Datasets:
license: cc-by-nc-sa-3.0
pretty_name: Mindboggle-101
tags:
- medical
- mri
- brain
- t1-weighted
- cortical-parcellation
- brain-segmentation
- neuroimaging
task_categories:
- image-segmentation
size_categories:
- n<1K
dataset_info:
features:
- name: subject_id
dtype: string
- name: cohort
dtype: string
- name: source_archive
dtype: string
- name: sex
dtype: string
- name: age
dtype: string
- name: image_shape
dtype: string
- name: num_slices
dtype: int32
- name: voxel_spacing
dtype: string
- name: num_cortical_regions
dtype: int32
- name: image
dtype: image
- name: mask
dtype: image
- name: overlay
dtype: image
splits:
- name: train
num_bytes: 9419820
num_examples: 101
download_size: 9426186
dataset_size: 9419820
configs:
- config_name: default
data_files:
- split: train
path: data/train-*
Mindboggle-101
Manually-labeled cortical parcellations for 101 healthy-adult T1-weighted brain MRI volumes, following the Desikan-Killiany-Tourville (DKT) protocol. This is the largest set of consistently, manually labeled human brains and is the reference behind the DKT cortical atlas shipped inside FreeSurfer.
Scope of this mirror — read before use. This repository is the volumetric subset of the full Mindboggle-101 distribution: image volumes + manual cortical label volumes. The FreeSurfer surface meshes/labels and the shape-feature tables that the official deposit also contains are not included (they are not voxel segmentation masks) — obtain them from the Harvard Dataverse DOIs below. The whole-brain (cortex+subcortex) volume labels for the OASIS-TRT-20 cohort, and the per-subject
+aseg(cortical+subcortical) variants, are excluded — see Licensing.
Contents
101 subjects, one T1 brain each, organized by source cohort (no train/val/test split):
| Cohort | N | Origin archive |
|---|---|---|
| NKI-RS-22 | 22 | Nathan Kline Institute – Rockland Sample |
| MMRR-21 | 21 | Multi-Modal MRI Reproducibility Resource |
| NKI-TRT-20 | 20 | NKI Test–Retest |
| OASIS-TRT-20 | 20 | OASIS cross-sectional, test–retest |
| Extra-18 | 18 | HLN-12 + MMRR-3T7T-2 + Twins-2 + Colin27-1 + Afterthought-1 |
| Total | 101 |
Per subject — <Cohort>_volumes/<Subject-ID>/:
| File | Description |
|---|---|
t1weighted.nii.gz |
Native-space T1 (≈256³, 1 mm isotropic, int16) |
t1weighted_brain.nii.gz |
Skull-stripped native T1 |
t1weighted.MNI152.nii.gz |
T1 affinely registered to MNI152 |
t1weighted_brain.MNI152.nii.gz |
Skull-stripped T1 in MNI152 |
t1weighted_brain.MNI152.affine.txt |
Native→MNI152 affine |
labels.DKT31.manual.nii.gz |
Gold-standard manual DKT31 cortical labels (native space) |
labels.DKT31.manual.MNI152.nii.gz |
Same labels in MNI152 space |
Also at the repo root: subject_sources_Mindboggle101.txt, subject_list_Mindboggle101.txt,
label_definitions.txt, label-issues_201903.txt, subject_table_Mindboggle101.pdf,
scans/ (per-cohort acquisition info), and the Apache-2.0 code_* helper files.
Ground truth & label scheme
Recommended evaluation reference: labels.DKT31.manual.nii.gz — manually-edited cortical
parcellation, 62 cortical regions (31 per hemisphere) + background. FreeSurfer/aparc-style
integer codes are stored as float32 (cast to int on load):
- Left hemisphere
1002–1035; right hemisphere2002–2035. Codes are non-contiguous (e.g. 1004/1032/1033 absent — those regions are excluded under DKT31); remap to a contiguous 0…62 range for training/scoring. - Region names per code: see
label_definitions.txt. - Cortex is a thin ribbon → ~95 % of voxels are background (label 0); expect strong class imbalance.
The reduced DKT25 scheme and the FreeSurfer-aseg whole-brain variants exist only in the
surface / +aseg products and are not in this volumetric mirror.
Cross-dataset overlap (important)
Every Mindboggle-101 subject is drawn from another public dataset (OASIS, NKI-RS, NKI-TRT,
MMRR, the MNI Colin27 template). Before combining this with any OASIS- or NKI-derived benchmark,
de-duplicate using subject_sources_Mindboggle101.txt (preserved at the repo root), which
maps each Mindboggle ID (e.g. OASIS-TRT-20-1) back to its original-archive identifier. The DKT
atlas derived from these brains also ships inside FreeSurfer (aparc.DKTatlas), and CerebrA is a
corrected MNI-registered derivative. No shared lineage with the BraTS family or the Medical
Segmentation Decathlon.
Licensing (per component)
This mirror follows the authors' own copyright notices shipped inside the data, which are more authoritative than third-party host tags:
| Component | License | Where stated |
|---|---|---|
| T1 images + manual DKT cortical labels (the 101 subjects) | CC BY-NC-SA 3.0 | subject_sources_Mindboggle101.txt (Mindboggle team, 2012) |
Labeling-protocol doc + helper code (label_definitions.txt, code_*) |
Apache-2.0 | bundled file headers |
| (excluded) OASIS-TRT-20 whole-brain cortex+subcortex labels | CC BY-NC-ND 3.0 | Neuromorphometrics BrainCOLOR-derived |
- The repo
license:tag iscc-by-nc-sa-3.0, reflecting the image+label data (the primary content): non-commercial, attribution required, derivatives shared alike. - Harvard Dataverse tags the primary image/label files CC0; we intentionally adopt the more restrictive CC BY-NC-SA 3.0 from the authors' bundled notice as the safer reading of the conflicting signals (NITRC also lists CC BY-NC-SA 3.0).
- The CC BY-NC-ND subcortical whole-brain labels were dropped so this repository can be cleanly redistributed and previewed; obtain them from the Dataverse DOI below if required.
Provenance & source
Author-maintained: https://mindboggle.info/data.html · OSF nhtur ·
Harvard Dataverse — individual brains doi:10.7910/DVN/HMQKCK
(this mirror's source), atlases doi:10.7910/DVN/XCCE9Q, templates doi:10.7910/DVN/WDIYB5.
Subject count verified against the paper: 101/101.
data/ preview
The data/ directory holds a Parquet preview (middle-axial-slice PNG + cortical-label overlay per
volume) for the Hugging Face Dataset Viewer. Previews are rendered only from the CC BY-NC-SA
cortical labels. The authoritative data are the raw .nii.gz files in the *_volumes/ folders.
Citation
Klein A, Tourville J. 101 labeled brain images and a consistent human cortical labeling protocol. Frontiers in Neuroscience 6:171, 2012. doi:10.3389/fnins.2012.00171
Please also acknowledge the source archives (OASIS, NKI / Rockland, MMRR) per their terms when using the corresponding cohorts.