input stringlengths 79 665 | output stringlengths 3 6.34k |
|---|---|
### Instruction:
Please summerize the given abstract to a title
### Response:
COVID-19 vaccines: Current evidence and considerations
### Response:
| The coronavirus disease 2019 (COVID-19) pandemic is a global crisis, with devastating health, business and social impacts. Vaccination is a safe, simple, and effective way of protecting a person against COVID-19. By the end of August 2021, only 24.6% of the world population has received two doses of a COVID-19 vaccine.... |
### Instruction:
Please summerize the given abstract to a title
### Response:
[Pharmacotherapeutic options for SARS-CoV-2 infection / COVID-19]
### Response:
| There is currently no proven effective therapy for COVID-19 Without wishing to be exhaustive, the drugs most studied in this regard are presented below Each of the listed therapeutic options is considered experimental at this stage However, given the severe public health implications of the epidemic and the potentially... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Hydroxychloroquine and chloroquine in COVID-19: should they be used as standard therapy?
### Response:
| The pandemic of the new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has urged the nations to an unprecedented world-wide reaction, including an accelerated exploration of therapeutic options. In the absence of a vaccine and specifically designed antivirals, the medical community ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
A Veterinary Vaccine for SARS-CoV-2: The First COVID-19 Vaccine for Animals
### Response:
| As coronaviruses have a wide range of host species, many animals harbor these pathogens, however only a handful of them become severely infected [...]. |
### Instruction:
Please summerize the given abstract to a title
### Response:
COVID-19: Vaccine Delivery System, Drug Repurposing and Application of Molecular Modeling Approach
### Response:
| The acute respiratory syndrome coronavirus (SARS-CoV-2) has spread across the world, resulting in a pandemic COVID-19 which is a human zoonotic disease that is caused by a novel coronavirus (CoV) strain thought to have originated in wild or captive bats in the initial COVID outbreak region. The global COVID-19 outbreak... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Therapy of Type 2 Diabetes in Patients with SARS-CoV-2 Infection
### Response:
| COVID-19 infection poses an important clinical therapeutic problem, especially in patients with coexistent diseases such as type 2 diabetes. Potential pathogenetic links between COVID-19 and diabetes include inflammation, effects on glucose homeostasis, haemoglobin deoxygenation, altered immune status and activation of... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Systemic Medications of Dermatological Importance in COVID-19
### Response:
| Early December 2019 witnessed an international outbreak of a novel coronavirus (COVID 19) designated severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) Since then, a number of therapeutic molecules have been explored to have potential efficacy against the SARS-Cov-2 per se or its sequelae There are no Food an... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Immunopathological Roles of Neutrophils in Virus Infection and COVID-19
### Response:
| Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been spread around the world and is currently affecting global public health. Clinical evidence indicates that the elevated number of peripheral neutrophils and higher ratio of neutrophils-to-lymphoc... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Contribution of Nanotechnology in the Fight Against COVID-19
### Response:
| Coronavirus disease (COVID-19) is a respiratory infectious disease caused by a newly discovered virus strain, severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) This pandemic spread quickly across nations with a high mortality rate in immunocompromised patients This contagious disease posed a serious threat t... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Antiviral Potential of Nanoparticles-Can Nanoparticles Fight Against Coronaviruses?
### Response:
| Infectious diseases account for more than 20% of global mortality and viruses are responsible for about one-third of these deaths. Highly infectious viral diseases such as severe acute respiratory (SARS), Middle East respiratory syndrome (MERS) and coronavirus disease (COVID-19) are emerging more frequently and their w... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Vitamin D, zinc and glutamine: Synergistic action with OncoTherad immunomodulator in interferon signaling and COVID19 (Review)
### Response:
| Coronavirus disease 2019 (COVID19), caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV2), was identified in December, 2019 in Wuhan, China. Since then, it has continued to spread rapidly in numerous countries, while the search for effective therapeutic options persists. Coronaviruses, including SARS... |
### Instruction:
Please summerize the given abstract to a title
### Response:
A review on Remdesivir: A broad-spectrum antiviral molecule for possible COVID-19 treatment.
### Response:
| Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel coronavirus strain and the causative agent of COVID-19 was identified to have emerged in Wuhan, China, in December 2019 [1]. This pandemic situation and magnitude of suffering has led to global effort to find out effective measures for discovery of n... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Delivery Routes for COVID-19 Vaccines
### Response:
| The novel coronavirus, SARS-CoV-2, which causes COVID-19, has resulted in a pandemic with millions of deaths. To eradicate SARS-CoV-2 and prevent further infections, many vaccine candidates have been developed. These vaccines include not only traditional subunit vaccines and attenuated or inactivated viral vaccines but... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Drug delivery systems as Immunomodulators for therapy of infectious disease: relevance to COVID-19
### Response:
| The emergence of SARS-CoV-2, and the ensuing global pandemic, has resulted in an unprecedented response to identify therapies that can limit uncontrolled inflammation observed in patients with moderate to severe COVID-19. The immune pathology behind COVID-19 is complex and involves the activation and interaction of mul... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Management of sars-cov-2 (Covid-19) infection with special focus on use of hydroxychloroquine and lopinavir/ritonavir
### Response:
| Editor’s comment-A The covid-19 pandemic is the greatest challenge for the current generation of physicians, scientists and health administrators B Strict use of PPE, face masks, isolation and quarantine are the most effective methods of prevention of this infection C The immunomodulator hydroxychloroquine is approved ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
[Umifenovir and coronavirus infections: a review of research results and clinical practice]
### Response:
| Coronaviruses are known to cause acute respiratory infections. Antiviral therapy, including for COVID-19, is based on clinical practice, experimental data and trial results. The purpose of this review is to: provide and systematize actual preclinical data, clinical trials results and clinical practice for antiviral age... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Homeopathic Treatment for COVID-19-Related Symptoms: A Case Series
### Response:
| BACKGROUND: Severe acute respiratory syndrome due to coronavirus 2 (SARS CoV-2) is a novel infectious disease, which has quickly developed into a pandemic. The spectrum of COVID-19 symptoms is broad, ranging from a mild, self-limiting respiratory tract illness to severe progressive pneumonia, multi-organ failure and po... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Open Questions for Harnessing Autophagy-Modulating Drugs in the SARS-CoV-2 War
### Response:
| At a time when the world faces an emotional breakdown, crushing our dreams if not taking our lives, we realize that together we must fight the war against the COVID-19 outbreak even if almost the majority of the scientific community finds itself confined to home. Every day, like everyone else, we, scientists, listen to... |
### Instruction:
Please summerize the given abstract to a title
### Response:
COVID-19 occurring during Natalizumab treatment: a case report in a patient with extended interval dosing approach
### Response:
| BACKGROUND: The novel Coronavirus SARS-CoV-2, which was identified after a recent outbreak in Wuhan, China, in December 2019, has generated a global pandemic impacting over 200 countries around the world. Recent reports suggest that ACE2, which is the target protein to invade the host, has a ubiquitous presence in huma... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Interleukin‐6 Receptor Antagonist Therapy to Treat SARS‐CoV‐2 Driven Inflammatory Syndrome in a Renal Transplant Recipient
### Response:
| Coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a pandemic that is evolving rapidly at present with unprecedented global health and societal implications. Herein, we report a case of successful treatment of SARS‐CoV‐2 induced inflammatory syndrome by utiliza... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Arginine depletion as a therapeutic approach for patients with COVID-19
### Response:
| The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a source of significant morbidity and death worldwide, and effective treatments are urgently needed. Clinical trials have focused largely on direct antiviral therapies or on immunomodulation in patients with severe manifes... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Therapeutic Options for Treatment of COVID-19: A Review from Repur-posed Drugs to New Drug Targets.
### Response:
| A new virus pandemic, COVID-19, has instigated substantial damage to human wellness in terms of death and ailment, economic compromises along with restriction of daily routine life. There is a profound increase in the number of victims and causalities day by day. Thus far, there is no available treatment and vaccinatio... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Ivermectin the Promising Drug to Stave off the COVID-19 Crisis: A Review
### Response:
| The Coronavirus disease 2019 (COVID-19) outbreak, forcing us to face unprecedented moments in the world The huge devastating impact of the world due to the covid-19 attack causes the brink of no return However, there is no proven and specific treatment for Covid -19 Very few medications have received Emergency Use of A... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Metabolic Reprogramming in COVID-19
### Response:
| Plenty of research has revealed virus induced alternations in metabolic pathways, which is known as metabolic reprogramming. Studies focusing on COVID-19 have uncovered significant changes in metabolism, resulting in the perspective that COVID-19 is a metabolic disease. Reprogramming of amino acid, glucose, cholesterol... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Role of Polypeptide Inflammatory Biomarkers in the Diagnosis and Monitoring of COVID-19
### Response:
| The COVID-19 (coronavirus disease 2019) pandemic that took over the world in December 2019 has had everlasting devastating impacts on the lives of people globally. It manifests a huge symptom spectrum ranging from asymptomatic to critically ill patients with an unpredictable outcome. Timely diagnosis and assessment of ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications
### Response:
| COVID-19 is a severe infectious disease that has claimed >150,000 lives and infected millions in the United States thus far, especially the elderly population. Emerging evidence has shown the virus to cause hemorrhagic and immunologic responses, which impact all organs, including lungs, kidneys, and the brain, as well ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China
### Response:
| A novel coronavirus (2019-nCoV) originating in Wuhan, China presents a potential respiratory viral pandemic to the world population. Current efforts are focused on containment and quarantine of infected individuals. Ultimately, the outbreak could be controlled with a protective vaccine to prevent 2019-nCoV infection. W... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Therapeutic Potential of Metformin in COVID-19: Reasoning for Its Protective Role
### Response:
| Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections present with increased disease severity and poor clinical outcomes in diabetic patients compared with their nondiabetic counterparts. Diabetes/hyperglycemia-triggered endothelial dysfunction and hyperactive inflammatory and immune responses are cor... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Lithium and coronaviral infections. A scoping review.
### Response:
| The current rapid spread of the novel coronavirus (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) calls for a rapid response from the research community. Lithium is widely used to treat bipolar disorder, but has been shown to exhibit antiviral activity. This brief review took a systematic approach to identify ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Management of SARS-CoV-2 Infection: Key Focus in Macrolides Efficacy for COVID-19
### Response:
| Macrolides (e g , erythromycin, fidaxomicin, clarithromycin, and azithromycin) are a class of bacteriostatic antibiotics commonly employed in medicine against various gram-positive and atypical bacterial species mostly related to respiratory tract infections, besides they possess anti-inflammatory and immunomodulatory ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Gene therapies and COVID-19 vaccines: a necessary discussion in relation with viral vector-based approaches
### Response:
| The COVID-19 pandemic is adding an unanticipated concern for those affected by genetic diseases. Most of the new treatment achievements for these patients are made possible as a result of advances in viral-based products. Among them, adenoviruses (AdV) and especially adeno-associated viruses (AAV) are important players... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infections
### Response:
| The recent Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak poses a serious threat to public health. Here, we summarize recent advances in identifying human neutralizing monoclonal antibodies (mAbs) against MERS-CoV, describe their mechanisms of action, and analyze their potential for treatment of MERS-... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Evolutionary artificial intelligence based peptide discoveries for effective Covid-19 therapeutics
### Response:
| An epidemic caused by COVID-19 in China turned into pandemic within a short duration affecting countries worldwide. Researchers and companies around the world are working on all the possible strategies to develop a curative or preventive strategy for the same, which includes vaccine development, drug repurposing, plasm... |
### Instruction:
Please summerize the given abstract to a title
### Response:
A comprehensive update on the structure and synthesis of potential drug targets for combating the coronavirus pandemic caused by SARS‐CoV‐2
### Response:
| The outbreak of the coronavirus pandemic COVID‐19 created by its severe acute respiratory syndrome corona virus‐2 (SARS‐CoV‐2) variant, known for producing a very severe acute respiratory syndrome, has created an unprecedented situation by its continual assault around the world. The crisis caused by the SARS‐CoV‐2 vari... |
### Instruction:
Please summerize the given abstract to a title
### Response:
SUMO: a novel target for anti-coronavirus therapy.
### Response:
| Over the past 20 years, humankind has encountered three severe coronavirus outbreaks. Currently ongoing, COVID-19 (coronavirus disease 2019) was declared a pandemic due to its massive impact on global health and the economy. Numerous scientists are working to identify efficacious therapeutic agents for COVID-19, althou... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Convalescent plasma: A possible treatment of COVID-19 in India
### Response:
| In India, SARS-CoV-2 virus-induced coronavirus disease 2019 (COVID-19) has already infected close to 5500 people, causing the death of 164. While these numbers are not comparable with values observed for the USA, Italy, or Spain, given the population of India, and the fact that the pandemic is now in an exponential sta... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Antiviral activity of molnupiravir against COVID-19: a schematic review of evidences
### Response:
| BACKGROUND: The study was aimed at encapsulating the evidence of in vitro and in vivo antiviral activities of molnupiravir and its active form against highly pathogenic SARS-CoV-2, the pathogen responsible for COVID-19, and finding out the efficacy and safety of molnupiravir in clinical trials. MAIN BODY: Information o... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Immunology and controlling of coronaviruses; the current enemy for humanity: A review
### Response:
| The Severe Acute Respiratory Syndrome-related Coronavirus 2 (COVID-19 or SARS-CoV-2) epidemic is professed as world disaster producing a worrying increasing mortality, particularly amongst vulnerable humans worldwide. Whether COVID-19 has a strong ability for acceptable genetic flexibility that amended for breaking imm... |
### Instruction:
Please summerize the given abstract to a title
### Response:
How should we treat pregnant women infected with SARS‐CoV‐2?
### Response:
| The health crisis caused by the novel SARS-cov-2 (formally called 2019-nCoV) related pandemic requires urgent action, including a necessary therapeutic response. Pregnant women are just as exposed as the general population and should not be excluded, because of their status, from discussions on effective and well toler... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Food as medicine: A possible preventive measure against coronavirus disease (COVID-19)
### Response:
| The recent and ongoing outbreak of coronavirus disease (COVID-19) is a huge global challenge. The outbreak, which first occurred in Wuhan City, Hubei Province, China and then rapidly spread to other provinces and to more than 200 countries abroad, has been declared a global pandemic by the World Health Organization. Th... |
### Instruction:
Please summerize the given abstract to a title
### Response:
The advantages of drug treatment with statins in patients with SARS-CoV-2 infection
### Response:
| On 11 March 2020 the World Health Organization (WHO) declared a status of global pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease 2019, COVID-19). The pandemic is currently underway, and to date has caused approximately 2.42 million deaths worldwide. The first... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Drug discovery of small molecules for the treatment of COVID-19: A review on clinical studies
### Response:
| Recently, a sudden outbreak of novel coronavirus disease (COVID-19) was caused by a zoonotic virus known as severe acute respiratory syndrome coronavirus (SARS-CoV-2). It has caused pandemic situations around the globe and affecting the lives of millions of people. So far, no drug has been approved for the treatment of... |
### Instruction:
Please summerize the given abstract to a title
### Response:
The Importance of Cellular Immunity in the Development of Vaccines and Therapeutics for COVID-19
### Response:
| It is important to develop vaccines that can also mediate T-cell responses to SARS-CoV-2 to limit severity of infections, and to analyze the cellular immunome in the use of anti-SARS-CoV-2 therapeutics. |
### Instruction:
Please summerize the given abstract to a title
### Response:
Drug repurposing against COVID-19: focus on anticancer agents
### Response:
| BACKGROUND: The very limited time allowed to face the COVID-19 pandemic poses a pressing challenge to find proper therapeutic approaches. However, synthesis and full investigation from preclinical studies to phase III trials of new medications is a time-consuming procedure, and not viable in a global emergency, such as... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Combating COVID-19: Study of robotic solutions for COVID-19
### Response:
| Due to the ongoing coronavirus pandemic caused by the novel virus SARS-CoV-2, the healthcare professionals throughout the world are at the most significant risk of infection from the treatment of infected patients. The risk is not only limited to them, people working in the service sectors who are required to go out an... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Current status and strategic possibilities on potential use of combinational drug therapy against COVID-19 caused by SARS-CoV-2
### Response:
| The spread of new coronavirus infection starting December 2019 as novel SARS-CoV-2, identified as the causing agent of COVID-19, has affected all over the world and been declared as pandemic. Approximately, more than 8,807,398 confirmed cases of COVID-19 infection and 464,483 deaths have been reported globally till the... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
### Response:
| In the past two decades, the world has faced several infectious disease outbreaks. Ebola, Influenza A (H1N1), SARS, MERS, and Zika virus have had a massive global impact in terms of economic disruption, the strain on local and global public health. Most recently, the global outbreak of novel coronavirus 2019 (SARS-CoV-... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Review of Trial Therapies and Treatment for COVID-19: Lessons for Indonesia
### Response:
| The infectious disease from Coronavirus Disease 2019, or COVID-19, has quickly spread world-wide since 2019 Therapies for managing COVID-19 have yet to be confirmed as medication for the severe sickness that the disease may cause This study aimed to review the previous research of the efficacy of trial therapy and trea... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies
### Response:
| Coronavirus-19 (COVI-19) involves humans as well as animals and may cause serious damage to the respiratory tract, including the lung: coronavirus disease (COVID-19). This pathogenic virus has been identified in swabs performed on the throat and nose of patients who suffer from or are suspected of the disease. When COV... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Characterization of raloxifene as potential pharmacological agent against SARS-CoV-2 and its variants
### Response:
| The new coronavirus that emerged, called SARS-CoV-2, is the causative agent of the COVID-19 pandemic. The identification of potential drug candidates that can rapidly enter clinical trials for the prevention and treatment of COVID-19 is an urgent need, despite the recent introduction of several new vaccines for the pre... |
### Instruction:
Please summerize the given abstract to a title
### Response:
In quest of a new therapeutic approach in COVID-19: the endocannabinoid system
### Response:
| The SARS-Cov-2 virus caused a high morbidity and mortality rate disease, that is the COVID-19 pandemic. Despite the unprecedented research interest in this field, the lack of specific treatments leads to severe complications in a high number of cases. Current treatment includes antivirals, corticosteroids, immunoglobul... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Can phytotherapy with polyphenols serve as a powerful approach for the prevention and therapy tool of novel coronavirus disease 2019 (COVID-19)?
### Response:
| Much more serious than the previous severe acute respiratory syndrome (SARS) coronavirus (CoV) outbreaks, the novel SARS-CoV-2 infection has spread speedily, affecting 213 countries and causing â¼17,300,000 cases and â¼672,000 (â¼+1,500/day) deaths globally (as of July 31, 2020). The potentially fatal coronavirus di... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Stopping pandemics before they start: Lessons learned from SARS-CoV-2
### Response:
| The vaccine and drug discovery responses to COVID-19 have worked far better than could have been imagined. Yet by the end of 2021, more than 5 million people had died, and the pandemic continues to evolve and rage globally. This Review will describe how each of the vaccines, antibody therapies, and antiviral drugs that... |
### Instruction:
Please summerize the given abstract to a title
### Response:
A consensus statement on the use of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in relation to COVID-19 (corona virus disease 2019)
### Response:
| There has been a lot of speculation that patients with coronavirus disease 2019 (COVID-19) who are receiving angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) may be at increased risk for adverse outcomes We reviewed the available evidence, and have not found this to be the case We ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
A REVIEW on the ANTIPARASITIC DRUG IVERMECTIN for VARIOUS VIRAL INFECTIONS and POSSIBILITIES of USING IT for NOVEL SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2: NEW HOPE to TREAT CORONAVIRUS DISEASE-2019
### Response:
| The novel coronavirus infection has spread all over the world. With no specific drug or vaccine, the process of "drug repurposing"becomes a feasible solution. As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has 80% sequence similarity with the SARS-CoV, the nuclear import inhibitor "Ivermectin"(IVM) has... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Nanotechnology advances in pathogen- and host-targeted antiviral delivery: multipronged therapeutic intervention for pandemic control
### Response:
| The COVID-19 pandemic's high mortality rate and severe socioeconomic impact serve as a reminder of the urgent need for effective countermeasures against viral pandemic threats. In particular, effective antiviral therapeutics capable of stopping infections in its tracks is critical to reducing infection fatality rate an... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Cardiovascular Complications of COVID-19: Pharmacotherapy Perspective
### Response:
| Coronavirus disease of 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading rapidly the world over. The disease was declared “pandemic” by the World Health Organization. An approved therapy for patients with COVID-19 has yet to emerge; however, there are some me... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Identification and Development of Therapeutics for COVID-19
### Response:
| After emerging in China in late 2019, the novel Severe acute respiratory syndrome-like coronavirus 2 (SARS-CoV-2) spread worldwide and as of early 2021, continues to significantly impact most countries. Only a small number of coronaviruses are known to infect humans, and only two are associated with the severe outcomes... |
### Instruction:
Please summerize the given abstract to a title
### Response:
SARS-CoV-2: From the pathogenesis to potential anti-viral treatments
### Response:
| INTRODUCTION: The world is witnessing the spread of one of the members of Coronaviruses (CoVs) family, called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the 21st century. Considering the short time spent after its prevalence, limited information is known about the effect of the virus mechanism on d... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Effective Immune Functions of Micronutrients against SARS-CoV-2
### Response:
| The third coronavirus outbreak in the last two decades has caused significant damage to the world's economy and community health. The highly contagious COVID-19 infection has affected millions of people to date and has led to hundreds of thousands of deaths worldwide. Aside from the highly infectious nature of SARS-CoV... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Molecular Insights of SARS-CoV-2 Infection and Molecular Treatments.
### Response:
| The coronavirus disease emerged in December 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome-related coronavirus 2 (SARS-CoV-2) and its rapid global spread has brought an international health emergency and urgent responses for seeking efficient prevention and therapeutic treatment. This has led to imperative... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Current Paradigms in COVID-19 Research: Proposed Treatment Strategies, Recent Trends and Future Directions
### Response:
| BACKGROUND: Recent pandemic of coronavirus disease caused by a novel coronavirus SARS-CoV-2 in humans is the third outbreak by this family of viruses leading to an acute respiratory infection which has been a major cause of morbidity and mortality worldwide.The virus belongs to the genus, Betacoronavirus which has been... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Statins: Could an old friend help in the fight against COVID-19?
### Response:
| The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has overwhelmed healthcare systems requiring the rapid development of treatments, at least, to reduce COVID-19 severity. Drug repurposing offers a fast track. Here, we discuss the potential beneficial effects of statins in ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Role of 2-Deoxy-D-Glucose (2-DG) in COVID-19 disease: A potential game-changer
### Response:
| Virus infections can cause tissue damage in many ways. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a cause of the current COVID-19 pandemic, has been extensively studied so far to investigate its pathophysiology and evaluate its impact on the metabolic system of human cells. This has given a lead to s... |
### Instruction:
Please summerize the given abstract to a title
### Response:
A review on favipiravir: the properties, function, and usefulness to treat COVID-19.
### Response:
| INTRODUCTION At this time, there is no specific therapeutic or vaccine for treatment of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Hence, available drugs for treatment of other viral infections may be useful to treat COVID-19. AREAS COVERED The focus of the current review was studying the main ch... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Pharmacologicaltreatment of COVID-19: lights and shadows
### Response:
| At the end of December 2019, a novel coronavirus, the severe acute respiratory syndrome coronavirus 2, caused an outbreak of pneumonia spreading from Wuhan, Hubei province, to the whole country of China and then the entire world, forcing the World Health Organization to make the assessment that the coronavirus disease ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Understanding the dynamics of COVID-19; implications for therapeutic intervention, vaccine development and movement control
### Response:
| The COVID-19 disease is caused by the recently identified SARS-CoV-2 virus, thought to have originated in bats (Rhinolophus affinis), the virus being highly infective within the human population and spread by respiratory droplets, contaminated surfaces and close person-to-person contact. The virus is now pandemic and w... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Applications of Artificial Intelligence in Battling Against Covid-19: A Literature Review
### Response:
| Colloquially known as coronavirus, the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2), that causes CoronaVirus Disease 2019 (COVID-19), has become a matter of grave concern for every country around the world. The rapid growth of the pandemic has wreaked havoc and prompted the need for immediate reactions ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Practical Recommendations Relevant to the Use of Resistance Training for COVID-19 Survivors
### Response:
| The novel coronavirus disease (COVID-19) has emerged at the end of 2019 and caused a global pandemic. The disease predominantly affects the respiratory system; however, there is evidence that it is a multisystem disease that also impacts the cardiovascular system. Although the long-term consequences of COVID-19 are not... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Treatment considerations for Behçet disease in the era of COVID-19: A narrative review
### Response:
| COVID-19 is a multisystem disease caused by severe acute respiratory syndrome coronavirus 2. It has been declared a pandemic by the World Health Organization in March 2020 and the outbreak still keeps its impacts worldwide. Behçet disease (BD) is a multi-systemic vasculitis involving the skin, mucosa, eyes, joints, ner... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Combinatorial therapeutic trial plans for COVID-19 treatment armed up with antiviral, antiparasitic, cell-entry inhibitor, and immune-boosters
### Response:
| SARS-CoV-2, or novel coronavirus, is causing the fatal and contagious coronavirus disease-2019 (COVID-19) affecting thousands of people every single day. Researchers are continuously searching for any possible cure and/or vaccine, but no conclusive report is available till date. Like many others, we realize that a rapi... |
### Instruction:
Please summerize the given abstract to a title
### Response:
[SARS-CoV-2 infection: Available data on 15th April 2021]./ Infection à SARS-CoV-2 : connaissances au 15 avril 2021
### Response:
| INTRODUCTION: Since January 2020, when the first cases of SARS-CoV-2 infection were diagnosed in France, pulmonologists have been at the heart of the crisis and should be responsible for the management of acute COVID-19 (and any possible sequelae) BACKGROUND: Many drugs have been evaluated or are currently under evalua... |
### Instruction:
Please summerize the given abstract to a title
### Response:
A proposed insight into the anti-viral potential of metallic nanoparticles against novel coronavirus disease-19 (COVID-19)
### Response:
| Background: Over the last ten months since December 2019, the world has faced infectious emerging novel coronavirus disease-2019 (COVID-19) outbreaks that had a massive global impact affecting over 185 countries Main body: Emerging novel COVID-19 is a global health emergency on a pandemic scale that represents a terror... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Hospital Course of a Man With Viral Pneumonia Caused by COVID-19
### Response:
| The authors present a case of a man with pneumonia caused by COVID-19. There is currently no FDA-approved medical treatment or vaccine for COVID-19, so a variety of drugs and medicinal therapies have been repurposed for use in hospital settings and clinical studies while the medical community waits for a medication to ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Chinese herbal injections for Coronavirus Disease 2019 (COVID-19): A narrative review
### Response:
| BACKGROUND: The outbreak of Coronavirus disease 2019 (COVID-19) has caused more than 180 million infections and 3.9 million deaths. To date, emerging clinical evidence has shown the synergetic benefits of Chinese herbal injections in treating this contagious respiratory disease. This review aims to summarize and analyz... |
### Instruction:
Please summerize the given abstract to a title
### Response:
COVID-19: Guidelines for pharmacists in South Africa
### Response:
| Epidemiology. The virus, its modes of transmission and incubation period. Symptom identification, including the differentiation between influenza, allergic rhinitis, sinusitis and COVID-19. Social media myths and misinformation. Treatment guidelines and medicines that may need to be kept in stock. Treatment and prevent... |
### Instruction:
Please summerize the given abstract to a title
### Response:
The COVID-19 Ontology
### Response:
| MOTIVATION: The COVID-19 pandemic has prompted an impressive, worldwide response by the academic community. In order to support text mining approaches as well as data description, linking and harmonization in the context of COVID-19, we have developed an ontology representing major novel coronavirus (SARS-CoV-2) entiti... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Fighting against the second wave of COVID-19: Can honeybee products help protect against the pandemic?
### Response:
| Coronavirus Disease (COVID-19) has infected people in 210 nations and has been declared a pandemic on March 12, 2020 by the World Health Organization (WHO). In the absence of effective treatment and/or vaccines for COVID-19, natural products of known therapeutic and antiviral activity could offer an inexpensive, effect... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Medication Rule Analysis of the Diagnosis and Treatment Programs of Chinese Medicine for the Prevention and Treatment of COVID-19 in China
### Response:
| OBJECTIVES: To summarize the measures and rules of Chinese medicine (CM) and provide reference for clinical application in the prevention and treatment of coronavirus disease (COVID-19). METHODS: The data source was from CM COVID-19 prevention and treatment programs on government websites and official media websites of... |
### Instruction:
Please summerize the given abstract to a title
### Response:
The time to offer treatments for COVID-19
### Response:
| Background: COVID-19 has several overlapping phases. Treatments to date have focused on the late stage of disease in hospital. Yet, the pandemic is by propagated by the viral phase in out-patients. The current public health strategy relies solely on vaccines to prevent disease.Methods: We searched the major national re... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Functionalized Dendrimer Platforms as a New Forefront Arsenal Targeting SARS-CoV-2: An Opportunity
### Response:
| The novel human coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has caused a pandemic. There are currently several marketed vaccines and many in clinical trials targeting SARS-CoV-2. Another strategy is to repurpose approved drugs to decrease the burden of the COVID-19 (official name for the co... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Vagus Nerve Stimulation: A Potential Adjunct Therapy for COVID-19
### Response:
| The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19) through excessive end organ inflammation Despite improved understanding of the pathophysiology, management, and the great efforts worldwide to produce effective drugs, death rates of COVID-19 patients remai... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Current Progress and Challenges in the Design and Development of a Successful COVID-19 Vaccine
### Response:
| The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still a worldwide concern, with little to no sign of a decreasing trend There is a general consensus that normal life will be hampered until a safe and effective vaccine strategy is available and... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Adipose Stem Cells (ASCs) and Stromal Vascular Fraction (SVF) as a Potential Therapy in Combating (COVID-19)-Disease
### Response:
| A recent and interesting study reported improved respiratory activity after intravenous administration of mesenchymal stem cells (MSCs) into patients affected by coronavirus disease 2019 (COVID-19). These outcomes displayed that intravenous infiltration of MSCs is a safe and efficacy treatment for COVID-19 pneumonia, a... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Darunavir Ethanolate: Repurposing an Anti-HIV Drug in COVID-19 Treatment
### Response:
| Antivirals already on the market and expertise gained from the SARS and MERS outbreaks are gaining momentum as the most effective way to combat the coronavirus outbreak. SARS-CoV-2 has caused considerable mortality due to respiratory failure, highlighting the immediate need for successful therapies as well as the long-... |
### Instruction:
Please summerize the given abstract to a title
### Response:
A traditional Chinese medicine formula NRICM101 to target COVID-19 through multiple pathways: A bedside-to-bench study
### Response:
| COVID-19 is a global pandemic, with over 50 million confirmed cases and 1.2 million deaths as of November 11, 2020. No therapies or vaccines so far are recommended to treat or prevent the new coronavirus. A novel traditional Chinese medicine formula, Taiwan Chingguan Yihau (NRICM101), has been administered to patients ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Role of Homeopathy in Epidemics: Paving Way for a Plausible Solution in the Management of COVID-19/SARS-CoV-2 Infection
### Response:
| The emergence and spread of the novel coronavirus disease 2019 (COVID-19) from Wuhan, China, has become a global threat The high infectivity and drastic outcomes have made this a paramount health concern Effective therapy or vaccine to arrest the progress has still not been proved Homeopathy has a long reputation and e... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Confronting Covid-19 by exploring the possibility of vaccinating with live SARS-CoV-2 virus itself, via a route that would reduce the incidence of pulmonary complications
### Response:
| This article proposes that one should explore whether the pulmonary complications of Covid-19 can be reduced or avoided by bypassing the airway entry of the SARS-CoV-2 virus. This could possibly be achieved by injecting live SARS-CoV-2 virus intradermal (ID), subcutaneous, intra-muscular (IM) or intra-peritoneal (IP), ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments
### Response:
| Pandemic of coronavirus disease (COVID-19) is still pressing the healthcare systems worldwide. Thus far, the lack of available COVID-19-targeted treatments has led scientists to look through drug repositioning practices and exploitation of available scientific evidence for potential efficient drugs that may block biolo... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Fecal microbiota transplantation for COVID-19; a potential emerging treatment strategy
### Response:
| At the end of 2019, an emerging outbreak caused by Severe Acute Respiratory Syndrome (SARS)-CoV-2 that first reported from Wuhan, China. The first manifestations of patients infected with SARS-CoV-2 was flu-like symptoms, while other type of manifestations, especially gastrointestinal manifestations were discovered rec... |
### Instruction:
Please summerize the given abstract to a title
### Response:
The british variant of the new coronavirus-19 (Sars-cov-2) should not create a vaccine problem
### Response:
| Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly contagious virus that infects humans and a number of animal species causing coronavirus disease-19 (COVID-19), a respiratory distress syndrome which has provoked a global pandemic and a serious health crisis in most countries across our planet. CO... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Bovine Serum Albumin-Coated Niclosamide-Zein Nanoparticles as Potential Injectable Medicine against COVID-19
### Response:
| (1) Background: COVID-19 has affected millions of people worldwide, but countries with high experimental anti-SARS-CoV-2 vaccination rates among the general population respectively show progress in achieving general herd immunity in the population (a combination of natural and vaccine-induced acquired immunity), result... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Role of different types of nanomaterials against diagnosis, prevention and therapy of COVID-19
### Response:
| In 2019, a novel type of coronavirus emerged in China called SARS-COV-2, known COVID-19, threatens global health and possesses negative impact on people's quality of life, leading to an urgent need for its diagnosis and remedy. On the other hand, the presence of hazardous infectious waste led to the increase of the ris... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Combination antiviral therapy with lopinavir/ritonavir, arbidol and interferon-α1b for COVID-19
### Response:
| Since the outbreak of coronavirus disease (COVID-19) that was discovered in 2019 in Wuhan, China, no standard therapy guideline has been set despite the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its high infectivity. The globally pandemic outbreak suggests that COVID-19 was highly inf... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2
### Response:
| Abstract Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and has subsequently spread worldwide. In the absence of any antiviral or immunomodulatory therapies, the disease is spreading at an alarming rate. A possibility of a resurgence of COVID-19 in places ... |
### Instruction:
Please summerize the given abstract to a title
### Response:
COVID19db: a comprehensive database platform to discover potential drugs and targets of COVID-19 at whole transcriptomic scale
### Response:
| Many open access transcriptomic data of coronavirus disease 2019 (COVID-19) were generated, they have great heterogeneity and are difficult to analyze. To utilize these invaluable data for better understanding of COVID-19, additional software should be developed. Especially for researchers without bioinformatic skills,... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Identification of potential pan-coronavirus therapies using a computational drug repurposing platform
### Response:
| In the past 20 years, there have been several infectious disease outbreaks in humans for which the causative agent has been a zoonotic coronavirus. Novel infectious disease outbreaks, as illustrated by the current coronavirus disease 2019 (COVID-19) pandemic, demand a rapid response in terms of identifying effective tr... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Quality Assessment of the Clinical Trial Protocols Regarding Treatments for Coronavirus Disease 2019
### Response:
| Background: With the global spread of coronavirus disease 2019 (COVID-19), an increasing number of clinical trials are being designed and executed to evaluate t |
### Instruction:
Please summerize the given abstract to a title
### Response:
The Role of Type III Interferons in Human Disease.
### Response:
| PURPOSE This literature review summarizes the main immunological characteristics of type III interferons (IFN) and highlights the clinically relevant aspects and future therapeutic perspectives for these inflammatory molecules. SOURCE Relevant articles in PubMed MEDLINE from the first publication (2003) until 2020. N=1... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Pausing the Fight Against Malaria to Combat the COVID-19 Pandemic in Africa: Is the Future of Malaria Bleak?
### Response:
| Malaria remains a major global health burden, killing hundreds of thousands annually, especially in sub-Saharan Africa. In 2019, a Phase IV Expanded Programme on Immunization (EPI)-linked malaria vaccine implementation was underway. However, in December 2019, a novel pneumonia condition termed coronavirus disease 2019 ... |
End of preview. Expand in Data Studio
- Downloads last month
- 2