Dockerfile

# Plant DNA Designer — container image for the FastAPI web app.
# Doubles as the Hugging Face Space image (sdk: docker, app_port: 7860).
#
#   docker build -t plant-dna-designer .
#   docker run -p 7860:7860 plant-dna-designer   # open http://localhost:7860
#
FROM python:3.12-slim

ENV PIP_NO_CACHE_DIR=1 \
    PYTHONUNBUFFERED=1 \
    PYTHONDONTWRITEBYTECODE=1

WORKDIR /app

# Core runtime dependencies (must install cleanly; all ship manylinux wheels for
# cp312, so no compiler is needed). matplotlib/pytest/httpx from requirements.txt
# are build/test-only and are intentionally excluded from the runtime image.
RUN pip install \
      "fastapi>=0.139.0" \
      "uvicorn[standard]>=0.50.2" \
      "jinja2>=3.1.6" \
      "pydantic>=2.13.4" \
      "biopython>=1.87" \
      "numpy>=2.5.0"

# Optional: ViennaRNA gives exact MFE / partition-function folding. The app falls
# back to a built-in Nussinov estimator when it is absent, so a failure here must
# NOT break the image — hence the guard.
RUN pip install "ViennaRNA>=2.7.2" \
      || echo "ViennaRNA unavailable; falling back to the built-in Nussinov fold."

# Application code (pure-Python core, API, and no-build web frontend).
COPY cool/ ./cool/

WORKDIR /app/cool
EXPOSE 7860
CMD ["python", "-m", "uvicorn", "api.main:app", "--host", "0.0.0.0", "--port", "7860"]