message stringlengths 7 18.7k | message_type stringclasses 3 values | message_id int64 0 2 | conversation_id int64 50.8k 898k | cluster float64 34 34 | __index_level_0__ int64 152k 2.69M |
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Answer this question truthfully | instruction | 0 | 50,786 | 34 | 151,948 |
A chest CT could be useful when a chest x-ray has inconclusive signs of pneumonia but the clinical manifestation suggest pneumonia. CT findings in pneumonia include: Airspace consolidation Ground-glass opacities Pleural effusion Hilar and/or mediastinal lymphadenopathy Bronchiectasis Tree-in-bud appereance
A chest CT can also help to assess reasons for therapy failure and complications, such as lung abscess, and pleural effusions. | output | 1 | 50,786 | 34 | 151,949 |
What role does CT play in the diagnosis of pneumonia? | input | 2 | 50,786 | 34 | 151,950 |
Answer this question truthfully | instruction | 0 | 51,276 | 34 | 153,418 |
In patients with varicella pneumonia, CT may demonstrate well-defined and ill-defined nodules diffusely throughout both lungs nodules with a surrounding halo of ground-glass opacity, patchy ground-glass opacity, and coalescence of nodules. | output | 1 | 51,276 | 34 | 153,419 |
Is a CT scan utilized for diagnosing chickenpox? | input | 2 | 51,276 | 34 | 153,420 |
Answer this question truthfully | instruction | 0 | 54,115 | 34 | 161,935 |
A chest CT scan is not routinely done in patients with pneumonia, but is a diagnostic test that may be useful when a chest x-ray is not conclusive. CT findings may include lobar consolidation, ground-glass opacities, pleural effusion, lymphadenopathy, and tree-in-bud appereance. | output | 1 | 54,115 | 34 | 161,936 |
What does a CT scan reveal for pneumonia? | input | 2 | 54,115 | 34 | 161,937 |
Answer this question truthfully | instruction | 0 | 54,766 | 34 | 163,888 |
Chest CT abnormalities among patients with MERS-CoV may include any of the following:
Extensive bilateral patchy opacities, predominantly in the lung bases and in the subpleural regions Pleural effusions septal thickening Peribronchovascular involvement Traction bronchiectasis and reticulation Evidence of architectural distortion | output | 1 | 54,766 | 34 | 163,889 |
What does the CT scan indicate for a Middle East respiratory syndrome coronavirus infection diagnosis? | input | 2 | 54,766 | 34 | 163,890 |
Please summerize the given abstract to a title | instruction | 0 | 77,240 | 34 | 231,310 |
Correlation of Indeterminate Lesiıons of Covid-19 Pneumonia Detected on Computed Tomography with RT-PCR Results. | output | 1 | 77,240 | 34 | 231,311 |
BACKGROUND The typical findings of COVID-19 pneumonia include multilobar ground-glass opacities and consolidation areas observed predominantly in the basal and peripheral parts of both lungs in computed tomography. OBJECTIVE The current study aimed to show the correlation of indeterminate lesions of COVID-19 pneumonia detected on computed tomography with the results of the reverse transcription-polymerase chain reaction (RT-PCR) test. METHODS Patients with high-resolution computed tomography images that were reported to contain indeterminate lesions in terms of COVID-19 pneumonia were included retrospectively in the study. The lesions were categorized and the patterns were classified. The RT-PCR-positive and the RT-PCR-negative patients were compared. P<0.05 was accepted as the statistical significance limit. RESULTS The RT-PCR-positive patients had a higher rate of the peripheral lesion. Limited consolidation areas were not detected in the RT-PCR-positive patients. In the RT-PCR-negative patients, the rates of acinar nodules and the tree-in-bud pattern were significantly higher. The RT-PCR-negative patients had higher nodular contour features and lesion coalescence. In the subgroup consisting of lesions with ground-glass opacities and/or ground-glass opacity around the nodule, the rate of nodular contour positivity was significantly higher in the RT-PCR- positive patients. CONCLUSION COVID-19 pneumonia can be suspected in peripheral indeterminate lesions. For indeterminate lesions, especially in the presence of the tree-in-bud pattern, acinar nodules, and limited consolidation areas, alternative diagnoses should be considered even these findings are accompanied by ground-glass opacities. | input | 2 | 77,240 | 34 | 231,312 |
Please summerize the given abstract to a title | instruction | 0 | 77,360 | 34 | 231,670 |
Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection | output | 1 | 77,360 | 34 | 231,671 |
In this retrospective study, chest CTs of 121 symptomatic patients infected with coronavirus disease-19 (COVID-19) from four centers in China from January 18, 2020 to February 2, 2020 were reviewed for common CT findings in relationship to the time between symptom onset and the initial CT scan (i.e. early, 0-2 days (36 patients), intermediate 3-5 days (33 patients), late 6-12 days (25 patients)). The hallmarks of COVID-19 infection on imaging were bilateral and peripheral ground-glass and consolidative pulmonary opacities. Notably, 20/36 (56%) of early patients had a normal CT. With a longer time after the onset of symptoms, CT findings were more frequent, including consolidation, bilateral and peripheral disease, greater total lung involvement, linear opacities, "crazy-paving" pattern and the "reverse halo" sign. Bilateral lung involvement was observed in 10/36 early patients (28%), 25/33 intermediate patients (76%), and 22/25 late patients (88%). | input | 2 | 77,360 | 34 | 231,672 |
Please summerize the given abstract to a title | instruction | 0 | 77,370 | 34 | 231,700 |
Variations In Spectrum Of Covid-19 Ct Findings And Its Severity Scoring In A Tertiary Care Hospital Of Bahawalpur, Southern Punjab Pakistan | output | 1 | 77,370 | 34 | 231,701 |
BACKGROUND: Recently the Coronavirus pandemic presented with different manifestations in different parts of the world, both on clinical examinations and on imaging CT Scanning (CT Scan) chest is used for detailed evaluation of the different characteristic patterns determining the depth of disease The study is aimed to assess the variations in spectrum of Covid-19 CT findings and relating severity (CT Severity Score) with the Clinical Symptoms in Bahawal Victoria Hospital, Bahawalpur METHODS: In this cross-sectional study, patients referred to radiology department from outdoor for COVID screening were included from 1st May to 30th June 2020 Mean age range of patients was calculated, while presenting complaints and co-morbidities were tabulated in frequencies and percentages after analysis Severity of symptoms and CT findings were correlated with biochemical and haematological tests RESULTS: Patients' age range from 25 to 85 years with 62% males and 38% females Statistically no significant difference was observed in CTSS on gender basis As sensitivity of RT PCR is about 70%, negative cases cannot be considered disease free and this is seen in this study as CT findings suggestive of COVID are seen in these patients Using 40-point CT-SS, 11 patients had a score of >19 with severe diseases, while 14 patients had common disease with a score range of 11-18 and 35 patients had <10 score with mild or no symptoms CONCLUSIONS: In this study, a spectrum of patchy ground glass opacities, bilateral peripheral predominantly lower lung consolidations were observed Quantitative analysis of inflammatory process as occurring in lungs in Coronavirus Disease 2019, using 40-point CTSS scoring on Imaging could provide a timely and objective approach towards identifying patients requiring intensive care and hospitalisation | input | 2 | 77,370 | 34 | 231,702 |
Please summerize the given abstract to a title | instruction | 0 | 77,378 | 34 | 231,724 |
Preoperative Noninvasive Mapping Allowed Targeted Concomitant Surgical Ablation and Revealed COVID-19 Infection | output | 1 | 77,378 | 34 | 231,725 |
In March 2020, a 64-year-old female with mitral valve insufficiency and persistent atrial fibrillation underwent preoperative noninvasive mapping for developing an ablation strategy. In the computed tomography (CT) scan, typical signs of COVID-19 were described. Since the consecutive polymerase chain reaction (PCR) test was negative, the severely symptomatic patient was planned for urgent surgery. Noninvasive mapping showed that atrial fibrillation was maintained by left atrial structures and pulmonary veins only. On admission day, the preoperative routine COVID-19 PCR test was positive, and after recovery, uneventful mitral valve repair with cryoablation of the left atrium and pulmonary veins was performed. Our case describes the potential benefit of preoperative noninvasive mapping for the development of a surgical ablation strategy, as well as the challenges in managing urgent surgical patients during the COVID-19 pandemic and the corresponding diagnostic relevance of CT. | input | 2 | 77,378 | 34 | 231,726 |
Please summerize the given abstract to a title | instruction | 0 | 77,483 | 34 | 232,039 |
Sensitivity of Lung US compared to Chest CT for the screening of COVID-19: preliminary report of our experience | output | 1 | 77,483 | 34 | 232,040 |
As lung ultrasound (LUS) is a noninvasive, radiation-free, repeatable and portable imaging tool suitable for a point-of-care use, several recent literature reports have emphasized its role as the ideal screening tool for SARS-CoV2 pneumonia. To evaluate the actual diagnostic accuracy of LUS for this purpose, we performed a systematic comparative study between LUS and CT scan findings in a population of 82 patients hospitalized because of COVID-19. LUS and Chest CT have been performed in all patients within 6-12 hours from the admission. The sensitivity of LUS in assessing typical CT findings was 60%. Despite LUS detected consolidations adherent to pleural surface in all cases, it was not able to detect all the consolidations assessed at CT scan (p=0.002), showing a risk to underestimate the actual disease’s extent. Moreover, only 70% of pleural surface is visible by LUS. Considering that the specificity and the positive predictive value of the same LUS signs may be lowered in a normal setting of non epidemic COVID-19 and in case of pre-existing cardio-pulmonary diseases, LUS use should not be indicated for diagnosis of COVID-19. However, it may be very useful for the assessment of pleural effusion and to guide safer fluid drainage. | input | 2 | 77,483 | 34 | 232,041 |
Please summerize the given abstract to a title | instruction | 0 | 77,642 | 34 | 232,516 |
High-resolution CT (HRCT) chest findings in PCR positive patients of covid-19 at combined military hospital Rawalpindi | output | 1 | 77,642 | 34 | 232,517 |
Objective: To study High resolution computed tomography chest findings in polymerase chain reaction (PCR) positive patients of COVID-19. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital Rawalpindi, from May to Jun 2020. Methodology: Study included high resolution computed tomography chest of 200 patients admitted to COVID ward who were polymerase chain reaction positive. Patients having previously diagnosed Interstitial lung disease were excluded. Informed consent from patients were taken. Different findings on High resolution computed tomography chest were summarized as percent of total cases. British society of thoracic imaging (BSTI) classification was used to classify high resolution computed tomography chest patterns of COVID-19 pneumonia. Results: Out of 200 patients included in study, 7 had previous changes on their chest imaging and were excluded. 193 patients (145 males and 48 females) enrolled had a median age of 52 years. One hundred and two patients (52.9%) showed classical pattern for COVID-19, 81 patients (41.9%) had indeterminate changes, 3 patients (1.6%) had atypical changes while 7 (3.6%) had normal high resolution computed tomography chest. Four had pleural effusions while 5 had mediastinal lymphadeno-pathy. One hundred and eight nine (97.9%) patients had bilateral lung involvement, 145 (75.1%) had central and peripheral while 48 (24.9%) had peripheral invol-vement only. One hundred and forteen (59%) patients had ground glass opacities while 70 (36.3%) had ground glass opacities with consolidation. Nine (4.7%) patients presented with consolidation only. Conclusion: High resolution computed tomography chest and COVID polymerase chain reaction done at the same time gives better diagnostic accuracy and helps in classifying these patients into different categories with early detection and treatment of patients. © 2021, Army Medical College. All rights reserved. | input | 2 | 77,642 | 34 | 232,518 |
Please summerize the given abstract to a title | instruction | 0 | 77,904 | 34 | 233,302 |
Case Report: Spontaneous Pneumothorax in Resolved, Uncomplicated COVID-19 Pneumonia-A Literature Review | output | 1 | 77,904 | 34 | 233,303 |
As the global COVID-19 pandemic has progressed, awareness of uncommon presentations and complications has increased. The actual incidence of spontaneous pneumothorax was found to be 0.66%, or six patients out of 902 who tested positive in recently published literature of 3368 patients (Zantah M, Dominguez Castillo E, Townsend R, Dikengil F, Criner GJ. Pneumothorax in COVID-19 disease-incidence and clinical characteristics. Respir Res. 2020 Sep 16;21(1):236.). Of those six patients, only two (0.22%) were not associated with mechanical ventilation barotrauma or comorbid lung disease such as COPD. Here, we present a spontaneous pneumothorax and pneumomediastinum in a patient four days after he had been discharged from hospitalization due to uncomplicated COVID-19 pneumonia. | input | 2 | 77,904 | 34 | 233,304 |
Please summerize the given abstract to a title | instruction | 0 | 78,161 | 34 | 234,073 |
Lung sonographic findings in COVID-19 patients | output | 1 | 78,161 | 34 | 234,074 |
OBJECTIVE: The objective of this study was to describe the lung sonographic findings of COVID-19 patients prospectively and investigate its association with disease severity. METHODS: This study was conducted in an emergency department and included consecutively enrolled laboratory confirmed COVID-19 patients. Lung sonography findings were described in all the included patients and analysed with respect to the clinical severity of the patients. RESULTS: 106 patients were included in the study. Common sonographic findings in COVID-19 patients were pleural line irregularity or shredding (70% of patients), followed by B - profile (59%), pleural line thickening (33%), occasional B - lines (26%), sub-pleural consolidations (35%), deep consolidations (6%), spared areas (13%), confluent B - lines or waterfall sign (14%) and pleural effusion (9%). These findings tended to be present more bilaterally and in lower lung zones. Sonographic characteristics like bilateral lung involvement, B - profile, spared areas and confluent B - lines or waterfall sign were significantly associated (p < 0.01) with clinical severity (more frequent with increasing disease severity). CONCLUSION: The lung sonographic findings of COVID-19 were found more bilaterally and in lower lung zones, and specific findings like B - profile, pleural thickening, spared areas and confluent B - lines or waterfall sign were associated with severe COVID-19. | input | 2 | 78,161 | 34 | 234,075 |
Please summerize the given abstract to a title | instruction | 0 | 78,205 | 34 | 234,205 |
Prognostic Significance of Chest Imaging by LUS and CT in COVID-19 Inpatients: The ECOVID Multicenter Study | output | 1 | 78,205 | 34 | 234,206 |
BACKGROUND: Point-of-care lung ultrasound (LUS) score is a semiquantitative score of lung damage severity. High-resolution computed tomography (HRCT) is the gold standard method to evaluate the severity of lung involvement from the novel coronavirus disease (COVID-19). Few studies have investigated the clinical significance of LUS and HRCT scores in patients with COVID-19. Therefore, the aim of this study was to evaluate the prognostic yield of LUS and of HRCT in COVID-19 patients. METHODS: We carried out a multicenter, retrospective study aimed at evaluating the prognostic yield of LUS and HRCT by exploring the survival curve of COVID-19 inpatients. LUS and chest CT scores were calculated retrospectively by 2 radiologists with >10 years of experience in chest imaging, and the decisions were reached in consensus. LUS score was calculated on the basis of the presence or not of pleural line abnormalities, B-lines, and lung consolidations. The total score (range 0–36) was obtained from the sum of the highest scores obtained in each region. CT score was calculated for each of the 5 lobes considering the anatomical extension according to the percentage parenchymal involvement. The resulting overall global semiquantitative CT score was the sum of each single lobar score and ranged from 0 (no involvement) to 25 (maximum involvement). RESULTS: One hundred fifty-three COVID-19 inpatients (mean age 65 ± 15 years; 65% M), including 23 (15%) in-hospital deaths for any cause over a mean follow-up of 14 days were included. Mean LUS and CT scores were 19 ± 12 and 10 ± 7, respectively. A strong positive linear correlation between LUS and CT scores (Pearson correlation r = 0.754; R2 = 0.568; p < 0.001) was observed. By ROC curve analysis, the optimal cut-point for mortality prediction was 20 for LUS score and 4.5 for chest CT score. According to Kaplan-Meier survival analysis, in-hospital mortality significantly increased among COVID-19 patients presenting with an LUS score ≥20 (log-rank 0.003; HR 9.87, 95% CI: 2.22–43.83) or a chest CT score ≥4.5 (HR 4.34, 95% CI: 0.97–19.41). At multivariate Cox regression analysis, LUS score was the sole independent predictor of in-hospital mortality yielding an adjusted HR of 7.42 (95% CI: 1.59–34.5). CONCLUSION: LUS score is useful to stratify the risk in COVID-19 patients, predicting those that are at high risk of mortality. | input | 2 | 78,205 | 34 | 234,207 |
Please summerize the given abstract to a title | instruction | 0 | 78,242 | 34 | 234,316 |
Evaluation for Myocarditis in Competitive Student Athletes Recovering From Coronavirus Disease 2019 With Cardiac Magnetic Resonance Imaging. | output | 1 | 78,242 | 34 | 234,317 |
Importance The utility of cardiac magnetic resonance imaging (MRI) as a screening tool for myocarditis in competitive student athletes returning to training after recovering from coronavirus disease 2019 (COVID-19) infection is unknown. Objective To describe the prevalence and severity of cardiac MRI findings of myocarditis in a population of competitive student athletes recovering from COVID-19. Design, Setting, and Participants In this case series, an electronic health record search was performed at our institution (University of Wisconsin) to identify all competitive athletes (a consecutive sample) recovering from COVID-19, who underwent gadolinium-enhanced cardiac MRI between January 1, 2020, and November 29, 2020. The MRI findings were reviewed by 2 radiologists experienced in cardiac imaging, using the updated Lake Louise criteria. Serum markers of myocardial injury and inflammation (troponin-I, B-type natriuretic peptide, C-reactive protein, and erythrocyte sedimentation rate), an electrocardiogram, transthoracic echocardiography, and relevant clinical data were obtained. Exposures COVID-19 infection, confirmed using reverse transcription-polymerase chain reaction testing. Main Outcomes and Measures Prevalence and severity of MRI findings consistent with myocarditis among young competitive athletes recovering from COVID-19. Results A total of 145 competitive student athletes (108 male and 37 female individuals; mean age, 20 years; range, 17-23 years) recovering from COVID-19 were included. Most patients had mild (71 [49.0%]) or moderate (40 [27.6%]) symptoms during the acute infection or were asymptomatic (24 [16.6%]). Symptoms were not specified or documented in 10 patients (6.9%). No patients required hospitalization. Cardiac MRIs were performed a median of 15 days (range, 11-194 days) after patients tested positive for COVID-19. Two patients had MRI findings consistent with myocarditis (1.4% [95% CI, 0.4%-4.9%]). Of these, 1 patient had marked nonischemic late gadolinium enhancement and T2-weighted signal abnormalities over multiple segments, along with an abnormal serum troponin-I level; the second patient had 1-cm nonischemic mild late gadolinium enhancement and mild T2-weighted signal abnormalities, with normal laboratory values. Conclusions and Relevance In this case series study, based on MRI findings, there was a low prevalence of myocarditis (1.4%) among student athletes recovering from COVID-19 with no or mild to moderate symptoms. Thus, the utility of cardiac MRI as a screening tool for myocarditis in this patient population is questionable. | input | 2 | 78,242 | 34 | 234,318 |
Please summerize the given abstract to a title | instruction | 0 | 78,282 | 34 | 234,436 |
Relationship between clinical types and radiological subgroups defined by latent class analysis in 2019 novel coronavirus pneumonia caused by SARS-CoV-2 | output | 1 | 78,282 | 34 | 234,437 |
OBJECTIVES: To investigate whether meaningful subgroups sharing the CT features of patients with COVID-19 pneumonia could be identified using latent class analysis (LCA) and explore the relationship between the LCA-derived subgroups and clinical types. METHODS: This retrospective review included 499 patients with confirmed COVID-19 pneumonia between February 11 and March 8, 2020. Subgroups sharing the CT features were identified using LCA. Univariate and multivariate logistic regression models were utilized to analyze the association between clinical types and the LCA-derived subgroups. RESULTS: Two radiological subgroups were identified using LCA. There were 228 subjects (45.69%) in class 1 and 271 subjects (54.31%) in class 2. The CT findings of class 1 were smaller pulmonary infection volume, more peripheral distribution, more GGO, more maximum lesion range ≤ 5 cm, a smaller number of lesions, less involvement of lobes, less air bronchogram, less dilatation of vessels, less hilar and mediastinal lymph node enlargement, and less pleural effusion than the CT findings of class 2. Univariate analysis demonstrated that older age, therapy, presence of fever, presence of hypertension, decreased lymphocyte count, and increased CRP levels were significant parameters associated with an increased risk for class 2. Multivariate analyses revealed that the patients with clinically severe type disease had a 1.97-fold risk of class 2 than the patients with clinically moderate-type disease. CONCLUSIONS: The demographic and clinical differences between the two radiological subgroups based on the LCA were significantly different. Two radiological subgroups were significantly associated with clinical moderate and severe types. KEY POINTS: • Two radiological subgroups were identified using LCA. • Older age, therapy, presence of fever, presence of hypertension, decreased lymphocyte count, and increased CRP levels were significant parameters with an increased risk for class 2 defined by LCA. • Patients with clinically severe type had a 1.97-fold higher risk of class 2 defined by LCA in comparison with patients showing clinically moderate-type disease. | input | 2 | 78,282 | 34 | 234,438 |
Please summerize the given abstract to a title | instruction | 0 | 78,352 | 34 | 234,646 |
The Electro-Anatomical Pathway for Normal and Abnormal ECGs in COVID Patients | output | 1 | 78,352 | 34 | 234,647 |
Patients with COVID-19 frequently have non-typical ECG changes in the QRS and T-wave morphology The novel CineECG uses using the mean temporal spatial isochrones (mTSI) to relate the activation and recovery pathway to the cardiac anatomy The aim of this feasib ility study is to use the novel CineECG to separate normal from abnormal ECGs The ECGs of 100 normal controls were used to obtain the normal mTSI paths values for the QRS, ST segment and T-wave These normal CineECG values were used to classify the COVID-19 ECGs as either as normal or abnormal of 107 patients being treatedfor COVID-19 in the University Medical Center Utrecht The CineECG was able to classify 98% of the normal ECG correctly and 94% of the abnormal ECG in comparison to expert ECG classifications The ability of the CineECG to relate the ECG to the cardiac anatomy supports the detection of abnormal ECGs The CineECG might be a novel ECG screening tool to detect potential cardiac involvement of the COVID-19 disease for non-ECG experts © 2020 Creative Commons;the authors hold their copyright | input | 2 | 78,352 | 34 | 234,648 |
Please summerize the given abstract to a title | instruction | 0 | 78,412 | 34 | 234,826 |
Fiber-optic Bronchoscopy in Patients Infected with Covid-19: a Case Series | output | 1 | 78,412 | 34 | 234,827 |
SESSION TITLE: Procedures Posters SESSION TYPE: Original Investigation Posters PRESENTED ON: October 18-21, 2020 PURPOSE: Bronchoscopy is a safe diagnostic and therapeutic tool Considering the increased number of COVID-19 cases worldwide, several associations issued guidelines regarding performance of bronchoscopy in patients with suspected/confirmed infection We present a series of patients with COVID-19 who underwent bronchoscopy METHODS: Retrospective review of patients admitted to BronxCare Health Hospital from April to May 2020 who had COVID-19 pneumonia and required emergent/urgent bronchoscopy We included only patients with positive nasopharyngeal swab test (SARS Coronavirus with CoV-2 RNA, Qual RT-PCR) Demographics and clinical- radiological information was obtained A safety check list was created which included all features recommended in current guidelines The additional recommendations included: bronchoscopy should be performed with patients sedated on ventilator;Stryker’s Hood Flyte Peel Away to be used to complement standard PPE;ventilator placed on stand-by every time patient is disconnected ie to connect/remove bronchoscopy adaptor, to insert/remove bronchoscope Once scope has been introduced into the airway, the procedure should be expedited as quickly as possible to minimize withdrawal and reintroduction of scope RESULTS: Six patients underwent bronchoscopy, 67% males, mean age 43 (range 29-80 years old) All patients had bilateral infiltrates on CXR Mean time from initial symptoms to bronchoscopy was 33 5 days (range 2-73 days) One patient was intubated for the bronchoscopy;the remaining 5 were on mechanical ventilator for respiratory failure Indication for bronchoscopy was lung collapse in 2 and persistent sepsis and fever despite antibiotics and negative cultures in the remainder 4 patients Bronchoscopy with bronchoalveolar lavage (BAL) was performed in all patient BAL fluid tested positive for SARS Coronavirus in 4 patients and 3 patients had positive bacterial cultures including identification of a multi-drug resistant pathogen The lung expanded in patients with collapse and change in antibiotics was done in 50% of patients based in BAL results Checklist was followed for all bronchoscopies;all personnel involved were followed for three weeks with daily temperature checks and symptoms monitoring Nobody has shown any symptoms of COVID-19 infection;neither had prior infection CONCLUSIONS: Bronchoscopy in patients infected with COVID-19, performed following strict safety measures are potentially safe and can help with patient care Emergency/ urgent procedures should not be delayed as bronchoscopy could change management in those patients Implications of finding positive BAL for COVID-19 are unclear but patients potentially are still infective CLINICAL IMPLICATIONS: We suggest careful evaluation of risk versus benefit of the bronchoscopy and strict, simple and standardized techniques for procedure performance in order to minimize risk of transmission DISCLOSURES: No relevant relationships by Gilda Diaz-Fuentes, source=Web Response No relevant relationships by Gabriella Roa Gomez, source=Web Response No relevant relationships by Sindhaghatta Venkatram, source=Web Response | input | 2 | 78,412 | 34 | 234,828 |
Please summerize the given abstract to a title | instruction | 0 | 78,505 | 34 | 235,105 |
Lung Scintigraphy Imaging Features in a Young Patient With COVID-19 | output | 1 | 78,505 | 34 | 235,106 |
A 31-year-old man developed diarrhea, fatigue, and intermittent fever for 2 weeks. The past few days he had experienced increasing dyspnea and dry cough. Ambulatory reverse transcriptase–polymerase chain reaction testing was positive for SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Because of elevated d-dimer (1.5 mg/L), a lung scintigraphy (V/Q scan) was performed as SPECT/CT. Ventilation SPECT showed reduced ventilation with central nuclide deposition, whereas perfusion SPECT was inconspicuous, excluding pulmonary embolism. However, the low-dose CT revealed bilateral ground-glass opacities as previously described in COVID-19. This case highlights the procedure and findings of V/Q scanning (without embolism) in COVID-19. | input | 2 | 78,505 | 34 | 235,107 |
Please summerize the given abstract to a title | instruction | 0 | 78,681 | 34 | 235,633 |
Abstract No. 183 Search for the offending clot and to filter or not: embolic versus thrombotic pulmonary embolism in COVID-19 | output | 1 | 78,681 | 34 | 235,634 |
Purpose: Emerging reports have shown an increased incidence of pulmonary embolism (PE) in hospitalized COVID-19 patients which subsequently worsens respiratory distress and can lead to further clinical deterioration. We sought to determine whether PE in Corona virus patients were more likely thrombotic or embolic in etiology, and the role of IVC filters in hospitalized COVID-19 patients. Materials and Methods: A single-center retrospective analysis evaluating all CT pulmonary angiograms (684) that were completed at the height of the COVID-19 pandemic between March 15, 2020, and May 31, 2020, at a tertiary care center in an urban setting. Deep venous thrombosis (DVT) was defined as iliocaval or femoropopliteal thrombus on lower extremity Doppler or CT with lower extremity runoff, or brachial, axillary, subclavian, or internal jugular vein thrombus on upper extremity Doppler. PE was considered thrombotic in patients in the absence of DVT and embolic in the presence of DVT during their inpatient stay. COVID-19 status was based on the most recent results prior to the patient’s CT pulmonary angiogram, if testing was not conducted, the patient was considered negative for COVID-19. Chi-square analysis was carried out to determine the difference in rates between thrombotic versus embolic PE in Corona virus positive and negative patients. Results: Imaging confirmed acute PE in 112 patients during this period, of which 43 (38%) tested positive for COVID-19, and 69 (62%) tested negative. Of patients testing positive for Corona virus with PE, imaging confirmed concurrent lower or upper extremity DVT in 4 of 43 patients (9%) and ruled out DVT in 24 of 43 patients (56%). Whereas, in COVID-19 negative patients with PE, imaging confirmation of DVT was seen in 19 of 69 patients (28%) and DVT was ruled out in 21 of 69 patients (30%). This correlated with a chi-square value of 8.12 (P = 0.004). Conclusions: Pulmonary emboli in COVID-19 patients are more likely to be thrombotic rather than embolic in etiology, limiting the utility of IVC filters in Corona virus patients. | input | 2 | 78,681 | 34 | 235,635 |
Please summerize the given abstract to a title | instruction | 0 | 78,906 | 34 | 236,308 |
Pulmonary Function and Chest CT in Patients Recovering From COVID-19 Pneumonia | output | 1 | 78,906 | 34 | 236,309 |
Background: COVID-19 is a new and highly contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is a paucity of data regarding long-term CT findings and pulmonary function in COVID-19 survivors. The aim of this study was to investigate the influence of COVID-19 pneumonia on pulmonary function and chest high-resolution computed tomography (CT) in convalescent patients. Methods: A retrospective study of COVID-19 pneumonia patients in the Beijing Youan Hospital, Capital Medical University, was conducted. Serial assessments, including pulmonary volumes (TLC), spirometry (VC, FVC, FEV1), pulmonary diffusing capacity for carbon monoxide (DLCO, DLCO/VA), and chest high-resolution CT were collected 3 months after discharge. Results: Forty-six patients completed the serial assessments. There were 38 non-severe and 8 severe cases. Abnormalities were detected in pulmonary function tests in 17 patients (37.8%). One (2.2%), 2 (4.3%), and 17 (37.8%) patients had FEV1/FVC ratio, TLC, and DLCO values less than 80% of predicted values, respectively. Twenty-eight patients (60.9%) had abnormal CT findings. Compared with patients with non-severe disease, those with severe disease had higher chest CT scores but a similar incidence of DLCO impairment. Similarly, patients who received glucocorticoids had higher chest CT scores but a similar incidence of DLCO impairment than those in the nonglucocorticoid group. Conclusions: Three months after discharge from the hospital, impaired diffusing capacity and CT abnormalities were detected in more than one third of COVID-19 patients. Compared with patients with non-severe disease, those with severe illness had a higher incidence of lung imaging abnormalities and similar lung function impairment. | input | 2 | 78,906 | 34 | 236,310 |
Please summerize the given abstract to a title | instruction | 0 | 79,162 | 34 | 237,076 |
Thoracic ultrasound and SARS-COVID-19: a pictorial essay | output | 1 | 79,162 | 34 | 237,077 |
Thoracic ultrasound seems to adapt to the screening for lung involvement of patients with suspected or ascertained SARS-COVID-19 infection due to its characteristics of easy applicability. It can be also a relevant method in monitoring patients. B lines are early finding of COVID-19, even in mild-symptomatic subjects; in the most serious cases such as pre-ARDS or ARDS, the B lines end up filling the ultrasound image almost completely, until it merges, so as to create a single hyperechoic image named as "white lung", with distortion and irregularity of the pleural line. In advanced stage, lung consolidations are present, representing pulmonary pathological areas that are no longer normally ventilated. | input | 2 | 79,162 | 34 | 237,078 |
Please summerize the given abstract to a title | instruction | 0 | 79,193 | 34 | 237,169 |
Pulmonary Embolism on CTPA in COVID-19 Patients | output | 1 | 79,193 | 34 | 237,170 |
BACKGROUND: Understanding pulmonary embolism (PE) rate and contributing comorbid, clinical, laboratory, and imaging characteristics may aid in management of pro-thombotic events in COVID-19 (COVID+) patients. PURPOSE: To evaluate PE prevalence on computed tomography pulmonary angiogram (CTPA) in COVID+ patients and factors associated with PE severity. MATERIALS AND METHODS: A retrospective, single-center study evaluated 62 COVID+ patients who underwent CTPA between March 13 and April 5, 2020. A 62-patient cohort who underwent CTPA prior to the first reported local COVID-19 case was retrogradely selected. The relative rate of CTPA-positivity was recorded. For the COVID+ cohort, comorbidities, laboratory values, clinical outcome, and venous thrombosis were recorded. Two thoracic radiologists assessed embolic severity using the Mastora system and evaluated right heart strain. Statistical analysis evaluated factors associated with PE and arterial obstruction severity. A P-value<.05 was considered significant. RESULTS: 37.1% of COVID+ patients had PE, higher than 14.5% of pre-COVID patients (P=.007). D-dimer levels closest to CTPA date correlated with Mastora obstruction score. ROC analysis identified optimal sensitivity (95%) and specificity (71%) for PE diagnosis at 1394 ng/mL DDU. The mean D-dimer was 1774 ng/mL and 6432 ng/mL DDU in CTPA-negative and CTPA-positive subgroups, respectively (P<.001). One additional CTPA-negative patient had DVT, for a total 38.7% with PE/DVT, despite 40% receiving prophylactic anticoagulation. Other factors did not demonstrate significant PE association. CONCLUSION: 37.1% of COVID+ CTPA exams diagnosed PE. PE can be a cause of decompensation in COVID+, and D-dimer can be used to stratify patients regarding PE risk and severity. | input | 2 | 79,193 | 34 | 237,171 |
Please summerize the given abstract to a title | instruction | 0 | 79,342 | 34 | 237,616 |
Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review | output | 1 | 79,342 | 34 | 237,617 |
Coronavirus disease 2019 (COVID-19) outbreak, first reported in Wuhan, China, has rapidly swept around the world just within a month, causing global public health emergency. In diagnosis, chest computed tomography (CT) manifestations can supplement parts of limitations of real-time reverse transcription polymerase chain reaction (RT-PCR) assay. Based on a comprehensive literature review and the experience in the frontline, we aim to review the typical and relatively atypical CT manifestations with representative COVID-19 cases at our hospital, and hope to strengthen the recognition of these features with radiologists and help them make a quick and accurate diagnosis. Key Points • Ground glass opacities, consolidation, reticular pattern, and crazy paving pattern are typical CT manifestations of COVID-19. • Emerging atypical CT manifestations, including airway changes, pleural changes, fibrosis, nodules, etc., were demonstrated in COVID-19 patients. • CT manifestations may associate with the progression and prognosis of COVID-19. | input | 2 | 79,342 | 34 | 237,618 |
Please summerize the given abstract to a title | instruction | 0 | 79,462 | 34 | 237,976 |
Clinical and CT characteristics which indicate timely radiological reexamination in patients with COVID-19: A retrospective study in Beijing, China | output | 1 | 79,462 | 34 | 237,977 |
Objective: Chest CT is useful in assessing the disease course of coronavirus disease-19 (COVID-19). This study aims to identify the characteristics of patients in whom imaging progression occurred while clinical symptoms were relieved and to guide radiological reexamination. Methods: This retrospective study included 73 patients with reverse transcription-polymerase chain reaction (RT-PCR) confirmed severe acute respiratory syndrome-2 (SARS-CoV-2) infection. All patients received CT reexaminations within 24 h after symptomatic remission. We divided patients into two groups according to the matching degree between clinical and imaging outcomes. Results: 21 patients displayed imaging progression while symptoms relieved. Patients with imaging progression were prone to be advanced in age [years: 60 (46–65) v 47 (37–60.75), P = 0.030]; lymphopenia (66.7% v 40.4%, P = 0.042) and low level of C-reactive protein [mg/L: 5.7 (1.9–20.2) v 18.9 (6.7–38.9), P = 0.038]. An age over 50 was an independent risk factor for imaging progression (OR = 3.41, 95%CI 1.14–10.20, P = 0.028). In CT images, they were inclined to present lesions with clear border (94.7% v 64.7%, P = 0.012), pure peripheral distribution (89.5% v 39.2%, P < 0.001), without bilateral lungs involved (57.9% v 29.4%, P = 0.028) especially with left lung involved only (42.1% v 17.6%, P = 0.034). Conclusion: In order to improve the therapeutic effect, the interval before radiological follow-up should be shortened appropriately especially in patients over the age of 50. It is essential to proceed to CT reexamination before symptomatic remission. | input | 2 | 79,462 | 34 | 237,978 |
Please summerize the given abstract to a title | instruction | 0 | 79,527 | 34 | 238,171 |
Are there overlapping clinical features between thoracic radiotherapy side effects and covid-19 pneumonia? radiation pneumonitis outside the radiation ports : three case reports | output | 1 | 79,527 | 34 | 238,172 |
Respiratory involvement of Covid-19 infection, presenting as a mild flu-like illness to potentially lethal acute respiratory distress syndrome is the main clinical manifestation in adults. Chest imaging shows a pictorial fashion of images due to the severity and stage of the disease, starting from focal nodular or mass-like opacities with air bronchogram to areas of ground glass consolidation or whited out lung. However, at the Covid-19 pandemic time, CT findings could yield confounding reporting in case of cancer patients previously treated with thoracic radiotherapy (tRT) due to atypical radiation pneumonitis occurring outside the radiation ports. Hypersensitivity pneumonitis and radiation induced bronchiolitis obliterans organizing pneumonitis (RT-BOOP) are accounted in this report. | input | 2 | 79,527 | 34 | 238,173 |
Please summerize the given abstract to a title | instruction | 0 | 79,560 | 34 | 238,270 |
Brain abnormalities in COVID-19 acute/subacute phase: A rapid systematic review | output | 1 | 79,560 | 34 | 238,271 |
OBJECTIVE: This systematic review aimed to synthesize early data on typology and topography of brain abnormalities in adults with COVID-19 in acute/subacute phase. METHODS: We performed systematic literature search via PubMed, Google Scholar and ScienceDirect on articles published between January 1 and July 05, 2020, using the following strategy and key words: ((covid[Title/Abstract]) OR (sars-cov-2[Title/Abstract]) OR (coronavirus[Title/Abstract])) AND (brain[Title/Abstract]). A total of 286 non-duplicate matches were screened for original contributions reporting brain imaging data related to SARS-Cov-2 presentation in adults. RESULTS: The selection criteria were met by 26 articles (including 21 case reports, and 5 cohort studies). The data analysis in a total of 361 patients revealed that brain abnormalities were noted in 124/361 (34%) reviewed cases. Neurologic symptoms were the primary reason for referral for neuroimaging across the studies. Modalities included CT (-angiogram, -perfusion, -venogram), EEG, MRI (-angiogram, functional), and PET. The most frequently reported brain abnormalities were brain white matter (WM) hyperintensities on MRI 66/124 (53% affected cases) and hypodensities on CT (additional 23% affected cases), followed by microhemorrhages, hemorrhages and infarcts, while other types were found in <5% affected cases. WM abnormalities were most frequently noted in bilateral anterior and posterior cerebral WM (50% affected cases). CONCLUSION: About a third of acute/subacute COVID-19 patients referred for neuroimaging show brain abnormalities suggestive of COVID-19-related etiology. The predominant neuroimaging features were diffuse cerebral WM hypodensities / hyperintensities attributable to leukoencephalopathy, leukoaraiosis or rarefield WM. | input | 2 | 79,560 | 34 | 238,272 |
Please summerize the given abstract to a title | instruction | 0 | 79,564 | 34 | 238,282 |
Tocilizumab effects in COVID-19 pneumonia: role of CT texture analysis in quantitative assessment of response to therapy | output | 1 | 79,564 | 34 | 238,283 |
PURPOSE: To evaluate CT and laboratory changes in COVID-19 patients treated with tocilizumab, compared to a control group, throughout a combined semiquantitative and texture analysis of images. MATERIALS AND METHODS: From March 11 to April 20, 2020, 57 SARS-CoV-2 positive patients were retrospectively compared: group T (n = 30) receiving tocilizumab and group non-T (n = 27) undergoing only antivirals/antimalarials. Chest-CT and laboratory findings were analyzed before and after treatment. CT evaluation included both semiquantitative scoring and texture analysis of all parenchymal lesions. Survival and recovery analyses were also provided with Kaplan–Meier method. RESULTS: In group T, no significant differences were found for CT score after treatment, while several texture features significantly changed, including mean attenuation (p < 0.0001), skewness (p < 0.0001), entropy (p = 0.0146) and higher-order parameters, suggesting considerable fading of parenchymal lesions. PaO(2)/FiO(2) mean value significantly increased after treatment, from 240 ± 93 to 363 ± 107 (p = 0.0003), with parallel decrease in inflammatory biomarkers (CRP, D-dimer and LDH). In group non-T, CT scoring, texture and laboratory parameters showed significant worsening at follow-up. Findings were clinically associated with opposite trends between two groups, with reduction of severe cases in group T (from 21/30 to 5/30; p < 0.0001) as compared to a significant worsening in group non-T (severe cases increasing from 6/27 to 14/27; p = 0.0473). Probability of discharge was significantly higher in group T (p < 0.0001), as well as survival rate, although not statistically significant. CONCLUSIONS: Our results suggest the potential role of CT texture analysis for assessing response to treatment in COVID-19 pneumonia, using Tocilizumab, as compared to semiquantitative evaluation, providing insight into the intrinsic parenchymal changes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11547-021-01371-7. | input | 2 | 79,564 | 34 | 238,284 |
Please summerize the given abstract to a title | instruction | 0 | 79,675 | 34 | 238,615 |
Undiagnosed sleep disorder breathing as a risk factor for critical COVID-19 and pulmonary consequences at the midterm follow-up | output | 1 | 79,675 | 34 | 238,616 |
INTRODUCTION: Patients with severe COVID-19 develops an acute respiratory distress syndrome (ARDS), requiring admission to the intensive care unit. COVID-19 also reports an increased prevalence of comorbidities, similar to patients with Sleep disorder breathing (SDB). OBJECTIVES: To evaluate the association between undiagnosed SDB and the risk of ARDS and pulmonary abnormalities in a cohort of patients’ survivors of COVID-19 between 3 to 6 months after diagnosis. METHODS: Prospective cohort study of patients who developed ARDS during hospitalization due to COVID-19 compared with a control group of patients who had COVID-19 with mild to moderate symptoms. All patients were evaluated between the 12(th) and 24(th) week after SARS-CoV-2 infection. The evaluation includes persistent symptoms, lung diffusing capacity of carbon monoxide (DLCO), chest CT scan and home sleep apnea test. SDB was diagnosed by the respiratory disturbance index ≥5 ev/h. The association between SDB and ARDS, the hazards of lung impairment and the hazard ratios (HR) were analyzed. RESULTS: A total of 60 patients were included (ARDS: 34 patients, Control: 26 patients). The mean follow-up was 16 weeks (range 12-24). ARDS reported a high prevalence of SDB (79% vs. 38% in control group). A total of 35% reported DLCO impairment, and 67.6% abnormal chest CT. SDB was independently associated to ARDS, OR 6.72 (CI, 1.56 – 28.93), p <0.01, and abnormal Chest CT, HR 17.2 (CI, 1.68 – 177.4, p=0.01). Besides, ARDS, days in mechanical ventilation, male gender were also associated with an increased risk of abnormal chest CT. CONCLUSION: Undiagnosed SDB is prevalent and independently associated with ARDS. In addition, undiagnosed SDB increased the hazard of abnormal Chest CT in the midterm. STUDY REGISTER: ISRCTN16865246. | input | 2 | 79,675 | 34 | 238,617 |
Please summerize the given abstract to a title | instruction | 0 | 79,716 | 34 | 238,738 |
Imaging manifestations and diagnostic value of chest CT of coronavirus disease 2019 (COVID-19) in the Xiaogan area | output | 1 | 79,716 | 34 | 238,739 |
AIM: To report the epidemiological, clinical, and radiological characteristics of patients with COVID-19 in Xiaogan, Hubei, China. MATERIALS AND METHODS: The complete clinical and imaging data of 114 confirmed COVID-19 patients treated in Xiaogan Hospital were analysed retrospectively. Data were gathered regarding the presence of chest computed tomography (CT) abnormalities; the distribution, morphology, density, location, and stage of abnormal shadows on chest CT; and observing the correlation between the severity of chest infection and lymphocyte ratio and blood oxygen saturation (SPO2) in patients. RESULTS: Chest CT revealed abnormal lung shadows in 110 patients. Regarding lesion distribution, multi-lobe lesions in both lungs were present in most patients (80 cases; 72.7%). Lesions most frequently involved both the peripheral zone and the central zone (62 cases; 56.4%). Regarding lesion morphology, 56 cases (50.1%) demonstrated patchy shadows that were partially fused into large areas. Thirty cases showed ground-glass opacity (27.3%), 30 cases showed the consolidation change (27.3%), and the remaining 50 cases showed both types of changes (45.4%). The progressing stage was the most common stage (54 cases; 49.1%). CT results showed a negative correlation with SPO2 and lymphocyte numbers (p<0.05), with r-values of -0.446 and -0.780, respectively. CONCLUSION: Spiral CT is a sensitive examination method, which can be applied to make an early diagnosis and for evaluation of progression, with a diagnostic sensitivity and accuracy better than that of nucleic acid detection. | input | 2 | 79,716 | 34 | 238,740 |
Please summerize the given abstract to a title | instruction | 0 | 79,766 | 34 | 238,888 |
Postmortem Ct Lung Findings in Decedents with Covid-19: a Review of 14 Decedents and Potential Triage Implications | output | 1 | 79,766 | 34 | 238,889 |
ABSTRACT OBJECTIVE Computed tomography has significant utility as a diagnostic tool for coronavirus disease 2019 (COVID-19) in the clinical setting COVID-19 deaths are sometimes examined by forensic pathologists, often in the setting of an unknown diagnosis We assessed the utility of postmortem computed tomography (PMCT) for use as a triage tool for these autopsy examinations MATERIALS AND METHODS We reviewed PMCT findings in 14 and histopathology in 11 decedents who were positive for COVID-19 RESULTS The predominant imaging findings were bilateral mixed densities, in either a diffuse or peripheral distribution, with traction bronchiectasis, and/or crazy paving In particular, traction bronchiectasis, ill-defined rounded consolidations, and reverse halo sign are useful when distinguishing from other postmortem changes CONCLUSION We conclude that triage with a PMCT may aid the forensic pathologist in diagnosing possible COVID-19 infection prior to autopsy examination | input | 2 | 79,766 | 34 | 238,890 |
Please summerize the given abstract to a title | instruction | 0 | 79,801 | 34 | 238,993 |
Successful treatment of a critically ill patient with acute respiratory distress syndrome from COVID-19 using mechanical ventilation strategy with low levels of positive end-expiratory pressure: A CARE-compliant case report | output | 1 | 79,801 | 34 | 238,994 |
INTRODUCTION: Acute respiratory distress syndrome (ARDS) secondary to COVID-19 is different from the ARDS caused by other infections. Conventional mechanical ventilation strategies using high levels of PEEP may not be beneficial and can even be harmful to patient with ARDS from COVID-19. So the ventilation strategies should be adjusted in order to improve the pulmonary ventilation function and oxygenation status, and outcomes of the patient. PATIENT CONCERNS: Herein, we present a 76-year-old male patient with ARDS secondary to COVID-19. We describe our experience with mechanical ventilation strategy and the changes in respiratory mechanics in the patient during treatment. DIAGNOSIS: The patient had tested positive for coronavirus (COVID-19) in nucleic acid test. Chest CT showed multiple ground glass shadows in both lungs. INTERVENTIONS: The patient received mechanical ventilation with low tidal volume and low PEEP. OUTCOMES: After treatment, the patients condition, as well as oxygenation status was improved, and he tested negative for the coronavirus several times. CONCLUSION: This case demonstrated that the low tidal volume with low levels of PEEP ventilation strategy may be more suitable for ARDS from COVID-19. | input | 2 | 79,801 | 34 | 238,995 |
Please summerize the given abstract to a title | instruction | 0 | 79,865 | 34 | 239,185 |
Design, validation, and clinical practice of standardized imaging diagnostic report for COVID-19. | output | 1 | 79,865 | 34 | 239,186 |
OBJECTIVES To design a standardized imaging diagnostic reporting mode for screening coronavirus disease 2019 (COVID-19), and to prospectively verify its effectiveness in clinical practice. METHODS A new classification and standardized imaging diagnosis report mode of viral pneumonia was established by studying and summarizing the imaging findings of various kinds of viral pneumonia, combining with lesion density, interstitial changes, pleural effusion, lymph nodes, and some special signs. After systematic training, the radiologist experienced clinical practice for screening CT features. COVID-19 cases were screened retrospectively in the single-center. The confirmed cases were verified, and the diagnostic efficacy of the standardized imaging reporting system in screening COVID-19 was tested. RESULTS There were 912 patients in this stage receiving the screening imaging examination. Of them, 190 patients were screened in the report mode and 30 patients were diagnosed as COVID-19. The CT manifestation of COVID-19 was characterized by pure ground glass lesions or with a few solid components, predominant subpleural distribution, no lymph node enlargement and pleural effusion, and often with paving-way sign and air bronchus sign. In combination with the above signs, the diagnostic efficacy of COVID-19 was 0.942. CONCLUSIONS The standardized imaging diagnosis report mode based on COVID-19 chest image features is effective and practical, which should be popularized. | input | 2 | 79,865 | 34 | 239,187 |
Please summerize the given abstract to a title | instruction | 0 | 79,918 | 34 | 239,344 |
Is Spontaneous Pneumomediastinum a Poor Prognostic Factor in Covid-19? | output | 1 | 79,918 | 34 | 239,345 |
OBJECTIVE To determine the risk factors for spontaneous pneumomediastinum (SPM), its clinical course and effect on prognosis in patients with Coronavirus disease-19 (COVID-19) pneumonia. STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY Kayseri City Training and Research Hospital, Turkey, from April to September 2020. METHODOLOGY All COVID-19 patients' clinical, laboratory, and radiologic characteristics, as well as treatment outcome data, were obtained through medical record extraction. Group A had 50 patients (22 men and 28 women) without SPM, and Group B had 20 patients (10 men and 10 women) with SPM. RESULTS Considering the accompanying comorbidities, the frequencies of asthma and inhaler-use was significantly higher in Group B than in Group A (p <0.05). In the CT evaluation at presentation, the rate of involvement of all five lobes of the lung in Group B was significantly higher than in Group A. Rates of tube thoracostomy, mechanical ventilator requirement, length of stay in hospital, and exitus were significantly higher in Group B than in Group A (p <0.05). CONCLUSION SPM development in a patient with COVID-19 pneumonia is a sign that the prognosis will not be good, and these patients need a more aggressive treatment. Key Words: Spontaneous pneumomediastinum, COVİD-19, Pneumothorax, Real-time polymerase chain reaction, Subcutaneous emphysema. | input | 2 | 79,918 | 34 | 239,346 |
Please summerize the given abstract to a title | instruction | 0 | 79,935 | 34 | 239,395 |
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