uuid stringlengths 36 36 | full_name stringlengths 32 47 | design_model stringclasses 2
values | campaign stringclasses 3
values | target stringclasses 16
values | rank int64 1 30 | binder_length int64 50 120 | sequence stringlengths 50 120 | generator stringclasses 10
values | sequence_design_method stringclasses 4
values | n_optimization_rounds int64 0 26 | design_model_status stringclasses 6
values | adaptyv_expression stringclasses 4
values | adaptyv_binding stringclasses 5
values | adaptyv_kd_nM float64 0.03 10k ⌀ | adaptyv_kon_per_Ms float64 1k 4.46M ⌀ | adaptyv_koff_per_s float64 0 0.87 ⌀ | adaptyv_kd_is_apparent bool 2
classes | adaptyv_n_replicates float64 2 4 ⌀ | twist_expression_mg_per_mL float64 -0.02 3.18 ⌀ | twist_sec_pct_main_peak float64 15 100 ⌀ | twist_binding stringclasses 5
values | twist_kd_nM float64 0 9k ⌀ | twist_kon_per_Ms float64 300 11.3M ⌀ | twist_koff_per_s float64 0 1 ⌀ | twist_mouse_binding stringclasses 3
values | twist_mouse_kd_nM float64 0.01 9k ⌀ | twist_cyno_binding stringclasses 3
values | twist_cyno_kd_nM float64 0 9k ⌀ | twist_clec12a_binding stringclasses 3
values | twist_clec12a_kd_nM float64 10 8.2k ⌀ | twist_gdf11_binding stringclasses 2
values | twist_gdf11_kd_nM float64 | twist_cas9_apo_binding stringclasses 3
values | twist_cas9_apo_kd_nM float64 15.3 1.4k ⌀ | binder_final bool 2
classes | kd_nM_final float64 0.03 6.19k ⌀ | vendor_agreement stringclasses 7
values | mouse_binding_final stringclasses 3
values | mouse_kd_nM_final float64 0.01 9k ⌀ | cyno_binding_final stringclasses 3
values | cyno_kd_nM_final float64 0 9k ⌀ | structures_dir stringlengths 54 78 | ipsae_min_ef2fast float32 0 0.93 | sc_dockq_ef2fast float64 0 0.99 ⌀ | ipsae_min_ef2full float32 0 0.95 | sc_dockq_ef2full float64 0 0.99 ⌀ | ipsae_min_ptxv2 float32 0 0.96 | sc_dockq_ptxv2 float64 0 1 ⌀ | ipsae_min_odde float32 0 0.95 | sc_dockq_odde float64 0 0.99 ⌀ | ipsae_min_afm3 float32 0 0.86 ⌀ | sc_dockq_afm3 float64 0 0.99 ⌀ | ipsae_min_boltz2 float32 0 0.96 | sc_dockq_boltz2 float64 0 0.97 ⌀ | ipsae_min_chai1 float32 0 0.94 | sc_dockq_chai1 float64 0 0.98 ⌀ | ipsae_min_of3 float32 0 0.89 | sc_dockq_of3 float64 0 0.98 ⌀ | ipsae_min_rf3 float32 0 0.82 | sc_dockq_rf3 float64 0 0.98 ⌀ | ipsae_min_af3of3 float32 0 0.9 | sc_dockq_af3of3 float64 0 0.99 ⌀ | epitope_residues stringlengths 7 817 ⌀ | epitope_n_residues int64 0 101 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
816028de-2070-58fc-855d-889401037a4e | mythos_preview_multi_target_bbf14_rank01 | Mythos Preview | multi_target | BBF-14 | 1 | 80 | SKEERAEELGEAVRTILREAGVPEEKAEEAGREVAEAIKAGDAKKAGEIVREAAAPVFGENVAEAIGKAVEAVARKILEG | RFdiffusion3 | SolubleMPNN | 9 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.12 | 74.3083 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank01/insilico/ | 0.853314 | 0.88674 | 0.848267 | 0.93716 | 0.868875 | 0.81394 | 0.853856 | 0.89631 | 0.76709 | 0.84778 | 0.903951 | 0.83299 | 0.839437 | 0.81117 | 0.748306 | 0.79518 | 0.742515 | 0.91112 | 0.781328 | 0.90321 | B:THR18;B:TYR19;B:GLU20;B:ASP21;B:GLY22;B:LYS24;B:VAL66;B:ARG68;B:THR82;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:LEU92;B:THR94;B:LYS102;B:TYR103;B:THR104;B:THR106 | 19 |
1d5855c0-9c16-5c16-b81c-76eec408e06a | mythos_preview_multi_target_bbf14_rank02 | Mythos Preview | multi_target | BBF-14 | 2 | 80 | AAAEAIEKLGLGAEYLNLGEALFRQGKYKEAAEYYEKAVEYAEEAVRAAREAGDEVLAAAAEKLLAKARALLEQARAAAE | RFdiffusion3 | SolubleMPNN | 10 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.43 | 94.9647 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank02/insilico/ | 0.858874 | 0.88968 | 0.85031 | 0.87939 | 0.863485 | 0.89648 | 0.847691 | 0.89924 | 0.719581 | 0.86802 | 0.869428 | 0.86021 | 0.812358 | 0.86502 | 0.634031 | 0.81814 | 0.658283 | 0.87184 | 0.665836 | 0.82045 | B:THR16;B:THR18;B:TYR19;B:GLU20;B:ASP21;B:GLY22;B:LYS24;B:ASN64;B:VAL66;B:THR84;B:LEU86;B:LEU92;B:THR94;B:LYS102;B:THR104;B:THR106 | 16 |
8e55f8bf-e0d3-549d-a335-af4b1ee836fc | mythos_preview_multi_target_bbf14_rank03 | Mythos Preview | multi_target | BBF-14 | 3 | 80 | SKEERAEELGEKVRTMLREAGVPEEKAEEAGREVAEAIKAGDAKKAGEIVREAAAPVVGEAVAEAIGKAVEAAARLILEG | RFdiffusion3 | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.8 | 99.327 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank03/insilico/ | 0.850855 | 0.76381 | 0.821231 | 0.94781 | 0.866354 | 0.81525 | 0.837073 | 0.81861 | 0.698499 | 0.81844 | 0.821811 | 0.83705 | 0.234652 | 0.80272 | 0.76226 | 0.93332 | 0.575416 | 0.87057 | 0.773241 | 0.83898 | B:THR18;B:TYR19;B:GLU20;B:ASP21;B:GLY22;B:ARG68;B:THR82;B:THR84;B:LEU86;B:ASP87;B:LEU92;B:THR94;B:LYS102;B:TYR103;B:THR104;B:THR106 | 16 |
990a6d64-7947-5775-ac23-3724d3c6f619 | mythos_preview_multi_target_bbf14_rank04 | Mythos Preview | multi_target | BBF-14 | 4 | 90 | LSAEQQKILEKLKEVVEAIKAKDYEKALELLDELIKDIENSKELSEGLKAEILNMVEGVKHLIKYDPENAAALAEKVLAAIEALLAAEAA | PXDesign | SolubleMPNN | 8 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.46 | 96.7102 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank04/insilico/ | 0.871654 | 0.7711 | 0.77548 | 0.8762 | 0.862312 | 0.84557 | 0.866565 | 0.77634 | 0.705464 | 0.79469 | 0.835361 | 0.84723 | 0.815601 | 0.71881 | 0.760549 | 0.74501 | 0.672952 | 0.80924 | 0.803136 | 0.76084 | B:MET1;B:THR18;B:TYR19;B:GLU20;B:GLY22;B:LYS24;B:ASN64;B:VAL66;B:ARG68;B:THR82;B:THR84;B:GLN85;B:LEU86;B:LEU92;B:THR94;B:THR104 | 16 |
4b0b89de-de8c-5458-bef3-037fab717959 | mythos_preview_multi_target_bbf14_rank05 | Mythos Preview | multi_target | BBF-14 | 5 | 80 | AVAEAVEKLGLGAEYLNQGEALFQQGKYKEAAEYYEKAVEYAEEAVRAAREAGDEDVAAAAEKLLAKARALLEQARAAAE | RFdiffusion3 | SolubleMPNN | 5 | ordered_sequence_backbone | null | not_tested | null | null | null | null | null | 1.8 | 98.2358 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | twist_only_tested | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank05/insilico/ | 0.854898 | 0.90565 | 0.75832 | 0.83535 | 0.881216 | 0.88642 | 0.820202 | 0.88276 | 0.723538 | 0.84709 | 0.859634 | 0.89474 | 0.785174 | 0.83436 | 0.659596 | 0.80635 | 0.636887 | 0.94399 | 0.682261 | 0.96942 | B:THR16;B:THR18;B:TYR19;B:GLU20;B:GLY22;B:LYS24;B:ASN64;B:VAL66;B:THR84;B:LEU86;B:LEU92;B:THR94;B:THR104;B:THR106 | 14 |
28b4db44-e64a-5b58-a2ef-9825cb336aba | mythos_preview_multi_target_bbf14_rank06 | Mythos Preview | multi_target | BBF-14 | 6 | 90 | GAASAEEVEAALARLDELIARMERLREEHADNPEAAALLERAIATLRAERAELRETGATLSAEQLAERLAIAEALAEVVEAHARALVKAA | PXDesign | SolubleMPNN | 6 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.43 | 96.6409 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank06/insilico/ | 0.821549 | 0.7993 | 0.811565 | 0.81337 | 0.857875 | 0.69781 | 0.245598 | 0.08582 | 0 | 0.13397 | 0.190561 | 0.31523 | 0.307992 | 0.32886 | 0.240263 | 0.53131 | 0.012414 | 0.0482 | 0.780317 | 0.91155 | B:MET1;B:THR18;B:GLY22;B:ASN64;B:GLY65;B:VAL66;B:THR82;B:THR84;B:LEU86;B:LEU92;B:THR94;B:THR104 | 12 |
697ffa3f-f78a-572c-8869-11aa37cd0109 | mythos_preview_multi_target_bbf14_rank07 | Mythos Preview | multi_target | BBF-14 | 7 | 80 | MLSPADLAAVLRFVETAIEVLREVDPERAAELEERLREVKANPDDEKLLEETVIAAVEALEEHGLLAEVEDRVLAAEAAR | PXDesign | SolubleMPNN | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 0.87 | 98.4979 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank07/insilico/ | 0.80035 | 0.94918 | 0.839362 | 0.92219 | 0.834454 | 0.76639 | 0.795359 | 0.77879 | 0.701662 | 0.7427 | 0.477216 | 0.04686 | 0.451461 | 0.68009 | 0.613537 | 0.82268 | 0.614273 | 0.84257 | 0.623741 | 0.84512 | B:MET1;B:GLY2;B:THR16;B:LYS24;B:ASN64;B:GLY65;B:VAL66;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:THR90;B:LEU92;B:THR94;B:THR104;B:THR106;B:THR108 | 17 |
64591a90-512f-5a7b-8ff5-e288361882bc | mythos_preview_multi_target_bbf14_rank08 | Mythos Preview | multi_target | BBF-14 | 8 | 105 | ARAEAVEEARRRAEELGGVLVEAADLEAAREAVRRAAAEGGELTVVSVAGTAEEVEELVLALFAAAEELGLAAEIVVEPESALALRAAGPGGYAVVVLTLRVAPA | Genie3 | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.95 | 98.7131 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank08/insilico/ | 0.832491 | 0.87445 | 0.858436 | 0.93426 | 0.669674 | 0.54402 | 0.602172 | 0.45458 | 0.531816 | 0.55889 | 0.630439 | 0.55794 | 0.696547 | 0.61226 | 0.013107 | 0.64203 | 0.532459 | 0.74636 | 0.702985 | 0.73737 | B:PRO4;B:ALA7;B:LEU8;B:LEU9;B:GLY10;B:GLY11;B:PRO12;B:TYR31;B:THR32;B:ARG33;B:VAL34;B:SER35;B:PRO36;B:ARG109 | 14 |
6419c7ef-b1d6-5b22-bba6-0ff490ad2573 | mythos_preview_multi_target_bbf14_rank09 | Mythos Preview | multi_target | BBF-14 | 9 | 80 | MLSPADLAAVLEFVETAIEVLEKVDPERAKKLREKLEEVKKNPDDEKLLEELVIEAVDALEEHGLLAEVEDRVLAAQAAR | PXDesign | SolubleMPNN | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.45 | 96.5363 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank09/insilico/ | 0.790958 | 0.95616 | 0.815752 | 0.9267 | 0.822569 | 0.7399 | 0.81534 | 0.88693 | 0.68848 | 0.85736 | 0.32107 | 0.02995 | 0.24095 | 0.72486 | 0.679543 | 0.89347 | 0 | 0.02268 | 0.704393 | 0.79166 | B:MET1;B:GLY2;B:THR16;B:LYS24;B:ASN64;B:GLY65;B:VAL66;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:THR90;B:LEU92;B:THR94;B:THR104;B:THR106;B:THR108 | 17 |
6eda6654-e797-5bd2-9314-448bf9505b03 | mythos_preview_multi_target_bbf14_rank10 | Mythos Preview | multi_target | BBF-14 | 10 | 117 | AKTITQSGGGTVAEGGSVTLTNTASGLDFSKHAVAWSRQAPGQPLQTLAVISADGKIVSYAPSAEGRFTISRDIAAKKSYLNMTNLQKEDTATYYSQAVPIVGGEVLRGEGTQLTVV | BoltzGen | SolubleMPNN | 6 | ordered_sequence_backbone | null | not_tested | null | null | null | null | null | 1.6 | 77.7686 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | twist_only_tested | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank10/insilico/ | 0.806307 | 0.81278 | 0.737228 | 0.78657 | 0.644677 | 0.80198 | 0.651236 | 0.62876 | 0 | 0.06083 | 0.751745 | 0.60015 | 0.699843 | 0.68601 | 0 | 0.03796 | 0.563398 | 0.60299 | 0 | 0.03994 | B:THR16;B:ALA17;B:THR18;B:TYR19;B:GLU20;B:VAL66;B:ARG68;B:THR82;B:THR84;B:LEU86;B:ASP87;B:THR90;B:LEU92;B:THR94;B:THR104;B:THR106 | 16 |
2dda072c-2abf-5b6a-9312-712a4674794d | mythos_preview_multi_target_bbf14_rank11 | Mythos Preview | multi_target | BBF-14 | 11 | 72 | MLEFYARVGGALVYAGTLAGRPAVLVLPESEAAAPAVAARLAAAGIAFERLPGSDALLVRDASADAVAAALA | Proteina-Complexa | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 2.26 | 94.8543 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank11/insilico/ | 0.738574 | 0.97029 | 0.798345 | 0.96412 | 0.860443 | 0.96988 | 0.818947 | 0.90817 | 0.569842 | 0.8786 | 0.076902 | 0.69981 | 0.353549 | 0.83799 | 0.042796 | 0.90798 | 0.194363 | 0.83705 | 0.684896 | 0.85597 | B:THR16;B:THR18;B:TYR19;B:GLU20;B:VAL66;B:ARG68;B:THR82;B:THR84;B:LEU86;B:ASP87;B:THR90;B:THR94;B:GLY100;B:LYS102;B:THR104;B:THR106 | 16 |
947b89da-500b-5d13-9283-201da5f4e762 | mythos_preview_multi_target_bbf14_rank12 | Mythos Preview | multi_target | BBF-14 | 12 | 70 | MSEEERERLRRRLAELEAELARLKAEVAAAFAAWHADPSLITAENMAALNAQIEEVARLEAEIERLRAEL | FreeBindCraft (BindCraft) | SolubleMPNN | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.25 | 97.9546 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank12/insilico/ | 0.733115 | 0.91349 | 0.742826 | 0.86126 | 0.778039 | 0.8914 | 0.11189 | 0.01587 | 0.568863 | 0.83583 | 0.401849 | 0.82336 | 0.326852 | 0.83611 | 0.187768 | 0.83164 | 0 | 0.0233 | 0.661639 | 0.89844 | B:MET1;B:THR18;B:TYR19;B:GLU20;B:ASP21;B:GLY22;B:LYS24;B:ASN64;B:GLY65;B:VAL66;B:THR82;B:THR84;B:LEU86;B:LEU92;B:LYS102;B:THR104;B:THR106 | 17 |
67429d59-4488-58fe-ad05-a3b91f843f51 | mythos_preview_multi_target_bbf14_rank13 | Mythos Preview | multi_target | BBF-14 | 13 | 72 | MLVFYTRVGGALIYEGTLAGRPAVLVLPESPEAAPAVAARLAAAGLAFEQLPGSDALLVRGASAAAVAAALA | Proteina-Complexa | SolubleMPNN | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.89 | 92.1059 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank13/insilico/ | 0.724974 | 0.97693 | 0.796176 | 0.96718 | 0.847 | 0.96805 | 0.812123 | 0.918 | 0.572258 | 0.88867 | 0.12284 | 0.19795 | 0.076458 | 0.01669 | 0.648761 | 0.81129 | 0.397578 | 0.90798 | 0 | 0.0194 | B:THR16;B:THR18;B:TYR19;B:GLU20;B:VAL66;B:ARG68;B:THR82;B:THR84;B:LEU86;B:ASP87;B:THR90;B:THR94;B:GLY100;B:LYS102;B:THR106 | 15 |
c21e9c4b-1106-5331-87a0-b4160b4fed3c | mythos_preview_multi_target_bbf14_rank14 | Mythos Preview | multi_target | BBF-14 | 14 | 66 | RRDYQPAVDALQKAGVLDPGNKVLGYEVVGDQAHVTVQKPDGSTETVVVPATPEALAILDALIAQN | Proteina-Complexa | SolubleMPNN | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 1.58 | 98.8785 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank14/insilico/ | 0.787075 | 0.86568 | 0.74695 | 0.88312 | 0.860396 | 0.74401 | 0.647894 | 0.77368 | 0.449996 | 0.76192 | 0.423711 | 0.79446 | 0.049953 | 0.01546 | 0 | 0.01561 | 0 | 0.06484 | 0 | 0.01666 | B:MET1;B:LYS24;B:ASN64;B:VAL66;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:THR90;B:LEU92;B:THR94;B:GLY95;B:THR96;B:LYS102;B:THR104;B:THR106 | 16 |
fa0fe3db-96a1-5fc1-9775-95af10d5bdf1 | mythos_preview_multi_target_bbf14_rank15 | Mythos Preview | multi_target | BBF-14 | 15 | 89 | SGSGLAPAVAAEVRAVVEAAVARLLARDQSAEALAEALAGILARLRASGLEDVALELAARLLGLSRAEVARLSDEALLERLRRRIEAER | Genie3 | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.32 | 97.9537 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank15/insilico/ | 0.80291 | 0.80333 | 0.766887 | 0.80345 | 0.822485 | 0.67776 | 0.806485 | 0.80506 | 0.532358 | 0.73656 | 0.781578 | 0.78668 | 0.734929 | 0.77057 | 0.655095 | 0.70721 | 0.589809 | 0.6868 | 0.725946 | 0.75704 | B:MET1;B:THR18;B:TYR19;B:GLU20;B:GLY22;B:VAL66;B:THR82;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:THR90;B:LEU92;B:THR94;B:LYS102;B:TYR103;B:THR104;B:THR106 | 18 |
fdf8df98-04a9-5f36-ba70-e80e565f62e0 | mythos_preview_multi_target_bbf14_rank16 | Mythos Preview | multi_target | BBF-14 | 16 | 66 | ARDYQPAVDTLFKAGVLDPGNKVLGYEVVGDQAKVTVQKPDGSEETITVPASPEALAILDALIAQN | Proteina-Complexa | SolubleMPNN | 5 | ordered_sequence_backbone | null | not_tested | null | null | null | null | null | 2.22 | 98.5086 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | twist_only_tested | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank16/insilico/ | 0.819241 | 0.73022 | 0.718605 | 0.90282 | 0.837467 | 0.81657 | 0.761171 | 0.82499 | 0.481016 | 0.75913 | 0.863928 | 0.82102 | 0 | 0.01626 | 0.711875 | 0.95771 | 0.56707 | 0.94782 | 0.728651 | 0.81335 | B:MET1;B:LYS24;B:VAL66;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:THR90;B:LEU92;B:THR94;B:GLY95;B:THR96;B:LYS102;B:THR104;B:THR106 | 15 |
97af186f-c953-518c-867f-fab234dacac1 | mythos_preview_multi_target_bbf14_rank17 | Mythos Preview | multi_target | BBF-14 | 17 | 90 | LSEEQQEILELLRRVVEAIEAKRFEEALELLEELKEKIKNSKELSEGLKEEILNLVEGVEHHIKHDPEGAAELARKVLARIEALLKEEEA | PXDesign | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.7 | 98.0558 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank17/insilico/ | 0.805336 | 0.77357 | 0.743701 | 0.91723 | 0.79596 | 0.77171 | 0.767141 | 0.80647 | 0.647259 | 0.78183 | 0.749769 | 0.7889 | 0.753208 | 0.69558 | 0.711167 | 0.72255 | 0.564793 | 0.69524 | 0.767619 | 0.75623 | B:THR18;B:TYR19;B:GLU20;B:GLY22;B:LYS24;B:ASN64;B:VAL66;B:THR82;B:THR84;B:GLN85;B:LEU86;B:LEU92;B:THR94;B:THR104 | 14 |
31549eb9-af29-5153-942b-bd1da0a16525 | mythos_preview_multi_target_bbf14_rank18 | Mythos Preview | multi_target | BBF-14 | 18 | 70 | MSPAALAELERRIAALEAELAALKAEVAARFAAWHADPSLITAENLAALEAQIARVAALEIEIDELRARL | FreeBindCraft (BindCraft) | SolubleMPNN | 3 | ordered_sequence_backbone | none | not_expressed | null | null | null | null | 2 | 0.6 | 97.7033 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank18/insilico/ | 0.710305 | 0.85088 | 0.654675 | 0.93836 | 0.77055 | 0.81181 | 0.188678 | 0.0086 | 0 | 0.07753 | 0.223664 | 0.7995 | 0.623891 | 0.87683 | 0 | 0.74077 | 0 | 0.02149 | 0 | 0.01127 | B:MET1;B:GLY2;B:THR3;B:THR18;B:TYR19;B:GLU20;B:ASP21;B:GLY22;B:LYS24;B:ASN64;B:GLY65;B:VAL66;B:THR82;B:THR84;B:LEU86;B:LEU92;B:LYS102;B:THR104;B:THR106 | 19 |
37d218b1-9275-580b-a854-b170dac1068b | mythos_preview_multi_target_bbf14_rank19 | Mythos Preview | multi_target | BBF-14 | 19 | 90 | GAASQEELDAALAELRRLIAEARELLARHAANPEAAALLERAIARLEGELAELEKTGAKLTAEELRTLLAQARALLDSVAAHAEHLVKAA | PXDesign | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.65 | 97.364 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank19/insilico/ | 0.768614 | 0.6206 | 0.701595 | 0.82366 | 0.810254 | 0.77608 | 0.795143 | 0.80259 | 0.538131 | 0.74664 | 0.808646 | 0.77946 | 0.51807 | 0.56782 | 0.696673 | 0.84043 | 0.5631 | 0.68365 | 0.762735 | 0.70791 | B:THR18;B:TYR19;B:GLU20;B:GLY22;B:LYS24;B:ASN64;B:VAL66;B:THR82;B:THR84;B:LEU86;B:LEU92;B:THR94;B:THR104 | 13 |
5f010e9d-3469-549c-a7c5-ea00012cb34f | mythos_preview_multi_target_bbf14_rank20 | Mythos Preview | multi_target | BBF-14 | 20 | 117 | AVTITQSGGGTVPAGGSVTLTSTWSGLDFSAHDVAWLRQAPGQPRQTLAVISADGKIVSYAPEAEGRFTISRDNAAKTSKLDMRDLRPEDTATYFSAAVPVAGGEVLYGEGTPLTVV | BoltzGen | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 3.18 | 98.5895 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank20/insilico/ | 0.814668 | 0.65265 | 0.709871 | 0.7502 | 0.666121 | 0.46496 | 0.701103 | 0.66988 | 0 | 0.05386 | 0.729823 | 0.69002 | 0.012847 | 0.03271 | 0 | 0.01466 | 0.539802 | 0.6958 | 0 | 0.01769 | B:MET1;B:THR18;B:LYS24;B:VAL66;B:ARG68;B:THR82;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:THR90;B:LEU92;B:THR94;B:THR104;B:THR106 | 15 |
26d22720-d0d0-5b01-a606-afd711d43c54 | mythos_preview_multi_target_bbf14_rank21 | Mythos Preview | multi_target | BBF-14 | 21 | 90 | SLAELRALFEEFVRRLEELVGEVPEEVRELIERTLAELEALLAAGASVAELKEVARRLLVELLRRYADDAEARALAVEFYNRVVAVLESM | PXDesign | SolubleMPNN | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0 | null | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank21/insilico/ | 0.693121 | 0.73995 | 0.667373 | 0.92584 | 0.725866 | 0.74269 | 0.042675 | 0.05428 | 0.012535 | 0.5362 | 0.217551 | 0.89412 | 0.471246 | 0.72174 | 0.671219 | 0.83288 | 0.540275 | 0.7128 | 0.591621 | 0.72599 | B:MET1;B:ASN64;B:VAL66;B:ARG68;B:THR82;B:LEU92;B:THR94;B:THR104 | 8 |
381fdda5-19f3-5dc9-9491-c2111f2479a5 | mythos_preview_multi_target_bbf14_rank22 | Mythos Preview | multi_target | BBF-14 | 22 | 89 | SSAGLSPALAADVRATVRAAVARLLAEDLSAEELARRLAALARRLEASGLEGLALELLAELLGLSVAAVRALSDEELLARLEERLAAAR | Genie3 | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 0.67 | 96.3422 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank22/insilico/ | 0.717354 | 0.81178 | 0.445069 | 0.91717 | 0.816459 | 0.84525 | 0.777209 | 0.7419 | 0 | 0.30616 | 0.530912 | 0.70718 | 0.762635 | 0.70852 | 0.582475 | 0.69719 | 0 | 0.0126 | 0.471395 | 0.79197 | B:THR18;B:TYR19;B:GLU20;B:ASP21;B:GLY22;B:VAL66;B:THR82;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:LEU92;B:THR94;B:LYS102;B:THR104;B:THR106 | 16 |
14f75dcf-72ad-59cd-b062-96dbb13a8b3c | mythos_preview_multi_target_bbf14_rank23 | Mythos Preview | multi_target | BBF-14 | 23 | 105 | ARAAALEEARRRARELGGVLVEADDREAAREAVRRALEEGGRLLVVAVAETPEEVEELVRALFEAAEELGLEAEVVIHPESAAALRAAGPGGAAVLVLELRVRPA | Genie3 | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.61 | 97.5276 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank23/insilico/ | 0.68519 | 0.83645 | 0.776841 | 0.89722 | 0.535369 | 0.01948 | 0.248665 | 0.38164 | 0.554526 | 0.02047 | 0.588329 | 0.55882 | 0.538862 | 0.56289 | 0.466058 | 0.61621 | 0.444776 | 0.66146 | 0.543393 | 0.52569 | B:THR3;B:PRO4;B:ALA7;B:LEU8;B:LEU9;B:GLY10;B:GLY11;B:TYR31;B:THR32;B:ARG33;B:VAL34;B:PRO36;B:ARG109;B:VAL110 | 14 |
71ed140e-e671-571d-a726-03c567c22bad | mythos_preview_multi_target_bbf14_rank24 | Mythos Preview | multi_target | BBF-14 | 24 | 80 | SGTATAAGVELTAARAGDGLRVTATGPDGGVAVIDVALGESGVAEAGGATVSAAALDADTVGVGVVGADGSGGTATVRAA | BoltzGen | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.27 | 98.8474 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank24/insilico/ | 0.629914 | 0.69194 | 0.617823 | 0.79725 | 0.744671 | 0.69636 | 0.363014 | 0.7581 | 0.23917 | 0.66592 | 0.065496 | 0.14181 | 0.077522 | 0.73407 | 0.010645 | 0.74904 | 0 | 0.13057 | 0 | 0.14181 | B:MET1;B:THR16;B:THR18;B:ASP62;B:ASN64;B:VAL66;B:ARG68;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:LEU92;B:THR94;B:THR104;B:THR106 | 15 |
dcf8b130-bd97-5829-ae39-66b80b48d919 | mythos_preview_multi_target_bbf14_rank25 | Mythos Preview | multi_target | BBF-14 | 25 | 80 | SGTAVAAGVTLTAERRGDGLLVRAVAADGGVAEVEVALGESGVGEAGGAVVSAAALDAETVGVGVVGADGSGGTATVRAA | BoltzGen | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.92 | 85.5012 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank25/insilico/ | 0.615179 | 0.73929 | 0.63376 | 0.52317 | 0.555663 | 0.75681 | 0.227496 | 0.75212 | 0.011651 | 0.07512 | 0.346397 | 0.56129 | 0.155754 | 0.57592 | 0 | 0.82975 | 0.217582 | 0.71588 | 0.534572 | 0.79387 | B:MET1;B:THR16;B:THR18;B:ASP62;B:ASN64;B:VAL66;B:ARG68;B:THR84;B:GLN85;B:LEU86;B:ASP87;B:LEU92;B:THR94;B:THR104;B:THR106 | 15 |
938594f2-8974-5e30-9c3e-ea696bc115aa | mythos_preview_multi_target_bbf14_rank26 | Mythos Preview | multi_target | BBF-14 | 26 | 90 | SLEEIEKLFEQFKKELEKLIGEIPEETEKLLDETLEEIKKLIEQGASKEELKEVVLRLLVELLEMYADNAEARELFVEFHRRLVAVIESM | PXDesign | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.3 | 95.1821 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank26/insilico/ | 0.429742 | 0.82653 | 0.428167 | 0.78778 | 0.707452 | 0.92395 | 0.642957 | 0.94218 | 0.489254 | 0.95386 | 0.591775 | 0.78417 | 0.726825 | 0.90564 | 0.377151 | 0.95522 | 0.468079 | 0.88946 | 0.39696 | 0.96069 | B:ASN64;B:VAL66;B:ARG68;B:THR82;B:GLN85;B:LEU92;B:THR94;B:THR104 | 8 |
9dd4f67a-ca53-587b-b943-236413a2bbb9 | mythos_preview_multi_target_bbf14_rank27 | Mythos Preview | multi_target | BBF-14 | 27 | 69 | MLDFEVDVEGDPEENLRRYEEAAAELRAWYAEHGLTPSPEAEALLEAVLEEVRRRVRELLEEERRARTP | FreeBindCraft (BindCraft) | SolubleMPNN | 2 | ordered_sequence_backbone | medium | binder | 272.694976 | 8,095.95166 | 0.002636 | false | 4 | 0.33 | 96.274 | binder | 530 | 3,030 | 0.0016 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 373.657854 | both_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank27/insilico/ | 0.466163 | 0.80247 | 0.528638 | 0.74576 | 0.014542 | 0.00847 | 0.129548 | 0.42395 | 0 | 0.01294 | 0.057154 | 0.00765 | 0 | 0.01446 | 0 | 0.53141 | 0 | 0.031 | 0 | 0.04402 | B:MET1;B:PRO4;B:TRP6;B:LEU9;B:GLY10;B:GLY11;B:ARG30;B:TYR31;B:THR32;B:ARG33;B:VAL34;B:SER35;B:PRO36;B:ALA88 | 14 |
0a9b13f9-09c6-5ab6-a317-dc05e8d774fa | mythos_preview_multi_target_bbf14_rank28 | Mythos Preview | multi_target | BBF-14 | 28 | 93 | RPRRVLGVYRVETPEELLEFVRREGAGEAALRAAELAVEYAKAGDFSTAVAHMVEAFNLLGQELARRQGAEWVVDELDARGDKVVLTGRLVSR | Genie3 | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.98 | 99.3802 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank28/insilico/ | 0.637348 | 0.82115 | 0.356656 | 0.78301 | 0.207059 | 0.61719 | 0.360545 | 0.76342 | 0.218478 | 0.61279 | 0.107974 | 0.00904 | 0.037849 | 0.61367 | 0.014797 | 0.00875 | 0 | 0.01603 | 0.553337 | 0.8358 | B:MET1;B:THR18;B:TYR19;B:GLU20;B:VAL66;B:ARG68;B:GLY81;B:THR82;B:THR84;B:LEU86;B:ASP87;B:LEU92;B:THR94;B:GLY95;B:THR96;B:LYS102;B:TYR103;B:THR104;B:THR106 | 19 |
81fe8fa0-309c-58c9-b3d1-62f070fa7fe7 | mythos_preview_multi_target_bbf14_rank29 | Mythos Preview | multi_target | BBF-14 | 29 | 93 | APREVLGRYVVETPEELLEFVEEQGAGPEALEAARQAVAAAEAGDYSTAVALAVEAFLALGAELAARLGAELVVDRLDARGDRVVLEFVLLSR | Genie3 | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 2.02 | 69.6396 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank29/insilico/ | 0.668101 | 0.79155 | 0.322357 | 0.75399 | 0.177357 | 0.53221 | 0.011213 | 0.01845 | 0 | 0.12708 | 0 | 0.0859 | 0.011708 | 0.55579 | 0 | 0.01984 | 0.261644 | 0.64599 | 0 | 0.0163 | B:MET1;B:THR18;B:TYR19;B:GLU20;B:VAL66;B:ARG68;B:GLY81;B:THR82;B:THR84;B:LEU86;B:ASP87;B:LEU92;B:THR94;B:GLY95;B:THR96;B:LYS102;B:TYR103;B:THR104;B:THR106 | 19 |
5dda0e95-e2e7-528b-aba8-22b574aef94a | mythos_preview_multi_target_bbf14_rank30 | Mythos Preview | multi_target | BBF-14 | 30 | 80 | AAPPAVDYEAELERLVAELEARFGAARTDRLLELVFNDGLSPEEAAARFELSPADRARLVALLTRIRDLYEAWRAALRAA | FreeBindCraft (BindCraft) | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.76 | 73.3761 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BBF-14/mythos_preview_multi_target_bbf14_rank30/insilico/ | 0.022192 | 0.37788 | 0.535986 | 0.92112 | 0.288816 | 0.34909 | 0.577546 | 0.40142 | 0.501501 | 0.39197 | 0.593789 | 0.40408 | 0.222725 | 0.34753 | 0.370409 | 0.38958 | 0 | 0.61197 | 0.414475 | 0.37774 | B:LEU5;B:ALA7;B:LEU8;B:PRO12;B:ALA88;B:ARG109;B:VAL110 | 7 |
44802ead-933a-5163-b611-a05ad31bf738 | mythos_preview_multi_target_bhrf1_rank01 | Mythos Preview | multi_target | BHRF1 | 1 | 115 | SELLEEAVRGGEAGIRAGAEEAGRRAIEGARRAEEGIRRAVEGLAAGDFEAAERGGREAFEGGLRAEEGAREALRAAEKTGDEELIREARRGLIAAGILAGLGAILLGVAKIALK | BoltzGen | SolubleMPNN | 9 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.04 | null | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank01/insilico/ | 0.93014 | 0.96429 | 0.949835 | 0.97755 | 0.960317 | 0.96357 | 0.951544 | 0.96186 | 0.834644 | 0.88945 | 0.942455 | 0.94576 | 0.919027 | 0.95972 | 0.015706 | 0.76221 | 0.794644 | 0.92987 | 0.904414 | 0.94354 | B:ARG59;B:THR63;B:GLU66;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:ASP81;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106;B:ASN156 | 18 |
3e8a2acc-b584-5937-98eb-c685bb337c91 | mythos_preview_multi_target_bhrf1_rank02 | Mythos Preview | multi_target | BHRF1 | 2 | 115 | SPLLEKALEGGEAAIEAGDKEAGKEAIEGAREAEEGLREAVRGLREGDFERALEGGEEAAEGGYEAEEGAKRGLEAAKKTGDEELIKKANEGLIAAGILAGLGAIALGVAKLALK | BoltzGen | SolubleMPNN | 8 | ordered_sequence_backbone | none | not_expressed | null | null | null | null | 2 | 0.07 | 47.3196 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank02/insilico/ | 0.929826 | 0.94803 | 0.939171 | 0.96288 | 0.955811 | 0.95805 | 0.948696 | 0.95473 | 0.845462 | 0.89339 | 0.948045 | 0.9426 | 0.894274 | 0.93073 | 0.865142 | 0.92303 | 0.802224 | 0.95921 | 0.887764 | 0.97061 | B:ARG59;B:ASN60;B:THR63;B:GLU66;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:ASP81;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 18 |
f34386b3-c6f6-506e-ab86-6cc4eb341884 | mythos_preview_multi_target_bhrf1_rank03 | Mythos Preview | multi_target | BHRF1 | 3 | 88 | SKAEGQKGVLSAEIGVGVALIRVGVAKIVLRSAPGEESQRLLEEAEERLRRAEALLEQARAAYEAGKGAEALALGTQAFEAAGGKGGL | BoltzGen | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.56 | 92.9264 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank03/insilico/ | 0.927201 | 0.95691 | 0.933404 | 0.97724 | 0.942649 | 0.90047 | 0.940203 | 0.97707 | 0.816783 | 0.90829 | 0.959787 | 0.91933 | 0.928141 | 0.94307 | 0.84831 | 0.95143 | 0.764424 | 0.86581 | 0.884025 | 0.95588 | B:GLU55;B:ARG59;B:ASN60;B:THR63;B:THR67;B:PHE71;B:HIS74;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 16 |
7079f821-671d-57e5-b233-53ebfc3d08d0 | mythos_preview_multi_target_bhrf1_rank04 | Mythos Preview | multi_target | BHRF1 | 4 | 88 | SEEKGKRGVLSAEIGVGVALIRVGVARIVLRAEPGPESEELLREAEERLREAERLLEEAKEAYEAGKGEEAYELGTRAFEAAGGKGGL | BoltzGen | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.43 | 60.5429 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank04/insilico/ | 0.927932 | 0.96893 | 0.926715 | 0.95721 | 0.942619 | 0.89193 | 0.93677 | 0.9774 | 0.338989 | 0.03949 | 0.954139 | 0.89627 | 0.923644 | 0.92726 | 0.843322 | 0.85646 | 0.761444 | 0.87516 | 0.888479 | 0.95316 | B:GLU55;B:ARG59;B:ASN60;B:THR63;B:THR67;B:HIS74;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 15 |
9fb66ad4-a5b5-5768-97fd-e44da09c04c8 | mythos_preview_multi_target_bhrf1_rank05 | Mythos Preview | multi_target | BHRF1 | 5 | 90 | SEEKEELIKGAEKALEKVIEVALSKPAKDVKENNIKIGAVIASIGFLLDIELAKTLEEAKEYARRFVEFVRESELPEIREIAPEIEKLLL | Proteina-Complexa | SolubleMPNN | 1 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 0.2 | 82.317 | binder | 29 | 2,920 | 0.000086 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | twist_only_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank05/insilico/ | 0.923966 | 0.93686 | 0.935893 | 0.94899 | 0.951114 | 0.90536 | 0.942299 | 0.913 | 0.824725 | 0.88939 | 0.948088 | 0.87178 | 0.919885 | 0.90985 | 0.887193 | 0.83647 | 0.786329 | 0.84532 | 0.896538 | 0.93094 | B:ASN60;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:HIS91;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:ASN156 | 18 |
38f83019-9e3d-51d0-b7d8-ae4eb3ce9ca0 | mythos_preview_multi_target_bhrf1_rank06 | Mythos Preview | multi_target | BHRF1 | 6 | 105 | MSVVSKYVAAAILVVGAEINLDLAEKSTGEKAIKYLEEALDALEAALELLKEILEELPEELARALLERLREVAERAVELAKKLNAPEELIRRAERLAREAEELLE | Proteina-Complexa | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.37 | 83.8049 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank06/insilico/ | 0.926943 | 0.88636 | 0.933532 | 0.92501 | 0.945197 | 0.89539 | 0.941268 | 0.89954 | 0.860942 | 0.8869 | 0.947457 | 0.82027 | 0.936932 | 0.88869 | 0.862777 | 0.89379 | 0.803286 | 0.85136 | 0.890279 | 0.83191 | B:ARG59;B:ASN60;B:THR63;B:PHE64;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:THR75;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 21 |
49062550-67fa-5ff8-99f6-6135c0bb4bec | mythos_preview_multi_target_bhrf1_rank07 | Mythos Preview | multi_target | BHRF1 | 7 | 82 | MEEAKEKFDKGVELIEEGKYIEGLELIAEGIKLLRKSDSPEAAVLITAARVIMIGTIEQLRLQKADPELIEKLEEILKSTLE | Proteina-Complexa | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 0.53 | 96.1841 | binder | 2.3 | 5,950 | 0.000014 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 14.569621 | twist_only_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank07/insilico/ | 0.915282 | 0.93816 | 0.913168 | 0.93446 | 0.947482 | 0.93311 | 0.932928 | 0.96757 | 0.796142 | 0.84156 | 0.923484 | 0.89322 | 0.904514 | 0.88437 | 0.014346 | 0.03166 | 0.765908 | 0.82324 | 0.8684 | 0.9383 | B:ILE56;B:ASN60;B:THR63;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:THR75;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106;B:ASN156 | 21 |
7f70b003-bfe5-5af6-8624-07c428f3e55a | mythos_preview_multi_target_bhrf1_rank08 | Mythos Preview | multi_target | BHRF1 | 8 | 111 | SAEELREEAIRLLREALELIDELLKIENPPEERIEELIRLVEEGLELAREALKLADLSDTSPKSVAKYVALQLTIIGAEISLELFKKNPRNKQLLEELRLDLEALLSLLEE | Proteina-Complexa | SolubleMPNN | 3 | ordered_sequence_backbone | medium | binder | 5.133312 | 13,666.05957 | 0.00007 | false | 2 | 0.03 | null | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 4.932068 | adaptyv_only_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank08/insilico/ | 0.917116 | 0.93589 | 0.919554 | 0.93359 | 0.941176 | 0.93104 | 0.925051 | 0.93571 | 0.823478 | 0.81508 | 0.934924 | 0.91589 | 0.916828 | 0.93932 | 0.861833 | 0.92005 | 0.778003 | 0.82506 | 0.876231 | 0.91183 | B:ASN60;B:THR63;B:THR67;B:ARG70;B:HIS74;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:ASP94;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 18 |
2a82fe83-bbbb-5726-a8e9-ec5b776b85d6 | mythos_preview_multi_target_bhrf1_rank09 | Mythos Preview | multi_target | BHRF1 | 9 | 86 | SMKEEYIEEVRRIVDRAVEELERLAEEHKEDRKKKLAAETAIGVVRLAGGVALLVIKRKPEEGEEAIELVRRAAERAIRNAKEGLL | BoltzGen | SolubleMPNN | 1 | ordered_sequence_backbone | medium | binder | 2.010443 | null | null | false | 4 | 0.39 | 36.4917 | binder | 0.13 | 105,700 | 0.000014 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 0.233666 | both_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank09/insilico/ | 0.907169 | 0.89023 | 0.925936 | 0.91617 | 0.934943 | 0.88242 | 0.932076 | 0.90705 | 0.799281 | 0.8627 | 0.957263 | 0.8637 | 0.917386 | 0.89617 | 0.866759 | 0.84984 | 0.738427 | 0.88074 | 0.865573 | 0.91491 | B:ILE56;B:ARG59;B:ASN60;B:THR63;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102 | 16 |
9a9128eb-cd6d-5d69-87ae-c2b87a017965 | mythos_preview_multi_target_bhrf1_rank10 | Mythos Preview | multi_target | BHRF1 | 10 | 90 | SSEKEELIKGAREALKLVIEVALSEEAKDVKENNQKIGEVIASIGYLLDIELAKTLEEARKHAREFVDFVRESRIPEVREIAPEVEKLLL | Proteina-Complexa | SolubleMPNN | 1 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.07 | 37.8351 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank10/insilico/ | 0.926487 | 0.94949 | 0.927226 | 0.94808 | 0.94541 | 0.84673 | 0.94076 | 0.94745 | 0.825751 | 0.94854 | 0.939286 | 0.89054 | 0.918598 | 0.88473 | 0.805006 | 0.81782 | 0.792133 | 0.86646 | 0.885997 | 0.83658 | B:ASN60;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:HIS91;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:ASN156 | 18 |
ab615299-f67c-5db9-a2c9-0ce07be91863 | mythos_preview_multi_target_bhrf1_rank11 | Mythos Preview | multi_target | BHRF1 | 11 | 111 | SMEEARRKAIEYLEEALELIEEIEEMENPPEELIEKLIELVEKGLRYAEEALRLTPRTDTSPQAVAREVARRLVIIGARISLELFKKNPKSRTLLRELKLDLEALLEILRE | Proteina-Complexa | SolubleMPNN | 1 | ordered_sequence_backbone | medium | binder | 1.845077 | 5,430.698242 | 0.00001 | false | 2 | 0.02 | null | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 1.219991 | adaptyv_only_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank11/insilico/ | 0.893119 | 0.95856 | 0.91282 | 0.95825 | 0.937084 | 0.95696 | 0.923463 | 0.97598 | 0.811736 | 0.8856 | 0.934329 | 0.86404 | 0.901589 | 0.79257 | 0.848382 | 0.79999 | 0.768528 | 0.83687 | 0.871417 | 0.96806 | B:ARG59;B:ASN60;B:THR63;B:THR67;B:ARG70;B:HIS74;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:ASP94;B:SER96;B:LEU97;B:GLY98;B:ARG99;B:ALA102;B:TRP106;B:ASN156 | 21 |
f3905bb0-1144-5f71-91e6-1c41a9276e2a | mythos_preview_multi_target_bhrf1_rank12 | Mythos Preview | multi_target | BHRF1 | 12 | 86 | SMKERYIEEIRRITDEAVEELEKYAEEHKEDKKKKLAAETAIGVVRIAGGVGILVVRRDPSEGEAAIELVRRAAERAIKNAKEGKL | BoltzGen | SolubleMPNN | 1 | ordered_sequence_backbone | medium | binder | 2.998304 | null | null | false | 4 | 0.55 | 15.0085 | binder | 2.8 | 7,660 | 0.000021 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 7.104106 | both_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank12/insilico/ | 0.902497 | 0.93385 | 0.91673 | 0.93424 | 0.931534 | 0.89724 | 0.921682 | 0.90801 | 0.011989 | 0.03232 | 0.95595 | 0.88843 | 0.890469 | 0.84873 | 0.845711 | 0.80377 | 0.741392 | 0.91861 | 0.860371 | 0.92649 | B:ILE56;B:ARG59;B:ASN60;B:THR63;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102 | 16 |
d090d15b-ffd2-544e-a1f1-42e6b0212c78 | mythos_preview_multi_target_bhrf1_rank13 | Mythos Preview | multi_target | BHRF1 | 13 | 72 | SHAAHVAATTIEAIGAGIDEGLKNKGKPELAREEGEEAARRVAEEALEKGLVTEEEAERAVEAGGRAAEGVA | BoltzGen | SolubleMPNN | 2 | ordered_sequence_backbone | medium | binder | 41.227994 | 8,234.647461 | 0.000319 | false | 2 | 1.67 | 99.7659 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 59.380971 | adaptyv_only_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank13/insilico/ | 0.913009 | 0.92108 | 0.92622 | 0.92647 | 0.949989 | 0.93337 | 0.927811 | 0.91641 | 0.800105 | 0.84196 | 0.950848 | 0.87288 | 0.927041 | 0.93392 | 0.852652 | 0.90507 | 0.763509 | 0.87974 | 0.849675 | 0.92939 | B:ARG59;B:ASN60;B:THR63;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:ASP81;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 17 |
9acfeec0-343a-510c-9298-b54d7f7ff961 | mythos_preview_multi_target_bhrf1_rank14 | Mythos Preview | multi_target | BHRF1 | 14 | 90 | MEAARRGREAGRRGEAAETAEEALRAAEEGIRAAEAAEDPEERLEAARGALRAALAAVRKGEGELAIRAVGLAVRALGLELDAELELGRL | BoltzGen | SolubleMPNN | 1 | ordered_sequence_backbone | none | not_expressed | null | null | null | null | 2 | 0.76 | 77.7065 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank14/insilico/ | 0.889337 | 0.9705 | 0.921942 | 0.93619 | 0.943614 | 0.89314 | 0.937373 | 0.88558 | 0.809946 | 0.82729 | 0.944891 | 0.85895 | 0.861565 | 0.87212 | 0.782813 | 0.63996 | 0.773096 | 0.8634 | 0.884175 | 0.91603 | B:ARG59;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:ASP81;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 15 |
8a82f476-17e1-5d4a-b053-3ff2699c7b1f | mythos_preview_multi_target_bhrf1_rank15 | Mythos Preview | multi_target | BHRF1 | 15 | 72 | SREQLKKEAEADLEAAREALEELPKDSPEHKLAERLLREAEEALKQGNYLEAGILAGLVLLVYGVYKAVSKK | Proteina-Complexa | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.03 | null | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank15/insilico/ | 0.911789 | 0.94356 | 0.907672 | 0.84858 | 0.931822 | 0.89095 | 0.932083 | 0.9529 | 0.777819 | 0.84556 | 0.932106 | 0.8717 | 0.913361 | 0.9075 | 0.843349 | 0.87935 | 0.772262 | 0.94198 | 0.851852 | 0.96492 | B:ILE56;B:THR63;B:GLU66;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:THR75;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:ASN156 | 20 |
0326ac71-c6bc-5abb-941d-2a21f0bdeac5 | mythos_preview_multi_target_bhrf1_rank16 | Mythos Preview | multi_target | BHRF1 | 16 | 72 | SRAELEAAARADLAAARAALAELPADSAEAALARRLLAEAEAAYRAGDYLTAGILAGLVLLVYGVYKAVKAS | Proteina-Complexa | SolubleMPNN | 1 | ordered_sequence_backbone | none | not_expressed | null | null | null | null | 2 | null | null | not_measured | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | false | null | adaptyv_only_tested | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank16/insilico/ | 0.917287 | 0.92425 | 0.914907 | 0.84675 | 0.934109 | 0.8764 | 0.933223 | 0.92264 | 0.686379 | 0.73135 | 0.942196 | 0.8804 | 0.894565 | 0.77935 | 0.834096 | 0.82324 | 0.743823 | 0.90877 | 0.866459 | 0.90324 | B:ILE56;B:THR63;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:THR75;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:ASN156 | 19 |
32425e8f-bb7b-51ca-96e1-f8c337eb83a6 | mythos_preview_multi_target_bhrf1_rank17 | Mythos Preview | multi_target | BHRF1 | 17 | 82 | MEKALELFDEGVRLIEEGRYVEGLRLIGEAIRLLRESDSPRAAVLITAAKLIMIGTIEQLRLEGADPELIEELERILRETLE | Proteina-Complexa | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.06 | 39.0635 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank17/insilico/ | 0.899492 | 0.79188 | 0.927833 | 0.89866 | 0.939788 | 0.91699 | 0.932896 | 0.87293 | 0.786921 | 0.78876 | 0.947921 | 0.82057 | 0.012407 | 0.70567 | 0.702196 | 0.71886 | 0.7689 | 0.8571 | 0.868221 | 0.93701 | B:ILE56;B:ASN60;B:THR63;B:GLU66;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:THR75;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106;B:ASN156 | 22 |
3bf95c1f-d390-56a3-a997-9d72be366107 | mythos_preview_multi_target_bhrf1_rank18 | Mythos Preview | multi_target | BHRF1 | 18 | 84 | SSLSHKELLQAIGRVIRLIGELEDLRLRKRKGADKEELLEELEELKEEIEEEIEELKERDPELAKVFEKVLERVEELIEEVKKE | BoltzGen | SolubleMPNN | 1 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.04 | null | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank18/insilico/ | 0.910228 | 0.90596 | 0.910777 | 0.90403 | 0.926591 | 0.92661 | 0.914923 | 0.94953 | 0.752351 | 0.82128 | 0.926884 | 0.90775 | 0.916305 | 0.89598 | 0.797372 | 0.81929 | 0.733004 | 0.83295 | 0.859752 | 0.91585 | B:ILE56;B:ASN60;B:GLU62;B:THR63;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:GLU76;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:SER96;B:GLY98;B:ARG99;B:ALA102 | 17 |
776884f4-1477-51ef-90be-8c74e115e7d7 | mythos_preview_multi_target_bhrf1_rank19 | Mythos Preview | multi_target | BHRF1 | 19 | 90 | MAAAEAGRAAGAAGEAAETAEEALAAAERGIAAAEAAEDPAERLEAARGALRGALAAVRKGEGELAIRAVGLTVRALGLILDAELELGKL | BoltzGen | SolubleMPNN | 1 | ordered_sequence_backbone | none | not_expressed | null | null | null | null | 2 | 1.7 | 86.9473 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank19/insilico/ | 0.866093 | 0.9665 | 0.902596 | 0.91174 | 0.943468 | 0.9018 | 0.925986 | 0.9371 | 0.814218 | 0.84664 | 0.48445 | 0.04212 | 0.881596 | 0.71434 | 0.761213 | 0.90236 | 0.735804 | 0.84918 | 0.866247 | 0.93881 | B:ARG59;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:ASP81;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 15 |
306093a4-a353-5636-8137-a7c72c0c2113 | mythos_preview_multi_target_bhrf1_rank20 | Mythos Preview | multi_target | BHRF1 | 20 | 60 | MLKSVKEVIEEAKKIEGYEEEIKEVEELAERAEKSTGTKGAVLETAAALRAIGIILDAEL | Proteina-Complexa | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.6 | 95.6577 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank20/insilico/ | 0.897169 | 0.88871 | 0.90911 | 0.87336 | 0.936578 | 0.90717 | 0.891979 | 0.64046 | 0.731829 | 0.6332 | 0.915669 | 0.64903 | 0.881467 | 0.9065 | 0.795972 | 0.64573 | 0.756603 | 0.8955 | 0.786173 | 0.63006 | B:ASN60;B:GLU62;B:THR63;B:GLU66;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:THR75;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP103;B:TRP106;B:ASN156 | 23 |
8005d024-5776-5085-b0db-82de9224c06f | mythos_preview_multi_target_bhrf1_rank21 | Mythos Preview | multi_target | BHRF1 | 21 | 60 | MLKSVKEVIEEAEKIEGYEEEIKEVRELAEEAERSSGTRGAVLETAAALRAIGIILDAEL | Proteina-Complexa | SolubleMPNN | 2 | ordered_sequence_backbone | medium | binder | 30.998861 | null | null | false | 4 | 1.19 | 95.0831 | binder | 1.23 | 8,100 | 0.00001 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 87.849638 | both_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank21/insilico/ | 0.893792 | 0.91876 | 0.910113 | 0.92893 | 0.937457 | 0.85428 | 0.896511 | 0.64006 | 0.723766 | 0.65191 | 0.922261 | 0.65009 | 0.890174 | 0.65465 | 0.793617 | 0.65069 | 0.734215 | 0.89506 | 0.800462 | 0.63766 | B:ASN60;B:GLU62;B:THR63;B:GLU66;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:THR75;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP103;B:TRP106;B:ASN156 | 23 |
7f7878ee-0993-5854-81d9-f7b0bea24ede | mythos_preview_multi_target_bhrf1_rank22 | Mythos Preview | multi_target | BHRF1 | 22 | 105 | DPLKRAIEAVERLIEKFEEALEKEEISEEDVEELKRALEEAIEAVMEAFRSFEEMSNEELSKFVAIHILLAAVGFELERPSRERLERALEMAKAALELLKELEES | Proteina-Complexa | SolubleMPNN | 1 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.02 | null | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank22/insilico/ | 0.906167 | 0.89807 | 0.919879 | 0.88403 | 0.933919 | 0.96401 | 0.923832 | 0.86688 | 0.794796 | 0.81762 | 0.909087 | 0.85027 | 0.895424 | 0.90721 | 0.042837 | 0.01811 | 0.731329 | 0.88331 | 0.85664 | 0.84056 | B:ILE56;B:ARG59;B:ASN60;B:THR63;B:PHE64;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 20 |
6fbc8e21-7105-5618-8c8f-1c80ed5142c4 | mythos_preview_multi_target_bhrf1_rank23 | Mythos Preview | multi_target | BHRF1 | 23 | 84 | SSLSHQELLEAIGRVIRFIGELIDLELQVKKGADKEEVLEQLEKLIEEIRKAIEEYREKDPELAKVFEKVLKNAEKLKKEVEAL | BoltzGen | SolubleMPNN | 1 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.1 | 51.8585 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank23/insilico/ | 0.910738 | 0.91946 | 0.911159 | 0.96288 | 0.932162 | 0.86467 | 0.913861 | 0.95531 | 0.80348 | 0.89546 | 0.929058 | 0.90444 | 0.915005 | 0.90885 | 0.840282 | 0.90113 | 0.762177 | 0.86851 | 0.865271 | 0.86283 | B:ILE56;B:ASN60;B:GLU62;B:THR63;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:GLU76;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:SER96;B:GLY98;B:ARG99;B:ALA102 | 17 |
50db2657-d4da-5dd5-b3e5-673c4917d292 | mythos_preview_multi_target_bhrf1_rank24 | Mythos Preview | multi_target | BHRF1 | 24 | 75 | SEEERIKRLLEETRELIKEILSIADELSHEELIEAVALAIEWAGLEFEFEQGRLTLEEVEALKRRVEEFKERVLK | PXDesign | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.33 | 94.7301 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank24/insilico/ | 0.892967 | 0.9344 | 0.902863 | 0.95283 | 0.930863 | 0.91798 | 0.904373 | 0.92843 | 0.761762 | 0.89082 | 0.728272 | 0.06179 | 0.912844 | 0.88482 | 0.648462 | 0.65955 | 0.708405 | 0.85508 | 0.840882 | 0.95917 | B:ILE56;B:ARG59;B:ASN60;B:THR63;B:PHE64;B:GLU66;B:THR67;B:ARG70;B:GLU76;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 17 |
93742662-d6ec-57a6-84b5-c5d4b233093d | mythos_preview_multi_target_bhrf1_rank25 | Mythos Preview | multi_target | BHRF1 | 25 | 105 | SLLEKAIEATEELIATLERALAAEEITEEQVEELKEALEEAIRAVMAFFKSQEKMSNEQLSKVIAIHILLASVGLQLEKPSRERLEEALGDARAVLDLLKELKKE | Proteina-Complexa | SolubleMPNN | 1 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 0.02 | null | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank25/insilico/ | 0.897179 | 0.92494 | 0.916167 | 0.88433 | 0.931233 | 0.93057 | 0.913484 | 0.92716 | 0.013807 | 0.03644 | 0.933611 | 0.8634 | 0.890832 | 0.87766 | 0.785804 | 0.76463 | 0.729318 | 0.85452 | 0.86829 | 0.82467 | B:ILE56;B:ARG59;B:ASN60;B:THR63;B:PHE64;B:GLU66;B:THR67;B:ARG70;B:HIS74;B:GLU76;B:ASP81;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 20 |
8295efed-7d0c-55ce-87eb-4468d161b670 | mythos_preview_multi_target_bhrf1_rank26 | Mythos Preview | multi_target | BHRF1 | 26 | 75 | SMREEIERILRESGELVKELLSKSDEMSHEQRLRVIALAIRYAGAEFDFRQGRLSLEEARELLREIKELKEEVEK | PXDesign | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 0.05 | 41.1879 | binder | 2.27 | 4,410 | 0.00001 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | twist_only_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank26/insilico/ | 0.886923 | 0.95598 | 0.903186 | 0.9544 | 0.933295 | 0.93777 | 0.916668 | 0.93945 | 0.788583 | 0.85662 | 0.920962 | 0.91885 | 0.924638 | 0.93052 | 0.84011 | 0.93297 | 0.739249 | 0.92503 | 0.837809 | 0.90384 | B:ILE56;B:ASN60;B:THR63;B:PHE64;B:GLU66;B:THR67;B:ARG70;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 15 |
0fc4996c-a0e0-546a-b689-30cbdb6ff6e7 | mythos_preview_multi_target_bhrf1_rank27 | Mythos Preview | multi_target | BHRF1 | 27 | 75 | SDIAKAAIKLTAAEIIFIGAEIDKEVSEEIIKEIKELFEEAIKLLEKAGDKEGVEEAKKRKEEIEKKIKELQEKL | PXDesign | SolubleMPNN | 1 | ordered_sequence_backbone | medium | binder | 0.675881 | 14,798.568359 | 0.00001 | false | 2 | 0.62 | 34.674 | binder | 0.68 | 75,600 | 0.000052 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | true | 0.921954 | both_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank27/insilico/ | 0.899572 | 0.97699 | 0.906086 | 0.98533 | 0.928509 | 0.84067 | 0.889782 | 0.87953 | 0.745683 | 0.92722 | 0.897408 | 0.88118 | 0.904736 | 0.96737 | 0.781411 | 0.91955 | 0.734174 | 0.8136 | 0.767842 | 0.88351 | B:ASN60;B:THR63;B:THR67;B:ARG70;B:PHE71;B:HIS74;B:GLU76;B:SER84;B:VAL85;B:GLU88;B:ILE89;B:ARG92;B:SER96;B:GLY98;B:ARG99;B:ALA102;B:TRP106 | 17 |
aafa7f6a-8f47-539e-b18c-88e5f1260146 | mythos_preview_multi_target_bhrf1_rank28 | Mythos Preview | multi_target | BHRF1 | 28 | 82 | HMTKEEKIEEIKKLVSQLNSPSLMKLVDEFEKANPTDEELDRLLESAKRAVEAQKGTPREFAVAETALALNLIGVLLDKELE | Proteina-Complexa | Caliby (SolubleCaliby) | 0 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.29 | 80.5593 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank28/insilico/ | 0.898767 | 0.92982 | 0.912737 | 0.89369 | 0.932285 | 0.90426 | 0.914042 | 0.89694 | 0.741297 | 0.86745 | 0.924329 | 0.91498 | 0.920304 | 0.87676 | 0.160328 | 0.02035 | 0.69699 | 0.91433 | 0.822208 | 0.84799 | A:ILE56;A:ARG59;A:ASN60;A:GLU62;A:THR63;A:PHE64;A:GLU66;A:THR67;A:ARG70;A:PHE71;A:HIS74;A:THR75;A:GLU76;A:HIS77;A:LEU80;A:ASP81;A:SER84;A:VAL85;A:GLU88;A:ILE89;A:PHE90;A:ARG92;A:GLY93;A:ASP94;A:PRO95;A:SER96;A:LEU97;A:GLY98;A:ARG99;A:LEU101;A:ALA102;A:TRP103;A:TRP106;A:ASN156 | 34 |
867397bc-c3cb-54c2-9061-7acb42f4b410 | mythos_preview_multi_target_bhrf1_rank29 | Mythos Preview | multi_target | BHRF1 | 29 | 84 | MADELLERAKKLVEQGKADLERGQTLMDEGIATGDRKLLNQGIADILRGIGDMIEAYLFAKKAIELGGNKEEAQRIMKEAGGPV | BoltzGen | Caliby (SolubleCaliby) | 0 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.39 | 73.0977 | non_binder | null | null | null | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank29/insilico/ | 0.864442 | 0.87557 | 0.867857 | 0.8069 | 0.92178 | 0.88186 | 0.89671 | 0.94143 | 0.76171 | 0.85826 | 0.933211 | 0.77546 | 0.888152 | 0.83785 | 0.835239 | 0.8317 | 0.71957 | 0.77283 | 0.837938 | 0.88557 | A:ILE56;A:ARG59;A:ASN60;A:THR63;A:PHE64;A:GLU66;A:THR67;A:ARG70;A:PHE71;A:HIS74;A:THR75;A:GLU76;A:ASP81;A:SER84;A:VAL85;A:GLU88;A:ILE89;A:HIS91;A:SER96;A:LEU97;A:GLY98;A:ARG99;A:LEU101;A:ALA102;A:TRP103;A:TRP106;A:ASP155;A:ASN156;A:ILE157 | 29 |
8ee00e2e-a865-52ba-bdb0-cd957931c8d1 | mythos_preview_multi_target_bhrf1_rank30 | Mythos Preview | multi_target | BHRF1 | 30 | 78 | DPVQRLLDAIRAGDREAALKALDEYRKQMLAEVPELDTPKVRELFEELRKAIEAGNPLEAEINLGILDIVYAVAKRYP | Proteina-Complexa | Caliby (SolubleCaliby) | 0 | ordered_sequence_backbone | none | not_expressed | null | null | null | null | 2 | 0.78 | 97.7594 | binder | 2.49 | 4,020 | 0.00001 | not_tested | null | not_tested | null | non_binder | null | not_tested | null | not_tested | null | false | null | twist_only_bind | not_tested | null | not_tested | null | designs/BHRF1/mythos_preview_multi_target_bhrf1_rank30/insilico/ | 0.900556 | 0.78915 | 0.920912 | 0.80791 | 0.928179 | 0.82168 | 0.930274 | 0.87154 | 0.795866 | 0.82609 | 0.935298 | 0.75701 | 0.917746 | 0.82833 | 0.828423 | 0.748 | 0.771341 | 0.80759 | 0.863604 | 0.8226 | A:ILE56;A:ARG59;A:ASN60;A:GLU62;A:THR63;A:PHE64;A:GLU66;A:THR67;A:ARG70;A:PHE71;A:HIS74;A:THR75;A:GLU76;A:ASP81;A:SER84;A:VAL85;A:GLU88;A:ILE89;A:ARG92;A:GLY93;A:ASP94;A:PRO95;A:SER96;A:LEU97;A:GLY98;A:ARG99;A:LEU101;A:ALA102;A:TRP103;A:TRP106;A:ASN156;A:ILE157 | 32 |
8b61af49-291b-5226-b8d7-10f06d4a5164 | mythos_preview_multi_target_cas9_rank01 | Mythos Preview | multi_target | Cas9 | 1 | 80 | DITEFLVKTVEDILSLDPVSQKDAVKAELKAVKLLLEQYPDNSAVQLAYKKLKQAAETPDIGEREKILEELLKELKEMLK | PXDesign | SolubleMPNN | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 0.77 | 97.4333 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank01/insilico/ | 0 | 0.00612 | 0.588638 | 0.51475 | 0.751233 | 0.7974 | 0.016457 | 0.48118 | null | null | 0 | 0.0069 | 0 | 0.0099 | 0 | 0.00661 | 0.392163 | 0.54518 | 0 | 0.00626 | B:GLU57;B:ALA61;B:GLN774;B:GLN807;B:SER1106;B:LYS1107;B:GLU1108;B:SER1136;B:PRO1137;B:THR1138;B:LYS1200;B:TYR1201;B:ALA1215;B:GLU1219;B:GLN1221;B:HIS1311;B:THR1314;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:THR1330;B:ARG1333;B:ARG1335 | 26 |
6192ccd3-f45b-56c3-b795-d3f009aa304a | mythos_preview_multi_target_cas9_rank02 | Mythos Preview | multi_target | Cas9 | 2 | 80 | DIVDFLIETVKEILSLDPVTMRDEIRATLKSVELLYKKYPNNEAVRLALRELQRAAETPDIGEREKILENLYKKLEELKK | PXDesign | Caliby (SolubleCaliby) | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 0.1 | 75.677 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank02/insilico/ | 0 | 0.00588 | 0.499758 | 0.48711 | 0.618037 | 0.74102 | 0.518411 | 0.52629 | null | null | 0 | 0.00569 | 0 | 0.10897 | 0 | 0.00473 | 0.387798 | 0.52635 | 0 | 0.00699 | B:GLU57;B:ALA61;B:THR770;B:GLN774;B:GLN807;B:SER1106;B:LYS1107;B:GLU1108;B:SER1136;B:PRO1137;B:THR1138;B:LYS1200;B:TYR1201;B:ALA1215;B:GLU1219;B:GLN1221;B:HIS1311;B:THR1314;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:THR1330;B:ARG1333;B:ARG1335 | 27 |
99a6868f-d258-5c92-bf48-ad4eaf5b726f | mythos_preview_multi_target_cas9_rank03 | Mythos Preview | multi_target | Cas9 | 3 | 80 | EITDFLVKTLEDILSLDPVTMRDAVRATLRSFKLLEKKYPNNEAVRLAVRELERAVQTPDIGEREKILEEMLKKLKELSK | PXDesign | Caliby (SolubleCaliby) | 4 | ordered_sequence_backbone | null | not_tested | null | null | null | null | null | 0.06 | 33.4526 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | twist_only_tested | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank03/insilico/ | 0 | 0.00458 | 0.50836 | 0.48117 | 0.67867 | 0.70274 | 0 | 0.15215 | null | null | 0 | 0.00635 | 0 | 0.1408 | 0 | 0.00659 | 0 | 0.00731 | 0 | 0.00601 | B:GLU57;B:ALA61;B:GLU766;B:ASN767;B:GLN768;B:THR769;B:GLN774;B:GLN807;B:ASN808;B:SER1106;B:LYS1107;B:GLU1108;B:SER1136;B:PRO1137;B:THR1138;B:LYS1200;B:TYR1201;B:ALA1215;B:GLU1219;B:GLN1221;B:HIS1311;B:THR1314;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:THR1330;B:ARG1333;B:ARG1335 | 31 |
6383307e-abe2-5266-b9d8-9e28da931524 | mythos_preview_multi_target_cas9_rank04 | Mythos Preview | multi_target | Cas9 | 4 | 80 | DLTEFLVETVKDILSLDPVSMKDAVKAELKAIGLLLKQYPDNTSVRLAYSKLSEAAQTPDIGKMVEILEELLKELEEMLK | PXDesign | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.48 | 93.8994 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank04/insilico/ | 0 | 0.00616 | 0.488675 | 0.46742 | 0.694481 | 0.70558 | 0.496957 | 0.49428 | null | null | 0 | 0.01746 | 0 | 0.08766 | 0 | 0.00579 | 0.379715 | 0.49747 | 0 | 0.00605 | B:GLU57;B:ALA61;B:THR770;B:GLN774;B:THR804;B:GLN807;B:ASN808;B:SER1106;B:LYS1107;B:GLU1108;B:SER1136;B:PRO1137;B:THR1138;B:LYS1200;B:TYR1201;B:ALA1215;B:GLU1219;B:GLN1221;B:HIS1311;B:THR1314;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:THR1330;B:ARG1333;B:ARG1335 | 29 |
502fefd4-ee2f-5162-978f-b2c4ab5ab1b5 | mythos_preview_multi_target_cas9_rank05 | Mythos Preview | multi_target | Cas9 | 5 | 71 | MLVARAETLYNEGHLENAALLYESAAEVGENLGGDEKKVAELYEKAAYLYELAGNLEKAKELFKKAKELLK | Proteina-Complexa | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.35 | 93.8691 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank05/insilico/ | 0 | 0.58659 | 0.100247 | 0.53985 | 0.556116 | 0.85445 | 0 | 0.11691 | null | null | 0.108078 | 0.00696 | 0 | 0.10217 | 0 | 0.00657 | 0.226184 | 0.52335 | 0 | 0.0062 | B:THR769;B:THR770;B:GLN774;B:ARG976;B:GLU977;B:LYS1107;B:SER1136;B:PRO1137;B:THR1138;B:VAL1139;B:LYS1200;B:GLU1219;B:HIS1311;B:LEU1318;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:ARG1333;B:ARG1335 | 22 |
f6a500e3-ddf1-5bcb-9868-890237a9afcc | mythos_preview_multi_target_cas9_rank06 | Mythos Preview | multi_target | Cas9 | 6 | 71 | MLVERAQILYNEGHLENAALLYESAALLGEELGGDERKTAELYETAAYLYELAGNKEKAEELFKRAKELLK | Proteina-Complexa | SolubleMPNN | 0 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.07 | 71.8744 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank06/insilico/ | 0.172449 | 0.54151 | 0.142001 | 0.70412 | 0.674098 | 0.88214 | 0 | 0.26209 | null | null | 0.081313 | 0.00656 | 0 | 0.00897 | 0 | 0.00668 | 0 | 0.00888 | 0 | 0.00714 | A:ASN14;A:SER15;A:LEU52;A:GLU57;A:LYS65;A:GLY365;A:GLY366;A:ALA367;A:GLU370;A:GLU371;A:ASN767;A:GLN768;A:THR769;A:THR770;A:GLN771;A:GLN774;A:THR804;A:GLN807;A:ARG976;A:GLU977;A:ILE978;A:ASN979;A:HIS983;A:LYS1096;A:SER1106;A:LYS1107;A:GLU1108;A:SER1109;A:SER1136;A:PRO1137;A:THR1138;A:LYS1200;A:TYR1201;A:MET1213;A:ALA121... | 56 |
15fca0fe-0d09-50a5-8731-f2172d3e0e27 | mythos_preview_multi_target_cas9_rank07 | Mythos Preview | multi_target | Cas9 | 7 | 80 | DLTEFLVETVKDILSLDPVSMKDAVKAELKAIGLLKKQYPENLSVQLAYEKLSEAAKTPDIGKMVEILEELLKELEEMLK | PXDesign | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.35 | 95.348 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank07/insilico/ | 0 | 0.00609 | 0.347479 | 0.77281 | 0.687111 | 0.8228 | 0 | 0.50636 | null | null | 0 | 0.00694 | 0 | 0.123 | 0 | 0.00577 | 0.388772 | 0.64088 | 0 | 0.00592 | B:GLU57;B:ALA61;B:GLN774;B:GLN807;B:SER1106;B:LYS1107;B:GLU1108;B:SER1136;B:THR1138;B:LYS1200;B:TYR1201;B:ALA1215;B:GLU1219;B:GLN1221;B:HIS1311;B:THR1314;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:THR1330;B:ARG1333;B:ARG1335 | 25 |
182b5d1a-32d5-58e5-a69f-7662f16f28bd | mythos_preview_multi_target_cas9_rank08 | Mythos Preview | multi_target | Cas9 | 8 | 80 | SLTQFLIDTVEDILSLDPISMEDAVKAELKAVEILAKQYPDNEAIQYALKKLKEAAETPDVGKREEILKELLKKLKEMAK | PXDesign | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.24 | 96.8205 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank08/insilico/ | 0 | 0.00604 | 0.329291 | 0.76261 | 0.732645 | 0.92811 | 0 | 0.33399 | null | null | 0.010835 | 0.52919 | 0 | 0.01 | 0 | 0.00684 | 0 | 0.00633 | 0 | 0.00629 | B:GLU57;B:THR770;B:GLN774;B:GLN807;B:ASN808;B:SER1106;B:LYS1107;B:GLU1108;B:SER1136;B:THR1138;B:LYS1200;B:GLU1219;B:GLN1221;B:HIS1311;B:THR1314;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:THR1330;B:ARG1333;B:ARG1335 | 24 |
3be76140-eb48-57f6-81b8-06507b583158 | mythos_preview_multi_target_cas9_rank09 | Mythos Preview | multi_target | Cas9 | 9 | 80 | DIVDFLINTVKEILSLPPVLMRDEVRATLRSVELLYKRYPNNPAVRLALQKLREAVQEPDIGRREKILTDLLNELEKLKK | PXDesign | Caliby (SolubleCaliby) | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.06 | 39.3332 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank09/insilico/ | 0 | 0.00604 | 0 | 0.04118 | 0.617917 | 0.68322 | 0 | 0.0888 | null | null | 0 | 0.00444 | 0 | 0.02625 | 0 | 0.00508 | 0 | 0.0066 | 0 | 0.00548 | B:GLU57;B:ALA61;B:THR770;B:GLN774;B:THR804;B:GLN807;B:ASN808;B:SER1106;B:LYS1107;B:GLU1108;B:SER1136;B:PRO1137;B:THR1138;B:LYS1200;B:TYR1201;B:ALA1215;B:GLU1219;B:GLN1221;B:HIS1311;B:THR1314;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:THR1330;B:ARG1333;B:ARG1335 | 29 |
4c602b46-fd8f-5844-b1a9-94b3b263ba26 | mythos_preview_multi_target_cas9_rank10 | Mythos Preview | multi_target | Cas9 | 10 | 80 | MAEIENRLKDLAKEYNVSVETMRKIVKALMDYEIENDPLFAEEVKGLSEEDKLGLTLDYFKQLSPETRDSLLKMAAEILA | PXDesign | SolubleMPNN | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 2.35 | 100 | binder | 400 | 6,000 | 0.00198 | not_tested | null | not_tested | null | not_tested | null | not_tested | null | binder | 400 | false | null | twist_only_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank10/insilico/ | 0 | 0.00596 | 0 | 0.02619 | 0.469698 | 0.49631 | 0 | 0.36179 | null | null | 0 | 0.01548 | 0 | 0.00885 | 0.016677 | 0.00597 | 0 | 0.00734 | 0.011669 | 0.00595 | B:ASP54;B:GLU60;B:ALA61;B:LEU64;B:ASN767;B:THR769;B:SER777;B:GLU779;B:THR804;B:GLN807;B:ARG976;B:GLU977;B:LYS1107;B:GLU1108;B:SER1109;B:LEU1111;B:ARG1114;B:SER1136;B:LYS1200;B:TYR1201;B:GLN1221;B:THR1314;B:ALA1320;B:ALA1322;B:ASP1332;B:ARG1333;B:ARG1335 | 27 |
c48af7b4-a8e9-52bc-a293-7cd80242ee97 | mythos_preview_multi_target_cas9_rank11 | Mythos Preview | multi_target | Cas9 | 11 | 80 | DIVDFLVETVKEILSLPPTLMRDAVRATLRSVKLLEKRYPNNEAVRLAVQKLEEAVSTPDIGERERILQDLLKELEKLKK | PXDesign | Caliby (SolubleCaliby) | 4 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.12 | 33.0706 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank11/insilico/ | 0 | 0.00508 | 0 | 0.04153 | 0 | 0.03137 | 0 | 0.14145 | null | null | 0 | 0.00821 | 0 | 0.12545 | 0 | 0.00566 | 0 | 0.00616 | 0 | 0.00636 | B:GLU57;B:ALA61;B:GLN774;B:GLN807;B:SER1106;B:LYS1107;B:GLU1108;B:SER1136;B:THR1138;B:LYS1200;B:TYR1201;B:ALA1215;B:GLU1219;B:GLN1221;B:HIS1311;B:THR1314;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:THR1330;B:ARG1333;B:ARG1335 | 25 |
1e1c863b-966f-58e9-a601-bdb4c46ccb2b | mythos_preview_multi_target_cas9_rank12 | Mythos Preview | multi_target | Cas9 | 12 | 80 | TAEVELRLKKLADEFNISEEEMRKIVQTLMDYEEKNDPEFAKEVEGLSEVDRLGVTLDYLDELSPEVRKIVLEMARELLS | PXDesign | SolubleMPNN | 5 | ordered_sequence_backbone | medium | binder | 559.517254 | 3,545.897461 | 0.001967 | false | 2 | 1.6 | 98.6455 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | true | 676.795754 | adaptyv_only_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank12/insilico/ | 0 | 0.00631 | 0.267195 | 0.52543 | 0.60856 | 0.64326 | 0 | 0.37665 | null | null | 0 | 0.00882 | 0 | 0.10164 | 0 | 0.00606 | 0 | 0.41019 | 0 | 0.00642 | B:ASP54;B:GLU60;B:ALA61;B:LEU64;B:LYS65;B:ASN767;B:THR769;B:SER777;B:GLU779;B:THR804;B:GLN807;B:ARG976;B:GLU977;B:LYS1107;B:GLU1108;B:SER1109;B:LEU1111;B:ARG1114;B:ASP1135;B:SER1136;B:TYR1201;B:GLN1221;B:THR1314;B:ALA1320;B:ALA1322;B:ALA1323;B:ASP1332;B:ARG1333;B:ARG1335;B:THR1337 | 30 |
884b2c06-ebdd-517b-bb7d-1306528eba54 | mythos_preview_multi_target_cas9_rank13 | Mythos Preview | multi_target | Cas9 | 13 | 72 | SEKDKEEFLKELEKIDKLPIDEVEAEAKDLYAKYKDKFTTKEIVDIIENSKLDKRVKELILKAIKDYEVKYG | BoltzGen | SolubleMPNN | 6 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.35 | 99.5224 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank13/insilico/ | 0 | 0.55346 | 0 | 0.55057 | 0.447476 | 0.6709 | 0.391504 | 0.53742 | null | null | 0 | 0.01041 | 0.17081 | 0.59387 | 0 | 0.03604 | 0.242047 | 0.53885 | 0 | 0.00606 | B:ASN14;B:GLN774;B:GLU779;B:THR804;B:GLN807;B:ARG976;B:SER1106;B:LYS1107;B:GLU1108;B:SER1109;B:SER1136;B:PRO1137;B:THR1138;B:SER1216;B:GLU1219;B:ALA1320;B:PRO1321;B:ALA1323;B:ARG1333;B:ARG1335 | 20 |
9c5225d9-4eca-55a7-95e0-cae8a6584158 | mythos_preview_multi_target_cas9_rank14 | Mythos Preview | multi_target | Cas9 | 14 | 72 | SEEDKEKFLKELEEIDKLPLDEVEVEAKELYAKYKDKFSEAEIIEIIENSKLDEEVKRRILKAIRDYNDEYS | BoltzGen | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.62 | 98.3526 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank14/insilico/ | 0.010135 | 0.49229 | 0.121967 | 0.43944 | 0.475711 | 0.64499 | 0.463776 | 0.5472 | null | null | 0 | 0.01695 | 0 | 0.50232 | 0 | 0.00542 | 0 | 0.04151 | 0 | 0.00773 | B:THR13;B:ASN14;B:SER55;B:LYS65;B:LEU727;B:ALA728;B:GLY729;B:ILE733;B:LYS734;B:ILE737;B:ASN767;B:GLN771;B:GLN774;B:LYS775;B:ILE927;B:ARG976;B:SER1106;B:LYS1107;B:GLU1108;B:SER1109;B:SER1136;B:THR1138;B:GLU1219;B:ALA1320;B:PRO1321;B:ARG1333;B:ARG1335 | 27 |
71b146a8-2850-5906-a939-108c6b0a32df | mythos_preview_multi_target_cas9_rank15 | Mythos Preview | multi_target | Cas9 | 15 | 71 | MLVERGNILAGNGHLENAALLYESAGELGEELGGDPKKVAELYRKAAELYDLAGDKEKAEELYKKAEELLK | Proteina-Complexa | SolubleMPNN | 0 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.29 | 96.2467 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank15/insilico/ | 0 | 0.06272 | 0 | 0.52793 | 0.535718 | 0.48747 | 0.230592 | 0.71482 | null | null | 0 | 0.00666 | 0 | 0.01338 | 0 | 0.00691 | 0 | 0.01071 | 0 | 0.00673 | A:ASN14;A:SER15;A:LEU52;A:ASP54;A:GLU57;A:ALA61;A:LEU64;A:GLY366;A:SER368;A:GLU371;A:THR769;A:THR770;A:GLN771;A:GLN774;A:GLN807;A:ARG976;A:GLU977;A:ASN980;A:HIS982;A:HIS983;A:LYS1096;A:LYS1107;A:GLU1108;A:SER1136;A:PRO1137;A:THR1138;A:LYS1200;A:MET1213;A:ALA1215;A:SER1216;A:GLU1219;A:GLN1221;A:LYS1222;A:GLU1307;A:ILE13... | 49 |
48747df3-bf2a-57ee-8986-0bffd7472b46 | mythos_preview_multi_target_cas9_rank16 | Mythos Preview | multi_target | Cas9 | 16 | 72 | SEEEKEKLLEELKEIDKLPLDQVEAEAKDLYRKYRDKFTIEEIRKLIEESKLDARVKELILRAIDEVEIEEG | BoltzGen | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.59 | 100 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank16/insilico/ | 0.011992 | 0.00628 | 0 | 0.00569 | 0.4032 | 0.58931 | 0.418297 | 0.67051 | null | null | 0 | 0.00557 | 0 | 0.48192 | 0 | 0.00581 | 0 | 0.06441 | 0 | 0.00586 | B:THR13;B:ASN14;B:ASN767;B:GLN771;B:GLN774;B:LYS775;B:ARG778;B:ARG976;B:SER1106;B:LYS1107;B:GLU1108;B:SER1109;B:SER1136;B:PRO1137;B:THR1138;B:SER1216;B:GLU1219;B:ALA1320;B:PRO1321;B:ALA1323;B:ARG1333;B:ARG1335 | 22 |
32e53d43-4f4e-5711-bff9-1990ca63168b | mythos_preview_multi_target_cas9_rank17 | Mythos Preview | multi_target | Cas9 | 17 | 72 | SEKDKEEFLKKLEEIDKLPLDEVATAAKELYAEYKDKFSTAEIVEIIENSKLDKRVKELILKAIKDWEDLNS | BoltzGen | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.44 | 100 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank17/insilico/ | 0 | 0.42623 | 0 | 0.00568 | 0.386397 | 0.61353 | 0.300613 | 0.58101 | null | null | 0 | 0.0117 | 0 | 0.04103 | 0 | 0.00574 | 0 | 0.007 | 0 | 0.00598 | B:THR13;B:ASN14;B:SER55;B:LYS65;B:LEU727;B:ALA728;B:GLY729;B:ILE733;B:LYS734;B:ILE737;B:ASN767;B:GLN771;B:GLN774;B:LYS775;B:ILE927;B:ARG976;B:SER1106;B:LYS1107;B:GLU1108;B:SER1109;B:SER1136;B:THR1138;B:GLU1219;B:ALA1320;B:PRO1321;B:ARG1333;B:ARG1335 | 27 |
45e12543-ce7d-5e8c-922e-dbe57ccfebd4 | mythos_preview_multi_target_cas9_rank18 | Mythos Preview | multi_target | Cas9 | 18 | 72 | SEEEKKKLLEELEEIDKLPLDQVEAEAKDLYLKYKDKFTPEEIKELIKNSKLDAEVKRLILKAIDEVLERES | BoltzGen | SolubleMPNN | 3 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.87 | 100 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank18/insilico/ | 0 | 0.46278 | 0.011708 | 0.00559 | 0.360574 | 0.65132 | 0.438831 | 0.54876 | null | null | 0 | 0.01025 | 0 | 0.57074 | 0 | 0.00509 | 0 | 0.00616 | 0.231112 | 0.00343 | B:LEU64;B:GLN774;B:SER777;B:ARG778;B:GLN807;B:ARG976;B:SER1106;B:LYS1107;B:GLU1108;B:SER1109;B:SER1136;B:THR1138;B:SER1216;B:GLU1219;B:ALA1320;B:PRO1321;B:ALA1323;B:ARG1333;B:ARG1335 | 19 |
906ce7d0-d615-5089-abcb-c1bff6962f5a | mythos_preview_multi_target_cas9_rank19 | Mythos Preview | multi_target | Cas9 | 19 | 72 | SEEDKKKLLEELEEIDKLPLSEVEAEAKDLYLKYKDKFTTDEIKEIIRESKLDKRVKELILKAIKEVEEREG | BoltzGen | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.27 | 99.5533 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank19/insilico/ | 0.011464 | 0.65891 | 0 | 0.17469 | 0.224668 | 0.53292 | 0.382682 | 0.67126 | null | null | 0 | 0.02097 | 0 | 0.09765 | 0 | 0.00571 | 0.199974 | 0.61355 | 0 | 0.00532 | B:THR13;B:ASN14;B:THR270;B:ASN767;B:GLN771;B:GLN774;B:LYS775;B:ARG778;B:ARG976;B:SER1106;B:LYS1107;B:GLU1108;B:SER1109;B:SER1136;B:THR1138;B:SER1216;B:GLU1219;B:ALA1320;B:PRO1321;B:ALA1323;B:ARG1333;B:ARG1335 | 22 |
7da2463b-c018-5ed0-b96f-87bd97197f54 | mythos_preview_multi_target_cas9_rank20 | Mythos Preview | multi_target | Cas9 | 20 | 77 | SKEELFKKIVEELKKTKDEKERIELVRKFLRELLDMDSAELEALSDEQLLALADLLLKLYEEGKSLKEIEEEVKKFL | Genie3 | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.34 | 91.0611 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank20/insilico/ | 0 | 0.0312 | 0 | 0.00466 | 0.504356 | 0.90537 | 0 | 0.03911 | null | null | 0 | 0.00356 | 0 | 0.0944 | 0 | 0.0036 | 0 | 0.00384 | 0 | 0.01945 | B:LYS1107;B:ARG1114;B:SER1116;B:LYS1118;B:ASP1135;B:SER1136;B:ASP1332;B:ARG1333;B:ARG1335;B:THR1337 | 10 |
101ede8c-09c8-5b40-8a1e-aa8695517324 | mythos_preview_multi_target_cas9_rank21 | Mythos Preview | multi_target | Cas9 | 21 | 80 | MKLSKGEIAASIYELAVNLYTKNVPKEEMIKIVLEEAEEFMKETGYSREEMVEILRHLAEIEPDKEVAEVLREVARKLEG | PXDesign | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.58 | 96.4087 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank21/insilico/ | 0 | 0.00951 | 0 | 0.02381 | 0 | 0.03219 | 0 | 0.01064 | null | null | 0.010742 | 0.02773 | 0 | 0.00993 | 0.27879 | 0.38636 | 0.166779 | 0.34468 | 0.245519 | 0.51942 | B:GLU584;B:ASP585;B:MET694;B:MET763;B:ARG765;B:ASN767;B:GLN768;B:THR769;B:GLY773;B:GLN774;B:LYS775;B:ASN776;B:SER777;B:ARG778;B:VAL922;B:ARG925;B:LYS929;B:ALA932;B:LYS959;B:TYR1010;B:GLY1011;B:GLY1030;B:ALA1032;B:THR1033;B:TYR1036;B:PHE1037 | 26 |
338f2fbb-4c48-564b-a180-0e2be4e20b7e | mythos_preview_multi_target_cas9_rank22 | Mythos Preview | multi_target | Cas9 | 22 | 80 | MKLSKGEIAATIYEEAVRLYEKNVPKEEMVKIVLELAEEFMKEEGYSKEEMVEILRHLAEREEDPEVREVLLEVARKLEG | PXDesign | SolubleMPNN | 1 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 0.63 | 98.0181 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank22/insilico/ | 0 | 0.02513 | 0 | 0.014 | 0.017399 | 0.35011 | 0 | 0.01005 | null | null | 0.056391 | 0.04491 | 0.013561 | 0.23711 | 0.285659 | 0.42886 | 0.032682 | 0.48722 | 0.14679 | 0.32603 | B:GLU584;B:ASP585;B:GLU910;B:LEU911;B:ALA914;B:LYS918;B:ARG919;B:VAL922;B:THR924;B:GLN926;B:LYS929;B:LYS959;B:TYR1010;B:GLY1011;B:GLY1030;B:ALA1032;B:THR1033;B:LYS1035;B:TYR1036;B:PHE1037 | 20 |
01d21bdf-3816-5c4a-946b-f7209b662fad | mythos_preview_multi_target_cas9_rank23 | Mythos Preview | multi_target | Cas9 | 23 | 72 | SEEDKEEFLKELEKIDKLPLDEVETEAKELYAKYRDKFTTAEIIELIENSKLDEEVKRRILKAIRDWEDKYS | BoltzGen | SolubleMPNN | 5 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.8 | 100 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank23/insilico/ | 0.011939 | 0.5305 | 0 | 0.00598 | 0.41177 | 0.66912 | 0 | 0.07665 | null | null | 0 | 0.01067 | 0 | 0.5421 | 0 | 0.00516 | 0 | 0.03373 | 0 | 0.00637 | B:THR13;B:ASN14;B:SER55;B:LYS65;B:LEU727;B:ALA728;B:GLY729;B:ILE733;B:LYS734;B:ILE737;B:ASN767;B:GLN771;B:GLN774;B:LYS775;B:ILE927;B:ARG976;B:SER1106;B:LYS1107;B:GLU1108;B:SER1109;B:SER1136;B:THR1138;B:GLU1219;B:ALA1320;B:PRO1321;B:ARG1333;B:ARG1335 | 27 |
12722273-8fea-5f5d-96f3-d5d004d4a55e | mythos_preview_multi_target_cas9_rank24 | Mythos Preview | multi_target | Cas9 | 24 | 72 | SKEEKEELKKELEKLGSLPLEVIEAEAKDLWAKYKDKFTKEEIIKIIDESDLDETVKRLIKRAIDAVASETD | BoltzGen | SolubleMPNN | 2 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 2 | 1.42 | 100 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank24/insilico/ | 0 | 0.14162 | 0 | 0.09427 | 0.378595 | 0.38731 | 0.312354 | 0.55638 | null | null | 0 | 0.00625 | 0 | 0.0672 | 0 | 0.03032 | 0 | 0.39866 | 0 | 0.00589 | B:THR13;B:ASN14;B:SER55;B:GLU57;B:LYS65;B:ALA764;B:ARG765;B:GLU766;B:ASN767;B:GLN768;B:THR769;B:GLN771;B:GLN774;B:ARG778;B:LYS974;B:ARG976;B:SER1106;B:LYS1107;B:GLU1108;B:SER1109;B:SER1216;B:GLU1219;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:ARG1333;B:ARG1335 | 28 |
563021b5-d509-519e-9b4f-ca2df716f246 | mythos_preview_multi_target_cas9_rank25 | Mythos Preview | multi_target | Cas9 | 25 | 90 | AEKVYVLKPDVDTVVDAVEDAIKQGATRIIIHNADEALGTDEVMRGVLELAKKNNVKVVVETTSKILAERIVKLAEELGVEDLVEVKLHM | BoltzGen | SolubleMPNN | 1 | ordered_sequence_backbone | medium | non_binder | null | null | null | null | 3 | 1.73 | 100 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | neither_bind | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank25/insilico/ | 0 | 0.00731 | 0 | 0.00665 | 0.247324 | 0.59521 | 0 | 0.59861 | null | null | 0 | 0.01684 | 0 | 0.53682 | 0 | 0.03716 | 0 | 0.61265 | 0 | 0.00644 | B:GLY12;B:THR13;B:ASN14;B:GLU57;B:GLU60;B:ALA61;B:LEU64;B:ARG71;B:GLU370;B:ALA764;B:ARG765;B:GLU766;B:ASN767;B:GLN768;B:THR769;B:THR770;B:GLN771;B:GLN774;B:LYS775;B:GLN807;B:ARG976;B:GLU977;B:LYS1107;B:GLU1108;B:SER1109;B:ALA1320;B:PRO1321;B:ALA1322;B:ALA1323;B:PHE1324;B:LYS1325;B:ARG1333;B:ARG1335 | 33 |
667ccc06-b539-5089-ab33-ee22f8558c68 | mythos_preview_multi_target_cas9_rank26 | Mythos Preview | multi_target | Cas9 | 26 | 80 | MAEIRNRLRDLAEEYGMSVKQMEEIVRALMEMLEEIDPEFAEEVKGLSEDERLALTLEYLRQLSPTTRESLLKLAAERVA | PXDesign | SolubleMPNN | 0 | ordered_sequence_backbone | null | not_tested | null | null | null | null | null | 0.57 | 98.9262 | non_binder | null | null | null | not_tested | null | not_tested | null | not_tested | null | not_tested | null | non_binder | null | false | null | twist_only_tested | not_tested | null | not_tested | null | designs/Cas9/mythos_preview_multi_target_cas9_rank26/insilico/ | 0 | 0.00627 | 0 | 0.6371 | 0.085654 | 0.50675 | 0.019393 | 0.00751 | null | null | 0 | 0.00637 | 0 | 0.04168 | 0 | 0.0068 | 0 | 0.00707 | 0 | 0.00625 | A:THR13;A:ASN14;A:LEU52;A:ASP54;A:SER55;A:GLY56;A:GLU57;A:THR58;A:GLU60;A:ALA61;A:LEU64;A:GLU722;A:SER730;A:ALA732;A:ARG765;A:GLU766;A:ASN767;A:THR769;A:GLY773;A:GLN774;A:LYS775;A:ASN776;A:SER777;A:GLN807;A:ARG976;A:GLU977;A:ILE978;A:ASN979;A:ASN980;A:HIS982;A:HIS983;A:LYS1096;A:LYS1107;A:SER1109;A:LYS1200;A:TYR1201;A:... | 53 |
End of preview. Expand in Data Studio
Claude protein binder design — data release v1.0
1,440 de novo miniprotein binders (50 to 120 residues) against 16 targets, designed by two Claude models operating as autonomous protein-design agents (Mythos Preview, 900 designs; Opus 4.8, 540 designs) and characterized at two contract research organizations, Adaptyv Bio (cell-free expression; SPR/BLI kinetics with the design immobilized) and Twist Bioscience (Fc-fusion expression; capture SPR with a six-point antigen titration). The release links, per design: binding calls and kinetics from both vendors with raw sensorgrams and report images, a per-design comparison and final assessment of the two, the design model, seed-best co-folded predictions from ten structure predictors with per-seed scores, and step-level design provenance.
Nine experimentally confirmed de novo binders from this release, shown first as design models bound to their targets (grey) and then on their own, arranged to spell ANTHROPIC. Each letter is a real structure from data/designs/…/insilico/ drawn as a cartoon, rotated and uniformly scaled only (no deformation); the BHRF1 “C” has no design-time complex in the release and is shown as its co-folded prediction. A = mythos_preview_single_target_nipahg_rank15, N = opus_4_8_multi_target_trem2_rank11, T = mythos_preview_single_target_trka_rank06, H = mythos_preview_single_target_il7ra_rank20, R = mythos_preview_single_target_il7ra_rank19, O = mythos_preview_single_target_egfr_rank24, P = mythos_preview_multi_target_vegfa_rank26, I = mythos_preview_single_target_trem2_rank02, C = opus_4_8_multi_target_bhrf1_rank01. KD values in the captions are the pooled values in design_summary.
Dataset viewer: the default subset is
design_summary(one row per design, 1,440 rows). Every Parquet table indata/tables/is exposed as its own subset (e.g.wetlab_summary,adaptyv_replicates,twist_fits,insilico_cofold_predictions); pick it from the Subset menu or load it withload_dataset("Anthropic/claude-protein-binder-design", "<subset>", split="full"). Per-design folders underdata/designs/(structures, sensorgram PNGs, per-curve CSVs) are files to browse/download, not viewer tables.
Targets: 15-PGDH, BBF-14, BHRF1, SpCas9, EGFR, IL-7Rα, latent GDF-8 (pro-myostatin), mature GDF-8, MBP, Nipah virus G, PD-L1, RBX1, TNF-α, TREM2, TrkA, VEGF-A. Wet-lab measurements of the 120 mature GDF-8 designs were inconclusive (the antigen aggregated and bound assay surfaces non-specifically) and are not included; those designs ship with design models, co-folds and provenance only. Across the other 15 targets, 354 of 1,320 designs are binders by the release's two-vendor assessment.
Repository layout
README.md this card
data/ the data release, unpacked (129,003 files, 9.9 GB)
README.md start here: layout, the two assays in brief, headline numbers
docs/ DATA_NOTES.md, WETLAB.md, INSILICO.md, PROVENANCE.md, LOOKUP_TABLES.md, scripts/
tables/ 20 Parquet tables (design summary, wet-lab summary and measurements,
Adaptyv Bio results/replicates/reads/fits, Twist Bioscience fits/titer/raw segments,
antigens and controls, co-fold predictions, epitope contacts, provenance,
target constructs, column dictionary)
manifests/ file-level manifests for structures, sensorgram images and raw traces
designs/<target>/<design>/ per design: design model, seed-best co-fold per predictor, Adaptyv Bio raw reads,
fit curves and sensorgram images, Twist Bioscience raw traces and report images
controls/ assay controls and reference binders measured alongside the designs
MANIFEST.sha256, LICENSE.md, CITATION.cff
protein_binder_design_data_release_docs_tables.zip
README, docs/, tables/ and manifests/ only (33 MB), for a quick start without
the per-design files
structure_and_pae/ companion structure tier
README.md layout and column definitions of the structure tier
predictions.parquet one row per predicted model (113,550): predictor, seed, stoichiometry, scores, paths
design_names.csv, design_models.csv, MANIFEST.sha256, LICENSE.md, CITATION.cff
protein_binder_design_structure_and_pae_release.zip
74.5 GB: for every design, the design model and every seed of every co-fold
(ten predictors, five seeds each) as mmCIF with the full PAE matrix (pae.npz)
prompts/ the campaign prompts
README.md how the prompt, kickoff message and resource corpus fit together
prompts/ multi-target campaign prompt, 17 single-target prompts, kickoff messages, figures
REDISTRIBUTION_NOTES.csv provenance and licence class of every corpus source
protein_binder_design_prompts_release.zip
1.16 GB: the prompts plus the external resource corpus they reference
(cited web pages, ProteinBase collections, method and model papers)
The complete data release is also what data/ was unpacked from; its archive form (protein_binder_design_data_release.zip, 5.65 GB, 129,003 files with MANIFEST.sha256) can be rebuilt by zipping data/, and python data/docs/scripts/verify_manifest.py re-hashes every file against the manifest.
SHA-256 of the archives in this repository:
bb7d45f9957bee70e715191566577d59e69363e42f18981aa96468b4b6547dec protein_binder_design_data_release_docs_tables.zip
2b39a3c07cda2823eedc66886aeeeb1d79c7a6788e2b8e979827262ed40ce359 structure_and_pae/protein_binder_design_structure_and_pae_release.zip
ce86bae3d22922f3b1a06235688be79ccc209fcb1a61066d32471d256eb017c5 prompts/protein_binder_design_prompts_release.zip
Getting started
from huggingface_hub import hf_hub_download
import pandas as pd
repo = "Anthropic/claude-protein-binder-design"
designs = pd.read_parquet(hf_hub_download(repo, "data/tables/design_summary.parquet", repo_type="dataset")) # one row per design (1,440)
wetlab = pd.read_parquet(hf_hub_download(repo, "data/tables/wetlab/summary.parquet", repo_type="dataset")) # two-vendor comparison and final call
print(designs[["full_name", "target", "design_model", "binder_final", "kd_nM_final"]].head())
# tables and documentation only
hf download Anthropic/claude-protein-binder-design --repo-type dataset --include "data/tables/*" "data/docs/*" "data/README.md"
# one design's folder
hf download Anthropic/claude-protein-binder-design --repo-type dataset --include "data/designs/EGFR/mythos_preview_single_target_egfr_rank02/*"
Every table joins on uuid; full_name (<model>_<campaign>_<target>_rank<NN>) names the per-design folder. data/tables/column_dictionary.parquet defines every column of every table; data/docs/DATA_NOTES.md lists the caveats that matter when interpreting the measurements.
License and citation
Data and documentation: CC BY 4.0. Scripts included in the archives: MIT. Third-party material (structure-prediction outputs, reference sequences, vendor report images, reagent names) keeps its own terms; see LICENSE.md in each archive. Please cite as given in CITATION.cff.
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