Instructions to use EdisonScientific/Ibis0-BED-Simulator with libraries, inference providers, notebooks, and local apps. Follow these links to get started.

Libraries

How to use EdisonScientific/Ibis0-BED-Simulator with Transformers:

# Use a pipeline as a high-level helper
from transformers import pipeline

pipe = pipeline("text-generation", model="EdisonScientific/Ibis0-BED-Simulator")
messages = [
    {"role": "user", "content": "Who are you?"},
]
pipe(messages)

# pip install -U transformers accelerate
# Load model directly
from transformers import AutoTokenizer, AutoModelForCausalLM

tokenizer = AutoTokenizer.from_pretrained("EdisonScientific/Ibis0-BED-Simulator")
model = AutoModelForCausalLM.from_pretrained("EdisonScientific/Ibis0-BED-Simulator", device_map="auto")
messages = [
    {"role": "user", "content": "Who are you?"},
]
inputs = tokenizer.apply_chat_template(
	messages,
	add_generation_prompt=True,
	tokenize=True,
	return_dict=True,
	return_tensors="pt",
).to(model.device)

outputs = model.generate(**inputs, max_new_tokens=256)
print(tokenizer.decode(outputs[0][inputs["input_ids"].shape[-1]:]))

Notebooks
Google Colab
Kaggle
Local Apps Settings

vLLM

How to use EdisonScientific/Ibis0-BED-Simulator with vLLM:

Install from pip and serve model

# Install vLLM from pip:
pip install vllm
# Start the vLLM server:
vllm serve "EdisonScientific/Ibis0-BED-Simulator"
# Call the server using curl (OpenAI-compatible API):
curl -X POST "http://localhost:8000/v1/chat/completions" \
	-H "Content-Type: application/json" \
	--data '{
		"model": "EdisonScientific/Ibis0-BED-Simulator",
		"messages": [
			{
				"role": "user",
				"content": "What is the capital of France?"
			}
		]
	}'

Use Docker

docker model run hf.co/EdisonScientific/Ibis0-BED-Simulator

SGLang

How to use EdisonScientific/Ibis0-BED-Simulator with SGLang:

Install from pip and serve model

# Install SGLang from pip:
pip install sglang
# Start the SGLang server:
python3 -m sglang.launch_server \
    --model-path "EdisonScientific/Ibis0-BED-Simulator" \
    --host 0.0.0.0 \
    --port 30000
# Call the server using curl (OpenAI-compatible API):
curl -X POST "http://localhost:30000/v1/chat/completions" \
	-H "Content-Type: application/json" \
	--data '{
		"model": "EdisonScientific/Ibis0-BED-Simulator",
		"messages": [
			{
				"role": "user",
				"content": "What is the capital of France?"
			}
		]
	}'

Use Docker images

docker run --gpus all \
    --shm-size 32g \
    -p 30000:30000 \
    -v ~/.cache/huggingface:/root/.cache/huggingface \
    --env "HF_TOKEN=<secret>" \
    --ipc=host \
    lmsysorg/sglang:latest \
    python3 -m sglang.launch_server \
        --model-path "EdisonScientific/Ibis0-BED-Simulator" \
        --host 0.0.0.0 \
        --port 30000
# Call the server using curl (OpenAI-compatible API):
curl -X POST "http://localhost:30000/v1/chat/completions" \
	-H "Content-Type: application/json" \
	--data '{
		"model": "EdisonScientific/Ibis0-BED-Simulator",
		"messages": [
			{
				"role": "user",
				"content": "What is the capital of France?"
			}
		]
	}'

Docker Model Runner
How to use EdisonScientific/Ibis0-BED-Simulator with Docker Model Runner:
```
docker model run hf.co/EdisonScientific/Ibis0-BED-Simulator
```

Ibis0-BED-Simulator / README.md

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---
license: apache-2.0
base_model: Qwen/Qwen3-30B-A3B
library_name: transformers
pipeline_tag: text-generation
datasets:
- EdisonScientific/EDB-Bio
language:
- en
tags:
- biology
- experimental-design
- simulation
---
# Ibis0 BED outcome simulator

[paper](ARXIV_URL) · [code](https://github.com/EdisonScientific/ibis0) · [data](https://huggingface.co/datasets/EdisonScientific/EDB-Bio)

The outcome simulator from the Bayesian experimental design (BED) experiments in **"Do Language Models Know
What Compelling Scientific Evidence Looks Like?"**. Given a candidate experiment with its result hidden, the
hypothesis θ′ that the experiment itself tests, and a requested valence, it generates a plausible outcome:
either compelling support for θ′ or a clear null. During experiment selection the two outcomes are weighted
by the belief model's p(θ′ | evidence) to estimate expected information gain. The belief model is
[Ibis0-30B-A3B-Classifier](https://huggingface.co/EdisonScientific/Ibis0-30B-A3B-Classifier).

## Clone and install ibis0

The prompt builder and BED scripts below live in the
[EdisonScientific/ibis0 code repository](https://github.com/EdisonScientific/ibis0).
Install Python 3.12 and [uv](https://docs.astral.sh/uv/), then clone and install the repository:

```bash
git clone --recurse-submodules https://github.com/EdisonScientific/ibis0.git
cd ibis0
uv sync --frozen --all-groups
```

Run the referenced scripts from this repository with `uv run python <script-path>`.
Local GPU inference requires Linux and a CUDA GPU.

## Use

[`build_theta_prime_sft.py`](https://github.com/EdisonScientific/ibis0/blob/main/scripts/data_pipeline/build_theta_prime_sft.py)
builds the simulator's prompts from an experiment, its hypothesis, and the requested outcome type.
[`bed_thetaprime.py`](https://github.com/EdisonScientific/ibis0/blob/main/scripts/analysis/rq5_bed/bed_thetaprime.py)
uses the simulator and classifier together to select experiments.

The simulator returns JSON with three fields: `supports_hypothesis` (`"yes"` or `"no"`),
`weight_of_evidence_decibans`, and `y`, which contains the simulated measurements for the domain.

## Licence

Apache-2.0. Fine-tuned from [Qwen/Qwen3-30B-A3B](https://huggingface.co/Qwen/Qwen3-30B-A3B) (Apache-2.0).

## Citation

```bibtex
@article{ibis0,
  title   = {Do Language Models Know What Compelling Scientific Evidence Looks Like?},
  author  = {Igoe, Conor and Grand, Gabriel and Koch, Zane and Bou, Albert and Moss, Eli and Hinks, Michaela M. and Rodriques, Samuel G. and White, Andrew and Narayanan, Siddharth},
  journal = {arXiv preprint arXiv:ARXIV_ID},
  year    = {2026}
}
```

	---
	license: apache-2.0
	base_model: Qwen/Qwen3-30B-A3B
	library_name: transformers
	pipeline_tag: text-generation
	datasets:
	- EdisonScientific/EDB-Bio
	language:
	- en
	tags:
	- biology
	- experimental-design
	- simulation
	---

	# Ibis0 BED outcome simulator

	[paper](ARXIV_URL) · [code](https://github.com/EdisonScientific/ibis0) · [data](https://huggingface.co/datasets/EdisonScientific/EDB-Bio)

	The outcome simulator from the Bayesian experimental design (BED) experiments in **"Do Language Models Know
	What Compelling Scientific Evidence Looks Like?"**. Given a candidate experiment with its result hidden, the
	hypothesis θ′ that the experiment itself tests, and a requested valence, it generates a plausible outcome:
	either compelling support for θ′ or a clear null. During experiment selection the two outcomes are weighted
	by the belief model's p(θ′ \| evidence) to estimate expected information gain. The belief model is
	[Ibis0-30B-A3B-Classifier](https://huggingface.co/EdisonScientific/Ibis0-30B-A3B-Classifier).

	## Clone and install ibis0

	The prompt builder and BED scripts below live in the
	[EdisonScientific/ibis0 code repository](https://github.com/EdisonScientific/ibis0).
	Install Python 3.12 and [uv](https://docs.astral.sh/uv/), then clone and install the repository:

	```bash
	git clone --recurse-submodules https://github.com/EdisonScientific/ibis0.git
	cd ibis0
	uv sync --frozen --all-groups
	```

	Run the referenced scripts from this repository with `uv run python <script-path>`.
	Local GPU inference requires Linux and a CUDA GPU.

	## Use

	[`build_theta_prime_sft.py`](https://github.com/EdisonScientific/ibis0/blob/main/scripts/data_pipeline/build_theta_prime_sft.py)
	builds the simulator's prompts from an experiment, its hypothesis, and the requested outcome type.
	[`bed_thetaprime.py`](https://github.com/EdisonScientific/ibis0/blob/main/scripts/analysis/rq5_bed/bed_thetaprime.py)
	uses the simulator and classifier together to select experiments.

	The simulator returns JSON with three fields: `supports_hypothesis` (`"yes"` or `"no"`),
	`weight_of_evidence_decibans`, and `y`, which contains the simulated measurements for the domain.

	## Licence

	Apache-2.0. Fine-tuned from [Qwen/Qwen3-30B-A3B](https://huggingface.co/Qwen/Qwen3-30B-A3B) (Apache-2.0).

	## Citation

	```bibtex
	@article{ibis0,
	title = {Do Language Models Know What Compelling Scientific Evidence Looks Like?},
	author = {Igoe, Conor and Grand, Gabriel and Koch, Zane and Bou, Albert and Moss, Eli and Hinks, Michaela M. and Rodriques, Samuel G. and White, Andrew and Narayanan, Siddharth},
	journal = {arXiv preprint arXiv:ARXIV_ID},
	year = {2026}
	}
	```