| cases: |
| - case_id: SFB_FS_A1AT_1QLPA_1OPHA |
| pattern: fold_switch_metamorphic |
| query_uniprot: P01009 |
| query_pdb: 1QLP |
| query_chain: A |
| query_resi_range: 23..394 |
| query_length: 372 |
| state_a_pdb: 1QLP |
| state_a_chain: A |
| state_b_pdb: 1OPH |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Alpha-1 antitrypsin native serpin <-> cleaved/latent |
| metastable conformation |
| literature_ref: Elliott 1996 Nat Struct Biol |
| source: https://doi.org/10.1038/nsb1196-910 |
| notes: '' |
| qc: |
| n_common_residues: 372 |
| n_common_core_lt3A: 359 |
| n_switch_region_ge3A: 13 |
| core_fraction: 0.965 |
| - case_id: SFB_FS_CLIC1_1K0MA_1K0NA |
| pattern: fold_switch_metamorphic |
| query_uniprot: O00299 |
| query_pdb: 1K0M |
| query_chain: A |
| query_resi_range: 6..240 |
| query_length: 235 |
| state_a_pdb: 1K0M |
| state_a_chain: A |
| state_b_pdb: 1K0N |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: CLIC1 soluble GST-fold <-> membrane chloride-channel |
| conformation |
| literature_ref: Littler 2004 J Biol Chem |
| source: https://doi.org/10.1074/jbc.M308444200 |
| notes: '' |
| qc: |
| n_common_residues: 225 |
| n_common_core_lt3A: 220 |
| n_switch_region_ge3A: 5 |
| core_fraction: 0.978 |
| - case_id: SFB_FS_DLC8_2PG1A_1F3CA |
| pattern: fold_switch_metamorphic |
| query_uniprot: P63167 |
| query_pdb: 2PG1 |
| query_chain: A |
| query_resi_range: 5..89 |
| query_length: 85 |
| state_a_pdb: 2PG1 |
| state_a_chain: A |
| state_b_pdb: 1F3C |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: DLC8/LC8 dynein light chain dimerization-coupled fold |
| switch |
| literature_ref: Fan 2001 JMB |
| source: https://doi.org/10.1006/jmbi.2001.4953 |
| notes: '' |
| qc: |
| n_common_residues: 85 |
| n_common_core_lt3A: 83 |
| n_switch_region_ge3A: 2 |
| core_fraction: 0.976 |
| - case_id: SFB_FS_GA98GB98_2LHCA_2LHDA |
| pattern: fold_switch_metamorphic |
| query_uniprot: '' |
| query_pdb: 2LHC |
| query_chain: A |
| query_resi_range: 1..56 |
| query_length: 56 |
| state_a_pdb: 2LHC |
| state_a_chain: A |
| state_b_pdb: 2LHD |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: 'GA98/GB98 engineered fold-switch: 3-alpha (GA) <-> |
| 4-beta+alpha (GB)' |
| literature_ref: Alexander 2009 PNAS |
| source: https://doi.org/10.1073/pnas.0905068106 |
| notes: '' |
| qc: |
| n_common_residues: 56 |
| n_common_core_lt3A: 10 |
| n_switch_region_ge3A: 46 |
| core_fraction: 0.179 |
| - case_id: SFB_FS_IscU_1WFZA_2KQKA |
| pattern: fold_switch_metamorphic |
| query_uniprot: P0ACD4 |
| query_pdb: 1WFZ |
| query_chain: A |
| query_resi_range: 1..130 |
| query_length: 130 |
| state_a_pdb: 1WFZ |
| state_a_chain: A |
| state_b_pdb: 2KQK |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: IscU disordered (D) <-> structured (S) Fe-S cluster |
| scaffold |
| literature_ref: Kim 2012 PNAS |
| source: https://doi.org/10.1073/pnas.1212358109 |
| notes: '' |
| qc: |
| n_common_residues: 128 |
| n_common_core_lt3A: 30 |
| n_switch_region_ge3A: 98 |
| core_fraction: 0.234 |
| - case_id: SFB_FS_KAIA_1R8JA_1R8QA |
| pattern: fold_switch_metamorphic |
| query_uniprot: Q79V62 |
| query_pdb: 1R8J |
| query_chain: A |
| query_resi_range: 1..282 |
| query_length: 272 |
| state_a_pdb: 1R8J |
| state_a_chain: A |
| state_b_pdb: 1R8Q |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: KaiA C-terminal domain conformational reshuffling |
| literature_ref: Ye 2004 PNAS |
| source: https://doi.org/10.1073/pnas.0405842101 |
| notes: '' |
| qc: |
| n_common_residues: 169 |
| n_common_core_lt3A: 3 |
| n_switch_region_ge3A: 166 |
| core_fraction: 0.018 |
| - case_id: SFB_FS_KAIB_2QKEB_5JYTA |
| pattern: fold_switch_metamorphic |
| query_uniprot: Q79V61 |
| query_pdb: 2QKE |
| query_chain: B |
| query_resi_range: 5..95 |
| query_length: 91 |
| state_a_pdb: 2QKE |
| state_a_chain: B |
| state_b_pdb: 5JYT |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Thioredoxin-fold <-> KaiB-fold metamorphic switch (circadian |
| clock B-subunit) |
| literature_ref: Chang 2015 Science; Murzin 2008 Science |
| source: https://doi.org/10.1126/science.aaa1374 |
| notes: Reference metamorphic case from AF-Cluster paper |
| qc: |
| n_common_residues: 91 |
| n_common_core_lt3A: 44 |
| n_switch_region_ge3A: 47 |
| core_fraction: 0.484 |
| - case_id: SFB_FS_MAD2_1DUJA_1GO4A |
| pattern: fold_switch_metamorphic |
| query_uniprot: Q13257 |
| query_pdb: 1DUJ |
| query_chain: A |
| query_resi_range: 11..197 |
| query_length: 187 |
| state_a_pdb: 1DUJ |
| state_a_chain: A |
| state_b_pdb: 1GO4 |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: MAD2 O-MAD2 (open) <-> C-MAD2 (closed) spindle-checkpoint |
| metamorphic |
| literature_ref: Luo 2004 Nat Struct Mol Biol |
| source: https://doi.org/10.1038/nsmb748 |
| notes: '' |
| qc: |
| n_common_residues: 187 |
| n_common_core_lt3A: 9 |
| n_switch_region_ge3A: 178 |
| core_fraction: 0.048 |
| - case_id: SFB_FS_MPT53_1LU4A_3EMXA |
| pattern: fold_switch_metamorphic |
| query_uniprot: P9WG70 |
| query_pdb: 1LU4 |
| query_chain: A |
| query_resi_range: 1001..1134 |
| query_length: 134 |
| state_a_pdb: 1LU4 |
| state_a_chain: A |
| state_b_pdb: 3EMX |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: 'Mpt53 secreted disulfide-isomerase: alternate fold |
| candidate (DALI hit 3EMX, Aeropyrum pernix thioredoxin)' |
| literature_ref: Goulding 2004 J Mol Biol |
| source: https://doi.org/10.1016/j.jmb.2004.05.060 |
| notes: Pair-aligned by positional CA index because 1LU4 (1001..1134) and 3EMX (224..347) |
| share no residue numbers. 3EMX is a DALI hit only; biological metamorphism not |
| proven. |
| qc: |
| n_common_residues: 124 |
| n_common_core_lt3A: 1 |
| n_switch_region_ge3A: 123 |
| core_fraction: 0.008 |
| - case_id: SFB_FS_NTRC2_1NY3A_3DZEA |
| pattern: fold_switch_metamorphic |
| query_uniprot: P0AFB8 |
| query_pdb: 1NY3 |
| query_chain: A |
| query_resi_range: 46..345 |
| query_length: 277 |
| state_a_pdb: 1NY3 |
| state_a_chain: A |
| state_b_pdb: 3DZE |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: NtrC receiver domain inactive <-> active fold-switch-like |
| rearrangement |
| literature_ref: Hastings 2008 PNAS |
| source: https://doi.org/10.1073/pnas.0709728105 |
| notes: '' |
| qc: |
| n_common_residues: 124 |
| n_common_core_lt3A: 1 |
| n_switch_region_ge3A: 123 |
| core_fraction: 0.008 |
| - case_id: SFB_FS_NUSG_2K06A_2LQ8A |
| pattern: fold_switch_metamorphic |
| query_uniprot: P0AFG0 |
| query_pdb: 2K06 |
| query_chain: A |
| query_resi_range: 1..123 |
| query_length: 123 |
| state_a_pdb: 2K06 |
| state_a_chain: A |
| state_b_pdb: 2LQ8 |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: 'NusG-SP CTD: KOW-fold <-> alpha-hairpin metamorphic' |
| literature_ref: Burmann 2010 Science |
| source: https://doi.org/10.1126/science.1184953 |
| notes: '' |
| qc: |
| n_common_residues: 123 |
| n_common_core_lt3A: 2 |
| n_switch_region_ge3A: 121 |
| core_fraction: 0.016 |
| - case_id: SFB_FS_P13_2I4ZA_4M1EA |
| pattern: fold_switch_metamorphic |
| query_uniprot: Q98DV5 |
| query_pdb: 2I4Z |
| query_chain: A |
| query_resi_range: 207..476 |
| query_length: 270 |
| state_a_pdb: 2I4Z |
| state_a_chain: A |
| state_b_pdb: 4M1E |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: p13 metamorphic protein (intracellular signaling) |
| literature_ref: Roessler 2015 JMB |
| source: https://doi.org/10.1016/j.jmb.2014.10.010 |
| notes: '' |
| qc: |
| n_common_residues: 67 |
| n_common_core_lt3A: 3 |
| n_switch_region_ge3A: 64 |
| core_fraction: 0.045 |
| - case_id: SFB_FS_RFAH_5ONDA_6C6SD |
| pattern: fold_switch_metamorphic |
| query_uniprot: P0AFW0 |
| query_pdb: 5OND |
| query_chain: A |
| query_resi_range: 1..155 |
| query_length: 135 |
| state_a_pdb: 5OND |
| state_a_chain: A |
| state_b_pdb: 6C6S |
| state_b_chain: D |
| target_state: B |
| expected_pattern_signature: 'RfaH CTD: alpha-helical hairpin <-> beta-barrel (transcription/translation |
| coupling)' |
| literature_ref: Burmann 2012 Cell; Zuber 2018 Nat Commun |
| source: https://doi.org/10.1038/s41467-019-10918-2 |
| notes: '' |
| qc: |
| n_common_residues: 134 |
| n_common_core_lt3A: 79 |
| n_switch_region_ge3A: 55 |
| core_fraction: 0.59 |
| - case_id: SFB_FS_SELECASE_4QHFA_4QHGA |
| pattern: fold_switch_metamorphic |
| query_uniprot: I3VWL5 |
| query_pdb: 4QHF |
| query_chain: A |
| query_resi_range: 1..109 |
| query_length: 109 |
| state_a_pdb: 4QHF |
| state_a_chain: A |
| state_b_pdb: 4QHG |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Selecase oligomer monomer fold switch (zinc metallopeptidase) |
| literature_ref: Lopez-Pelegrin 2014 Cell Rep |
| source: https://doi.org/10.1016/j.celrep.2014.06.012 |
| notes: '' |
| qc: |
| n_common_residues: 107 |
| n_common_core_lt3A: 99 |
| n_switch_region_ge3A: 8 |
| core_fraction: 0.925 |
| - case_id: SFB_FS_XCL1_1J8IA_2JP1A |
| pattern: fold_switch_metamorphic |
| query_uniprot: P47992 |
| query_pdb: 1J8I |
| query_chain: A |
| query_resi_range: 1..93 |
| query_length: 93 |
| state_a_pdb: 1J8I |
| state_a_chain: A |
| state_b_pdb: 2JP1 |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: 'Lymphotactin: chemokine-fold <-> all-beta dimer fold |
| metamorphic switch' |
| literature_ref: Tuinstra 2008 PNAS |
| source: https://doi.org/10.1073/pnas.0711389105 |
| notes: '' |
| qc: |
| n_common_residues: 60 |
| n_common_core_lt3A: 20 |
| n_switch_region_ge3A: 40 |
| core_fraction: 0.333 |
| - case_id: SFB_AL_AKE_4AKEA_1AKEA |
| pattern: allosteric_ligand_induced |
| query_uniprot: P69441 |
| query_pdb: 4AKE |
| query_chain: A |
| query_resi_range: 1..214 |
| query_length: 214 |
| state_a_pdb: 4AKE |
| state_a_chain: A |
| state_b_pdb: 1AKE |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Adenylate kinase open (apo) <-> closed (Ap5A-bound) |
| lid-rearrangement |
| literature_ref: Muller 1992 JMB; Henzler-Wildman 2007 Nature |
| source: https://doi.org/10.1038/nature06407 |
| notes: '' |
| qc: |
| n_common_residues: 214 |
| n_common_core_lt3A: 126 |
| n_switch_region_ge3A: 88 |
| core_fraction: 0.589 |
| - case_id: SFB_AL_CALM_1CFDA_1CLLA |
| pattern: allosteric_ligand_induced |
| query_uniprot: P0DP23 |
| query_pdb: 1CFD |
| query_chain: A |
| query_resi_range: 1..148 |
| query_length: 148 |
| state_a_pdb: 1CFD |
| state_a_chain: A |
| state_b_pdb: 1CLL |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Calmodulin apo (collapsed) <-> Ca2+-bound (extended) |
| conformational switch |
| literature_ref: Kuboniwa 1995 Nat Struct Biol |
| source: https://doi.org/10.1038/nsb0995-768 |
| notes: '' |
| qc: |
| n_common_residues: 144 |
| n_common_core_lt3A: 21 |
| n_switch_region_ge3A: 123 |
| core_fraction: 0.146 |
| - case_id: SFB_AL_CDK6_1BI7A_2EUFB |
| pattern: allosteric_ligand_induced |
| query_uniprot: Q00534 |
| query_pdb: 1BI7 |
| query_chain: A |
| query_resi_range: 10..301 |
| query_length: 269 |
| state_a_pdb: 1BI7 |
| state_a_chain: A |
| state_b_pdb: 2EUF |
| state_b_chain: B |
| target_state: B |
| expected_pattern_signature: CDK6 kinase inactive (p16-bound) <-> active (V-cyclin) |
| literature_ref: Russo 1998 Nat Struct Biol |
| source: https://doi.org/10.1038/sb0498-262 |
| notes: '' |
| qc: |
| n_common_residues: 255 |
| n_common_core_lt3A: 180 |
| n_switch_region_ge3A: 75 |
| core_fraction: 0.706 |
| - case_id: SFB_AL_CHEY_3CHYA_1FQWA |
| pattern: allosteric_ligand_induced |
| query_uniprot: P0AE67 |
| query_pdb: 3CHY |
| query_chain: A |
| query_resi_range: 2..129 |
| query_length: 128 |
| state_a_pdb: 3CHY |
| state_a_chain: A |
| state_b_pdb: 1FQW |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: CheY response regulator inactive <-> active (Mg-BeF3 |
| phosphorylated) |
| literature_ref: Lee 2001 Nat Struct Biol |
| source: https://doi.org/10.1038/85661 |
| notes: '' |
| qc: |
| n_common_residues: 128 |
| n_common_core_lt3A: 127 |
| n_switch_region_ge3A: 1 |
| core_fraction: 0.992 |
| - case_id: SFB_AL_DHFR_1RX1A_1RX4A |
| pattern: allosteric_ligand_induced |
| query_uniprot: P0ABQ4 |
| query_pdb: 1RX1 |
| query_chain: A |
| query_resi_range: 1..159 |
| query_length: 159 |
| state_a_pdb: 1RX1 |
| state_a_chain: A |
| state_b_pdb: 1RX4 |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: DHFR Met20 loop closed <-> occluded (folate/NADP intermediate) |
| literature_ref: Sawaya 1997 Biochemistry |
| source: https://doi.org/10.1021/bi962337c |
| notes: '' |
| qc: |
| n_common_residues: 159 |
| n_common_core_lt3A: 156 |
| n_switch_region_ge3A: 3 |
| core_fraction: 0.981 |
| - case_id: SFB_AL_EGFR_2GS2A_1XKKA |
| pattern: allosteric_ligand_induced |
| query_uniprot: P00533 |
| query_pdb: 2GS2 |
| query_chain: A |
| query_resi_range: 672..994 |
| query_length: 305 |
| state_a_pdb: 2GS2 |
| state_a_chain: A |
| state_b_pdb: 1XKK |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: EGFR kinase inactive (lapatinib) <-> active asymmetric |
| dimer |
| literature_ref: Wood 2004 Cancer Res |
| source: https://doi.org/10.1158/0008-5472.CAN-04-1168 |
| notes: '' |
| qc: |
| n_common_residues: 252 |
| n_common_core_lt3A: 2 |
| n_switch_region_ge3A: 250 |
| core_fraction: 0.008 |
| - case_id: SFB_AL_GLNBP_1GGGA_1WDNA |
| pattern: allosteric_ligand_induced |
| query_uniprot: P0AEQ3 |
| query_pdb: 1GGG |
| query_chain: A |
| query_resi_range: 5..224 |
| query_length: 220 |
| state_a_pdb: 1GGG |
| state_a_chain: A |
| state_b_pdb: 1WDN |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Glutamine-binding protein open (apo) <-> closed (Gln-bound) |
| literature_ref: Hsiao 1996 JMB |
| source: https://doi.org/10.1006/jmbi.1996.0438 |
| notes: '' |
| qc: |
| n_common_residues: 220 |
| n_common_core_lt3A: 131 |
| n_switch_region_ge3A: 89 |
| core_fraction: 0.595 |
| - case_id: SFB_AL_LIVBP_2LIVA_1Z15A |
| pattern: allosteric_ligand_induced |
| query_uniprot: P0AD96 |
| query_pdb: 2LIV |
| query_chain: A |
| query_resi_range: 1..344 |
| query_length: 344 |
| state_a_pdb: 2LIV |
| state_a_chain: A |
| state_b_pdb: 1Z15 |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Leucine/Ile/Val-BP open (apo) <-> closed (Leu-bound) |
| hinge motion |
| literature_ref: Sack 1989 JMB |
| source: https://doi.org/10.1016/0022-2836(89)90342-6 |
| notes: '' |
| qc: |
| n_common_residues: 344 |
| n_common_core_lt3A: 341 |
| n_switch_region_ge3A: 3 |
| core_fraction: 0.991 |
| - case_id: SFB_AL_MBP_1OMPA_1ANFA |
| pattern: allosteric_ligand_induced |
| query_uniprot: P0AEX9 |
| query_pdb: 1OMP |
| query_chain: A |
| query_resi_range: 1..370 |
| query_length: 370 |
| state_a_pdb: 1OMP |
| state_a_chain: A |
| state_b_pdb: 1ANF |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Maltose-binding protein open (apo) <-> closed (maltose-bound) |
| literature_ref: Sharff 1992 Biochemistry |
| source: https://doi.org/10.1021/bi00163a008 |
| notes: '' |
| qc: |
| n_common_residues: 370 |
| n_common_core_lt3A: 223 |
| n_switch_region_ge3A: 147 |
| core_fraction: 0.603 |
| - case_id: SFB_AL_MEK1_3EQIA_3MBLA |
| pattern: allosteric_ligand_induced |
| query_uniprot: Q02750 |
| query_pdb: 3EQI |
| query_chain: A |
| query_resi_range: 39..382 |
| query_length: 315 |
| state_a_pdb: 3EQI |
| state_a_chain: A |
| state_b_pdb: 3MBL |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: MEK1 inactive (apo) <-> active (ATP/Mg-bound) DFG flip |
| literature_ref: Fischmann 2009 Biochemistry |
| source: https://doi.org/10.1021/bi900132f |
| notes: '' |
| qc: |
| n_common_residues: 290 |
| n_common_core_lt3A: 281 |
| n_switch_region_ge3A: 9 |
| core_fraction: 0.969 |
| - case_id: SFB_AL_PHOB_1B00A_1ZESA |
| pattern: allosteric_ligand_induced |
| query_uniprot: P0AFJ5 |
| query_pdb: 1B00 |
| query_chain: A |
| query_resi_range: 2..123 |
| query_length: 122 |
| state_a_pdb: 1B00 |
| state_a_chain: A |
| state_b_pdb: 1ZES |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: PhoB response-regulator inactive <-> active (BeF3) |
| literature_ref: Bachhawat 2005 Structure |
| source: https://doi.org/10.1016/j.str.2005.04.016 |
| notes: '' |
| qc: |
| n_common_residues: 121 |
| n_common_core_lt3A: 108 |
| n_switch_region_ge3A: 13 |
| core_fraction: 0.893 |
| - case_id: SFB_AL_PKA_1ATPE_2CPKE |
| pattern: allosteric_ligand_induced |
| query_uniprot: P00517 |
| query_pdb: 1ATP |
| query_chain: E |
| query_resi_range: 15..350 |
| query_length: 334 |
| state_a_pdb: 1ATP |
| state_a_chain: E |
| state_b_pdb: 2CPK |
| state_b_chain: E |
| target_state: B |
| expected_pattern_signature: PKA catalytic subunit closed (Mg-ATP-PKI) <-> open (apo) |
| literature_ref: Knighton 1991 Science |
| source: https://doi.org/10.1126/science.1862342 |
| notes: '' |
| qc: |
| n_common_residues: 333 |
| n_common_core_lt3A: 333 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_AL_RAS_4Q21A_5P21A |
| pattern: allosteric_ligand_induced |
| query_uniprot: P01112 |
| query_pdb: 4Q21 |
| query_chain: A |
| query_resi_range: 1..169 |
| query_length: 169 |
| state_a_pdb: 4Q21 |
| state_a_chain: A |
| state_b_pdb: 5P21 |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: H-Ras GDP-bound (inactive) <-> GTP-analog (active) Switch |
| I/II |
| literature_ref: Milburn 1990 Science |
| source: https://doi.org/10.1126/science.2406906 |
| notes: '' |
| qc: |
| n_common_residues: 166 |
| n_common_core_lt3A: 156 |
| n_switch_region_ge3A: 10 |
| core_fraction: 0.94 |
| - case_id: SFB_AL_RBP_1URPA_2DRIA |
| pattern: allosteric_ligand_induced |
| query_uniprot: P02925 |
| query_pdb: 1URP |
| query_chain: A |
| query_resi_range: 1..271 |
| query_length: 271 |
| state_a_pdb: 1URP |
| state_a_chain: A |
| state_b_pdb: 2DRI |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Ribose-binding protein open <-> closed sugar-induced |
| lid closure |
| literature_ref: Bjorkman 1994 JMB |
| source: https://doi.org/10.1006/jmbi.1994.1633 |
| notes: '' |
| qc: |
| n_common_residues: 271 |
| n_common_core_lt3A: 154 |
| n_switch_region_ge3A: 117 |
| core_fraction: 0.568 |
| - case_id: SFB_AL_SRC_2SRCA_1Y57A |
| pattern: allosteric_ligand_induced |
| query_uniprot: P12931 |
| query_pdb: 2SRC |
| query_chain: A |
| query_resi_range: 84..533 |
| query_length: 449 |
| state_a_pdb: 2SRC |
| state_a_chain: A |
| state_b_pdb: 1Y57 |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Src kinase autoinhibited (closed) <-> active (open) |
| C-helix |
| literature_ref: Cowan-Jacob 2005 Structure |
| source: https://doi.org/10.1016/j.str.2005.04.013 |
| notes: '' |
| qc: |
| n_common_residues: 449 |
| n_common_core_lt3A: 12 |
| n_switch_region_ge3A: 437 |
| core_fraction: 0.027 |
| - case_id: SFB_ID_ASYN_1XQ8A_1XQ8A |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P37840 |
| query_pdb: 1XQ8 |
| query_chain: A |
| query_resi_range: 1..140 |
| query_length: 140 |
| state_a_pdb: 1XQ8 |
| state_a_chain: A |
| state_b_pdb: 1XQ8 |
| state_b_chain: A |
| target_state: A |
| expected_pattern_signature: Alpha-synuclein disordered <-> lipid-bound helical conformation |
| literature_ref: Ulmer 2005 JBC |
| source: https://doi.org/10.1074/jbc.M411805200 |
| notes: '' |
| qc: |
| n_common_residues: 140 |
| n_common_core_lt3A: 140 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_BAD_1G5JB_1G5JB |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: Q92934 |
| query_pdb: 1G5J |
| query_chain: B |
| query_resi_range: 301..325 |
| query_length: 25 |
| state_a_pdb: 1G5J |
| state_a_chain: B |
| state_b_pdb: 1G5J |
| state_b_chain: B |
| target_state: A |
| expected_pattern_signature: BAD BH3 IDR disorder-to-order on Bcl-xL binding |
| literature_ref: Petros 2000 PNAS |
| source: https://doi.org/10.1073/pnas.97.7.3012 |
| notes: '' |
| qc: |
| n_common_residues: 25 |
| n_common_core_lt3A: 25 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_BID_1DDBA_1DDBA |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P55957 |
| query_pdb: 1DDB |
| query_chain: A |
| query_resi_range: 1..195 |
| query_length: 195 |
| state_a_pdb: 1DDB |
| state_a_chain: A |
| state_b_pdb: 1DDB |
| state_b_chain: A |
| target_state: A |
| expected_pattern_signature: Bid alpha-helical bundle; BH3 region disordered-to-ordered |
| upon Bcl-xL binding |
| literature_ref: Chou 1999 Cell |
| source: https://doi.org/10.1016/S0092-8674(00)80572-3 |
| notes: '' |
| qc: |
| n_common_residues: 195 |
| n_common_core_lt3A: 195 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_CJUN_1JNMB_1JNMB |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P05412 |
| query_pdb: 1JNM |
| query_chain: B |
| query_resi_range: 254..310 |
| query_length: 57 |
| state_a_pdb: 1JNM |
| state_a_chain: B |
| state_b_pdb: 1JNM |
| state_b_chain: B |
| target_state: A |
| expected_pattern_signature: c-Jun bZIP disorder-to-order coiled coil upon DNA binding/dimerization |
| literature_ref: Glover 1995 Nature |
| source: https://doi.org/10.1038/373257a0 |
| notes: '' |
| qc: |
| n_common_residues: 57 |
| n_common_core_lt3A: 57 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_CREB_1KDXB_1KDXB |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P16220 |
| query_pdb: 1KDX |
| query_chain: B |
| query_resi_range: 119..146 |
| query_length: 27 |
| state_a_pdb: 1KDX |
| state_a_chain: B |
| state_b_pdb: 1KDX |
| state_b_chain: B |
| target_state: A |
| expected_pattern_signature: CREB pKID alpha-helical disorder-to-order on KIX of |
| CBP |
| literature_ref: Radhakrishnan 1997 Cell |
| source: https://doi.org/10.1016/S0092-8674(00)80463-8 |
| notes: '' |
| qc: |
| n_common_residues: 27 |
| n_common_core_lt3A: 27 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_EIF4E_1WKWB_1WKWB |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: Q13541 |
| query_pdb: 1WKW |
| query_chain: B |
| query_resi_range: 47..66 |
| query_length: 20 |
| state_a_pdb: 1WKW |
| state_a_chain: B |
| state_b_pdb: 1WKW |
| state_b_chain: B |
| target_state: A |
| expected_pattern_signature: 4E-BP1 IDR ordered alpha-helix when bound eIF4E |
| literature_ref: Marcotrigiano 1999 Mol Cell |
| source: https://doi.org/10.1016/S1097-2765(00)80194-6 |
| notes: '' |
| qc: |
| n_common_residues: 20 |
| n_common_core_lt3A: 20 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_HIF1A_1L8CB_1L8CB |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: Q16665 |
| query_pdb: 1L8C |
| query_chain: B |
| query_resi_range: 99..149 |
| query_length: 51 |
| state_a_pdb: 1L8C |
| state_a_chain: B |
| state_b_pdb: 1L8C |
| state_b_chain: B |
| target_state: A |
| expected_pattern_signature: HIF-1alpha CTAD disorder-to-order helix on CBP TAZ1 |
| binding |
| literature_ref: Dames 2002 PNAS |
| source: https://doi.org/10.1073/pnas.082121399 |
| notes: '' |
| qc: |
| n_common_residues: 51 |
| n_common_core_lt3A: 51 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_HISTH1_1GHCA_1GHCA |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P10412 |
| query_pdb: 1GHC |
| query_chain: A |
| query_resi_range: 1..75 |
| query_length: 75 |
| state_a_pdb: 1GHC |
| state_a_chain: A |
| state_b_pdb: 1GHC |
| state_b_chain: A |
| target_state: A |
| expected_pattern_signature: Histone H1 globular domain ordered; long IDRs flank |
| literature_ref: Ramakrishnan 1993 Nature |
| source: https://doi.org/10.1038/362219a0 |
| notes: '' |
| qc: |
| n_common_residues: 75 |
| n_common_core_lt3A: 75 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_HMGB1_1AABA_1AABA |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P09429 |
| query_pdb: 1AAB |
| query_chain: A |
| query_resi_range: 1..83 |
| query_length: 83 |
| state_a_pdb: 1AAB |
| state_a_chain: A |
| state_b_pdb: 1AAB |
| state_b_chain: A |
| target_state: A |
| expected_pattern_signature: 'HMGB1 box A: ordered when bound DNA; flexible apo termini' |
| literature_ref: Hardman 1995 Biochemistry |
| source: https://doi.org/10.1021/bi00050a012 |
| notes: '' |
| qc: |
| n_common_residues: 83 |
| n_common_core_lt3A: 83 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_NCOA1_1KBHB_1KBHB |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: Q15788 |
| query_pdb: 1KBH |
| query_chain: B |
| query_resi_range: 48..106 |
| query_length: 59 |
| state_a_pdb: 1KBH |
| state_a_chain: B |
| state_b_pdb: 1KBH |
| state_b_chain: B |
| target_state: A |
| expected_pattern_signature: NCOA1 NRID disorder-to-order helical when bound to CBP |
| literature_ref: Demarest 2002 Nature |
| source: https://doi.org/10.1038/nature724 |
| notes: '' |
| qc: |
| n_common_residues: 59 |
| n_common_core_lt3A: 59 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_NUMB_1WJ1A_1WJ1A |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P49757 |
| query_pdb: 1WJ1 |
| query_chain: A |
| query_resi_range: 1..156 |
| query_length: 156 |
| state_a_pdb: 1WJ1 |
| state_a_chain: A |
| state_b_pdb: 1WJ1 |
| state_b_chain: A |
| target_state: A |
| expected_pattern_signature: Numb PTB IDR disorder-to-order on peptide binding |
| literature_ref: Li 1998 EMBO J |
| source: https://doi.org/10.1093/emboj/17.24.7320 |
| notes: '' |
| qc: |
| n_common_residues: 156 |
| n_common_core_lt3A: 156 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_P27_1JSUC_1JSUC |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P46527 |
| query_pdb: 1JSU |
| query_chain: C |
| query_resi_range: 25..93 |
| query_length: 69 |
| state_a_pdb: 1JSU |
| state_a_chain: C |
| state_b_pdb: 1JSU |
| state_b_chain: C |
| target_state: A |
| expected_pattern_signature: p27 KID region disorder-to-order upon Cdk2/cyclinA binding |
| literature_ref: Russo 1996 Nature |
| source: https://doi.org/10.1038/382325a0 |
| notes: p27 alone is disordered; bound to Cdk2/CycA forms extended ordered conformation |
| qc: |
| n_common_residues: 69 |
| n_common_core_lt3A: 69 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_P53TAD_2K8FA_2K8FA |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: P04637 |
| query_pdb: 2K8F |
| query_chain: A |
| query_resi_range: 1..90 |
| query_length: 90 |
| state_a_pdb: 2K8F |
| state_a_chain: A |
| state_b_pdb: 2K8F |
| state_b_chain: A |
| target_state: A |
| expected_pattern_signature: p53 TAD2 disorder-to-order helical conformation |
| literature_ref: Lee 2010 PNAS |
| source: https://doi.org/10.1073/pnas.0915169107 |
| notes: '' |
| qc: |
| n_common_residues: 90 |
| n_common_core_lt3A: 90 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_PKID_1KDXB_1KDXB |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: Q01147 |
| query_pdb: 1KDX |
| query_chain: B |
| query_resi_range: 119..146 |
| query_length: 27 |
| state_a_pdb: 1KDX |
| state_a_chain: B |
| state_b_pdb: 1KDX |
| state_b_chain: B |
| target_state: A |
| expected_pattern_signature: pKID disorder-to-order upon KIX binding (CREB-CBP) |
| literature_ref: Radhakrishnan 1997 Cell |
| source: https://doi.org/10.1016/S0092-8674(00)80463-8 |
| notes: '' |
| qc: |
| n_common_residues: 27 |
| n_common_core_lt3A: 27 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_ID_PUMA_2M04B_2M04B |
| pattern: idp_idr_disorder_to_order |
| query_uniprot: Q9BXH1 |
| query_pdb: 2M04 |
| query_chain: B |
| query_resi_range: 68..92 |
| query_length: 25 |
| state_a_pdb: 2M04 |
| state_a_chain: B |
| state_b_pdb: 2M04 |
| state_b_chain: B |
| target_state: A |
| expected_pattern_signature: PUMA BH3-only IDR forms ordered helix bound to Bcl-xL |
| literature_ref: Rogers 2014 Structure |
| source: https://doi.org/10.1016/j.str.2014.02.005 |
| notes: '' |
| qc: |
| n_common_residues: 25 |
| n_common_core_lt3A: 25 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_OL_BARNASE_1A2PA_1YVSA |
| pattern: oligomer_domain_swap |
| query_uniprot: P00648 |
| query_pdb: 1A2P |
| query_chain: A |
| query_resi_range: 3..110 |
| query_length: 108 |
| state_a_pdb: 1A2P |
| state_a_chain: A |
| state_b_pdb: 1YVS |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Barnase monomer <-> engineered domain-swapped dimer |
| literature_ref: Zegers 1999 PNAS |
| source: https://doi.org/10.1073/pnas.96.3.818 |
| notes: '' |
| qc: |
| n_common_residues: 108 |
| n_common_core_lt3A: 70 |
| n_switch_region_ge3A: 38 |
| core_fraction: 0.648 |
| - case_id: SFB_OL_BCLXL_1LXLA_1R2DA |
| pattern: oligomer_domain_swap |
| query_uniprot: Q07817 |
| query_pdb: 1LXL |
| query_chain: A |
| query_resi_range: -3..217 |
| query_length: 221 |
| state_a_pdb: 1LXL |
| state_a_chain: A |
| state_b_pdb: 1R2D |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Bcl-xL monomer <-> domain-swapped dimer (apoptosis regulator) |
| literature_ref: Muchmore 1996 Nature |
| source: https://doi.org/10.1038/381335a0 |
| notes: '' |
| qc: |
| n_common_residues: 142 |
| n_common_core_lt3A: 125 |
| n_switch_region_ge3A: 17 |
| core_fraction: 0.88 |
| - case_id: SFB_OL_CALBD9K_4ICBA_1HT9A |
| pattern: oligomer_domain_swap |
| query_uniprot: P05937 |
| query_pdb: 4ICB |
| query_chain: A |
| query_resi_range: 0..75 |
| query_length: 76 |
| state_a_pdb: 4ICB |
| state_a_chain: A |
| state_b_pdb: 1HT9 |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Calbindin D9k monomer <-> domain-swapped dimer (EF-hand) |
| literature_ref: Hakansson 2001 Protein Sci |
| source: https://doi.org/10.1110/ps.06301 |
| notes: '' |
| qc: |
| n_common_residues: 76 |
| n_common_core_lt3A: 44 |
| n_switch_region_ge3A: 32 |
| core_fraction: 0.579 |
| - case_id: SFB_OL_CCL2_1DOKA_1DOMA |
| pattern: oligomer_domain_swap |
| query_uniprot: P13500 |
| query_pdb: 1DOK |
| query_chain: A |
| query_resi_range: 0..71 |
| query_length: 72 |
| state_a_pdb: 1DOK |
| state_a_chain: A |
| state_b_pdb: 1DOM |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: CCL2/MCP-1 monomer (1DOK) <-> dimer (1DOM) chemokine |
| assembly |
| literature_ref: Lubkowski 1997 Nat Struct Biol |
| source: https://doi.org/10.1038/nsb0197-64 |
| notes: '' |
| qc: |
| n_common_residues: 71 |
| n_common_core_lt3A: 66 |
| n_switch_region_ge3A: 5 |
| core_fraction: 0.93 |
| - case_id: SFB_OL_CVN_1IIYA_3EZMA |
| pattern: oligomer_domain_swap |
| query_uniprot: P81180 |
| query_pdb: 1IIY |
| query_chain: A |
| query_resi_range: 1..101 |
| query_length: 101 |
| state_a_pdb: 1IIY |
| state_a_chain: A |
| state_b_pdb: 3EZM |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Cyanovirin-N monomer <-> domain-swapped dimer (HIV-binding |
| lectin) |
| literature_ref: Yang 1999 JMB |
| source: https://doi.org/10.1006/jmbi.1999.3293 |
| notes: '' |
| qc: |
| n_common_residues: 101 |
| n_common_core_lt3A: 2 |
| n_switch_region_ge3A: 99 |
| core_fraction: 0.02 |
| - case_id: SFB_OL_CYSTC_3GAXA_1TIJA |
| pattern: oligomer_domain_swap |
| query_uniprot: P01034 |
| query_pdb: 3GAX |
| query_chain: A |
| query_resi_range: 12..120 |
| query_length: 107 |
| state_a_pdb: 3GAX |
| state_a_chain: A |
| state_b_pdb: 1TIJ |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Cystatin C monomer (3GAX) <-> domain-swapped dimer (1TIJ) |
| literature_ref: Janowski 2001 Nat Struct Biol |
| source: https://doi.org/10.1038/89638 |
| notes: '' |
| qc: |
| n_common_residues: 107 |
| n_common_core_lt3A: 56 |
| n_switch_region_ge3A: 51 |
| core_fraction: 0.523 |
| - case_id: SFB_OL_DTOX_1F0LA_1DDTA |
| pattern: oligomer_domain_swap |
| query_uniprot: P00588 |
| query_pdb: 1F0L |
| query_chain: A |
| query_resi_range: 1..535 |
| query_length: 520 |
| state_a_pdb: 1F0L |
| state_a_chain: A |
| state_b_pdb: 1DDT |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Diphtheria toxin monomer <-> domain-swapped dimer |
| literature_ref: Bennett 1994 Protein Sci |
| source: https://doi.org/10.1002/pro.5560030917 |
| notes: '' |
| qc: |
| n_common_residues: 520 |
| n_common_core_lt3A: 363 |
| n_switch_region_ge3A: 157 |
| core_fraction: 0.698 |
| - case_id: SFB_OL_ENGRAILED_1ENHA_2JWTA |
| pattern: oligomer_domain_swap |
| query_uniprot: P02836 |
| query_pdb: 1ENH |
| query_chain: A |
| query_resi_range: 3..56 |
| query_length: 54 |
| state_a_pdb: 1ENH |
| state_a_chain: A |
| state_b_pdb: 2JWT |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Engrailed homeodomain monomer <-> swapped dimer |
| literature_ref: Clarke 1994 Structure |
| source: https://doi.org/10.1016/S0969-2126(00)00006-7 |
| notes: '' |
| qc: |
| n_common_residues: 54 |
| n_common_core_lt3A: 51 |
| n_switch_region_ge3A: 3 |
| core_fraction: 0.944 |
| - case_id: SFB_OL_ETA_1AOHA_1AOHB |
| pattern: oligomer_domain_swap |
| query_uniprot: P00552 |
| query_pdb: 1AOH |
| query_chain: A |
| query_resi_range: 5..147 |
| query_length: 143 |
| state_a_pdb: 1AOH |
| state_a_chain: A |
| state_b_pdb: 1AOH |
| state_b_chain: B |
| target_state: B |
| expected_pattern_signature: Eta toxin monomer <-> swapped oligomeric form |
| literature_ref: Bennett 1995 PNAS |
| source: https://doi.org/10.1073/pnas.91.8.3127 |
| notes: '' |
| qc: |
| n_common_residues: 143 |
| n_common_core_lt3A: 143 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_OL_GB1SW_2QMTA_1Q9VA |
| pattern: oligomer_domain_swap |
| query_uniprot: P19909 |
| query_pdb: 2QMT |
| query_chain: A |
| query_resi_range: 1..56 |
| query_length: 56 |
| state_a_pdb: 2QMT |
| state_a_chain: A |
| state_b_pdb: 1Q9V |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Protein GB1 monomer <-> domain-swapped tetramer (engineered) |
| literature_ref: Byeon 2003 JMB |
| source: https://doi.org/10.1016/j.jmb.2003.08.005 |
| notes: '' |
| qc: |
| n_common_residues: 56 |
| n_common_core_lt3A: 0 |
| n_switch_region_ge3A: 56 |
| core_fraction: 0.0 |
| - case_id: SFB_OL_HIVPR_1HHPA_3HVPA |
| pattern: oligomer_domain_swap |
| query_uniprot: P03366 |
| query_pdb: 1HHP |
| query_chain: A |
| query_resi_range: 1..99 |
| query_length: 99 |
| state_a_pdb: 1HHP |
| state_a_chain: A |
| state_b_pdb: 3HVP |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: HIV-1 protease dimer interface conformation (1HHP) <-> |
| alternate (3HVP) |
| literature_ref: Spinelli 1991 Biochimie |
| source: https://doi.org/10.1016/0300-9084(91)90168-Z |
| notes: '' |
| qc: |
| n_common_residues: 97 |
| n_common_core_lt3A: 97 |
| n_switch_region_ge3A: 0 |
| core_fraction: 1.0 |
| - case_id: SFB_OL_IL5_1HULA_1HULB |
| pattern: oligomer_domain_swap |
| query_uniprot: P05113 |
| query_pdb: 1HUL |
| query_chain: A |
| query_resi_range: 5..112 |
| query_length: 108 |
| state_a_pdb: 1HUL |
| state_a_chain: A |
| state_b_pdb: 1HUL |
| state_b_chain: B |
| target_state: B |
| expected_pattern_signature: Interleukin-5 obligate domain-swapped homodimer |
| literature_ref: Milburn 1993 Nature |
| source: https://doi.org/10.1038/363172a0 |
| notes: '' |
| qc: |
| n_common_residues: 108 |
| n_common_core_lt3A: 106 |
| n_switch_region_ge3A: 2 |
| core_fraction: 0.981 |
| - case_id: SFB_OL_RNASA_7RSAA_1A2WA |
| pattern: oligomer_domain_swap |
| query_uniprot: P61823 |
| query_pdb: 7RSA |
| query_chain: A |
| query_resi_range: 1..124 |
| query_length: 124 |
| state_a_pdb: 7RSA |
| state_a_chain: A |
| state_b_pdb: 1A2W |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Bovine RNase A monomer (7RSA) <-> C-terminal domain-swapped |
| dimer (1A2W) |
| literature_ref: Liu 1998 Protein Sci |
| source: https://doi.org/10.1002/pro.5560070806 |
| notes: '' |
| qc: |
| n_common_residues: 124 |
| n_common_core_lt3A: 104 |
| n_switch_region_ge3A: 20 |
| core_fraction: 0.839 |
| - case_id: SFB_OL_STEFINB_1STFI_2OCTA |
| pattern: oligomer_domain_swap |
| query_uniprot: P04080 |
| query_pdb: 1STF |
| query_chain: I |
| query_resi_range: 6..125 |
| query_length: 98 |
| state_a_pdb: 1STF |
| state_a_chain: I |
| state_b_pdb: 2OCT |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: Stefin B monomer <-> domain-swapped dimer (cystatin |
| family) |
| literature_ref: Janowski 2001 Nat Struct Biol |
| source: https://doi.org/10.1038/89638 |
| notes: '' |
| qc: |
| n_common_residues: 68 |
| n_common_core_lt3A: 0 |
| n_switch_region_ge3A: 68 |
| core_fraction: 0.0 |
| - case_id: SFB_OL_SUC1_1PUCA_1SCEA |
| pattern: oligomer_domain_swap |
| query_uniprot: P14635 |
| query_pdb: 1PUC |
| query_chain: A |
| query_resi_range: 2..102 |
| query_length: 101 |
| state_a_pdb: 1PUC |
| state_a_chain: A |
| state_b_pdb: 1SCE |
| state_b_chain: A |
| target_state: B |
| expected_pattern_signature: p13suc1 closed monomer <-> beta-strand-swapped dimer |
| literature_ref: Bourne 1996 Cell |
| source: https://doi.org/10.1016/S0092-8674(00)81092-2 |
| notes: '' |
| qc: |
| n_common_residues: 97 |
| n_common_core_lt3A: 88 |
| n_switch_region_ge3A: 9 |
| core_fraction: 0.907 |
|
|
