MPGDHRRIRGPEESQPPQLYAADEEEAPGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRRAPFAGRRRRAPPGGCEERELALALQEALEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGVEMYDLVVGCGLSLAPGPAPTWLLDPTRLEEERAAAGLTVALMPVLNQVAGLLGSGEGGLTESWAEAVRLGLEGCQRLYPVLQQSLVRAARRRGAAAQP	This protein is part of the following components: cytosol, nucleoplasm, nucleus, cytoplasmic exosome (RNase complex), nucleolus, exosome (RNase complex), nuclear exosome (RNase complex), and cytoplasm. This protein is involved in the following processs: nuclear mRNA surveillance, RNA phosphodiester bond hydrolysis, exonucleolytic, regulation of mRNA stability, nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5', exonucleolytic catabolism of deadenylated mRNA, rRNA catabolic process, isotype switching, rRNA processing, polyadenylation-dependent snoRNA 3'-end processing, U4 snRNA 3'-end processing, DNA deamination, and positive regulation of isotype switching. This protein does not enable the following function: exoribonuclease activity. This protein is active in the following component: nucleolus. This protein is located in the following components: nucleolus, cytoplasm, nucleus, cytosol, and nucleoplasm. This protein enables hydrolase activity: exoribonuclease activity. This protein is involved in metabolic process: exonucleolytic catabolism of deadenylated mRNA, DNA deamination, rRNA processing, RNA phosphodiester bond hydrolysis, exonucleolytic, isotype switching, rRNA catabolic process, polyadenylation-dependent snoRNA 3'-end processing, U4 snRNA 3'-end processing, nuclear mRNA surveillance, and nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'. This protein enables RNA binding: RNA binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein enables the following function: RNA binding.
MRPRATTICSLFFLLRVLAEPAKNSDFYLPGDYLLGGLFTLHANMKGIVHLDYLQVPMCKEYETKVIGYNLMQAMRFAVEEINNDSSLLPDVLLGYEMVDVCYVSNNVQPVLYFLAQEDDLLPIQENYSNYVSRVVAVIGPDNSDAVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTAPSADHHIEAMVQLMLHFRWNWIIVLVSGDTYGRDNGQLLGDRLARGDICIAFQETLPTVQPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYNFFNEVLRQNFTGAVWIASESWAIDPVLHNLTELRHMGTFLGITIQSVPIPGFSEFRVRDPQAGPPPLSRTSQRSTCNQECDSCLNGTLSFNNVLRLSGERVVYSVYSAVYAVAHALHSLLGCDHGTCTKTEVYPWQLLKEIWKVNFTLLDHQISFDPQGDMALHLEIVQWQWDLSQNPFQSVASYYPLQRQLKTIQDISWHTINNTIPVSMCSKRCQSGQKKKPVGIHICCFECIDCLPGTFLNQTEDEYECQACPSNEWSHQSEASCFKRRLAFLEWHEAPTIVVALLAALGFLSTLAILVIFWRHFQTPMVRSAGGPMCFLMLTLLLVAYMVVPVYVGPPKVSTCFCRQALFPLCFTICISCIAVRSFQIVCVFKMASRFPRAYSYWVRYQGPYVSMAFITVLKMVTVVIGMLATGLNPTTRIDPDDPKIMIVSCNPNYRNSLFFNTGLDLLLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSVSLCTFMSAYNGVLVTIMDLLVTVLNLLAISLGYFGPKCYMILFYPERNTPAYFNSMIQGYTMRRD	This protein is part of the following components: plasma membrane, membrane, and integral component of membrane. This protein is involved in the following processs: response to stimulus, signal transduction, sensory perception of taste, and G protein-coupled receptor signaling pathway. This protein is located in the following components: membrane, integral component of membrane, and plasma membrane. This protein is involved in signal transduction: signal transduction, and G protein-coupled receptor signaling pathway. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables the following function: G protein-coupled receptor activity.
MSLLIKNGTIVNDDAIFKSDVLVLDGRIVEIAPSIQPTPGLEVVDATDRLVIPGGIDPHTHMQLPFMGEIAKDDFHRGTEAAVAGGTTMIIDFVIPTKGESLLVAYDRWRGWADPKVVCDYGLSMAITSWGPEIAKEMEIVTGAEYGINSFKFFLAYAGVFMVRDEEFYQGMIQCAKLRALARVHAENGSVIAERCEHLLSSGITGPEGHTQSRPEELEAEATFRACTMASQANCPLYVVHVMSKGAAAAIAHHRKKGAVVFGEPIAAGLATDGSHYYNEDWLHAARYVMSPPLSRDPSTPSALMKLLAAGELHLTATDNCTFDCQQKSLGKDDFTKIPNGVNGVEDRMSVVWDKGVHAGIIDPMRFVAVTSTMAAKIFNCYPQKGRIAVGSDADIVIWNANATRTISKDTHHHAIDFNIFEGMQVHGVPEITISRGRTVWANGQLKTVQGSGQFIPLAPDSQIVFSAVDNRKKAMEPVKIDRIPYEPSALQTPDANANIVVKAPVRAAIPPGGASSIQF	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: pyrimidine nucleobase catabolic process, and nucleobase catabolic process. This protein is located in the following component: cytoplasm. This protein enables hydrolase activity: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, dihydropyrimidinase activity, and hydrolase activity. This protein is involved in metabolic process: pyrimidine nucleobase catabolic process, and nucleobase catabolic process. This protein enables metal ion binding: metal ion binding. This protein is part of cytoplasm: cytoplasm. This protein is part of cytosol: cytosol. This protein enables the following functions: hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, dihydropyrimidinase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, and metal ion binding.
MISYYFQGFALGAAMILPLGPQNAFVMNQGIRRQYHLMIALLCALSDLVLISAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGLGALKTAMSSNLELASAEVMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLAMEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINILVGVVMWLIAFQLAREGVAHMHALFN	This protein is part of the following components: integral component of membrane, membrane, and plasma membrane. This protein is involved in the following processs: arginine transmembrane transport, arginine transport, and amino acid transport. This protein is located in the following components: integral component of membrane, plasma membrane, and membrane. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in cation transport: arginine transmembrane transport. This protein enables the following function: arginine transmembrane transporter activity.
MVATPSISSQTKGVVRQVIGPVLDVEFPAGKLPKILNALRIEAKNPAGQDIALTAEVQQLLGDHRVRAVAMSGTDGLVRGMEAIDTGAPISVPVGEATLGRIFNVLGEPVDEQGPVNTKDTAPIHRAAPKLTDLETKPKVFETGIKVIDLLAPYRQGGKVGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYEEFKESGVINADDLTQSKVALCFGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFVDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGELQERITSTLEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLARALAAKGIYPAVDPLDSTSTMLQPSVVGDEHYKTARAVQSTLQRYKELQDIIAILGLDELSEEDRLTVDRARKIEKFLSQPFFVAEIFTGMSGKYVKLEDTIAGFNMILSGELDDLPEQAFYLVGNIDEVKAKAEKIKSEK	This protein is part of the following components: membrane, thylakoid membrane, thylakoid, and proton-transporting ATP synthase complex, catalytic core F(1). This protein is involved in the following processs: ATP biosynthetic process, proton transmembrane transport, ATP synthesis coupled proton transport, ATP metabolic process, and ion transport. This protein is located in the following components: thylakoid membrane, membrane, thylakoid, and plasma membrane-derived thylakoid membrane. This protein is involved in metabolic process: ATP metabolic process, and ATP biosynthetic process. This protein enables catalytic activity: proton-transporting ATP synthase activity, rotational mechanism. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of membrane: thylakoid membrane, and membrane. This protein is involved in cation transport: proton transmembrane transport, ATP synthesis coupled proton transport, and ion transport. This protein enables the following functions: proton-transporting ATP synthase activity, rotational mechanism, ATP binding, nucleotide binding, and proton-transporting ATPase activity, rotational mechanism.
MRVLALLLAVKAACVLLVSSLTGTGAVNNSGRWWGIVNVASSGNLLTNSKNVQLVLDPSLALLSRRQRKLIRQNPGILHAIAAGLHTAIKECKWQFRNRRWNCPTTHSPNVFGKIVNRGCRETAFVFAITSAGVTHAVARSCSEGAIESCTCDYRRRGPGGPDWHWGGCSDNVEFGRMFGREFVDSSERGRDLRYLTNLHNNEAGRMTVASEMQQECKCHGMSGSCTVRTCWMRLPSFRLVGDYLKDRFDGASRVVYANKGSNRASHRADPRHLEPENPAHKLPSSRDLVYFEKSPNFCSYNGKTGTHGTSGRTCNSSSPALDGCELLCCGRGYKTRMEQVTERCHCTFHWCCHVSCLNCTSTQTVHQCL	This protein is part of the following components: extracellular region, and extracellular space. This protein is involved in the following processs: brain segmentation, Wnt signaling pathway, cell differentiation, nervous system development, midbrain-hindbrain boundary development, canonical Wnt signaling pathway, cell fate commitment, hindbrain development, multicellular organism development, fourth ventricle development, cerebellum morphogenesis, and neuron differentiation. This protein is active in the following component: extracellular space. This protein is located in the following component: extracellular region. This protein is involved in signal transduction: Wnt signaling pathway, and canonical Wnt signaling pathway. This protein is part of extracellular region: extracellular region. This protein enables the following functions: signaling receptor binding, frizzled binding, and cytokine activity.
MKYLAAYLLLTVGGKQSPSASDIESVLSTVGIEAEAERVESLISELNGKNIEELIAAGNEKLSTVPSAGAVATPAAGGAAGAEATSAAEEAKEEEAAEESDEDMGFGLFD	This protein is part of the following components: cytosol, ribosome, and cytosolic large ribosomal subunit. This protein is involved in the following processs: translational elongation, cytoplasmic translational elongation, and translation. This protein is located in the following components: cytosol, and ribosome. This protein is involved in metabolic process: cytoplasmic translational elongation, and translational elongation. This protein is part of cytosol: cytosol. This protein is involved in translation: translation. This protein enables structural constituent of ribosome: structural constituent of ribosome. This protein is part of ribosome: ribosome. This protein enables the following function: structural constituent of ribosome.
MESYLEENFGGVKAKNSSEEALRRWRKLCGVVKNPKRRFRFTANLDKRGEAQAIKHANHEKLRVAVLVSKAALQFIQGLSLRSEYVVPEEVKAAGFQICADELGSIVEGHDSKKLITHGGVTGIADKLATSPADGLSTAEESIKRRQDVYGLNKFTESEVRSFWVFVWEALQDTTLIILAVCAFVSLVVGIAMEGWPKGAHDGLGIVASILLVVFVTATSDYRQSLQFKDLDKEKKKIQVQVTRNGFRQRLSIYDLLPGDVVHLAIGDQVPADGLFISGFSLLINESSLTGESEPVVVNEDNPFLLSGTKVQDGSCKMLITTVGMRTQWGKLMATLSEGGDDETPLQVKLNGVATIIGKIGLFFAVITFIVLSQGLISKKYHEGLLLSWSGDDALEMLEHFAIAVTIVVVAVPEGLPLAVTLSLAFAMKKMMNDKALVRHLAACETMGSATTICSDKTGTLTTNHMTVVKACICGNIKEVNNPKNASDLCSELPETVVKTLLESIFNNTGGEVVIDQDGKYQILGTPTETALLEFALSLGGNFKAKRDETKIVKMEPFNSTKKRMCVVLKLPGGGCRAHCKGASEIVLAACDKFMDETGAVVPLDKTTADKLNGIIESFANEALRTLCLGYREMEEGFSVEEQIPLQGYTCIGIVGIKDPVRPGVRESVATCRSAGIMVRMVTGDNINTAKAIARECGILTEDGLAIEGPEFREKSLDELLKLIPKIQVMARSSPLDKHTLVKHLRTTFNEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKESADVIILDDNFSTIVTVAKWGRSVYVNIQKFVQFQLTVNVVALLVNFSSACFTGNAPLTAVQLLWVNMIMDTLGALALATEPPNDDLMKREPVGRTGKFITNVMWRNILGQSFYQFIVMWYLQTQGKSMFGLDGPDAEVVLNTIIFNSFVFCQVFNEISSREMEKINVLRGILKNYVFLGVLTSTVVFQFIMVQFLGEFANTIPLTRLQWIASVLLGLIGMPISAIIKLLPVGSS	This protein is part of the following components: intracellular membrane-bounded organelle, membrane, and integral component of membrane. This protein is involved in the following processs: calcium ion transmembrane transport, ion transport, and calcium ion transport. This protein is active in the following components: intracellular membrane-bounded organelle, and integral component of plasma membrane. This protein is located in the following components: membrane, and integral component of membrane. This protein enables metal ion binding: metal ion binding. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in cation transport: calcium ion transmembrane transport, ion transport, and calcium ion transport. This protein enables the following functions: ATPase-coupled cation transmembrane transporter activity, nucleotide binding, P-type calcium transporter activity, calmodulin binding, metal ion binding, and ATP binding.
MAKKRDRIVNTQPFISDDASVASSRKRSKVPKTHQKQEKLIEAGMSEKIMKQALAQQKEVADEENAERNPSSAAFAVAGAATAGEEQKILEEEEDDIDDFDGTFENQSQFDKQEEINEDDEKLFESFLNKNAPPQRTLTDIIIKKLKDKDADLAEEERPDPKMDPAITKLYKGVGKFMSEYTVGKLPKAFKLVTSMEHWEDVLYLTEPEKWSPNALYQATRIFASNLKDRQVQRFYNYVLLPRVREDIRKHKKLHFALYQALKKSLYKPSAFNQGILFPLCKSGTCNLREAVIIGSILEKCSIPMLHSCVALNRLAEMDYCGTTSYFIKVLLEKKYCMPYRVLDALVAHFMRFVDDIRVMPVIWHQSLLTFVQRYKYEILKEDKEHLQTLLQRQKHHLVTPEILRELKDSRNRGEKEDPMVDNFAPVPAKEDRFDIPEVPMEED	This protein is part of the following components: nucleus, nucleoplasm, preribosome, small subunit precursor, cytoplasm, and nucleolus. This protein is involved in the following processs: embryo sac development, rRNA processing, pollen development, and ribosome biogenesis. This protein is active in the following components: cytoplasm, and nucleolus. This protein is located in the following components: nucleus, nucleoplasm, and nucleolus. This protein is involved in metabolic process: rRNA processing. This protein enables RNA binding: snoRNA binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables the following function: snoRNA binding.
MPDLKTMMLNFGPQHPAAHGVLRLVLEMDGEVIERADPHIGLLHRGTEKLIEHKTYLQALPYFDRLDYVSPMSQEHAYSLCVEKLLQCEIPIRAKYLRVLFCELTRILNHLLNISSQALDVGAMTPLLWLFEEREKILEFYERASGARFHAAYIRPGGLAADIPEGLIEDIAKFIEQFPKYIDDVDELLTENRIWKQRTVGISEISIKQALDWGFSGPMLRAAGLAWDLRKSQPYEIYDQLDFDIPIGQNGDCYDRYLVRMAEIRQSVSLVKQCIEKMPEGPIKTEDRKISPPPRAEMKESMEAMIHHFKLYSEGYHVPEGEAYVAVEAPKGEFGVYIVSDGTNRPYRCRIRAPGFAHLQALDFMAKGHMLADIAAIIGSLDIVFGEIDR	This protein is part of the following components: membrane, and plasma membrane. This protein is located in the following components: membrane, and plasma membrane. This protein enables catalytic activity: oxidoreductase activity, acting on NAD(P)H, and NADH dehydrogenase (quinone) activity. This protein enables nucleotide binding: NAD binding. This protein is part of membrane: plasma membrane, and membrane. This protein enables the following functions: NAD binding, NADH dehydrogenase (quinone) activity, oxidoreductase activity, acting on NAD(P)H, and quinone binding.
MEKKLPRRLEGKVAIVTASTQGIGFGITERFGLEGASVVVSSRKQANVDEAVAKLKSKGIDAYGIVCHVSNAQHRRNLVEKTVQKYGKIDIVVCNAAANPSTDPILSSKEAVLDKLWEINVKSSILLLQDMAPHLEKGSSVIFITSIAGFSPQGAMAMYGVTKTALLGLTKALAAEMAPDTRVNAVAPGFVPTHFASFITGSSEVREGIEEKTLLNRLGTTGDMAAAAAFLASDDSSYITGETLVVAGGMPSRL	This protein is part of the following components: cytosol, and peroxisome. This protein is involved in the following processs: lipid metabolic process, response to indolebutyric acid, indolebutyric acid metabolic process, root hair elongation, and fatty acid metabolic process. This protein is located in the following components: cytosol, and peroxisome. This protein is involved in metabolic process: indolebutyric acid metabolic process. This protein enables catalytic activity: oxidoreductase activity. This protein is involved in lipid metabolic process: lipid metabolic process, and fatty acid metabolic process. This protein is part of cytosol: cytosol. This protein enables the following function: oxidoreductase activity.
MNKANMLRTDKDMQIILFSEVSVGISANSILFIAHVCMILGENRPKPIDLYIAFLSLTQLMLLITMGLIAVDMFLSQGIWDSTTCQSLIYLHRLLRGLSLCATCLLNILWTITLSSRSFCSTKFKHKSPHHISGAFIFFCVLYMSFSSHLFISIIATHNLTSENFIYVTQSCSLLPLSYSRTSMFSAPMAIREAFLVSLMALSSGYMVALLWRHKKQAQHLHSTSLSSKASPEQRATRTILLLMSFFVVLYILENAVFYSRIKFKDGSILYCVQIILCHSYATVNPFVFICTEKHIIKFWESKCGRIVNI	This protein is part of the following components: membrane, plasma membrane, and integral component of membrane. This protein is involved in the following processs: G protein-coupled receptor signaling pathway, signal transduction, and response to pheromone. This protein acts upstream of or within the following process: sensory perception of chemical stimulus. This protein is located in the following components: plasma membrane, membrane, and integral component of membrane. This protein is involved in signal transduction: G protein-coupled receptor signaling pathway, and signal transduction. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables the following functions: G protein-coupled receptor activity, and pheromone receptor activity.
MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRSGRVADFTEQYNEQYGAVRTPYTMGYGDSLYYNNAYGALDAYYKRCRAARSYEAVAAAAASAYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAAAAAAAAAAAVTAASSSYYGRDRSPLRRATGPVPTVGEGYGYGHESELSQGSSAARNSLYDMARYEREQYADRARYSAF	This protein is part of the following components: cytoplasmic stress granule, nucleus, cytosol, cytoplasm, nucleolus, nuclear speck, and nucleoplasm. This protein is involved in the following processs: RNA splicing, negative regulation of translation in response to stress, mRNA cis splicing, via spliceosome, entrainment of circadian clock by photoperiod, positive regulation of muscle cell differentiation, response to arsenic-containing substance, negative regulation of translational initiation, mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome, gene silencing by RNA, mRNA processing, circadian regulation of translation, miRNA mediated inhibition of translation, regulation of nucleocytoplasmic transport, cap-independent translational initiation, IRES-dependent translational initiation of linear mRNA, cell differentiation, and negative regulation of translation. This protein is active in the following component: nuclear speck. This protein is located in the following components: nucleolus, cytoplasmic stress granule, nucleoplasm, cytosol, nucleus, nuclear speck, and cytoplasm. This protein is involved in metabolic process: IRES-dependent translational initiation of linear mRNA, cap-independent translational initiation, RNA splicing, mRNA processing, and mRNA cis splicing, via spliceosome. This protein enables metal ion binding: zinc ion binding, and metal ion binding. This protein enables RNA binding: RNA binding, pre-mRNA intronic binding, pre-mRNA intronic pyrimidine-rich binding, miRNA binding, mRNA 3'-UTR binding, mRNA binding, and pre-mRNA binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein enables the following functions: metal ion binding, nucleic acid binding, miRNA binding, pre-mRNA intronic binding, pre-mRNA intronic pyrimidine-rich binding, mRNA 3'-UTR binding, cyclin binding, RNA binding, zinc ion binding, mRNA binding, and pre-mRNA binding.
MRWEFLPCLLLLISNNKIFGFKVPSINFEMLKDEGFEVSIPDEPGIQRVFYMFQIDDTCPALMDYITEAVNGSWVSKQKMSLQNNDKLQISMLVQFNEEIFEKSETRVIINTRLLTTKDSSSRGITFLTGEGECQAYLAPAQQAKRCKAAQTIVSNGRHTCQGELIFEDNFSEAQLNKTTWKHDIRQRMYHVEEELVAFDDAARNCFVKEGELHIVPTIATEVTDGSFKLGDRCTAVESPEQECNIAHGIFYSIKPPVFSAQIHTRNSFSFKFGKIVVRAKLPKGDWLFPYLMLQPVSTYAETHYAKQLRIAYARGNANLRTKQGDDISGNHLYGGGVVWHHGNAVQFLKDKISNSHYGDDFHNYTMIWQRDKITLMVDDEVYGELYDGLPFFNEKCFIIFGVTVGGFLNFDDSLLAKDVKPYKNREPRAALSFWQHRDAWAPTWGRHSAMVIDYVRVYAE	This protein is part of the following component: extracellular region. This protein is involved in the following processs: innate immune response-activating signal transduction, regulation of innate immune response, immune system process, innate immune response, pattern recognition receptor signaling pathway, and carbohydrate metabolic process. This protein does not enable the following function: beta-glucanase activity. This protein is located in the following component: extracellular region. This protein enables hydrolase activity: beta-glucanase activity, and hydrolase activity, hydrolyzing O-glycosyl compounds. This protein is involved in signal transduction: pattern recognition receptor signaling pathway, and innate immune response-activating signal transduction. This protein is part of extracellular region: extracellular region. This protein is involved in carbohydrate metabolic process: carbohydrate metabolic process. This protein enables the following functions: hydrolase activity, hydrolyzing O-glycosyl compounds, pattern recognition receptor activity, lipopolysaccharide binding, (1->3)-beta-D-glucan binding, and carbohydrate binding.
MKNNCTSLKSSIDEEDELKTDHEIDLEKGLLPEYDSKEEGALPLYSDHARLSNSPNTHRENNPSRSTDNSSPLLIKLLISFTSIILFNAPAVCYLKYKDAFFKNYGAAEWTLFGFWCLVCTLALIFLTYFYETWTKAVKVTVIFLAQCVKACGKGIKHFLKKWENMPMAFSEVFLFNIFGGALRIISRHFFGKRWGLKCSLADHIIFAILSILVFIAETVKPGSIRVNLIRKMGHEAKQQVNEYTAIPLHEMNPESEA	This protein is part of the following components: integral component of membrane, and membrane. This protein is involved in the following processs: negative regulation of ascospore formation, and meiotic drive. This protein is located in the following components: membrane, vacuole, cytoplasm, vacuolar membrane, and integral component of membrane. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables the following function: molecular_function.
MCAYRLQYSLRFNIYDRFENVCFEAQLLQDEIDSLCFLFSKYFNQSLIVDSKGLTFFTEFNKCIVSIKSSFENQANNTDNIHNVKNIFSIFLRDEFIKQVPHFRTIMQYLQKYYNPTPAPDVDAIMCQSCKPANKIQCFECKCKYLASSLSTLDAGLQNGWDIFLRPMFGMPLMLYVLLRTDYKNESDIINENNLITQIFVQFFYNLICDKAYSLYTKRDMCVPFVKECKKATVGLRQEDHERVLSILSAQCNGCSTVANGDRLLLPFKNFMIEMGRNTKMKKVNKIASTVLIGFYLRHYLESLPNKAYPVAELELRNVCRFIMSKYSDENINLLIHKLKLIKIDICNVLMTEMIVPETFIRHIITKYQLDNEISLLIELNHDCFNK	This protein is part of the following components: host cell nucleus, and host cell cytoplasm. This protein is located in the following components: host cell nucleus, and host cell cytoplasm.
MERQQIIESLRRIIPTESTEYNERLISLGESFLEWSKYKHNLKATEELCRPYMAAHLACELLSNDLNLEINLLATPIPKKKYYKLFTYFQEILSPLTKSLAAKDDLMETITYLCTKLGGSTAIPYVKQLVKAVVTNDMRIEHKRGIIIAAYLLVSAKAFGKDELHINHTERRKAQSVLQDTSSALQIQYWMHVLSESWQYKEIPLNGIEGYESQKQRIKPWSGIASMIQIDYEKRLQNYPIWKACIEERIQYYKSQLEKDGTAS	This protein is part of the following components: DNA replication preinitiation complex, nuclear replication fork, cytosol, nucleus, chromatin, nuclear pre-replicative complex, and nuclear origin of replication recognition complex. This protein is involved in the following processs: DNA replication, DNA replication initiation, and mitotic DNA replication initiation. This protein contributes to the following function: DNA replication origin binding. This protein is located in the following components: nucleus, nuclear replication fork, chromatin, and cytosol. This protein is involved in metabolic process: DNA replication initiation, mitotic DNA replication initiation, and DNA replication. This protein enables DNA binding: DNA replication origin binding, and DNA binding. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein enables the following functions: DNA binding, DNA replication origin binding, and protein binding.
MNYFPIFANLAGRPVLVVGGGAVAARKISLLLKAGAEVRVAAKHLNAELSALAAENKILWLAEEFRAEHIRTVFLIIAASSDQALNRRVFHLAESCQKPVNVVDDRDHCSFIFPSVIDRNPVQIAVSSSGSAPVLARLLRERLEALLPPSLGDMAEISGRWRDAVKGKLKSVTERRRFWEKQFNGRFAALVKNRQNTLAERELAGQLEQSRQNDQGGSVSLVGAGPGDAGLLTLKGLQEIQQADVVLYDALVSDGILSLVRRDAERIFVGKRARGERTPQEDTNALMVRLAREGRRVVRLKGGDPFVFGRGGEELETLARHQIPFSVVPGITAAVGATAYAGIPLTHRDYAQSAVFVTGHRKADAPDIEWQTLARSRQTLVIYMGALKAALIAERLQQHGRSPDTPAAVISQGTLPAQKTATGTLANLAELAETAPNPALIVIGEVVGLHEKLAWFGENGEGENRVGQTYPALGGLNAGQRAA	This protein is involved in the following processs: metabolic process, siroheme biosynthetic process, methylation, cobalamin biosynthetic process, and porphyrin-containing compound biosynthetic process. This protein is involved in metabolic process: cobalamin biosynthetic process, metabolic process, siroheme biosynthetic process, and porphyrin-containing compound biosynthetic process. This protein enables catalytic activity: sirohydrochlorin ferrochelatase activity, precorrin-2 dehydrogenase activity, oxidoreductase activity, lyase activity, ferrochelatase activity, and catalytic activity. This protein enables nucleotide binding: NAD binding. This protein enables transferase activity: uroporphyrin-III C-methyltransferase activity, methyltransferase activity, and transferase activity. This protein is involved in methylation: methylation. This protein enables the following functions: oxidoreductase activity, NAD binding, precorrin-2 dehydrogenase activity, sirohydrochlorin ferrochelatase activity, catalytic activity, transferase activity, uroporphyrin-III C-methyltransferase activity, methyltransferase activity, ferrochelatase activity, and lyase activity.
MVFGSRPPALTEANIGDQSGKVFIVTGATSGYGLLLSTYLYQNNGTVYLAARNAKKTAEVIADLKQRFPASRGRLDSISLNLSDLSTIKKSAEEFLAKETRLHVLWNNAGVMFPPAGSTTSQGYELQLGTNNVGPHLFTKLLYPTLAATAKEAPKNTVRVVWVSSDAASWAPKPAIDFNNLDYRRNESDRSKYGRSKAGTVMQAVELARRARKDGSGIVSIALDPGIANTGLQRDMGRLMSTMVKLIANKPEIGAYTQLFAGLSPEITAEVAEKEWVVPPGKIGCPRRDLFTDTETSRKWWEWNEEQVKAYL	This protein is part of the following component: cellular_component. This protein is involved in the following processs: cellular response to farnesol, and secondary metabolite biosynthetic process. This protein is active in the following component: cellular_component. This protein is involved in metabolic process: secondary metabolite biosynthetic process. This protein enables catalytic activity: oxidoreductase activity. This protein enables the following function: oxidoreductase activity.
MADKSTEVEKAIDPIIDLGNLLFIDREPLQGDAEEGLEERARKNTQLLFNNIWQLEQKRVEEAIIVTLPAATYRLPREKKLPEKKEPTKWEKYAKEKGIEKRKKDKKVFDEATKEWKPTYGYRRGNDNTKDWLIEIPDNAEDPNKDFFAERREKKKERVAKNEMQRMKNLARQMKTTVKTGPSTDKMIGVGIDAKDKSKQDVRFAVDRAKLATASAGKFQEGLKGEKANIKTGKKRKFESNEAPVSAEKERALQILQRMKSKKAKIVEEKASAVAGPLREKKEKQEKKGAKEATRQKSQIHRQQWFKNKVDSKKKGTGGAKKKGANKRK	This protein is part of the following components: nucleolus, preribosome, large subunit precursor, and nucleus. This protein is involved in the following processs: ribosomal large subunit biogenesis, ribosome biogenesis, ribosomal large subunit export from nucleus, ribosomal large subunit assembly, and endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). This protein is active in the following component: nucleolus. This protein is located in the following components: nucleus, and nucleolus. This protein is involved in metabolic process: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). This protein is part of nucleus: nucleus.
MTFRKSFDCYDFYDRAKVGEKCTQDDWDLMKIPMKAMELKQKYGLDFKGEFIPTDKDMMEKLFKAGFEMLLECGIYCTDTHRIVKYTEDEIWDAINNVQKEFVLGTGRDAVNVKKRSVGDKAKPIVQGGPTGSPISEDVFMPVHMSYALEKEVDTIVNGVMTSVRGKAPVPKSPYEVLAAKTETRLIKNACAMAGRPGMGVOGPETSLSAQGNISADCAGGMTCTDSHEVSQLNELKIDLDAISVIAHYKGNSDIIMDEQMPIFGGYAGGIEETTIVDVATHINAVIMSSASWHLDGPVHIRWGSTNTRETLTIAGWACATISEFTDILSGNQYYPCAGPCTEMCLLEASAQSITDTASGREILSGVASAKGVVTDKTTGMEARMMGEVARATAGVEISEVNVILDKLVALYEKNYASAPAGKTFQECYDVKTVTPTEEYMQVYDGARKKLEDLGLVF	This protein is involved in the following processs: methylation, and methanogenesis. This protein is involved in metabolic process: methanogenesis. This protein enables transferase activity: transferase activity, methyltransferase activity, and monomethylamine methyltransferase activity. This protein is involved in methylation: methylation. This protein enables the following functions: methyltransferase activity, transferase activity, and monomethylamine methyltransferase activity.
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQEKRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGSHYSYSENRVEKDGLILTSRGPGTSFEFALKIVEVLVGKEVADQVKAPLVLKD	This protein is part of the following components: PML body, cytoplasm, nucleus, perinuclear region of cytoplasm, chromatin, presynapse, cytosol, cell body, neuron projection, mitochondrial intermembrane space, membrane raft, mitochondrial matrix, membrane, synapse, endoplasmic reticulum, nucleoplasm, mitochondrion, and plasma membrane. This protein is involved in the following processs: methylglyoxal catabolic process to lactate, regulation of neuron apoptotic process, DNA repair, cellular response to reactive oxygen species, positive regulation of L-dopa decarboxylase activity, regulation of histone ubiquitination, autophagy, negative regulation of TRAIL-activated apoptotic signaling pathway, histone modification, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of protein K48-linked deubiquitination, negative regulation of protein export from nucleus, positive regulation of superoxide dismutase activity, negative regulation of protein binding, positive regulation of transcription regulatory region DNA binding, positive regulation of gene expression, membrane hyperpolarization, mitochondrion organization, positive regulation of mitochondrial electron transport, NADH to ubiquinone, hydrogen peroxide metabolic process, regulation of mitochondrial membrane potential, negative regulation of oxidative stress-induced cell death, synaptic transmission, dopaminergic, positive regulation of acute inflammatory response to antigenic stimulus, guanine deglycation, peptidyl-cysteine deglycation, negative regulation of ubiquitin-specific protease activity, positive regulation of reactive oxygen species biosynthetic process, negative regulation of protein acetylation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, positive regulation of protein localization to nucleus, glyoxal metabolic process, negative regulation of extrinsic apoptotic signaling pathway, glyoxal catabolic process, inflammatory response, cellular detoxification of methylglyoxal, regulation of inflammatory response, negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway, proteolysis, negative regulation of hydrogen peroxide-induced neuron death, positive regulation of peptidyl-serine phosphorylation, positive regulation of pyrroline-5-carboxylate reductase activity, positive regulation of DNA-binding transcription factor activity, detection of oxidative stress, response to hydrogen peroxide, negative regulation of protein catabolic process, positive regulation of NAD(P)H oxidase activity, peptidyl-lysine deglycation, negative regulation of protein phosphorylation, cellular response to oxidative stress, negative regulation of hydrogen peroxide-induced cell death, insulin secretion, positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, membrane depolarization, positive regulation of tyrosine 3-monooxygenase activity, peptidyl-arginine deglycation, protein deglycation, methylglyoxal removal, positive regulation of oxidative phosphorylation uncoupler activity, cellular response to hydrogen peroxide, regulation of androgen receptor signaling pathway, protein stabilization, negative regulation of protein ubiquitination, negative regulation of protein kinase activity, glutathione deglycation, single fertilization, negative regulation of cell death, negative regulation of neuron death, protein deglycosylation, negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway, negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, cellular response to glyoxal, adult locomotory behavior, negative regulation of reactive oxygen species biosynthetic process, regulation of histone acetylation, positive regulation of L-dopa biosynthetic process, positive regulation of interleukin-8 production, detoxification of copper ion, guanine deglycation, methylglyoxal removal, positive regulation of protein-containing complex assembly, lactate biosynthetic process, negative regulation of protein sumoylation, dopamine uptake involved in synaptic transmission, positive regulation of transcription by RNA polymerase II, cellular oxidant detoxification, negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway, negative regulation of ubiquitin-protein transferase activity, detoxification of mercury ion, negative regulation of oxidative stress-induced neuron death, negative regulation of neuron apoptotic process, glucose homeostasis, glycolate biosynthetic process, negative regulation of apoptotic process, negative regulation of gene expression, protein deglycation, glyoxal removal, guanine deglycation, glyoxal removal, positive regulation of androgen receptor activity, cellular detoxification of aldehyde, and positive regulation of dopamine biosynthetic process. This protein does not enable the following function: protein deglycase activity. This protein is not involved in the following processs: methylglyoxal metabolic process, protein deglycation, methylglyoxal removal, and protein deglycosylation. This protein is active in the following components: nucleus, and cytosol. This protein is located in the following components: membrane, neuron projection, cytosol, PML body, chromatin, plasma membrane, cytoplasm, mitochondrial matrix, endoplasmic reticulum, cell body, mitochondrion, synapse, nucleoplasm, membrane raft, nucleus, presynapse, perinuclear region of cytoplasm, and mitochondrial intermembrane space. This protein enables hydrolase activity: hydrolase activity, and peptidase activity. This protein is involved in metabolic process: glutathione deglycation, glycolate biosynthetic process, methylglyoxal metabolic process, methylglyoxal catabolic process to lactate, protein deglycation, methylglyoxal removal, protein deglycation, glyoxal removal, peptidyl-arginine deglycation, hydrogen peroxide metabolic process, cellular detoxification of methylglyoxal, guanine deglycation, guanine deglycation, methylglyoxal removal, protein deglycosylation, lactate biosynthetic process, guanine deglycation, glyoxal removal, peptidyl-lysine deglycation, glyoxal metabolic process, histone modification, glyoxal catabolic process, peptidyl-cysteine deglycation, and autophagy. This protein enables metal ion binding: mercury ion binding, cuprous ion binding, cupric ion binding, and copper ion binding. This protein enables catalytic activity: protein deglycase activity, glyoxalase (glycolic acid-forming) activity, oxidoreductase activity, acting on peroxide as acceptor, and peroxiredoxin activity. This protein is part of membrane: membrane, plasma membrane, and membrane raft. This protein is involved in cellular response to DNA damage stimulus: DNA repair. This protein is part of mitochondrion: mitochondrion. This protein enables RNA binding: RNA binding, and mRNA binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is involved in proteolysis: proteolysis. This protein is part of cytosol: cytosol. This protein is involved in regulation of transcription, DNA-templated: positive regulation of DNA-binding transcription factor activity, positive regulation of androgen receptor activity, and positive regulation of transcription by RNA polymerase II. This protein is involved in cation transport: dopamine uptake involved in synaptic transmission. This protein is involved in protein transport: insulin secretion. This protein enables the following functions: DNA-binding transcription factor binding, androgen receptor binding, mRNA binding, transcription coactivator activity, cupric ion binding, small protein activating enzyme binding, transcription factor binding, cuprous ion binding, protein-containing complex binding, mercury ion binding, superoxide dismutase copper chaperone activity, L-dopa decarboxylase activator activity, peroxiredoxin activity, oxygen sensor activity, peptidase activity, glyoxalase (glycolic acid-forming) activity, kinase binding, hydrolase activity, ubiquitin-specific protease binding, identical protein binding, copper ion binding, tyrosine 3-monooxygenase activator activity, enzyme binding, ubiquitin-like protein conjugating enzyme binding, protein deglycase activity, RNA binding, scaffold protein binding, cytokine binding, protein homodimerization activity, oxidoreductase activity, acting on peroxide as acceptor, DNA-binding transcription factor binding, and signaling receptor binding.
MDARKEGLPLETLFSDQYPQVRRWLAPFILACSLYFLLWIPVDQPSWVSALIKCQPILCLVVFLWAVAPGGSSTWLLQGALVCSAVGDACLIWPEAFFYGTAAFSVAHLFYLGAFGLTPLQPGLLLCTTLASLTYYSFLLLHLEQGMVLPVMAYGLILNSMLWRSLVWGGSASWGAVLFTFSDGVLAWDTFVYSLPFARLVTMSTYYAAQLLLILSALRNPGLKTH	This protein is part of the following components: cytoplasm, membrane, and integral component of membrane. This protein is involved in the following process: ether lipid metabolic process. This protein acts upstream of or within the following process: ether lipid metabolic process. This protein is located in the following components: membrane, cytoplasm, and integral component of membrane. This protein enables hydrolase activity: hydrolase activity, alkenylglycerophosphocholine hydrolase activity, and alkenylglycerophosphoethanolamine hydrolase activity. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of cytoplasm: cytoplasm. This protein is involved in lipid metabolic process: ether lipid metabolic process. This protein enables the following functions: alkenylglycerophosphocholine hydrolase activity, identical protein binding, hydrolase activity, and alkenylglycerophosphoethanolamine hydrolase activity.
MSTVEPLSDEGVAAGPRRIEVPRPPSIEEFTIVKPISRGAFGKVYLGRKAGRLYAVKVMKKADMINKNMVHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEAALALDYLHRHGIIHRDLKPDNMLISNQGHIKLTDFGLSRVTLNREINMIDILTTPSMAKPKHDYSRTPGQLLSLISSLGFYTPVGMKMPINPNSGGASDSLHEVISPLSMIEKENTPLSTKLFKTGLDTSPLTPVMPVRSLTPALLQSRERFGASTASSQSCMYLSSMESECCSSPRLEKDVKQTEDEMCSTGTSNSRPPLPSSREVLNSKDPKVLKKELESAISPISSNDCGSRQKLGTERSEITDTPVTTLDTKGIVRKCLSENKIWEEKLVARREMTNEMLETASSQQSPLFLKDPVQPVKEEEIFEKPGVKRSFELVDTSPCQELNYVKKTNAEYKRGCWISELSASKSTGLTTEIQSLMLSGEICESKEIMRCIDRQQTEKPLVPTVAKNLLCDLDADHEKDKEYMNSSLLCADDEKPLGALSADSDLSFPETSVSESHLEKQLVDLDKGVKDLSFEEPKAEDLLTMSPNCQEASRNGVEADVVQNCTMLCCEQDNHQKHTEETDTISSPSEKMTETVHLFRKNNVVFRSYNSPINVSNVSDPCSMASLDIMDLSPACSGSYPTAITPLQKTPRQGDAGTPYRTPKSVRRGAAPVEGERILGTPDYLAPELLLTKPHGSAVDWWALGVCLFEFLTGIPPFNDETPAQVFQNILKRDIPWPEGEEKLSDNAQNAIDILLTFDSTKRAGLKELKHHPLFHGVDWDNLQNQPMPFIPQPDDETDTSYFEARNNAQHLTVSGFSL	This protein is part of the following components: cytoplasm, microtubule organizing center, nucleus, cleavage furrow, cytoskeleton, and centrosome. This protein is involved in the following processs: cell division, mitotic cell cycle, G2/M transition of mitotic cell cycle, phosphorylation, peptidyl-serine phosphorylation, protein phosphorylation, cellular response to DNA damage stimulus, cell cycle, negative regulation of phosphoprotein phosphatase activity, and intracellular signal transduction. This protein is active in the following component: nucleus. This protein is located in the following components: nucleus, cleavage furrow, cytoplasm, centrosome, microtubule organizing center, and cytoskeleton. This protein is involved in signal transduction: intracellular signal transduction. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein is part of membrane: cleavage furrow. This protein is involved in cellular response to DNA damage stimulus: cellular response to DNA damage stimulus. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables transferase activity: protein serine/threonine kinase activity, protein kinase activity, transferase activity, and kinase activity. This protein is involved in phosphorylation: protein phosphorylation, peptidyl-serine phosphorylation, and phosphorylation. This protein is involved in cell cycle: mitotic cell cycle, and cell cycle. This protein is involved in cell division: cell division. This protein enables the following functions: transferase activity, protein kinase activity, nucleotide binding, ATP binding, protein threonine kinase activity, protein phosphatase 2A binding, protein serine kinase activity, kinase activity, and protein serine/threonine kinase activity.
MDVIPTEAIWWRLFLLFTAVGVLAAGTVTAFFIYSLFKYRSSGQALGEDQGTAGRIYRIMVESPVSGKSKYLLFVTGIIVMGLIVATIDETLYLEKSPPVEDALVVMVIGFQFGWQFEYSVGGETVTTLNYLVVPSDTLIEFRVTSRDVFHAFGIPEFKNKIDAIPGILNSMWIKTPDEPGKVYNAYCYELCGIGHSLMVGKVIVVDKEEFYNAYNSGPDVFSEYVNNVISKYK	This protein is part of the following components: integral component of membrane, respirasome, membrane, and plasma membrane. This protein is involved in the following processs: proton transmembrane transport, and electron transport chain. This protein is located in the following components: membrane, integral component of membrane, respirasome, and plasma membrane. This protein is involved in metabolic process: electron transport chain. This protein enables metal ion binding: metal ion binding, and copper ion binding. This protein enables catalytic activity: cytochrome-c oxidase activity, and oxidoreductase activity. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in cation transport: proton transmembrane transport. This protein enables the following functions: oxidoreductase activity, copper ion binding, cytochrome-c oxidase activity, and metal ion binding.
MTNQEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGKQDILNQTIDFEGFKLFMKTFLEAELPDDFTAHLFMSFSNKFPHSSPMVKSKPALLSGGLRMNKGAITPPRTTSPANTCSPEVIHLKDIVCYLSLLERGRPEDKLEFMFRLYDTDGNGFLDSSELENIISQMMHVAEYLEWDVTELNPILHEMMEEIDYDHDGTVSLEEWIQGGMTTIPLLVLLGLENNVKDDGQHVWRLKHFNKPAYCNLCLNMLIGVGKQGLCCSFCKYTVHERCVARAPPSCIKTYVKSKRNTDVMHHYWVEGNCPTKCDKCHKTVKCYQGLTGLHCVWCQITLHNKCASHLKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSVPEERQSTVKKEKSGSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSGGKQGERIYRKFQYLLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIEKANVGKHPPVAILPLGTGNDLARCLRWGGGYEGENLMKILKDIENSTEIMLDRWKFEVIPNDKDEKGDPVPYSIINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSATCKKLHESVEIECDGVQIDLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKGSDKRTTVTDAKELKFASQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVIRTSKSLPMQIDGEPWMQTPCTIKITHKNQAPMLMGPPPKTGLFCSLVKRTRNRSKE	This protein is part of the following components: membrane, glutamatergic synapse, plasma membrane, Schaffer collateral - CA1 synapse, synapse, cell junction, cytoplasm, and postsynaptic membrane. This protein is involved in the following processs: phosphatidic acid biosynthetic process, signal transduction, protein kinase C-activating G protein-coupled receptor signaling pathway, intracellular signal transduction, diacylglycerol metabolic process, lipid phosphorylation, phosphorylation, modulation of chemical synaptic transmission, response to bacterium, platelet activation, glycerolipid metabolic process, and regulation of postsynapse organization. This protein is active in the following component: plasma membrane. This protein is located in the following components: plasma membrane, membrane, postsynaptic membrane, cytoplasm, cell junction, and synapse. This protein is involved in signal transduction: protein kinase C-activating G protein-coupled receptor signaling pathway, signal transduction, and intracellular signal transduction. This protein enables metal ion binding: calcium ion binding, and metal ion binding. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of membrane: plasma membrane. This protein is part of cytoplasm: cytoplasm. This protein enables transferase activity: transferase activity, diacylglycerol kinase activity, kinase activity, and NAD+ kinase activity. This protein is involved in lipid metabolic process: glycerolipid metabolic process, and diacylglycerol metabolic process. This protein is involved in phosphorylation: lipid phosphorylation, and phosphorylation. This protein enables the following functions: lipid binding, calcium ion binding, metal ion binding, nucleotide binding, transferase activity, ATP binding, NAD+ kinase activity, diacylglycerol kinase activity, and kinase activity.
MNTSSRSSEPSKVADDVYVQTRWNNEFKHADYLPESLQKCLDQEKTVLERYSELVEVSKTVANESSQALVKHTTKPGDQLVRRVFQQPHQQISLMERYEKTRSYKPQWHAPWKLSKVINGHTGWVRCVCVDPVDNEWFATGSNDTTIKIWDLAAGKLKITLIGHVMSVRDIAISKRHPYMFSASEDKLVKCWDLERNTAIRDFHGHLSGVHTVDVHPSLDIIATAGRDAVVRLWDIRSRSEIMVLPGHKSPINKVKCLPVDPQIISCSGDATVRLWDIIAGKASKVLTHHSRNIRDLTLHPAEFSFASVSTNDVRSWKLPEGQLLTNFQSQNTGILNTVSINHDNVLLAGGDDGTLCFYDYKTGHKYQSMMTTEVAGSLESERSILCSTFDVTGTRLITGEGDKSIKIWKQVPDATEDTFPGLPWNPTLISQRF	This protein is part of the following components: Prp19 complex, cytoplasm, nucleus, and spliceosomal complex. This protein is involved in the following processs: mRNA splicing, via spliceosome, mRNA processing, and RNA splicing. This protein is located in the following components: cytoplasm, and nucleus. This protein is involved in metabolic process: mRNA processing, mRNA splicing, via spliceosome, and RNA splicing. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus.
MNLLPSNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKHEFLEGGVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPATHSGHVQIVDLANTEKPPVDIPAHEGVLCCITLNLQGTRIATASEKGTLIRIFDTSAGQLIQELRRGSQTANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCVCAFGTEPNAVIAICADGSYYKFLFNPKGECSRDVYAQFLEMTDEKI	This protein is part of the following components: cytosol, phagophore assembly site membrane, lysosome, extrinsic component of membrane, and phagophore assembly site. This protein is involved in the following processs: protein lipidation, cellular response to starvation, autophagy, autophagy of mitochondrion, protein localization to phagophore assembly site, autophagy of nucleus, and autophagosome assembly. This protein is active in the following components: cytosol, phagophore assembly site membrane, and extrinsic component of membrane. This protein is located in the following components: lysosome, and phagophore assembly site. This protein is involved in metabolic process: autophagy, autophagy of nucleus, autophagy of mitochondrion, and protein lipidation. This protein is part of membrane: phagophore assembly site membrane. This protein is part of cytosol: cytosol. This protein enables the following functions: phosphatidylinositol-3-phosphate binding, and phosphatidylinositol-3,5-bisphosphate binding.
ATDLQAGYVADSNFTEAWKKVVPNVDPPKTPSAFMXP	This protein is part of the following components: proton-transporting ATP synthase complex, catalytic core F(1), mitochondrial inner membrane, mitochondrion, and membrane. This protein is involved in the following processs: ATP synthesis coupled proton transport, ion transport, and ATP biosynthetic process. This protein is located in the following components: mitochondrial inner membrane, membrane, and mitochondrion. This protein is involved in metabolic process: ATP biosynthetic process. This protein enables catalytic activity: proton-transporting ATP synthase activity, rotational mechanism. This protein is part of membrane: membrane, and mitochondrial inner membrane. This protein is part of mitochondrion: mitochondrion. This protein is involved in cation transport: ion transport, and ATP synthesis coupled proton transport. This protein enables the following function: proton-transporting ATP synthase activity, rotational mechanism.
MPSSKRTAAIIVAAGRGLRAGAGGPKQYRTIGGRTVISRAMEAFCQHPDVFAVQPVLNPDDLSMFNQAAAQFRYRPPANGGATRQASVRAGLEALAADAPDIVLIHDAARPFVTPALITRAIDAADKAGAAVPAIAVTDTIKQVDESGAVNATPDRAKLRIAQTPQAFHFDMILDAHRRAAREGRDDFTDDAALAEWVGLTVATFEGDAANMKLTTPEDFVREEARLAAALGDIRTGTGYDVHAFGEGDHLMLCGVKVPHNCGFLAHSDGDVGLHALVDAILGALADGDIGSHFPPSDPQWKGAASDKFLKYAVDRVTARGGRVANLEVTMICQQPKIGPLRDQMRARIADITGVAISRIAVKATTSERLGFTGREEGIAATASATIRLPWNDKGRDT	This protein is involved in the following processs: metabolic process, terpenoid biosynthetic process, isoprenoid biosynthetic process, and isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway. This protein is involved in metabolic process: metabolic process. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity, catalytic activity, and lyase activity. This protein enables transferase activity: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity, nucleotidyltransferase activity, cytidylyltransferase activity, and transferase activity. This protein is involved in lipid metabolic process: isoprenoid biosynthetic process, isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway, and terpenoid biosynthetic process. This protein enables the following functions: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity, transferase activity, lyase activity, metal ion binding, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity, cytidylyltransferase activity, nucleotidyltransferase activity, and catalytic activity.
MSAHLIDGKAIAAEIDARAGEVGAKLASSLGRPPCLAVVLVGEDPASDVYVRNKVRRTEAAGLTSIEIRKSAEATEAEIIAIVERLNADDGVDGILVQMPLPGHIDTNRVIGRIDPDKDVDGLTEVSAGRLVLGKPGLRPCTPAGCVLLAERALGDLSGKSVVVIGRSILVGKPAALLFLEKNATVTIAHSRTADLPSLCRTADILVPAVGRPEMVRGDWVKPGACVLDVGINRIDAPERGAGKTRLVGDAAFDEIVGHAGWITPVPGGIGPMTIAMLLKNTVIAAALRAKQPALADF	This protein is involved in the following processs: tetrahydrofolate interconversion, methionine biosynthetic process, histidine biosynthetic process, metabolic process, one-carbon metabolic process, purine nucleotide biosynthetic process, and cellular amino acid biosynthetic process. This protein enables hydrolase activity: methenyltetrahydrofolate cyclohydrolase activity, and hydrolase activity. This protein is involved in metabolic process: one-carbon metabolic process, tetrahydrofolate interconversion, purine nucleotide biosynthetic process, and metabolic process. This protein enables catalytic activity: methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity, oxidoreductase activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, and catalytic activity. This protein is involved in cellular amino acid biosynthetic process: cellular amino acid biosynthetic process, histidine biosynthetic process, and methionine biosynthetic process. This protein enables the following functions: methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, catalytic activity, oxidoreductase activity, methenyltetrahydrofolate cyclohydrolase activity, and hydrolase activity.
MSEAPQARRVGSVDDHSVYDDAKTYYTSEERHNNSRSGPRQRTYSQNSLLGQMERLGLKEPFRRGSHDESNHNRRFLIQVDPTLESLKSQEDTDGNMQITIEDNGPKVLTLRTAGSNGHNRFDIRGTYMLSNLLQELTLAQEYGRKQVILDEARLNENPVNRLSRLIRDHFWDALTRRIDASSIEVAAKDPKDWTDDPRPRIYVPKGAPEQLEYYKKLAADKPDIRLDVVELPETITPEYVVGINKAPGLLAVDMEETVDPKTGERVMSGRPFVVPGGRFNELYGWDSYMESLGLLVNDKVYLAKSMVLNFCFCIKHYGKILNATRSYYLCRSQPPFLTDMALRVYDKIRHEPDATEFLRTAILAAIKEYHSVWVAEPRLDPVTGLSRYRPEGTGVPPETEADHFLHILEPYYKKHNMTFKEFVEAYNFGRIREPELDKYFLHDRAVRESGHDTSYRLEGVCADLATVDLNTLLFKYETDIARTIRNVFGDKLVIPAEYCVGSLQPGQVETSAIWDRRSKRRKLAIDKYLWNEEAGMYFDYDTAKRQQCNYESCTTFWALWAGVASPKQAAIMVTRALPKFEAYGGLLSGTEESRGQIGLDRPNRQWDYPYGWAPQQMLAWTGLYRYSFTEEAERLAYKWLFMITKAFSDFNGVVVEKYDVTRPVDPHRVDAEYGNQGLGFKGVAKEGFGWVNASYIYGLQIINAHMRRALGTLTPYDTFIKALEDNRNRALSEMV	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: trehalose metabolic process, trehalose catabolic process, ascospore formation, metabolic process, and carbohydrate metabolic process. This protein is located in the following component: cytoplasm. This protein enables hydrolase activity: hydrolase activity, alpha,alpha-trehalase activity, and hydrolase activity, acting on glycosyl bonds. This protein is involved in metabolic process: metabolic process. This protein enables metal ion binding: calcium ion binding. This protein enables catalytic activity: catalytic activity. This protein is part of cytoplasm: cytoplasm. This protein is involved in carbohydrate metabolic process: trehalose catabolic process, and trehalose metabolic process. This protein enables the following functions: calcium ion binding, trehalase activity, alpha,alpha-trehalase activity, catalytic activity, hydrolase activity, and hydrolase activity, acting on glycosyl bonds.
MFSWLPFSCALLLLQPLPARSLENAYTAEVGKNAYLPCSYTVPAPGTLVPICWGKGSCPLLQCASVVLRTDETNVTYRKSRRYQLKGNFYKGDMSLTIKNVTLADSGTYCCRIQFPGPMNDEKLELKLSITEPAKVIPAGTAHGDSTTASPRTLTTEGSGSETQTLVTLHDNNGTKISTWADEIKDSGETIRTAVHIGVGVSAGLALALILGVLILKWYSSKKKKLQDLSLITLANSPPGGLVNAGAGRIRSEENIYTIEENIYEMENSNEYYCYVSSQQPS	This protein is part of the following components: immunological synapse, integral component of membrane, early endosome, cell surface, membrane, cell junction, and mediator complex. This protein is involved in the following processs: innate immune response, positive regulation of defense response to bacterium, negative regulation of interferon-alpha production, negative regulation of interleukin-3 production, negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, adaptive immune response, negative regulation of innate immune response, positive regulation of NIK/NF-kappaB signaling, immune system process, negative regulation of type I interferon production, inflammatory response, negative regulation of interleukin-6 production, positive regulation of interleukin-4 production, biological_process, positive regulation of cytokine production, negative regulation of defense response to bacterium, toll-like receptor 7 signaling pathway, natural killer cell tolerance induction, defense response to Gram-positive bacterium, negative regulation of natural killer cell activation, negative regulation of NF-kappaB transcription factor activity, toll-like receptor 3 signaling pathway, negative regulation of gene expression, negative regulation of interleukin-2 production, maternal process involved in female pregnancy, positive regulation of interleukin-1 production, positive regulation of ERK1 and ERK2 cascade, positive regulation of tumor necrosis factor production, negative regulation of interferon-gamma production, negative regulation of granulocyte colony-stimulating factor production, positive regulation of tumor necrosis factor production, macrophage activation involved in immune response, positive regulation of chemokine production, regulation of tolerance induction dependent upon immune response, positive regulation of macrophage activation, negative regulation of T cell proliferation, cellular response to lipopolysaccharide, negative regulation of immunological synapse formation, negative regulation of myeloid dendritic cell activation, negative regulation of immune response to tumor cell, toll-like receptor 9 signaling pathway, positive regulation of T cell proliferation, positive regulation of interferon-gamma production, negative regulation of T-helper 1 type immune response, negative regulation of tumor necrosis factor production, and positive regulation of innate immune response. This protein is located in the following components: membrane, integral component of membrane, cell junction, immunological synapse, cell surface, and early endosome. This protein is involved in signal transduction: toll-like receptor 7 signaling pathway, toll-like receptor 9 signaling pathway, and toll-like receptor 3 signaling pathway. This protein enables metal ion binding: metal ion binding. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in regulation of transcription, DNA-templated: regulation of transcription by RNA polymerase II, and negative regulation of NF-kappaB transcription factor activity. This protein enables the following functions: metal ion binding, and molecular_function.
MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGGPTYYIATNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP	This protein is part of the following components: npBAF complex, NuA4 histone acetyltransferase complex, and nucleus. This protein is involved in the following processs: histone H2A acetylation, histone H4 acetylation, chromatin organization, DNA repair, cellular response to DNA damage stimulus, nervous system development, regulation of growth, and DNA recombination. This protein is located in the following component: nucleus. This protein is involved in metabolic process: histone H2A acetylation, DNA recombination, and histone H4 acetylation. This protein is involved in cellular response to DNA damage stimulus: DNA repair, and cellular response to DNA damage stimulus. This protein is part of nucleus: nucleus.
MATEEHQRLASIVKSCHESLRQLTKEYGATAAWQEHTSPRNAKQLAEYAKAMKQLAAIWETNDGKVELQARSRIKWAIDYITKYFFTEGIYLQKRQREQRLLESYRAEGKLGEVQCRLMEEPPDRLHVLDVGSCFNPFSSAPHLEVTALDLCPATEDVLQADFLKVEVVPGIREPELEEGSVRRLPASHYECVIFSLLLEYMPSAEQRLQCCLQAYDLLLPEGILVLITPDSQHVGKNAHLMKNWRYSLARIGLLRVRFEKLPHISCMVFRKAISRELSQHWASIHREEGMCEEIRIPQDDS	This protein is part of the following components: nucleolus, and cellular_component. This protein is involved in the following processs: rRNA methylation, methylation, and negative regulation of TORC1 signaling. This protein is active in the following components: cellular_component, and nucleolus. This protein enables transferase activity: transferase activity, methyltransferase activity, and rRNA (adenine) methyltransferase activity. This protein is involved in methylation: rRNA methylation, and methylation. This protein enables the following functions: methyltransferase activity, rRNA (adenine) methyltransferase activity, molecular_function, and transferase activity.
MMLAQKQNFMNQFYKKYHYSIQKYQITDLLFFLFLYPFSTSYGNEQFSFDSRFLPSGYNYSLNSNLPPEGEYLVDIYINKIKKESAIIPFYIKGNKLVPCLSKEKLSSLGININNNDNAECAETSKAGISNISFEFSSLRLFIAVPKNLLSEIDKISSKDIDNGIHALFFNYQVNTRLANNKNRYDYISVSPNINYFSWRLRNRFEFNQNNDKKTWERNYTYLEKSFYDKKLNLIVGESYTSSNVYNNYSFTGISVSTDTDMYTPSEIDYTPEIHGVADSDSQIIVRQGNTIIINESVPAGPFSFPITNLMYTGGQLNVEITDIYGNKKQYTVSNSSLPVMRKAGLMVYNFISGKLTKKNSEDGDFFAQGDINYGTHYNSTLFGGYQFSKNYFNLSTGIGTDLGFSGAWLLNVSRSNFKDKNGYNINLQQNTQLRPFNAGVNFDYIYRKKGYVELSGIGWHGNLYNQLKNSFSLSLSKSLDKYGNFSLDYNKIKYWDNAYDSNSMSIRYFFKFMRAMITTNYSLNKYQSYEKKDKRFSINISLPLTKDYGHISSNYSFSNANTGTATSSVGVNGSFFNDARLNWNIQQNRTTRNNGYTDNTSYIATSYASPYGVFTGSYSGSNKYSSQFYSALGGIVLHSDGVAFTQKAGDTSALVRIDNISDIKIGNTPGVYTGYNGFALIPHLQPFKKNTILINDKGIPDDIALANIKKQVIPSRGAIVKVKFDAKKGNNILFKLTTKDGKTPPLGAIAHEKNGKQINTGIVDDDGMLYMSGLSGAGIINVTWNGKVCSFPFSEKDISSKQLSVVNKQCNRPENSGD	This protein is part of the following components: membrane, cell outer membrane, and integral component of membrane. This protein is involved in the following processs: transmembrane transport, and pilus assembly. This protein is located in the following components: integral component of membrane, membrane, and cell outer membrane. This protein is part of membrane: membrane, and cell outer membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in transmembrane transport: transmembrane transport. This protein enables the following function: fimbrial usher porin activity.
MSGQEDWESEIDNPPACVPNLSNSEPAFKASNQNYFSSNNAFNRTTERGFGNRKASDDCNQNFEFSERGFGKQRAGSDANQNFESSERGFGNRRGKGRGGFGTFGKDSNGKQESGDFTNDDNRTIDDNRRRGGFQRRGGFNDETSGRGRRGVRGGTSFSGFGREDGNEQSGFTSNDGFNNETSGFGSGRRGSRGDSSFSGDRESDRGRGFGRGGFRGRNEDIGVESGKGQEGFERSEQGPRVTYIPPPPPAEESDIFKHYQTGINFDKYDDIVVEVSGSDVPPAILTFEEANLCDSLAKNVCKSGYVKLTPIQKHSIPIIVAGRDLMACAQTGSGKTAAFLLPILAHLMVKGVESSAFQTLKEPEAIIVAPTRELINQIYLDARKFSYGTCVRPVVIYGGTQMFHSLKQISEGCNILCATPGRLLDVIRKEKIGLTKLRYLVLDEADRMLDMGFREDIENLLKSSGMPSKEERQTLMFSATFPSSIQSLAREILKPDYLFVVVGQVGGACSDVEQMVIEVDEFGKKDKLMEILQEIGSERTMVFVKTKKKADFIATFLCQEKVPSTSIHGDREQKERETALRDFRTGQCPVIVATSVAARGLDIENVSYVINFDIPDDIDEYVHRIGRTGRCGNTGRAISFFDKRGDDEQRIARSLVKVLSDAHQEVPAWLEEVAFSAHGSSAYNPRSNKFASTDDRKRGDSRGDYSTSGFSPSAAQAEEEDWG	This protein is part of the following components: pi-body, piP-body, and cytoplasm. This protein is involved in the following processs: male meiotic nuclear division, multicellular organism development, piRNA metabolic process, gene silencing by RNA, DNA methylation involved in gamete generation, male meiosis I, negative regulation of transposition, cell differentiation, oogenesis, piRNA biosynthetic process, meiotic cell cycle, and spermatogenesis. This protein is located in the following components: cytoplasm, pi-body, and piP-body. This protein enables hydrolase activity: hydrolase activity, and ATP hydrolysis activity. This protein is involved in metabolic process: piRNA metabolic process, and piRNA biosynthetic process. This protein enables catalytic activity: helicase activity, and RNA helicase activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of cytoplasm: cytoplasm. This protein is involved in methylation: DNA methylation involved in gamete generation. This protein is involved in cell cycle: meiotic cell cycle. This protein enables the following functions: ATP hydrolysis activity, RNA helicase activity, ATP binding, nucleotide binding, hydrolase activity, helicase activity, and nucleic acid binding.
MHTHNNFKTPSDEDELDDLDEDMVVGVIAEIEQEVLNESDSDNDEYDLVEMGAPVPDNDGDSSYDGNESISSDDSFDPNAADSDSDDSMLDDAGDDASAGGATSSKRRKDDDNPSGSNRQSEATFDLDEDDETDETVRAMIAAIKKPRSAPPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEYDNEANKLLRTIEVHSKACRDVEFTEDGRFLLTCSKDKCVMVTDMETEKLKKLYETAHDDAINTLHVLNENLFATGDDAGTVKLWDLRTKNAIFELKELEDQITQLTTNDQSKLLLATSADGYLTTFNIAARKMYVQSEPYEEELSCMGIYRGDSKLVVGTSKGRLYTYNWGQFGYHCDMYPGIKSPISLMIPITDRIACVAGEDGNIRACHIAPYRNLGVVGQHNMPIESLDVNSNGELIASSSHNNDVRFWNVKYFEDFGDIKYNEKHNAYKEQRHNLPSSKCSNASDFFADLTKEDADDDDAGAGPSNMA	This protein is part of the following component: cellular_component. This protein is involved in the following processs: biological_process, and defense response to Gram-negative bacterium. This protein is active in the following component: cellular_component. This protein enables the following function: molecular_function.
MTLESPSTRLMTCQSSLLPEKPRFLSQKMWAPHLVVAYLIFVTLALALPGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPVGIIAGATIGAGILVVFSFAALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTASISTATRVMKAIYSSFKDDVDLKQDLRCDTIDTREEYEMKDPTNGYYNVRAHEDRPSSRAVLYADYRAPGPTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTPYEAYDPIGKYATATRFSYTSQHSDYGQRFQQRMQTHV	This protein is part of the following components: membrane, plasma membrane, cell projection membrane, cell-cell junction, dendritic shaft, integral component of membrane, integral component of plasma membrane, perinuclear region of cytoplasm, and membrane raft. This protein is involved in the following process: cell-cell adhesion. This protein acts upstream of or within the following processs: cell-cell adhesion, excretion, positive regulation of actin filament polymerization, and negative regulation of protein phosphorylation. This protein is active in the following components: cell-cell junction, and integral component of plasma membrane. This protein is located in the following components: cell-cell junction, integral component of membrane, perinuclear region of cytoplasm, plasma membrane, membrane, dendritic shaft, cell projection membrane, and membrane raft. This protein is part of membrane: cell projection membrane, plasma membrane, membrane raft, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables the following functions: myosin binding, protein binding, and cell adhesion molecule binding.
MGTSIVNLNQKIELPPIQVLFESLNRENETKPHFEERRLYQPNPSFVPRTNIAVGSPVNPVPVSSPVFFIGPSPQRSIQNHNAIMTQNIRQYPVIYNNNREVISTGERNYIITVGGPPVTSSQPEYEHISTPNFYQEQRLAQPHPVNESMMIGGYTNPQPISISRGKMLSGNISTNSVRGSNNGYSAKEKKHKAHGKRSNLPKATVSILNKWLHEHVNNPYPTVQEKRELLAKTGLTKLQISNWFINARRRKIFSGQNDANNFRRKFSSSTNLAKF	This protein is part of the following components: nucleus, and chromatin. This protein is involved in the following processs: biological_process, regulation of transcription, DNA-templated, and regulation of transcription by RNA polymerase II. This protein is located in the following components: chromatin, and nucleus. This protein enables DNA binding: DNA binding, and RNA polymerase II cis-regulatory region sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: regulation of transcription, DNA-templated, and regulation of transcription by RNA polymerase II. This protein enables the following functions: chromatin binding, DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, and DNA-binding transcription factor activity, RNA polymerase II-specific.
MRVIIAGGGTGGHLFPGIALAESLIGKYPEAQIIFVGTPKGLEAKVIPKTGYELSFISIQGFVGKSFSEKAKSLKSLLKSMFESKNIINSFAPDIVFGVGGYASFPVVLAAFLKKIPTIILEQNTVPGLANKLLGKIASAVAITYPETIEYFSREKTYLTGTPIRKKILEGNKEKAKKLFDIEEGRITILILGGSLGARKINKAMTEGLSYLLPLKNRIQIIHQTGEADYNWVYNEYRNLSFRATVLPFIYDMVEAYSVADLVISRAGASTVAELTAIGKASILIPYPYAAYNHQEMNARRLLSRGACELILDRELNGEVLAKKINKILNKPEIMKEMEMASLAFGKPYAGEKIIEIAESLLRRKR	This protein is part of the following components: plasma membrane, and membrane. This protein is involved in the following processs: cell wall organization, lipid glycosylation, cell cycle, cell division, peptidoglycan biosynthetic process, carbohydrate metabolic process, and regulation of cell shape. This protein is located in the following components: membrane, and plasma membrane. This protein is involved in metabolic process: peptidoglycan biosynthetic process. This protein is part of membrane: plasma membrane, and membrane. This protein enables transferase activity: transferase activity, UDP-N-acetyl-D-glucosamine, glycosyltransferase activity, hexosyltransferase activity, and undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity. This protein is involved in lipid metabolic process: lipid glycosylation. This protein is involved in carbohydrate metabolic process: carbohydrate metabolic process. This protein is involved in cell cycle: cell cycle. This protein is involved in cell division: cell division. This protein enables the following functions: UDP-N-acetyl-D-glucosamine, transferase activity, glycosyltransferase activity, hexosyltransferase activity, and undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity.
MRVKEIRKNYQHLWRWGIMLRWGTMLLGMLMICSAAEQLWVTVYYGVPVWKEATTTLFCASDAKAYDTEAHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNNMVEQMHENIISLWDQSLKPCVKLTPLCVTLHCTDLRNTTNNNSSIEEKMKGEIKNCSFNVTTNIRDKVQKEYALFYKLDVVPIDNDNNSTNTCYRLISCDTSVITQACPKVSFEPIPIHYCTPAGFALLKCNNKTFNGTGPCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEGVVIRSENFTDNVKTIIVQLNETVKINCIRPNNKTRKRVTMGPGRVYYTTGEIIGDIRQAHCNISRAEWNKTLEQIANKLRKQFENKTIVFNQSSGGDPEIVMHNFNCGGEFFYCDSSQLFNSTHLSNGTWWNGTGPENITLPCRIKQIVNMWQEVGKAMYAPPIRGQIRCSSNITGLLLTRDGGNTQNNNTNSSIEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRAKRRVVQREKRAVGIGAVFLGFLGAAGSTMGAAAVTLTVQARQLLPGIVQQQNNLLRAIDAQQHLLQLTVWGIKQLQARVLAVERYLKDQQLMGIWGCSGKFICTTAVPWNTSWSNKSFNEIWDNMTWMEWEREINNYTNLIYNLIEESQNQQEKNEQDLLALDKWDSLWNWFSITKWLWYIKIFIMIVGGLVGLRIVFTVLSIVNRVRQGYSPLSFQTRLPARGPDRPEGIEEEGGERDRDRSGPLVDGLLALIWVDLRSLCLFSYHRLRDLLLIVTRTVELLGRKGWEVLKYLWNLLQYWSQELKNSAVSLLNATAIAVAEGTDRVIEILQRTYRAILHIPVKIRQGLERALL	This protein is part of the following components: viral envelope, virion component, host cell membrane, host cell plasma membrane, host cell endosome, virion membrane, integral component of membrane, host cell endosome membrane, and membrane. This protein is involved in the following processs: positive regulation of receptor clustering, virion attachment to host cell, viral protein processing, mitigation of host immune response by virus, positive regulation of establishment of T cell polarity, membrane fusion involved in viral entry into host cell, positive regulation of plasma membrane raft polarization, endocytosis involved in viral entry into host cell, fusion of virus membrane with host plasma membrane, clathrin-dependent endocytosis of virus by host cell, stimulatory C-type lectin receptor signaling pathway, fusion of virus membrane with host endosome membrane, viral entry into host cell, viral process, and actin filament reorganization. This protein is located in the following components: virion membrane, viral envelope, host cell membrane, integral component of membrane, membrane, host cell plasma membrane, host cell endosome, and host cell endosome membrane. This protein is involved in signal transduction: stimulatory C-type lectin receptor signaling pathway. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables the following function: structural molecule activity.
MFVARSIAADHKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSESGDWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGESNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGIVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSSSRAHSPMIAVGSDDSSPNAMAKVQIFEYNENTRKYAKAETLMTVTDPVHDIAFAPNLGRSFHILAIATKDVRIFTLKPVRKELTSSGGPTKFEIHIVAQFDNHNSQVWRVSWNITGTVLASSGDDGCVRLWKANYMDNWKCTGILKGNGSPVNGSSQQGTSNPSLGSTIPSLQNSLNGSSAGRKHS	This protein is part of the following components: host cell, chromosome, lysosomal membrane, kinetochore, Seh1-associated complex, nucleus, kinetochore, membrane, nuclear pore, cytosol, nuclear pore outer ring, chromosome, centromeric region, nuclear envelope, GATOR2 complex, and lysosome. This protein is involved in the following processs: mitotic spindle organization, mitotic metaphase plate congression, cytokine production involved in inflammatory response, positive regulation of TOR signaling, mitotic nuclear membrane reassembly, nuclear pore organization, cellular response to amino acid starvation, tRNA export from nucleus, viral life cycle, regulation of cellular response to heat, cell cycle, regulation of glycolytic process, cellular protein-containing complex localization, viral transcription, positive regulation of TORC1 signaling, mRNA export from nucleus, cell division, regulation of gene silencing by miRNA, attachment of mitotic spindle microtubules to kinetochore, protein sumoylation, protein transport, viral process, defense response to Gram-positive bacterium, intracellular transport of virus, mRNA transport, and chromosome segregation. This protein colocalizes with the following component: kinetochore. This protein is located in the following components: nuclear envelope, lysosomal membrane, host cell, chromosome, centromeric region, cytosol, chromosome, nucleus, lysosome, membrane, and kinetochore. This protein is involved in metabolic process: cytokine production involved in inflammatory response, and protein sumoylation. This protein is part of membrane: membrane, and lysosomal membrane. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in cell cycle: cell cycle. This protein is involved in cell division: cell division. This protein is involved in protein transport: protein transport. This protein enables the following functions: protein binding, and structural molecule activity.
MLSLILTIFFVHVAIYLVNTVGATTIDTLLWILYLKLPTSTSKNAREQSRLKREVVQLKREMNNTSSQDEFAKWAKLRRKHDKAMDEYEAMNKKLTAQKTSFDWSVKIARWLSTNGLKIFLQFYYSKTPVFALPAGWFPSYVEWVLSFPRAPRGSVSVQVWNSVCATAIAVMAEIVTSMLLQLRSRSASPASTAKAQKAQ	This protein is part of the following components: endoplasmic reticulum membrane, integral component of membrane, endoplasmic reticulum, membrane, and GET complex. This protein is involved in the following processs: tail-anchored membrane protein insertion into ER membrane, and protein insertion into ER membrane. This protein is located in the following components: integral component of membrane, membrane, endoplasmic reticulum membrane, and endoplasmic reticulum. This protein is part of membrane: membrane, and endoplasmic reticulum membrane. This protein is part of integral component of membrane: integral component of membrane.
MELRSWLLWVVAAAGAVVLLAADAQGQKIFTNTWAVHIPGGPAVADRVAQKHGFHNLGQIFGDYYHFWHRAVTKRSLSPHRPRHSRLQREPQVKWLEQQVAKRRAKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNADDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIVEILVEPKDIGKRLEVRKAVTACLGEPNHITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPAGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLSTPPESSGCKTLTSSQACVVCEEGYSLHQKSCVQHCPPGFIPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCLSCPSHASLDPVEQTCSRQSQSSRESRPQQQPPALRPEVEMEPRLQAGLASHLPEVLAGLSCLIIVLIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL	This protein is part of the following components: cell surface, Golgi cisterna, trans-Golgi network transport vesicle membrane, membrane raft, early endosome, membrane, endoplasmic reticulum membrane, endoplasmic reticulum, extracellular region, endosome, Golgi membrane, trans-Golgi network transport vesicle, Golgi apparatus, endosome membrane, integral component of Golgi membrane, plasma membrane, trans-Golgi network, endoplasmic reticulum lumen, and integral component of membrane. This protein is involved in the following processs: blastocyst formation, negative regulation of low-density lipoprotein particle receptor catabolic process, positive regulation of transforming growth factor beta1 activation, zymogen activation, peptide hormone processing, signal peptide processing, negative regulation of endopeptidase activity, zymogen inhibition, regulation of protein catabolic process, viral life cycle, secretion by cell, proteolysis, nerve growth factor production, peptide biosynthetic process, negative regulation of transforming growth factor beta1 production, protein processing, regulation of endopeptidase activity, and dibasic protein processing. This protein acts upstream of or within the following processs: protein processing, secretion by cell, positive regulation of cell migration, negative regulation of transforming growth factor beta1 production, regulation of cholesterol transport, peptide biosynthetic process, peptide hormone processing, nerve growth factor production, zymogen activation, regulation of endopeptidase activity, signal peptide processing, positive regulation of transforming growth factor beta1 activation, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of protein catabolic process, negative regulation of low-density lipoprotein particle receptor catabolic process, regulation of signal transduction, zymogen inhibition, and dibasic protein processing. This protein is active in the following components: trans-Golgi network, membrane, and integral component of Golgi membrane. This protein is located in the following components: endosome, trans-Golgi network transport vesicle, plasma membrane, endoplasmic reticulum lumen, membrane raft, Golgi cisterna, trans-Golgi network, Golgi apparatus, cell surface, endoplasmic reticulum membrane, endoplasmic reticulum, endosome membrane, Golgi membrane, trans-Golgi network transport vesicle membrane, membrane, early endosome, integral component of membrane, and extracellular region. This protein enables hydrolase activity: endopeptidase activity, serine-type peptidase activity, hydrolase activity, peptidase activity, and serine-type endopeptidase activity. This protein is involved in metabolic process: peptide biosynthetic process. This protein enables metal ion binding: metal ion binding. This protein is part of membrane: endosome membrane, membrane, plasma membrane, trans-Golgi network transport vesicle membrane, endoplasmic reticulum membrane, Golgi membrane, and membrane raft. This protein is part of integral component of membrane: integral component of membrane, and integral component of Golgi membrane. This protein is part of extracellular region: extracellular region. This protein is involved in proteolysis: proteolysis, dibasic protein processing, signal peptide processing, peptide hormone processing, protein processing, and zymogen activation. This protein enables the following functions: serine-type peptidase activity, endopeptidase activity, nerve growth factor binding, protease binding, serine-type endopeptidase activity, peptidase activity, hydrolase activity, metal ion binding, peptide binding, serine-type endopeptidase inhibitor activity, and protein binding.
MAPTQNLFLVAIAFAVIFTASTVHGRHNGAEDIVHSSCEHASYPSLCVRTLSSYSGPTITNRRDLAQAAIKISLSHAQSAAKKLAVVRDSVGKKKQEKAALVDCVEMIGDSVDELSRTLGVLKHLRVSGGSAKEFRWQMSNAQTWASAALTDDDTCLDGFQGMDDGEIKTEVKQWMTKVARVTSNALYMVNQLDETRGKPHDVHL	This protein is part of the following components: apoplast, and extracellular region. This protein is involved in the following processs: negative regulation of catalytic activity, and regulation of shoot apical meristem development. This protein is located in the following components: apoplast, and extracellular region. This protein is part of extracellular region: extracellular region, and apoplast. This protein enables the following function: enzyme inhibitor activity.
MASINLNIIMAFIMALMGVLIYRSHLMSTLLCLEGMMLSLFILVTLLISQSHMLTTSMMPLILLVFSACEAGVGLALLVTISTTYGNDHVQNLNLLQC	This protein is part of the following components: mitochondrial membrane, respirasome, integral component of membrane, membrane, and mitochondrion. This protein is involved in the following process: ATP synthesis coupled electron transport. This protein is located in the following components: mitochondrion, membrane, mitochondrial inner membrane, respirasome, integral component of membrane, and mitochondrial membrane. This protein is involved in metabolic process: ATP synthesis coupled electron transport. This protein enables catalytic activity: oxidoreductase activity, acting on NAD(P)H, and NADH dehydrogenase (ubiquinone) activity. This protein is part of membrane: mitochondrial membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of mitochondrion: mitochondrion. This protein enables the following functions: NADH dehydrogenase (ubiquinone) activity, and oxidoreductase activity, acting on NAD(P)H.
MYRALRLLARSRRLLRVPSAGAAVSGEATTLPRCAPNVARMASQNSFRVEFDTFGELKVPTDKYYGAQTVRSTMNFKIGGATERMPIPVIQAFGILKRAAAEVNQEYGLDPKIASAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAAVEVHKVLLPGLQKLHDALSAKSKEFAQVIKIGRTHTQDAVPLTLGQEFSGYVQQVQYAMVRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTAACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTDNCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK	This protein is part of the following components: nucleus, site of double-strand break, cytoplasm, mitochondrion, tricarboxylic acid cycle enzyme complex, chromosome, and cytosol. This protein is involved in the following processs: fumarate metabolic process, positive regulation of cold-induced thermogenesis, positive regulation of double-strand break repair via nonhomologous end joining, malate metabolic process, tricarboxylic acid cycle, cellular response to DNA damage stimulus, DNA repair, and negative regulation of histone H3-K36 methylation. This protein acts upstream of or within the following processs: cellular response to DNA damage stimulus, positive regulation of double-strand break repair via nonhomologous end joining, negative regulation of histone H3-K36 methylation, tricarboxylic acid cycle, homeostasis of number of cells within a tissue, fumarate metabolic process, and malate metabolic process. This protein is active in the following component: mitochondrion. This protein is located in the following components: chromosome, mitochondrion, cytosol, nucleus, site of double-strand break, and cytoplasm. This protein is involved in metabolic process: malate metabolic process, tricarboxylic acid cycle, and fumarate metabolic process. This protein enables catalytic activity: lyase activity, fumarate hydratase activity, and catalytic activity. This protein is involved in cellular response to DNA damage stimulus: cellular response to DNA damage stimulus, and DNA repair. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein enables the following functions: catalytic activity, lyase activity, histone binding, and fumarate hydratase activity.
MTQIHQINDIDVHRITSGQVITDLTTAVKELVDNSIDANANQIEIIFKDYGLESIECSDNGDGIDPSNYEFLALKHYTSKIAKFQDVAKVQTLGFRGEALSSLCGIAKLSVITTTSPPKADKLEYDMVGHITSKTTTSRNKGTTVLVSQLFHNLPVRQKEFSKTFKRQFTKCLTVIQGYAIINAAIKFSVWNITPKGKKNLILSTMRNSSMRKNISSVFGAGGMRGLEEVDLVLDLNPFKNRMLGKYTDDPDFLDLDYKIRVKGYISQNSFGCGRNSKDRQFIYVNKRPVEYSTLLKCCNEVYKTFNNVQFPAVFLNLELPMSLIDVNVTPDKRVILLHNERAVIDIFKTTLSDYYNRQELALPKRMCSQSEQQAQKRLKTEVFDDRSTTHESDNENYHTARSESNQSNHAHFNSTTGVIDKSNGTELTSVMDGNYTNVTDVIGSECEVSVDSSVVLDEGNSSTPTKKLPSIKTDSQNLSDLNLNNFSNPEFQNITSPDKARSLEKVVEEPVYFDIDGEKFQEKAVLSQADGLVFVDNECHEHTNDCCHQERRGSTDTEQDDEADSIYAEIEPVEINVRTPLKNSRKSISKDNYRSLSDGLTHRKFEDEILEYNLSTKNFKEISKNGKQMSSIISKRKSEAQENIIKNKDELEDFEQGEKYLTLTVSKNDFKKMEVVGQFNLGFIIVTRKVDNKYDLFIVDQHASDEKYNFETLQAVTVFKSQKLIIPQPVELSVIDELVVLDNLPVFEKNGFKLKIDEEEEFGSRVKLLSLPTSKQTLFDLGDFNELIHLIKEDGGLRRDNIRCSKIRSMFAMRACRSSIMIGKPLNKKTMTRVVHNLSELDKPWNCPHGRPTMRHLMELRDWSSFSKDYEI	This protein is part of the following components: mismatch repair complex, cytoplasm, MutLalpha complex, and nucleus. This protein is involved in the following processs: cellular response to DNA damage stimulus, DNA repair, mismatch repair, and meiotic mismatch repair. This protein contributes to the following functions: single-stranded DNA binding, double-stranded DNA binding, dinucleotide insertion or deletion binding, heteroduplex DNA loop binding, and DNA insertion or deletion binding. This protein is located in the following components: cytoplasm, and nucleus. This protein enables hydrolase activity: ATP hydrolysis activity. This protein enables nucleotide binding: ATP binding. This protein is involved in cellular response to DNA damage stimulus: cellular response to DNA damage stimulus, DNA repair, meiotic mismatch repair, and mismatch repair. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: single-stranded DNA binding, dinucleotide insertion or deletion binding, mismatched DNA binding, heteroduplex DNA loop binding, DNA insertion or deletion binding, and double-stranded DNA binding. This protein is part of nucleus: nucleus. This protein enables the following functions: ATP binding, ATP hydrolysis activity, protein binding, and mismatched DNA binding.
MMASLFSVFDPTSSFLSNWLSMLIPLLFMVMSFWLIPSRPQFLAKSVLMGLNREMSLLMGPASFGANILVIALFLFILFNNFIGLFPYIFTATSHLAVTLSLAVPLWISFILYTWIKETTNALAHLVPLGTPAPLMPFMVLMEIISNMIRPITLSVRLAANMIAGHLLLTLLGAQGTLENLYVTSIVVFSQIILLMLEFSVAIIQSYVFMTLMTLYASE	This protein is part of the following components: integral component of membrane, mitochondrion, proton-transporting ATP synthase complex, coupling factor F(o), mitochondrial inner membrane, and membrane. This protein is involved in the following processs: ATP biosynthetic process, ion transport, and ATP synthesis coupled proton transport. This protein is located in the following components: mitochondrion, mitochondrial inner membrane, membrane, and integral component of membrane. This protein is involved in metabolic process: ATP biosynthetic process. This protein is part of membrane: membrane, and mitochondrial inner membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of mitochondrion: mitochondrion. This protein is involved in cation transport: ion transport, and ATP synthesis coupled proton transport. This protein enables the following function: proton transmembrane transporter activity.
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTIYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF	This protein is part of the following components: cytoskeleton, protein-containing complex, focal adhesion, nucleus, actin cytoskeleton, plasma membrane, cytoplasm, and dense body. This protein is located in the following components: focal adhesion, plasma membrane, dense body, nucleus, cytoplasm, actin cytoskeleton, and cytoskeleton. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of membrane: plasma membrane. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables the following functions: nucleotide binding, and ATP binding.
MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKKKRGVDYNAEIPFEKKPALGFYDTSEENYQTLDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPASQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSHGSEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNAEHIAYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAYLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLKAKF	This protein is part of the following components: nuclear speck, spliceosomal complex, nucleoplasm, U2-type catalytic step 2 spliceosome, cytoplasm, Prp19 complex, nucleus, DNA replication factor A complex, and catalytic step 2 spliceosome. This protein is involved in the following processs: DNA repair, cell cycle, mRNA splicing, via spliceosome, RNA splicing, positive regulation of transcription by RNA polymerase II, DNA damage checkpoint signaling, cellular response to DNA damage stimulus, mRNA processing, DNA damage checkpoint signaling, and regulation of transcription by RNA polymerase II. This protein colocalizes with the following component: DNA replication factor A complex. This protein is located in the following components: nucleoplasm, nuclear speck, nucleus, and cytoplasm. This protein is involved in metabolic process: mRNA processing, RNA splicing, and mRNA splicing, via spliceosome. This protein is involved in cellular response to DNA damage stimulus: DNA repair, and cellular response to DNA damage stimulus. This protein enables RNA binding: RNA binding. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: RNA polymerase II transcription regulatory region sequence-specific DNA binding, and DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: positive regulation of transcription by RNA polymerase II. This protein is involved in cell cycle: cell cycle. This protein enables the following functions: RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA binding, WD40-repeat domain binding, RNA binding, and DNA-binding transcription activator activity, RNA polymerase II-specific.
MIQVEENEHIQTLVYQLNKEGKSICGDSFFMKADDKELICAVADGLGSGSLANESSAAIKDLVENYASEDVESIIERCNQAMKNKRGATASILKINFEQRQFTYCSVGNVRFILHSPSGESFYPLPISGYLSGKPQKYKTHTATYEKGSKFIIHTDGLNVPDIRSHLKKGQSVEEISNSLKMYTTSRKDDLTYILGQLS	This protein is involved in the following processs: response to heat, protein dephosphorylation, and dephosphorylation. This protein enables hydrolase activity: hydrolase activity, and phosphoprotein phosphatase activity. This protein is involved in metabolic process: protein dephosphorylation, and dephosphorylation. This protein enables catalytic activity: catalytic activity. This protein enables the following functions: L-phosphoserine phosphatase activity, hydrolase activity, phosphoserine phosphatase activity, D-phosphoserine phosphatase activity, phosphoprotein phosphatase activity, phosphatase activity, and catalytic activity.
MKNWGSSDSGGSEDPPQEDSCLDPLDGDPNSRPVPAKPHIFPTAKSRSRLFGKCDSEEASMDCSYEEGQLASCPAITVSPVVMIPKHEDGPTCARQPSQDSVTAGSEKSLKLYDRRKIFEAVAQNNCEELQSLLLFLQKSKKHLMDSEFKDPETGKTCLLKAMLNLHDGQNDTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILILGAKLHPTLKLEGLTNKKGLTPLALAARSGKIGVLAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFIYCLYMIIFTTAAYYRPVDGLPPYKLKHTVGDYFRVTGEILSVLGGVYFFFRGIQYFLQRRPSLKTLFVDSYSEMLFFVQSLFMLGTVVLYFCHHKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIEDGKNNSVPTESTLHRWRGPGCRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGIKRTLSFSLRSGRVSGRNWKNFSLVPLLRDASTRERHPAQPEEVHLRHFAGSLKPEDAEIFKDPVGLGEK	This protein is part of the following components: membrane, neuron projection, dendritic spine membrane, plasma membrane, cell projection, intrinsic component of plasma membrane, integral component of plasma membrane, synapse, cell junction, integral component of membrane, and postsynaptic membrane. This protein is involved in the following processs: response to heat, cellular response to heat, cellular response to acidic pH, cellular response to ATP, response to organonitrogen compound, detection of temperature stimulus involved in thermoception, ion transmembrane transport, peptide secretion, ion transport, detection of chemical stimulus involved in sensory perception of pain, transmembrane transport, protein homotetramerization, sensory perception of mechanical stimulus, excitatory postsynaptic potential, cellular response to alkaloid, sensory perception of pain, urinary bladder smooth muscle contraction, behavioral response to pain, response to capsazepine, calcium ion transmembrane transport, temperature homeostasis, negative regulation of transcription by RNA polymerase II, diet induced thermogenesis, fever generation, calcium ion import across plasma membrane, smooth muscle contraction involved in micturition, calcium ion transport, detection of temperature stimulus involved in sensory perception of pain, response to pH, thermoception, release of sequestered calcium ion into cytosol, response to pain, and lipid metabolic process. This protein is located in the following components: plasma membrane, cell junction, cell projection, membrane, integral component of membrane, neuron projection, integral component of plasma membrane, intrinsic component of plasma membrane, synapse, dendritic spine membrane, and postsynaptic membrane. This protein is involved in metabolic process: diet induced thermogenesis. This protein enables metal ion binding: metal ion binding. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of membrane: postsynaptic membrane, membrane, plasma membrane, and dendritic spine membrane. This protein is part of integral component of membrane: integral component of membrane, and integral component of plasma membrane. This protein is involved in lipid metabolic process: lipid metabolic process. This protein is involved in transmembrane transport: transmembrane transport. This protein is involved in regulation of transcription, DNA-templated: negative regulation of transcription by RNA polymerase II. This protein is involved in cation transport: release of sequestered calcium ion into cytosol, ion transmembrane transport, calcium ion transport, ion transport, calcium ion import across plasma membrane, and calcium ion transmembrane transport. This protein enables the following functions: metal ion binding, phosphoprotein binding, calmodulin binding, excitatory extracellular ligand-gated ion channel activity, calcium-release channel activity, extracellular ligand-gated ion channel activity, calcium channel activity, nucleotide binding, transmembrane signaling receptor activity, ATP binding, ion channel activity, phosphatidylinositol binding, and temperature-gated ion channel activity.
MSNNDLLNYYHRANELVFKGLIEFSCMKAAIELDLFSHMAEGPKDLATLAADTGSVPPRLEMLLETLRQMRVINLEDGKWSLTEFADYMFSPTPKEPNLHQTPVAKAMAFLADDFYMGLSQAVRGQKNFKGQVPYPPVTREDNLYFEEIHRSNAKFAIQLLLEEAKLDGVKKMIDVGGGIGDISAAMLKHFPELDSTILNLPGAIDLVNENAAEKGVADRMRGIAVDIYKESYPEADAVLFCRILYSANEQLSTIMCKKAFDAMRSGGRLLILDMVIDDPENPNFDYLSHYILGAGMPFSVLGFKEQARYKEILESLGYKDVTMVRKYDHLLVQAVKP	This protein is involved in the following processs: methylation, light-dependent bacteriochlorophyll biosynthetic process, light-independent bacteriochlorophyll biosynthetic process, bacteriochlorophyll biosynthetic process, and chlorophyll biosynthetic process. This protein is involved in metabolic process: bacteriochlorophyll biosynthetic process, light-dependent bacteriochlorophyll biosynthetic process, chlorophyll biosynthetic process, and light-independent bacteriochlorophyll biosynthetic process. This protein enables metal ion binding: metal ion binding. This protein enables transferase activity: methyltransferase activity, O-methyltransferase activity, and transferase activity. This protein is involved in methylation: methylation. This protein enables the following functions: metal ion binding, methyltransferase activity, transferase activity, and O-methyltransferase activity.
MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEMGQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVILETIMLQTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACKWSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPNRLKKIRNWRANQAARKPKVDGQVSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNLSMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHSGLHHRPDKISDHSSVKQEYTHKAGSSKHHGPISTTPGIIPQKMSLDKYREKRKLETLDLDVRDHYIAAQVEQQHKQGQSQAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVSSSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHSADGIPPTVLRSPVGLSSDGISSSSSSSRKRLHVNDASHNHHSKMSKSSKSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKPVETNGPDANHEYSTSSQHMDYKDTFDMLDSLLSAQGMNM	This protein is part of the following components: nucleus, plasma membrane, host cell nucleus, nucleoplasm, cytoplasm, cyclin/CDK positive transcription elongation factor complex, perinuclear region of cytoplasm, and cytosol. This protein is involved in the following processs: transcription, DNA-templated, regulation of cyclin-dependent protein serine/threonine kinase activity, viral process, positive regulation of DNA-templated transcription, elongation, regulation of transcription by RNA polymerase II, late viral transcription, snRNA transcription by RNA polymerase II, early viral transcription, transcription by RNA polymerase II, cell division, skeletal muscle tissue development, positive regulation of cyclin-dependent protein serine/threonine kinase activity, positive regulation of transcription by RNA polymerase II, transcription elongation from RNA polymerase II promoter, and cell cycle. This protein is active in the following component: nucleus. This protein is located in the following components: cytoplasm, cytosol, plasma membrane, nucleoplasm, perinuclear region of cytoplasm, and nucleus. This protein is involved in metabolic process: snRNA transcription by RNA polymerase II, transcription by RNA polymerase II, transcription elongation from RNA polymerase II promoter, and transcription, DNA-templated. This protein is part of membrane: plasma membrane. This protein enables RNA binding: 7SK snRNA binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in regulation of transcription, DNA-templated: regulation of transcription by RNA polymerase II, positive regulation of transcription by RNA polymerase II, and positive regulation of DNA-templated transcription, elongation. This protein is involved in cell cycle: cell cycle. This protein is involved in cell division: cell division. This protein enables the following functions: RNA polymerase binding, chromatin binding, cyclin-dependent protein serine/threonine kinase regulator activity, 7SK snRNA binding, cyclin-dependent protein serine/threonine kinase activator activity, transcription coactivator binding, and protein binding.
MALKKFNPVTPSTRQLVIVDRSGLYKGKPVKGLTEGLTKSGGRNNYGRITARFIGGGHKRSYRIIDFKRRKFDVVGTVERIEYDPNRTAFIALIKYDDGELSYIIAPQRLAAGDKIVAGEAVDVKPGNAMPLASMPVGTIVHNIELKPGKGGQVARSAGGYAQLVGRDQGMAILRLNSGEQRVVHGSCMATVGAVSNPDHGNINDGKAGRTVWRGKRPHNRGVTMNPVDHPHGGGEGRTSGGRHPVSPWGKPTKGKKTRSNKATDKFILRSRHQRKS	This protein is part of the following components: ribosome, and large ribosomal subunit. This protein is involved in the following process: translation. This protein is located in the following component: ribosome. This protein enables RNA binding: RNA binding, and rRNA binding. This protein enables transferase activity: transferase activity. This protein is involved in translation: translation. This protein enables structural constituent of ribosome: structural constituent of ribosome. This protein is part of ribosome: ribosome. This protein enables the following functions: structural constituent of ribosome, RNA binding, rRNA binding, and transferase activity.
MGDGLTPEGKAQLITRNLQEVLGEDKMKEILKERPLRIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWDLLELRTRYYEQVIQAMLQSIGVPLERLRFIRGTEFQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPALGYAKRIHLMNPMVPGLTGAKMSSSEEESKIDLLDSPADVKKKLKKAFCEPGNIENNGVLSFVRHVLFPLKSEFVVLRDEKFGGNKTYTDFETLEKDFTEQLVHPGDLKASVEKALNKLLDPIREKFNSPEMKKLSNDAYPGASKQKTVPKGSTKNSGPEEIDPSLLDLRVGKILSVRQHPDADSLYVESVDVGEENPRCVVSGLVQYVPSDQLLGRSVVLLCNLKPQKMRGIESQGMLLCASTEGEQKQVEPLDPPTGSAPGERIYIEGYENGEPEGELKPKKKVFEKLQVDFRISDDLCAQWKGKNFLTKLGSVTCKTLRGGSIS	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: translation, tyrosyl-tRNA aminoacylation, and tRNA aminoacylation for protein translation. This protein is located in the following component: cytoplasm. This protein is involved in metabolic process: tyrosyl-tRNA aminoacylation, and tRNA aminoacylation for protein translation. This protein enables catalytic activity: tyrosine-tRNA ligase activity, ligase activity, and aminoacyl-tRNA ligase activity. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein enables RNA binding: tRNA binding, and RNA binding. This protein is part of cytoplasm: cytoplasm. This protein is involved in translation: translation. This protein enables the following functions: tyrosine-tRNA ligase activity, nucleotide binding, aminoacyl-tRNA ligase activity, ligase activity, tRNA binding, ATP binding, and RNA binding.
MKLHSSSKIQNHAWLSDARMNNPSETSKSPESGDGNTGTQTNGLDFQKQAVPIGAITSAQAQALLGHLHQVQLAGTSLQAAAHSLNVQTKFKEEPGEPMQVVQPSQQPSLQAAIPQTQLMVAGGQIAGLTLTPAQQQMLLQQAQAQLLAAAVQHSASQQHNAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQYVLVHPTTNLQSAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPVQQLPQSQTTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENITSDSTLTNQSVLNSPGHGMEGLNRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGSSSSPIKSLFSSPNPLVASTPSLVTSSPATTLTVNPVLPLTSAAAITSFHIPGTTGTSSANTATVISTAPPVSSVLTSPSLSSSPSATAASSEASTAGETSTTQTTSTPMTSSLNTGQVMVTASGIHTAAATALQGAAQLPTNASLAAMAAAAGLNPGLMAPSQFAAGGALFSLNPGALGSALSPALMSNSTLATIQALASSGSLPITSLDAAGNLVFANAGGTPNIVTAPLFLNPQNLSLFTSNPVSLISAASAGATGPITSLHATTSSIDSIQNALFTMASASGAASTTTSASKAQ	This protein is part of the following components: cytoplasm, nucleus, and transcription regulator complex. This protein is involved in the following processs: radial glial cell differentiation, positive regulation of transcription by RNA polymerase II, Notch signaling pathway, regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, regulation of apoptotic process, and multicellular organism development. This protein is located in the following components: cytoplasm, and nucleus. This protein is involved in signal transduction: Notch signaling pathway. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: DNA binding, and sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: positive regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, and positive regulation of transcription, DNA-templated. This protein enables the following functions: DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA binding, and sequence-specific DNA binding.
MYPSGGVMLGLLAALQVAVQGTGAMPCQPGFTENEYNVMTADVITEGQVLLKVDFVDCGRGSGLRFESGDPADFRIDADGTVMAARTLQLTDRKGQSLEIKAKDENSQEQWMVHINFTQPKQVPVILFPRHSVLVKGDDSVNRVKRDWVIPPVNVLENSRKQFPEELVKIQSDKDKSNTLRYSVTGPGADQNPTGLFIIDPISGLLSVTKPLDREHIPNFHLRAHAVDINGNQMENPIDIIINVIDMNDNRPEFTHQIWNGTVDEGAKPGTFVMTVTSQDKDDPNTANGMLRYKILSQTPESPSSNMFTINNKTGKIITVAAGLDREKVPQYTLIIQATDMEGNPTYGLSNTATAVIRLLDVNDNAPEFTRETFHGEVPENRVNVIVTNLTVTDKDEPGTPAWNAVYRIISGDPTGRFSIPTDPVTNEGLVTVVKPVDFEMNRSFMLTVVADNEVPLASGIHRTRQSTATVSIRVIDVNESPNFDPNPKQIKLEEGLPQWSMLTTFTAHDPDRYMQQTISYSKLYDPANWLEIDPNNGRISTIAVLDRESPYVKNNLYNATFMASDNGVPRASGTGTLQIYLLDINDNAPRVFPQEAEVCERPEPNAINITAVDGDLNPNAGPYAFELPNRPSDIRRNWTLTRISGDHAQLSLKISYLESGIYELPISITDSGNLPMSNTTYLRIKVCQCDHHGDCVDMERIMAAGLGTGAIIAILICIIILLVLVLMFVMWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTLEPDMIKPVGIRRLDERPMHSEPNYPIRSAAPHPGDIGEFIHEGLKAADTDPTAPPYDSLLVFDYEGSGSTAGSLSSLHSSSSGGDQDYDYLNDWGPRFRKLADMYGGNDD	This protein is part of the following components: intercalated disc, cytoplasm, integral component of presynaptic active zone membrane, lamellipodium, integral component of postsynaptic specialization membrane, neuron projection, adherens junction, perinuclear region of cytoplasm, integral component of membrane, cell surface, catenin complex, presynaptic membrane, apical part of cell, integral component of plasma membrane, postsynaptic density, membrane, and plasma membrane. This protein is involved in the following processs: cell-cell adhesion via plasma-membrane adhesion molecules, dorsal convergence, synapse assembly, auditory receptor cell stereocilium organization, brain development, axial mesoderm structural organization, dorsal fin morphogenesis, cardioblast differentiation, post-anal tail morphogenesis, ventricular system development, mesoderm morphogenesis, glial cell differentiation, commissural neuron axon guidance, hindbrain structural organization, semicircular canal morphogenesis, cell-cell adhesion, neural crest cell migration, axonal fasciculation, blood vessel morphogenesis, peripheral nervous system development, multicellular organism development, ectoderm development, calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, homophilic cell adhesion via plasma membrane adhesion molecules, adherens junction organization, spinal cord patterning, regulation of axonogenesis, cell morphogenesis, embryonic eye morphogenesis, cell-cell junction assembly, motor neuron migration, nervous system development, neuronal stem cell population maintenance, embryonic retina morphogenesis in camera-type eye, motor neuron axon guidance, neural tube development, regulation of signal transduction, cell migration involved in somitogenic axis elongation, embryonic pectoral fin morphogenesis, somitogenesis, establishment of epithelial cell apical/basal polarity, negative regulation of neural precursor cell proliferation, cell-cell adhesion mediated by cadherin, sensory epithelium regeneration, pigment cell development, cilium assembly, cartilage condensation, cell migration in hindbrain, cell differentiation, retina development in camera-type eye, tissue regeneration, odontogenesis, hindbrain development, midbrain development, neuron migration, generation of neurons, regulation of eye photoreceptor cell development, cell adhesion, axon guidance, regulation of synaptic transmission, glutamatergic, and neuron cell-cell adhesion. This protein is active in the following components: integral component of postsynaptic specialization membrane, cytoplasm, integral component of presynaptic active zone membrane, lamellipodium, apical part of cell, neuron projection, intercalated disc, and postsynaptic density. This protein is located in the following components: plasma membrane, presynaptic membrane, intercalated disc, integral component of plasma membrane, membrane, integral component of membrane, and perinuclear region of cytoplasm. This protein enables metal ion binding: calcium ion binding, and metal ion binding. This protein is part of membrane: presynaptic membrane, plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of plasma membrane, and integral component of membrane. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: metal ion binding, cytoskeletal protein binding, cadherin binding, and calcium ion binding.
MKISCFLLLILSLYFFQINQAIGPDTKKCVQRKNACHYFECPWLYYSVGTCYKGKGKCCQKRY	This protein is part of the following components: extracellular region, extracellular space, and cellular_component. This protein is involved in the following processs: defense response, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, innate immune response in mucosa, and defense response to bacterium. This protein acts upstream of or within the following process: biological_process. This protein is active in the following component: extracellular space. This protein is located in the following component: extracellular region. This protein is part of extracellular region: extracellular region. This protein enables the following functions: CCR6 chemokine receptor binding, and molecular_function.
MIKAMALSSAGVVSHLHPPSFSSSSGLSVNRVLFRNRNASPCGLSLPILNPSRSVLVFARGKNRKGFVSSSSSSPKKNKKKSLDGADNGGGEEEEDPFEALFNLLEEDLKNDNSDDEEISEEELEALADELARALGVGDDVDDIDLFGSVTGDVDVDVDNDDDDNDDDDNDDDDDDSEEDERPTKLKNWQLKRLAYALKAGRRKTSIKNLAAEVCLDRAYVLELLRDPPPKLLMLSATLPDEKPPVAAPENSSPDPSPVESLSAEDVVVEPKEKVKDEAVHVMQQRWSAQKRVKKAHIETLEKVYRRSKRPTNAVVSSIVQVTNLPRKRVLKWFEDKRAEDGVPDKRAPYQAPV	This protein is part of the following component: nucleus. This protein is involved in the following processs: induced systemic resistance, regulation of defense response by callose deposition, stomatal movement, abscisic acid-activated signaling pathway, jasmonic acid mediated signaling pathway, regulation of transcription by RNA polymerase II, regulation of jasmonic acid mediated signaling pathway, defense response, defense response to oomycetes, defense response to bacterium, regulation of abscisic acid-activated signaling pathway, response to abscisic acid, response to fungus, regulation of defense response, cellular oxidant detoxification, defense response to fungus, and response to water deprivation. This protein is active in the following component: nucleus. This protein is located in the following component: nucleus. This protein is involved in signal transduction: jasmonic acid mediated signaling pathway, and abscisic acid-activated signaling pathway. This protein enables catalytic activity: peroxidase activity, and oxidoreductase activity. This protein enables DNA binding: DNA binding. This protein is part of nucleus: nucleus. This protein enables the following functions: DNA-binding transcription factor activity, DNA binding, peroxidase activity, oxidoreductase activity, protein binding, and DNA-binding transcription factor activity, RNA polymerase II-specific.
MTAPWRRLRSLVWEYWAGLLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQLPIDSDDSRPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTEYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSESGLLDGVMMTDAALLYDAVHIVSVCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRALTADYALLMESTTIEYVTQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCPEEENKEASALGIQKIGGIFIVLAAGLVLSVLVAVGEFVYKLRKTAEREQRSFCSTVADEIRFSLTCQRRVKHKPQPPMMVKTDAVINMHTFNDRRLPGKDSMACSTSLAPVFP	This protein is part of the following components: integral component of plasma membrane, dendrite, dendrite cytoplasm, synapse, postsynaptic membrane, perikaryon, axon, presynaptic membrane, membrane, glutamatergic synapse, terminal bouton, cell junction, plasma membrane, integral component of membrane, and kainate selective glutamate receptor complex. This protein is involved in the following processs: regulation of postsynaptic membrane potential, regulation of membrane potential, adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway, glutamate receptor signaling pathway, ion transmembrane transport, ion transport, negative regulation of synaptic transmission, glutamatergic, regulation of presynaptic membrane potential, ionotropic glutamate receptor signaling pathway, G protein-coupled glutamate receptor signaling pathway, modulation of chemical synaptic transmission, and synaptic transmission, glutamatergic. This protein is active in the following components: postsynaptic membrane, plasma membrane, and presynaptic membrane. This protein is located in the following components: synapse, dendrite cytoplasm, integral component of plasma membrane, axon, dendrite, postsynaptic membrane, cell junction, integral component of membrane, perikaryon, membrane, glutamatergic synapse, terminal bouton, and plasma membrane. This protein is involved in signal transduction: ionotropic glutamate receptor signaling pathway, glutamate receptor signaling pathway, G protein-coupled glutamate receptor signaling pathway, and adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway. This protein is part of membrane: postsynaptic density membrane, plasma membrane, presynaptic membrane, membrane, and postsynaptic membrane. This protein is part of integral component of membrane: integral component of plasma membrane, and integral component of membrane. This protein is part of cytoplasm: dendrite cytoplasm. This protein is involved in cation transport: ion transport, and ion transmembrane transport. This protein enables the following functions: glutamate receptor activity, adenylate cyclase inhibiting G protein-coupled glutamate receptor activity, ligand-gated ion channel activity, signaling receptor activity, ion channel activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity, ligand-gated ion channel activity involved in regulation of presynaptic membrane potential, and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential.
MRPIILQGHERPLTQIKYNHDGDLLFSCAKDKVINVWFSHNGERLGTYEGHTGAIWTCDINKSSTLMVSGAADNTMRLWDVKTGKQLYKWEFPTAVKRVEFNEDDTRILAVTEERMGYAGTVTVFRVPISESDAAAETPLYVITTRESKATVAGWSYLSKFLFTGHEDGSVSRYDAITGEFVESKQVHNSGSTITDLQFYPDRTYFITSCKDTTAKAIDVDSFEVIKTYLTDTPLNTSSFTPVQDFVILGGGQEARDVTTTAARQGKFEARFYHAILEEELGRVKGHFGPINTIAVHPKGTGYASGGEDGYVRVHFFDKNYFDFKYTL	This protein is part of the following components: cytosol, eukaryotic translation initiation factor 3 complex, nuclear periphery, eukaryotic translation initiation factor 3 complex, eIF3e, cytoplasm, eukaryotic 48S preinitiation complex, cytoplasmic stress granule, eukaryotic 43S preinitiation complex, eukaryotic translation initiation factor 3 complex, eIF3m, and nucleus. This protein is involved in the following processs: formation of cytoplasmic translation initiation complex, translation, translational initiation, and cytoplasmic translational initiation. This protein contributes to the following function: translation initiation factor activity. This protein is located in the following components: cytosol, nucleus, nuclear periphery, cytoplasmic stress granule, and cytoplasm. This protein is involved in metabolic process: translational initiation, and cytoplasmic translational initiation. This protein enables RNA binding: RNA binding, and translation initiation factor activity. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in translation: translation. This protein enables the following functions: RNA binding, translation initiation factor activity, and protein binding.
MDLWRVFLTLALAVSSDMFPGSGATPATLGKASPVLQRINPSLRESSSGKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECPDYVSAGANSCYFNSSYTSIWIPYCIKLTTNGDLLDEKCFTVDEIVQPDPPIGLNWTLLNISLPGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLYSLRLDKEHEVRVRSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGIFGVAVMLFVVIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFIELDIDDADEKTEESDTDRLLSDDQEKSAGILGAKDDDSGRTSCYDPDILDTDFHTSDMCDGTSEFAQPQKLKAEADLLCLDQKNLKNSPYDASLGSLHPSITLTMEDKPQPLLGSETESTHQLPSTPMSSPVSLANIDFYAQVSDITPAGGVVLSPGQKIKAGLAQGNTQLEVAAPCQENYSMNSAYFCESDAKKCIAAAPHMEATTCVKPSFNQEDIYITTESLTTTARMSETADTAPDAEPVPDYTTVHTVKSPRGLILNATALPLPDKKKFLSSCGYVSTDQLNKIMQ	This protein is part of the following components: extrinsic component of membrane, external side of plasma membrane, cytoplasmic ribonucleoprotein granule, extracellular space, cytosol, extracellular region, nucleus, plasma membrane, membrane, receptor complex, integral component of membrane, cytoplasm, cell surface, mitochondrion, integral component of plasma membrane, neuronal cell body, and growth hormone receptor complex. This protein is involved in the following processs: insulin-like growth factor receptor signaling pathway, growth hormone receptor signaling pathway, response to morphine, endocytosis, response to food, positive regulation of receptor signaling pathway via JAK-STAT, hormone metabolic process, taurine metabolic process, negative regulation of neuron death, positive regulation of cell differentiation, positive regulation of multicellular organism growth, cartilage development involved in endochondral bone morphogenesis, positive regulation of peptidyl-tyrosine phosphorylation, response to cycloheximide, receptor internalization, response to interleukin-1, cellular response to insulin stimulus, regulation of multicellular organism growth, activation of Janus kinase activity, response to growth hormone, response to estradiol, cytokine-mediated signaling pathway, response to glucocorticoid, response to peptide hormone, hormone-mediated signaling pathway, response to hormone, cellular response to hormone stimulus, receptor signaling pathway via JAK-STAT, and response to cytokine. This protein is not involved in the following processs: receptor internalization, and response to cycloheximide. This protein is active in the following components: cytosol, and external side of plasma membrane. This protein is located in the following components: cytoplasm, integral component of plasma membrane, cytosol, integral component of membrane, cytoplasmic ribonucleoprotein granule, cell surface, plasma membrane, mitochondrion, extracellular space, extrinsic component of membrane, neuronal cell body, nucleus, membrane, and extracellular region. This protein is involved in signal transduction: insulin-like growth factor receptor signaling pathway, receptor signaling pathway via JAK-STAT, hormone-mediated signaling pathway, growth hormone receptor signaling pathway, and cytokine-mediated signaling pathway. This protein is involved in metabolic process: receptor internalization, hormone metabolic process, and taurine metabolic process. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of membrane, and integral component of plasma membrane. This protein is part of mitochondrion: mitochondrion. This protein is part of extracellular region: extracellular region. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in phosphorylation: activation of Janus kinase activity. This protein enables the following functions: SH2 domain binding, protein kinase binding, growth hormone receptor activity, protein phosphatase binding, peptide hormone binding, cytokine binding, protein homodimerization activity, cytokine receptor activity, identical protein binding, and growth factor binding.
MDPKEKNYDASAITVLEGLQAVRERPGMYIGDTGITGLHHLVYEVVDNSIDEAMAGYCSRIDVRILEDGGIVIVDNGRGIPIEVHERESAKQGREVSALEVVLTVLHAGGKFDKDSYKVSGGLHGVGVSCVNALSEKLVATVFKDKKCYQMEFSRGIPVTPLQYVSVSDRQGTEIVFYPDPKIFSTCTFDRSILMKRLRELAFLNRGITIVFEDDRDVSFDKVTFFYEGGIQSFVSYLNQNKESLFSEPIYICGTRVGDDGEIEFEAALQWNSGYSELVYSYANNIPTRQGGTHLTGFSTALTRVINTYIKAHNLAKNNKLALTGEDIREGLTAVISVKVPNPQFEGQTKQKLGNSDVSSVAQQVVGEALTIFFEENPQIARMIVDKVFVAAQAREAAKKARELTLRKSALDSARLPGKLIDCLEKDPEKCEMYIVEGDSAGGSAKQGRDRRFQAILPIRGKILNVEKARLQKIFQNQEIGTIIAALGCGIGADNFNLSKLRYRRIIIMTDADVDGSHIRTLLLTFFYRHMTALIENECVYIAQPPLYKVSKKKDFRYILSEKEMDSYLLMLGTNESSILFKSTERELRGEALESFINVILDVESFINTLEKKAIPFSEFLEMYKEGIGYPLYYLAPATGMQGGRYLYSDEEKEEALAQEETHKFKIIELYKVAVFVDIQNQLKEYGLDISSYLIPQKNEIVIGNEDSPSCNYSCYTLEEVINYLKNLGRKGIEIQRYKGLGEMNADQLWDTTMNPEQRTLIHVSLKDAVEADHIFTMLMGEEVPPRREFIESHALSIRINNLDI	This protein is part of the following components: chromosome, and cytoplasm. This protein is involved in the following processs: DNA-dependent DNA replication, and DNA topological change. This protein is located in the following components: chromosome, and cytoplasm. This protein is involved in metabolic process: DNA-dependent DNA replication, and DNA topological change. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: DNA topoisomerase activity, DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity, and isomerase activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: DNA binding. This protein enables the following functions: DNA topoisomerase activity, isomerase activity, nucleotide binding, DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity, ATP binding, DNA binding, and metal ion binding.
MPAFFEGEFWQIANPELWVGVGLILFIAIVIWAKAPAMIAGKLDETAAKIQTDLDEAARIRAEAEALLATIRAEREETERQAIAMLAAAKADVAQMEIEAKAKLEDQIKRRAEMAERKIAQSEAQAQADVKAAAVDLAAQIAEQVLMARLAAGGSDGLVDTAIGQIGAKLQ	This protein is part of the following components: plasma membrane, membrane, proton-transporting ATP synthase complex, coupling factor F(o), and integral component of membrane. This protein is involved in the following processs: ion transport, ATP synthesis coupled proton transport, and ATP biosynthetic process. This protein is located in the following components: membrane, plasma membrane, and integral component of membrane. This protein is involved in metabolic process: ATP biosynthetic process. This protein enables catalytic activity: proton-transporting ATP synthase activity, rotational mechanism. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in cation transport: ion transport, and ATP synthesis coupled proton transport. This protein enables the following functions: proton transmembrane transporter activity, and proton-transporting ATP synthase activity, rotational mechanism.
MSKLRVMSLFSGIGAFEAALRNIGVDYELIGFSEIDKYAIKSYCAIHNVSETLNVGDISKAKKDNIPYFDLLTSGFPCPTFSVAGGRDGMEYKCSNCSHEHLITYEDYKKGVKCPKCEAVSKAKDERGTLFFETALLAEEKKPKFVILENVKGLINSGNGQVLRIISETMNNIGYRIDLELLNSKFFNVPQNRERVYIIGIREDLVENEQWVVGQKRNDVLSKGKKRLQEINIKSFNFKWPLQDTVTKRLREILEDFVDEKYYLNEEKTKKLVEQLGTAPLQKQEVREPLMVGHVDLKGHDAIKRVYSPEGLSPTLTTMGGGHREPKIAEKQKEVRAVLTPEREEKRQNGRRFKENGEPAFTVNTIDRHGVAIGEYPKYKIRKLSPLECWRLQAFDDEDFEKAFAAGISNSQLYKQAGNSITVSVLESIFQELIHTYVNKESE	This protein is involved in the following processs: methylation, DNA restriction-modification system, and C-5 methylation of cytosine. This protein is involved in metabolic process: DNA restriction-modification system. This protein enables transferase activity: transferase activity, DNA (cytosine-5-)-methyltransferase activity, and methyltransferase activity. This protein is involved in methylation: C-5 methylation of cytosine, and methylation. This protein enables the following functions: methyltransferase activity, transferase activity, and DNA (cytosine-5-)-methyltransferase activity.
MHSSSSFIITSLEEEEKKPPAHHLHQQSIEDVGSVTSSATLLLLDSATWMMPSSTTQPHISEISGNECAACAQPILDRYVFTVLGKCWHQSCLRCCDCRAPMSMTCFSRDGLILCKTDFSRRYSQRCAGCDGKLEKEDLVRRARDKVFHIRCFQCSVCQRLLDTGDQLYIMEGNRFVCQSDFQTATKTSTPTSIHRPVSNGSECNSDVEEDNVDACDEVGLDDGEGDCGKDNSDDSNSAKRRGPRTTIKAKQLETLKNAFAATPKPTRHIREQLAAETGLNMRVIQVWFQNRRSKERRMKQLRFGGYRQSRRPRRDDIVDMFPNDQQFYPPPPPSNVQFFCDPYTTSPNNPETIQMAPQFAVPTENMNMVPEPYTEQSATPPEFNEDTFACIYSTDLGKPTPVSW	This protein is part of the following component: nucleus. This protein is involved in the following processs: regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, neuron differentiation, regulation of cell differentiation, multicellular organism development, positive regulation of vulval development, axonal fasciculation, oviposition, regulation of cell migration, and cell fate specification. This protein is active in the following component: nucleus. This protein is located in the following component: nucleus. This protein enables metal ion binding: metal ion binding. This protein enables DNA binding: RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA binding, and sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: positive regulation of transcription by RNA polymerase II, and regulation of transcription, DNA-templated. This protein enables the following functions: RNA polymerase II transcription regulatory region sequence-specific DNA binding, metal ion binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription factor activity, and DNA binding.
MPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAAQGPAAPRDLATFASTSTLHGLGRACGPGPHGLRRTLWVLALLTSLAAFLYQAASLARGYLTRPHLVAMDPAAPAPVAGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQLADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPQSSLPSRAGGMGSGLEIMLDIQQEEYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQKQRLTYLPQPWGNCRAESKLREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGNETICPPNIYIECADHTLDSLGGGSEGPCFCPTPCNLTRYGKEISMVKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLRTSTGGISTLGLQELKEQSPCPNRGRAEGGGASNLLPNHHHPHGPPGSLFEDFAC	This protein is part of the following components: integral component of membrane, membrane, and integral component of plasma membrane. This protein is involved in the following processs: ion transport, behavioral fear response, sodium ion transmembrane transport, and sodium ion transport. This protein is active in the following component: integral component of plasma membrane. This protein is located in the following components: integral component of membrane, and membrane. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in cation transport: sodium ion transport, ion transport, and sodium ion transmembrane transport. This protein enables the following functions: ligand-gated sodium channel activity, and sodium channel activity.
MLEDALVPDDKLIYVSPENLYYCYANDTIDQDDKWTSIQPQQGYIPILSANLRAYKIELLKKLRFSGQNNVSPSIKKEKKNLEPNKKITTKPTESTGSKKYLIPEQFIPDSLEKQLRTLTVILKDALYLGKNNRFIKENEVVSDDTRLLILDEFLKLIIPNYIDSLANWTLVDLNKGTDDESLLYLRFNESGTQSMISFYKKHSKMAKYMEIHYDTNTEKYINDNFKDDGDEDNVEAEQSHSVGEILKSMETAFEKARSQVGTFKGDINDDQDDKINYKIDYNTLLDIPSDSLEQLTKEILNFRTKVIDIEKQKQLRQQYEDNERRQKHMTQLFEKLRKGTKSNDSNRNMDIESTDTINDSDSEEDDDEEDEDDLAIEKRKEEKRKEEEARKYRALLKDYETTIEPHLHLLSQQYKQNLEYEKELAANREANVKDLLRQANDIYYDKDRSFKDREEQEDKLDREKYGDIIIEDIVIDDDRKGQKKLLEKDKKVKKAGEPAIKINLAFKKAMDNSIQDKRDKAEDIEPVSQPIEARSTNRYAALKEKRVVDELVKELLGVYEDDVVAYVFEILEKPEMSDEKKQSELVTEMEDLFDKEGAVQFAEQVFKALDEA	This protein is part of the following components: nucleus, cytoplasm, and spliceosomal complex. This protein is involved in the following processs: RNA splicing, and mRNA processing. This protein is located in the following components: cytoplasm, and nucleus. This protein is involved in metabolic process: mRNA processing, and RNA splicing. This protein enables RNA binding: RNA binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables the following function: RNA binding.
MNWLPEAEAEEHLKGILSGDFFDGLTNHLDCPLEDIDSTNGEGDWVARFQDLEPPPLDMFPALPSDLTSCPKGAARVRIPNNMIPALKQSCSSEALSGINSTPHQSSAPPDIKVSYLFQSLTPVSVLENSYGSLSTQNSGSQRLAFPVKGMRSKRRRPTTVRLSYLFPFEPRKSTPGESVTEGYYSSEQHAKKKRKIHLITHTESSTLESSKSDGIVRICTHCETITTPQWRQGPSGPKTLCNACGVRFKSGRLVPEYRPASSPTFIPSVHSNSHRKIIEMRKKDDEFDTSMIRSDIQKVKQGRKKMV	This protein is part of the following component: nucleus. This protein is involved in the following processs: cell differentiation, and regulation of transcription, DNA-templated. This protein is active in the following component: nucleus. This protein is located in the following component: nucleus. This protein enables metal ion binding: zinc ion binding, and metal ion binding. This protein enables DNA binding: DNA binding, and sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: regulation of transcription, DNA-templated. This protein enables the following functions: zinc ion binding, protein binding, DNA binding, sequence-specific DNA binding, DNA-binding transcription factor activity, and metal ion binding.
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNERAKASAESCSC	This protein is part of the following components: phagocytic vesicle, cytoplasmic vesicle, phagocytic vesicle membrane, endosome, cytoplasm, lipid droplet, endosome membrane, melanosome membrane, cytosol, endomembrane system, autophagosome membrane, terminal bouton, extrinsic component of lysosome membrane, lysosomal membrane, alveolar lamellar body, late endosome membrane, Golgi apparatus, phagophore assembly site membrane, anchored component of synaptic vesicle membrane, late endosome, lysosome, and membrane. This protein is involved in the following processs: phagosome acidification, endosome to lysosome transport, phagosome-lysosome fusion, positive regulation of protein catabolic process, protein targeting to lysosome, epidermal growth factor catabolic process, establishment of vesicle localization, lipophagy, bone resorption, lipid metabolic process, early endosome to late endosome transport, positive regulation of viral process, protein to membrane docking, retrograde transport, endosome to Golgi, viral release from host cell, protein transport, autophagosome assembly, negative regulation of exosomal secretion, positive regulation of exosomal secretion, autophagy, lipid catabolic process, and endosome to plasma membrane protein transport. This protein colocalizes with the following components: lysosome, late endosome, and retromer complex. This protein is active in the following components: late endosome, lysosome, and phagocytic vesicle. This protein is located in the following components: cytoplasm, phagocytic vesicle, phagocytic vesicle membrane, alveolar lamellar body, extrinsic component of lysosome membrane, lipid droplet, melanosome membrane, cytoplasmic vesicle, phagophore assembly site membrane, anchored component of synaptic vesicle membrane, membrane, cytosol, lysosome, lysosomal membrane, late endosome, Golgi apparatus, terminal bouton, endosome, late endosome membrane, endosome membrane, and autophagosome membrane. This protein enables hydrolase activity: GTPase activity. This protein is involved in signal transduction: Rab protein signal transduction. This protein is involved in metabolic process: lipophagy, epidermal growth factor catabolic process, and autophagy. This protein enables nucleotide binding: nucleotide binding, GDP binding, and GTP binding. This protein is part of membrane: membrane, melanosome membrane, phagocytic vesicle membrane, autophagosome membrane, endosome membrane, lysosomal membrane, late endosome membrane, and phagophore assembly site membrane. This protein is part of cytoplasm: cytoplasm. This protein is involved in lipid metabolic process: lipid metabolic process, and lipid catabolic process. This protein is part of cytosol: cytosol. This protein is involved in protein transport: protein transport, intracellular protein transport, and protein targeting to lysosome. This protein enables the following functions: GTP binding, GTPase activity, G protein activity, retromer complex binding, GDP binding, nucleotide binding, protein binding, small GTPase binding, small GTPase binding, and hydrolase activity.
MRYWYLRLAVFLGALAMPAWWLYQAWIFALGPDPGKTLVDRLGLGALVLLLLTLAMTPLQKLSGWPGWIAVRRQLGLWCFTYALLHLSAYCVFILGLDWGQLGIELSKRPYIIVGMLGFICLFLLAITSNRFAMRKLGSRWKKLHRLVYLILGLGLLHMLWVVRADLEEWTLYAVVGASLMLLRLPSIARRLPRLRGRPGVS	This protein is part of the following components: membrane, plasma membrane, integral component of membrane, and integral component of plasma membrane. This protein is involved in the following processs: protein repair, and electron transport chain. This protein is located in the following components: integral component of plasma membrane, integral component of membrane, plasma membrane, and membrane. This protein is involved in metabolic process: electron transport chain, and protein repair. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: electron transfer activity. This protein enables nucleotide binding: FMN binding. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of plasma membrane, and integral component of membrane. This protein enables the following functions: FMN binding, heme binding, metal ion binding, and electron transfer activity.
MEPIVKQENPVTTSTLSTWKPAARNKTIPPPESVIELSSSNEGSELGENLDEIAEIQSVDRTGGDDVSGTKRARSDSIASPAKRLAVMIPDDDEEFLLSTTSGQAILALPATPCNVVAAPSSWGSCKQFWKAGDYEGTSGGDWEVSAGGFDHVRVHPKFLHSNATSHKWSLGAFAELLDNALDEVRSGATFVNVDMIQNRKDGSKMILIEDNGGGMNPEKMRHCMSLGYSAKSKLADTIGQYGNGFKTSTMRLGADVIVFSRCLGKDGKSSTQSIGLLSYTFLKSTGKEDIVVPMLDYERRDSEWCPITRSSVSDWEKNVETVVQWSPYATEEELLCQFNLMKKHGTRIIIYNLWEDDEGMLELDFDTDPHDIQLRGVNRDDKNIVMASQFPNSRHYLTYKHSLRSYASILYLKISHEFRIILRGKDVEHHNIVNDMMQTEKITYRPKEAADVSQLSAVVTIGFVKDAKHHVDVQGFNVYHKNRLIKPFWRIWNAAGSDGRGVIGVLEANFVEPAHDKQGFERTTVLSRLEARLLHMQKDYWRSKCHKIGYAKRQGRKSAKDTEKDTEDRESSPEFDPKGSASSRKRTVPSSFKTPTAAPRFNTPTAASEKFNPRSNVNGGGKGSVKVSKDIGYKSSEKGGKLGNSFSKSNKRAKPQGARAVEVTNSDDDYDCDSSPERNVTELPGKSSELPKPQSGPRTLSQLEQENNELRERLDKKEEVFLLLQKDLRRERELRKTLEAEVETLKNKLKEMDKEQASLIDVFAEDRDRRDKEEENLRIKLEEASNTIQKLIDGKARGR	This protein is part of the following components: nuclear body, nucleoplasm, and nucleus. This protein is involved in the following processs: regulation of DNA methylation, positive regulation of defense response to oomycetes, gene silencing by RNA, nucleic acid phosphodiester bond hydrolysis, chromatin organization, regulation of chromatin silencing, regulation of DNA repair, cellular response to DNA damage stimulus, phosphorylation, defense response, and DNA repair. This protein is located in the following components: nucleoplasm, nucleus, and nuclear body. This protein enables hydrolase activity: ATP hydrolysis activity, endonuclease activity, nuclease activity, and hydrolase activity. This protein is involved in metabolic process: nucleic acid phosphodiester bond hydrolysis. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein is involved in cellular response to DNA damage stimulus: DNA repair, and cellular response to DNA damage stimulus. This protein enables RNA binding: RNA binding. This protein enables DNA binding: DNA binding. This protein is part of nucleus: nucleus. This protein enables transferase activity: kinase activity, and transferase activity. This protein is involved in phosphorylation: phosphorylation. This protein enables the following functions: ATP hydrolysis activity, RNA binding, ATP binding, kinase activity, nuclease activity, protein self-association, nucleotide binding, transferase activity, hydrolase activity, endonuclease activity, and DNA binding.
APKNIVLFGATGMTGQVTLGQALE	This protein is part of the following component: cytoplasm. This protein is located in the following component: cytoplasm. This protein enables catalytic activity: riboflavin reductase (NADPH) activity, and oxidoreductase activity. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: oxidoreductase activity, and riboflavin reductase (NADPH) activity.
MAEAVFRAPKRKRRVYESYESPLPIPFGQDQGPRKEFRIFQAEMISNNVVVRGTEDMEQLYGKGYFGKGILSRSRPNFTIANPTLAARWKGVQTDMPIITSEKYQHRVEWARDFLRRQGHDESTVQKILTDYTEPLELPCREEKEETPQHEPLSSKADSSLEGRVEKDELPVTPGGAGQSDDLPGLGTHSDCLQEGPGHATLAAASPSSHNGHVAEDPEVLPQETLVPQGGLWPEASSQAAGEKRAAHEYVLIEEELCGAQEEEAAAASDEKLLKRKKLVCRRNPYRIFEYLQLSLEEAFFLAYALGCLSIYYEKEPLTIVKLWQAFTAVQPTFRTTYMAYHYFRSKGWVPKVGLKYGTDLLLYRKGPPFYHASYSVIIELLDDNYEGSLRRPFSWKSLAALSRVSGNVSKELMLCYLIKPSTMTAEDMETPECMKRIQVQEVILSRWVSSRERSDQDEL	This protein is part of the following components: centrosome, nucleoplasm, nucleolus, nucleus, tRNA-intron endonuclease complex, and cytosol. This protein is involved in the following processs: nucleic acid phosphodiester bond hydrolysis, tRNA processing, tRNA splicing, via endonucleolytic cleavage and ligation, tRNA-type intron splice site recognition and cleavage, RNA phosphodiester bond hydrolysis, endonucleolytic, RNA phosphodiester bond hydrolysis, and mRNA processing. This protein acts upstream of or within the following process: tRNA splicing, via endonucleolytic cleavage and ligation. This protein is located in the following components: nucleolus, centrosome, nucleoplasm, cytosol, and nucleus. This protein enables hydrolase activity: tRNA-intron endonuclease activity, and nuclease activity. This protein is involved in metabolic process: tRNA-type intron splice site recognition and cleavage, nucleic acid phosphodiester bond hydrolysis, RNA phosphodiester bond hydrolysis, endonucleolytic, RNA phosphodiester bond hydrolysis, and mRNA processing. This protein enables catalytic activity: lyase activity. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is not involved in tRNA processing: tRNA splicing, via endonucleolytic cleavage and ligation, and tRNA processing. This protein enables the following functions: lyase activity, nucleic acid binding, nuclease activity, and tRNA-intron endonuclease activity.
MWSSWAWTWSWSGAAAVAVAAAAAWVAVYAAAARAAEALWWRPRRVERHFAAQGVRGPGYRFFVGSSIELVRLMVDAASRPMEPPTSHDILPRVLPFYHHWRKLYGPMHLIWFGRTPRLVVSEPELIREVLLTRADHFDRYEAHPMICQFEGYGLSNLHGERWARRRRVLTPAFHTENLRMIAPFVAGTVTRMLDELAERARAGGAGEAEVDVAEWFQRVPQEAITFAAFGRRNYDDGAAVFRLQDELAGYATEAHSKVYIPGYRFLPTRKNRRVWQLDREIRSHLAKFVTGLQSCSSSHGDDADDGGDGGGGMREFMSFMAPAMTAGEIIEESKNFFFAGKETLSNLLTWTTVALAMHPEWQERARREVVAVCGRGDLPTKDHLPKLKTLGMILNETLRLYPPAVAMIRTAKEDVELGGCVVPAGTEVMIPIMAVHHDAAAWGDDAAEFNPARFAADDDGGRRRHPMAFMPFGGGARVCIGQNMALMEAKVALAVVLRRFEFRLSPAYVHAPRVLMILSPQFGAPVIFRPLTSAAA	This protein is part of the following components: integral component of membrane, and membrane. This protein is involved in the following processs: brassinosteroid homeostasis, and brassinosteroid metabolic process. This protein is located in the following components: membrane, and integral component of membrane. This protein enables metal ion binding: metal ion binding, and iron ion binding. This protein enables catalytic activity: monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, and oxidoreductase activity. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in lipid metabolic process: brassinosteroid metabolic process. This protein enables the following functions: monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, heme binding, metal ion binding, oxidoreductase activity, and iron ion binding.
MLAIRSSNYLRCIPSLCTKTQISQFSSVLISFSRQISHLRLSSCHRAMSSSRPSAFDALMSNARAAAKKKTPQTTNLSRSPNKRKIGETQDANLGKTIVSEGTLPKTEDLLEPVSDSANPRSDTSSIAEDSKTGAKKAKTLSKTDEMKSKIGLLKKKPNDFDPEKMSCWEKGERVPFLFVALAFDLISNESGRIVITDILCNMLRTVIATTPEDLVATVYLSANEIAPAHEGVELGIGESTIIKAISEAFGRTEDHVKKQNTELGDLGLVAKGSRSTQTMMFKPEPLTVVKVFDTFRQIAKESGKDSNEKKKNRMKALLVATTDCEPLYLTRLLQAKLRLGFSGQTVLAALGQAAVYNEEHSKPPPNTKSPLEEAAKIVKQVFTVLPVYDIIVPALLSGGVWNLPKTCNFTLGVPIGPMLAKPTKGVAEILNKFQDIVFTCEYKYDGERAQIHFMEDGTFEIYSRNAERNTGKYPDVALALSRLKKPSVKSFILDCEVVAFDREKKKILPFQILSTRARKNVNVNDIKVGVCIFAFDMLYLNGQQLIQENLKIRREKLYESFEEDPGYFQFATAVTSNDIDEIQKFLDASVDVGCEGLIIKTLDSDATYEPAKRSNNWLKLKKDYMDSIGDSVDLVPIAAFHGRGKRTGVYGAFLLACYDVDKEEFQSICKIGTGFSDAMLDERSSSLRSQVIATPKQYYRVGDSLNPDVWFEPTEVWEVKAADLTISPVHRAATGIVDPDKGISLRFPRLLRVREDKKPEEATSSEQIADLYQAQKHNHPSNEVKGDDD	This protein is part of the following components: nucleus, nucleolus, mitochondrion, and cytoplasm. This protein is involved in the following processs: double-strand break repair, DNA recombination, DNA ligation, lagging strand elongation, DNA biosynthetic process, single strand break repair, DNA ligation involved in DNA repair, DNA repair, cellular response to DNA damage stimulus, DNA demethylation, cell cycle, DNA replication, and cell division. This protein is active in the following components: mitochondrion, cytoplasm, and nucleus. This protein is located in the following components: nucleolus, mitochondrion, and nucleus. This protein is involved in metabolic process: DNA biosynthetic process, DNA ligation involved in DNA repair, DNA ligation, lagging strand elongation, DNA demethylation, DNA replication, and DNA recombination. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: ligase activity, DNA ligase activity, and DNA ligase (ATP) activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is involved in cellular response to DNA damage stimulus: DNA repair, cellular response to DNA damage stimulus, double-strand break repair, and single strand break repair. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: DNA binding. This protein is part of nucleus: nucleus. This protein is involved in cell cycle: cell cycle. This protein is involved in cell division: cell division. This protein enables the following functions: metal ion binding, DNA ligase (ATP) activity, ATP binding, nucleotide binding, DNA binding, DNA ligase activity, and ligase activity.
MNIEATLKNYDLSKLNVVTIASHSSLQILRGAKRHGLGTVAVAKPGSGWFYRRFNFIDNVIEIDLGSMEQLAGDLVKNNAILIPHGSYVEYVGWRRALSMPIPTFGNRYIIEWEADQRKKMRLLEYAGIPIPRSFNDPTQVDRPVIVKLSGAKGGRGYFIAKDAGELAGKLSSINTDDYIIQEYVIGVPAYYHYFDSKVYDRVELFGMDLRYESNVDGRLFNLAEPTFVVTGNIPLVLRESLLPTVQKYGEDFSRAVAELVPPGMIGPYSLESIIKDDLSIVVFEFSGRIVAGTNVYMGVGSPYSVLYFNEPMDMGERIAHEIVNAVKRGKLINVLT	This protein is involved in the following processs: 'de novo' IMP biosynthetic process, purine nucleotide biosynthetic process, and IMP biosynthetic process. This protein is involved in metabolic process: purine nucleotide biosynthetic process, IMP biosynthetic process, and 'de novo' IMP biosynthetic process. This protein enables metal ion binding: magnesium ion binding, and metal ion binding. This protein enables catalytic activity: ligase activity, and ligase activity, forming carbon-nitrogen bonds. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein enables the following functions: nucleotide binding, ligase activity, ATP binding, metal ion binding, ligase activity, forming carbon-nitrogen bonds, and magnesium ion binding.
MSGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEVVQTGAKNIEITVVKPDSDIVALSSEEINQYVTQIEQEKQEQQEQDKKKKSNH	This protein is part of the following components: nuclear outer membrane-endoplasmic reticulum membrane network, proteasome complex, proteasome core complex, alpha-subunit complex, proteasome storage granule, cytoplasm, mitochondrion, proteasome core complex, and nucleus. This protein is involved in the following processs: proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, proteasomal protein catabolic process, ubiquitin-dependent protein catabolic process, proteolysis involved in cellular protein catabolic process, and proteolysis. This protein is active in the following components: nucleus, and cytoplasm. This protein is located in the following components: nuclear outer membrane-endoplasmic reticulum membrane network, proteasome storage granule, mitochondrion, cytoplasm, and nucleus. This protein enables hydrolase activity: threonine-type endopeptidase activity, peptidase activity, endopeptidase activity, and hydrolase activity. This protein is part of membrane: nuclear outer membrane-endoplasmic reticulum membrane network. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is involved in proteolysis: proteasomal protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis, ubiquitin-dependent protein catabolic process, proteasomal ubiquitin-independent protein catabolic process, and proteolysis involved in cellular protein catabolic process. This protein enables the following functions: molecular_function, threonine-type endopeptidase activity, protein binding, hydrolase activity, peptidase activity, and endopeptidase activity.
MRGKKRIGLLFLLIAVVVGGGGLLLAQKVLHKTSDTAFCLSCHSMSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDSDDKFEAHRQEMAETVWKELKATDSATCRSCHSFDAMDIASQSESAQKMHNKAQKDSETCIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKTSHIGELATVNPGTDLTVVDASGKQPIVLLQGYQMQGSENTLYLAAGQRLALATLSEEGIKALTVNGEWQADEYGNQWRQASLQGALTDPALADRKPLWQYAEKLDDTYCAGCHAPIAADHYTVNAWPSIAKGMGARTSMSENELDILTRYFQYNAKDITEKQ	This protein is part of the following components: integral component of plasma membrane, integral component of membrane, Gram-negative-bacterium-type cell wall, plasma membrane, and membrane. This protein is involved in the following processs: anaerobic respiration, and anaerobic electron transport chain. This protein is located in the following components: integral component of membrane, integral component of plasma membrane, membrane, plasma membrane, and Gram-negative-bacterium-type cell wall. This protein is involved in metabolic process: anaerobic electron transport chain, and anaerobic respiration. This protein enables metal ion binding: iron ion binding, and metal ion binding. This protein enables catalytic activity: electron transfer activity. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of plasma membrane, and integral component of membrane. This protein enables the following functions: electron transfer activity, heme binding, metal ion binding, and iron ion binding.
MSSSLASDTPRLPSIDTLLRHQACLPLIDRHGREGVLATLRQLLDDLRNLVRNGELTPAELAPEILLGRTGERLAAQQRSQVRRVFNLTGTVLHTNLGRALLPEAAIEAMQTAARYPLNLEFDLATGKRGDRDDLIEGLIRELTGAEAVTVVNNNAAAVLLALNSLGARKEGIISRGELIEIGGAFRIPDIMARAGVKLHEIGTTNRTHARDYEAAIGPRTGLLMRVHCSNYSIQGFTTQVPTAELASIAHQRDLPLLEDLGSGSLLDLTRWGLPAEPTVRQALADGADIVTFSGDKLLGGPQAGIIVGRKDLIARIKKNPLKRALRVDKITLAALEAVLALYRNPDRLAERLPTLRLLTRSQAEIQAQAERLAPEVKAHLGEQWAVSVAPALGMIGSGSQPVARLPSAALCLRPQVSKKLRGRSLHVLERALRDLPVPVLGRLDDDALWLDLRQLDDEAQWLAQLPALQLGPVQ	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: selenocysteine incorporation, translation, and selenocysteinyl-tRNA(Sec) biosynthetic process. This protein is located in the following component: cytoplasm. This protein is involved in metabolic process: selenocysteinyl-tRNA(Sec) biosynthetic process, and selenocysteine incorporation. This protein enables catalytic activity: catalytic activity. This protein is part of cytoplasm: cytoplasm. This protein enables transferase activity: L-seryl-tRNASec selenium transferase activity, and transferase activity. This protein is involved in translation: translation. This protein enables the following functions: catalytic activity, L-seryl-tRNASec selenium transferase activity, and transferase activity.
MAQRAFPNPYADYNKSLAENYFDSTGRLTPEFSHRLTNKIRELLQQMERGLKSADPQDGTGYTGWAGIAVLYLHLHNVFGDPAYLQMAHSYVKHSLNCLSRRSITFLCGDAGPLAVAAVLYHKMNSGKQAEDCITRLIHLNKIDPHVPNEMLYGRIGYIFALLFVNKNFGEEKIPQSHIQQICETILTSGEKLSRKRNFTTKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLHVSQGKLHSLVKPSVDFVCQLKFPSGNYPSCLDDTRDLLVHWCHGAPGVIYMLIQAYKVFKEEHYLCDAQQCADVIWQYGLLKKGYGLCHGAAGNAYAFLALYNLTQDAKYLYRACKFAEWCLDYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKAKFPAFEL	This protein is part of the following components: plasma membrane, membrane, and cytoplasm. This protein is involved in the following processs: regulation of oxidative stress-induced neuron death, carbohydrate metabolic process, and regulation of neuron apoptotic process. This protein is not involved in the following process: G protein-coupled receptor signaling pathway. This protein is not part of the following component: integral component of plasma membrane. This protein is active in the following component: plasma membrane. This protein is located in the following components: cytoplasm, plasma membrane, and membrane. This protein is not located in the following component: integral component of plasma membrane. This protein is involved in signal transduction: G protein-coupled receptor signaling pathway. This protein enables metal ion binding: zinc ion binding, and metal ion binding. This protein enables catalytic activity: catalytic activity. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of plasma membrane. This protein is part of cytoplasm: cytoplasm. This protein enables transferase activity: glutathione transferase activity, and transferase activity. This protein enables the following functions: catalytic activity, metal ion binding, SH3 domain binding, glutathione binding, zinc ion binding, transferase activity, glutathione transferase activity, and low-density lipoprotein particle receptor binding.
MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQALYAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIFYMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEVRPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIGFLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVASTVQEGVMRNHN	This protein is involved in the following processs: lipid metabolic process, and acyl-CoA metabolic process. This protein enables hydrolase activity: acyl-CoA hydrolase activity, and hydrolase activity. This protein is involved in metabolic process: acyl-CoA metabolic process. This protein enables the following functions: palmitoyl-CoA hydrolase activity, hydrolase activity, myristoyl-CoA hydrolase activity, and acyl-CoA hydrolase activity.
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDFRSGSPSDNSGAEEMEVALAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA	This protein is part of the following components: cytosol, cytoplasm, ciliary basal body, microtubule cytoskeleton, cell-cell junction, protein-containing complex, nucleus, vesicle, mitochondrion, plasma membrane, spindle, nucleoplasm, and membrane. This protein is involved in the following processs: cellular response to peptide, response to ischemia, carbohydrate transport, protein kinase B signaling, positive regulation of protein localization to nucleus, positive regulation of apoptotic process, phosphorylation, positive regulation of glucose import, negative regulation of cell size, hyaluronan metabolic process, positive regulation of transcription by RNA polymerase II, negative regulation of proteolysis, positive regulation of G1/S transition of mitotic cell cycle, regulation of glycogen biosynthetic process, protein catabolic process, response to oxidative stress, positive regulation of endothelial cell migration, insulin-like growth factor receptor signaling pathway, positive regulation of protein localization to cell surface, regulation of neuron projection development, maternal placenta development, response to hormone, negative regulation of release of cytochrome c from mitochondria, positive regulation of peptidyl-serine phosphorylation, negative regulation of intrinsic apoptotic signaling pathway, positive regulation of endodeoxyribonuclease activity, negative regulation of lymphocyte migration, regulation of protein localization, striated muscle cell differentiation, positive regulation of protein localization to plasma membrane, labyrinthine layer blood vessel development, insulin receptor signaling pathway, execution phase of apoptosis, regulation of aerobic respiration, cellular response to DNA damage stimulus, positive regulation of nitric-oxide synthase activity, positive regulation of gene expression, germ cell development, cellular response to granulocyte macrophage colony-stimulating factor stimulus, peptidyl-serine phosphorylation, negative regulation of fatty acid beta-oxidation, positive regulation of I-kappaB phosphorylation, epidermal growth factor receptor signaling pathway, positive regulation of DNA-binding transcription factor activity, peripheral nervous system myelin maintenance, protein phosphorylation, response to insulin-like growth factor stimulus, positive regulation of glycogen biosynthetic process, spinal cord development, cellular response to vascular endothelial growth factor stimulus, positive regulation of cellular protein metabolic process, positive regulation of cell population proliferation, response to fluid shear stress, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, cellular response to hypoxia, translation, positive regulation of nitric oxide biosynthetic process, intracellular signal transduction, negative regulation of calcium import into the mitochondrion, cellular response to nerve growth factor stimulus, positive regulation of protein phosphorylation, NIK/NF-kappaB signaling, signal transduction, regulation of translation, sphingosine-1-phosphate receptor signaling pathway, response to growth factor, protein import into nucleus, nervous system development, activation-induced cell death of T cells, cellular response to growth factor stimulus, maintenance of protein location in mitochondrion, cellular response to decreased oxygen levels, carbohydrate metabolic process, cellular response to prostaglandin E stimulus, positive regulation of glucose metabolic process, negative regulation of superoxide anion generation, cellular response to insulin stimulus, negative regulation of apoptotic process, negative regulation of protein kinase activity, positive regulation of endothelial cell proliferation, glucose homeostasis, positive regulation of blood vessel endothelial cell migration, positive regulation of fat cell differentiation, regulation of cell migration, positive regulation of organ growth, gene expression, osteoblast differentiation, cellular response to reactive oxygen species, response to growth hormone, negative regulation of long-chain fatty acid import across plasma membrane, apoptotic mitochondrial changes, peptidyl-threonine phosphorylation, cellular response to oxidised low-density lipoprotein particle stimulus, glycogen metabolic process, cellular response to cadmium ion, cell migration involved in sprouting angiogenesis, cellular response to organic cyclic compound, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of myelination, cell projection organization, glycogen cell differentiation involved in embryonic placenta development, positive regulation of fibroblast migration, glucose metabolic process, negative regulation of protein ubiquitination, cellular response to mechanical stimulus, establishment of protein localization to mitochondrion, positive regulation of sodium ion transport, glycogen biosynthetic process, cellular response to epidermal growth factor stimulus, aging, apoptotic process, response to food, inflammatory response, I-kappaB kinase/NF-kappaB signaling, lipopolysaccharide-mediated signaling pathway, positive regulation of vasoconstriction, negative regulation of autophagy, negative regulation of endopeptidase activity, multicellular organism development, positive regulation of mitochondrial membrane potential, response to UV-A, positive regulation of cyclin-dependent protein serine/threonine kinase activity, protein ubiquitination, positive regulation of smooth muscle cell proliferation, response to organic substance, negative regulation of leukocyte cell-cell adhesion, phosphatidylinositol 3-kinase signaling, regulation of apoptotic process, positive regulation of lipid biosynthetic process, negative regulation of JNK cascade, cellular response to tumor necrosis factor, interleukin-18-mediated signaling pathway, negative regulation of protein binding, positive regulation of transcription, DNA-templated, negative regulation of gene expression, and positive regulation of cell growth. This protein is located in the following components: microtubule cytoskeleton, mitochondrion, nucleoplasm, ciliary basal body, membrane, nucleus, cytoplasm, cytosol, spindle, plasma membrane, cell-cell junction, and vesicle. This protein is involved in signal transduction: phosphatidylinositol 3-kinase signaling, signal transduction, insulin receptor signaling pathway, lipopolysaccharide-mediated signaling pathway, interleukin-18-mediated signaling pathway, NIK/NF-kappaB signaling, insulin-like growth factor receptor signaling pathway, I-kappaB kinase/NF-kappaB signaling, protein kinase B signaling, epidermal growth factor receptor signaling pathway, and intracellular signal transduction. This protein is involved in metabolic process: protein catabolic process, hyaluronan metabolic process, and protein ubiquitination. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of membrane: plasma membrane, and membrane. This protein is involved in cellular response to DNA damage stimulus: cellular response to DNA damage stimulus. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables transferase activity: protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine/tyrosine kinase activity, transferase activity, and kinase activity. This protein is part of cytosol: cytosol. This protein is involved in carbohydrate metabolic process: glycogen biosynthetic process, glycogen metabolic process, carbohydrate metabolic process, and glucose metabolic process. This protein is involved in regulation of transcription, DNA-templated: positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, and positive regulation of DNA-binding transcription factor activity. This protein is involved in phosphorylation: peptidyl-threonine phosphorylation, protein phosphorylation, phosphorylation, and peptidyl-serine phosphorylation. This protein is involved in protein transport: protein import into nucleus. This protein is involved in translation: translation. This protein enables the following functions: protein homodimerization activity, ATP binding, protein serine/threonine kinase activity, protein binding, protein threonine kinase activity, protein kinase C binding, phosphatidylinositol-3,4-bisphosphate binding, potassium channel activator activity, 14-3-3 protein binding, kinase activity, protein phosphatase 2A binding, protein serine/threonine/tyrosine kinase activity, protein kinase activity, transferase activity, nitric-oxide synthase regulator activity, GTPase activating protein binding, enzyme binding, calmodulin binding, nucleotide binding, phosphatidylinositol-3,4,5-trisphosphate binding, protein serine kinase activity, protein kinase binding, and identical protein binding.
MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK	This protein is part of the following components: microvillus, integral component of plasma membrane, membrane, plasma membrane, integral component of membrane, and apical plasma membrane. This protein is involved in the following processs: transmembrane transport, response to bacterium, ion transport, sodium ion transport, and bile acid and bile salt transport. This protein is active in the following component: apical plasma membrane. This protein is located in the following components: apical plasma membrane, plasma membrane, integral component of membrane, membrane, and integral component of plasma membrane. This protein is part of membrane: membrane, plasma membrane, and apical plasma membrane. This protein is part of integral component of membrane: integral component of membrane, and integral component of plasma membrane. This protein is involved in transmembrane transport: transmembrane transport. This protein is involved in cation transport: bile acid and bile salt transport, ion transport, and sodium ion transport. This protein enables the following functions: symporter activity, protein binding, and bile acid.
MPSRRRTLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVQFEDRLFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNSAKSFEDLNNWREEFLIQASPSDPENFPFVVIGNKIDVDGGSSRVVSEKKARAWCASKGNIPYYETSAKVGTNVEDAFLCITTNAMKSGEEEEMYLPDTIDVGTSNPQRSTGCEC	This protein is part of the following components: Golgi apparatus, endomembrane system, nucleus, vacuolar membrane, membrane, and plasma membrane. This protein is involved in the following processs: response to oxidative stress, protein transport, and response to salt stress. This protein is active in the following component: vacuolar membrane. This protein is located in the following components: nucleus, Golgi apparatus, vacuolar membrane, plasma membrane, and membrane. This protein enables hydrolase activity: GTPase activity. This protein is involved in signal transduction: Rab protein signal transduction. This protein enables nucleotide binding: nucleotide binding, and GTP binding. This protein is part of membrane: vacuolar membrane, membrane, and plasma membrane. This protein is part of nucleus: nucleus. This protein is involved in protein transport: intracellular protein transport, and protein transport. This protein enables the following functions: GTPase activity, GTP binding, and nucleotide binding.
MELLSGPHAFLLLLLQVCWLRSVVSEPYRAGFIGEAGVTLEVEGTDLEPSQVLGKVALAGQGMHHADNGDIIMLTRGTVQGGKDAMHSPPTRILRRRKREWVMPPIFVPENGKGPFPQRLNQLKSNKDRGTKIFYSITGPGADSPPEGVFTIEKESGWLLLHMPLDREKIVKYELYGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVLEGVMPGTSVMQVTATDEDDAVNTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYRLTVQATDMDGEGSTTTAEAVVQILDANDNAPEFEPQKYEAWVPENEVGHEVQRLTVTDLDVPNSPAWRATYHIVGGDDGDHFTITTHPETNQGVLTTKKGLDFEAQDQHTLYVEVTNEAPFAVKLPTATATVVVHVKDVNEAPVFVPPSKVIEAQEGISIGELVCIYTAQDPDKEDQKISYTISRDPANWLAVDPDSGQITAAGILDREDEQFVKNNVYEVMVLATDSGNPPTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSDIYWMAEVSEKGDTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHGQVFNDCPRPWKGGFILPILGAVLALLTLLLALLLLVRKKRKVKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVVPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLVFDYEGSGSDAASLSSLTTSASDQDQDYNYLNEWGSRFKKLADMYGGGEDD	This protein is part of the following components: adherens junction, integral component of membrane, plasma membrane, membrane, cytoplasm, catenin complex, cell junction, and cell surface. This protein is involved in the following processs: positive regulation of monophenol monooxygenase activity, cell-cell adhesion, negative regulation of transforming growth factor beta2 production, positive regulation of melanosome transport, cell-cell adhesion mediated by cadherin, cell-cell adhesion via plasma-membrane adhesion molecules, positive regulation of keratinocyte proliferation, regulation of hair cycle by canonical Wnt signaling pathway, response to drug, cell morphogenesis, wound healing, cell-cell junction assembly, keratinization, adherens junction organization, positive regulation of canonical Wnt signaling pathway, calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, positive regulation of melanin biosynthetic process, multicellular organism development, hair cycle process, positive regulation of insulin-like growth factor receptor signaling pathway, retina homeostasis, negative regulation of timing of catagen, homophilic cell adhesion via plasma membrane adhesion molecules, cell adhesion, and positive regulation of gene expression. This protein acts upstream of or within the following processs: positive regulation of monophenol monooxygenase activity, negative regulation of transforming growth factor beta2 production, positive regulation of keratinocyte proliferation, keratinization, positive regulation of gene expression, positive regulation of insulin-like growth factor receptor signaling pathway, hair cycle process, regulation of hair cycle by canonical Wnt signaling pathway, retina homeostasis, positive regulation of canonical Wnt signaling pathway, positive regulation of melanosome transport, cell-cell adhesion, negative regulation of timing of catagen, and positive regulation of melanin biosynthetic process. This protein is active in the following component: cytoplasm. This protein is located in the following components: cytoplasm, integral component of membrane, adherens junction, membrane, cell junction, and plasma membrane. This protein is involved in signal transduction: regulation of hair cycle by canonical Wnt signaling pathway. This protein enables metal ion binding: metal ion binding, and calcium ion binding. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: metal ion binding, cadherin binding, calcium ion binding, and cytoskeletal protein binding.
MMMMSLNSKQAFSMPHAGSLHVEPKYSALHSASPGSSAPAAPSASSPSSSSNAGSGGGGGGGGGGGGGGRSSSSSSSGSGGGGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSHHHHPPHHSPFKPDATYHTMNTIPCTSAASSSSVPISHPSALAGTHHHHHHHHHHHHQPHQALEGELLEHLSPGLALGAMAGPDGTVVSTPAHAPHMATMNPMHQAALSMAHAHGLPSHMGCMSDVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSAGI	This protein is part of the following components: cytoplasm, nuclear speck, transcription regulator complex, cellular_component, nucleus, and euchromatin. This protein is involved in the following processs: neuron differentiation, negative regulation of transcription by RNA polymerase II, sensory perception of sound, axon guidance, positive regulation of osteoclast differentiation, regulation of transcription, DNA-templated, positive regulation of transcription regulatory region DNA binding, negative regulation of amacrine cell differentiation, positive regulation of cell differentiation, retina development in camera-type eye, positive regulation of axon extension, positive regulation of programmed cell death, multicellular organism development, intracellular estrogen receptor signaling pathway, positive regulation of transcription by RNA polymerase II, cellular response to cytokine stimulus, apoptotic process, cellular response to estradiol stimulus, positive regulation of glucose import, regulation of transcription by RNA polymerase II, regulation of DNA-binding transcription factor activity, neuromuscular process controlling balance, negative regulation of adipose tissue development, regulation of retinal ganglion cell axon guidance, dorsal root ganglion development, negative regulation of cell differentiation, intrinsic apoptotic signaling pathway by p53 class mediator, positive regulation of cardiac muscle cell apoptotic process, cellular response to oxygen levels, spermatogenesis, retinal ganglion cell axon guidance, regulation of gene expression, negative regulation of DNA-binding transcription factor activity, axon extension, MAPK cascade, heart development, cellular response to insulin stimulus, axonogenesis, and cell differentiation. This protein is active in the following component: cellular_component. This protein is located in the following components: nuclear speck, cytoplasm, nucleus, and euchromatin. This protein is involved in signal transduction: intracellular estrogen receptor signaling pathway, MAPK cascade, and intrinsic apoptotic signaling pathway by p53 class mediator. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA binding, and sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: negative regulation of DNA-binding transcription factor activity, positive regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, negative regulation of transcription by RNA polymerase II, and regulation of DNA-binding transcription factor activity. This protein enables the following functions: DNA-binding transcription activator activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA binding, p53 binding, sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription factor activity, transcription coactivator activity, chromatin binding, molecular_function, DNA-binding transcription repressor activity, RNA polymerase II-specific, promoter-specific chromatin binding, and transcription corepressor activity.
MASQSKTSVHDFTVKDAKGQDVDLSIYKGKLLLIVNVASQCGLTNSNYTELSQLYDKYKNQGLEILAFPCNQFGAQEPGDNEQIQEFACTRFKAEFPIFDKVDVNGDNAAPLYKHLKSSKGGLFGDSIKWNFSKFLVDKEGNVVERYAPTTSPLSIEKDIKKLLETA	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: response to oxidative stress, and cellular oxidant detoxification. This protein is located in the following component: cytoplasm. This protein enables catalytic activity: oxidoreductase activity, glutathione peroxidase activity, peroxidase activity, and phospholipid-hydroperoxide glutathione peroxidase activity. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: oxidoreductase activity, glutathione peroxidase activity, peroxidase activity, and phospholipid-hydroperoxide glutathione peroxidase activity.
MTLDNLKHSAILSTLFKMADDNDLLGASEFIKDRLYFATLRSKPKSTANTHYFSTDEEFVYENFYADFGPLNLAMLYRYCCKLNKKLKSFTLTRKRIVHYTSFDQRKRANAAVLIGAYAVIYLKKTPEEAYRALISGSNASYLPFRDASFGNCTYNLTVLDCLQGIRKALQHGFLNFETFDVNEYEHYERVENGDLNWITPGKLLAFSGPHPKSKVENGYPLHAPEAYFPYFRKHNVTTIVRLNKKIYDAKRFTDAGFDHYDLFFVDGSTPSDIITRRFLHICESTSGAVAVHCKAGLGRTGTLIGCYLMKHYRFTSAEAIAWIRICRPGSIIGPQQHYLEEKQASLWAHGDSLRSKQRQYQDRSVPQLISSMDNLSISTSIFKSHSLDRMEENDYAENDLGMTQGDKLRALKGRRQPRSATTGAIRVEDVKVHTRSPSQPLSRMKPPASSQGSISPLKSSKVPASSSSSSSSSSVSASAKRIGRSSSSSTNLKSTRLASSLGNLYEPNTESISSGKPPSPSSFTPHPVRTTYNYHYEVNNNNNQYSTTSSPSKSLGYNLNHSGPSGASANARLSAGEQGHQRNPPAGLSGLSTRHLSRSIPSLQSEYVQY	This protein is part of the following components: spindle pole, kinociliary basal body, cytoplasm, centrosome, microtubule organizing center, nucleus, nucleolus, mitotic spindle, spindle, cell projection, kinocilium, and cytoskeleton. This protein is involved in the following processs: cell division, positive regulation of cytokinesis, protein dephosphorylation, regulation of cell cycle, regulation of cell cycle, cilium assembly, mitotic cell cycle, microtubule cytoskeleton organization, regulation of exit from mitosis, peptidyl-tyrosine dephosphorylation, cell cycle, and dephosphorylation. This protein is active in the following components: kinociliary basal body, nucleolus, spindle pole, cytoplasm, centrosome, and mitotic spindle. This protein is located in the following components: microtubule organizing center, spindle, cytoskeleton, nucleus, spindle pole, kinocilium, cell projection, and cytoplasm. This protein enables hydrolase activity: protein tyrosine phosphatase activity, protein serine/threonine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity, phosphoprotein phosphatase activity, hydrolase activity, and phosphatase activity. This protein is involved in metabolic process: peptidyl-tyrosine dephosphorylation, protein dephosphorylation, and dephosphorylation. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is involved in cell cycle: cell cycle, and mitotic cell cycle. This protein is involved in cell division: cell division. This protein enables the following functions: protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, phosphoprotein phosphatase activity, hydrolase activity, protein threonine phosphatase activity, protein serine phosphatase activity, phosphatase activity, and protein tyrosine/serine/threonine phosphatase activity.
MSSWTSKENINGVYIPSALLIFGTTIIKKEWIAYATALAVVLSAWKLFSNKPRKVLNPTEFQNFVLKDKTIVSHNVCIYRFALPRPTDILGLPIGQHISLAATIPGQSKEIVRSYTPISSDDDAGYFDLLVKSYPQGNISKHLTTLRIGDKMKVRGPKGAMVYTPNMVRHIGMIAGGTGITPMLQVIKAIIKGRPRNGGNDTTQIDLIFANVNPDDILLKEELDQLAKEDDAFRIYYVLNNPPEKWNGGVGFVTPDMIKAKLPAPAGDIKVLICGPPPMVSAMKKATESLGYKKANLVSKLEDQVFCF	This protein is part of the following components: mitochondrial outer membrane, mitochondrion, integral component of membrane, membrane, endoplasmic reticulum, and endoplasmic reticulum membrane. This protein is located in the following components: integral component of membrane, mitochondrial outer membrane, endoplasmic reticulum, endoplasmic reticulum membrane, mitochondrion, and membrane. This protein enables catalytic activity: oxidoreductase activity, and cytochrome-b5 reductase activity, acting on NAD(P)H. This protein is part of membrane: membrane, endoplasmic reticulum membrane, and mitochondrial outer membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of mitochondrion: mitochondrion. This protein enables the following functions: oxidoreductase activity, and cytochrome-b5 reductase activity, acting on NAD(P)H.
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEVVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDISTKLPSKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGGPTRMEGNLPAKLRKMNSDRFT	This protein is part of the following components: integral component of membrane, external side of plasma membrane, parallel fiber to Purkinje cell synapse, T-tubule, cell surface, plasma membrane, membrane, integral component of presynaptic membrane, and voltage-gated potassium channel complex. This protein is involved in the following processs: potassium ion transport, response to electrical stimulus, potassium ion import across plasma membrane, regulation of ion transmembrane transport, and ion transport. This protein acts upstream of or within the following process: potassium ion import across plasma membrane. This protein contributes to the following function: inward rectifier potassium channel activity. This protein is active in the following component: plasma membrane. This protein is located in the following components: parallel fiber to Purkinje cell synapse, cell surface, T-tubule, external side of plasma membrane, integral component of presynaptic membrane, membrane, and integral component of membrane. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of presynaptic membrane, and integral component of membrane. This protein is involved in cation transport: ion transport, potassium ion import across plasma membrane, and potassium ion transport. This protein enables the following functions: voltage-gated ion channel activity, G-protein activated inward rectifier potassium channel activity, and inward rectifier potassium channel activity.
MENNEEFQDELLALESIYPSCLLPISEQSFTYTLSIPDSSVRLNIQFPLDYPNSAPTVLDAYGIDKTLAEDVLLSVATGDVCIFSYMDLLKELVDIDAEQAAAERESKLQEESDKETPVMLNKSHYVAKTPEIQDEPWKPKFDWKESEPITDRKSTFMAHATRVYSTEEVREALEDLYMDKKVAKANHNMVAYRIISPNGNVIQDNDDDGESAAGSRMSHLLTMMSAENVFVCVSRWFGGVHIGPDRFKHINSSAREAVLLTDAAPSQKKGTEHGKKKKK	This protein is part of the following components: cytoplasm, polysome, and nucleus. This protein is involved in the following processs: GCN2-mediated signaling, regulation of translation, cellular response to amino acid starvation, regulation of cytoplasmic translation in response to stress, negative regulation of protein phosphorylation, negative regulation of cell death, positive regulation of translational initiation in response to starvation, regulation of translational initiation, negative regulation of protein kinase activity, regulation of cytoplasmic translational initiation in response to stress, cellular response to acidic pH, cellular response to benomyl, and cellular response to hydrogen peroxide. This protein is located in the following components: cytoplasm, and nucleus. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables the following functions: actin binding, protein kinase inhibitor activity, polysome binding, and ribosome binding.
MSKVFKKTSSNGKLSIYLGKRDFVDHVDTVEPIDGVVLVDPEYLKCRKLFVMLTCAFRYGRDDLEVIGLTFRKDLYVQTLQVVPAESSSPQGPLTVLQERLLHKLGDNAYPFTLQMVTNLPCSVTLQPGPEDAGKPCGIDFEVKSFCAENPEETVSKRDYVRLVVRKVQFAPPEAGPGPSAQTIRRFLLSAQPLQLQAWMDREVHYHGEPISVNVSINNCTNKVIKKIKISVDQITDVVLYSLDKYTKTVFIQEFTETVAANSSFSQSFAVTPILAASCQKRGLALDGKLKHEDTNLASSTIIRPGMDKELLGILVSYKVRVNLMVSCGGILGDLTASDVGVELPLVLIHPKPSHEAASSEDIVIEEFTRKGEEESQKAVEAEGDEGS	This protein is part of the following components: photoreceptor inner segment, cell projection, synapse, photoreceptor outer segment, and cytoplasm. This protein is involved in the following processs: signal transduction, regulation of protein phosphorylation, visual perception, G protein-coupled receptor internalization, endocytosis, and response to stimulus. This protein is located in the following components: photoreceptor outer segment, synapse, cell projection, cytoplasm, and photoreceptor inner segment. This protein is involved in signal transduction: signal transduction. This protein is involved in metabolic process: G protein-coupled receptor internalization. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: phosphoprotein binding, opsin binding, G protein-coupled receptor binding, and protein binding.
ASINYTYIIYVIGVITILYASFSTLRTIDIKELIAYSSVSHAAVYLIGAFSNTIQGIEGSIALGLAHGFVSSGLFICAGGILYDRSSTRLITYYRGMAQIMPIFSVLFFILALGNSGTPLTLNFIGEFMSLYGVFERMPILGVLASTSIVFSAAYTIFMYNRIVFGGSYSIYFRENIGDVTRREFIMLLVFVILTVLFGIYPAPILDGLHYSVSYLIYNIN	This protein is part of the following components: membrane, mitochondrion, integral component of membrane, mitochondrial membrane, and respirasome. This protein is involved in the following process: ATP synthesis coupled electron transport. This protein is located in the following components: membrane, integral component of membrane, respirasome, mitochondrial membrane, and mitochondrion. This protein is involved in metabolic process: ATP synthesis coupled electron transport. This protein enables catalytic activity: NADH dehydrogenase (ubiquinone) activity. This protein is part of membrane: membrane, and mitochondrial membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of mitochondrion: mitochondrion. This protein enables the following function: NADH dehydrogenase (ubiquinone) activity.
MVLVTQNAPNFIAPAILKNNQIVEQFDLKKYSNGQSTVLFFWPMDFTFVCPSEIIEFNKLHSEFKKRNVKIVGVSIDSVYVHQAWQNTLPKNGGIGKINFPMVSDVKHDIQKSYGIQHPNLGIALRASFLIDSNWIIRHQVVNDLPFGRNITDMIRMVDALDFHNKFGEVCPANWKKGEEGITASSEGVSQYLSKYS	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: cellular oxidant detoxification, and cell redox homeostasis. This protein is located in the following component: cytoplasm. This protein enables catalytic activity: oxidoreductase activity, peroxiredoxin activity, and peroxidase activity. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: alkylhydroperoxide reductase activity, oxidoreductase activity, peroxidase activity, antioxidant activity, and peroxiredoxin activity.
MATQQRPFHLVVFGASGFTGQFVTEEVAREQVSPERTSHLPWAVAGRSREKLLRVLERAAMKLGRPTLSSEVGIIICDITNPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGTSCIDISGEPQFLELMYWKYHEKAAEKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESFLTISSGPEGLCVHDGTWKSAVYGFGDKSNLKKLRNESDMKPVPIVGPKLKRRWPISYCRELNSYSIPFLGADVSVVKRTQRYLHENLEQSPVQYAAYINVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFTWLFSFGYFSKQGPTQKQIDASSFTMTFFGQGFSQGVSPVKNKPNIRICTQVKGPEAGYVSTSIAMVQAAMILLNDASDLPKAGGVFTPGAAFSRTKLIDRLNEHGIEFSVISSTEV	This protein is part of the following component: lipid droplet. This protein enables catalytic activity: oxidoreductase activity. This protein is part of membrane: plasma membrane. This protein is part of mitochondrion: mitochondrion. This protein is involved in lipid metabolic process: glycolipid biosynthetic process. This protein enables the following function: oxidoreductase activity.
ISGKELQEMSTEGSKYVNKEIKNALKEVLQIKLVMEQGREQSSVMNVMPFPLLEPLNFHDVFQPFY	This protein is part of the following components: chromaffin granule, mitochondrial inner membrane, mitochondrion, perinuclear region of cytoplasm, cytoplasm, intracellular membrane-bounded organelle, perinuclear endoplasmic reticulum lumen, membrane, mitochondrial membrane, endoplasmic reticulum, cytosol, nucleus, extracellular region, and cytoplasmic vesicle. This protein is involved in the following processs: positive regulation of receptor-mediated endocytosis, regulation of cell population proliferation, positive regulation of apoptotic process, negative regulation of amyloid fibril formation, immune complex clearance, and protein stabilization. This protein is located in the following components: extracellular region, cytoplasm, cytoplasmic vesicle, nucleus, perinuclear endoplasmic reticulum lumen, mitochondrial inner membrane, chromaffin granule, intracellular membrane-bounded organelle, perinuclear region of cytoplasm, cytosol, membrane, mitochondrial membrane, mitochondrion, and endoplasmic reticulum. This protein is part of membrane: mitochondrial inner membrane, mitochondrial membrane, and membrane. This protein is part of mitochondrion: mitochondrion. This protein is part of extracellular region: extracellular region. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein enables the following function: unfolded protein binding.
MPCLFIFIALLLSSCIGTLKALDQTCGNKVVNTIVVDQAGSGEGQRVTTITYNGHAATDVSSTFTSYPSHIVVRNLSIMNTYNRLTSLTKANGMSWDIKPAVAISVYGDKSAFYNCDFLGLQDTVWDNLGRHHFKNCYIEGAIDFIFGSGQSVYEDCHINATAGALASKVSFGYITAQGRSSDSDPSGFVFLRGSVSGSTSVYLGRAYGPFSRVIFIQTDLSSVVHPEGWYSWHYGGYEMSFTYAEVECKGAGSDMSRRVPWIDKLHSFYTKQQFSISNFIDQDQWISNIPRF	This protein is part of the following components: cell wall, and extracellular region. This protein is involved in the following processs: cell wall modification, cell wall organization, and pectin catabolic process. This protein is located in the following components: extracellular region, and cell wall. This protein enables hydrolase activity: pectinesterase activity, carboxylic ester hydrolase activity, aspartyl esterase activity, and hydrolase activity. This protein is part of extracellular region: extracellular region. This protein is involved in carbohydrate metabolic process: pectin catabolic process. This protein enables the following functions: hydrolase activity, pectinesterase activity, aspartyl esterase activity, and carboxylic ester hydrolase activity.
MYRARAARAGPEPGSPGRFGILSTGQLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRAALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLSPRPSQPEPPHR	This protein is part of the following components: late endosome membrane, extracellular exosome, membrane, endosome membrane, host cell, ESCRT I complex, intracellular membrane-bounded organelle, and endosome. This protein is involved in the following processs: protein transport, endosomal transport, endosome transport via multivesicular body sorting pathway, macroautophagy, protein targeting to vacuole, viral life cycle, multivesicular body assembly, protein targeting to membrane, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, intracellular transport of virus, and viral budding via host ESCRT complex. This protein is active in the following component: intracellular membrane-bounded organelle. This protein is located in the following components: endosome membrane, membrane, late endosome membrane, endosome, extracellular exosome, and host cell. This protein is involved in metabolic process: macroautophagy. This protein is part of membrane: endosome membrane, membrane, and late endosome membrane. This protein is involved in proteolysis: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. This protein is involved in protein transport: protein targeting to membrane, protein targeting to vacuole, and protein transport. This protein enables the following function: protein binding.
METEAADESGFTSVASKRGRRKRRAAGAEPMEAAESAEAAGPQPSKRPAFPPLPAAALGVGKGEVRKVPVPANRYTPLKENWMKIFTPIVEHLQLQIRFNLKTRNVEIKTCSETKDLSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEVTDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADSKIHILGSFQNIKMARTAICNLILGSPPSKVYGNIRAVASRAAERF	This protein is part of the following components: nucleoplasm, nucleolus, and nucleus. This protein is active in the following component: nucleolus. This protein is located in the following components: nucleus, nucleolus, and nucleoplasm. This protein enables RNA binding: RNA binding. This protein is part of nucleus: nucleus. This protein enables the following functions: RNA binding, and nucleic acid binding.
MDLSSRLSSGSSRIPKRHRDYRDEEPRRERGSGGIGREDPRGHYGSERPRRRRRDESDFRRHRESRERSYREDERPRRERRYDDYEPRSLRYSSVGRSRSPPPSRERSVRSIEQELEQLRDVTPINQWKRKRSLWDIKPPGYELVTADQAKMSGVFPLPGAPRAAVTDPEKLLEFARSAEGSIIAPPPPLQPGASRQARRLVVTGIPNEFVEDAFVSFIEDLFISTTYHKPETKHFSSVNVCKEENFAILEVATPEDATFLWGLQSESYSNDVFLKFQRIQNYIVPQITPEVSQKRSDDYAKNDVLDSKDKIYISNLPLNLGEDQVVELLKPFGDLLSFQLIKNIADGSSKGFCFCEFKNPSDAEVAISGLDGKDTYGNKLHAQFACVGLNQAMIDKSNGMAILTELAKASSQSIPTRVLQLHNLITGDEIMDVQEYEDIYESVKTQFSNYGPLIDIKIPRSIGTRNSGLGTGKVFVRYSDIRSAEVAMEEMKGCKFNDRTIVIAFYGEDCYKANAW	This protein is part of the following components: U2-type prespliceosome, commitment complex, nucleus, U2AF complex, and nuclear speck. This protein is involved in the following processs: RNA splicing, mRNA processing, mRNA cis splicing, via spliceosome, spliceosomal complex assembly, and mRNA branch site recognition. This protein is active in the following component: nuclear speck. This protein is located in the following component: nucleus. This protein is involved in metabolic process: RNA splicing, mRNA cis splicing, via spliceosome, and mRNA processing. This protein enables RNA binding: poly-pyrimidine tract binding, mRNA binding, RNA binding, and pre-mRNA 3'-splice site binding. This protein is part of nucleus: nucleus. This protein enables the following functions: pre-mRNA 3'-splice site binding, mRNA binding, RNA binding, nucleic acid binding, poly-pyrimidine tract binding, and protein binding.
MKRIPIKELIVEHPGKVLILDGGQGTELENRGININSPVWSAAPFTSESFWEPSSQERKVVEEMYRDFMIAGANILMTITYQANFQSISENTSIKTLAAYKRFLDKIVSFTREFIGEERYLIGSIGPWAAHVSCEYTGDYGPHPENIDYYGFFKPQLENFNQNRDIDLIGFETIPNFHELKAILSWDEDIISKPFYIGLSVDDNSLLRDGTTLEEISVHIKGLGNKINKNLLLMGVNCVSFNQSALILKMLHEHLPGMPLLVYPNSGEIYNPKEKTWHRPTNKLDDWETTVKKFVDNGARIIGGCCRTSPKDIAEIASAVDKYS	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: methionine biosynthetic process, cellular amino acid biosynthetic process, methylation, and sulfur amino acid metabolic process. This protein is located in the following component: cytoplasm. This protein is involved in metabolic process: sulfur amino acid metabolic process. This protein enables metal ion binding: metal ion binding, and zinc ion binding. This protein is part of cytoplasm: cytoplasm. This protein enables transferase activity: transferase activity, S-adenosylmethionine-homocysteine S-methyltransferase activity, methyltransferase activity, and betaine-homocysteine S-methyltransferase activity. This protein is involved in methylation: methylation. This protein is involved in cellular amino acid biosynthetic process: cellular amino acid biosynthetic process, and methionine biosynthetic process. This protein enables the following functions: transferase activity, S-methylmethionine-homocysteine S-methyltransferase activity, zinc ion binding, methyltransferase activity, betaine-homocysteine S-methyltransferase activity, S-adenosylmethionine-homocysteine S-methyltransferase activity, and metal ion binding.
MKPDTVSLTRAFSKATSTSSKAALSWLKKYNFDYDVAYTKWIQQKSREEAEKQLNNVFSQFSSKEDKDLIELDGSVQLFTALDISLEDPETLLVSYFLKSPRMGEFHRESFVEGALNLSTTSLDQLKLAIKEKVQVWRSDASLQKAIYIYTYPLACDKGKKTLSTSIAIEFFQILLKDTFPLLDDWIAFLKVSPIIEKSLPKDTWNELWDFSVFVKSDPNCSNYDFEGAWPTLIDEFVSYYREHGYKNSSS	This protein is part of the following components: cytosol, ubiquitin ligase complex, and nucleus. This protein is involved in the following processs: protein neddylation, and positive regulation of ubiquitin-protein transferase activity. This protein is located in the following components: nucleus, and cytosol. This protein is involved in metabolic process: protein neddylation. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein enables the following functions: molecular_function, cullin family protein binding, ubiquitin conjugating enzyme binding, and ubiquitin-like protein binding.
MSTFEKINKVSVVIPVYNEEESLPQLLERTIKSCKQLEQEYELILVDDGSSDNSAKMLEEAANIEDNHVIAIILNRNYGQHSAIMAGFNQADGDLVITLDADLQNPPEEIPRLVATAEEGYDVVGTRRRNRQDSWFRKTASKMINAMITKATGRSMGDYGCMLRAYRRHIIDAMLQCHERSTFIPILANTFARRTIEIEVAHAEREYGDSKYSFLKLINLMYDLLTCLTTAPLRLLSVVGSVIAVAGFLLAVLLIVLRLIFGAIWAADGVFTLFAILFMFIGAQFVAMGLLGEYIGRIYNDVRARPRYFIQKVVGVKKPNKNQEED	This protein is part of the following components: plasma membrane, membrane, and integral component of membrane. This protein is involved in the following processs: 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process, lipid A biosynthetic process, lipid metabolic process, response to antibiotic, and lipopolysaccharide biosynthetic process. This protein is located in the following components: membrane, integral component of membrane, and plasma membrane. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables transferase activity: undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity, glycosyltransferase activity, phosphotransferase activity, for other substituted phosphate groups, and transferase activity. This protein is involved in lipid metabolic process: lipid A biosynthetic process, lipid metabolic process, 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process, and lipopolysaccharide biosynthetic process. This protein enables the following functions: undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity, phosphotransferase activity, for other substituted phosphate groups, glycosyltransferase activity, and transferase activity.
MLTKRIIPCLDIKDGRVVKGTKFLNLRDAGDPVELAQYYDDEGADELVFLDITASAEKRDIIIDVVERTAEKVFIPLTVGGGIKSIEDFRRILRAGADKVSINTAAVKNPNLIKEASEIFGSQCVVVAIDAKRHYVNEDEIDKINKNVVKVEDGYCWFEVYIYGGRKETGIDAINWAKKVEELGAGEILLTSIDKDGTKSGYDLILTKEISKSVKLPVIASGGCGKPEHVYEAFVYGKADAALMAGILHYREYTIEEIKKYCADRGIPMRLL	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: histidine biosynthetic process, and cellular amino acid biosynthetic process. This protein is located in the following component: cytoplasm. This protein enables catalytic activity: catalytic activity, and lyase activity. This protein is part of cytoplasm: cytoplasm. This protein enables transferase activity: imidazoleglycerol-phosphate synthase activity. This protein is involved in cellular amino acid biosynthetic process: histidine biosynthetic process, and cellular amino acid biosynthetic process. This protein enables the following functions: imidazoleglycerol-phosphate synthase activity, catalytic activity, and lyase activity.
MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL	This protein is part of the following components: lysosome, cytosol, phagophore assembly site, PML body, nucleoplasm, nucleus, mitochondrion, endosome, P-body, amphisome, aggresome, autophagosome, endoplasmic reticulum, intracellular membrane-bounded organelle, sarcomere, cytoplasm, late endosome, autolysosome, extracellular exosome, inclusion body, sperm midpiece, Lewy body, and cytoplasmic vesicle. This protein is involved in the following processs: regulation of Ras protein signal transduction, endosomal transport, negative regulation of apoptotic process, pexophagy, cell differentiation, response to mitochondrial depolarisation, response to ischemia, macroautophagy, protein localization to perinuclear region of cytoplasm, positive regulation of transcription by RNA polymerase II, mitochondrion organization, autophagy, negative regulation of protein ubiquitination, aggrephagy, protein phosphorylation, selective autophagy, regulation of protein complex stability, negative regulation of transcription by RNA polymerase II, apoptotic process, endosome organization, regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of protein phosphorylation, interleukin-1-mediated signaling pathway, autophagy of mitochondrion, positive regulation of apoptotic process, positive regulation of protein localization to plasma membrane, ubiquitin-dependent protein catabolic process, regulation of mitochondrion organization, protein localization, immune system process, intracellular signal transduction, positive regulation of long-term synaptic potentiation, and mitophagy. This protein is active in the following components: amphisome, and aggresome. This protein is located in the following components: inclusion body, lysosome, autolysosome, PML body, Lewy body, amphisome, aggresome, sarcomere, P-body, nucleus, endoplasmic reticulum, nucleoplasm, cytosol, sperm midpiece, phagophore assembly site, autophagosome, extracellular exosome, endosome, mitochondrion, intracellular membrane-bounded organelle, cytoplasm, late endosome, and cytoplasmic vesicle. This protein is involved in signal transduction: intracellular signal transduction, and interleukin-1-mediated signaling pathway. This protein is involved in metabolic process: aggrephagy, autophagy, mitophagy, macroautophagy, selective autophagy, and autophagy of mitochondrion. This protein enables metal ion binding: zinc ion binding, and metal ion binding. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables transferase activity: protein serine/threonine kinase activity. This protein is involved in proteolysis: ubiquitin-dependent protein catabolic process. This protein is part of cytosol: cytosol. This protein is involved in regulation of transcription, DNA-templated: negative regulation of transcription by RNA polymerase II, and positive regulation of transcription by RNA polymerase II. This protein is involved in phosphorylation: protein phosphorylation. This protein enables the following functions: protein kinase C binding, SH2 domain binding, receptor tyrosine kinase binding, protein-containing complex binding, zinc ion binding, ionotropic glutamate receptor binding, ubiquitin binding, ubiquitin protein ligase binding, identical protein binding, K63-linked polyubiquitin modification-dependent protein binding, protein binding, metal ion binding, enzyme binding, protein kinase binding, and protein serine/threonine kinase activity.
MFDDPSKRLTYFEYAVGVLLCSWPVMKQAVEEEWADVDTADKRDWMAGVLVDYITVTSDVEAWDVEELILQVLQDEFNVGSIEDDSPYILAQDLVNVWKAACEDNYEPIREIHERLGKQLLEKEEGKEKTREESNPPVLVEDETIVDAEDGGAAQNQQEKQQGPIVDDDGFTVVQKRRR	This protein is part of the following components: nucleus, cytoplasm, and cytosol. This protein is involved in the following processs: maturation of SSU-rRNA, ribosome biogenesis, rRNA processing, and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). This protein is located in the following components: nucleus, cytoplasm, and cytosol. This protein is involved in metabolic process: rRNA processing, maturation of SSU-rRNA, and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein enables the following function: molecular_function.
MRVTNRSLKGREGEIAVTAETLDDLWHLKYIIEKGDLVFSVTKRKADSASDKIRPEKVEKVKVRLGIRVDDLEFHKFANRLRLHGMIERGMDVGSYHTLNIEIGTNLSVIKEHWKNDQLQRIKDAEEASKRPKVVMVAIEEGDADIGFVHHYGIEIYSHIRQSSGKRETGLRNEFFREVVEQLRHAVPEEASIVIAGPGFTKEDFIKYFQETEPAMASKALIEDTSMIGMSGFQEVLRRGAVDRIMQESRIARESALMEDLIREISMDGKAAYGLGDVKNALNFGAVETLLVADETLREGREKGEDIDKLLREVEQAQGKVVVFSTAFEPGEKLHKLGGIAALLRFKVRG	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: nucleic acid phosphodiester bond hydrolysis, nuclear-transcribed mRNA catabolic process, non-stop decay, RNA surveillance, and nuclear-transcribed mRNA catabolic process, no-go decay. This protein is located in the following component: cytoplasm. This protein enables hydrolase activity: nuclease activity, hydrolase activity, and endonuclease activity. This protein is involved in metabolic process: nuclear-transcribed mRNA catabolic process, non-stop decay, nucleic acid phosphodiester bond hydrolysis, nuclear-transcribed mRNA catabolic process, no-go decay, and RNA surveillance. This protein enables metal ion binding: metal ion binding. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: endonuclease activity, metal ion binding, hydrolase activity, and nuclease activity.
MMQQRSGSLSLLSNAVQAGQSSDPMQDDPAKTEPGTPKGYDGSKNSSPASVPSWIHEKTKAGKDRKRLPLACQSCRKKKVKCSGERPSCDQCLKHNIPCIYKSNSTKRSHSRHEEIHHQQQLHLNHQYQHQHKNVAANSIDNLSRQYSQPNHINTHDSVNSPPSYGIMASATNQPLSHPTIVPSSNSSSLLNSTNNISHNPQVSLMSASLSKNLVLDPASPKSVSPDLVYVSSDNPPVSTAASAYSSSLPISDVTRALPLAPASNSQHPSLSSQPVSVPSNTINIPTDSLSIVSNPSQTPAKFDSNRISQVPNSDYSIYSNFNNFPIANHAPSFPQSSVKKLDSSFSPTSLPTFTTNSASSGLSTSYTNNNDTTSDNNSLQAVPRLDPVPSLTLSSTPVAELPPLELRIHLAEVFFHCCHGQSYNLFHRPTFFESLNNNTVPLVVVYAVCAVSARFSSRMHDRFSPPYMAGEQYAREARRLALDNFDRPDLSLVAALLLLSLHDSGTCETGKSWMYGGMALRMAAALQLNCEQGSNPLDLDNIDSGPRISFLERELRRRTFWSCFLMDRYASSHEHLQFLDENDIGIQLPVHELLFTKQIAGVTQTLDGRILEGVPSIVIPADTTENMGVAAYTVKIIALWGRAVKYLKQDGKRRDPYPYWHRNSDFSHISEALYAWADGLPQRLKYSAVGLENHLSIQQGAQYAFLHLAYHHTLMWLFRSIGETENNQLSKISSSVSLAGNTVSFSPVSHTPINVTNGESQNNSNNDPSANGAARRLHKAAREICLRCANAISMIVDDCRKHNVILTSPFIASGVYTAFCVQAEAAFGSNVLAASTARHNLEIDLRLMLEMKNYWGSISALCDKMSEIWADWVQRTSSGIQEEDTIPNEMIDEERMLDLEKHFMYITESPIVPNQAAQKSYSPDLMSYFGFAKNSDLQQWNGLWPSDDLRNYQESTIDSLVAYATGNPGWNISFAG	This protein is part of the following components: host cell nucleus, nucleus, and cytoplasm. This protein is involved in the following processs: regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, and transcription, DNA-templated. This protein is located in the following components: nucleus, and cytoplasm. This protein is involved in metabolic process: transcription, DNA-templated. This protein enables metal ion binding: metal ion binding, and zinc ion binding. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: DNA binding, and RNA polymerase II cis-regulatory region sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: regulation of transcription, DNA-templated, and regulation of transcription by RNA polymerase II. This protein enables the following functions: DNA-binding transcription factor activity, RNA polymerase II-specific, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, zinc ion binding, and DNA binding.
MGRRFKFLQKLAFLGQNHRYKALERDEVDTLIDEQYELKAIEREKAVAALPPREACKCSKEELARTFHVDLDSGLSEFAVAQRRLVHGWNEFVTDNTEPVWKKYLDQFRNPLILLLLGSSVVSVLTKEYEDAISIALAVLIVVTVGFIQEYRSEKSLEELTKLVPPECNCLRDGKLRHMLARDLVPGDVVSLSMGDRIPADIRLTEVTDLLVDESSFTGEVEPCSKTDSPLAGGGDLSTLSNVVFMGTLVQCGKGQGVVIGTGEQSQFGEVFKMMRAEETPKTPLQKSMDKLGKQLTVFSFGIIGLLMLVGWVQGKPLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTATQLVTSDGFHAEVSGIGYSGEGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVVRKNAVMGQPTEGALVVLAMKMNLGSIKDSYIRKKEIPFSSEQKWMAVRCSLKNEDEEDVYFMKGAFEEVIHHCSTYNNGGIPLPLTPQQKSYCQQEEKKMGSLGLRVLALASGPELGRLTFLGLVGIIDPPRAGVKEAVQALSESDVSVKMVTGDALETALAIGRTIGLCDEKLKAMSGEEVEGMEQDALAARVRQVSVFFRTSPKHKVKIIKALQESGAIVAMTGDGVNDSVALKSADIGIAMGQTGTDVSKEAADMILVDDDFSAIMSAVEEGKGIFYNIKNFVRFQLSTSIAALSLITLSTVCNLPNPLNAMQILWVNIIMDGPPAQSLGVEPVDRDALKRPPRSVKDTILNRALILKILMSAAVILGGTLFIFWREIPENRTSTPRTTTMAFTCFVFFDLFNALSCRSQTKLIFEIGFFRNRMFLYSILGSLLGQLAVIYAPPLQKVFQTENLSALDLLLLTGLASSVFILSELLKLCEKFCSRAKADQMLPEAV	This protein is part of the following components: cytoplasmic vesicle, cellular_component, Golgi membrane, plasma membrane, integral component of membrane, perinuclear region of cytoplasm, cytoplasmic side of plasma membrane, membrane, and endoplasmic reticulum. This protein is involved in the following processs: manganese ion transmembrane transport, cellular calcium ion homeostasis, ion transport, calcium ion transport, positive regulation of calcium ion import, mammary gland epithelium development, manganese ion transport, protein localization to plasma membrane, proton transmembrane transport, calcium ion transmembrane transport, and biological_process. This protein is active in the following components: endoplasmic reticulum, cellular_component, plasma membrane, and Golgi membrane. This protein is located in the following components: cytoplasmic side of plasma membrane, integral component of membrane, membrane, cytoplasmic vesicle, perinuclear region of cytoplasm, and trans-Golgi network membrane. This protein enables hydrolase activity: ATP hydrolysis activity. This protein enables metal ion binding: metal ion binding. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of membrane: plasma membrane, Golgi membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in cation transport: calcium ion transmembrane transport, manganese ion transmembrane transport, proton transmembrane transport, manganese ion transport, calcium ion transport, and ion transport. This protein enables the following functions: nucleotide binding, ABC-type manganese transporter activity, molecular_function, metal ion binding, ATP hydrolysis activity, ATP binding, P-type proton-exporting transporter activity, and P-type calcium transporter activity.
MASLIYRQLLANSYAVDLSDEIQSVGSEKNQRVTVDPGPFAQTGYAPVNRGPGEVNDSTVVQPVLDGPYQPAPFDLPVGNRMLLAPTGPGVVVEGTDNSGRWLSVILIEPGVTSETRTYTMFGSSKQVLVSNVSDTKWKLFEMMKTAVDGDYAEWGTLLSDIKIYGMMKYGERLFIYEGETPNARTKGYIVTNYTSVEVRPYSDFYIISRSQESACTEYINNGLPPIQNTRNVVPLAISSRSIKPRKVQPNEDIVVSKTSLWKELQYNRDIIIRFRFDNSIIKAGGLGYKWAEISFKAANYQYNYISDGEEVTAHTTCSVNGVNDFSFNGGSLPTDFAISRYEVIKENSYVYVHYWDDSQAFRNMVYVRSLAANLNDVMCSGGDYSFALLVGQWPVMKGGAVTLHTAGVTLSTQFTDFVSLNSLRFRFRLSVEEPSFTITRTRVSKLYGLPAANPNGGREYYEVAGRFSLISLVPSNDDYQTPIMNSVTVRQDLERRLNELREEFNNLSQEIAVSQLIDLAILPLDMFSMFSGIEGTVNAAKSMATNVIRKFKSSKLASSVSMLTDSLSDAASSISRSTSIRSIGSTASAWTNISKQTQDAVNEVATISSQLSQISGKLRLKEITTQTEGMSFDDISAAVLKANIDRSIQVDKNALPDVITEASEKFIRNRAYRVIDGDEAFEASTDGRFFAYKVETLEEMPFDIEKFADLVTRSPVISAIIDFKTLKNLNDNYGITREQAFNLLRSNPKVLRGFMDQNNPIIKNRIEQLIMQCRL	This protein is part of the following components: host cell cytoplasm, host cell endoplasmic reticulum, host cell plasma membrane, host cell endoplasmic reticulum-Golgi intermediate compartment, viral capsid, viral outer capsid, host cytoskeleton, host cell membrane, membrane, virion component, and host cell rough endoplasmic reticulum. This protein is involved in the following processs: viral entry via permeabilization of inner membrane, viral entry into host cell, permeabilization of host organelle membrane involved in viral entry into host cell, viral life cycle, viral process, and virion attachment to host cell. This protein is located in the following components: viral outer capsid, host cell endoplasmic reticulum-Golgi intermediate compartment, host cell membrane, host cell endoplasmic reticulum, host cytoskeleton, viral capsid, membrane, host cell cytoplasm, host cell plasma membrane, and host cell rough endoplasmic reticulum. This protein is part of membrane: membrane.
MPEGPSVRKFHHLVSPFVGQQVVKTGGSSKKLNPTSFQSLWLQDSQVHGKKLFLRFDPDEEAVSLGNSLLSEPLREGEQKDKARHHQEASDPSSWSPGGDSAVPSGDDGLQCLGGDTPAGGAERWLQVSFGLFGSIRVNEFSRAKKANKRGDWRDPVPRLVLHFSGSGFLAFYNCQMTWRFSSPVVSPASDILSEKFHRGQALEALGREQPICYTLLDQRYFSGLGNIIKNEALFRAGIHPLSPGSLLGLPRLEALVDHVVAFSADWLQGKFQGTRQHTQIYQKEQCPAGHQVVRESLGPPGGFQRLTWWCPQCQPRLSADEPKQLQPS	This protein is part of the following components: spindle microtubule, microtubule cytoskeleton, nucleus, intracellular membrane-bounded organelle, cytoplasm, and nucleoplasm. This protein is involved in the following processs: base-excision repair, cellular response to DNA damage stimulus, metabolic process, DNA repair, and nucleotide-excision repair. This protein is located in the following components: nucleus, nucleoplasm, mitotic spindle, intracellular membrane-bounded organelle, microtubule cytoskeleton, and cytoplasm. This protein enables hydrolase activity: hydrolase activity, acting on glycosyl bonds, hydrolase activity, DNA N-glycosylase activity, and hydrolase activity, hydrolyzing N-glycosyl compounds. This protein is involved in metabolic process: metabolic process. This protein enables metal ion binding: metal ion binding, and zinc ion binding. This protein enables catalytic activity: DNA-(apurinic or apyrimidinic site) endonuclease activity, lyase activity, class I DNA-(apurinic or apyrimidinic site) endonuclease activity, and catalytic activity. This protein is involved in cellular response to DNA damage stimulus: cellular response to DNA damage stimulus, base-excision repair, nucleotide-excision repair, and DNA repair. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: DNA binding, and damaged DNA binding. This protein is part of nucleus: nucleus. This protein enables the following functions: lyase activity, nucleic acid binding, metal ion binding, hydrolase activity, hydrolase activity, hydrolyzing N-glycosyl compounds, damaged DNA binding, microtubule binding, class I DNA-(apurinic or apyrimidinic site) endonuclease activity, zinc ion binding, DNA N-glycosylase activity, DNA binding, catalytic activity, DNA-(apurinic or apyrimidinic site) endonuclease activity, and hydrolase activity, acting on glycosyl bonds.
MESESSRRMGNACIPLKRIAYFLCLFSVVLLTEGKKPAKPKCPAVCTCSKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNAFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSPKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIDTQLYVIVAQLFGGSHIYKRDGFANKFIKIQDIEVLKIRKPNDIETFKIEDNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIARPPLALRTPHLILSSSSQRPVIYQWSKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA	This protein is part of the following components: cell junction, extracellular space, extracellular region, synapse, and glutamatergic synapse. This protein is involved in the following processs: positive regulation of synaptic transmission, positive regulation of cell growth, neuron projection development, axon guidance, and neurotransmitter receptor localization to postsynaptic specialization membrane. This protein acts upstream of or within the following processs: positive regulation of cell growth, neuron projection development, positive regulation of synaptic transmission, and axon guidance. This protein is active in the following component: extracellular space. This protein is located in the following components: extracellular space, synapse, extracellular region, glutamatergic synapse, synaptic cleft, and cell junction. This protein is part of extracellular region: synaptic cleft, and extracellular region. This protein enables the following functions: protein binding, and signaling receptor binding.
MNIIQGNLVGTGLKIGIVVGRFNDFITSKLLSGAEDALLRHGVDTNDIDVAWVPGAFEIPFAAKKMAETKKYDAIITLGTVIRGATTHYDYVCNEAAKGIAQAANTTGVPVIFGIVTTENIEQAIERAGTKAGNKGVDCAVSAIEMANLNRSFE	This protein is part of the following components: cytosol, and riboflavin synthase complex. This protein is involved in the following process: riboflavin biosynthetic process. This protein is active in the following component: cytosol. This protein is involved in metabolic process: riboflavin biosynthetic process. This protein enables transferase activity: 6,7-dimethyl-8-ribityllumazine synthase activity, and transferase activity. This protein is part of cytosol: cytosol. This protein enables the following functions: transferase activity, and 6,7-dimethyl-8-ribityllumazine synthase activity.
MEPIHNPPPQTCSYSRSSTTYTSFKDASCDTKVIRIIIALFLIVISCGLILCAYTFRDLLDADYLAQEGPQQATKLLQQLDDVLTGPPLPIWDNEHLFQFSCLMQNKHKRVLPIDICNPLTKFNFLECICNCLMTKQSVNVNETDMCELFCPPTCTPENYRRLLCTSSVFPFVMWHDPSADTQEAMLTKMDQTMSSGRVGNSHWVLVIVDIEYRCVTFFDSLCDYVASPQQMREQLEGLAVSLGAIYPKEGGADSDQEELLSPFQVRIGSTVKVQSPGEFTCGAWCCQFLAWYLENPDFDLEEKVPKNPSERRALLADFISTTEQAMSRYSSLSWPTTD	This protein is part of the following components: extracellular region, membrane, host cell, and integral component of membrane. This protein is involved in the following processs: proteolysis, protein deubiquitination, and protein deneddylation. This protein is located in the following components: integral component of membrane, extracellular region, membrane, and host cell. This protein enables hydrolase activity: NEDD8-specific protease activity, hydrolase activity, peptidase activity, cysteine-type peptidase activity, and thiol-dependent deubiquitinase. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of extracellular region: extracellular region. This protein is involved in proteolysis: protein deneddylation, protein deubiquitination, and proteolysis. This protein enables the following functions: thiol-dependent deubiquitinase, peptidase activity, cysteine-type peptidase activity, hydrolase activity, and NEDD8-specific protease activity.
MKTTIKDIKTRLFKIPLKEILSDAKHGDHDHFELITTTVTLEDGSQGTGYTYTGGKGGYSIKAMLEYDIQPALIGKDATQIEEIYDFMEWHIHYVGRGGISTFAMSAVDIALWDLKGKREGLPLWKMAGGKNNTCKAYCGGIDLQFPLEKLLNNICGYLESGFNAVKIKIGRENMQEDIDRIKAVRELIGPDITFMIDANYSLTVEQAIKLSKAVEQYDITWFEEPTLPDDYKGFAEIADNTAIPLAMGENLHTIHEFGYAMDQAKLGYCQPDASNCGGITGWLKAADLITEHNIPVCTHGMQELHVSLVSAFDTGWLEVHSFPIDEYTKRPLVVENFRAVASNEPGIGVEFDWDKIAQYEV	This protein is involved in the following processs: carbohydrate metabolic process, and galactose catabolic process. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: isomerase activity. This protein is involved in carbohydrate metabolic process: carbohydrate metabolic process, and galactose catabolic process. This protein enables the following functions: metal ion binding, and isomerase activity.
MICFILFVFSFLVSVSATAPYKPDDVFLINCGETDVPFDNHGRTWTQEEKNILPKNSDNASFSSVVSYKEESGIPQVPYMTARIFRSDFTYSFPVSPGWKFLRLYFYPTSYKSGFDAVNSFVSVTVNDFTLLQNFSADLTVKASIPESKSLIKEFIVPVYLTLNLTFRPSNNSLAFVNGIEIVSMPDRFYSKGGFDDLITNVGSLIDFEIDNSTASETVHRLNVGGHMVDEVNDSGMFRRWLSDDYEFLIGGVSPYMPDVNISYTEKTPAYVAPAYVYSTCRMMGNAQDTYLNLNFNLTWLFTVDAGFSYLVRLHFFEKYLNKANQRVFSIFLGNQMAREEMDVIRLSGGPRIPIYLDFRIYVGSESGPRPDLRLDLHPLVKDNPEYYEAILNGVEILKLNNSGNLAIIQDNELKPNPPLSSNLTPNHVTQQIKGKSSHLLVKIFIAVGPGTGLATFVVVLMLWMRQMKRKNRKEERVVMFKKLLNMYTYAELKKITKSFSYIIGKGGFGTVYGGNLSNGRKVAVKVLKDLKGSAEDFINEVASMSQTSHVNIVSLLGFCFEGSKRAIVYEFLENGSLDQFMSRNKSLTQDVTTLYGIALGIARGLEYLHYGCKTRIVHFDIKPQNILLDGNLCPKVSDFGLAKLCEKRESVLSLMDTRGTIGYIAPEVFSRMYGRVSHKSDVYSFGMLVIDMIGARSKEIVETVDSAASSTYFPDWIYKDLEDGEQTWIFGDEITKEEKEIAKKMIVVGLWCIQPCPSDRPSMNRVVEMMEGSLDALEIPPKPSMHISTEVITESSSLSDGGEDV	This protein is part of the following components: membrane, and integral component of membrane. This protein is involved in the following processs: phosphorylation, response to metal ion, and protein phosphorylation. This protein is located in the following components: membrane, and integral component of membrane. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of membrane: membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables transferase activity: kinase activity, protein serine/threonine kinase activity, protein kinase activity, and transferase activity. This protein is involved in phosphorylation: phosphorylation, and protein phosphorylation. This protein enables the following functions: transferase activity, protein serine/threonine kinase activity, protein kinase activity, ATP binding, kinase activity, and nucleotide binding.
MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELEREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGLRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPAVRDWTLEDSSQELWK	This protein is part of the following component: nucleus. This protein is involved in the following processs: negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, skeletal muscle tissue development, regulation of transcription by RNA polymerase II, and multicellular organism development. This protein is active in the following component: nucleus. This protein is located in the following component: nucleus. This protein enables metal ion binding: metal ion binding. This protein is involved in cellular response to DNA damage stimulus: cellular response to DNA damage stimulus. This protein enables DNA binding: DNA binding, and sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: negative regulation of transcription, DNA-templated, and negative regulation of transcription by RNA polymerase II. This protein enables the following functions: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA binding, nucleic acid binding, sequence-specific DNA binding, and metal ion binding.
MLLYKDVISGDELVSDAYDLKEVDDIVYEADCQMVTVKQGGDVDIGANPSAEDAEENAEEGTETVNNLVYSFRLSPTSFDKKSYMSYIKGYMKAIKARLQESNPERVPVFEKNAIGFVKKILANFKDYDFYIGESMDPDAMVVLMNYREDGITPYMIFFKDGLVSEKF	This protein is part of the following components: cytoplasm, cytosol, and nucleus. This protein is involved in the following processs: regulation of catalytic activity, and cytoplasmic translation. This protein is active in the following component: cytoplasm. This protein is located in the following components: cytoplasm, cytosol, and nucleus. This protein enables metal ion binding: calcium ion binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in translation: cytoplasmic translation. This protein enables the following functions: guanyl nucleotide exchange factor inhibitor activity, protein binding, and calcium ion binding.
MSRSPSPDSPPAVRDDEEKDAREQSDSPTSNTDDPKSPSESPKSNRSQESSRKDSRESGKRRDSHEDEKMPLTPPNRSSEASPQHRRHRESRSPSRSRSRSHRSHSRSQYRRSRSRSRDRRSRSRSRDRRSHSRSRDRRSPARRRSPVRAKSPAQAVKPTEEPEKKKNDPKDLLRTRTGGAYIPPAKLRLMQQQITDKSSEQYQRMNWERMKKKIHGLVNRVNAKNLVQIVRELLQENVIRSKGLLCRDIIQAQAFSPGFSNVYAALAAVINSKFPHIGELLLRRLIVQFKRSFRRNDRGVTVNVIKFIAHLINQQVAHEVLALEIMILMLEEPTDDSVEVAIAFLKECGAKLMEIAPAALNSVYDRLRAILMETERSENALDRRIQYMIETAMQIRKDKFAAYPAVVEDLDLIEEEDQIIHTLNLEDAVDPENGLNVFKLDPEFEKNENVYEEIRKEIIGDADISSDEEEEVEDDDEESEAEEAPRKTTEIIDNTDQNLTAFRREVYLTLQSSLDYQEAAHKLLKMKIPDNLQVNVILKFIQKKSEFQNELCAMLVDCCAQQRTYERFYGMLIERFCRLRLEYQQCFEKLCQDTYATVHRIDITKLRNLARLVAHLLSTDAIEWKILADVKMTEEDTTSAGRIYIKFIFMELVEAMGMVKLHTRVTDPTLAHCFVGMFPRTDPQDARFAINFFTMIGLGGLTLELREWLNRGLKKKKGIIDELKAAQSSSDSSSDSSDSSDSSDSSGSSDSSDDSSSSSSSDSSKEPPKKKKKSGTVLKKKETDTNDHKEARGDSRAERRNDEEKLKRRSDEGRRDRSAENREPRRGRDRRDSGDDRHDRGRRDRSKEKEDRGDKRSQRHDSREEDRRERKDRDRRDRSEERDNRRDRKERSRSRDRRDHRDRSRSRERNEKRRHDDDRRREEKVGSDDRRRRH	This protein is part of the following components: nucleus, nuclear speck, and catalytic step 2 spliceosome. This protein is involved in the following processs: mRNA splicing, via spliceosome, RNA splicing, and mRNA processing. This protein is located in the following components: nucleus, and nuclear speck. This protein is involved in metabolic process: mRNA splicing, via spliceosome, mRNA processing, and RNA splicing. This protein enables RNA binding: RNA binding. This protein is part of nucleus: nucleus. This protein enables the following function: RNA binding.
MEMEEAQEMSQMPGRDSPPPNDVSEENDEAMPIPEDLSASSNLQHNNRGDKEGLACNIKVEARCDEENGLAIDMMMNGEEEEECAEDLRVLDASGAKVNGSHAGGPDSKGPYSSAGGIRLPNGKLKCDICGIVCIGPNVLMVHKRSHTGERPFQCTQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALSGHLRTHSVGKPHKCAYCGRSYKQRSSLEEHKERCHNYLQCMGLQNSIYTVVKEESNQNEQREDLSQMGSKRALVLDRLANNVAKRKSTMPQKFVGEKRFSNISFEGGPGELMQPHVIDQAINSAINYLGAESLRPLIQTSPTSSDMGVMGSMYPLHKPPAEGHGLSAKDSAAENLLLLAKSKSASSEKDGSPSHSGQDSTDTESNNEEKAGVGASGLIYLTNHITSGVRNGVLPLVKEEQQRQYEAMRASIEIASEGFKVLSGEGEQVRAYRCEHCRILFLDHVMYTIHMGCHGFRDPFECNLCGHRSQDRYEFSSHMTRGEHRY	This protein is part of the following component: nucleus. This protein is involved in the following processs: negative regulation of transcription, DNA-templated, and multicellular organism development. This protein is located in the following component: nucleus. This protein enables metal ion binding: metal ion binding. This protein enables DNA binding: DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: negative regulation of transcription, DNA-templated. This protein enables the following functions: DNA binding, metal ion binding, and nucleic acid binding.
MSASRFIKCVTVGDGAVGKTCMLISYTSNTFPTDYVPTVFDNFSANVVVDGSTVNLGLWDTAGQEDYNRLRPLSYRGADVFLLAFSLISKASYENVSKKWIPELRHYAPGVPIILVGTKLDLRDDKQFFVDHPGAVPISTAQGEELRKLIGAAAYIECSSKTQQNIKAVFDAAIKVVLQPPKQKKKKKKAQKGCAIL	This protein is part of the following components: plasma membrane, intracellular membrane-bounded organelle, cell projection, membrane, cytoplasm, nucleus, cytoplasmic vesicle, nucleolus, spindle, site of polarized growth, cell cortex, vesicle, and cytoskeleton. This protein is involved in the following processs: root hair elongation, actin cytoskeleton organization, small GTPase mediated signal transduction, positive gravitropism, regulation of auxin mediated signaling pathway, establishment or maintenance of cell polarity, actin filament organization, root hair initiation, cortical cytoskeleton organization, regulation of cell shape, and regulation of actin cytoskeleton organization. This protein is active in the following components: intracellular membrane-bounded organelle, cell cortex, cell projection, plasma membrane, cytoskeleton, cytoplasmic vesicle, and nucleus. This protein is located in the following components: membrane, and cytoplasm. This protein enables hydrolase activity: GTPase activity. This protein is involved in signal transduction: small GTPase mediated signal transduction. This protein enables nucleotide binding: GTP binding, GDP binding, and nucleotide binding. This protein is part of membrane: plasma membrane, and membrane. This protein is part of cytoplasm: cell cortex, and cytoplasm. This protein is part of nucleus: nucleus. This protein enables the following functions: nucleotide binding, protein kinase binding, GDP binding, GTPase activity, and GTP binding.
MAAQSDKDVKYYTLEEIKKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELSKTFIIGELHPDDRSKLSKPMETLITTVDSNSSWWTNWVIPAISALIVALMYRLYMADD	This protein is part of the following components: endoplasmic reticulum membrane, endoplasmic reticulum, integral component of membrane, membrane, intracellular membrane-bounded organelle, organelle membrane, and cytosol. This protein is located in the following components: endoplasmic reticulum, cytosol, integral component of membrane, membrane, intracellular membrane-bounded organelle, and endoplasmic reticulum membrane. This protein enables metal ion binding: metal ion binding. This protein is part of membrane: endoplasmic reticulum membrane, organelle membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of cytosol: cytosol. This protein enables the following functions: metal ion binding, heme binding, and enzyme binding.
MEAEELIGSSVTIDSIMSKMRDIKNKINEDCTDELSLSKICADHTETVNQIMRVGNTPENWLNFLLKLEKNSSPLNDDLLNKLIGRYSQAIEVLPPDKYGQNESFARIQVRLAELKAIQEPDDARDYFQMARENCKKFAFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPLQMLETAMRNLHLQKKQLLPEEDKKSVSASTVLSAQEPFSSSLGNVQNRSISCESRGQAGAARVLYGENLPPQDAEVRHQNPFKQTHAAKRSCPFGRVPVNLLNSPDFYVKTDSSAVTQLTTRLALSSVPLPYVTCLLHLQLLALAGLAKGSGPDRDAILPGSRPRGSDSYELRGLKPIQTIYLKDSLVSNEKSSELMSDLIALKSKTDSSLTKLEETKPEIAERRPMQWQSTRKPECVFQNPAAFAPLRHVPDVTPKADKESPPISVPKWLDPKSACETPSSSSLDDYMKCFKTPVVKNDFPPACPSSTPYSQLARLQQQQQQGLSTPLQSLQISGSSSINECISVNGRIYSILKQIGSGGSSKVFQVLNEKKQINAIKYVNLEDADSQTIESYRNEIAFLNKLQQHSDKIIRLYDYEITEQYIYMVMECGNIDLNSWLKKKKSINPWERKSYWKNMLEAVHIIHQHGIVHSDLKPANFVIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSSRENSKIRTKVSPRSDVWSLGCILYYMTYGRTPFQHIINQVSKLHAIINPAHEIEFPEISEKDLRDVLKCCLVRNPKERISIPELLTHPYVQIQPHPGSQMARGATDEMKYVLGQLVGLNSPNSILKTAKTLYERYNCGEGQDSSSSKTFDKKRERK	This protein is part of the following components: spindle, cytoplasm, nucleus, and kinetochore. This protein is involved in the following processs: protein phosphorylation, peptidyl-serine phosphorylation, mitotic spindle assembly checkpoint signaling, protein localization to kinetochore, chromosome segregation, meiotic spindle assembly checkpoint signaling, chromosome separation, mitotic cell cycle checkpoint signaling, and phosphorylation. This protein acts upstream of or within the following processs: protein localization to meiotic spindle midzone, protein localization to kinetochore, protein localization to chromosome, peptidyl-threonine phosphorylation, peptidyl-tyrosine phosphorylation, female meiosis chromosome segregation, meiotic spindle assembly checkpoint signaling, protein autophosphorylation, and peptidyl-serine phosphorylation. This protein is active in the following components: spindle, nucleus, and kinetochore. This protein is located in the following components: kinetochore, and cytoplasm. This protein is involved in signal transduction: mitotic spindle assembly checkpoint signaling, mitotic cell cycle checkpoint signaling, and meiotic spindle assembly checkpoint signaling. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables transferase activity: transferase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein kinase activity, kinase activity, and protein tyrosine kinase activity. This protein is involved in phosphorylation: peptidyl-serine phosphorylation, protein autophosphorylation, peptidyl-threonine phosphorylation, protein phosphorylation, peptidyl-tyrosine phosphorylation, and phosphorylation. This protein enables the following functions: kinase activity, transmembrane receptor protein tyrosine kinase activity, kinetochore binding, protein threonine kinase activity, transferase activity, protein serine/threonine kinase activity, nucleotide binding, protein serine/threonine/tyrosine kinase activity, ATP binding, protein serine kinase activity, protein tyrosine kinase activity, and protein kinase activity.
MKNPMLEAASLLLEKLLLISNFKLFSVSVPGGGTGKNRPYEISSFVRGDVLEVSRTHFIHYGIYLGENRVAHLMPDILLALTNDKERTQKVVSNKRLLLGVICKVASIRVDTVEDFAYGADILVNHLDGTLKKKSLLNEEVARRAEQQLGLTPYSLLWNNCEHFVTYCRYGSRISPQAEKFYDTVKIIIRDQRSSLASAVLGLASIVYTGLASYMTLPAICIPFCLWMMSG	This protein is part of the following components: endosome, integral component of membrane, intracellular membrane-bounded organelle, endoplasmic reticulum, perinuclear region of cytoplasm, cytoplasm, multivesicular body, membrane, rough endoplasmic reticulum, and endoplasmic reticulum membrane. This protein is involved in the following processs: response to vitamin A, vitamin A metabolic process, visual perception, response to retinoic acid, retinol metabolic process, and response to stimulus. This protein acts upstream of or within the following processs: response to bacterium, vitamin A metabolic process, positive regulation of lipid transport, 1,2-diacyl-sn-glycero-3-phosphocholine metabolic process, cellular response to leukemia inhibitory factor, and retinol metabolic process. This protein is located in the following components: cytoplasm, endosome, membrane, multivesicular body, endoplasmic reticulum, endoplasmic reticulum membrane, intracellular membrane-bounded organelle, rough endoplasmic reticulum, integral component of membrane, and perinuclear region of cytoplasm. This protein is involved in metabolic process: 1,2-diacyl-sn-glycero-3-phosphocholine metabolic process. This protein is part of membrane: membrane, and endoplasmic reticulum membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of cytoplasm: cytoplasm. This protein enables transferase activity: lecithin, O-acyltransferase activity, phosphatidylcholine-retinol O-acyltransferase activity, transferase activity, and acyltransferase activity. This protein is involved in lipid metabolic process: vitamin A metabolic process, and retinol metabolic process. This protein enables the following functions: lecithin, retinoic acid binding, O-acyltransferase activity, transferase activity, retinol binding, acyltransferase activity, and phosphatidylcholine-retinol O-acyltransferase activity.
MRIMASPFAVLLQNVSFRYTADARFILHEVDLAIPKGAYLSVVGENGSGKSTLVKLVLKLLKPSTGTIAHFVQRVGSVPQTKMHTLYFPLTVYEMLNSYRRLLRISHKWVVDAVLEEVGMRGAKKKLVYTLSGGELQKVYIARSLIGDPDLLVLDELSTGIDSRGQKDIYALLKGLNTSRNVTVISVEHNLDAAITNSTQIFHLSEGHGHLCNPQQYVSEFLDMQKKDALACAQCRSR	This protein is part of the following components: membrane, and plasma membrane. This protein is located in the following components: plasma membrane, and membrane. This protein enables hydrolase activity: ATP hydrolysis activity. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein is part of membrane: plasma membrane, and membrane. This protein enables the following functions: ATP binding, nucleotide binding, and ATP hydrolysis activity.
MNTNLLFIPLKQSSVLDLGDELRQVITNNYFQPASSFNSDLIYITQLRNQVAQIKNVNDELGKTSQDDSILLEYLQVLNTLQNKFSDDCVEFAWFDTLAYGPQGPYRYRSLKIEKLNVIYQIGSLYSQIAISESRHTDIGLKRACHYFQLSAGCFMFINNFLIETIKNKNDPLVLSIPLSMQSSTIQCLEYLMLAQAQETIWQKAINNNSMKDSVVARLSIQTSEYYSKALDFGNSSDLIKLEWINHMKVKKLHFLAAAHLRSSTIAADSFQYGEQVAHLRVASQAVDQALKSKKYVNSLVLEDLQGLADVIKVRLRTAEKDNDLVYLKIVPQEKELKTIIGVSMVKSIIPEAFEQKPESNTEIFKELLPYVIIHVAQAMRERQDEYVQTKFHTPISSLNNMLVKFLIDRDLPSSIDSIQQPENIPDSVIHHSQEILKTGGVDFIDKAFKELDKLKLECNHLLQECETRIDLDRSEDDMLRRKQGSTRWTRKSTDDAAQELIKKVDKMKQYLLQANNGDGFVLKKFYDIKPALDVYSSGYKALSQYIPNSQYIELPEQLSIVISDLRSCLARANTLESERKEFLQTLEIRSRDNSILPKLITEYNSNRSKYQTENGEFNFNAFESVYEKHMKLFDSDIKYIARTRDSQMTLEHEIDSINQKFVQEFKSLQNSSNEKRQQVLQYLETAYEKFLEIINNLTEGSKFYTDFIEKGSAVLQECEEYLYRRRVESRDLELAISNSFQQQQQVQEQNEQLSVPRNYSNDKLISPKTSKPGLWNPNSDIQFS	This protein is involved in the following processs: cellular response to lithium ion, filamentous growth of a population of unicellular organisms in response to pH, cellular response to neutral pH, entry into host, filamentous growth of a population of unicellular organisms, cellular response to pH, filamentous growth, and positive regulation of filamentous growth of a population of unicellular organisms. This protein enables the following function: molecular_function.
MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLDLLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSETQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGSSVVMGCKAAGATRIIGVDVNKEKFKKARELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGLLPASVQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAKKLNLDPLITHTLNLDKINEAVELMKTGKCIRCILLL	This protein is part of the following component: cytoplasm. This protein is located in the following component: cytoplasm. This protein enables metal ion binding: zinc ion binding, and metal ion binding. This protein enables catalytic activity: oxidoreductase activity, and alcohol dehydrogenase (NAD+) activity. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: metal ion binding, alcohol dehydrogenase [NAD(P)+] activity, oxidoreductase activity, alcohol dehydrogenase (NAD+) activity, and zinc ion binding.
MLKYALHSGGMPRNRLLRQLSAYIFRRSYSSNIRNIGILAHIDAGKTTTTERMLFYSGKTRSLGEVHRGNTVTDYLTQERERGITICSSAVTFPWSGNRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWTQADKHKLPRLAFVNKMDRPDADFDKCVNDLRTKLETQPVCIQYPSKNQDGLLAINDVITLEQLTWQPKDLGRSYSKTKLEPSDDLRQLQEKRNELIDQLSGLDDELADVVISTESFDNVSNALIERALRRATCQQKVVPVLLGSAYKNVGIQRLMDAVNTYLPAPEERNQIYDCFGNEVAGKVFKIVHDKQRGPLTLVRILRGEIKRGMRLICSRGQAEVVSKLYEPLADEYREVGAVQSGDVVICAGLKSTVTGDLLTSSQTALRNAQKRLKQSQGTVSADEDEELDTDELFGIDRQIPDAVYFCSIEPPSVSSQTAMEQALRQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIESPSLTTLSVEKEIAGSKQNVSLTLEVVKDHDELFSLDKSPENLSNLNTLRPRTLQVIRKGSVSALERGPRVGGQVVDTQIRLHNAIIGRGTADSFVMATAAQCVQKLLSTSGTRLLEPIMALQIVAPSERISGIMADLSRRRALINDVLPKGERNKMILVNAPLAELSGYSSALRTISSGTASMTMQPSGFSGMNAVDESLAERRVQGLE	This protein is part of the following component: mitochondrion. This protein is involved in the following processs: translation, mitochondrial translation, and ribosome disassembly. This protein is located in the following component: mitochondrion. This protein enables hydrolase activity: GTPase activity. This protein enables nucleotide binding: nucleotide binding, and GTP binding. This protein is part of mitochondrion: mitochondrion. This protein is involved in translation: mitochondrial translation, and translation. This protein enables the following functions: GTP binding, GTPase activity, and nucleotide binding.
MLTEQQRRELDWEKTDGLMPAIVQHAVSGEVLTLGYMNPQALDKTIESGHVTFFSRTKQRLWTKGETSGHVLNVVSIAPDCDNDTLLVLANPVGPTCHKGTSSCFGDASHQWLFLYQLEQLLAERKTADPASSYTAKLYASGTKRIAQKVGEEGVETALAATVNDRFELTNEASDLMYHLLVLLQDQDLNLTTVIDDLRKRHQ	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: metabolic process, cellular amino acid biosynthetic process, and histidine biosynthetic process. This protein is located in the following component: cytoplasm. This protein enables hydrolase activity: phosphoribosyl-AMP cyclohydrolase activity, hydrolase activity, and phosphoribosyl-ATP diphosphatase activity. This protein is involved in metabolic process: metabolic process. This protein enables catalytic activity: catalytic activity. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein is part of cytoplasm: cytoplasm. This protein is involved in cellular amino acid biosynthetic process: histidine biosynthetic process, and cellular amino acid biosynthetic process. This protein enables the following functions: hydrolase activity, phosphoribosyl-ATP diphosphatase activity, nucleotide binding, ATP binding, catalytic activity, and phosphoribosyl-AMP cyclohydrolase activity.
MAGVAQNGHQEMDFCMKVDPLNWEMAADSLKGSHLDEVKKMVAEFRKPVVKLGGETLTVAQVAAIAAKDNVKTVKVELSEGARAGVKASSDWVMDSMGKGTDSYGVTTGFGATSHRRTKNGGALQKELIRFLNAGVFGNGTESCHTLPQSGTRAAMLVRINTLLQGYSGIRFEILEAITKLLNHNVTPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAVGPNGETLNAEEAFRVAGVNGGFFELQPKEGLALVNGTAVGSGLASMVLFDANVLAVFSEVLSAIFAEVMNGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYVKAAQKLHETDPLQKPKQDRYALRTSPQWLGPQIEVIRSATKMIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNARLALASIGKLMFGQFSELVNDYYNNGLPSNLTAGRNPSLDYGFKGSEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLDLISARKTAEAVDILKLMSSTYLVALCQAIDLRHLEENLRNAVKNTVSQVAKRTLTMGTNGELHPSRFCEKDLLRVVDREYVFAYADDACSANYPLMQKLRQVLVDHALQNGENEKNANSSIFQKILAFEDELKAVLPKEVESARAALESGNPAIANRIKECRSYPLYRFVRGELGAELLTGEKVRSPGEECDKVFTAMCNGQIIDSLLECLKEWNGAPLPIC	This protein is part of the following component: cytoplasm. This protein is involved in the following processs: L-phenylalanine catabolic process, phenylpropanoid metabolic process, and cinnamic acid biosynthetic process. This protein is located in the following component: cytoplasm. This protein is involved in metabolic process: L-phenylalanine catabolic process, phenylpropanoid metabolic process, and cinnamic acid biosynthetic process. This protein enables catalytic activity: phenylalanine ammonia-lyase activity, catalytic activity, ammonia-lyase activity, and lyase activity. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: lyase activity, catalytic activity, phenylalanine ammonia-lyase activity, and ammonia-lyase activity.
MAIHLVIIDALNLIRRVHSAQPDPTDIANTIQNTCRTLQRIISESHPTHIVAVFDHLGSDRGWRAEILPEYKQGRKPMPEPLLNGLEKIQDAWWQLGIDSLLSEGDEADDLVATLACKVAQHGEKVTIISTDKGYCQLLSPTLQIRDYFQHRWLDQPFIEQEFGVKPQQLSDYWGLTGISSSQVTGIPGIGPKAAKEILSQFDDIEQAFLSPDLPKKYRTKFDQHIELARRCKRVSALKTDIELGFNLQDLRFTANETH	This protein is involved in the following processs: nucleic acid phosphodiester bond hydrolysis, and DNA replication, Okazaki fragment processing. This protein enables hydrolase activity: endonuclease activity, 5'-flap endonuclease activity, flap endonuclease activity, nuclease activity, and hydrolase activity. This protein is involved in metabolic process: DNA replication, Okazaki fragment processing, and nucleic acid phosphodiester bond hydrolysis. This protein enables metal ion binding: metal ion binding, magnesium ion binding, and potassium ion binding. This protein enables catalytic activity: catalytic activity. This protein enables DNA binding: DNA binding. This protein enables the following functions: 5'-flap endonuclease activity, endonuclease activity, potassium ion binding, nuclease activity, magnesium ion binding, hydrolase activity, flap endonuclease activity, catalytic activity, metal ion binding, and DNA binding.
MKVASIFLLTALVLMSLSGNSGANILGREAKCTNEVNGCPRIYNPVCGTDGVTYSNECLLCMENKERQTPVLIQKSGPC	This protein is part of the following components: extracellular region, and extracellular space. This protein is involved in the following processs: regulation of acrosome reaction, negative regulation of calcium ion import, negative regulation of nitric oxide mediated signal transduction, regulation of store-operated calcium entry, sperm capacitation, negative regulation of serine-type endopeptidase activity, negative regulation of peptidase activity, and negative regulation of peptidyl-tyrosine phosphorylation. This protein is located in the following components: extracellular space, and extracellular region. This protein is part of extracellular region: extracellular region. This protein enables the following functions: peptidase inhibitor activity, and serine-type endopeptidase inhibitor activity.
MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKVTMLKLDPYINVDPGTMSPFQHGEVFVTHDGAETDLDLGHYERFIRTTMTQNNNFTTGRIYEHVLRKERRGDYLGATIQVIPHITDEIKRRIIKGAGDADVALVEIGGTVGDIESQPFLEAIRQLRVEVGSKRAMLMHLTLVPYIATAGETKTKPTQHSVKELRSIGLQPDVLICRSDHPVDASSRRKIALFTNVEERAVISLEDVDTIYKIPGVLHAQGLDDFVVERFGLQCNGADLSEWDKVVDAKLNPEHEVTIAMVGKYMELLDAYKSLIEAMSHAGITNRTKVNLRYIDSEDIENQGTSLLEGADAILVPGGFGLRGVEGKITAVQYARENKVPYLGICLGMQVAVIEFARNVMGWKDANSTEFDRNSGHPVVGLITEWADATGAVETRDEASDLGGTMRLGAQDCQLAAGSKVHDCYGKDVITERHRHRYEVNNNLLPQLVEAGLVVSGRSEDGALVEVVESKDHPWFVACQFHPEFTSTPRDGHPLFSGFVKAALAQKNKA	This protein is involved in the following processs: CTP biosynthetic process, pyrimidine nucleotide biosynthetic process, 'de novo' CTP biosynthetic process, and glutamine metabolic process. This protein is involved in metabolic process: glutamine metabolic process, pyrimidine nucleotide biosynthetic process, 'de novo' CTP biosynthetic process, and CTP biosynthetic process. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: ligase activity, and CTP synthase activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein enables the following functions: ligase activity, nucleotide binding, CTP synthase activity, ATP binding, and metal ion binding.
MGKAFSQLTSQKDEDKSILPDNPAMASKAANYFSTGNRKPSHSCVPCEKAASTSFVTCPTCQGNGEIPQELEKQLVALIPYGDQRLKPRRTKLSVFLAVTICLLIFSLTIFFLYPRNIVVHPVGLNSSTVAFDETHVQLNMTNVLNITNSNFYPVTVTQLTAEVLHQTSVVGQVTSSLRLHIGPLASKQMPYEVASRILDENTYKICTWPKIRVHHILVNIQGALTCSYLTHPQQLPFESFEYVDCRENMSMPHLELPRPA	This protein is part of the following components: integral component of membrane, cellular_component, plasma membrane, and membrane. This protein is involved in the following processs: positive regulation of tumor necrosis factor production, interleukin-6 production, interleukin-6 production, macrophage activation, positive regulation of MAPK cascade, immune system process, CD86 biosynthetic process, positive regulation of I-kappaB kinase/NF-kappaB signaling, tumor necrosis factor production, positive regulation of interleukin-6 production, biological_process, positive regulation of MHC class II biosynthetic process, positive regulation of nitric oxide metabolic process, interleukin-1 beta production, innate immune response, CD80 biosynthetic process, interleukin-1 beta production, and positive regulation of interleukin-1 beta production. This protein is active in the following component: cellular_component. This protein is located in the following components: membrane, integral component of membrane, and plasma membrane. This protein is involved in metabolic process: CD86 biosynthetic process, and CD80 biosynthetic process. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables the following function: molecular_function.
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE	This protein is part of the following components: perinuclear region of cytoplasm, recycling endosome, nucleoplasm, early endosome, terminal web, cytoplasmic vesicle, extracellular space, HFE-transferrin receptor complex, plasma membrane, basal part of cell, integral component of plasma membrane, membrane, integral component of membrane, apical part of cell, and external side of plasma membrane. This protein is involved in the following processs: regulation of protein localization to cell surface, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, BMP signaling pathway, positive regulation of gene expression, response to iron ion starvation, negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I, cellular response to iron ion, multicellular organismal iron ion homeostasis, positive regulation of receptor-mediated endocytosis, liver regeneration, hormone biosynthetic process, ion transport, iron ion homeostasis, response to iron ion, positive regulation of ferrous iron binding, negative regulation of T cell antigen processing and presentation, negative regulation of T cell cytokine production, negative regulation of signaling receptor activity, iron ion import across plasma membrane, positive regulation of pathway-restricted SMAD protein phosphorylation, female pregnancy, negative regulation of ubiquitin-dependent protein catabolic process, negative regulation of CD8-positive, alpha-beta T cell activation, negative regulation of receptor binding, positive regulation of receptor binding, antigen processing and presentation of endogenous peptide antigen via MHC class Ib, acute-phase response, positive regulation of T cell mediated cytotoxicity, positive regulation of transferrin receptor binding, positive regulation of peptide hormone secretion, positive regulation of signaling receptor activity, cellular response to iron ion starvation, regulation of iron ion transport, protein-containing complex assembly, cellular iron ion homeostasis, transferrin transport, and positive regulation of protein binding. This protein does not enable the following function: peptide antigen binding. This protein is not involved in the following processs: antigen processing and presentation, and antigen processing and presentation of peptide antigen via MHC class I. This protein is not part of the following component: MHC class I protein complex. This protein is active in the following components: external side of plasma membrane, and extracellular space. This protein is located in the following components: integral component of membrane, terminal web, early endosome, cytoplasmic vesicle, integral component of plasma membrane, apical part of cell, basal part of cell, membrane, plasma membrane, extracellular space, nucleoplasm, recycling endosome, perinuclear region of cytoplasm, and external side of plasma membrane. This protein is involved in signal transduction: BMP signaling pathway. This protein is involved in metabolic process: hormone biosynthetic process. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane, and integral component of plasma membrane. This protein is involved in cation transport: transferrin transport, iron ion import across plasma membrane, and ion transport. This protein enables the following functions: protein binding, transferrin receptor binding, beta-2-microglobulin binding, co-receptor binding, and signaling receptor binding.
MWSYVWLPLVALSLFKDSIIMAKAATILLPSQTGFDISRSPVCSAPDPNLNYRPVIGILSHPGDGASGRLSNATDASSIAASYVKLAESGGARVIPLIFNEPEEILFQKLELVNGVILTGGWAKEGLYFEIVKKIFNKVLERNDAGEHFPIYAICLGFELLTMIISQNRDIFEKMDARNSASSLQFVENVNIQGTIFQRFPPELLKKLGTDCLVMQNHRFGISPQSFEGNIALSNFFKIVTTCVDDNGKVYVSTVQSTKYPVTGFQWHPEKNAFEWGSSKIPHSEDAIQVTQHAANHLVSEARKSLNRPESKKVLSNLIYNYKPTYCGYAGIGYDEVYIFTQQRSLL	This protein is part of the following components: cell wall, extracellular space, vacuole, and extracellular region. This protein is involved in the following processs: proteolysis, and tetrahydrofolylpolyglutamate metabolic process. This protein is active in the following component: vacuole. This protein is located in the following components: vacuole, cell wall, extracellular region, and extracellular space. This protein enables hydrolase activity: hydrolase activity, gamma-glutamyl-peptidase activity, and omega peptidase activity. This protein is involved in metabolic process: tetrahydrofolylpolyglutamate metabolic process. This protein is part of extracellular region: extracellular region. This protein is involved in proteolysis: proteolysis. This protein enables the following functions: gamma-glutamyl-peptidase activity, omega peptidase activity, and hydrolase activity.
MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNKITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAATDHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD	This protein is involved in the following process: cellular modified amino acid biosynthetic process. This protein is involved in metabolic process: cellular modified amino acid biosynthetic process. This protein enables catalytic activity: ligase activity, forming carbon-nitrogen bonds, ligase activity, glutamate-cysteine ligase activity, and catalytic activity. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein enables the following functions: glutamate-cysteine ligase activity, ligase activity, nucleotide binding, ligase activity, forming carbon-nitrogen bonds, catalytic activity, and ATP binding.
MGSLAAEKTVTGWAARDASGHLTPYNYTLRKTGPEDVVVKVLYCGICHTDIHQAKNHLGASKYPMVPGHEVVGEVVEVGPEVTKYSAGDVVGVGVIVGCCRECHPCKANVEQYCNKRIWSYNDVYTDGRPTQGGFASAMVVDQKFVVKIPAGLAPEQAAPLLCAGLTVYSPLKHFGLMSPGLRGGVLGLGGVGHMGVKVAKSMGHHVTVISSSARKRGEAMDDLGADAYLVSSDAAAMAAAGDSLDYIIDTVPVHHPLEPYLALLKLDGKLILMGVINQPLSFISPMVMLGRKAITGSFIGSMAETEEVLNFCVDKGLTSQIEVVKMDYVNQALERLERNDVRYRFVVDVAGSNIDDADAPPA	This protein is involved in the following processs: phenylpropanoid biosynthetic process, and lignin biosynthetic process. This protein is involved in metabolic process: lignin biosynthetic process, and phenylpropanoid biosynthetic process. This protein enables metal ion binding: zinc ion binding, and metal ion binding. This protein enables catalytic activity: oxidoreductase activity, sinapyl alcohol dehydrogenase activity, cinnamyl-alcohol dehydrogenase activity, and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. This protein enables the following functions: metal ion binding, cinnamyl-alcohol dehydrogenase activity, zinc ion binding, oxidoreductase activity, sinapyl alcohol dehydrogenase activity, and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor.
MAALSGGGGSSSGGGGGGGGGGGGGDGGGGAEQGQALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLVFQTPTDASRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPVPQEEASFPETALPSGSSSAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSSSEDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH	This protein is part of the following components: neuron projection, cytoplasm, plasma membrane, cell body, nucleus, cytosol, membrane, intracellular membrane-bounded organelle, and mitochondrion. This protein is involved in the following processs: response to cAMP, trehalose metabolism in response to stress, establishment of protein localization to membrane, intracellular signal transduction, positive regulation of ERK1 and ERK2 cascade, MAPK cascade, positive regulation of peptidyl-serine phosphorylation, protein phosphorylation, cellular response to nerve growth factor stimulus, negative regulation of apoptotic process, signal transduction, negative regulation of neuron apoptotic process, response to peptide hormone, positive regulation of glucose transmembrane transport, positive regulation of gene expression, phosphorylation, metabolic process, epidermal growth factor receptor signaling pathway, and cellular response to calcium ion. This protein acts upstream of or within the following processs: thymus development, cellular response to drug, protein phosphorylation, head morphogenesis, T cell receptor signaling pathway, alpha-beta T cell differentiation, establishment of protein localization to membrane, negative regulation of endothelial cell apoptotic process, trehalose metabolism in response to stress, positive regulation of substrate adhesion-dependent cell spreading, positive T cell selection, CD4-positive or CD8-positive, alpha-beta T cell lineage commitment, negative regulation of neuron apoptotic process, negative regulation of fibroblast migration, positive regulation of gene expression, cell differentiation, regulation of axon regeneration, positive regulation of stress fiber assembly, negative regulation of apoptotic process, thyroid gland development, face development, regulation of T cell differentiation, regulation of cell population proliferation, negative regulation of synaptic vesicle exocytosis, positive regulation of axonogenesis, visual learning, cellular response to calcium ion, response to cAMP, epidermal growth factor receptor signaling pathway, positive regulation of ERK1 and ERK2 cascade, long-term synaptic potentiation, positive regulation of glucose transmembrane transport, positive regulation of axon regeneration, MAPK cascade, response to peptide hormone, positive regulation of peptidyl-serine phosphorylation, CD4-positive, alpha-beta T cell differentiation, myeloid progenitor cell differentiation, and somatic stem cell population maintenance. This protein is active in the following component: plasma membrane. This protein is located in the following components: plasma membrane, nucleus, neuron projection, mitochondrion, cytoplasm, intracellular membrane-bounded organelle, membrane, cytosol, and cell body. This protein is involved in signal transduction: signal transduction, T cell receptor signaling pathway, MAPK cascade, epidermal growth factor receptor signaling pathway, and intracellular signal transduction. This protein is involved in metabolic process: metabolic process. This protein enables metal ion binding: calcium ion binding, and metal ion binding. This protein enables catalytic activity: catalytic activity. This protein enables nucleotide binding: ATP binding, and nucleotide binding. This protein is part of membrane: plasma membrane, and membrane. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables transferase activity: protein kinase activity, MAP kinase kinase kinase activity, transferase activity, kinase activity, and protein serine/threonine kinase activity. This protein is part of cytosol: cytosol. This protein is involved in carbohydrate metabolic process: trehalose metabolism in response to stress. This protein is involved in phosphorylation: phosphorylation, and protein phosphorylation. This protein enables the following functions: small GTPase binding, kinase activity, MAP kinase kinase kinase activity, protein-containing complex binding, protein binding, nucleotide binding, protein threonine kinase activity, transferase activity, protein serine kinase activity, protein kinase activity, metal ion binding, scaffold protein binding, mitogen-activated protein kinase kinase binding, calcium ion binding, ATP binding, identical protein binding, protein serine/threonine kinase activity, small GTPase binding, and catalytic activity.
MVEADHPGKLFIGGLNRETNEKMLKAVFGKHGPISEVLLIKDRTSKSRGFAFITFENPADAKNAAKDMNGKSLHGKAIKVEQAKKPSFQSGGRRRPPASSRNRSPSGSLRSARGSRGGTRGWLPSQEGHLDDGGYTPDLKMSYSRGLIPVKRGPSSRSGGPPPKKSAPSAVARSNSWMGSQGPMSQRRENYGVPPRRATISSWRNDRMSTRHDGYATNDGNHPSCQETRDYAPPSRGYAYRDNGHSNRDEHSSRGYRNHRSSRETRDYAPPSRGHAYRDYGHSRRDESYSRGYRNRRSSRETREYAPPSRGHGYRDYGHSRRHESYSRGYRNHPSSRETRDYAPPHRDYAYRDYGHSSWDEHSSRGYSYHDGYGEALGRDHSEHLSGSSYRDALQRYGTAHGAPPARGPRMSYGGSTCHAYSNTRDRYGRSWESYSSCGDFHYCDREHVCRKDQRNPPSLGRVLPDPREACGSSSYVASIVDGGESRSEKGDSSRY	This protein is part of the following components: ribonucleoprotein complex, nucleus, and U2 snRNP. This protein is involved in the following processs: mRNA processing, and RNA splicing. This protein is active in the following component: nucleus. This protein is located in the following component: nucleus. This protein is involved in metabolic process: mRNA processing, RNA splicing, and mRNA splicing, via spliceosome. This protein enables RNA binding: RNA binding. This protein is part of nucleus: nucleus. This protein enables the following functions: protein binding, RNA binding, and nucleic acid binding.
MTQEPFREELAYDRMPTLERGRQDPASYAPDAKPSDLQLSKRLPPCFSHKTWVFSVLMGSCLLVTSGFSLYLGNVFPAEMDYLRCAAGSCIPSAIVSFTVSRRNANVIPNFQILFVSTFAVTTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAATVIIAARSSEEDCKKKKGSMSDSANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHLSVTFFWILVACFPSAIASHVAAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSIMRIVEMFKDYPPAIKPSYDVLLLLLLLVLLLQAGLNTGTAIQCVRFKVSARLQGASWDTQNGPQERLAGEVARSPLKEFDKEKAWRAVVVQMAQ	This protein is part of the following components: early endosome, apical plasma membrane, caveola, membrane raft, endoplasmic reticulum, plasma membrane, lysosome, cytoplasmic vesicle, recycling endosome, cell-cell junction, integral component of membrane, basolateral plasma membrane, membrane, perinuclear region of cytoplasm, astrocyte end-foot, endosome, and cytoplasm. This protein is involved in the following processs: ion transport, protein transport, caveolin-mediated endocytosis, positive regulation of intracellular transport, cellular response to cholesterol, vesicle-mediated transport, and regulation of response to osmotic stress. This protein is not part of the following component: clathrin-coated vesicle. This protein is active in the following components: plasma membrane, cytoplasmic vesicle, and endoplasmic reticulum. This protein is located in the following components: endoplasmic reticulum, cytoplasmic vesicle, caveola, recycling endosome, cytosol, integral component of membrane, cytoplasm, plasma membrane, lysosome, membrane raft, perinuclear region of cytoplasm, early endosome, membrane, basolateral plasma membrane, and endosome. This protein is not located in the following component: clathrin-coated vesicle. This protein is part of membrane: membrane raft, caveola, membrane, plasma membrane, basolateral plasma membrane, and apical plasma membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of cytoplasm: cytoplasm. This protein is involved in cation transport: ion transport. This protein is involved in protein transport: protein transport. This protein enables the following functions: identical protein binding, protein binding, and protein-containing complex binding.
MSAPKNEMYYSLLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWLSKIKASAVGSNWRLRMSNLKKVTQSVYDYYSDVLNYSLSDFSKPDLQSIAEKCDLGELERLLQLVLGCAVNCAEKQSYITEIMCLEEELQANIMRALQELEATRQASSAEGGVVSSLSRSPRTGILDSKAVQEDRDALAQKCFETEKKMLLLIDEKTNLQQELHKLQQEFARLEQHSTVIGDDGVSLGPVQSGSVRYNELRRQLDLLKEELLQSEGAREDLKLKAQQQDTDLLHMQMRIEELMKSSAEVTTLKDEVDVLRESNDKLKICEAQLDTYKKKLEDYNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQVELFKKEIQDLHAKLDAESSKNVKLEFDNKNLDGKNLALQRAKDSLLKERDNLREAVDELKCGQLSSNTALTGTTVSRELQPSATVEKLQRLEAENKALREGQGGQTALAQLLDDANKRCENLREQLKTANERILSLSHASQSDDPILKESEFGKQIKQLMELNEQKTLQLEEAVTQSTSLQCKVTQLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDPRIASALDASVLEKSADLVEDEPKPKMSVMEEQLMTSAFYRLGVNAQRDAIDSKLAILMGSGQTFLARQRQSAPRKSLSAMKSK	This protein is part of the following components: cell junction, cytoskeleton, synapse, endosome, cytoplasm, and microtubule. This protein is involved in the following processs: cytoplasmic microtubule organization, determination of adult lifespan, multicellular organism development, cytoskeleton-dependent intracellular transport, and endocytosis. This protein is located in the following components: cytoskeleton, endosome, microtubule, cytoplasm, synapse, and cell junction. This protein is part of cytoplasm: cytoplasm. This protein enables the following functions: small GTPase binding, microtubule binding, and small GTPase binding.
MGKIKIGINGFGRIGRLVARVALQSEDVELVAVNDPFITTEYMTYMFKYDTVHGQWKHHEVKVKDSKTLIFGTKEVAVFGCRNPEEIPWAAAGAEYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEKEYKSDVNIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHAITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTVDVSVVDLTVRLEKPASYDQIKAAIKEEAEGKLKGILGYVEEDLVSTDFQGDSRSSIFDAKAGIALSDTFVKLVSWYDNEWGYSTRVIDLIRHMHSTN	This protein is part of the following components: cytoplasm, and cytosol. This protein is involved in the following processs: glycolytic process, and glucose metabolic process. This protein is active in the following component: cytosol. This protein is located in the following component: cytoplasm. This protein enables catalytic activity: oxidoreductase activity, glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, and oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. This protein enables nucleotide binding: NADP binding, and NAD binding. This protein is part of cytoplasm: cytoplasm. This protein is part of cytosol: cytosol. This protein is involved in carbohydrate metabolic process: glucose metabolic process. This protein is involved in phosphorylation: glycolytic process. This protein enables the following functions: NADP binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, oxidoreductase activity, NAD binding, and glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity.
MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDIYNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQKGHSGLHPTGLVS	This protein is part of the following components: MHC class II protein complex, endosome, endoplasmic reticulum, integral component of lumenal side of endoplasmic reticulum membrane, Golgi apparatus, clathrin-coated endocytic vesicle membrane, ER to Golgi transport vesicle membrane, integral component of membrane, Golgi membrane, plasma membrane, lysosomal membrane, endosome membrane, endocytic vesicle membrane, lysosome, extracellular exosome, late endosome membrane, trans-Golgi network membrane, endoplasmic reticulum membrane, transport vesicle membrane, and membrane. This protein is involved in the following processs: interferon-gamma-mediated signaling pathway, immune system process, antigen processing and presentation, adaptive immune response, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, T cell receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class II, and immune response. This protein is located in the following components: endoplasmic reticulum, Golgi membrane, lysosome, clathrin-coated endocytic vesicle membrane, integral component of lumenal side of endoplasmic reticulum membrane, endoplasmic reticulum membrane, membrane, late endosome membrane, endosome membrane, ER to Golgi transport vesicle membrane, extracellular exosome, trans-Golgi network membrane, transport vesicle membrane, lysosomal membrane, plasma membrane, Golgi apparatus, integral component of membrane, endosome, and endocytic vesicle membrane. This protein is involved in signal transduction: T cell receptor signaling pathway, and interferon-gamma-mediated signaling pathway. This protein is part of membrane: trans-Golgi network membrane, endoplasmic reticulum membrane, membrane, late endosome membrane, Golgi membrane, lysosomal membrane, plasma membrane, endocytic vesicle membrane, clathrin-coated endocytic vesicle membrane, transport vesicle membrane, endosome membrane, and ER to Golgi transport vesicle membrane. This protein is part of integral component of membrane: integral component of membrane, and integral component of lumenal side of endoplasmic reticulum membrane. This protein enables the following function: peptide antigen binding.
MQAHELLQYFRLPELVDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVAGSDGARRSTLLDSDEPLVYFYDDVRTLYDVFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVEDLSECIGSALLQKGFQASPDQFIGIFAQNRPEWVIIEQACFAYSMVVVPLYDTLGADAITYIVNKAELSVIFADKPEKARILLESVENKLTPGLKIIVVMDSYGSELVEQGKKCGVEVISLKAMEGLGRANRRKPKPPEPDDLAVICFTSGTTGNPKGAMITHKNVVSDCSAFVKATEKALVLNASDIHISFLPLAHMYEQLLQCVMLCHGAKIGFFQGDIRLLMDDLKALQPTIFPVVPRLLNRMFDRIFAQANTTVKRWLLDFASKRKEAELRSGIIRNNSVWDKLIFHKIQSSLGGKVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCSLSVPGDWTAGHVGAPMPCNFIKLVDVEEMNYMAAMGEGEVCVKGPNVFKGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYVRSEPVAQVFVHGESLQAFLIAIVVPDAESLASWARKRGFEGSFEELCRNKDVKKAILEDMVRIGKDSGLKSFEQVRGIALHPELFSVDNGLLTPTMKAKRPELRNYFRSQIDELYSTIKV	This protein is part of the following components: membrane, mitochondrion, peroxisomal membrane, organelle membrane, mitochondrial outer membrane, endoplasmic reticulum, peroxisome, endoplasmic reticulum membrane, and intracellular membrane-bounded organelle. This protein is involved in the following processs: long-chain fatty acid metabolic process, lipid metabolic process, fatty acid metabolic process, and very long-chain fatty acid metabolic process. This protein is located in the following components: intracellular membrane-bounded organelle, peroxisomal membrane, mitochondrial outer membrane, peroxisome, membrane, endoplasmic reticulum, endoplasmic reticulum membrane, and mitochondrion. This protein enables catalytic activity: catalytic activity, phytanate-CoA ligase activity, arachidonate-CoA ligase activity, decanoate-CoA ligase activity, long-chain fatty acid-CoA ligase activity, and ligase activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of membrane: organelle membrane, endoplasmic reticulum membrane, peroxisomal membrane, membrane, and mitochondrial outer membrane. This protein is part of mitochondrion: mitochondrion. This protein is involved in lipid metabolic process: very long-chain fatty acid metabolic process, lipid metabolic process, long-chain fatty acid metabolic process, and fatty acid metabolic process. This protein enables the following functions: ATP binding, nucleotide binding, pristanate-CoA ligase activity, catalytic activity, ligase activity, phytanate-CoA ligase activity, long-chain fatty acid-CoA ligase activity, arachidonate-CoA ligase activity, decanoate-CoA ligase activity, and long-chain fatty acid-CoA ligase activity.
MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNKFGLDKIYEGQVEVTGDEYNVESVDGKPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNITPDGMEEMYKKAHAAIRDNPVHEKKPKREVKKKRVNSTKMSLAQKKDRVAQKKASFLRAQERAADS	This protein is part of the following components: nucleolus, ribosome, ribonucleoprotein complex, endoplasmic reticulum, cytosol, cytosolic large ribosomal subunit, cytoplasm, protein-containing complex, synapse, nucleus, and nucleoplasm. This protein is involved in the following processs: positive regulation of translation, rRNA processing, negative regulation of ubiquitin-dependent protein catabolic process, translation, protein stabilization, negative regulation of ubiquitin protein ligase activity, regulation of signal transduction by p53 class mediator, negative regulation of protein neddylation, positive regulation of gene expression, ribosomal large subunit biogenesis, and ribosomal large subunit assembly. This protein is located in the following components: nucleoplasm, synapse, nucleus, endoplasmic reticulum, ribosome, cytoplasm, cytosol, nucleolus, and cytosolic ribosome. This protein is involved in metabolic process: rRNA processing. This protein enables RNA binding: 5S rRNA binding, rRNA binding, mRNA 5'-UTR binding, mRNA 3'-UTR binding, and RNA binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in translation: translation. This protein enables structural constituent of ribosome: structural constituent of ribosome. This protein is part of ribosome: ribosome. This protein enables the following functions: 5S rRNA binding, mRNA 3'-UTR binding, rRNA binding, ubiquitin ligase inhibitor activity, ubiquitin protein ligase binding, structural constituent of ribosome, mRNA 5'-UTR binding, and RNA binding.
HAAFTVAHEIGHLLGLSHDDSKFCEENFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQIPGPEELPGQTYDASQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPKNNGRYCTGK	This protein is part of the following component: extracellular region. This protein is involved in the following processs: proteolysis, myoblast fusion, and extracellular matrix disassembly. This protein is located in the following component: extracellular region. This protein enables hydrolase activity: metalloendopeptidase activity, metallopeptidase activity, hydrolase activity, and peptidase activity. This protein enables metal ion binding: metal ion binding. This protein is part of extracellular region: extracellular region. This protein is involved in proteolysis: proteolysis. This protein enables the following functions: metal ion binding, peptidase activity, metalloendopeptidase activity, metallopeptidase activity, hydrolase activity, and endopeptidase activity.
MEPAGPAPGRLGPLLLCLLLSASCFCTGATGKELKVTQPEKSVSVAAGDSTVLNCTLTSLLPVGPIRWYRGVGPSRLLIYSFAGEYVPRIRNVSDTTKRNNMDFSIRISNVTPADAGIYYCVKFQKGSSEPDTEIQSGGGTEVYVLAKPSPPEVSGPADRGIPDQKVNFTCKSHGFSPRNITLKWFKDGQELHPLETTVNPSGKNVSYNISSTVRVVLNSMDVNSKVICEVAHITLDRSPLRGIANLSNFIRVSPTVKVTQQSPTSMNQVNLTCRAERFYPEDLQLIWLENGNVSRNDTPKNLTKNTDGTYNYTSLFLVNSSAHREDVVFTCQVKHDQQPAITRNHTVLGFAHSSDQGSMQTFPDNNATHNWNVFIGVGVACALLVVLLMAALYLLRIKQKKAKGSTSSTRLHEPEKNAREITQVQSLIQDTNDINDITYADLNLPKEKKPAPRAPEPNNHTEYASIETGKVPRPEDTLTYADLDMVHLSRAQPAPKPEPSFSEYASVQVQRK	This protein is part of the following components: membrane, integral component of membrane, cell surface, integral component of plasma membrane, and plasma membrane. This protein is involved in the following processs: cellular response to lipopolysaccharide, negative regulation of chemokine (C-C motif) ligand 5 production, positive regulation of phagocytosis, regulation of tumor necrosis factor production, positive regulation of T cell activation, granulocyte migration, negative regulation of ERK1 and ERK2 cascade, regulation of gene expression, negative regulation of JNK cascade, negative regulation of cytokine production involved in inflammatory response, regulation of catalytic activity, negative regulation of nitric oxide biosynthetic process, negative regulation of inflammatory response, negative regulation of I-kappaB phosphorylation, negative regulation of tumor necrosis factor production, negative regulation of phagocytosis, regulation of interferon-gamma production, negative regulation of interleukin-6 production, positive regulation of cell-cell adhesion, cellular response to interleukin-12, negative regulation of protein phosphorylation, heterotypic cell-cell adhesion, cell-cell adhesion, negative regulation of interferon-beta production, and negative regulation of macrophage inflammatory protein 1 alpha production. This protein acts upstream of or within the following processs: cellular response to interferon-gamma, monocyte extravasation, positive regulation of phagocytosis, cell migration, cellular response to interleukin-12, cell-matrix adhesion, actin filament organization, regulation of interferon-gamma production, cellular response to hydrogen peroxide, phagocytosis, engulfment, cytoskeleton organization, regulation of interleukin-6 production, regulation of nitric oxide biosynthetic process, regulation of tumor necrosis factor production, hematopoietic progenitor cell differentiation, regulation of interleukin-1 beta production, regulation of gene expression, negative regulation of phagocytosis, negative regulation of inflammatory response, cellular response to interleukin-1, and phagocytosis, recognition. This protein is active in the following component: plasma membrane. This protein is located in the following components: membrane, cell surface, plasma membrane, integral component of plasma membrane, and integral component of membrane. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of plasma membrane, and integral component of membrane. This protein enables the following functions: SH3 domain binding, GTPase regulator activity, cell-cell adhesion mediator activity, protein tyrosine kinase binding, protein binding involved in heterotypic cell-cell adhesion, protein phosphatase binding, protein phosphorylated amino acid binding, protein binding, and protein antigen binding.
MTDLPASVRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMIIVSYVLTVAVMLPASGWLADRVGVRNIFFTAIVLFTAGSLFCAQASTLDQLVMARVLQGVGGAMMVPVGRLTVMKIVPRDQYMAAMTFVTLPGQVGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAIATLCLMPNYTMQTRRFDLSGFLLLAAGMATLTLALDGQKGLGISPAWLAGLVAVGLCALLLYLWHARGNARALFSLNLFRNRTFSLGLGGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVASTLGLAAVSLLFMFSALAGWYYVLPLVLFLQGMINASRFSSMNTLTLKDLPDDLASSGNSLLSMVMQLSMSIGVTIAGLLLGLYGQQHMSLDAASTHQVFLYTYLSMAAIIALPALIFSRVPDDVGSNTVLRRRNRSGS	This protein is part of the following components: integral component of plasma membrane, membrane, integral component of membrane, and plasma membrane. This protein is involved in the following process: transmembrane transport. This protein is located in the following components: integral component of membrane, plasma membrane, integral component of plasma membrane, and membrane. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane, and integral component of plasma membrane. This protein is involved in transmembrane transport: transmembrane transport. This protein enables the following function: transmembrane transporter activity.
MGTKPTEQVSWGLYSGYDEEAYSVGPLPELCYKADVQAFSRAFQPSVSLMVAVLGLAGNGLVLATHLAARRTTRSPTSVHLLQLALADLLLALTLPFAAAGALQGWNLGSTTCRAISGLYSASFHAGFLFLACISADRYVAIARALPAGQRPSTPSRAHLVSVFVWLLSLFLALPALLFSRDGPREGQRRCRLIFPESLTQTVKGASAVAQVVLGFALPLGVMAACYALLGRTLLAARGPERRRALRVVVALVVAFVVLQLPYSLALLLDTADLLAARERSCSSSKRKDLALLVTGGLTLVRCSLNPVLYAFLGLRFRRDLRRLLQGGGCSPKPNPRGRCPRRLRLSSCSAPTETHSLSWDN	This protein is part of the following components: external side of plasma membrane, membrane, integral component of membrane, endoplasmic reticulum, cell surface, plasma membrane, and integral component of plasma membrane. This protein is involved in the following processs: cell chemotaxis, chemotaxis, chemokine-mediated signaling pathway, calcium-mediated signaling, immune response, signal transduction, G protein-coupled receptor signaling pathway, and positive regulation of cytosolic calcium ion concentration. This protein acts upstream of or within the following processs: chemotaxis, and positive regulation of cytosolic calcium ion concentration. This protein is active in the following component: external side of plasma membrane. This protein is located in the following components: cell surface, integral component of plasma membrane, plasma membrane, endoplasmic reticulum, membrane, and integral component of membrane. This protein is involved in signal transduction: calcium-mediated signaling, signal transduction, chemokine-mediated signaling pathway, and G protein-coupled receptor signaling pathway. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of membrane, and integral component of plasma membrane. This protein enables the following functions: C-C chemokine binding, chemokine binding, protein binding, chemokine receptor activity, G protein-coupled receptor activity, and C-C chemokine receptor activity.
MAEESNKLAFPSVVDRYFTRWYKPDIKGKPCEDHCILQHSNRICIITLAECHPLLQNEKTIKSISYQISANCSRLQNKVSGKSKRGAQFLTELAPLCRISSTDGEEYTIYSCIRGRLLEVNENILQNPGLLKEKPSTEGYIAVVLPKFEESKTITEGLLSQREYEEIVQSRAALRSETVQAVY	This protein is part of the following components: nucleus, cell projection, dendrite, lamellipodium, filopodium tip, growth cone, and nuclear speck. This protein is involved in the following processs: regulation of filopodium assembly, regulation of actin filament polymerization, and dendrite morphogenesis. This protein is located in the following components: lamellipodium, growth cone, nuclear speck, cell projection, dendrite, nucleus, and filopodium tip. This protein is part of nucleus: nucleus.
MIPGNRMLMVILLCQVLLGGTNHASLIPETGRKKVAELQGQAGSGRRSAQSHELLRGFETTLLQMFGLRRRPQPSKSAVIPSYMLDLYRLQSGEEEERSLQEISLQYPERSASRANTVRSFHHEEHLESVPGPSEAPRIRFVFNLSSVPDNEVISSEELRLYREQVEEPSAAWERGFHRINIYEVMKPLSERSQAITRLLDTRLVHHNVTRWETFDVSPAVIRWTKDKQPNHGLVIEVTHLHQAQTHQGKHVRISRSLPQGHGGDWAQLRPLLVTFGHDGRGHALTRRARRSPKHHGSRKNKKNCRRHALYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR	This protein is part of the following components: extracellular space, and extracellular region. This protein is involved in the following processs: negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of epidermal cell differentiation, nephric duct formation, positive regulation of progesterone secretion, embryonic skeletal system morphogenesis, beak formation, ureteric bud morphogenesis, SMAD protein signal transduction, mesenchymal cell proliferation involved in ureteric bud development, mesenchymal cell proliferation involved in ureter development, regulation of myotome development, cartilage development, polarity specification of dorsal/ventral axis, positive regulation of transcription, DNA-templated, intermediate mesodermal cell differentiation, ossification, beak morphogenesis, cell differentiation, cloacal septation, negative regulation of apoptotic process, multicellular organism development, and regulation of cell fate commitment. This protein is active in the following component: extracellular space. This protein is located in the following components: extracellular region, and extracellular space. This protein is involved in signal transduction: SMAD protein signal transduction, and BMP signaling pathway. This protein is part of extracellular region: extracellular region. This protein is involved in regulation of transcription, DNA-templated: negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, and positive regulation of transcription, DNA-templated. This protein enables the following functions: cytokine activity, BMP receptor binding, protein binding, and growth factor activity.
MATNYNEKLLLNYVPVYVMLPLGVVNVENVFADPETLETQLKRLKEEAGVDGVMVDVWWGIIESKGPKQYDWTAYKTLFQLIARLGLKIQAIMSFHQCGGNVGDIVTIPIPQWVRDVGDNDPDIYYTNRKGTRDIEYLSIGVDNLPLFAGRTAVQLYSDYMSSFKENMADLIEAGVIVDIEVGLGPAGELRYPSYPQSQGWVFPGIGEFQCYDKYLKKDFKEAAAKAGHPEWDLPEDAGEYNDKPEETGFFKKDGTYVSEKGKFFMTWYSNKLIFHGDQILGEANKIFAGLKVNLAAKVSGIHWLYNHHSHAAELTAGYYNLFKRDGYRPIARMLSKHYGILNFTCLEMKDTDNTAEALSAPQELVQEVLSKAWKEGIEVAGENALETYGAKGYNQILLNARPNGVNPNGKPKLRMYGFTYLRLSDTVFQENNFELFKKLVRKMHADQDYCGDAAKYGHEIVPLKTSNSQLTLEDIADAAQPSGAFKWDSETDLKVDG	This protein is part of the following components: cytoplasm, cytosol, and secretory vesicle. This protein is involved in the following processs: carbohydrate metabolic process, starch catabolic process, polysaccharide catabolic process, response to herbivore, and metabolic process. This protein is located in the following components: cytoplasm, secretory vesicle, and cytosol. This protein enables hydrolase activity: beta-amylase activity, hydrolase activity, acting on glycosyl bonds, hydrolase activity, and amylopectin maltohydrolase activity. This protein is involved in metabolic process: metabolic process. This protein is part of cytoplasm: cytoplasm. This protein is part of cytosol: cytosol. This protein is involved in carbohydrate metabolic process: polysaccharide catabolic process, starch catabolic process, and carbohydrate metabolic process. This protein enables the following functions: amylopectin maltohydrolase activity, beta-amylase activity, hydrolase activity, and hydrolase activity, acting on glycosyl bonds.
MARISHQGAAKPFTAWTTIFYLLLVFIAPLAFFGTAHAQDETSPQESYGTVIGIDLGTTYSCVGVMQNGKVEILVNDQGNRITPSYVAFTDEERLVGDAAKNQYAANPRRTIFDIKRLIGRKFDDKDVQKDAKHFPYKVVNKDGKPHVKVDVNQTPKTLTPEEVSAMVLGKMKEIAEGYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRVVNEPTAAAIAYGLDKTGDERQVIVYDLGGGTFDVSLLSIDNGVFEVLATAGDTHLGGEDFDQRVMDHFVKLYNKKNNVDVTKDLKAMGKLKREVEKAKRTLSSQMSTRIEIEAFHNGEDFSETLTRAKFEELNMDLFKKTLKPVEQVLKDAKVKKSEVDDIVLVGGSTRIPKVQALLEEFFGGKKASKGINPDEAVAFGAAVQGGVLSGEEGTGDVVLMDVNPLTLGIETTGGVMTKLIPRNTVIPTRKSQIFSTAADNQPTVLIQVYEGERSLTKDNNLLGKFELTGIPPAPRGVPQIEVSFDLDANGILKVHASDKGTGKAESITITNDKGRLSQEEIDRMVAEAEEFAEEDKAIKAKIEARNTLENYAFSLKNQVNDENGLGGQIDEDDKQTILDAVKEVTEWLEDNAATATTEDFEEQKEQLSNVAYPITSKLYGSAPADEDDEPSGHDEL	This protein is part of the following components: endoplasmic reticulum lumen, and endoplasmic reticulum. This protein is involved in the following process: response to unfolded protein. This protein is located in the following components: endoplasmic reticulum lumen, and endoplasmic reticulum. This protein enables hydrolase activity: hydrolase activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein enables the following functions: hydrolase activity, ATP binding, and nucleotide binding.
MSAEKTENLSWIDKRFPLSETWRNHLSEYYAPKNLNFWSFFGSLAILTLVIQIVTGVWLAMSYKPDAGLAFASVEYIMRDVDWGWLIRYMHSTGASMFFIVIYLHMFRGLLWGSYRKPRELLWMIGVVIYLVMMATAFFGYLLPWGQMSYWGAQVIVNLFAAVPVVGEDLSVWVRGDFVISDATLNRFFAFHFLLPFLLAGLVFLHIVALHHVGSNNPDGIEIKEGPKGNRWSDKAPADGIPFHPYYTVKDLMGVVVFLAIFGYVMFFNPTMGGLFLEAPNFQPANPMQTPAHIAPVWYFTPFYAMLRAVPPMYGSQFPGVVVMFAAILILFVLPWLDRSPVKSMRYKGPIFKWATGIFVVSFVALAWLGIQPASDFYTLLSQIFTVLYFAYFLLMPIYSSLDKTKPVPERVTS	This protein is part of the following components: integral component of membrane, membrane, respirasome, plasma membrane, and respiratory chain complex III. This protein is involved in the following process: respiratory electron transport chain. This protein is located in the following components: membrane, integral component of membrane, respirasome, and plasma membrane. This protein is involved in metabolic process: respiratory electron transport chain. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: ubiquinol-cytochrome-c reductase activity, oxidoreductase activity, and electron transfer activity. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of mitochondrion: mitochondrion. This protein enables the following functions: oxidoreductase activity, electron transfer activity, metal ion binding, and ubiquinol-cytochrome-c reductase activity.
MSSPTSTPSRRKSKRGRGSNPPTPRGEEVQSPPSQKRRTEDSTSIGELLPMPTSPSGDIQSPLFSSPAPSRHSAHQSELDLSSPLTYGTPSSRVEGTPRSGIRGTPARQRADLGSARKVKQVDLHSDQPAAEELVTSEQSLGQKLVIWGTDVNVAICKEKFQRFVQRFIDPLAKEEENVGLDLNEPIYMQRLEEINVVGEPFLNIDCDHLRSFDQDLYRQLVCYPQEVIPTFDMAANEIFFERYPDSILEHQIQVRPYNALKTRNMRSLNPEDIDQLITISGMVIRTSQIIPEMQESFFKCQVCAFTTRVEIDRGRIAEPSVCKHCNTTHSMALIHNRSMFSDKQMIKLQESPEDMPAGQTPHTTILYAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVRNVKSVYKTHIDVIHYRKTDSKRLHGIDEDTEQKMFTEERVAVLKELAAKPDIYERLAAALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEVNILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPVESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDETYDRRLAHHLVALYYQSEEQLKEEHLDMAVLKDYIAYARTYVNPRLGEEASQALIEAYVDMRKIGSGRGMVSAYPRQLESLIRLSEAHAKVRFSSKVETIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATARKRKEELAQVLKKLIQSKGKTPAFKYQQLFEDLRGQSDAAITKDMFDEALHALADEDYLTVTGKTVRLL	This protein is part of the following components: MCM complex, nucleus, chromatin, and CMG complex. This protein is involved in the following processs: DNA duplex unwinding, DNA replication, cell cycle, DNA unwinding involved in DNA replication, DNA replication initiation, and regulation of DNA-dependent DNA replication initiation. This protein contributes to the following functions: chromatin binding, and ATP hydrolysis activity. This protein is located in the following components: chromosome, chromatin, and nucleus. This protein enables hydrolase activity: ATP hydrolysis activity, and hydrolase activity. This protein is involved in metabolic process: DNA replication initiation, and DNA replication. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: helicase activity, and DNA helicase activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein enables DNA binding: DNA binding. This protein is part of nucleus: nucleus. This protein is involved in cell cycle: cell cycle. This protein enables the following functions: ATP binding, metal ion binding, DNA helicase activity, hydrolase activity, chromatin binding, helicase activity, nucleotide binding, and DNA binding.
MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGEKIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQNGAKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRLILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAAEGYICKGLSFSPITGGDGNIEFLLHLHWPGEGQEGQELPEEEIMRVVEEAHKTLKEKKADVPE	This protein is involved in the following processs: rRNA processing, and methylation. This protein is involved in metabolic process: rRNA processing. This protein enables RNA binding: RNA binding. This protein enables transferase activity: methyltransferase activity, and transferase activity. This protein is involved in methylation: methylation. This protein enables the following functions: transferase activity, RNA binding, and methyltransferase activity.
MKLNVDGLLVYFPYDYIYPEQFSYMLELKRTLDAKGHGVLEMPSGTGKTVSLLALIVAYQRAFPLEVTKLIYCSRTVPEIEKVIEELRKLLSFYEQQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQQDASLPHCRFYEEFDAHGRQVPLPAGIYNLDDLKALGQRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQSNLDTLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEIADLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARADKRGKLPRWIQEHLTDSNLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLQSEETLRRVEQIAQQL	This protein is part of the following components: cytoplasm, transcription factor TFIIH holo complex, spindle, CAK-ERCC2 complex, MMXD complex, cytoskeleton, and nucleus. This protein is involved in the following processs: chromosome segregation, apoptotic process, nucleotide-excision repair, nucleobase-containing compound metabolic process, multicellular organism growth, post-embryonic development, hair cycle process, DNA duplex unwinding, hair follicle maturation, hematopoietic stem cell differentiation, hair cell differentiation, regulation of mitotic cell cycle phase transition, erythrocyte maturation, nucleotide-excision repair, DNA incision, spinal cord development, DNA repair, cellular response to DNA damage stimulus, bone mineralization, skin development, extracellular matrix organization, response to oxidative stress, UV protection, aging, central nervous system myelin formation, ribosomal small subunit biogenesis, cell population proliferation, in utero embryonic development, transcription-coupled nucleotide-excision repair, response to UV, positive regulation of DNA binding, and transcription by RNA polymerase II. This protein is located in the following components: cytoskeleton, cytoplasm, nucleus, and spindle. This protein enables hydrolase activity: hydrolase activity, and hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides. This protein is involved in metabolic process: nucleotide-excision repair, DNA incision, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), transcription by RNA polymerase II, transcription elongation from RNA polymerase I promoter, and nucleobase-containing compound metabolic process. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: 5'-3' DNA helicase activity, DNA helicase activity, and helicase activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is involved in cellular response to DNA damage stimulus: transcription-coupled nucleotide-excision repair, cellular response to DNA damage stimulus, DNA repair, and nucleotide-excision repair. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: positive regulation of transcription, DNA-templated, and positive regulation of transcription by RNA polymerase II. This protein is involved in cell division: embryonic cleavage. This protein enables the following functions: iron-sulfur cluster binding, nucleotide binding, DNA helicase activity, metal ion binding, 5'-3' DNA helicase activity, nucleic acid binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, 4 iron, 4 sulfur cluster binding, protein C-terminus binding, helicase activity, ATP binding, hydrolase activity, protein N-terminus binding, and DNA binding.
MDCPIPQTELDEIYAFATDLARKAGQLLLERVNDRNSEQVYAEKENAVDLVTQTDEDVESLIKTAIQTKYPAHKFLGEESYAKGQSREYLIDEQPTWCVDPLDGTVNFTHAFPMFCVSIGFIVNHYPVIGVIYAPMLNQLFSSCLNRGAWLNEMQQLPLIRKPSIPPLPATAPSKCIFACEWGKDRRDIPDGTLQRKIESFVNMAAERGSRGGKGGMVHGVRSLGSATMDLAYTAMGSVDIWWEGGCWEWDVAAGIAILLEAGGLVTAANPPEDIEGPIEPVKLGSRLYLAIRPAGPSETETGRETQERTVREVWRRVRQLDYERPTRQS	This protein is part of the following component: cellular_component. This protein is involved in the following processs: inositol metabolic process, quinate metabolic process, inositol phosphate dephosphorylation, signal transduction, phospholipid metabolic process, and phosphatidylinositol phosphate biosynthetic process. This protein is active in the following component: cellular_component. This protein enables hydrolase activity: inositol phosphate phosphatase activity, and inositol monophosphate 1-phosphatase activity. This protein is involved in signal transduction: signal transduction. This protein is involved in metabolic process: quinate metabolic process. This protein enables metal ion binding: metal ion binding. This protein is involved in lipid metabolic process: phospholipid metabolic process, and phosphatidylinositol phosphate biosynthetic process. This protein is involved in carbohydrate metabolic process: inositol phosphate dephosphorylation, and inositol metabolic process. This protein enables the following functions: inositol monophosphate 1-phosphatase activity, inositol phosphate phosphatase activity, and metal ion binding.
MPRTSLLTLACALATGASAFSYGAAIPQSTQEKQFSQEFRDGYSILKHYGGNGPYSERVSYGIARDPPTSCEVDQVIMVKRHGERYPSPSAGKDIEEALAKVYSINTTEYKGDLAFLNDWTYYVPNECYYNAETTSGPYAGLLDAYNHGNDYKARYGHLWNGETVVPFFSSGYGRVIETARKFGEGFFGYNYSTNAALNIISESEVMGADSLTPTCDTDNDQTTCDNLTYQLPQFKVAAARLNSQNPGMNLTASDVYNLMVMASFELNARPFSNWINAFTQDEWVSFGYVEDLNYYYCAGPGDKNMAAVGAVYANASLTLLNQGPKEAGSLFFNFAHDTNITPILAALGVLIPNEDLPLDRVAFGNPYSIGNIVPMGGHLTIERLSCQATALSDEGTYVRLVLNEAVLPFNDCTSGPGYSCPLANYTSILNKNLPDYTTTCNVSASYPQYLSFWWNYNTTTELNYRSSPIACQEGDAMD	This protein is involved in the following process: dephosphorylation. This protein enables hydrolase activity: 3-phytase activity, phosphatase activity, and hydrolase activity. This protein is involved in metabolic process: dephosphorylation. This protein enables the following functions: phosphatase activity, hydrolase activity, and 3-phytase activity.
MNYEVVIPAAGQGKRMNAGKNKLFIEAKGIPVIIHTLKVFENHDACKRIILVINEQEFGEFNTLLKTYHFKTPIEMVPGGRERQQSVFAGIKAAGKEETVLVHDGARPFIKREYIEQLVEKAKETGAAIVAVPVKDTIKRVQDGEIAGTIERSSLWAAQTPQAFRLSILMNAHLEAEAKGFLGTDDASLVEEAGGTVAIIQGDYQNIKLTTPDDLLVAEAILEAEKRNEHV	This protein is involved in the following processs: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway, isoprenoid biosynthetic process, and terpenoid biosynthetic process. This protein enables catalytic activity: catalytic activity. This protein enables transferase activity: cytidylyltransferase activity, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity, nucleotidyltransferase activity, and transferase activity. This protein is involved in lipid metabolic process: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway, isoprenoid biosynthetic process, and terpenoid biosynthetic process. This protein enables the following functions: nucleotidyltransferase activity, transferase activity, catalytic activity, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity, and cytidylyltransferase activity.
MEHFQQVEPFDYVIFGATGDLTMRKLLPALYNRLRMGQIPDDACIIGAARTELDREAYVARARDALERFLPSDILGPGLVERFLARLDYVTLDSSREGPQWDALKSLLAKAQPDRVRVYYFATAPQLYGSICENLNRYELITPTSRVVLEKPIGTNMATATAINDGVGQYFPEKQIYRIDHYLGKETVQNVLALRFANPLMNAAWSGEHIESVQITAVETVGVEGRAAYYDTSGALRDMIQNHLLQVLCLVAMEAPDSLEADAVRNAKLAVLNALRPITDATAATETVRAQYTAGVVDGENVPGYLEELGKPSATETYAAIRAWVDTPRWKNVPFYIRTAKRSGKKVSEIVVTFRPAATTMFGATPASNRLVLRIQPNEGVDLRLNVKNPALDVFNLRTADLDTSIRMEGGLPFPDSYERLLLDAVRGDPVLFIRRDEVEAAWRWVEPILEAWKHDKAPMQTYSAGSYGPEQATQLLASHGDTWHEASE	This protein is involved in the following processs: carbohydrate metabolic process, pentose-phosphate shunt, and glucose metabolic process. This protein is involved in metabolic process: pentose-phosphate shunt. This protein enables catalytic activity: glucose-6-phosphate dehydrogenase activity, oxidoreductase activity, and oxidoreductase activity, acting on CH-OH group of donors. This protein enables nucleotide binding: NADP binding. This protein is involved in carbohydrate metabolic process: glucose metabolic process, and carbohydrate metabolic process. This protein enables the following functions: glucose-6-phosphate dehydrogenase activity, NADP binding, oxidoreductase activity, and oxidoreductase activity, acting on CH-OH group of donors.
MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVTKMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKVLCG	This protein is part of the following components: chromatin, nucleus, protein-containing complex, cytoplasm, cytosol, and euchromatin. This protein is involved in the following processs: epithelial cell differentiation involved in mammary gland alveolus development, circadian rhythm, regulation of cell cycle, positive regulation of smooth muscle cell proliferation, circadian regulation of gene expression, positive regulation of blood pressure, membranous septum morphogenesis, positive regulation of transcription, DNA-templated, positive regulation of gene expression, cellular senescence, cell differentiation, multicellular organism development, regulation of circadian rhythm, mammary gland epithelial cell proliferation, negative regulation of transcription by RNA polymerase II, negative regulation of muscle cell differentiation, negative regulation of core promoter binding, endodermal digestive tract morphogenesis, regulation of G1/S transition of mitotic cell cycle, embryonic digestive tract morphogenesis, rhythmic process, negative regulation of transcription, DNA-templated, locomotor rhythm, regulation of cell cycle, negative regulation of DNA-binding transcription factor activity, entrainment of circadian clock by photoperiod, mammary gland alveolus development, negative regulation of gene expression, and regulation of lipid metabolic process. This protein acts upstream of or within the following processs: negative regulation of oligodendrocyte differentiation, cellular response to lithium ion, cell maturation, thigmotaxis, regulation of G1/S transition of mitotic cell cycle, negative regulation of transcription, DNA-templated, enucleate erythrocyte differentiation, metanephros development, positive regulation of cell cycle, lymph node development, positive regulation of erythrocyte differentiation, olfactory bulb development, natural killer cell differentiation, adipose tissue development, negative regulation of gene expression, heart development, oligodendrocyte development, positive regulation of gene expression, negative regulation of B cell differentiation, leukocyte differentiation, regulation of lipid metabolic process, entrainment of circadian clock, negative regulation of osteoblast differentiation, bundle of His development, negative regulation of DNA binding, cell development, negative regulation of transcription by RNA polymerase II, cell morphogenesis involved in neuron differentiation, negative regulation of DNA-binding transcription factor activity, positive regulation of fat cell differentiation, adult locomotory behavior, positive regulation of cell population proliferation, negative regulation of neuron differentiation, Peyer's patch development, positive regulation of astrocyte differentiation, and positive regulation of macrophage differentiation. This protein colocalizes with the following component: cytoplasm. This protein acts upstream of the following process: neuron fate commitment. This protein is active in the following component: nucleus. This protein acts upstream of negative effect: regulation of gene expression, regulation of neural precursor cell proliferation, and regulation of neuron differentiation. This protein is located in the following components: chromatin, cytosol, euchromatin, cytoplasm, and nucleus. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in regulation of transcription, DNA-templated: negative regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, negative regulation of transcription, DNA-templated, and negative regulation of DNA-binding transcription factor activity. This protein enables the following functions: transmembrane transporter binding, transcription coactivator activity, RNA polymerase II-specific DNA-binding transcription factor binding, protein binding, RNA polymerase II-specific DNA-binding transcription factor binding, protein dimerization activity, and transcription regulator inhibitor activity.
MAWNTNLRGRLPITCLILQVTMVVLFGVFVRYDIQADAHWWLEKKRKNISSDVENEFYYRYPSFQDVHAMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHYFEEGHIVLSVENIIQADFCVASSCVAFGAVLGKVSPMQLLIMTFFQVTLFTVNEFILLNLIEAKDAGGSMTIHTFGAYFGLTVTWILYRKNLDQSKQRQSSVYHSDLFAMIGTLFLWIYWPSFNSASSFHGDAQHRAALNTYLSLAASVLTTVTVSSIVHKKGKLDMVHIQNATLAGGVGVGTAAEMMLTPYGALIVGFFCGIFSTLGFAYLTPFLESRHRIQDTCGIHNLHGIPGIIGGIVGAVTAAYSSPDVYGEPGIVHSFGFGSYKMDWNKRMQGRSQIFGLLLSLAMALVGGIIVGFILKLPFWGQAADENCFEDSIYWEVHEEVNTVYIPEDLAHKHSTSLVPAMPLVLPTTSASIVPPVPPTPPVSLATSAPSAALVH	This protein is part of the following components: integral component of plasma membrane, apical plasma membrane, cytoplasmic vesicle, plasma membrane, basolateral plasma membrane, membrane, basal plasma membrane, and integral component of membrane. This protein is involved in the following processs: cellular ion homeostasis, ammonium transmembrane transport, ammonium transport, transepithelial ammonium transport, and regulation of pH. This protein acts upstream of or within the following processs: cellular ion homeostasis, ammonium transport, and transepithelial ammonium transport. This protein is active in the following component: integral component of plasma membrane. This protein is located in the following components: basolateral plasma membrane, integral component of plasma membrane, plasma membrane, integral component of membrane, cytoplasmic vesicle, apical plasma membrane, membrane, and basal plasma membrane. This protein is part of membrane: apical plasma membrane, plasma membrane, basolateral plasma membrane, basal plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of plasma membrane, and integral component of membrane. This protein is involved in cation transport: ammonium transmembrane transport, and transepithelial ammonium transport. This protein enables the following functions: ammonium transmembrane transporter activity, identical protein binding, and ankyrin binding.
MSVNRCIYLLSRSHIRYRVCASTNLSTVSTLSTTQHSTRRTFDKLSTRHSSSGSSRPLDTSLFIPLPVKTDEDAEGSVGAELTKPLDKNELLKVLNRFYKRKEMQKLASDQGLDARLFHQAFVSFRKYVLEMNSLNADLHIILNDICCGAGHIDDIFPYFMRHAKQIFPMLDCIDDLRKISDLRVPANWYPEARAIQRKIVFHAGPTNSGKTYHAIKRYLEAKSGVYCGPLKLLAHEIYEKSNAAGVPCDLVTGEERIFVDPEGKPSGHIASTIEMCSVTTPYEVAVIDEIQMIKDPARGWAWTRALLGLCAEEIHVCGEAAAVDFITELMFTTGEEVEVHNYKRLTPFSISNHAVESLDNLKPGDCIVCFSKNDIYSISRQIEIRGLECAVIYGSLPPGTKLAQAKKFNDPDDPCKILVATDAIGMGLNLSIRRIIFNSLVKHSLNEKGEKEVDTISTSQALQIAGRAGRFSSVFKEGEVTTMHRDDLPVLKEILGKPVDPIATAGLHPTAEQIEMFAYHLPQATLSNLIDIFVSLSQVDGLYFVCNIDDFKFLADMIQHIPLNLRSRYVFCTAPINKKQPFVCTSFLKFARQFSRDEPLTFNWVCRQVNWPLSPPKNIKDLVHLEAVHDVLDLYLWLSYRFMDMFPDSNQIREIQKELDENIQIGVRNITRLIRAIDSQPTDTESNSSSTVPESETSQRKGRVLRSQNQRKELPRKSSLSSRLLRDGLLTKELLSQLQKEWAREQNEDNSIPVNNGKRKKK	This protein is part of the following components: mitochondrial matrix, nucleus, mitochondrion, mitochondrial degradosome, and mitochondrial nucleoid. This protein is involved in the following processs: DNA duplex unwinding, positive regulation of mitochondrial RNA catabolic process, chromatin maintenance, mitochondrial mRNA catabolic process, liver development, positive regulation of cell growth, mitochondrial RNA surveillance, mitochondrion morphogenesis, mitochondrial ncRNA surveillance, DNA recombination, RNA catabolic process, negative regulation of apoptotic process, mitochondrial mRNA surveillance, and mitochondrial RNA 3'-end processing. This protein is located in the following components: mitochondrion, nucleus, mitochondrial nucleoid, and mitochondrial matrix. This protein enables hydrolase activity: hydrolase activity, and hydrolase activity, acting on acid anhydrides. This protein is involved in metabolic process: DNA recombination, mitochondrial mRNA surveillance, mitochondrial RNA surveillance, mitochondrial RNA 3'-end processing, RNA catabolic process, mitochondrial mRNA catabolic process, and mitochondrial ncRNA surveillance. This protein enables catalytic activity: 3'-5' RNA helicase activity, helicase activity, RNA helicase activity, and DNA helicase activity. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of mitochondrion: mitochondrion. This protein enables RNA binding: double-stranded RNA binding. This protein enables DNA binding: DNA binding. This protein is part of nucleus: nucleus. This protein enables the following functions: DNA helicase activity, hydrolase activity, acting on acid anhydrides, 3'-5' RNA helicase activity, ATP binding, RNA helicase activity, helicase activity, nucleotide binding, hydrolase activity, double-stranded RNA binding, and DNA binding.
MSNGLVILHAGAGLYSGQREIQAKKTCSDACKAAIQALKVGQSALSAAIQAAKIMEDSPVTNAGVGSNLNIDGKVECEAGVMDSESGLTASVACCNCCRHPSEACLYILNKRKVMSQHGLVPPAMLVGNGIEKLLLHSNIKLVPESHLITERSMKTQIKWKEILYQNPINLSSQDTIGVICVDKNGRIAVVSSSGGLLLKPAGRIGSSPIPGHGFWIESFDNKSHSSTCAVATSGTGEHISNTCFACRSSQLLVSEDNVVSSLNKLINDFHEHPSATLYSDLQVGIIFAKVETSNSHNKRIIFGLAHSSPDMVFGFMKGDHSKPTTEISRKGSKRSSVQLYAERL	This protein is part of the following components: cytoplasm, and cytosol. This protein is involved in the following processs: protein maturation, protein processing, and proteolysis. This protein is active in the following component: cytoplasm. This protein is located in the following components: cytoplasm, and cytosol. This protein enables hydrolase activity: hydrolase activity, peptidase activity, and threonine-type endopeptidase activity. This protein is involved in metabolic process: protein maturation. This protein is part of cytoplasm: cytoplasm. This protein is involved in proteolysis: proteolysis, and protein processing. This protein is part of cytosol: cytosol. This protein enables the following functions: hydrolase activity, peptidase activity, and threonine-type endopeptidase activity.
MEINKFICSQGPKKNSCEDFWRMVLEQESCIIVSLTETDDEDQVCYEYWVKEEDYELAFGRYVVKTLEIIEESSFTRTRLRLTDVSSDTSREIHHFWYPHWSDYGNPTNPAEILNLISKVNQKRKEMKKTADSQPGPIVVHCSAGIGRTGTFCTIDNALSQLRKEQTVCLPQTVLKIQKSKI	This protein is involved in the following processs: peptidyl-tyrosine dephosphorylation, protein dephosphorylation, and dephosphorylation. This protein enables hydrolase activity: phosphoprotein phosphatase activity, hydrolase activity, phosphatase activity, and protein tyrosine phosphatase activity. This protein is involved in metabolic process: dephosphorylation, peptidyl-tyrosine dephosphorylation, and protein dephosphorylation. This protein enables the following functions: phosphoprotein phosphatase activity, hydrolase activity, phosphatase activity, and protein tyrosine phosphatase activity.
MAINTDTQYEKALGGSGNPLPADSHETEKLLTNASENKEENGMKKSFSVTMSSEKSMGDLEQNGHNLPYKSVSAGQLESAPLSPSRVSLARASSTATTAQEQGRPTDYLVLAIFSCFCPVWPVNIVALVFSIMSRNSLQQGDLDGARRLGRLARLLSVVSILLGLVIIVLCILSLTIFH	This protein is part of the following components: cytoplasm, perinuclear region of cytoplasm, cytoplasmic vesicle membrane, plasma membrane, membrane, integral component of membrane, and endomembrane system. This protein is involved in the following processs: cellular response to insulin stimulus, endosome to plasma membrane protein transport, protein localization to plasma membrane, and glucose import in response to insulin stimulus. This protein is active in the following component: membrane. This protein is located in the following components: membrane, endomembrane system, cytoplasm, integral component of membrane, plasma membrane, cytoplasmic vesicle membrane, and perinuclear region of cytoplasm. This protein is part of membrane: cytoplasmic vesicle membrane, membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of cytoplasm: cytoplasm. This protein is involved in transmembrane transport: glucose import in response to insulin stimulus. This protein is involved in protein transport: endosome to plasma membrane protein transport.
MAVTDIFARRATLARSVRLLSQFRYERSEPARFYGALAADTAAMVDDLWRAGHGESAAGRTLLDVGGGPGYFAAAFTDAGVRYLGVEPDPGEMHAAGPVVAADTGTFVRASGMALPFADDSVDICLSSNVAEHVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLTHYLGGARAAERYARKHGHPAKNNYGSSLFEVSVADGLAWAASTGAALAAFPRYHPRWAWSLTSVPVLREFLVSNLVLVLQPQ	This protein is involved in the following process: methylation. This protein enables transferase activity: transferase activity, and methyltransferase activity. This protein is involved in methylation: methylation. This protein enables the following functions: methyltransferase activity, and transferase activity.
MTSSVLTPSLKLLAMTNSSSSTLFCIPSIFNISSSESHRFNFSLSSRPVNLTLSLKSKTLRNSSPVVTFVSQTSNWAEEEEGEDGSIGGTSVTVDESFESEDGVGFPEPPEEAKLFVGNLPYDVDSQALAMLFEQAGTVEISEVIYNRDTDQSRGFGFVTMSTVEEAEKAVEKFNSFEVNGRRLTVNRAAPRGSRPERQPRVYDAAFRIYVGNLPWDVDSGRLERLFSEHGKVVDARVVSDRETGRSRGFGFVQMSNENEVNVAIAALDGQNLEGRAIKVNVAEERTRR	This protein is part of the following components: ribonucleoprotein complex, chloroplast, chloroplast thylakoid membrane, chloroplast stroma, chloroplast envelope, and plastid. This protein is involved in the following processs: mRNA processing, innate immune response, RNA modification, regulation of RNA metabolic process, and chloroplast rRNA processing. This protein is active in the following component: chloroplast thylakoid membrane. This protein is located in the following components: chloroplast, plastid, chloroplast stroma, and chloroplast envelope. This protein is involved in metabolic process: mRNA processing, RNA modification, and chloroplast rRNA processing. This protein is part of membrane: chloroplast thylakoid membrane. This protein enables RNA binding: RNA binding, mRNA binding, and poly(U) RNA binding. This protein is part of plastid: plastid, and chloroplast. This protein enables the following functions: RNA binding, mRNA binding, nucleic acid binding, and poly(U) RNA binding.
MWLLQPLLLCVPLSLAVHGQQKPQVPDYPGELHCGLQSLQFAINPSPGKATPALIVWDNRGLPHKLQNNSGCGTWVRESPGGSVLLDASYSSCYVNEWVSTTQSPGTSRPPTPASRVTPQDSHYVMIVGVEGTDAAGRRVTNTKVLRCPRNPPDQALVSSLSPSPLQNVALEAPNADLCDSVPKWDRLPCASSPITQGDCNKLGCCYKSEANSCYYGNTVTSRCTQDGHFSIAVSRNVTSPPLLLNSLRLAFGKDRECNPVKATRAFALFFFPFNSCGTTRWVTGDQAVYENELVAARDVRTWSHGSITRDSIFRLRVSCSYSVRSNAFPLSVQVFTIPPPHLKTQHGPLTLELKIAKDKHYGSYYTIGDYPVVKLLRDPIYVEVSIRHRTDPSLGLLLHNCWATPGKNSQSLSQWPILVKGCPYVGDNYQTQLIPVQKALDTPFPSYYKRFSIFTFSFVDTMAKWALRGPVYLHCNVSICQPAGTSSCRITCPVARRRRHSDLHHHSSTASISSKGPMILLQATMDSAEKLHKNSSSPIDSQALWMAGLSGTLIFGFLLVSYLAIRKRR	This protein is part of the following components: membrane, integral component of membrane, plasma membrane, extracellular region, and egg coat. This protein is involved in the following process: single fertilization. This protein is located in the following components: integral component of membrane, membrane, egg coat, plasma membrane, and extracellular region. This protein is part of membrane: plasma membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is part of extracellular region: extracellular region. This protein enables the following function: structural constituent of egg coat.
MNLYLLLGALAIFSLVYDKKENSIFLYLLILFLVFIIVSPAIISKNTESTVEDIPSHKAKSVRKKLEIEQALDAILNKNTSSID	This protein is part of the following components: host cell nucleus, host cell nuclear membrane, and host cell cytoplasm. This protein is located in the following components: host cell cytoplasm, host cell nuclear membrane, and host cell nucleus.
AVMGRNLALNIESRGYTVSVFNRSREKTEEVIAENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAETFTEWNKGELNSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEPLSLITESVFARYISSLKEQRVAASKVLSGPKAQLAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENAGIANLLLAPYFKKIADDYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRT	This protein is involved in the following processs: D-gluconate metabolic process, and pentose-phosphate shunt. This protein is involved in metabolic process: pentose-phosphate shunt. This protein enables catalytic activity: phosphogluconate dehydrogenase (decarboxylating) activity, and oxidoreductase activity. This protein enables nucleotide binding: NADP binding. This protein is involved in carbohydrate metabolic process: D-gluconate metabolic process. This protein enables the following functions: phosphogluconate dehydrogenase (decarboxylating) activity, oxidoreductase activity, and NADP binding.
MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSASAAAVSADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGEGDVHSMVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGTMMQQTPCYSFAPPNTSLNSPSPNYQKYTYGQSSMSPLPQMPIQTLQDNKSSYGGMSQYNCAPGLLKELLTSDSPPHNDIMTPVDPGVAQPNSRVLGQNVMMGPNSVMSTYGSQASHNKMMNPSSHTHPGHAQQTSAVNGRPLPHTVSTMPHTSGMNRLTQVKTPVQVPLPHPMQMSALGGYSSVSSCNGYGRMGLLHQEKLPSDLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG	This protein is part of the following components: cytosol, chromatin, nucleus, chromatin, cytoplasm, mitochondrion, and nucleoplasm. This protein is involved in the following processs: regulation of neural precursor cell proliferation, cellular response to oxidative stress, positive regulation of apoptotic process, negative regulation of cardiac muscle hypertrophy in response to stress, negative regulation of transcription, DNA-templated, regulation of cell population proliferation, insulin receptor signaling pathway, regulation of gluconeogenesis, cellular response to starvation, enamel mineralization, fat cell differentiation, regulation of transcription by RNA polymerase II, cellular response to dexamethasone stimulus, protein acetylation, negative regulation of canonical Wnt signaling pathway, temperature homeostasis, negative regulation of apoptotic process, neuronal stem cell population maintenance, response to insulin, positive regulation of protein catabolic process, cellular response to DNA damage stimulus, cellular response to hydrogen peroxide, cellular response to hyperoxia, cellular glucose homeostasis, cellular response to nitric oxide, cytokine-mediated signaling pathway, negative regulation of stress-activated MAPK cascade, positive regulation of autophagy, glucose homeostasis, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, regulation of reactive oxygen species metabolic process, regulation of type B pancreatic cell development, cellular response to insulin stimulus, energy homeostasis, positive regulation of gluconeogenesis, response to fatty acid, response to fluoride, blood vessel development, apoptotic process, positive regulation of transcription, DNA-templated, negative regulation of fat cell differentiation, autophagy, endocrine pancreas development, cellular response to cold, cell differentiation, and regulation of transcription, DNA-templated. This protein is active in the following component: nucleus. This protein is located in the following components: cytosol, nucleus, cytoplasm, mitochondrion, and nucleoplasm. This protein is involved in signal transduction: cytokine-mediated signaling pathway, and insulin receptor signaling pathway. This protein is involved in metabolic process: protein acetylation, and autophagy. This protein is involved in cellular response to DNA damage stimulus: cellular response to DNA damage stimulus. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein enables DNA binding: DNA binding, and sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in regulation of transcription, DNA-templated: negative regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, and negative regulation of transcription, DNA-templated. This protein enables the following functions: DNA-binding transcription activator activity, RNA polymerase II-specific, protein binding, ubiquitin protein ligase binding, transcription factor binding, promoter-specific chromatin binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, protein phosphatase 2A binding, DNA-binding transcription factor activity, RNA polymerase II-specific, sequence-specific DNA binding, DNA binding, chromatin binding, beta-catenin binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, and transcription coactivator binding.
MKITRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMGETQLCTTRCVLKELETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEEGNPHHYFVATQDQNLSVKVKKKPGVPLMFIIQNTMVLDKPSPKTIAFVKAVESGQLVSVHEKESIKHLKEEQGLVKNTEQSRRKKRKKISGPNPLSCLKKKKKAPDTQSSASEKKRKRKRIRNRSNPKVLSEKQNAEGE	This protein is part of the following components: nucleus, nucleolus, and small-subunit processome. This protein is involved in the following processs: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, and ribosome biogenesis. This protein is active in the following component: nucleolus. This protein is located in the following components: nucleus, and nucleolus. This protein is involved in metabolic process: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and rRNA processing. This protein enables RNA binding: mRNA 5'-UTR binding, small ribosomal subunit rRNA binding, RNA binding, and mRNA 3'-UTR binding. This protein is part of nucleus: nucleus. This protein enables the following functions: mRNA 3'-UTR binding, mRNA 5'-UTR binding, protein binding, RNA binding, and small ribosomal subunit rRNA binding.
MLDATLKSQLKTYLERVTQPIEIVASLDDGAKSRELHDLLVEIASLSNLITFSADGTDARRPSFSLNRPGADISLRFAGIPMGHEFTSLVLALLQVGGHPSKASAEVIEQIQALEGEFNFETYFSLSCQNCPDVVQALNLMAVLNPNVRHVAIDGALFQDEVESRKIMAVPSIYLNGEVFGQGRMGLEEILGKIDTNAGARQAEKINAKEAFDVLVVGGGPAGAAAAIYAARKGIRTGVAAERFGGQVLDTLAIENFISVQETEGPKLATALEEHVKQYDVDIMNLQRGEALIPAAEGGLHEVRLAGGASLKAKTVILATGARWREMNVPGEQEYRGRGVAYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVAQVTLIEFDSQLRADAVLQRKLRSLPNVNVITSALTTEVLGNGEKVTGLRYKDRSTDEQHEVALEGIFVQIGLLPNTDWLKGTVELSPRGEIIVDAKGQTSIPGVFAAGDVTTVPYKQIVIAVGEGAKASLAAFDHLIRTSAPA	This protein is involved in the following processs: response to reactive oxygen species, electron transport chain, and cell redox homeostasis. This protein is involved in metabolic process: electron transport chain. This protein enables catalytic activity: protein-disulfide reductase activity, electron transfer activity, alkyl hydroperoxide reductase activity, and oxidoreductase activity. This protein enables nucleotide binding: NAD binding, and flavin adenine dinucleotide binding. This protein enables the following functions: flavin adenine dinucleotide binding, oxidoreductase activity, alkyl hydroperoxide reductase activity, electron transfer activity, NAD binding, and protein-disulfide reductase activity.
MKVAVLGAGAWGTALAGHLAARHDTLLWARDAALIAGLQARHENSRYLDGIALPDALRYDADLGAALAHGAADDALCVIAAPVAGLRTLCHAMRDAGCVPAHVVWVCKGFEADTHLLPHQVIAAELPEQQSNGVLSGPSFAREVGRSLPVALTVASASAECRERTLAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGISDGLGLGLNARAALITRGLAEMSRLGVALGGRAETFTGLTGLGDLILTATGDLSRNRTVGLQLAAGRTLNDILGALGHVAEGVRCAQAVLALARAQSIDMPITQAVCGVLFDGIAPRDAVSGLLRRDARAE	This protein is part of the following components: glycerol-3-phosphate dehydrogenase complex, and cytoplasm. This protein is involved in the following processs: glycerol-3-phosphate metabolic process, glycerol-3-phosphate biosynthetic process, carbohydrate metabolic process, lipid metabolic process, phospholipid biosynthetic process, glycerophospholipid metabolic process, and glycerol-3-phosphate catabolic process. This protein is located in the following component: cytoplasm. This protein is involved in metabolic process: glycerol-3-phosphate biosynthetic process, glycerol-3-phosphate metabolic process, and glycerol-3-phosphate catabolic process. This protein enables catalytic activity: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, oxidoreductase activity, glycerol-3-phosphate dehydrogenase [NAD+] activity, and glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. This protein enables nucleotide binding: NAD binding. This protein is part of cytoplasm: cytoplasm. This protein is involved in lipid metabolic process: glycerophospholipid metabolic process, phospholipid biosynthetic process, and lipid metabolic process. This protein is involved in carbohydrate metabolic process: carbohydrate metabolic process. This protein enables the following functions: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, oxidoreductase activity, glycerol-3-phosphate dehydrogenase [NADP+] activity, glycerol-3-phosphate dehydrogenase [NAD+] activity, glycerol-3-phosphate dehydrogenase [NAD(P)+] activity, and NAD binding.
MTSFPTTPPPAEELMATTILQATEALSPEAEASTALIAVVITVVFLTLLSVVILIFFYLYKNKGSYVTYEPADGEPGAVVLMENDSAKGREKEEYFI	This protein is part of the following components: plasma membrane, cytoplasmic vesicle membrane, integral component of membrane, cytoplasmic vesicle, and membrane. This protein is located in the following components: cytoplasmic vesicle, cytoplasmic vesicle membrane, membrane, plasma membrane, and integral component of membrane. This protein is part of membrane: plasma membrane, cytoplasmic vesicle membrane, and membrane. This protein is part of integral component of membrane: integral component of membrane.
MPLSWLLPFSAMELLLTATIFYLVLWVVKAFRLQVPKGLKSPPGPWGWPLIGHVLTLGKNPHLALTRLSARYGDVLQIRIGSTPVVVLSGLDTIRQALVRQSDDFKGRPDLYSSTFISDGQSMIFNPDSGPVWAARRRLAQSALQSFSVASDPASVSSCYLEEHVSREAEHLVTKLLDLMAGPGCFEPSSQIVGSVANVIGAMCFGKNFPQTSEEMLQIVNTSKEFTEFASSGNPVDFFPILRYLPNPMLQQFKDFNKRFLQFLQKTVQEHYQDFDKNHVQDIASALFKHSEESPHVNGDLIPRKKIVNLVNDIFGAGFDTVTTAISWSLLYLVTKPEIQKKIHKELDAVIGRDRKPRLADRPQLPYMEAFILEVFRYSSFLPFTIPHCTTRDTILNGFYIPKDRCVFINQWQVNHDPKQWEDPFEFRPERFLLANNTAVDKTLSDKILLFGLGKRRCIGETLGRWEVFLFLAILLQQLEFSVPPGVKVDLTPVYGLTMKPPHCQHVQARPRFSK	This protein is part of the following components: endoplasmic reticulum membrane, endoplasmic reticulum, intracellular membrane-bounded organelle, organelle membrane, and membrane. This protein is involved in the following processs: estrogen metabolic process, fatty acid metabolic process, retinol metabolic process, steroid metabolic process, cholesterol metabolic process, arachidonic acid metabolic process, and lipid metabolic process. This protein is located in the following components: membrane, endoplasmic reticulum, endoplasmic reticulum membrane, and intracellular membrane-bounded organelle. This protein enables metal ion binding: iron ion binding, and metal ion binding. This protein enables catalytic activity: aromatase activity, hydroperoxy icosatetraenoate dehydratase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, estrogen 2-hydroxylase activity, lyase activity, monooxygenase activity, estrogen 16-alpha-hydroxylase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, and oxidoreductase activity. This protein is part of membrane: organelle membrane, endoplasmic reticulum membrane, and membrane. This protein is involved in lipid metabolic process: arachidonic acid metabolic process, estrogen metabolic process, lipid metabolic process, fatty acid metabolic process, retinol metabolic process, steroid metabolic process, and cholesterol metabolic process. This protein enables the following functions: iron ion binding, oxidoreductase activity, estrogen 16-alpha-hydroxylase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, estrogen 2-hydroxylase activity, aromatase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, heme binding, metal ion binding, lyase activity, monooxygenase activity, and hydroperoxy icosatetraenoate dehydratase activity.
MALLLVSLLAFLGTGSGCHHWLCHCSNRVFLCQDSKVTEIPTDLPRNAIELRFVLTKLRVIPKGSFAGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPSLRYLLISNTGIKHLPAVHKIQSLQKVLLDIQDNINIHIVARNSFMGLSFESVILWLSKNGIEEIHNCAFNGTQLDELNLSDNNNLEELPNDVFQGASGPVILDISRTKVHSLPNHGLENLKKLRARSTYRLKKLPNLDKFVTLMEASLTYPSHCCAFANLKRQISELHPICNKSILRQDIDDMTQIGDQRVSLIDDEPSYGKGSDMMYNEFDYDLCNEVVDVTCSPKPDAFNPCEDIMGYNILRVLIWFISILAITGNTTVLVVLTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLECKVQLRHAASVMVLGWTFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMALLVLNVLAFVVICGCYTHIYLTVRNPTIVSSSSDTKIAKRMATLIFTDFLCMAPISFFAISASLKVPLITVSKAKILLVLFYPINSCANPFLYAIFTKNFRRDFFILLSKFGCYEMQAQIYRTETSSATHNFHARKSHCSSAPRVTNSYVLVPLNHSSQN	This protein is part of the following components: integral component of membrane, endosome, membrane, plasma membrane, integral component of plasma membrane, cell surface, and receptor complex. This protein is involved in the following processs: regulation of MAPK cascade, activation of adenylate cyclase activity, Sertoli cell proliferation, locomotory behavior, regulation of acetylcholine metabolic process, regulation of protein phosphorylation, sperm chromatin condensation, adenylate cyclase-activating G protein-coupled receptor signaling pathway, follicle-stimulating hormone signaling pathway, ovulation cycle process, primary ovarian follicle growth, uterus development, spermatogenesis, cellular response to follicle-stimulating hormone stimulus, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, positive regulation of intracellular estrogen receptor signaling pathway, regulation of osteoclast differentiation, signal transduction, regulation of systemic arterial blood pressure, regulation of protein kinase A signaling, regulation of platelet-derived growth factor receptor signaling pathway, spermatid development, male gonad development, cellular water homeostasis, phospholipase C-activating G protein-coupled receptor signaling pathway, regulation of hormone metabolic process, ovarian follicle development, spermatogenesis, exchange of chromosomal proteins, G protein-coupled receptor signaling pathway, regulation of intracellular estrogen receptor signaling pathway, positive regulation of ERK1 and ERK2 cascade, negative regulation of bone resorption, basement membrane organization, neuron projection development, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, regulation of chromosome organization, hormone-mediated signaling pathway, Sertoli cell development, transcytosis, and positive regulation of phosphatidylinositol 3-kinase signaling. This protein is active in the following component: integral component of plasma membrane. This protein is located in the following components: endosome, integral component of membrane, membrane, cell surface, and plasma membrane. This protein is involved in signal transduction: adenylate cyclase-modulating G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, phospholipase C-activating G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, hormone-mediated signaling pathway, signal transduction, and follicle-stimulating hormone signaling pathway. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of plasma membrane, and integral component of membrane. This protein enables the following functions: protein-hormone receptor activity, follicle-stimulating hormone receptor activity, peptide hormone binding, G protein-coupled peptide receptor activity, protein binding, and G protein-coupled receptor activity.
MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGLEVPGDIKGETCSAKQHLDPHRNGETKADDSSNKEAAEEKQEEDGDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL	This protein is part of the following components: PRC1 complex, PcG protein complex, nucleus, X chromosome, and nucleoplasm. This protein is involved in the following processs: regulation of transcription by RNA polymerase II, inactivation of X chromosome by genetic imprinting, and histone H2A-K119 monoubiquitination. This protein colocalizes with the following component: X chromosome. This protein is located in the following components: X chromosome, nucleoplasm, and nucleus. This protein is involved in metabolic process: inactivation of X chromosome by genetic imprinting, and histone H2A-K119 monoubiquitination. This protein enables metal ion binding: metal ion binding. This protein enables DNA binding: RNA polymerase II transcription regulatory region sequence-specific DNA binding. This protein is part of nucleus: nucleus. This protein is involved in regulation of transcription, DNA-templated: regulation of transcription, DNA-templated. This protein enables the following functions: metal ion binding, and DNA-binding transcription factor activity.
MKTTATSFVTGERVVVFVVVSRILLSLPLSLISHGFSLFLLSLSAFLVEIRVETSPFLLSHFSSRRGASSGILLGAVTLPSVMISKLVQLSRAISIHEAEQDELAHVTMQYWAASASCCAILIYLSVIMSQVRKDESLSSSSIWLTRVSLTGTVLYGVACFVSLSMISHTGLNTSLKMLWMLFHGLAAVKLIRHLLCTFPSCASIGEALLVTSGLVLYFGDFLACTIAKIFEKLIPVDLVSISYGIKRTETGIIVQGLLLGLLLFPMVFRFVLHIYESSLRKRDARQRNCSDAAKSVLFFVSLLFFMVVAVPSWMQFVHDFNQHPFLWVLTFVFSEPLKRLSLCIYWILLIVVSVSRFYNISRSSKVERILLRKYYHLMAVLMFLPALVLQPKFLDLAFGAALAVFVALEIIRIWRIQPLGEPLHQFMNAFTDHRDSEHLIVSHFSLLLGCALPIWMSSGFNDRALSPFAGILSLGIGDTMASMVGHKYGVLRWSKTGKKTVEGTAAGITSMMAVCFVLVPILASMGYILSQGWWSLLVAVTATGMLEAYTAQLDNAFIPLVFYSLLCL	This protein is part of the following components: endoplasmic reticulum, integral component of endoplasmic reticulum membrane, integral component of membrane, endoplasmic reticulum membrane, and membrane. This protein is involved in the following processs: pollen tube reception, dolichyl monophosphate biosynthetic process, protein glycosylation, pollen development, and phosphorylation. This protein is active in the following component: integral component of endoplasmic reticulum membrane. This protein is located in the following components: endoplasmic reticulum membrane, membrane, endoplasmic reticulum, and integral component of membrane. This protein is involved in metabolic process: protein glycosylation. This protein is part of membrane: membrane, and endoplasmic reticulum membrane. This protein is part of integral component of membrane: integral component of endoplasmic reticulum membrane, and integral component of membrane. This protein enables transferase activity: transferase activity, dolichol kinase activity, and kinase activity. This protein is involved in lipid metabolic process: dolichyl monophosphate biosynthetic process. This protein is involved in phosphorylation: phosphorylation. This protein enables the following functions: dolichol kinase activity, transferase activity, and kinase activity.
MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTDPASLKSSDTNLFDGNVPSNKSSFSRGDERRHEAAVPPLAVSSTRPEKRESRVSTSSQEQKATNVRQTYDDGAATRLMSTVKPLRELAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKTTVTLTYGSSRPSIEIYRPPATRNTDSGAHLNRLQFQQQQNSIHAAKQLDIQSSRVYETGRLCEPEVLNSLEETYSPFFRSNAEKMSIEEENFRKRKLPVVSSVVKVKKFSHDGEEEEEDDDCGSRTGSISSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVSQKQTLPVAPRTRTSQEDLLAEVAQGHGRVPRISSPVKEEEAQGGSVDERQGTQQRQLLSRLQIDPVMAETLQISQDYYDMESMVHADTRSFILKKPKLCEELVVAASQASGMETADALQARSGHLVQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEDMCSEGMRPAQHPAASHGGLAGLLHPQRSRVLSRQLEDPDGSFANAEMSELSVAQKPEKLLERCKYWPACKNGDECAYHHPVSPCKAFPNCKFAEKCLFVHPNCKYDAKCTKPDCPFTHMSRRTPGLPPKPVTAPAPPSSSQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCAFYHPTITVPPRHALKWIRPQTSD	This protein is part of the following components: nuclear speck, cytoplasm, and nucleus. This protein is involved in the following processs: regulation of mRNA stability, and negative regulation of mRNA polyadenylation. This protein is active in the following components: cytoplasm, and nucleus. This protein is located in the following components: nuclear speck, and nucleus. This protein enables metal ion binding: metal ion binding. This protein enables RNA binding: poly(A) binding, and RNA binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables the following functions: metal ion binding, RNA binding, and poly(A) binding.
MDWKDVLRRRLASPNSDPKRKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQIPPMIGEEAMINYENFLKVGEKAGPKCKQFFTAKVFAKLLHTDSYGRVSIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDNENSADLDDT	This protein is part of the following components: cytosol, spindle, nucleoplasm, nucleus, Golgi apparatus, centrosome, and cytoplasm. This protein is involved in the following processs: regulation of dephosphorylation, activation of protein kinase activity, regulation of B cell activation, regulation of antimicrobial humoral response, B cell homeostasis, spleen development, regulation of mitochondrial depolarization, positive regulation of B cell differentiation, microtubule cytoskeleton organization, cortical cytoskeleton organization, and T cell homeostasis. This protein is active in the following components: centrosome, and spindle. This protein is located in the following components: cytoplasm, cytosol, centrosome, nucleoplasm, nucleus, and Golgi apparatus. This protein enables metal ion binding: metal ion binding. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein enables the following function: metal ion binding.
MENMAEEELLPLEKEEVEVAQVQVPTPARDSAGVPAPAPDSALDSAPTPASAPAPAPALAQAPALSPSLASAPEEAKSKRHISIQRQLADLENLAFVTDGNFDSASSLNSDNLDAGNRQACPLCPKEKFRACNSHKLRRHLQNLHWKVSVEFEGYRMCICHLPCRPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKGETKSSYIAASTAKPPKEILKEADTDVQVCPNYSIPQKTDSYFNPKMKLNRQLIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQENCHLNKLKVVVDSKEKEKSDDILEEGEKNLGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLFESLHHGLDDIQTLIKTLIFESECTPQSQFSIHASSNVNKQEENGVFIKTTDDTTTDNYIAQGKRKSNEMITNLGKKQKTDVSTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLKYSTPTYTGGQSESHVQSASEDTVTERVEMSVNDKAEASGCRRW	This protein is part of the following component: nucleus. This protein is involved in the following processs: tRNA processing, methylation, behavior, and tRNA N2-guanine methylation. This protein is active in the following component: nucleus. This protein enables metal ion binding: metal ion binding. This protein enables RNA binding: tRNA binding, and RNA binding. This protein is part of nucleus: nucleus. This protein enables transferase activity: transferase activity, methyltransferase activity, and tRNA (guanine-N2-)-methyltransferase activity. This protein is involved in methylation: methylation. This protein is not involved in tRNA processing: tRNA processing, and tRNA N2-guanine methylation. This protein enables the following functions: tRNA binding, methyltransferase activity, transferase activity, metal ion binding, protein binding, tRNA (guanine-N2-)-methyltransferase activity, nucleic acid binding, and RNA binding.
MSQSLRIVFAGTPDFAARHLAALLSSEHEIIAVYTQPERPAGRGKKLTASPVKTLALEHNVPVYQPENFKSDESKQQLAALNADLMVVVAYGLLLPKVVLDTPKLGCINVHGSILPRWRGAAPIQRSIWAGDSETGVTIMQMDVGLDTGDMLKIATLPIEASDTSASMYDKLAELGPQALLECLQDIAQGTAVAVKQDDGLANYAHKLSKEEARINWSDAATHIERCIRAFNPWPMSHFEVAENSIKVWQARVETRAVTQTPGTIIQADKSGIYVATGQDVLVLESLQIPGKKALPVQDILNARADWFSVGSQLS	This protein is involved in the following processs: charged-tRNA amino acid modification, conversion of methionyl-tRNA to N-formyl-methionyl-tRNA, translational initiation, translation, and biosynthetic process. This protein is involved in metabolic process: translational initiation, and biosynthetic process. This protein enables catalytic activity: catalytic activity. This protein enables transferase activity: hydroxymethyl-, formyl- and related transferase activity, transferase activity, and methionyl-tRNA formyltransferase activity. This protein is involved in translation: translation. This protein is not involved in tRNA processing: charged-tRNA amino acid modification, and conversion of methionyl-tRNA to N-formyl-methionyl-tRNA. This protein enables the following functions: transferase activity, methionyl-tRNA formyltransferase activity, hydroxymethyl-, formyl- and related transferase activity, and catalytic activity.
MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDSPCLYRPAVLLDGAVYDLSIRDGDVAGPGSSPRSLEEWPDPKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAENRPAGAPEAPILVVGNKRDRQRLRFGPRRALATLVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRTRPAHPTLRLQGALHPARCSLM	This protein is part of the following components: membrane, nucleolus, cellular_component, nucleus, and plasma membrane. This protein is involved in the following processs: biological_process, and signal transduction. This protein acts upstream of or within the following process: biological_process. This protein is active in the following component: cellular_component. This protein is located in the following components: nucleolus, membrane, nucleus, and plasma membrane. This protein enables hydrolase activity: GTPase activity. This protein is involved in signal transduction: signal transduction. This protein enables nucleotide binding: GTP binding, and nucleotide binding. This protein is part of membrane: membrane, and plasma membrane. This protein is part of nucleus: nucleus. This protein enables the following functions: hydrolase activity, GTPase activity, G protein activity, nucleotide binding, and GTP binding.
MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDPDRYICSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI	This protein is part of the following components: endoplasmic reticulum, Golgi membrane, Golgi apparatus, endoplasmic reticulum membrane, membrane, and integral component of membrane. This protein is involved in the following processs: intracellular signal transduction, Notch signaling pathway, amyloid precursor protein catabolic process, proteolysis, mitochondrion-endoplasmic reticulum membrane tethering, regulation of calcium import into the mitochondrion, and protein processing. This protein is located in the following components: endoplasmic reticulum, endoplasmic reticulum membrane, membrane, integral component of membrane, Golgi membrane, and Golgi apparatus. This protein enables hydrolase activity: aspartic endopeptidase activity, intramembrane cleaving, hydrolase activity, aspartic-type endopeptidase activity, and peptidase activity. This protein is involved in signal transduction: intracellular signal transduction, and Notch signaling pathway. This protein is involved in metabolic process: amyloid precursor protein catabolic process. This protein is part of membrane: membrane, Golgi membrane, and endoplasmic reticulum membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in proteolysis: proteolysis, and protein processing. This protein enables the following functions: peptidase activity, aspartic-type endopeptidase activity, aspartic endopeptidase activity, intramembrane cleaving, and hydrolase activity.
MKLDTSGLETTMPVIGFGSNSEMLDGFSSAPSFDLPRTTDFDGFQKKAVEMVKPAKGTTTLAFIFKEGVMVAADSRASMGGYISSQSVKKIIEINPYMLGTMAGGAADCQFWHRNLGIKCRLHELANKRRISVSGASKLLANMLYSYRGMGLSVGTMIAGWDETGPGLYYVDNEGGRLKGDRFSVGSGSPYAYGVLDSGYKFDMSVEEASELARRSIYHATFRDGASGGVASVYHVGPQGWTKLSGDDVGELHYHYYPVAPITAEHVMEEAAE	This protein is part of the following components: cytoplasm, proteasome complex, cytosol, proteasome core complex, nucleus, and proteasome core complex, beta-subunit complex. This protein is involved in the following processs: proteolysis involved in cellular protein catabolic process, proteolysis, proteasome-mediated ubiquitin-dependent protein catabolic process, proteasomal ubiquitin-independent protein catabolic process, and proteasomal protein catabolic process. This protein is active in the following components: cytoplasm, and nucleus. This protein is located in the following components: cytoplasm, nucleus, and cytosol. This protein enables hydrolase activity: endopeptidase activity, hydrolase activity, threonine-type endopeptidase activity, and peptidase activity. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is involved in proteolysis: proteolysis involved in cellular protein catabolic process, proteolysis, proteasomal ubiquitin-independent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, and proteasomal protein catabolic process. This protein is part of cytosol: cytosol. This protein enables the following functions: endopeptidase activity, peptidase activity, hydrolase activity, and threonine-type endopeptidase activity.
MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAELAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLLDAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS	This protein is part of the following components: perinuclear region of cytoplasm, nucleus, cytosol, and protein-containing complex. This protein is involved in the following processs: positive regulation of epithelial cell migration, protein dephosphorylation, positive regulation of stress fiber assembly, cellular response to drug, positive regulation of cell migration, positive regulation of growth, negative regulation of cell-cell adhesion mediated by cadherin, intrinsic apoptotic signaling pathway, peptidyl-serine dephosphorylation, negative regulation of protein kinase activity, positive regulation of focal adhesion assembly, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of cellular protein localization, histone dephosphorylation, negative regulation of protein kinase activity by regulation of protein phosphorylation, positive regulation of gene expression, positive regulation of chemotaxis, negative regulation of protein transport, apoptotic process, positive regulation of cell-substrate adhesion, negative regulation of peptidyl-serine phosphorylation, negative regulation of transcription, DNA-templated, and peptidyl-threonine dephosphorylation. This protein is active in the following components: cytosol, and nucleus. This protein is located in the following components: cytosol, and perinuclear region of cytoplasm. This protein enables hydrolase activity: calmodulin-dependent protein phosphatase activity, protein serine/threonine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity, phosphoprotein phosphatase activity, and hydrolase activity. This protein is involved in signal transduction: intrinsic apoptotic signaling pathway. This protein is involved in metabolic process: protein dephosphorylation, peptidyl-threonine dephosphorylation, histone dephosphorylation, and peptidyl-serine dephosphorylation. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: catalytic activity. This protein is part of nucleus: nucleus. This protein is part of cytosol: cytosol. This protein is involved in regulation of transcription, DNA-templated: negative regulation of transcription, DNA-templated. This protein enables the following functions: protein tyrosine/serine/threonine phosphatase activity, protein binding, protein serine/threonine phosphatase activity, phosphoprotein phosphatase activity, hydrolase activity, cation binding, calmodulin-dependent protein phosphatase activity, protein serine/threonine phosphatase activity, phosphatase activity, protein threonine phosphatase activity, protein serine phosphatase activity, catalytic activity, and metal ion binding.
MASRRGALIVLEGVDRAGKTTQGLKLVTALCASGHRAELLRFPERSTEIGKLLNSYLEKKTELEDHSVHLLFSANRWEQVPLIKAKLNQGVTLVLDRYAFSGVAFTGAKENFSLDWCKQPDVGLPKPDLILFLQLQLLDAAARGEFGLERYETGTFQKQVLLCFQQLMEEKNLNWKVVDASKSIEEVHKEIRAHSEDAIRNAAQRPLGELWK	This protein is part of the following components: cytosol, mitochondrion, mitochondrial intermembrane space, nucleus, mitochondrial matrix, and cytoplasm. This protein is involved in the following processs: dTDP biosynthetic process, response to estrogen, phosphorylation, nucleotide biosynthetic process, response to cadmium ion, myoblast differentiation, dUDP biosynthetic process, dTTP biosynthetic process, nucleoside monophosphate phosphorylation, and nucleoside diphosphate phosphorylation. This protein acts upstream of or within the following processs: cellular response to growth factor stimulus, nucleotide biosynthetic process, dTTP biosynthetic process, and dTDP biosynthetic process. This protein is active in the following components: cytosol, nucleus, mitochondrion, and cytoplasm. This protein is located in the following components: mitochondrion, mitochondrial intermembrane space, and mitochondrial matrix. This protein is involved in metabolic process: nucleoside monophosphate phosphorylation, dUDP biosynthetic process, dTTP biosynthetic process, dTDP biosynthetic process, and nucleotide biosynthetic process. This protein enables nucleotide binding: nucleotide binding, and ATP binding. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein enables transferase activity: thymidylate kinase activity, nucleoside diphosphate kinase activity, uridylate kinase activity, kinase activity, and transferase activity. This protein is part of cytosol: cytosol. This protein is involved in phosphorylation: nucleoside diphosphate phosphorylation, and phosphorylation. This protein enables the following functions: nucleotide binding, uridylate kinase activity, transferase activity, kinase activity, thymidylate kinase activity, ATP binding, and nucleoside diphosphate kinase activity.
MLLILLSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGSPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ	This protein is part of the following component: extracellular region. This protein is involved in the following processs: defense response to Gram-negative bacterium, and biological_process. This protein is located in the following component: extracellular region. This protein is part of extracellular region: extracellular region. This protein enables the following function: protein binding.
MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA	This protein is part of the following components: endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum, COPI-coated vesicle membrane, Golgi apparatus, endoplasmic reticulum membrane, cytoplasmic vesicle, integral component of membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, membrane, Golgi membrane, and cis-Golgi network. This protein is involved in the following processs: protein retention in ER lumen, retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, protein transport, vesicle-mediated transport, and endoplasmic reticulum to Golgi vesicle-mediated transport. This protein acts upstream of or within the following processs: T cell differentiation, T cell cytokine production, retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, and T cell apoptotic process. This protein colocalizes with the following component: COPI-coated vesicle membrane. This protein is active in the following components: cis-Golgi network, and endoplasmic reticulum. This protein is located in the following components: integral component of membrane, endoplasmic reticulum, COPI-coated vesicle membrane, cytoplasmic vesicle, Golgi apparatus, membrane, Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi network. This protein is involved in metabolic process: T cell cytokine production. This protein is part of membrane: membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi membrane, endoplasmic reticulum membrane, and COPI-coated vesicle membrane. This protein is part of integral component of membrane: integral component of membrane. This protein is involved in protein transport: protein transport. This protein enables the following functions: ER retention sequence binding, and KDEL sequence binding.
MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK	This protein is part of the following components: phosphatidylinositol 3-kinase complex, class III, type I, Golgi apparatus, phosphatidylinositol 3-kinase complex, class III, type II, endosome membrane, endoplasmic reticulum membrane, endosome, mitochondrial membrane, mitochondrion, cytosol, extrinsic component of membrane, cytoplasmic vesicle, nucleus, phosphatidylinositol 3-kinase complex, class III, cytoplasm, phagophore assembly site, membrane, endoplasmic reticulum, protein-containing complex, and autophagosome. This protein is involved in the following processs: mitotic metaphase plate congression, cell cycle, cellular response to epidermal growth factor stimulus, apoptotic process, amyloid-beta metabolic process, aging, cell division, cellular defense response, positive regulation of phosphatidylinositol 3-kinase signaling, early endosome to late endosome transport, autophagosome assembly, cellular response to glucose starvation, negative regulation of reactive oxygen species metabolic process, receptor catabolic process, regulation of cytokinesis, cellular response to aluminum ion, autophagy, response to nutrient levels, negative regulation of cell population proliferation, positive regulation of autophagosome assembly, response to mitochondrial depolarisation, negative regulation of apoptotic process, neuron development, macroautophagy, positive regulation of intrinsic apoptotic signaling pathway, defense response to virus, endocytosis, cellular response to copper ion, lysosome organization, engulfment of apoptotic cell, mitophagy, cellular response to amino acid starvation, response to hypoxia, response to iron(II) ion, cellular response to hydrogen peroxide, negative regulation of lysosome organization, negative regulation of autophagosome assembly, autophagy of mitochondrion, positive regulation of cardiac muscle hypertrophy, late endosome to vacuole transport, response to drug, negative regulation of cell death, response to lead ion, response to other organism, positive regulation of autophagy, regulation of catalytic activity, response to vitamin E, cellular response to nitrogen starvation, positive regulation of attachment of mitotic spindle microtubules to kinetochore, negative regulation of autophagy, protein deubiquitination, and viral process. This protein colocalizes with the following component: mitochondrion. This protein is active in the following component: phagophore assembly site. This protein is located in the following components: trans-Golgi network, endosome, autophagosome, mitochondrion, membrane, dendrite, endoplasmic reticulum, nucleus, phagocytic vesicle, extrinsic component of membrane, cytoplasm, mitochondrial membrane, cytoplasmic vesicle, cytosol, Golgi apparatus, endoplasmic reticulum membrane, and endosome membrane. This protein is involved in metabolic process: receptor catabolic process, autophagy of mitochondrion, mitophagy, macroautophagy, and autophagy. This protein is part of membrane: membrane, endoplasmic reticulum membrane, mitochondrial membrane, and endosome membrane. This protein is part of mitochondrion: mitochondrion. This protein is part of cytoplasm: cytoplasm. This protein is part of nucleus: nucleus. This protein is involved in proteolysis: protein deubiquitination. This protein is part of cytosol: cytosol. This protein is involved in cell cycle: cell cycle. This protein is involved in cell division: cell division. This protein enables the following functions: ubiquitin protein ligase binding, protein kinase binding, phosphatidylinositol 3-kinase binding, GTPase binding, identical protein binding, and protein binding.
MNWLEERMPGIGRIAKDIAEHPVPSHTLNIFYCLGGLTLLCFIIQCLTGVFLAFYYKPTPEAAFASVQMITNEVRFGSVIRSMHHWSCQLMILLVFLHMLRVYYTGAFKKPRELNWVAGCFLLVLSLGLAFTGYLLPYEQLSYWASVIGAETANTLPVIGPTLKIMMQGGIKVTAEMLSRFYVLHVMILPAITIGFLVAHFIMIRVQGISDPM	This protein is part of the following components: integral component of membrane, plasma membrane, and membrane. This protein is involved in the following processs: photosynthesis, and respiratory electron transport chain. This protein is located in the following components: plasma membrane, integral component of membrane, and membrane. This protein is involved in metabolic process: photosynthesis, and respiratory electron transport chain. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: electron transfer activity, oxidoreductase activity, and electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity. This protein is part of membrane: membrane, and plasma membrane. This protein is part of integral component of membrane: integral component of membrane. This protein enables the following functions: electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity, electron transfer activity, metal ion binding, and oxidoreductase activity.
MSTRSKSVPVPAGGGAATVPLAVLLRREVVSEKTAAERPELQVGLFSQAKKGEDYTFLKPDCERLPGVPSSSFSAFGLFDGHNGNGAAIYTKENLLSNILTAIPADLNREDWLAALPRAMVAAFVKTDKDFQTKARSSGTTVTFVIIDGLFITVASVGDSRCVLEAEGSIYHLSADHRFDASKEEVDRVTESGGDVGRLNVVGGAEIGPLRCWPGGLCLSRSIGDQDVGQFIVPVPYVKQVKLSTAGGRLIISSDGVWDVLTAEVAFNCSRTLPPEAAAEQIVKEAVQQKGLRDDTTCIVVDILPDKANLTMPHTKKQPGMGVFKNMFRKKTPSDSSSHTDREYMDPDIVEEIFEDGCAFLSKRLDSEYPVRNMFKLFICAICQVELKPSQGISVHEDSSQPGNLRRWDGPFLCQGCQEKKEAMEGKRRSRDSSSRNSGSSE	This protein is involved in the following processs: protein dephosphorylation, and dephosphorylation. This protein enables hydrolase activity: hydrolase activity, protein serine/threonine phosphatase activity, and phosphoprotein phosphatase activity. This protein is involved in metabolic process: protein dephosphorylation. This protein enables metal ion binding: metal ion binding. This protein enables catalytic activity: catalytic activity. This protein enables the following functions: protein serine/threonine phosphatase activity, protein serine phosphatase activity, hydrolase activity, catalytic activity, protein threonine phosphatase activity, phosphoprotein phosphatase activity, metal ion binding, phosphatase activity, and protein serine/threonine phosphatase activity.