README.md

---
license: apache-2.0
task_categories:
  - feature-extraction
language:
  - en
tags:
  - medical-imaging
  - computational-pathology
  - digital-pathology
  - immunohistochemistry
  - foundation-model
  - pan-cancer
  - feature-representation
  - pytorch
viewer: false
---

# ImmunoBench Feature Representations

## 🔍 Overview

<p align="left">

<b>
🤗 <a href="https://huggingface.co/datasets/AI4Pathology/ImmunoBench-image-features">Dataset</a> |
🌐 <a href="https://yanfang-research.github.io/ImmunoBench-Web/">Homepage</a> |
📄 <i>Paper (coming soon)</i> |
💻 <a href="https://github.com/yanfang-research/ImmunoBench">Code</a>
</b>

</p>

This repository provides **pre-extracted feature representations** from whole slide images (WSIs) from the **ImmunoBench** project, a large-scale benchmark designed for evaluating pathology foundation models in IHC-centered pathology workflows. ImmunoBench integrates data from 13,657 patients, 26,058 WSIs, 9,682,431 TMA-derived IHC images and 464,294 annotated patches, collected across 13 institutions, covering 27 organs, 43 clinical stains and 14,708 gene-encoded proteins.


<table>
<tr>
<td align="center" width="50%">
<img src="assets/dataset_circos.png" width="95%">
</td>

<td align="center" width="50%">
<img src="assets/task_sunburst.png" width="95%">
</td>
</tr>

<tr>
<td align="center">
<b>Figure 1.</b> ImmunoBench dataset overview
</td>

<td align="center">
<b>Figure 2.</b> ImmunoBench task taxonomy
</td>
</tr>
</table>

---

## 🔒 Access Policy

Access to this dataset is **restricted** and subject to approval.

To request access:
- Please contact the dataset maintainers using your **institutional email address**
- Clearly state your **affiliation, research purpose, and intended use**

> ⚠️ This dataset is provided **for academic research only**.  
> Commercial use is **strictly prohibited** without prior written permission.

---

## 🔄 Dataset Versioning & Updates

This dataset is part of an actively maintained benchmark and will be **continuously updated**.

- Current release: `HANCOCK` subset  
- Future releases may include:
  - Additional cohorts  
  - More foundation models  
  - Extended feature modalities  

All updates will be documented in this repository and the project homepage:
🌐 [Project Homepage](https://yanfang-research.github.io/ImmunoBench-Web/)

---

## ⚠️ Usage Notes

- These features are **pre-extracted representations**, not raw images  
- Performance may vary depending on downstream task design  
- Users are responsible for ensuring compliance with local data regulations  

---

## 🤝 Contributions

We welcome community contributions and collaborations.

If you would like to propose additional datasets, tasks, or benchmark extensions for inclusion in **ImmunoBench**, please contact us or open an issue in our GitHub repository.

💻 [GitHub Issues](https://github.com/yanfang-research/ImmunoBench/issues)

---

## 📫 Contact

For access requests, collaboration inquiries, or technical issues:

📧 **test@pjlab.org.cn**

---

## 📖 Citation

If you use this dataset in your research, please cite:

[*Citation information coming soon.*]

---