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{"patient_id":"ANODE_SYNTH_2025_1972","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":7.2,"microsatellite_status":"MSS","pd_l1_tps_percent":5},"basel... |
{"patient_id":"ANODE_SYNTH_2025_1973","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":13.3,"microsatellite_status":"MSS","pd_l1_tps_percent":28},"bas... |
{"patient_id":"ANODE_SYNTH_2025_1974","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":3.2,"microsatellite_status":"MSS","pd_l1_tps_percent":24},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1975","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":7.6,"microsatellite_status":"MSS","pd_l1_tps_percent":25},"base... |
{"patient_id":"ANODE_SYNTH_2025_1976","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.0,"microsatellite_status":"MSS","pd_l1_tps_percent":7},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1977","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.5,"microsatellite_status":"MSS","pd_l1_tps_percent":30},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1978","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":9.4,"microsatellite_status":"MSS","pd_l1_tps_percent":0},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1979","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.2,"microsatellite_status":"MSS","pd_l1_tps_percent":3},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1980","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":6.7,"microsatellite_status":"MSS","pd_l1_tps_percent":25},"base... |
{"patient_id":"ANODE_SYNTH_2025_1981","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":14.9,"microsatellite_status":"MSS","pd_l1_tps_percent":21},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1982","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":9.8,"microsatellite_status":"MSS","pd_l1_tps_percent":33},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1983","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":17.9,"microsatellite_status":"MSS","pd_l1_tps_percent":15},"bas... |
{"patient_id":"ANODE_SYNTH_2025_1984","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.9,"microsatellite_status":"MSS","pd_l1_tps_percent":30},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1985","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":3.0,"microsatellite_status":"MSS","pd_l1_tps_percent":11},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1986","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":2.4,"microsatellite_status":"MSS","pd_l1_tps_percent":27},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1987","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":5.5,"microsatellite_status":"MSS","pd_l1_tps_percent":21},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1988","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":10.2,"microsatellite_status":"MSS","pd_l1_tps_percent":10},"bas... |
{"patient_id":"ANODE_SYNTH_2025_1989","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.9,"microsatellite_status":"MSS","pd_l1_tps_percent":13},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1990","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":7.7,"microsatellite_status":"MSS","pd_l1_tps_percent":13},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_1991","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.1,"microsatellite_status":"MSS","pd_l1_tps_percent":6},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_1992","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":6.1,"microsatellite_status":"MSS","pd_l1_tps_percent":16},"base... |
{"patient_id":"ANODE_SYNTH_2025_1993","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":2.9,"microsatellite_status":"MSS","pd_l1_tps_percent":1},"baseline_clinical"... |
{"patient_id":"ANODE_SYNTH_2025_1994","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":5.7,"microsatellite_status":"MSS","pd_l1_tps_percent":24},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1995","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":7.2,"microsatellite_status":"MSS","pd_l1_tps_percent":27},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1996","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":11.8,"microsatellite_status":"MSS","pd_l1_tps_percent":26},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_1997","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.6,"microsatellite_status":"MSS","pd_l1_tps_percent":30},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_1998","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":3.0,"microsatellite_status":"MSS","pd_l1_tps_percent":17},... |
{"patient_id":"ANODE_SYNTH_2025_1999","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":10.9,"microsatellite_status":"MSS","pd_l1_tps_percent":22},"bas... |
{"patient_id":"ANODE_SYNTH_2025_2000","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":13.2,"microsatellite_status":"MSS","pd_l1_tps_percent":31},"baseline_clinica... |
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