RESULTS.md

Results Note Date: September 12, 2025 Version: 1.0.0 Commit: main-2025-09-12 DOI: 10.57967/hf/5917

Execution Details:

python run_pipeline.py --deterministic --seed 42

Environment:

• Python 3.10.8
• Environment hash:
• OS: Windows 10
• Hardware: CPU-only execution

Input Parameters:

• Ancestry profile: Native, Irish
• HLA matches: 2
• Prior exposures: SARS-CoV-2, Influenza-B
• Metabolic factor: 1.2
• Random seed: 42

Generated Sequences Analysis:

ID	Length	Score	Disorder	Cys Pairs	N-glyc	GRAVY	pI

Key Findings:

1. Length distribution: 43-563 amino acids
2. Personalization scores: 0.62-0.78
3. Disorder scores: 0.185-0.677
4. Glycosylation sites: 7 total (avg 1.0 per sequence)
5. Cysteine pairs: 3/7 sequences have paired cysteines

Validation Status:

• Environment: See environment.yaml
• Checksums: See checksums.sha256
• Full results: validation_results_20250912_152239.json

For reproduction:

1. Clone repository
2. Install dependencies from environment.yaml
3. Run: python run_pipeline.py --deterministic
4. Verify checksums