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Explainable-Acute-Leukemia-Mortality-Predictor

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 {
"framework": "Explainable-Acute-Leukemia-Mortality-Predictor",
"model": "Logistic Regression",
"created_at_utc": "2026-01-28T12:59:21.790386",
"schema": {
"features": [
"Age (years)",
"Gender",
"Ethnicity",
"Type of Leukemia",
"ECOG",
"Risk Assesment",
"WBCs on Admission\n ( x10^9/L)",
"Hb on Admission (g/L)",
"LDH on Admission (IU/L)",
"MDx Leukemia Screen 1",
"Pre-Induction bone marrow biopsy blasts %",
"Date of 1st Bone Marrow biopsy (Date of Diagnosis)",
"Post-Induction MRD",
"Date of 1st CR",
"First_Induction",
"death_date",
"last_followup_date",
"Thrombocytopenia",
"Bleeding",
"B Symptoms",
"Lymphadenopathy",
"CNS Involvement",
"Extramedullary Involvement",
"fish_inv16/cbfb_myh11",
"fish_t8;21/runx1_runx1t1",
"fish_t15;17/PML-RARA",
"fish_KMT2A-MLL/11q23",
"fish_BCR-ABL1/t9;22",
"fish_ETV6-RUNX1/t12;21",
"fish_TCF3_PBX1/t1;19",
"fish_IGH/14q32rearr",
"fish_CRLF2 rearr",
"fish_NUP214/9q34",
"fish_Other",
"fish_del7q/monosomy7",
"fish_TP53/del17p",
"fish_del13q",
"fish_del11q",
"Number of FISH alteration",
"ngs_FLT3",
"ngs_NPM1",
"ngs_CEBPA",
"ngs_DNMT3A",
"ngs_IDH1",
"ngs_IDH2",
"ngs_TET2",
"ngs_TP53",
"ngs_RUNX1",
"ngs_Other",
"ngs_spliceosome",
"No. of ngs_mutation"
],
"numeric": [
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"Hb on Admission (g/L)",
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"Date of 1st Bone Marrow biopsy (Date of Diagnosis)",
"Date of 1st CR",
"death_date",
"last_followup_date",
"Number of FISH alteration",
"No. of ngs_mutation"
],
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"First_Induction",
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"Extramedullary Involvement",
"fish_inv16/cbfb_myh11",
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"fish_KMT2A-MLL/11q23",
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"label": "Outcome Event"
},
"feature_reduction": {
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"l1_C": 1.0,
"selection_method": "SelectFromModel(L1 saga, threshold=median)",
"note": "If SVD is enabled, SHAP becomes component-level (less interpretable)."
},
"shap_background": {
"file": "background.csv",
"max_rows": 200,
"note": "Raw (pre-transform) background sample for SHAP LinearExplainer."
},
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"duration_units": "days",
"model": "CoxPHFitter (lifelines) with one-hot for categoricals",
"required_columns_any_of": {
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"Diagnosis Date",
"Dx Date"
],
"event": [
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"Death",
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],
"death": [
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"Death Date",
"Date of Death"
],
"censor": [
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"Last Follow up date",
"Last Follow-up Date",
"Last Seen Date"
]
},
"used_columns": {
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"event": "Outcome Event",
"death": "death_date",
"censor": "last_followup_date"
},
"notes": "Survival model trained successfully."
},
"positive_class": "1",
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}