >-
46
+ The peak concentration (C max ) of perindopril refers to the highest
47
+ concentration of the drug in the plasma. The time to reach the C max (T max
48
+ ) indicates how long it takes for the drug to reach its maximum
49
+ concentration. These parameters are important in understanding the
50
+ absorption and distribution of perindopril in the body.
51
+ - >-
52
+ The Multi-drug Therapy (MDT) for leprosy uses a combination of three drugs:
53
+ Rifampicine, Dapsone, and Clofazimine.
54
+ - >-
55
+ Benzodiazepines can induce adverse effects such as oversedation, cognitive
56
+ impairment, motor impairment, and withdrawal. These effects may be
57
+ associated with the elimination half-life of the compounds, where long-term
58
+ use of compounds with a short elimination rate may induce withdrawal
59
+ syndromes, and accumulation-related effects of a long elimination rate may
60
+ include oversedation, cognitive dysfunction, and motor impairment.
61
+ - source_sentence: >
62
+ What is the role of resveratrol as an additive to paclitaxel in drug
63
+ coatings?
64
  sentences:
65
+ - >-
66
+ Traditional opioids are effective against severe pain but have problematic
67
+ side effects and limited efficacy against neuropathic pain. In contrast,
68
+ IBNtxA, a novel opioid analgesic, is a potent analgesic against thermal,
69
+ inflammatory, and neuropathic pain without causing side effects such as
70
+ respiratory depression, physical dependence, or reward behavior.
71
+ - >-
72
+ TXA is contraindicated in patients with severe kidney dysfunction due to the
73
+ risk of accumulation. However, dosages do not need to be modified in
74
+ patients with impaired liver function and elderly patients with no kidney
75
+ dysfunction.
76
+ - >-
77
+ Resveratrol is an additive to paclitaxel in drug coatings that helps
78
+ modulate adherence and release of the drug. It has been found to reduce drug
79
+ loss during passage through the hemostatic valve and sheath and during
80
+ floating in blood. Resveratrol has lower water-solubility compared to other
81
+ additives, which may contribute to its diminished drug loss. Previous
82
+ experiments and published data suggest that resveratrol is a useful coating
83
+ additive in drug delivery systems.
84
+ - source_sentence: >-
85
+ What are the most common nonhematologic toxicities associated with OXi4503
86
+ infusion?
87
  sentences:
88
+ - >-
89
+ The concentration of tetracycline taken up by mineralizing cell systems,
90
+ such as enamel, bone, or dentin, may be influenced by the distinctive
91
+ protein produced by these systems and the cofactors required, as well as the
92
+ availability of calcium or other ions for chelating tetracycline. The amount
93
+ of tetracycline available and the fluorescence observed in tissues may vary
94
+ depending on the particular hard tissue system and the specific mineralizing
95
+ cell system. However, the absence of fluorescence should not be taken as an
96
+ assured absence of tetracycline, as fluorescence alone is not sufficient to
97
+ establish a quantitative assay for tetracycline.
98
+ - >-
99
+ The most common nonhematologic toxicities associated with OXi4503 infusion
100
+ are tumor pain, nausea and/or vomiting, cardiac symptoms (hypertension,
101
+ tachycardia, and QTc prolongation), and neurologic symptoms.
102
+ - >-
103
+ The recommended categories for stocking antidotes in hospitals are divided
104
+ into two. Firstly, 12 antidotes should be available in the hospital
105
+ emergency department for immediate use upon poisoned patient arrival.
106
+ Secondly, nine antidotes should be available in the pharmacy to be
107
+ administered within an hour of when the antidote is deemed necessary. Three
108
+ additional antidotes are recommended to be stocked by the hospital, although
109
+ they are not usually needed within the first hour of treatment.
110
+ - source_sentence: >-
111
+ What is the purpose of dabigatran and why was it prescribed to the
112
+ 71-year-old female?
113
  sentences:
114
+ - >-
115
+ Melatonin agonists may have side effects such as nausea, headache, elevated
116
+ liver enzyme levels, rebound insomnia, withdrawal symptoms, and addiction.
117
+ Contraindications include liver failure, renal failure, alcohol addiction,
118
+ and high lipid levels.
119
+ - >-
120
+ G-protein coupled receptors, like OXTR and MOR, can form homo- or
121
+ hetero-dimers, which means they can associate with another molecule of the
122
+ same receptor or with receptors from other families. This physical
123
+ association has been shown to modulate receptor binding and function. For
124
+ example, in MOR-alpha2A-adrenergic receptor dimers, the activation of MOR by
125
+ morphine inhibits the adjacent alpha2A-receptor by blocking its ability to
126
+ activate the G-proteins, even in the presence of noradrenaline.
127
+ - >-
128
+ Dabigatran is prescribed for stroke prevention in patients with atrial
129
+ fibrillation. Atrial fibrillation increases the risk of blood clots forming
130
+ in the heart, which can then travel to the brain and cause a stroke.
131
+ Dabigatran is an anticoagulant that helps prevent the formation of blood
132
+ clots, reducing the risk of stroke in patients with atrial fibrillation.
133
  pipeline_tag: sentence-similarity
134
  library_name: sentence-transformers
135
+ datasets:
136
+ - miriad/miriad-4.4M
137
  ---
138
 
139
  # SentenceTransformer based on google/embeddinggemma-300m