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🧬 RareSeek-R1

A Specialized Language Model for Rare Disease Diagnosis and Clinical Reasoning

📖 Model Overview

RareSeek-R1 is a domain-specialized large language model tailored for rare-disease diagnostic reasoning, developed through a Progressive Parameter-Efficient Transfer Learning framework.

The model is first instruction-tuned on the clinically grounded RareMed-Corpus, a large, multi-source dataset deeply integrated from medical textbooks, guidelines, biomedical literature, and real-world EHR (Electronic Health Record) narratives. It is subsequently fine-tuned on RareMed-CoT, a high-fidelity corpus designed to instill explicit, stepwise clinical reasoning that aligns with real-world diagnostic workflows.

Figure 1: Overall framework and pipeline of RareSeek-R1. Figure 1: Overall framework and pipeline of RareSeek-R1.

🗄️ Dataset & Resources

📚 RareMedData: Access the comprehensive medical dataset used for training here:
👉 https://huggingface.co/datasets/TaoMedAI/RareMedData

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