| Target-AMP Designer is a protein-language-model-based framework for controllable therapeutic peptide generation and screening. It is designed to generate peptide candidates with specific therapeutic functions while modulating key physicochemical properties such as solubility and stability. The framework integrates functional prompts, continuous attribute conditioning, target-associated structure prediction, docking-based screening, Rosetta refinement, and molecular dynamics validation into a unified computational workflow. By combining sequence-level controllable generation with structure-aware candidate prioritization, Target-AMP Designer provides an extensible platform for AI-assisted therapeutic peptide design and in silico screening. |
