MambaMIM / README.md
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---
license: apache-2.0
pipeline_tag: image-segmentation
---
## [MIA'25] MambaMIM: Pre-training Mamba with State Space Token Interpolation and its Application to Medical Image Segmentation
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![MambaMIM](img/TOKI.png)
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<a href="https://scholar.google.com/citations?user=x1pODsMAAAAJ&hl=en" target="_blank">Fenghe Tang</a><sup>1,2</sup>,</span>
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<a target="_blank">Bingkun Nian</a><sup>3</sup>,</span>
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<a href="https://scholar.google.com/citations?user=ocAtNkkAAAAJ&hl=en" target="_blank">Yingtai Li</a><sup>1,2</sup>,</span>
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<a href="https://scholar.google.com/citations?user=Wo8tMSMAAAAJ&hl=en" target="_blank">Zihang Jiang</a><sup>1,2</sup>,</span>
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<a href="https://scholar.google.com/citations?user=tmx7tu8AAAAJ&hl=en" target="_blank">Jie Yang</a><sup>3</sup>,</span>
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<a href="https://scholar.google.com/citations?user=Vbb5EGIAAAAJ&hl=en" target="_blank"> Liu Wei</a><sup>3</sup>,</span>
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<a href="https://scholar.google.com/citations?user=8eNm2GMAAAAJ&hl=en" target="_blank">S.Kevin Zhou</a><sup>1,2</sup>
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<sup>1</sup>
<a href='https://en.ustc.edu.cn/' target='_blank'>School of Biomedical Engineering, University of Science and Technology of China</a>&emsp;
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<sup>2</sup> <a href='http://english.ict.cas.cn/' target='_blank'>Suzhou Institute for Advanced Research, University of Science and Technology of China</a>&emsp;
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<sup>3</sup> <a href='http://www.pami.sjtu.edu.cn/En/Home' target='_blank'>Department of Automation, Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University</a>
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​ [![arXiv](https://img.shields.io/badge/arxiv-2408.08070-b31b1b)](https://arxiv.org/pdf/2408.08070.pdf) [![github](https://img.shields.io/badge/github-MambaMIM-purple)](https://github.com/FengheTan9/MambaMIM) <a href="#LICENSE--citation"><img alt="License: Apache2.0" src="https://img.shields.io/badge/LICENSE-Apache%202.0-blue.svg"/></a>
## News
- **MambaMIM accepted by Medical Image Analyses (MIA'25) ! πŸ₯°**
- **Weights released ! 😎**
- **Code released !** 😘
- **Code and weights will be released soon !** 😘
- **[2024/08/16] Paper released !**
## TODOs
- [x] Paper released
- [x] Code released
- [x] Weight released
## Getting Started
### Download weights
| Name | Resolution | Intensities | Spacing | Weights |
| :------: | :----------: | :-----------: | :----------------: | :----------------------------------------------------------: |
| MambaMIM | 96 x 96 x 96 | [-175, - 250] | 1.5 x 1.5 x 1.5 mm | [Google Drive (87MB)](https://drive.google.com/file/d/1B3j5aRPxkDJqf8UPGKDiAjg2X85a3Kwx/view?usp=sharing) |
### Prepare Environments
```
conda create -n mambamim python=3.9
conda activate mambamim
pip install torch==1.13.0 torchvision==0.14.0 torchaudio==0.13.0 --extra-index-url https://download.pytorch.org/whl/cu117
pip install packaging timm==0.5.4
pip install transformers==4.34.1 typed-argument-parser
pip install numpy==1.21.2 opencv-python==4.5.5.64 opencv-python-headless==4.5.5.64
pip install 'monai[all]'
pip install monai==1.2.0
pip install causal_conv1d-1.2.0.post2+cu118torch1.13cxx11abiTRUE-cp38-cp38-linux_x86_64.whl
pip install mamba_ssm-1.2.0.post1+cu118torch1.13cxx11abiFALSE-cp38-cp38-linux_x86_64.whl
```
### Prepare Datasets
We recommend that you convert the dataset into the [nnUNet](https://github.com/MIC-DKFZ/nnUNet/blob/master/documentation/dataset_format.md) format.
```
└── MambaMIM
β”œβ”€β”€ data
β”œβ”€β”€ Dataset060_TotalSegmentator
└── imagesTr
β”œβ”€β”€ xxx_0000.nii.gz
β”œβ”€β”€ ...
β”œβ”€β”€ Dataset006_FLARE2022
└── imagesTr
β”œβ”€β”€ xxx_0000.nii.gz
β”œβ”€β”€ ...
└── Other_dataset
└── imagesTr
β”œβ”€β”€ xxx_0000.nii.gz
β”œβ”€β”€ ...
```
An example ```dataset.json``` will be generated in ```./data```
The content should be like below:
```json
{
"training": [
{
"image": "./Dataset060_TotalSegmentator/imagesTr/xxx_0000.nii.gz"
},
{
"image": "./Dataset006_FLARE2022/imagesTr/xxx_0000.nii.gz"
},
]
}
```
## Start Training
![MambaMIM](img/masking_consistency.png)
Run training on multi-GPU :
```sh
# An example of training on 4 GPUs with DDP
torchrun --nproc_per_node=4 --nnodes=1 --node_rank=0 --master_addr=localhost --master_port=12351 main.py --exp_name=debug --data_path=./data --model=mambamim --bs=16 --exp_dir=debug_mambamim_ddp_4
```
Run training on the single-GPU :
```sh
# An example of training on the single GPU
python main.py --exp_name=debug --data_path=./data --model=mambamim --bs=4 --exp_dir=debug_mambamim
```
## Fine-tuning
Load pre-training weights :
```python
# An example of Fine-tuning on BTCV (num_classes=14)
from models.network.hymamba import build_hybird
model = build_hybird(in_channel=1, n_classes=14, img_size=96).cuda()
model_dict = torch.load("mambamim_mask75.pth")
if model.load_state_dict(model_dict, strict=False):
print("MambaMIM use pretrained weights successfully !")
```
Downstream pipeline can be referred to [UNETR]([research-contributions/UNETR/BTCV at main Β· Project-MONAI/research-contributions (github.com)](https://github.com/Project-MONAI/research-contributions/tree/main/UNETR/BTCV)).
## Acknowledgements:
This code uses helper functions from [SparK](https://github.com/keyu-tian/SparK) and [HySparK](https://github.com/FengheTan9/HySparK).
## Citation
If the code, paper and weights help your research, please cite:
```
@article{tang2024mambamim,
title={MambaMIM: Pre-training Mamba with State Space Token-interpolation},
author={Tang, Fenghe and Nian, Bingkun and Li, Yingtai and Yang, Jie and Wei, Liu and Zhou, S Kevin},
journal={arXiv preprint arXiv:2408.08070},
year={2024}
}
```
## License
This project is released under the Apache 2.0 license. Please see the [LICENSE](LICENSE) file for more information.