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CURE FOR PNEUMONIA Dear DR, please i have a friend that has the above illness..I want to find out...since i want to marry her...is it an infectious illness,,and can it be totally cured. And how can i help her to get this cured..Please i really need your reply urgently
Viral pneumonias may be treated with anti-viral med... | 47 | [
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Rubella My grandson (4 yrs old) has contracted Rubella. I know for sure he has had at least one of the vaccines. They are living in Mexico right now. Should we be worried?
The measles-mumps-rubella (MMR) vaccine, usually given to children in the United States twice before they reach school age, is highly effective i... | 225 | [
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what the treatment for bronchitis
Most cases of acute bronchitis get better without treatment, usually within a couple of weeks. Because most cases of bronchitis are caused by viral infections, antibiotics aren't effective. If doctors suspect that the infection is bacterial, they may prescribe an antibiotic. Doctors ma... | 302 | [
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what the treatment for bronchitis
Most cases of acute bronchitis get better without treatment, usually within a week. Cases of bronchitis that are caused by viral infections do not need antibiotics. If doctors suspect that the infection is bacterial, they may prescribe an antibiotic. Sometimes, corticosteroid medicine ... | 305 | [
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CURE FOR PNEUMONIA Dear DR, please i have a friend that has the above illness..I want to find out...since i want to marry her...is it an infectious illness,,and can it be totally cured. And how can i help her to get this cured..Please i really need your reply urgently
Medicines that treat viruses may work against some ... | 599 | [
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Rubella My grandson (4 yrs old) has contracted Rubella. I know for sure he has had at least one of the vaccines. They are living in Mexico right now. Should we be worried?
The measles-mumps-rubella (MMR) vaccine, usually given to children in the United States twice before they reach school age, is highly effective i... | 777 | [
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CURE FOR PNEUMONIA Dear DR, please i have a friend that has the above illness..I want to find out...since i want to marry her...is it an infectious illness,,and can it be totally cured. And how can i help her to get this cured..Please i really need your reply urgently
Viral pneumonias may be treated with anti-viral med... | 1,151 | [
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Rubella My grandson (4 yrs old) has contracted Rubella. I know for sure he has had at least one of the vaccines. They are living in Mexico right now. Should we be worried?
The measles-mumps-rubella (MMR) vaccine, usually given to children in the United States twice before they reach school age, is highly effective i... | 1,329 | [
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CURE FOR PNEUMONIA Dear DR, please i have a friend that has the above illness..I want to find out...since i want to marry her...is it an infectious illness,,and can it be totally cured. And how can i help her to get this cured..Please i really need your reply urgently
Medicines that treat viruses may work against some ... | 1,703 | [
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Rubella My grandson (4 yrs old) has contracted Rubella. I know for sure he has had at least one of the vaccines. They are living in Mexico right now. Should we be worried?
The measles-mumps-rubella (MMR) vaccine, usually given to children in the United States twice before they reach school age, is highly effective i... | 1,881 | [
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Please answer the letter of option truthfully
C
Q:There are 57 serotypes of adenovirus currently recognised. Which has the most important clinical impact??
A:Diarrhoea;B:Eye infections;C:Respiratory tract infections;D:Haemorrhagic cystitis
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Answer this question truthfully
Respiratory syncytial virus (RSV) is the most common cause of atypical pneumonia in infants. RSV is a highly contagious virus that affects the respiratory tract, particularly in young children and infants. Symptoms of RSV can range from mild cold-like symptoms to more severe respiratory ... | 8,592 | [
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Answer this question truthfully
Palivizumab is a monoclonal antibody that can be used as prophylaxis against respiratory syncytial virus (RSV) in high-risk infants who are under the age of 2. RSV is a common respiratory virus that can cause serious illness, especially in premature infants and those with underlying heal... | 8,885 | [
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Answer this question truthfully
Influenza virus is a respiratory virus that can increase the risk of developing superimposed bacterial pneumonia, such as infections caused by S. aureus and H. influenzae. Influenza infection can damage the respiratory tract and weaken the immune system, making it easier for bacteria to ... | 9,381 | [
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Answer this question truthfully
Atypical pneumonia is a type of pneumonia that is caused by a variety of pathogens, including viruses such as influenza. Influenza is a common viral cause of atypical pneumonia in the elderly, who may be more susceptible to severe illness and complications from influenza infection. Sympt... | 9,382 | [
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Answer this question truthfully
Croup is a viral respiratory infection that primarily affects young children. It is caused by the parainfluenzavirus and is characterized by a seal-like barking cough, hoarseness, and difficulty breathing. Croup typically starts with symptoms of a common cold, such as a runny nose and fe... | 9,955 | [
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Answer this question truthfully
Hemagglutinin, F (fusion) protein, and Neuraminidase are the virulence factors associated with parainfluenza (croup).
What are the virulence factors associated with parainfluenza (croup)?
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Answer this question truthfully
The viral virulence factor associated with RSV is the F (fusion) protein.
What is the viral virulence factor associated with RSV?
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Answer this question truthfully
RSV (respiratory syncytial virus) belongs to the Paramyxovirus family and has a negative sense RNA genome.
What is the viral classification of RSV (respiratory syncytial virus)?
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Answer this question truthfully
Parainfluenza is a type of Paramyxovirus.
What is the viral classification of parainfluenza, which is commonly associated with croup?
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Answer this question truthfully
Human metapneumovirus belongs to the Paramyxovirus family.
What is the viral classification of human metapneumovirus?
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Answer this question truthfully
The type of influenza vaccine that is administered via intranasal spray is the live attenuated vaccine. This vaccine contains weakened live viruses that can still replicate in the nasal passages but are unable to cause influenza in healthy individuals. The live attenuated influenza vacci... | 12,103 | [
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Answer this question truthfully
The measles virus belongs to the family Paramyxoviridae.
Paramyxoviridae is a family of RNA viruses that includes several important human pathogens, including the measles virus, as well as the mumps virus, respiratory syncytial virus, and parainfluenza viruses.
The measles virus is a h... | 12,482 | [
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The influenza virus belongs to the family Orthomyxoviridae.
Orthomyxoviridae is a family of RNA viruses that includes several important human pathogens, including the influenza virus. There are three types of influenza viruses: A, B, and C. Influenza A and B viruses are responsible for ... | 12,483 | [
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Answer this question truthfully
The first three doses of the pneumococcal conjugate vaccine (PCV13) are typically administered at 2 months, 4 months, and 6 months of age.
What is the typical schedule for administering the first three doses of the pneumococcal conjugate vaccine (PCV13)?
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Answer this question truthfully
The first three doses of the inactivated poliovirus vaccine (IPV) are typically administered at 2 months, 4 months, and 6 months of age.
What is the typical schedule for administering the first three doses of the inactivated poliovirus vaccine (IPV)?
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Answer this question truthfully
Rhinovirus is considered the most common cause of the common cold.
Which virus is considered the most common cause of the common cold?
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Answer this question truthfully
The recommended treatment for respiratory syncytial virus (RSV) in adults is ribavirin.
What is the recommended treatment for respiratory syncytial virus (RSV) in adults?
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The typical treatment for bronchiolitis is supportive care, which may include the administration of oxygen and intravenous fluids (IVF). Bronchiolitis is a common respiratory illness that affects infants and young children, and is usually caused by a viral infection. While there is no sp... | 15,255 | [
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Rhinovirus is primarily transmitted through respiratory routes, such as when an infected person coughs or sneezes. The virus can also be transmitted through contact with contaminated surfaces, known as fomites, such as doorknobs, keyboards, or phones. When a person touches a contaminated... | 15,419 | [
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Paramyxoviruses are primarily transmitted through respiratory droplets. When an infected person coughs, sneezes, or talks, they release small droplets containing the virus into the air. These droplets can be inhaled by others in close proximity, leading to infection. Paramyxoviruses can ... | 15,421 | [
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Influenza is primarily transmitted through respiratory droplets. When an infected person coughs, sneezes, or talks, they release small droplets containing the virus into the air. These droplets can be inhaled by others in close proximity, leading to infection. Influenza can also be trans... | 15,423 | [
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-0.74462890625,
-0.10479736328125,
-0.66259765625,
-0.737792968... | 53 |
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The recommended empirical treatment for patients with community-acquired pneumonia in an inpatient setting is a respiratory fluoroquinolone, such as moxifloxacin.
Community-acquired pneumonia (CAP) is a common infection that affects the lungs and is acquired outside of a hospital or hea... | 15,710 | [
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-1.015625,
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The recommended management approach for a child who presents with a runny nose, cough, and pharyngeal vesicles is reassurance and observation. These symptoms are commonly seen in viral illnesses, such as the common cold or flu, and are usually self-limited. Treatment is typically support... | 16,094 | [
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-0.1728515625,
-0.84228515625,
-0.047149658203125,
-0.415283203125... | 53 |
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The most common trigger of acute exacerbation in patients with chronic obstructive pulmonary disease (COPD) is an upper respiratory infection (URI). Acute exacerbation of COPD refers to a sudden worsening of symptoms such as cough, shortness of breath, and wheezing, which can lead to hos... | 16,274 | [
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-0.59326171875,
0.0122833251953125,
-0.56787109375,
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Respiratory syncytial virus (RSV) is the most common primary agent causing bronchiolitis. RSV is a highly contagious virus that affects the respiratory tract, particularly in infants and young children. Symptoms of RSV infection may include coughing, wheezing, difficulty breathing, fever... | 16,325 | [
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-1.304... | 53 |
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The most common predisposing factor for acute bacterial sinusitis is a viral upper respiratory infection (URI), which can cause inflammation and swelling of the nasal passages and sinuses, making it easier for bacteria to cause infection. Acute bacterial sinusitis is a common condition t... | 16,330 | [
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The most common complication associated with influenza is secondary bacterial pneumonia. Influenza, commonly known as the flu, is a viral respiratory illness that can cause various symptoms, such as fever, cough, and body aches. In some cases, influenza can lead to complications, such as... | 16,427 | [
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Rhinovirus is the most common cause of the common cold. It is a highly contagious virus that is transmitted through respiratory droplets when an infected person coughs or sneezes. Rhinovirus can cause a range of symptoms, including nasal congestion, runny nose, sore throat, cough, and he... | 16,444 | [
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The most common cause of pneumonia in infants is respiratory syncytial virus (RSV), which is a highly contagious virus that can cause respiratory infections ranging from mild cold-like symptoms to severe lower respiratory tract infections such as pneumonia. Other potential causes of pneu... | 16,474 | [
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The most common cause of laryngotracheobronchitis (croup) is the parainfluenza virus.
Among the possible causes of laryngotracheobronchitis (croup), which one is the most prevalent?
| 16,494 | [
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... | 53 |
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The most common cause of laryngotracheitis (croup) is the parainfluenza virus.
Among the possible causes of laryngotracheitis (croup), which one is the most prevalent?
| 16,495 | [
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Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in infants.
Among infants, what is the primary cause of bronchiolitis?
| 16,560 | [
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Influenza is likely to be diagnosed in a patient who presents during the winter with sudden onset of high-grade fever, severe myalgias, and headache, with no abnormal lung sounds or lymphadenopathy detected on physical examination. Influenza is a viral respiratory illness that typically ... | 17,302 | [
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The likely diagnosis is community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection, which is a type of bacterial pneumonia that can occur in otherwise healthy individuals who have been exposed to MRSA in the community. CA-MRSA pneumonia often presents with a sudde... | 17,401 | [
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0.1541748046875,
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The likely diagnosis is acute bacterial rhinosinusitis, which is a bacterial infection of the sinuses that can occur after a viral upper respiratory infection (URI). The symptoms of acute bacterial rhinosinusitis may include nasal congestion, facial pain or pressure, headache, cough, fat... | 17,419 | [
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0.2783203125,
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-0.818359375,... | 53 |
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Subacute sclerosing panencephalitis (SSPE) is a potential CNS complication that can arise from measles (rubeola) infection.
What is the potential CNS complication that can arise from measles (rubeola) infection?
| 19,594 | [
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-0.723632... | 53 |
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The three most common viral etiologies of acute bronchitis are influenza A/B, parainfluenza, and adenovirus.
Which are the three most common viral etiologies of acute bronchitis?
| 19,995 | [
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Bronchiolitis is a common respiratory infection that affects young children, especially those under the age of two. While most cases of bronchiolitis are mild and self-limited, some children may develop complications that require hospitalization. Two potential complications of bronchioli... | 20,140 | [
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One way to distinguish between viral and bacterial rhinosinusitis in patients with mild symptoms is by assessing whether the patient is afebrile and whether their symptoms improve within 10 days. Viral rhinosinusitis is more likely to occur in patients who are afebrile and have mild symp... | 20,555 | [
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Viral pneumonia can damage the mucociliary escalator, which is a mechanism in the respiratory tract that helps to clear mucus and bacteria out of the lungs. This damage can make it easier for bacteria to colonize the lungs and cause a secondary bacterial pneumonia. In other words, viral ... | 20,556 | [
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0.1072998046875,
-0.392578125,
-1.00878... | 53 |
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SSPE (subacute sclerosing panencephalitis) can be seen 5-15 years after infection with measles (rubeola).
What viral infection can lead to SSPE (subacute sclerosing panencephalitis) if contracted?
| 24,444 | [
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0.129150390625,
-0.857421875,
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... | 53 |
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Children who are exposed to secondhand smoke are at an increased risk of respiratory tract illnesses, most significantly otitis media and asthma.
What are the respiratory tract illnesses that children are at an increased risk of due to secondhand smoke exposure?
| 24,891 | [
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RSV (respiratory syncytial virus) is typically seen in children under 6 months of age.
In what age group is RSV (respiratory syncytial virus) typically seen in children?
| 25,085 | [
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... | 53 |
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Ribavirin is a medication that is commonly used to treat respiratory syncytial virus (RSV) infection in adult patients. RSV is a common respiratory virus that can cause serious illness, particularly in young children, older adults, and those with weakened immune systems. Ribavirin is an ... | 25,214 | [
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-1.2646484... | 53 |
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Rhinovirus grows best at a temperature of 33°C.
What is the optimal temperature for the growth of Rhinovirus?
| 25,225 | [
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0.016693115234375,
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-0.810546875,
-0.9819335937... | 53 |
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Prevalence is similar to incidence for short duration diseases such as the common cold. Prevalence refers to the total number of cases of a disease in a population at a given time, while incidence refers to the number of new cases of a disease that develop during a specific period of tim... | 25,982 | [
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-0.698730... | 53 |
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Paramyxoviruses are a family of RNA viruses that can cause a range of diseases in humans and animals, including measles, mumps, and respiratory infections. These viruses contain surface F (fusion) proteins that allow them to enter host cells and replicate. Once inside respiratory epithel... | 27,087 | [
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-1.3125,
-0... | 53 |
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Palivizumab is used as prophylaxis for respiratory syncytial virus (RSV) pneumonia in premature infants. RSV is a common respiratory virus that can cause serious illness in young children, especially premature infants with underdeveloped lungs. Palivizumab is a monoclonal antibody that c... | 27,155 | [
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0.44091796875,
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-1... | 53 |
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Palivizumab is indicated for respiratory syncytial virus (RSV) prophylaxis in high-risk infants, and works by binding RSV Fusion protein. RSV is a common respiratory virus that can cause serious illness in young children, especially premature infants with underdeveloped lungs. Palivizuma... | 27,156 | [
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Palivizumab is a monoclonal antibody that targets the fusion (F) protein of respiratory syncytial virus (RSV). RSV is a common respiratory virus that can cause serious illness in young children, especially premature infants with underdeveloped lungs. The F protein is a key component of t... | 27,157 | [
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... | 53 |
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The appropriateness of outpatient therapy for patients with respiratory illness can be determined by calculating their CURB-65 score. CURB-65 is a tool used to assess the severity of community-acquired pneumonia and to guide treatment decisions. It takes into account five factors: confus... | 27,267 | [
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0.139404296875,
-1.09375,
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... | 53 |
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Immunodeficient patients should avoid the administration of MMRV and influenza (intranasal) vaccines due to contraindications, as their weakened immune systems may not be able to mount an effective response to the vaccine and may be at risk of developing severe side effects.
Who should a... | 28,663 | [
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Infants age < 2 months with bronchiolitis are at high risk of developing apnea and/or respiratory failure.
What are some potential complications that infants under 2 months old with bronchiolitis are at high risk of developing?
| 30,416 | [
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In treating patients with RSV, Ribavirin is preferred in adults, while palivizumab is preferred in children.
What is the preferred treatment for patients with RSV in adults versus children?
| 30,655 | [
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Ribavirin is a medication that is commonly used to treat viral infections, including hepatitis C and respiratory syncytial virus (RSV). In addition to hepatitis C, ribavirin is classically used to treat RSV, which is a common cause of respiratory illness in young children and older adult... | 31,365 | [
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Subacute sclerosing panencephalitis typically presents years after a measles infection. This is a rare and serious complication of measles that occurs when the virus remains dormant in the brain for an extended period of time before causing neurological symptoms. While the exact time fra... | 31,986 | [
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Influenza is typically categorized into three different strains: A, B, and C. Influenza A is the most common and can cause severe illness and pandemics, while Influenza B is less severe and usually only causes local outbreaks. Influenza C is less common and generally causes mild respirat... | 32,015 | [
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The recommended course of action for a child presenting with these symptoms is reassurance and supportive care, as they are likely experiencing a viral cold. Viral colds are common in children and are typically caused by a viral infection. The symptoms may include a runny nose, congestio... | 36,568 | [
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The condition that is suggested by a child under 2 years old who has recently had a viral upper respiratory infection and is experiencing wheezing or difficulty breathing during the winter months is bronchiolitis. Bronchiolitis is a common respiratory illness in young children, especiall... | 36,575 | [
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Bronchiolitis should be suspected in a child under 2 years old who presents with initial upper respiratory infection symptoms such as fever and stuffy nose, followed by wheezing and cough during the winter season.
What condition should be suspected in a child under 2 years old who presen... | 39,761 | [
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Depending upon which virus is causing the HFRS, death occurs in less than 1% to as many as 15% of patients. Fatality ranges from 5-15% for HFRS caused by Hantaan virus, and it is less than 1% for disease caused by Puumala virus.
Is HFRS ever fatal?
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The incubation period is 2–5 days (range: 1–10 days). Affected anatomic sites include the mucous membrane of the upper respiratory tract (nose, pharynx, tonsils, larynx, and trachea respiratory diphtheria), skin (cutaneous diphtheria), or rarely, mucous membranes at other sites (eye, ear... | 40,961 | [
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The most important risk factor is age. The infection occurs most often in children under age 10, but can be seen in adolescents and occasionally adults. The outbreaks occur most often in the summer and early fall.
Who is at highest risk for Hand-foot-and-mouth disease ?
| 41,073 | [
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Common Symptoms
Fever Rash Cough Runny Nose Conjunctivitis (pink eye)
Serious Symptoms/Complications
Diarrhea Ear infections Pneumonia Encephalitis Seizures Death
Approximately 20% of reported measles cases experience one or more complications. These complications are more common among c... | 41,206 | [
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Measles is spread by contact with an infected person, through coughing and sneezing (highly contagious). The disease is highly contagious, and can be transmitted from 4 days prior to the onset of the rash to 4 days after the onset. If one person has it, 90% of their susceptible close con... | 41,208 | [
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Acute bronchitis can be caused by contagious pathogens. Acute bronchitis generally follows a viral respiratory infection. Typical viruses include respiratory syncytial virus, rhinovirus, influenza, and others. At first, it affects your nose, sinuses, and throat and then spreads to the lu... | 41,504 | [
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Cold symptoms usually occur within 2-3 days after you came in contact with the virus, although it could take up to a week. Symptoms mostly affect the nose.
The most common cold symptoms are as followings:
Nasal congestion Runny nose Scratchy throat Sneezing
Adults and older children with... | 41,522 | [
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It is called “ common cold ” for good reason. There are over one billion colds in the United States each year. You and your children will probably have colds more than any other types of illness. Colds are the most common reason that children miss school and parents miss work. Parents of... | 41,523 | [
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Common cold can effect people of all age, gender, and ethnic group.
Who is at highest risk for Acute viral nasopharyngitis ?
| 41,526 | [
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Symptoms of avian influenza in humans have ranged from typical human influenza - like symptoms (e.g., fever, cough, sore throat, and muscle aches) to eye infections, pneumonia, severe respiratory diseases (such as acute respiratory distress), and other severe and life-threatening complic... | 41,709 | [
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Of the human cases associated with the ongoing H5N1 outbreaks in poultry and wild birds in Asia and parts of Europe, the Near East and Africa, more than half of those people reported infected with the virus have died. Most cases have occurred in previously healthy children and young adul... | 41,713 | [
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Bronchiolitis usually affects children under the age of 2, with a peak age of 3 - 6 months. It is a common, and sometimes severe illness. Respiratory syncytial virus (RSV) is the most common cause. Other viruses that can cause bronchiolitis include:
Adenovirus Influenza Parainfluenza
The... | 41,818 | [
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Usually, the symptoms get better within a week, and breathing difficulty usually improves by the third day. The mortality rate is less than 1%.
What to expect if I have Bronchiolitis (Outlook/Prognosis)?
| 41,820 | [
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Cold symptoms usually occur within 2-3 days after you came in contact with the virus, although it could take up to a week. Symptoms mostly affect the nose.
The most common cold symptoms are as followings:
Nasal congestion Runny nose Scratchy throat Sneezing
Adults and older children with... | 42,022 | [
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-0.92041... | 53 |
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It is called “ common cold ” for good reason. There are over one billion colds in the United States each year. You and your children will probably have colds more than any other types of illness. Colds are the most common reason that children miss school and parents miss work. Parents of... | 42,023 | [
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Viral croup is the most common. Other possible causes include bacteria, allergies, and inhaled irritants. Acid reflux from the stomach can trigger croup. Viral croup is usually caused by human parainfluenza virus, but RSV, measles, adenovirus, and influenza can all cause croup as well.
W... | 42,100 | [
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People with the following characteristics are at the highest risk for croup:
Infants and children between 6 months and 6 years old Males People living in densely populated regions People traveling to and from developing countries People without an influenza vaccine
Who is at highest risk... | 42,101 | [
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Most people who are infected with enterovirus 68 only develop mild disease. Symptoms may include:
Fever Runny nose Sneezing Cough Skin rash
The disease may be more severe in younger children and require hospitalization. Children may have:
Difficulty breathing Wheezing or worsening of ast... | 42,304 | [
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Most persons with enterovirus 68 infection recover fully without any long-term health problems. In a minority of patients, particularly children, the virus may lead to a severe infection of the lungs (pneumonia) requiring hospitalization, and very rarely leading to death.
What to expect ... | 42,309 | [
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Symptoms vary and differ with age. They usually appear 4 - 6 days after coming in contact with the virus. Older children usually have only mild, cold-like symptoms, such as cough, stuffy nose, or low-grade fever. Infants under age 1 may have more severe symptoms and often have the most t... | 42,611 | [
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RSV is the most common germ that causes lung and airway infections in infants and young children. Most infants have had this infection by age 2. Outbreaks of RSV infections most often begin in the fall and run into the spring. The infection can occur in people of all ages. The virus spre... | 42,612 | [
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The following increase the risk for RSV:
Attending day care Being near tobacco smoke Having school-aged brothers or sisters Living in crowded conditions
Who is at highest risk for Human respiratory syncytial virus ?
| 42,613 | [
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Rarely, RSV infection can cause death in infants. However, this is unlikely if the child is seen by a health care provider in the early stages of the disease. More severe RSV disease may occur in the following infants:
Premature infants Infants with chronic lung disease Infants whose imm... | 42,615 | [
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The flu usually begins abruptly, with a fever between 102 and 106 °F. (An adult typically has a lower fever than a child.) The fever usually lasts for a day or two, but can last 5 days.
Other common symptoms include:
Chills Dizziness Flushed face Headache Nausea Vomiting Tiredness Runny ... | 42,746 | [
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In temperate climates, influenza A usually arrives between early winter and early spring. Influenza B can appear at any time of the year.
What causes Influenza?
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If you develop a fever and symptoms of respiratory illness, such as cough or shortness of breath, within 14 days after traveling from countries in the Arabian Peninsula or neighboring countries, you should see your healthcare provider and mention your recent travel.
When to seek urgent m... | 43,009 | [
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Pertussis can cause serious illness in infants, children and adults. The disease starts like the common cold, with runny nose or congestion, sneezing, and maybe mild cough or fever. But after 1–2 weeks, severe coughing begins. Infants and children with the disease cough violently and rap... | 43,380 | [
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Those in child care centers or other settings with many young children are most at risk for infection. Unvaccinated children, aged 3 to 35 months old, can be severely infected by rotavirus. Older adults have, to some extent, a risk of getting infected. Adults who are caring for infected ... | 43,637 | [
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The hallmark symptoms are fever greater than 100.4 degrees F (38.0 degrees C) and cough, difficulty breathing, or other respiratory symptoms. Symptoms in the order of how commonly they appeared have included:
Fever Chills and shaking Muscle aches Cough Headache
Less common symptoms inclu... | 43,704 | [
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