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Vitamin D should be orally supplemented in breastfed infants.
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| Which vitamin is recommended for oral supplementation in breastfed infants? |
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Vitamin C deficiency can result in a weakened immune response.
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| How can vitamin C deficiency impact the immune system? |
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The role of vitamin D (cholecalciferol) in the body is to increase both calcium (Ca2+) and phosphate plasma concentrations, which promotes bone mineralization. Vitamin D is essential for maintaining strong and healthy bones, and it works by increasing the ... | What is the role of vitamin D (cholecalciferol) in the body? |
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Association between vitamin D level and prognostic factors among patients infected with SARS-CoV-2.
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| OBJECTIVES The present study aimed to evaluate the presence of any relationship between vitamin D and prognostic factors among patients infected with SARS-CoV-2. METHODS This retrospective cross-sectional study was conducted among patients admitted from March to August 2020 in a referral hospital, Tehran, Iran. All pat... |
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Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2
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| Systemic pools of ATP are elevated in individuals homozygous for cystic fibrosis (CF) as evidenced by elevated blood and plasma ATP levels. This elevated ATP level seems to provide benefit in the presence of advanced solid tumors (Abraham et al., Nature Medicine 2(5):593–596, 1996). We published in this journal a paper... |
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Antiviral Activity of Vitamin D and COVID 19: Current Understanding
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| Innate and adaptive immune responses, which are intimately related to the evolution of many infectious diseases, are influenced by the biologically active form of vitamin D. From a mechanical perspective, there are several rationales to assume that vitamin D positively modifies host responses to SARS-CoV-2, either in t... |
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Can Melatonin Be a Potential “Silver Bullet” in Treating COVID-19 Patients?
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| The therapeutic potential of melatonin as a chronobiotic cytoprotective agent to counteract the consequences of COVID-19 infections has been advocated. Because of its wide-ranging effects as an antioxidant, anti-inflammatory, and immunomodulatory compound, melatonin could be unique in impairing the consequences of SARS... |
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Low 25(OH)D Level Is Associated with Severe Course and Poor Prognosis in COVID-19
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| We evaluated associations between serum 25-hydroxyvitamin D [25(OH)D] level and severity of new coronavirus infection (COVID-19) in hospitalized patients. We assessed serum 25(OH)D level in 133 patients aged 21–93 years. Twenty-five (19%) patients had severe disease, 108 patients (81%) had moderate disease, and 18 (14%... |
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Gut microbiome, Vitamin D, ACE2 interactions are critical factors in immune-senescence and inflammaging: key for vaccine response and severity of COVID-19 infection
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| BACKGROUND: The SARS-CoV-2 pandemic continues to spread sporadically in the Unites States and worldwide. The severity and mortality excessively affected the frail elderly with co-existing medical diseases. There is growing evidence that cross-talk between the gut microbiome, Vitamin D and RAS/ACE2 system is essential f... |
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Position paper of the Italian association of medical specialists in dietetics and clinical nutrition (ANSISA) on nutritional management of patients with COVID-19 disease
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| COVID-19 disease is characterized by serious clinical manifestations which could require urgent hospitalization. Prolonged hospitalization, with catabolism and immobilization, induces a decrease in weight and muscle mass which can result in sarcopenia, a condition that impairs respiratory and cardiac function, worsenin... |
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Is malaria immunity a possible protection against severe symptoms and outcomes of COVID-19?
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| Malaria-endemic areas of the world are noted for high morbidity and mortality from malaria. Also noted in these areas is the majority of persons in the population having acquired malaria immunity. Though this acquired malaria immunity does not prevent infection, it resists the multiplication of Plasmodium parasites, re... |
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Co-infection of SARS-CoV-2 and Bordetella bronchiseptica in a young man with idiopathic non-cystic bronchiectasis and vitamin D3 deficiency
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| This is the first reported case, to our knowledge, of co-infection of Bordetella bronchiseptica and SARS-CoV-2 in a young patient with underlying idiopathic bronchiectasis and vitamin D3 deficiency that was treated successfully with a combination therapeutic regime integrating doxycycline, empiric therapies for COVID-1... |
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Neem (Azadirachta Indica A. Juss) Capsules for Prophylaxis of COVID-19 Infection: A Pilot, Double-Blind, Randomized Controlled Trial
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| CONTEXT: SARS-CoV-2 is a global public-health concern Interventions to prevent infection are urgently needed The anti-inflammatory and antiviral effects of neem make it a potential agent for COVID-19 prophylaxis OBJECTIVE: The study intended to evaluate the prophylactic effects of neem capsules for persons at high risk... |
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Effectiveness of flax seed, an immune booster functional food during COVID-19 pandemic situation
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| During current COVID- 19 pandemic situation where preventive and curative medicines are unavailable, strong immune system is one of the best weapons to deal with it at individual level. Functional foods and dietary modification can decrease any kind of infections (viral as well as other infections) risk including COVID... |
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The potential link between inherited G6PD deficiency, oxidative stress, and vitamin D deficiency and the racial inequities in mortality associated with COVID-19()
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| There is a marked variation in mortality risk associated with COVID-19 infection in the general population. Low socioeconomic status and other social determinants have been discussed as possible causes for the higher burden in African American communities compared with white communities. Beyond the social determinants,... |
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Review Paper on Ayush System of Medicine against COVID-19
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| Corona kadha includes the ingredients such as elaichi,turmeric,cloves,black peppercorns,honey, jaggery,munakka,tulsi,cinnamon,etc which act as immunity boosters which boosts the immunity Immunity helps to fight against the covid-19 Mechanism of kadha is immunity boosting Arsenium album proved to be a immuno booster pil... |
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Vitamin D and its' role in Parkinson's disease patients with SARS-CoV-2 infection. A review article
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| A novel coronavirus reportedly called 2019-nCoV started to spread around the world at the end of 2019. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was later renamed after links with SARS were observed. Multiple studies have reported possible connections between the COVID-19 virus and neurodegenerative ... |
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Cortisol level dysregulation and its prevalence—Is it nature's alarm clock?
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| This review examines the stress hormone cortisol which plays an important role in regulating and supporting different bodily functions. Disruption in cortisol production has an impact on health and this review looks at a wide range of papers where cortisol has been indicated as a factor in numerous chronic conditions—e... |
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Blood factors as biomarkers in osteoporosis: points from the COVID-19 era
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| The restrictions adopted during the coronavirus disease 2019 (COVID-19) pandemic limiting direct medical consultations and access to healthcare centers reduced the participation of patients with chronic diseases, such as osteoporosis (OP), in screening and monitoring programs. This highlighted the need for new screenin... |
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Vitamin D status of children with paediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (PIMS-TS)
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| Coronavirus disease 2019 (COVID-19) has caused mild illness in children, until the emergence of the novel hyperinflammatory condition paediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PIMS-TS). PIMS-TS is thought to be a post-SARS-CoV-2... |
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Therapeutic and prognostic role of vitamin D for COVID-19 infection: A systematic review and meta-analysis of 43 observational studies
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| Vitamin D modulates the systemic inflammatory response through interaction with immune system. As such, it has a possible protective role against the risk of respiratory tract infections and other diseases. It may be useful in particular, during COVID-19 pandemic. PubMed, the Cochrane Library, and EMBASE were searched ... |
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Exploring the impact of daily food habit and modification of lifestyle for boosting immunity against COVID-19
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| The lockdown crisis due to novel coronavirus (COVID-19) mainly affected people who live under economic despair. Since boosting the immune system against the virus depends on a variety of food intake and lifestyle approaches; hence, it is crucial to know how daily food habits and lifestyle modification protect from path... |
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Effect of giving probiotic supplement Lactobacillus acidophilus La-14 as an immunomodulator to maintain a respiratory system in Mus musculus
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| Background and Objectives: In 2020 the whole world is experiencing a pandemic condition due to infection with the SARS-CoV-2 virus which can cause the COVID-19 disease. This condition results in "Panic Buying", because everyone tries to avoid the spread and transmission of the COVID-19 disease by doing various ways, on... |
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Vulnerability and weaknesses of eating habits of overweight school children as an entry risk for covid-19
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| BACKGROUND: In developing countries, overweight among children becomes an alarming problem and a health concern Obesity is a factor in disease severity of coronavirus disease (COVID-19) having the greatest impact on patients AIM: The aim of this study was to determine the prevalence of overweight in some of the Egyptia... |
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COvid-19 and high-dose VITamin D supplementation TRIAL in high-risk older patients (COVIT-TRIAL): study protocol for a randomized controlled trial
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| BACKGROUND: With the lack of effective therapy, chemoprevention, and vaccination against SARS-CoV-2, focusing on the immediate repurposing of existing drugs gives hope of curbing the COVID-19 pandemic. A recent unbiased genomics-guided tracing of the SARS-CoV-2 targets in human cells identified vitamin D among the thre... |
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Effects of Vitamin D Serum Level on Morbidity and Mortality in Patients with COVID-19: A Systematic Review and Meta-Analysis.
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| PURPOSE It has been shown that low Vitamin D serum concentration is associated with increased pneumonia and viral respiratory infections. Vitamin D is readily available, inexpensive, and easy to administer to subjects infected with COVID-19. If effective in reducing the severity of COVID-19, it could be an important an... |
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Impact of level of vitamin D in the body on the severity of COVID-19 - review of the literature
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| INTRODUCTION: The aim of the study is to present the current state of knowledge on the influence of vitamin D levels on the severity of the course of COVID-19. MATERIAL AND METHODS: The latest available literature was reviewed until October 30, 2020 from the PubMed database. RESULTS: The literature reports that vitamin... |
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Physiological Role and Use of Thyroid Hormone Metabolites - Potential Utility in COVID-19 Patients
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| Thyroxine and triiodothyronine (T3) are classical thyroid hormones and with relatively well-understood actions. In contrast, the physiological role of thyroid hormone metabolites, also circulating in the blood, is less well characterized. These molecules, namely, reverse triiodothyronine, 3,5-diiodothyronine, 3-iodothy... |
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Effects of Vitamin D on COVID-19 Infection and Prognosis: A Systematic Review
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| INTRODUCTION: Vitamin D status is related to risks of influenza and respiratory tract infections. Vitamin D has direct antiviral effects primarily against enveloped viruses, and coronavirus is an enveloped virus. The 2019 coronavirus disease had a high mortality rate and impacted the whole population of the planet, wit... |
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Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 Supplementation on Infectious Diseases
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| With the appearance of new viruses and infectious diseases (ID) such as COVID-19 in 2019, as well as the lack of specific pharmacological tools for the management of patients with severe complications or comorbidities, it is important to search for adjuvant treatments that help improve the prognosis of infectious disea... |
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Vitamin D Inhibits Lipopolysaccharide (LPS)-Induced Inflammation in A549 Cells by Downregulating Inflammatory Cytokines.
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| BACKGROUND Studies have shown that lung inflammation affects lung function, with life-threatening results. Vitamin D may play an important role in inhibiting inflammatory cytokines. Vitamin D deficiency is related to several lung problems, including respiratory distress syndrome, alveolar inflammation, epithelial damag... |
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Importance of functional nutrition components on new Coronavirus disease (COVID-19) and other viral communicable diseases
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| There are no foods to prevent or treat the coronavirus alone;however, it has been proven that a healthy and balanced nutrition is crucial for health, particularly in times when the immune system might need to fight back. The present study provides insights about the properties of bioactive components of foods and herbs... |
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Metabolic and nutritional triggers associated with increased risk of liver complications in SARS-CoV-2
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| Obesity, diabetes, cardiovascular and respiratory diseases, cancer and smoking are risk factors for negative outcomes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can quickly induce severe respiratory failure in 5% of cases. Coronavirus disease-associated liver injury may occur during progress... |
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The oxygen dissociation curve of blood in COVID-19
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| COVID-19 hinders oxygen transport to the consuming tissues by at least two mechanisms: In the injured lung, saturation of hemoglobin is compromised, and in the tissues, an associated anemia reduces the volume of delivered oxygen. For the first problem, increased hemoglobin oxygen affinity [left shift of the oxygen diss... |
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Selenium, a micronutrient can modulate viral diseases including COVID-19
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| Selenium, a micronutrient is reported to play a very important role in fighting bacterial and viral infections Selenium exerts its effects through incorporation into selenoproteins that are crucial for providing antioxidant defense and maintaining redox homeostasis The deficiency of selenium in the diet leads to impair... |
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Impact of Nutrition in the Management of Nutritional Status of Covid-19 Patients
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| The second outbreak of severe acute respiratory syndrome coronavirus (SARS-CoV-2) is of great concern due to its awful mortality and morbidity rate with decreasing nutritional status and poor lifestyle as well as noteworthy food crisis and affected economy of the world. Increasing food prices, food crisis, global hunge... |
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Vitamin D and survival in COVID-19 patients: A quasi-experimental study
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| Vitamin D may be a central biological determinant of COVID-19 outcomes. The objective of this quasi-experimental study was to determine whether bolus vitamin D3 supplementation taken during or just before COVID-19 was effective in improving survival among frail elderly nursing-home residents with COVID-19. Sixty-six re... |
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Vitamin A and D deficiencies in the prognosis of respiratory tract infections: A systematic review with perspectives for COVID-19 and a critical analysis on supplementation (preprint)/ pt
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| OBJECTIVE: Considering the rapid spread of COVID-19, the scientific community has been looking for ways to recognize factors that may interfere with the outcome of viral infection. Despite the lack of studies with the new coronavirus, it is known that adequate serum levels of micronutrients are essential for the organi... |
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Promising Indicators in Probiotic-recommendations in COVID-19 and its Accompanying Diseases
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| Scientific data suggests the possible beneficial role of probiotics in treatments for COVID-19, but the species/strains-specificity and disease-specificity of probiotics need high attention in choosing the appropriate probiotic in diseases, in particularly in the COVID-19. We hope this review will raise awareness of th... |
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Antiviral mouthwashes: possible benefit for COVID-19 with evidence-based approach
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| Background: The outbreak, and pandemic of COVID-19 causing widespread concerns in all health systems of countries. Virus-carrying aerosols can penetrate the healthy human body and lungs, resulting in rapid transmission. For the first time, in this evidence-based article, the effects of different types of mouthwashes to... |
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Food Ingredients and Active Compounds against the Coronavirus Disease (COVID-19) Pandemic: A Comprehensive Review
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| As media reports have noted, the COVID-19 pandemic has accelerated market mainstreaming of immune-boosting food bioactives, supplements, and nutraceuticals. However, most studies reporting on the potential of bioactives against COVID-19 transmission have been uploaded as preprints with little opportunity to revise cont... |
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Vitamin D and Chronic Obstructive Pulmonary Disease
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| Vitamin D is an important regulator of calcium and bone homeostasis. It is also involved in the regulation of different genes and cellular functions, particularly in the context of inflammation, regeneration and immune control. Conversely, vitamin D deficiency which is often found in chronic, infectious and inflammator... |
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Selenium as a bioactive micronutrient in the human diet and its cancer chemopreventive activity
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| This review answers the question of why selenium is such an important trace element in the human diet Daily dietary intake of selenium and its content in various food products is discussed in this paper, as well as the effects of its deficiency and excess in the body Moreover, the biological activity of selenium, which... |
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Pharmaconutrition in the Clinical Management of COVID-19: A Lack of Evidence-Based Research But Clues to Personalized Prescription
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| A scientific interest has emerged to identify pharmaceutical and nutritional strategies in the clinical management of coronavirus disease 2019 (COVID-19). The purpose of this narrative review is to critically assess and discuss pharmaconutrition strategies that, secondary to accepted treatment methods, could be candida... |
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Vitamin D deficiency among patients with COVID-19: case series and recent literature review
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| Background: The world is now challenging the pandemic of COVID-19 infection This is the third and most extensive pandemic Previous studies showed the plausibility of vitamin D prophylaxis and therapy for COVID-19, particularly in settings where hypovitaminosis D is frequent Recent study from Indonesian showed that the ... |
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Impact of Zinc, Glutathione, and Polyphenols as Antioxidants in the Immune Response against SARS-CoV-2
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| SARS-CoV-2, the coronavirus triggering the disease COVID-19, has a catastrophic health and socioeconomic impact at a global scale Three key factors contribute to the pathogenesis of COVID-19: excessive inflammation, immune system depression/inhibition, and a set of proinflammatory cytokines Common to these factors, a c... |
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Understanding the Co-Epidemic of Obesity and COVID-19: Current Evidence, Comparison with Previous Epidemics, Mechanisms, and Preventive and Therapeutic Perspectives
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| PURPOSE OF REVIEW: A growing body of evidence suggests that obesity and increased visceral adiposity are strongly and independently linked to adverse outcomes and death due to COVID-19. This review summarizes current epidemiologic data, highlights pathogenetic mechanisms on the association between excess body weight an... |
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Effective Regulation of Gut Microbiota With Probiotics and Prebiotics May Prevent or Alleviate COVID-19 Through the Gut-Lung Axis
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| Coronavirus disease 2019 (COVID-19) can disrupt the gut microbiota balance, and patients usually have intestinal disorders. The intestine is the largest immune organ of the human body, and gut microbes can affect the immune function of the lungs through the gut-lung axis. Many lines of evidence support the role of bene... |
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Alimentos, Sars-CoV-2 e Covid-19: contato possível, transmissão improvável
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| abstract The struggle against Covid-19 has driven enormous advances in scientific research, but also the dissemination of low-quality information, with little or no scientific basis Unfortunately, food appears recurringly in the mainstream media as a possible disseminator of the disease, raising concerns in consumers, ... |
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Does Evidence Exist to Blunt Inflammatory Response by Nutraceutical Supplementation during COVID-19 Pandemic? An Overview of Systematic Reviews of Vitamin D, Vitamin C, Melatonin, and Zinc
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| More than one year has passed since the first cases of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS)-CoV-2 coronavirus were reported in Wuhan (China), rapidly evolving into a global pandemic. This infectious disease has become a major public health challenge in the world. Unfort... |
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Vitamin d supplementation for COVID-19: Is it necessary?
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| The development of the COVID-19 vaccine is currently quite encouraging amid increasing mortality and transmission of the COVID-19 virus in various countries. Apart from vaccination the government also needs to consider vitamin D supplementation policies because it has a significant role in boosting the immune system. |
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COVID-19: Role of Nutrition and Supplementation
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| At the end of 2019, a new coronavirus (COVID-19) appeared on the world scene, which mainly affects the respiratory system, causing pneumonia and multi-organ failure, and, although it starts with common symptoms such as shortness of breath and fever, in about 2-3% of cases it leads to death. Unfortunately, to date, no s... |
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Obesity, Hypovitaminosis D, and COVID-19: the Bermuda Triangle in Public Health
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| PURPOSE OF REVIEW: The COVID-19 pandemic has challenged public health to a significant extent by markedly increasing morbidity and mortality. Evidence suggests that obesity and hypovitaminosis D constitute important risk factors for SARS-CoV-2 infection, severity of disease, and poor outcomes. Due to their high prevale... |
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Nutritional status of patients with COVID-19
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| The relationship between immunity and nutrition is well known and its role in coronavirus disease 2019 (COVID-19) is also being paid great attention. However, the nutritional status of COVID-19 patients is unknown. Vitamin B1, B6, B12, vitamin D (25-hydroxyvitamin D), folate, selenium, and zinc levels were measured in ... |
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Extracellular Oxidative Stress Markers in COVID-19 Patients with Diabetes as Co-Morbidity
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| COVID-19 patients have a higher risk of developing inflammatory responses associated with serious and even fatal respiratory diseases. The role of oxidative stress in exacerbating manifestations in COVID-19 pathogenesis is under-reported.This study aimed touseserum levels of superoxide dismutase (SOD3) and glutathione-... |
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The Influence of Nutritional Supplementation for Iron Deficiency Anemia on Pregnancies Associated with SARS-CoV-2 Infection
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| Anemia is a very common occurrence during pregnancy, with important variations during each trimester. Anemia was also considered as a risk factor for severity and negative outcomes in patients with SARS-CoV-2 infection. As the COVID-19 pandemic poses a significant threat for pregnant women in terms of infection risk an... |
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Tobacco Products and the Risks of SARS-CoV-2 Infection and COVID-19
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| IMPLICATIONS: This commentary addresses the state of the evidence on tobacco products, nicotine, and COVID-19. The evidence of the effects of smoking on respiratory infections and the immune system in general are examined and the current understanding of tobacco products and risk for SARS-CoV-2 infection and the course... |
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Influence of vitamin D status on hospital length of stay and prognosis in hospitalized patients with moderate to severe COVID-19: a multicenter prospective cohort study
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| BACKGROUND: Vitamin D acts as a mediator in the immune system regulating antiviral mechanisms and inflammatory processes. Vitamin D insufficiency has been suggested as a potential risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, although its impact on the prognosis of hospitalized... |
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Vitamin C for COVID-19: A living systematic review./ Vitamin C for COVID-19: A living systematic review
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| Objective: This living systematic review aims to provide a timely, rigorous, and continuously updated summary of the available evidence on the role of vitamin C in treating patients with COVID-19. Data sources: We conducted searches in PubMed/MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), gr... |
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Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?
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| BACKGROUND: Women with polycystic ovary syndrome (PCOS) often have vitamin D deficiency, a known risk factor for severe COVID-19 disease. Alveolar macrophage-derived cytokines contribute to the inflammation underlying pulmonary disease in COVID-19. We sought to determine if basal macrophage activation, as a risk factor... |
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Likely positive effect of alpha-linolenic acid supplementation on the lung and the negative effect of it on the adipose tissue of COVID-19 patients
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| Purpose: This paper aims to describe the likely positive effects of alpha-linolenic acid supplementation on the lung and the negative effects of it on the adipose tissue of COVID-19 patients Design/methodology/approach: This paper focuses on investigating the effects of alpha-linolenic (ALA) on the respiratory system a... |
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Could Vitamins Help in the Fight Against COVID-19?
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| There are limited proven therapeutic options for the prevention and treatment of COVID-19. The role of vitamin and mineral supplementation or "immunonutrition" has previously been explored in a number of clinical trials in intensive care settings, and there are several hypotheses to support their routine use. The aim o... |
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The vitamin D for COVID-19 (VIVID) trial: A pragmatic cluster-randomized design
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| Objectives To determine the effect of vitamin D supplementation on disease progression and post-exposure prophylaxis for COVID-19 infection. We hypothesize that high-dose vitamin D3 supplementation will reduce risk of hospitalization/death among those with recently diagnosed COVID-19 infection and will reduce risk of C... |
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Vitamin D Clinical Pharmacology: Relevance to COVID-19 Pathogenesis
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Metabolic Support for Elderly, Severe COVID-19 Patients With Acute Respiratory Failure: A Case Series
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| OBJECTIVES: Severe COVID-19 (SvC19) is a syndrome of acute lung injury, respiratory failure, cytokine storm, distributive shock, multi-system organ failure and high mortality. SvC19 disproportionately impacts the elderly, who are also at risk for micronutrient deficiency. After observing a beneficial response to micron... |
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Relation of Dietary Factors with Infection and Mortality Rates of COVID-19 across the World
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| OBJECTIVE: Poor dietary habits are considered to be the second-leading risk factors for mortality and disability-adjusted life-years (DALYs) in the world. Dietary patterns are different based on cultural, environmental, technological, and economic factors. Nutritional deficiencies of energy, protein, and specific micro... |
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Cannabinoids and COVID-19
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| Since the endocannabinoid system is involved in immune function, the effect of cannabinoid intake on infectious conditions is questioned for several years and is of particular interest in the COVID 19 pandemia Some data suggest that the immunomodulatory effect of cannabinoids may affect the course and severity of SARS-... |
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Chronic systemic low-grade inflammation and modern lifestyle: the dark role of gut microbiota on related diseases with a focus on pandemic COVID-19
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| Inflammation is a physiological, beneficial and auto-limiting response of the host to alarming stimuli. Conversely, a chronic systemic low-grade inflammation (CSLGI), known as a long-time persisting condition, causes organs and host tissues' damage, representing a major risk for chronic diseases. Currently, a worldwide... |
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Why COVID-19 strengthens the case to scale up assault on non-communicable diseases: role of health professionals including physical therapists in mitigating pandemic waves
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| As SARS-CoV-2, the virus responsible for COVID-19, spread globally, the most severely affected sub-populations were the elderly and those with multi-morbidity largely related to non-communicable diseases (NCDs), e g , heart disease, hypertension, type 2 diabetes, obesity NCDs are largely preventable with healthy nutrit... |
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Saudi community care awareness food facts, nutrients, immune system and Covid-19 prevention in Taif City among different age categories
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| AFRICAN DEVELOPMENT Abstract: In December 2019, a new coronavirus was discovered in China, sparking a serious pandemic of human acute respiratory syndrome which spread worldwide at a fast rate Public health knowledge and awareness is required on food facts, nutrients and immune system for coronavirus prevention The stu... |
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Does intestinal dysbiosis contribute to an aberrant inflammatory response to SARS-CoV-2 in frail patients?
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| In few months, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become the main health worldwide problem. Epidemiological studies revealed that population has different vulnerability to SARS-CoV-2: severe outcome of COVID-19, with an increased risk of death, is observed in patients with metabo... |
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Vitamin D-related polymorphisms and vitamin D levels as risk biomarkers of COVID-19 infection severity
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| Background: Vitamin D is a fundamental regulator of host defences by activating genes related to innate and adaptive immunity. Previous research shows a correlation between the levels of vitamin D in patients infected with SARS-CoV-2 and the degree of disease severity. This work investigates the impact of the genetic b... |
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Please summerize the given abstract to a title
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Can Vitamin D and L-Cysteine Co-Supplementation Reduce 25(OH)-Vitamin D Deficiency and the Mortality Associated with COVID-19 in African Americans?
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| Early reports indicate an association between the severity of the COVID-19 infection and the widespread 25-hydroxy vitamin D deficiency known to exist in populations around the world. Vitamin D deficiency is extremely common among African American (AA) communities, where the COVID-19 infection rate is three-fold higher... |
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Please summerize the given abstract to a title
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The potential role of inhaled nitric oxide for postexposure chemoprophylaxis of COVID-19
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| Background Several vaccines have been fast-tracked in an attempt to decrease the morbidity and mortality of COVID-19. However, post-exposure prophylaxis has been overlooked in battling COVID-19. Main text Inhaled nitric oxide is a potential tool in post-exposure prophylaxis of COVID-19. It decreases cytosolic calcium l... |
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Please summerize the given abstract to a title
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Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial.
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| Importance The efficacy of vitamin D3 supplementation in coronavirus disease 2019 (COVID-19) remains unclear. Objective To investigate the effect of a single high dose of vitamin D3 on hospital length of stay in patients with COVID-19. Design, Setting, and Participants This was a multicenter, double-blind, randomized, ... |
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Please summerize the given abstract to a title
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Effect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D Levels: The VDKA Randomized Clinical Trial
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| Importance: Severe asthma exacerbations cause significant morbidity and costs. Whether vitamin D3 supplementation reduces severe childhood asthma exacerbations is unclear. Objective: To determine whether vitamin D3 supplementation improves the time to a severe exacerbation in children with asthma and low vitamin D leve... |
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Can COVID-19 be a risk for cachexia for patients during intensive care? Narrative review and nutritional recommendations
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| [Figure: see text] |
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Please summerize the given abstract to a title
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Vitamin D and Its Potential Benefit for the COVID-19 Pandemic
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| Vitamin D is known not only for its importance for bone health but also for its biologic activities on many other organ systems. This is due to the presence of the vitamin D receptor in various types of cells and tissues, including the skin, skeletal muscle, adipose tissue, endocrine pancreas, immune cells, and blood v... |
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Human Intestinal Microbiome and the Immune System: The Role of Probiotics in Shaping an Immune System Unsusceptible to COVID-19 Infection
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| Today, the human gastrointestinal microbiota (HGM) is seen as an organ that orchestrates the activity of all other organs and systems (namely the brain) and one that plays a major role in maintaining homeostasis of the host organism. A remarkable ability of the HGM as a key player in the development of a normal immune ... |
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[The role of supplying population with vitamin D in conditions of COVID-19 pandemic: foreign publications review].
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| The overview of scientific information concerning actual characteristics of population's supply with vitamin D and its role in case of risk of development of infectious diseases and COVID-19 is presented. The analysis established that vitamin D deficiency contributes both to higher risk of susceptibility to infectious ... |
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Please summerize the given abstract to a title
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Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID‐19
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| In this study, we investigated the role and relationship between the cytokine profile and protective vitamin D by measuring their serum levels in COVID‐19 intensive care unit patients with severe illnesses. A total of 74 patients were included in our study. Patients were divided into two groups. Patients in the COVID‐1... |
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### Response:
Hypozincemia in the early stage of COVID-19 is associated with an increased risk of severe COVID-19
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| BACKGROUND & AIMS: Nutritional predisposition to severe coronavirus disease 2019 (COVID-19) remains unclear. Zinc deficiency could be critical since it is associated with a higher susceptibility to infections. We evaluated the prevalence of hypozincemia in the early stage of COVID-19, its association with risk factors ... |
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### Response:
Tea Bioactive Modulate Innate Immunity: In Perception to COVID-19 Pandemic
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| Innate immunity impairment led to disruption in cascade of signaling pathways upregulating pro-inflammatory cytokines, diminish interferons, depleted natural killer cells and activate reactive oxygen species production. These conditions severely affected body's ability to fight against infectious diseases and also play... |
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Please summerize the given abstract to a title
### Response:
Foreword - The importance of a healthy microbiota in the era of COVID-19.
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| At the start of 2020 we were thrilled to have reached 10 years of Beneficial Microbes! Little did we know that soon after Europe and the rest of the world (with Asia already earlier) would be in lock-down due to COVID-19. It has been a strange year. And now, at the start of 2021, the excitement of having a vaccine is t... |
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Please summerize the given abstract to a title
### Response:
Vitamin D Levels in COVID-19 Outpatients from Western Mexico: Clinical Correlation and Effect of Its Supplementation
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| Background: The immunomodulatory effects of vitamin D are known to be beneficial in viral infections; it is also known that its deficiency is associated with a prognosis more critical of Coronavirus Disease 2019. This study aimed to determine baseline vitamin D serum concentrations and the effects of its supplementatio... |
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Linking COVID-19 and Parkinson's disease: Targeting the role of Vitamin-D
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| COVID-19 pandemic has a major effect on world health, particularly on individuals suffering from severe diseases or old aged persons. Various case studies revealed that COVID-19 might increase the progression of Parkinson's disease (PD). Coxsackievirus, dengue virus Epstein-Barr virus, hepatitis C virus, Japanese encep... |
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### Response:
Coronavirus disease-19 Pandemic and Vitamin D: So Much for so Little?
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| Apropos of Kershenobich's interesting editorial titled: Dilemmas of a physician in times of coronavirus disease (COVID-19), in which he cites multiple drugs under study for COVID-19, many of which we now know to be ineffective, I have noticed the absence of Vitamin D1. It is well known that levels of regulatory T-lymph... |
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Please summerize the given abstract to a title
### Response:
Interacción entre la edad y el déficit de vitamina D en la COVID-19 grave./ Interaction between age and vitamin D deficiency in severe COVID-19 infection
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| BACKGROUND: coronavirus disease 2019 (COVID-19) can induce an exaggerated inflammatory response. Vitamin D is a key modulator of the immune system. We hypothesized that vitamin D deficiency (VDD) could increase the risk of developing severe COVID-19 infection. METHODS: patients with confirmed COVID-19 seen at the emerg... |
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Please summerize the given abstract to a title
### Response:
Knowledge and health behavior about vitamin d during epidemic covid-19 among female university students
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| Background:Vitamin D deficiency it considers a global health problem and a significantly linked with skeletal and non-skeletal problems. Prevention can be kept by sun exposure or supplementation and to lower extent by dietary intake. Objective: to assessedknowledge and health behavior regarding the vitamin Dduring epid... |
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### Response:
The Essential Role of Vitamin D in the Biosynthesis of Endogenous Antimicrobial Peptides May Explain Why Deficiency Increases Mortality Risk in COVID-19 Infections
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| Abstract: A primary action of vitamin D is regulation of gene transcription. Many cell types possess genes that make antimicrobial peptides (AMPS) (endogenous antibiotics), recently discovered to be regulated by vitamin D. Two examples are cathelicidin and beta defensins, both bioactive against many different bacteria,... |
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Please summerize the given abstract to a title
### Response:
Observational study on the benefit of a nutritional supplement, supporting immune function and energy metabolism, on chronic fatigue associated with the SARS-CoV-2 post-infection progress
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| Background & Aims Recent studies have verified that the SARS-CoV-2 infection (from December 2019 has affected 123 million people throughout the world and more than 3 million people in Italy), can have medium-term and long-term effects, collectively referred to as "post-Covid syndrome" or "long-Covid” characterized by c... |
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Please summerize the given abstract to a title
### Response:
Effects of Zinc Supplementation on Metabolic Status in Patients with Metabolic Syndrome
### Response:
| Being a micronutrient, zinc involves in numerous biochemical reactions as a principle component or catalyzing enzymes for proper propagation of enzymatic function. Metabolic syndrome (MS) has been increasingly reported to be associated with derangement of the intrinsic physiological functions including suppression of m... |
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Please summerize the given abstract to a title
### Response:
Dietary Supplements during COVID-19 Outbreak. Results of Google Trends Analysis Supported by PLifeCOVID-19 Online Studies
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| The use of dietary supplements (DSs) has been steadily increasing all over the world and additionally, the sales of DSs have dynamical increased in the wake of coronavirus disease 2019 (COVID-19) in most of the countries We investigated DSs phenomenon in 2020 through (1) exploration of Google searches worldwide and in ... |
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Please summerize the given abstract to a title
### Response:
Nutritional interventions in older people with COVID-19: an overview of the evidence
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| Older people are a high-risk group for coronavirus disease 2019 (COVID-19) because of a range of factors, including age-related changes in anatomical pulmonary and muscle function, decreased immunity and increased inflammation. These factors partly explain why older people with COVID-19 experience more severe symptoms ... |
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### Response:
Is Nano-Biofortification the Right Approach for Malnutrition in the Era of COVID-19 and Climate change?
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| HUMAN health may depend on the environment and its compartments, which may include climatic factors. These climatic factors and their changes might impact on human health particularly the outbreak of pandemics like COVID-19. The combined stress resulted from climate changes and COVID-19 could be noticed in several coun... |
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Please summerize the given abstract to a title
### Response:
Effect of a Single High-Dose Vitamin D(3) on the Length of Hospital Stay of Severely 25-Hydroxyvitamin D-Deficient Patients with COVID-19
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| OBJECTIVES: In this ancillary analysis of a multicenter, double-blinded, randomized, placebo-controlled trial, we investigated the effect of a single high dose of vitamin D(3) on the length of hospital stay of patients with severe 25-hydroxyvitamin D deficiency and COVID-19. METHODS: The primary outcome was length of h... |
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Please summerize the given abstract to a title
### Response:
Can erythrocytes behavior in microcirculation help the understanding the physiopathology and improve prevention and treatment for covid-19?
### Response:
| Low plasma estrogens, vitamin D deficiency, obesity, diabetes, cardiovascular diseases, thromboembolism, and impaired microcirculation are linked to the severity of covid-19. Studies have suggested that these comorbidities also are related to erythrocyte factors linked to increased blood viscosity in microcirculation s... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Latitude Dependence of the COVID-19 Mortality Rate—A Possible Relationship to Vitamin D Deficiency?
### Response:
| The latitude dependence of death rates due to COVID-19 infection suggests a possible relationship to vitamin D deficiency This relationship is made stronger wh |
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Please summerize the given abstract to a title
### Response:
Hypocalcemia in COVID-19 is associated with low vitamin D levels and impaired compensatory PTH response
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| BACKGROUND: Hypocalcemia has been identified as a major distinctive feature of COVID-19, predicting poor clinical outcomes. Among the mechanisms underlying this biochemical finding, high prevalence of vitamin D (VD) deficiency in COVID-19 patients reported so far in several studies was advocated. However, robust data i... |
### Instruction:
Please summerize the given abstract to a title
### Response:
Hyperferritinemia in patients with COVID-19: An opportunity for iron chelation?
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| Studies from China on COVID-19 revealed that nonsurvivors had cytokine storm with high IL-6 and hyperferritinemia. Iron liberated from necrotic cells may catalyze free radical production and amplify lipid peroxidation causing membrane dysfunction and multiorgan failure. Consequently, iron chelators have been successful... |
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