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{"patient_id":"ANODE_SYNTH_2025_2373","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"NTRK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":15.2,"microsatellite_status":"MSS","pd_l1_tps_percent":24},"baseline_clin... |
{"patient_id":"ANODE_SYNTH_2025_2374","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":12.1,"microsatellite_status":"MSS","pd_l1_tps_percent":31},"bas... |
{"patient_id":"ANODE_SYNTH_2025_2375","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":10.4,"microsatellite_status":"MSS","pd_l1_tps_percent":9},"bas... |
{"patient_id":"ANODE_SYNTH_2025_2376","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":5.7,"microsatellite_status":"MSS","pd_l1_tps_percent":0},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_2377","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":14.1,"microsatellite_status":"MSS","pd_l1_tps_percent":17}... |
{"patient_id":"ANODE_SYNTH_2025_2378","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.1,"microsatellite_status":"MSS","pd_l1_tps_percent":33},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_2379","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":10.7,"microsatellite_status":"MSS","pd_l1_tps_percent":18},"baseline_clin... |
{"patient_id":"ANODE_SYNTH_2025_2380","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":7.6,"microsatellite_status":"MSS","pd_l1_tps_percent":7},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_2381","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":14.9,"microsatellite_status":"MSS","pd_l1_tps_percent":7},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_2382","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.8,"microsatellite_status":"MSS","pd_l1_tps_percent":8},"b... |
{"patient_id":"ANODE_SYNTH_2025_2383","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":5.1,"microsatellite_status":"MSS","pd_l1_tps_percent":3},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_2384","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":5.8,"microsatellite_status":"MSS","pd_l1_tps_percent":16},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_2385","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":3.8,"microsatellite_status":"MSS","pd_l1_tps_percent":7},"baseline_clinical"... |
{"patient_id":"ANODE_SYNTH_2025_2386","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":6.2,"microsatellite_status":"MSS","pd_l1_tps_percent":11},... |
{"patient_id":"ANODE_SYNTH_2025_2387","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":17.1,"microsatellite_status":"MSS","pd_l1_tps_percent":9},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_2388","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":10.8,"microsatellite_status":"MSS","pd_l1_tps_percent":34},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_2389","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":6.4,"microsatellite_status":"MSS","pd_l1_tps_percent":21},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_2390","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":9.1,"microsatellite_status":"MSS","pd_l1_tps_percent":12},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_2391","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":12.7,"microsatellite_status":"MSS","pd_l1_tps_percent":32},"baseline_clini... |
{"patient_id":"ANODE_SYNTH_2025_2392","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.3,"microsatellite_status":"MSS","pd_l1_tps_percent":18},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_2393","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IV","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.8,"microsatellite_status":"MSS","pd_l1_tps_percent":25},"baseline_clinical... |
{"patient_id":"ANODE_SYNTH_2025_2394","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.3,"microsatellite_status":"MSS","pd_l1_tps_percent":10},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_2395","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR L858R","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":12.8,"microsatellite_status":"MSS","pd_l1_tps_percent":22},"baseline_clin... |
{"patient_id":"ANODE_SYNTH_2025_2396","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"ALK fusion","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":4.4,"microsatellite_status":"MSS","pd_l1_tps_percent":18},"baseline_clinic... |
{"patient_id":"ANODE_SYNTH_2025_2397","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"EGFR exon 19 deletion","t790m_resistance":false,"tumor_mutational_burden_mut_Mb":15.8,"microsatellite_status":"MSS","pd_l1_tps_percent":10},"ba... |
{"patient_id":"ANODE_SYNTH_2025_2398","cancer_type":"Non-small cell lung cancer","histology":"Squamous cell carcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"None (PD-L1 high)","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":17.7,"microsatellite_status":"MSS","pd_l1_tps_percent":13}... |
{"patient_id":"ANODE_SYNTH_2025_2399","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":6.8,"microsatellite_status":"MSS","pd_l1_tps_percent":27},"baseline_clinica... |
{"patient_id":"ANODE_SYNTH_2025_2400","cancer_type":"Non-small cell lung cancer","histology":"Adenocarcinoma","stage_at_diagnosis":"IVB","molecular_profile":{"driver_mutation":"KRAS G12C","t790m_resistance":null,"tumor_mutational_burden_mut_Mb":11.5,"microsatellite_status":"MSS","pd_l1_tps_percent":27},"baseline_clinic... |
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