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Title: Particle learning of Gaussian process models for sequential design and optimization
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Abstract: We develop a simulation-based method for the online updating of Gaussian process regression and classification models. Our method exploits sequential Monte Carlo to produce a fast sequential design algorithm for these models relative to the established MCMC alternative. The latter is less ideal for sequential design since it must be restarted and iterated to convergence with the inclusion of each new design point. We illustrate some attractive ensemble aspects of our SMC approach, and show how active learning heuristics may be implemented via particles to optimize a noisy function or to explore classification boundaries online.
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Title: Parameter Estimation for Multivariate Diffusion Systems
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Abstract: Diffusion processes are widely used for modelling real-world phenomena. Except for select cases however, analytical expressions do not exist for a diffusion process' transitional probabilities. It is proposed that the cumulant truncation procedure can be applied to predict the evolution of the cumulants of the system. These predictions may be subsequently used within the saddlepoint procedure to approximate the transitional probabilities. An approximation to the likelihood of the diffusion system is then easily derived. The method is applicable for a wide-range of diffusion systems - including multivariate, irreducible diffusion systems that existing estimation schemes struggle with. Not only is the accuracy of the saddlepoint comparable with the Hermite expansion - a popular approximation to a diffusion system's transitional density - it also appears to be less susceptible to increasing lags between successive samplings of the diffusion process. Furthermore, the saddlepoint is more stable in regions of the parameter space that are far from the maximum likelihood estimates. Hence, the saddlepoint method can be naturally incorporated within a Markov Chain Monte Carlo (MCMC) routine in order to provide reliable estimates and credibility intervals of the diffusion model's parameters. The method is applied to fit the Heston model to daily observations of the S&P 500 and VIX indices from December 2009 to November 2010.
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Title: On the relevance of the Bayesian approach to Statistics
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Abstract: We argue here about the relevance and the ultimate unity of the Bayesian approach in a neutral and agnostic manner. Our main theme is that Bayesian data analysis is an effective tool for handling complex models, as proven by the increasing proportion of Bayesian studies in the applied sciences. We disregard in this essay the philosophical debates on the deeper meaning of probability and on the random nature of parameters as things of the past that do a disservice to the approach and are incomprehensible to most bystanders.
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Title: Errors-in-variables models: a generalized functions approach
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Abstract: Identification in errors-in-variables regression models was recently extended to wide models classes by S. Schennach (Econometrica, 2007) (S) via use of generalized functions. In this paper the problems of non- and semi- parametric identification in such models are re-examined. Nonparametric identification holds under weaker assumptions than in (S); the proof here does not rely on decomposition of generalized functions into ordinary and singular parts, which may not hold. A consistent nonparametric plug-in estimator for regression functions in the space of absolutely integrable functions constructed. Semiparametric identification via a finite set of moments is shown to hold for classes of functions that are explicitly characterized; unlike (S) existence of a moment generating function for the measurement error is not required.
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Title: Laplacian Support Vector Machines Trained in the Primal
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Abstract: In the last few years, due to the growing ubiquity of unlabeled data, much effort has been spent by the machine learning community to develop better understanding and improve the quality of classifiers exploiting unlabeled data. Following the manifold regularization approach, Laplacian Support Vector Machines (LapSVMs) have shown the state of the art performance in semi--supervised classification. In this paper we present two strategies to solve the primal LapSVM problem, in order to overcome some issues of the original dual formulation. Whereas training a LapSVM in the dual requires two steps, using the primal form allows us to collapse training to a single step. Moreover, the computational complexity of the training algorithm is reduced from O(n^3) to O(n^2) using preconditioned conjugate gradient, where n is the combined number of labeled and unlabeled examples. We speed up training by using an early stopping strategy based on the prediction on unlabeled data or, if available, on labeled validation examples. This allows the algorithm to quickly compute approximate solutions with roughly the same classification accuracy as the optimal ones, considerably reducing the training time. Due to its simplicity, training LapSVM in the primal can be the starting point for additional enhancements of the original LapSVM formulation, such as those for dealing with large datasets. We present an extensive experimental evaluation on real world data showing the benefits of the proposed approach.
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Title: Guaranteed Rank Minimization via Singular Value Projection
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Abstract: Minimizing the rank of a matrix subject to affine constraints is a fundamental problem with many important applications in machine learning and statistics. In this paper we propose a simple and fast algorithm SVP (Singular Value Projection) for rank minimization with affine constraints (ARMP) and show that SVP recovers the minimum rank solution for affine constraints that satisfy the "restricted isometry property" and show robustness of our method to noise. Our results improve upon a recent breakthrough by Recht, Fazel and Parillo (RFP07) and Lee and Bresler (LB09) in three significant ways: 1) our method (SVP) is significantly simpler to analyze and easier to implement, 2) we give recovery guarantees under strictly weaker isometry assumptions 3) we give geometric convergence guarantees for SVP even in presense of noise and, as demonstrated empirically, SVP is significantly faster on real-world and synthetic problems. In addition, we address the practically important problem of low-rank matrix completion (MCP), which can be seen as a special case of ARMP. We empirically demonstrate that our algorithm recovers low-rank incoherent matrices from an almost optimal number of uniformly sampled entries. We make partial progress towards proving exact recovery and provide some intuition for the strong performance of SVP applied to matrix completion by showing a more restricted isometry property. Our algorithm outperforms existing methods, such as those of , for ARMP and the matrix-completion problem by an order of magnitude and is also significantly more robust to noise.
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Title: Information tracking approach to segmentation of ultrasound imagery of prostate
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Abstract: The size and geometry of the prostate are known to be pivotal quantities used by clinicians to assess the condition of the gland during prostate cancer screening. As an alternative to palpation, an increasing number of methods for estimation of the above-mentioned quantities are based on using imagery data of prostate. The necessity to process large volumes of such data creates a need for automatic segmentation tools which would allow the estimation to be carried out with maximum accuracy and efficiency. In particular, the use of transrectal ultrasound (TRUS) imaging in prostate cancer screening seems to be becoming a standard clinical practice due to the high benefit-to-cost ratio of this imaging modality. Unfortunately, the segmentation of TRUS images is still hampered by relatively low contrast and reduced SNR of the images, thereby requiring the segmentation algorithms to incorporate prior knowledge about the geometry of the gland. In this paper, a novel approach to the problem of segmenting the TRUS images is described. The proposed approach is based on the concept of distribution tracking, which provides a unified framework for modeling and fusing image-related and morphological features of the prostate. Moreover, the same framework allows the segmentation to be regularized via using a new type of "weak" shape priors, which minimally bias the estimation procedure, while rendering the latter stable and robust.
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Title: Iterative Shrinkage Approach to Restoration of Optical Imagery
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Abstract: The problem of reconstruction of digital images from their degraded measurements is regarded as a problem of central importance in various fields of engineering and imaging sciences. In such cases, the degradation is typically caused by the resolution limitations of an imaging device in use and/or by the destructive influence of measurement noise. Specifically, when the noise obeys a Poisson probability law, standard approaches to the problem of image reconstruction are based on using fixed-point algorithms which follow the methodology first proposed by Richardson and Lucy. The practice of using these methods, however, shows that their convergence properties tend to deteriorate at relatively high noise levels. Accordingly, in the present paper, a novel method for de-noising and/or de-blurring of digital images corrupted by Poisson noise is introduced. The proposed method is derived under the assumption that the image of interest can be sparsely represented in the domain of a linear transform. Consequently, a shrinkage-based iterative procedure is proposed, which guarantees the solution to converge to the global maximizer of an associated maximum-a-posteriori criterion. It is shown in a series of both computer-simulated and real-life experiments that the proposed method outperforms a number of existing alternatives in terms of stability, precision, and computational efficiency.
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Title: Improvements of the 3D images captured with Time-of-Flight cameras
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Abstract: 3D Time-of-Flight camera's images are affected by errors due to the diffuse (indirect) light and to the flare light. The presented method improves the 3D image reducing the distance's errors to dark surface objects. This is achieved by placing one or two contrast tags in the scene at different distances from the ToF camera. The white and black parts of the tags are situated at the same distance to the camera but the distances measured by the camera are different. This difference is used to compute a correction vector. The distance to black surfaces is corrected by subtracting this vector from the captured vector image.
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Title: Model choice versus model criticism
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Abstract: The new perspectives on ABC and Bayesian model criticisms presented in Ratmann et al.(2009) are challenging standard approaches to Bayesian model choice. We discuss here some issues arising from the authors' approach, including prior influence, model assessment and criticism, and the meaning of error in ABC.
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Title: Algorithms for finding dispensable variables
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Abstract: This short note reviews briefly three algorithms for finding the set of dispensable variables of a boolean formula. The presentation is light on proofs and heavy on intuitions.
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Title: Finding Associations and Computing Similarity via Biased Pair Sampling
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Abstract: This version is ***superseded*** by a full version that can be found at http://www.itu.dk/people/pagh/papers/mining-jour.pdf, which contains stronger theoretical results and fixes a mistake in the reporting of experiments. Abstract: Sampling-based methods have previously been proposed for the problem of finding interesting associations in data, even for low-support items. While these methods do not guarantee precise results, they can be vastly more efficient than approaches that rely on exact counting. However, for many similarity measures no such methods have been known. In this paper we show how a wide variety of measures can be supported by a simple biased sampling method. The method also extends to find high-confidence association rules. We demonstrate theoretically that our method is superior to exact methods when the threshold for "interesting similarity/confidence" is above the average pairwise similarity/confidence, and the average support is not too low. Our method is particularly good when transactions contain many items. We confirm in experiments on standard association mining benchmarks that this gives a significant speedup on real data sets (sometimes much larger than the theoretical guarantees). Reductions in computation time of over an order of magnitude, and significant savings in space, are observed.
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Title: Expectation Propagation on the Maximum of Correlated Normal Variables
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Abstract: Many inference problems involving questions of optimality ask for the maximum or the minimum of a finite set of unknown quantities. This technical report derives the first two posterior moments of the maximum of two correlated Gaussian variables and the first two posterior moments of the two generating variables (corresponding to Gaussian approximations minimizing relative entropy). It is shown how this can be used to build a heuristic approximation to the maximum relationship over a finite set of Gaussian variables, allowing approximate inference by Expectation Propagation on such quantities.
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Title: Compressed Blind De-convolution
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Abstract: Suppose the signal x is realized by driving a k-sparse signal u through an arbitrary unknown stable discrete-linear time invariant system H. These types of processes arise naturally in Reflection Seismology. In this paper we are interested in several problems: (a) Blind-Deconvolution: Can we recover both the filter $H$ and the sparse signal $u$ from noisy measurements? (b) Compressive Sensing: Is x compressible in the conventional sense of compressed sensing? Namely, can x, u and H be reconstructed from a sparse set of measurements. We develop novel L1 minimization methods to solve both cases and establish sufficient conditions for exact recovery for the case when the unknown system H is auto-regressive (i.e. all pole) of a known order. In the compressed sensing/sampling setting it turns out that both H and x can be reconstructed from O(k log(n)) measurements under certain technical conditions on the support structure of u. Our main idea is to pass x through a linear time invariant system G and collect O(k log(n)) sequential measurements. The filter G is chosen suitably, namely, its associated Toeplitz matrix satisfies the RIP property. We develop a novel LP optimization algorithm and show that both the unknown filter H and the sparse input u can be reliably estimated.
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Title: Markov Chain Order Estimation and Relative Entropy
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Abstract: We use the $f-divergence$ also called relative entropy as a measure of diversity between probability densities and review its basic properties. In the sequence we define a few objects which capture relevant information from the sample of a Markov Chain to be used in the definition of a couple of estimators i.e. the Local Dependency Level and Global Dependency Level for a Markov chain sample. After exploring their properties we propose a new estimator for the Markov chain order. Finally we show a few tables containing numerical simulation results, comparing the performance of the new estimator with the well known and already established AIC and BIC estimators.
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Title: Post-Processing of Discovered Association Rules Using Ontologies
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Abstract: In Data Mining, the usefulness of association rules is strongly limited by the huge amount of delivered rules. In this paper we propose a new approach to prune and filter discovered rules. Using Domain Ontologies, we strengthen the integration of user knowledge in the post-processing task. Furthermore, an interactive and iterative framework is designed to assist the user along the analyzing task. On the one hand, we represent user domain knowledge using a Domain Ontology over database. On the other hand, a novel technique is suggested to prune and to filter discovered rules. The proposed framework was applied successfully over the client database provided by Nantes Habitat.
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Title: Statistical Decision Making for Authentication and Intrusion Detection
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Abstract: User authentication and intrusion detection differ from standard classification problems in that while we have data generated from legitimate users, impostor or intrusion data is scarce or non-existent. We review existing techniques for dealing with this problem and propose a novel alternative based on a principled statistical decision-making view point. We examine the technique on a toy problem and validate it on complex real-world data from an RFID based access control system. The results indicate that it can significantly outperform the classical world model approach. The method could be more generally useful in other decision-making scenarios where there is a lack of adversary data.
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Title: A path algorithm for the Fused Lasso Signal Approximator
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Abstract: The Lasso is a very well known penalized regression model, which adds an $L_1$ penalty with parameter $\lambda_1$ on the coefficients to the squared error loss function. The Fused Lasso extends this model by also putting an $L_1$ penalty with parameter $\lambda_2$ on the difference of neighboring coefficients, assuming there is a natural ordering. In this paper, we develop a fast path algorithm for solving the Fused Lasso Signal Approximator that computes the solutions for all values of $\lambda_1$ and $\lambda_2$. In the supplement, we also give an algorithm for the general Fused Lasso for the case with predictor matrix $\bX \in ^n \times p$ with $(\bX)=p$.
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Title: A Note On Higher Order Grammar
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Abstract: Both syntax-phonology and syntax-semantics interfaces in Higher Order Grammar (HOG) are expressed as axiomatic theories in higher-order logic (HOL), i.e. a language is defined entirely in terms of provability in the single logical system. An important implication of this elegant architecture is that the meaning of a valid expression turns out to be represented not by a single, nor even by a few "discrete" terms (in case of ambiguity), but by a "continuous" set of logically equivalent terms. The note is devoted to precise formulation and proof of this observation.
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Title: Pre-processing in AI based Prediction of QSARs
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Abstract: Machine learning, data mining and artificial intelligence (AI) based methods have been used to determine the relations between chemical structure and biological activity, called quantitative structure activity relationships (QSARs) for the compounds. Pre-processing of the dataset, which includes the mapping from a large number of molecular descriptors in the original high dimensional space to a small number of components in the lower dimensional space while retaining the features of the original data, is the first step in this process. A common practice is to use a mapping method for a dataset without prior analysis. This pre-analysis has been stressed in our work by applying it to two important classes of QSAR prediction problems: drug design (predicting anti-HIV-1 activity) and predictive toxicology (estimating hepatocarcinogenicity of chemicals). We apply one linear and two nonlinear mapping methods on each of the datasets. Based on this analysis, we conclude the nature of the inherent relationships between the elements of each dataset, and hence, the mapping method best suited for it. We also show that proper preprocessing can help us in choosing the right feature extraction tool as well as give an insight about the type of classifier pertinent for the given problem.
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Title: Regularization Techniques for Learning with Matrices
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Abstract: There is growing body of learning problems for which it is natural to organize the parameters into matrix, so as to appropriately regularize the parameters under some matrix norm (in order to impose some more sophisticated prior knowledge). This work describes and analyzes a systematic method for constructing such matrix-based, regularization methods. In particular, we focus on how the underlying statistical properties of a given problem can help us decide which regularization function is appropriate. Our methodology is based on the known duality fact: that a function is strongly convex with respect to some norm if and only if its conjugate function is strongly smooth with respect to the dual norm. This result has already been found to be a key component in deriving and analyzing several learning algorithms. We demonstrate the potential of this framework by deriving novel generalization and regret bounds for multi-task learning, multi-class learning, and kernel learning.
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Title: Variable sigma Gaussian processes: An expectation propagation perspective
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Abstract: Gaussian processes (GPs) provide a probabilistic nonparametric representation of functions in regression, classification, and other problems. Unfortunately, exact learning with GPs is intractable for large datasets. A variety of approximate GP methods have been proposed that essentially map the large dataset into a small set of basis points. The most advanced of these, the variable-sigma GP (VSGP) (Walder et al., 2008), allows each basis point to have its own length scale. However, VSGP was only derived for regression. We describe how VSGP can be applied to classification and other problems, by deriving it as an expectation propagation algorithm. In this view, sparse GP approximations correspond to a KL-projection of the true posterior onto a compact exponential family of GPs. VSGP constitutes one such family, and we show how to enlarge this family to get additional accuracy. In particular, we show that endowing each basis point with its own full covariance matrix provides a significant increase in approximation power.
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Title: On the conditions used to prove oracle results for the Lasso
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Abstract: Oracle inequalities and variable selection properties for the Lasso in linear models have been established under a variety of different assumptions on the design matrix. We show in this paper how the different conditions and concepts relate to each other. The restricted eigenvalue condition (Bickel et al., 2009) or the slightly weaker compatibility condition (van de Geer, 2007) are sufficient for oracle results. We argue that both these conditions allow for a fairly general class of design matrices. Hence, optimality of the Lasso for prediction and estimation holds for more general situations than what it appears from coherence (Bunea et al, 2007b,c) or restricted isometry (Candes and Tao, 2005) assumptions.
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Title: Estimating the null distribution for conditional inference and genome-scale screening
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Abstract: In a novel approach to the multiple testing problem, Efron (2004; 2007) formulated estimators of the distribution of test statistics or nominal p-values under a null distribution suitable for modeling the data of thousands of unaffected genes, non-associated single-nucleotide polymorphisms, or other biological features. Estimators of the null distribution can improve not only the empirical Bayes procedure for which it was originally intended, but also many other multiple comparison procedures. Such estimators serve as the groundwork for the proposed multiple comparison procedure based on a recent frequentist method of minimizing posterior expected loss, exemplified with a non-additive loss function designed for genomic screening rather than for validation. The merit of estimating the null distribution is examined from the vantage point of conditional inference in the remainder of the paper. In a simulation study of genome-scale multiple testing, conditioning the observed confidence level on the estimated null distribution as an approximate ancillary statistic markedly improved conditional inference. To enable researchers to determine whether to rely on a particular estimated null distribution for inference or decision making, an information-theoretic score is provided that quantifies the benefit of conditioning. As the sum of the degree of ancillarity and the degree of inferential relevance, the score reflects the balance conditioning would strike between the two conflicting terms. Applications to gene expression microarray data illustrate the methods introduced.
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Title: Prediction of Zoonosis Incidence in Human using Seasonal Auto Regressive Integrated Moving Average (SARIMA)
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Abstract: Zoonosis refers to the transmission of infectious diseases from animal to human. The increasing number of zoonosis incidence makes the great losses to lives, including humans and animals, and also the impact in social economic. It motivates development of a system that can predict the future number of zoonosis occurrences in human. This paper analyses and presents the use of Seasonal Autoregressive Integrated Moving Average (SARIMA) method for developing a forecasting model that able to support and provide prediction number of zoonosis human incidence. The dataset for model development was collected on a time series data of human tuberculosis occurrences in United States which comprises of fourteen years of monthly data obtained from a study published by Centers for Disease Control and Prevention (CDC). Several trial models of SARIMA were compared to obtain the most appropriate model. Then, diagnostic tests were used to determine model validity. The result showed that the SARIMA(9,0,14)(12,1,24)12 is the fittest model. While in the measure of accuracy, the selected model achieved 0.062 of Theils U value. It implied that the model was highly accurate and a close fit. It was also indicated the capability of final model to closely represent and made prediction based on the tuberculosis historical dataset.
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Title: Reduced-Rank Hidden Markov Models
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Abstract: We introduce the Reduced-Rank Hidden Markov Model (RR-HMM), a generalization of HMMs that can model smooth state evolution as in Linear Dynamical Systems (LDSs) as well as non-log-concave predictive distributions as in continuous-observation HMMs. RR-HMMs assume an m-dimensional latent state and n discrete observations, with a transition matrix of rank k <= m. This implies the dynamics evolve in a k-dimensional subspace, while the shape of the set of predictive distributions is determined by m. Latent state belief is represented with a k-dimensional state vector and inference is carried out entirely in R^k, making RR-HMMs as computationally efficient as k-state HMMs yet more expressive. To learn RR-HMMs, we relax the assumptions of a recently proposed spectral learning algorithm for HMMs (Hsu, Kakade and Zhang 2009) and apply it to learn k-dimensional observable representations of rank-k RR-HMMs. The algorithm is consistent and free of local optima, and we extend its performance guarantees to cover the RR-HMM case. We show how this algorithm can be used in conjunction with a kernel density estimator to efficiently model high-dimensional multivariate continuous data. We also relax the assumption that single observations are sufficient to disambiguate state, and extend the algorithm accordingly. Experiments on synthetic data and a toy video, as well as on a difficult robot vision modeling problem, yield accurate models that compare favorably with standard alternatives in simulation quality and prediction capability.
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Title: Low-rank Matrix Completion with Noisy Observations: a Quantitative Comparison
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Abstract: We consider a problem of significant practical importance, namely, the reconstruction of a low-rank data matrix from a small subset of its entries. This problem appears in many areas such as collaborative filtering, computer vision and wireless sensor networks. In this paper, we focus on the matrix completion problem in the case when the observed samples are corrupted by noise. We compare the performance of three state-of-the-art matrix completion algorithms (OptSpace, ADMiRA and FPCA) on a single simulation platform and present numerical results. We show that in practice these efficient algorithms can be used to reconstruct real data matrices, as well as randomly generated matrices, accurately.
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Title: BRAINSTORMING: Consensus Learning in Practice
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Abstract: We present here an introduction to Brainstorming approach, that was recently proposed as a consensus meta-learning technique, and used in several practical applications in bioinformatics and chemoinformatics. The consensus learning denotes heterogeneous theoretical classification method, where one trains an ensemble of machine learning algorithms using different types of input training data representations. In the second step all solutions are gathered and the consensus is build between them. Therefore no early solution, given even by a generally low performing algorithm, is not discarder until the late phase of prediction, when the final conclusion is drawn by comparing different machine learning models. This final phase, i.e. consensus learning, is trying to balance the generality of solution and the overall performance of trained model.
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Title: Functional learning through kernels
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Abstract: This paper reviews the functional aspects of statistical learning theory. The main point under consideration is the nature of the hypothesis set when no prior information is available but data. Within this framework we first discuss about the hypothesis set: it is a vectorial space, it is a set of pointwise defined functions, and the evaluation functional on this set is a continuous mapping. Based on these principles an original theory is developed generalizing the notion of reproduction kernel Hilbert space to non hilbertian sets. Then it is shown that the hypothesis set of any learning machine has to be a generalized reproducing set. Therefore, thanks to a general "representer theorem", the solution of the learning problem is still a linear combination of a kernel. Furthermore, a way to design these kernels is given. To illustrate this framework some examples of such reproducing sets and kernels are given.
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Title: Building upon Fast Multipole Methods to Detect and Model Organizations
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Abstract: Many models in natural and social sciences are comprised of sets of inter-acting entities whose intensity of interaction decreases with distance. This often leads to structures of interest in these models composed of dense packs of entities. Fast Multipole Methods are a family of methods developed to help with the calculation of a number of computable models such as described above. We propose a method that builds upon FMM to detect and model the dense structures of these systems.
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Title: Distance Dependent Chinese Restaurant Processes
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Abstract: We develop the distance dependent Chinese restaurant process (CRP), a flexible class of distributions over partitions that allows for non-exchangeability. This class can be used to model many kinds of dependencies between data in infinite clustering models, including dependencies across time or space. We examine the properties of the distance dependent CRP, discuss its connections to Bayesian nonparametric mixture models, and derive a Gibbs sampler for both observed and mixture settings. We study its performance with three text corpora. We show that relaxing the assumption of exchangeability with distance dependent CRPs can provide a better fit to sequential data. We also show its alternative formulation of the traditional CRP leads to a faster-mixing Gibbs sampling algorithm than the one based on the original formulation.
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Title: A multiagent urban traffic simulation. Part II: dealing with the extraordinary
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Abstract: In Probabilistic Risk Management, risk is characterized by two quantities: the magnitude (or severity) of the adverse consequences that can potentially result from the given activity or action, and by the likelihood of occurrence of the given adverse consequences. But a risk seldom exists in isolation: chain of consequences must be examined, as the outcome of one risk can increase the likelihood of other risks. Systemic theory must complement classic PRM. Indeed these chains are composed of many different elements, all of which may have a critical importance at many different levels. Furthermore, when urban catastrophes are envisioned, space and time constraints are key determinants of the workings and dynamics of these chains of catastrophes: models must include a correct spatial topology of the studied risk. Finally, literature insists on the importance small events can have on the risk on a greater scale: urban risks management models belong to self-organized criticality theory. We chose multiagent systems to incorporate this property in our model: the behavior of an agent can transform the dynamics of important groups of them.
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Title: Time-varying Coefficients Estimation in Differential Equation Models with Noisy Time-varying Covariates
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Abstract: We study the problem of estimating time-varying coefficients in ordinary differential equations. Current theory only applies to the case when the associated state variables are observed without measurement errors as presented in . The difficulty arises from the quadratic functional of observations that one needs to deal with instead of the linear functional that appears when state variables contain no measurement errors. We derive the asymptotic bias and variance for the previously proposed two-step estimators using quadratic regression functional theory.
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Title: A Local Search Modeling for Constrained Optimum Paths Problems (Extended Abstract)
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