Dataset Viewer
Auto-converted to Parquet Duplicate
text
stringlengths
220
2.92k
label
class label
23 classes
Effects of milk, prostaglandin, and antacid on experimentally induced duodenitis in the rat. Use of myeloperoxidase as an index of inflammation. Ulcerogenesis of the duodenal mucosa frequently involves an inflammatory reaction with infiltration of leukocytes. Measurement of neutrophil myeloperoxidase activity might t...
5C06
Maternal mortality in the United States, 1979-1986. To understand better the epidemiology and to describe the causes of maternal death, we reviewed all identified maternal deaths in the United States and Puerto Rico for 1979-1986. The overall maternal mortality ratio for the period was 9.1 deaths per 100,000 live bir...
12C13
Hemopump ventricular support for patients undergoing high risk coronary angioplasty. Prophylactic implantation of a Hemopump (Johnson and Johnson, Skillman, NJ) has been evaluated in nine patients selected for high risk coronary angioplasty. They were unstable patients, refractory to maximal pharmacology, with indica...
13C14
Spontaneous rheumatoid-like arthritis in a line of mice sensitive to collagen-induced arthritis. Twenty-eight percent of 13-month-old male mice of the high antibody responder line of Biozzi's selection I (HI) spontaneously developed a long-lasting inflammatory arthritis. This disease was clinically and histologically...
16C17
Intraoperative echocardiography in infants and children with congenital cardiac shunt lesions: transesophageal versus epicardial echocardiography. To determine the utility and limitations of intraoperative transesophageal echocardiography in infants and children with congenital intracardiac shunts, intraoperative tran...
15C16
Increased birth prevalence of cardiac defects in Yuma, Arizona A systematic study was undertaken to estimate the birth prevalence of congenital heart disease because there was a clinical impression that a disproportionate number of cases occurred in Yuma, Arizona. Control data were obtained from Sierra Vista, Arizon...
15C16
Experimental studies of the physiologic properties of technetium-99m isonitriles. Recently, efforts have been directed at the development of technetium-99m (Tc-99m)-labeled isonitrile compounds for assessment of regional perfusion and viability after experimental myocardial infarction or ischemia. One of the most pro...
13C14
Penetrating injuries of the abdominal aorta. The charts of 56 consecutive patients with penetrating injuries to the abdominal aorta were reviewed in an attempt to identify prognostic factors. Mechanism of injury was gunshot wound (GSW), 82 per cent (.22 cal: 15.2%; greater than .38 cal: 84.8%); shotgun wound (SGW), 5...
20C21
Submersion in The Netherlands: prognostic indicators and results of resuscitation. STUDY OBJECTIVES: To analyze prognostic indicators and the outcome of resuscitation in submersion victims (drowning and near drowning). DESIGN: Retrospective study. SETTING: Intensive and Respiratory Care Unit. Between January 1, 197...
20C21
Estimation of the amount of alcohol ingested from a single blood alcohol concentration. Capillary blood alcohol concentrations (BAL) measured in 22 young adult male volunteers each of whom received three different treatments of alcohol (total N = 66) have been related quantitatively to the dose of alcohol ingested. L...
20C21
Predictive value of lipoprotein (a) and other serum lipoproteins in the angiographic diagnosis of coronary artery disease. To determine the relation among lipids in predicting coronary artery disease (CAD), 213 patients undergoing diagnostic angiography for suspected CAD were prospectively studied. Twenty-one patient...
13C14
Alcohol and trauma. An endemic syndrome. Injuries are a pervasive and costly problem, and alcohol use appears to be an important risk factor for injury. We examined the blood alcohol levels and selected demographic and epidemiologic variables recorded on trauma patients by 1 trauma center for a 28-month period. A to...
20C21
Percutaneous central venous catheterization. Three years' experience in a neonatal intensive care unit. Prolonged venous access is desirable in very-low-birth-weight infants and infants for whom feedings are contraindicated. We prospectively evaluated 481 small-diameter venous catheters placed percutaneously in 317 p...
0C01
Alternating cisplatinum and VAC ineffective in end stage squamous cell carcinoma of the head and neck. Sixteen patients with end stage squamous cell carcinoma of the head and neck were admitted to a phase II study of alternating courses of cisplatinum (100 mg/m2) and VAC (vincristine 1.4 mg/m2, adriamycin 50 mg/m2, cy...
3C04
Bioaerosols: prevalence and health effects in the indoor environment. Assessing the role of bioaerosols in residence-related symptoms involves (1) determining that symptoms are related to the residence by medical examination and careful questioning, (2) connecting reported symptoms with known or hypothesized effects o...
0C01
Digital rectal examination in the early detection of prostate cancer. Screening using digital rectal examination improves the clinical stage distribution of prostate cancer and prolongs survival. Unfortunately, digital rectal examination may not be sensitive enough to detect the small-volume tumors that are most amen...
11C12
Hemorrhage in mice produces alterations in pulmonary B cell repertoires. Nosocomial pneumonia occurs frequently after hemorrhage and trauma and contributes to the increased incidence of morbidity and mortality after severe injury. The production of secretory antibodies by mucosally associated B cells is an important ...
22C23
Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group. There is a varying hormonal activation in heart failure. To be able to evaluate this activation and relate it to prognosis, we took blood samples at baseline and a...
13C14
Transrectal sonographic cystourethrography: studies in stress urinary incontinence. Transrectal ultrasonic sagittal transducer is an excellent modality to image the bladder and urethra in dynamic change. In female patients, we found it is also helpful for the diagnosis of urinary stress incontinence. The posterior u...
11C12
Right ventricular growth after transventricular pulmonary valvotomy and central aortopulmonary shunt for pulmonary atresia and intact ventricular septum. We performed transventricular pulmonary valvotomy as initial surgery in 22 consecutive patients with pulmonary atresia and intact ventricular septum who had a patent...
15C16
Hemodynamic efficacy of rapid saline infusion and dobutamine versus saline infusion alone in a model of cardiac rupture. Despite recent reports describing survival after cardiac rupture, the effectiveness of circulatory support while awaiting definitive surgical treatment is controversial. To assess the efficacy of v...
13C14
Adult minimal change glomerulopathy with acute renal failure. Oliguric acute renal failure occurs in some adult patients with minimal change glomerulopathy. To look for clinical and pathologic factors that increase the risk for developing acute renal failure, 21 adults with minimal change glomerulopathy and a serum c...
11C12
Mechanisms of edema formation in experimental autoimmune encephalomyelitis. The contribution of inflammatory cells. Most of the central nervous system (CNS) endothelium regulates the passage of solutes and functions as a blood-brain barrier (BBB). During experimental autoimmune encephalomyelitis (EAE), an inflammator...
22C23
Rhabdomyosarcomas in the head and neck: MR imaging evaluation. To determine the typical magnetic resonance (MR) signal intensity characteristics of rhabdomyosarcomas, short repetition time (TR)/short echo time (TE) (T1-weighted) and long TR (proton density and T2-weighted) images of 13 patients with rhabdomyosarcomas ...
3C04
Agreement between two dietary methods in the measurement of alcohol consumption. This study compares estimates of alcohol consumption from two dietary methods: a self-reported diet diary and a quantitative food frequency questionnaire. In the 1984-85 University of Michigan Food Frequency Study, 228 black and white, m...
20C21
Abnormal vitamin B6 status in childhood leukemia. Vitamin B6 is involved in many biological processes of potential relevance to carcinogenesis and tumor growth, including DNA synthesis and maintenance of immunocompetence, yet very little information exists on B6 nutritional status in childhood leukemia. Using a radio...
3C04
Studies of salt intake in hypertension. What can epidemiology teach us? It has been suggested that small changes in population blood pressure will have a major impact upon the incidence of cardiovascular disease caused by blood pressure elevation. Early reports indicated a close correlation between intercultural diff...
13C14
Digitalis-like activity in human plasma: relation to blood pressure and sodium balance. PURPOSE: On the assumption that renal tubular cells are more important as the target cells for a natriuretic factor than blood cells, we used a well-characterized cultured renal tubular cell line, Madin-Darby canine kidney (MDCK), ...
13C14
Chromosomal region of the cystic fibrosis gene in yeast artificial chromosomes: a model for human genome mapping. A general strategy for cloning and mapping large regions of human DNA with yeast artificial chromosomes (YAC's) is described. It relies on the use of the polymerase chain reaction to detect DNA landmarks ...
15C16
Serum estradiol as an aid in the diagnosis of ectopic pregnancy. The value of serum beta-hCG measurement in the diagnosis of ectopic pregnancy is well established, and there have been recent studies on the use of serum progesterone levels. However, we have been unable to find any reports on the potential application ...
12C13
Mortality from pulmonary embolism in the United States: 1962 to 1984. To examine the effect of advances in the prevention of and therapy for PE, we reviewed mortality for PE in the United States from 1962 to 1984. Age-adjusted PE mortality increased by 67 to 100 percent between 1962 and 1974 for white and non-white m...
7C08
Cytopathology of adenovirus keratitis by replica technique. Corneal replicas were made from the severely affected eyes of 12 patients presenting with typical signs and symptoms of epidemic keratoconjunctivitis. Adenovirus was isolated from the eyes. Histopathological study of the replicas and cytology of diseased ce...
10C11
Radioimmunoscintigraphy using iodine-131-anti-CEA monoclonal antibodies and thallium-201 scintigraphy in medullary thyroid carcinoma: a case report. This case report demonstrates the use of thallium-201 (201Tl) scans versus iodine-131- (131l) anti-CEA F(ab')2 scans in a patient with high serum CEA levels due to metast...
3C04
Effect of procaterol on arterial blood gas in asthmatic children. We determined changes in arterial blood gas after the inhalation of procaterol, a highly beta 2-selective and long-acting adrenergic agonist, in 11 asthmatic children. Seven of the patients, with a maximum fall of 14 mmHg (63.6%), showed a decrease in ...
19C20
Hodgkin's disease and CD30-positive anaplastic large cell lymphomas--a continuous spectrum of malignant disorders. A quantitative morphometric and immunohistologic study. The authors have examined cellular areas of lymphoma tissue in 28 cases of Hodgkin's disease (HD) or anaplastic large cell lymphoma (ALCL, 'Ki-1 cel...
19C20
Percutaneous transluminal coronary angioplasty of gastroepiploic artery graft. The right gastroepiploic artery is being used as a third arterial conduit for coronary artery bypass surgery. Presented here is a case demonstrating successful percutaneous transluminal coronary angioplasty of the gastroepiploic artery gra...
22C23
Mechanical disruption of pulmonary emboli in dogs with a flexible rotating-tip catheter (Kensey catheter). Pulmonary embolism was induced in 11 dogs by the injection of three- to four-day-old allogeneic blood clots. The clots were made radiopaque by soaking them in contrast material. The resulting clots were firm, 3...
7C08
An adherent subline of a unique small-cell lung cancer cell line downregulates antigens of the neural cell adhesion molecule. Small-cell lung cancer (SCLC) lines are distinguished from non-small-cell lung cancer (NSCLC) lines by their growth in floating aggregates, in contrast to the adherent monolayers formed by NSCL...
7C08
Spectrum of hemodynamic changes in cardiac tamponade. To investigate the pathophysiology of cardiac tamponade, the hemodynamics of 77 consecutive patients with greater than 150 ml of pericardial effusion were studied. Patients were classified into 3 groups based on the equilibration of intrapericardial with right atr...
13C14
Inferior vena caval filter thrombi: evaluation with intravascular US. A 20-MHz intravascular ultrasound (US) transducer inside a percutaneously inserted catheter was used to evaluate inferior vena caval (IVC) filters for thrombi in vitro and in vivo. Six different IVC filters were studied with intravascular US in a s...
13C14
Similar frequencies of renin gene restriction fragment length polymorphisms in hypertensive and normotensive subjects. A prospective study was conducted to compare the frequency of renin gene polymorphisms in normotensive and hypertensive subjects. Hypertensive (n = 102, blood pressure 168 +/- 17/103 +/- 9 mm Hg) and...
13C14
Effect of intravenous streptokinase on early mortality in patients with suspected acute myocardial infarction. A meta-analysis by anatomic location of infarction [published erratum appears in Ann Intern Med 1991 Mar 15;114(6):522] PURPOSE: To determine the effect of intravenous streptokinase on early mortality in pa...
13C14
Dynamic positron tomographic imaging with nitrogen-13 glutamate in patients with coronary artery disease: comparison with nitrogen-13 ammonia and fluorine-18 fluorodeoxyglucose imaging. This study was designed to test the usefulness of nitrogen-13 (N-13) glutamate imaging with positron emission tomography in defining ...
13C14
Regression of intracardiac thrombus after embolic stroke. Using two-dimensional echocardiography, we studied the pathophysiology of intracardiac thrombus regression accompanied by anticoagulant therapy in 82 consecutive patients with acute cardiogenic cerebral embolism. We noted intracardiac thrombus in 15 patients; ...
13C14
Reduction of mortality, sudden death and non-fatal reinfarction with beta-adrenergic blockers in survivors of acute myocardial infarction: a new hypothesis regarding the cardioprotective action of beta-adrenergic blockade. Beta-adrenergic blockers have been shown definitely to reduce the incidence of total mortality, ...
13C14
Modulation of interleukin-1 beta RNA in monocytic cells infected with human immunodeficiency virus-1. The effect of HIV-1 infection on cytokine levels was studied in monocytic cells by using Northern blotting analysis. Monoblasts (THP-1, U937) did not express IL-1 beta RNA even if the cells were infected with HIV-1. ...
19C20
Evolution of deep venous thrombosis: a prospective evaluation with US. Forty-six patients with a diagnosis of acute deep venous thrombosis (DVT) established by means of duplex ultrasound (US) were prospectively followed up with serial duplex US examinations during a 6-month period to assess the persistence of venous a...
13C14
A constitutive antibody in normal human serum directed against rabbit bone marrow cells: lack in parturients, neonates, and hematologic disorders. Normal human serum effectively inhibits a bioassay for erythropoietin based on DNA synthesis by rabbit erythroid precursors. This heat-sensitive inhibitory activity is rea...
14C15
Cup containment and orientation in cemented total hip arthroplasties. We reviewed the radiographs of 864 Charnley and STH (Zimmer) cemented total hip arthroplasties with a mean follow-up of seven years (maximum 16 years). Survivorship analysis was used to assess the correlation between radiographic performance and th...
22C23
Tension pneumopericardium as a complication of single-lung transplantation. Tension pneumopericardium is distinctly uncommon in the adult population. We present a case of tension pneumopericardium as a complication of lung transplantation in a 54-year-old woman with thromboembolic pulmonary hypertension who underwent...
13C14
Influence of postmortem time and temperature on osteoinductive activity of demineralized microperforated ethylene oxide-sterilized syngeneic bone implant in the rat. Bone morphogenetic protein is labile and easily inactivated by many extracorporeal factors. It is crucial to establish whether delay in retrieval of don...
22C23
The osteogenic response to distant skeletal injury. We tested the hypothesis that when one bone of the skeleton is injured, others experience an osteogenic response. Although similar or related phenomena have been observed previously, the purposes of the study were to determine if this response was reproducible, to c...
20C21
Soft tissue sarcomas of the head and neck in adults. We reviewed the clinical records and pathologic material of 176 adults with primary soft tissue sarcomas treated at Memorial Sloan-Kettering Cancer Center between 1950 and 1985. Seventy-two patients (41%) had low-grade sarcomas and 104 (59%) had high-grade sarcomas...
3C04
Effects of newborn screening of cystic fibrosis on reported maternal behaviour. Screening for cystic fibrosis is highly controversial. Concerns have been expressed that newborn screening may cause mothers, who had considered their child to be healthy before diagnosis, to overprotect their child. Some critics of scre...
15C16
Hair dryer burns in children. Three children with burn injuries caused by home hair dryers are described. In one patient the injury was believed to be accidental, and in the other two cases the injuries were deliberately caused by a caretaker. The lack of prior experience with hair dryer burns initially led to suspi...
20C21
Intraocular pressure changes and postural changes of intraocular pressure in experimentally induced Hansen's disease of rhesus, mangabey, and African green monkeys. In our long term evaluation of patients with Hansen's disease we have frequently found reduction of their intraocular pressure. Furthermore, we noted cha...
0C01
Timing and triggers of transient myocardial ischemia. Use of exercise tolerance testing and new techniques of ambulatory electrocardiographic monitoring to more objectively measure myocardial ischemia have enabled clinicians to better recognize the magnitude, timing and variable characteristics of transient ischemic e...
13C14
Plaque morphology and pathologic changes in arteries from patients dying after coronary balloon angioplasty Morphologic correlates of pathologic success or failure were studied at autopsy in 28 patients with 40 coronary arteries that had been subjected to balloon angioplasty. The presence of the following histologic...
13C14
Basic studies on a new material for inducing antitumor immune cells. Recently, adoptive immunotherapy for cancer with lymphokine activated killer (LAK) cells has been widely used experimentally. The therapy has several problems, including difficulty in handling, sterilization, and time consumption. To solve these pr...
3C04
Case report: severe ethylene glycol intoxication with normal osmolal gap--"a chilling thought". This is a case of a 23-year-old male presenting with altered sensorium, vomiting, and right flank pain. Despite a normal osmolal gap, he was found to be suffering from ethylene glycol intoxication. This little-described p...
20C21
Ionized calcium, parathormone, and mortality in critically ill surgical patients. A prospective study measured ionized calcium and parathormone sequentially at 48- to 72-hour intervals in 25 surgical intensive care unit patients. Twelve patients (48%) died at mean day 40 and median day 26. Levels of ionized calcium,...
11C12
Muscle relaxation rates in individuals susceptible to malignant hyperthermia. Muscle relaxation rate following a tetanic stimulus of adductor pollicis muscle was measured prospectively in 26 patients potentially susceptible to malignant hyperthermia (MH) the day before a muscle biopsy was obtained for MH in vitro scre...
22C23
Porcelain and resin veneers clinically evaluated: 2-year results. A clinical comparison of two different types of dental veneers--baked porcelain veneer and heat-and-pressure processed urethane resin veneer--was made after 2 years. Although the esthetic appearance and gingival response were equal for both systems, th...
22C23
Quantitative electromyography in polymyositis: a reappraisal. Manual analysis of motor unit action potentials (MUAPs) was performed in 33 patients with polymyositis of whom 16 were studied in the acute stage and 17 in the chronic stage. Contrary to common description of "myopathic potentials" as being of low amplitud...
4C05
Tumor necrosis factor: a putative mediator of the sick euthyroid syndrome in man. Tumor necrosis factor-alpha (TNF) is believed to be an important mediator in many diseases that are associated with the sick euthyroid syndrome. To investigate the effect of TNF on thyroid hormone metabolism, we performed a controlled s...
18C19
Prevalence of symptoms of Raynaud's phenomenon in general practice. OBJECTIVE--To investigate the prevalence of Raynaud's phenomenon in the populations of five general practices. DESIGN--Two populations studied. A questionnaire was given to all new patients attending five general practices over four weeks, and the s...
13C14
Ultrasonic evaluation of early carotid atherosclerosis. We investigated the prevalence of carotid atherosclerosis, including mild early lesions, and its association with cervical bruits and various risk factors (age, male sex, hypertension, hyperlipidemia, diabetes mellitus, obesity, and cigarette smoking) in 232 cons...
13C14
Lipiodol computerized tomography: how sensitive and specific is the technique in the diagnosis of hepatocellular carcinoma? Computerized tomography (CT) following the intra-arterial injection of Lipiodol (Lipiodol-CT) was performed on 60 patients suspected of having a hepatocellular carcinoma (HCC). Four main pattern...
3C04
Treatment of hirsutism with the pure antiandrogen flutamide. The effectiveness of the antiandrogen flutamide in combination with an oral contraceptive was studied in 20 patients with moderate to severe hirsutism. Eight patients had no previous therapy, whereas 12 had failed to respond to oral contraceptives, spironol...
16C17
Safety evaluation of PRP-D Haemophilus influenzae type b conjugate vaccine in children immunized at 18 months of age and older: follow-up study of 30,000 children. We evaluated the safety of the PRP-D conjugate Hib vaccine (ProHIBit, Connaught) in 29,309 children vaccinated at 18-60 months of age in the Southern Calif...
0C01
Cytomegalovirus infections in pediatric liver transplantation. From 1986 to 1989, 26 consecutive pediatric liver transplant recipients were followed up at The Hospital for Sick Children, Toronto, Canada. The patients were reviewed to assess the incidence of infection with cytomegalovirus, the severity of disease, and...
22C23
Intertrochanteric corrective osteotomy in slipped capital femoral epiphysis. A long-term follow-up study of 26 patients. The results of intertrochanteric corrective osteotomy in a series of 26 hips with moderate to severe chronic slipped capital femoral epiphysis are reported from follow-up studies in 1976 and 1986. ...
4C05
The use of rectus abdominis myocutaneous flaps following excision of vulvar cancer. Rectus abdominis myocutaneous flaps have been used in 16 women following radical excision of extensive vulvar cancer. In two women the procedure was part of the primary surgery, in 11 for recurrence of vulvar cancer and in three for s...
12C13
The impact of the U.S. Preventive Services Task Force guidelines on cancer screening: perspective from the National Cancer Institute. The U.S. Preventive Services Task Force evaluated the medical literature, utilizing strict criteria to judge the merits of experimental trials designed to show benefit in screening for...
3C04
Diminished incidence of severe rheumatoid arthritis associated with oral contraceptive use. It has been suggested that the negative association between rheumatoid arthritis (RA) and oral contraceptive (OC) use might be limited to the more severe forms of RA. To investigate this further, we studied 121 consecutive fem...
16C17
Crohn's disease in the city of Derby, 1951-85. An epidemiological survey of Crohn's disease in the city of Derby showed that the incidence of the condition increased from 0.7/10(5) per year between 1951 and 1955 to 6.67/10(5) per year between 1981 and 1985 but seemed to reach a plateau between 1976 and 1985. Large bo...
5C06
The detubularized right colonic segment as urinary reservoir: evolution of technique for continent diversion. Continent diversion of urine via a cecal-right colonic reservoir has been performed at our university hospital since 1977. Several modifications of surgical technique have been devised to prevent problems of ...
22C23
Search for epitope-specific antibody responses to the human immunodeficiency virus (HIV-1) envelope glycoproteins signifying resistance to disease development. It is essential for the development of strategies for prevention and therapy of human immunodeficiency virus (HIV-1) infections to define host factors playing ...
19C20
The effect of repetitive exercise on airway temperatures To determine if a relationship exists between intra-airway thermal events and the reduction in pulmonary mechanics that occur in asthmatics when they perform repetitive exercise, we recorded intrathoracic airstream temperatures in seven subjects during and afte...
19C20
Intraoperative radiation of canine carotid artery, internal jugular vein, and vagus nerve. Therapeutic applications in the management of advanced head and neck cancers. As a step in the application of intraoperative radiotherapy (IORT) for treating advanced head and neck cancers, preliminary information was obtained o...
3C04
Cefuroxime treatment failure of nontypable Haemophilus influenzae meningitis associated with alteration of penicillin-binding proteins. A 10-year-old boy presented with nuchal rigidity and cerebrospinal fluid (CSF) leukocytosis initially and again on day 6 of intravenous cefuroxime therapy (200 mg/kg/day). Both CSF s...
0C01
Functional and metabolic effects of bupivacaine and lignocaine in the rat heart-lung preparation. We have examined the effects of bupivacaine and lignocaine on myocardial metabolism in the rat isolated heart-lung preparation. Bupivacaine 1, 5 or 25 micrograms ml-1 or lignocaine 4, 20 or 100 micrograms ml-1 was admini...
22C23
Experience with a 'physiological' steroid replacement regimen for the establishment of a receptive endometrium in women with premature ovarian failure. Eighteen women with a premature menopause underwent assessment of serial serum oestradiol (E2) and progesterone levels and endometrial histology and function. Patient...
12C13
Platelet-activating factor. A putative mediator in central nervous system injury? Platelet-activating factor (1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a potent lipid autacoid produced by many cell types. Platelet-activating factor is produced by cerebellar granule cells in culture and has been extrac...
9C10
Short-term effect of hepatic arterial versus portal venous reperfusion on energy levels of liver tissue. The hepatic artery and the portal vein blood vary in flow, oxygenation, and hormonal content. It was uncertain which blood supply has a greater effect on the recuperative process of the hepatocytes in the ischemic...
13C14
Fine needle aspiration biopsy in the diagnosis and management of fibroadenoma of the breast. Cytological and histological biopsies were obtained on 75 breast lumps clinically diagnosed as fibroadenomas. Of these, 95 per cent of lesions were benign. In 51 (68 per cent) confirmed as fibroadenomas histologically, cytol...
3C04
Myxoid malignant fibrous histiocytoma of the bladder. Although the most common soft tissue sarcoma of adulthood, malignant fibrous histiocytoma (MFH) is an extremely rare tumor of the urinary bladder. Only three well-documented cases have been reported in the world literature. The patient presented in this report re...
11C12
Primary malignant melanoma of the lower respiratory tract. Report of a case and literature review. The authors report a case of primary bronchial malignant melanoma, occurring in a 34-year-old woman presenting with persistent cough. At bronchoscopic examination, a polypoid mass was found to occlude the left mainstem ...
3C04
Childhood stroke after minor neck trauma: case report. Cerebral infarction after minor trauma to the neck has rarely been reported. A case is presented of a child with trauma to the vertebrobasilar artery resulting in stroke. Computerized tomography scan and angiography results are presented. Despite two subsequent...
9C10
Using periodontal plastic surgery techniques. In the 1980s, mucogingival surgery evolved into periodontal plastic surgery with various techniques designed to produce root coverage in areas of marginal tissue recession, to augment deficient ridges, and to lengthen crowns in cases of excessive gingival display. Periodo...
6C07
Alcohol consumption by college undergraduates: current use and 10-year trends. In a carefully executed study with a high response rate, a random sample of 10% of the undergraduate student body at a rural New England university was surveyed as to the subjects' use of alcohol in 1987. Over 87% of the surveyed students ...
20C21
Development of a small caliber biologic vascular graft: evaluation of its antithrombogenicity and the early healing process. The authors previously showed that a small caliber xenograft using our crosslinking technique was applicable to aortocoronary bypass grafting. In this study of the graft, the antithrombogenicit...
22C23
Interrelationships between age, thyroid volume, thyroid nodularity, and thyroid function in patients with sporadic nontoxic goiter. PURPOSE: To test the hypothesis that during the natural history of sporadic nontoxic goiter (SNG), a diffuse goiter precedes a multinodular goiter with gradual development of autonomous t...
18C19
Chilblains (perniosis). Unfamiliarity of physicians with chilblains (perniosis) gives rise to unnecessary hospital admissions with expensive laboratory and radiologic evaluations and, at times, hazardous therapy. Seven cases of chilblains were seen in San Francisco from November 1986 through January 1987. The patien...
20C21
The restorative and surgical technique for the full maxillary subperiosteal implant. The edentulous atrophic maxilla represents one of the most challenging implant restorative opportunities. When prescribed within the appropriate diagnostic range and performed by a highly skilled and experienced practitioner, the ful...
4C05
Primary sclerosing cholangitis. Primary sclerosing cholangitis is a rare disease of unknown etiology. Sclerosis of the bile ducts may actually be the final result of multiple factors such as autoimmune, bacterial, congenital, drug, or viral injury. The most commonly associated diseases are ulcerative colitis and chr...
5C06
Effects of low perfusate Ca2+ concentration on newborn myocardial function after ischemia. A greater dependence on transsarcolemmal Ca2+ flux and immaturity of Ca2+ sequestration capacity may potentiate Ca2(+)-mediated reperfusion injury in the newborn myocardium. The effect of serum ionized Ca2+ concentration on lef...
13C14
Anaphylaxis following ingestion of a psyllium-containing cereal. Recently, psyllium hydrophilic mucilloid, a bulk-forming laxative, has been added to breakfast cereals for cholesterol-lowering effects. We report a case of a 60-year-old woman with no prior history of psyllium ingestion who developed anaphylactic sympt...
19C20
Effects of haem arginate on variegate porphyria. Four patients with variegate porphyria (VP) were treated with repeated haem arginate infusions daily for 4 days and then weekly for 4 weeks. After the initial four daily doses of haem arginate (haem 3 mg/kg), the excretion of faecal protoporphyrin (mean 579 nmol/g dry ...
16C17
Determinants and significance of diltiazem plasma concentrations after acute myocardial infarction. The Multicenter Diltiazem Postinfarction Trial Research Group. A total of 1,975 plasma diltiazem concentrations were obtained from 1,067 patients enrolled in a multicenter secondary intervention study of diltiazem after...
13C14
End of preview. Expand in Data Studio

Dataset Card for OHSUMED (23 classes, single-label TextGCN split)

Dataset Summary

This dataset is the canonical TextGCN Ohsumed protocol (Yao et al., AAAI 2019): 7,400 single-label documents, 3,357 train / 4,043 test, 23 MeSH disease chapters. Here the paper’s 3,357 training documents are split 3,021 / 336 so recipes that need a validation set can use it, or concatenate train+validation to recover the paper’s train count.

  • 7,400 MEDLINE records (year 1991), each with exactly one label.
  • Labels are the 23 MeSH disease chapters C01 to C23 (C01–C23), not the child terms of C14. C14 (Cardiovascular Diseases) is class 13 — one chapter in that set of 23. The document pool is Joachims/Moschitti’s 1991 cardiovascular-oriented subset; the label set remains those 23 top-level disease chapters.
  • This repository is a documented Parquet republication of dxgp/ohsumed (same 7,400 rows, previously without a card). It is not a replacement for the full ~348k IR collection (community-datasets/ohsumed), and it is not a byte-identical filter of that dump.

Single-label derivation. The Joachims/Moschitti 1991 pool is multi-label. Yao et al. (TextGCN, 2019) dropped every document with more than one of the 23 MeSH chapter labels and kept the 7,400 remaining single-label abstracts. No “first category wins” rule was applied here: this file is a documented copy of that filtered split (via dxgp/ohsumed), not a new filter of the 348k dump. An abstract that is medically both C04 and C14 is therefore absent unless it was already single-label in the source.

Why this version? The Hub hosts several incompatible “OHSUMED” objects (full multi-label IR dump, pickle CV folds, undocumented 7.4k CSV). If you compare accuracy to TextGCN, you need this split.

Recommended headline metric: macro-F1, not accuracy.

Provenance and Lineage

  1. OHSUMED (Hersh et al., 1994) — 348,566 MEDLINE references, 1987–1991.
  2. Joachims (1998) — first 20,000 records of 1991, 23-way categorization over MeSH chapters C01 to C23.
  3. Moschitti — packaged corpus ohsumed-all-docs.tar.gz / first-20k (13,929 unique after category selection, including multi-label).
  4. TextGCN (Yao et al., 2019) — keep single-label only → 7,400 docs; paper split 3,357 train / 4,043 test.
  5. dxgp/ohsumed — same 7,400 rows with a 336-row validation hold-out taken from the 3,357 train documents (3,021 + 336 = 3,357).
  6. This repo — Parquet + ClassLabel names C01–C23 + dataset card + NLM other license.

Bytes of text match dxgp (title + newline + space + abstract). No extra normalization.

Dataset Structure

Data Fields

  • text (string): title and abstract concatenated with newline then space (\n ). That separator is preserved on purpose so token-level baselines stay comparable to dxgp / common TextGCN reimplementations.
  • label (ClassLabel): integer 0–22 with names C01 to C23 (0→C01, …, 22→C23). C14 is name index 13, not the definition of the whole label set. Ordering matches MeSH codes in ascending order (verified: train[0] is duodenitis, label 5 = C06).

Label mapping

id MeSH code Category
0 C01 Bacterial Infections and Mycoses
1 C02 Virus Diseases
2 C03 Parasitic Diseases
3 C04 Neoplasms
4 C05 Musculoskeletal Diseases
5 C06 Digestive System Diseases
6 C07 Stomatognathic Diseases
7 C08 Respiratory Tract Diseases
8 C09 Otorhinolaryngologic Diseases
9 C10 Nervous System Diseases
10 C11 Eye Diseases
11 C12 Urologic and Male Genital Diseases
12 C13 Female Genital Diseases and Pregnancy Complications
13 C14 Cardiovascular Diseases
14 C15 Hemic and Lymphatic Diseases
15 C16 Neonatal Diseases and Abnormalities
16 C17 Skin and Connective Tissue Diseases
17 C18 Nutritional and Metabolic Diseases
18 C19 Endocrine Diseases
19 C20 Immunologic Diseases
20 C21 Disorders of Environmental Origin
21 C22 Animal Diseases
22 C23 Pathological Conditions, Signs and Symptoms

Splits

Split Rows Role
train 3,021 Paper train minus hold-out
validation 336 Hold-out from the paper’s 3,357 train docs (seed not published by dxgp)
test 4,043 Same count as the TextGCN test set; assignment is dxgp’s, not a re-draw of the 7,400 pool
Total 7,400 3,021 + 336 = 3,357 paper train

Comparability: this is the canonical TextGCN protocol (Yao et al., 2019): 7,400 single-label documents, 3,357 / 4,043 on 23 MeSH disease chapters. Here the paper’s 3,357 train docs are split 3,021 / 336 so that training recipes without a val set can concatenate train+validation. Test-set accuracy is therefore comparable to that literature on the same split counts.

Exact-text overlap between trainvalidation and test is 0 (7,400 unique strings). The files are a documented copy of dxgp/ohsumed; we did not redraw 3,357/4,043 from the 7,400 pool. We do not claim byte identity with Yao’s original archive: only that the Hub split preserves dxgp’s assignment, and that those counts match the paper.

The GNN literature often glosses this task as “23 cardiovascular disease categories”. That is incorrect. The 23 labels are MeSH disease chapters C01 to C23. C14 (Cardiovascular Diseases) is one class. Spot-check: duodenitis is C06 (Digestive).

Published accuracy / macro-F1 figures and the input-matching caveat are in Baseline results below.

Class counts (all splits, 7,400 rows)

MeSH Rows Share
C14 1,175 15.88%
C04 1,030 13.92%
C23 796 10.76%
C10 557 7.53%
C21 553 7.47%
C20 410 5.54%
C06 354 4.78%
C12 342 4.62%
C18 323 4.36%
C08 250 3.38%
C17 233 3.15%
C05 223 3.01%
C01 216 2.92%
C13 195 2.64%
C15 133 1.80%
C16 129 1.74%
C11 125 1.69%
C19 86 1.16%
C02 75 1.01%
C07 63 0.85%
C09 63 0.85%
C03 50 0.68%
C22 19 0.26%

Head/tail ratio (C14 vs C22) is about 62:1. Accuracy is misleading: a classifier that ignores the tail can still look respectable. Report macro-F1 and per-class F1. Categories are not mutually exclusive in reality (e.g. cardiac neoplasms are C04 and C14); forcing one label caps achievable top-1 accuracy. Top-3 is a more honest secondary metric.

Token length on BiomedBERT (train sample n=2,000): p50=237, p90=377, p95=422, p99=517, max=650. Training default --max_length is 448.

Uses

  • Research on single-label medical text classification and GNN/text-graph models, with numbers comparable to TextGCN on Ohsumed.

Out of scope

  • Clinical care, diagnosis, or any non-experimental library/clinical setting (OHSUMED / NLM conditions).
  • The full OHSUMED IR collection or multi-label MeSH assignment on ~348k records.
  • Claiming this 7,400-row split was reconstructed by filtering community-datasets/ohsumed (whitespace-normalized overlap is high but incomplete).

Limitations

C22 is never predicted

C22 - Animal Diseases scores F1 0.000 on all three seeds. With roughly a dozen test examples and similar training support, the model never learned to emit it: no input will receive this label. Any application that needs C22 detection must use another mechanism.

Metric consequence: a dead class costs 1/23 mechanically, i.e. 4.3 macro-F1 points. Hence dual reporting — 0.699 on 23 classes, 0.731 on the 22 classes with usable support.

Scores are not calibrated

Weighted cross-entropy (α = 0.5) used against class imbalance shifts calibration. Displayed scores are relative confidence scores, not probabilities. Temperature scaling on validation would be needed before any threshold-based use.

Intrinsic label ambiguity

Two distinct mechanisms coexist; they are not fixed the same way.

1. Granularity (C23). An abstract about a general clinical sign (hemorrhage, shock, pain, syncope…) will be routed to an organ chapter. Predictable behavior: C23 is a MeSH catch-all, not a domain; the model under-emits it (precision 0.592, recall 0.370; 264 outbound vs 107 inbound leaks). Demo users should know this.

2. Polyhierarchy. MeSH is not a tree. Illustration (app.py examples):

  • Lung Neoplasms: C04 and C08. The model predicts C08 (0.90) — legitimate; the corpus mostly labels “lung carcinoma / cancer” as C08.
  • Multiple Sclerosis: C10 and C20. The model predicts C20 (0.86); the corpus says C20 (train 10/12, test 15/15).

The top-1 → top-3 gap (0.774 → 0.933) mostly captures these two effects — not pure error — hence Top-3 in the demo.

Future work (formulation, not capacity)

The principled fix is not a better encoder but a better task formulation: multi-label or hierarchical labeling that does not force a choice between the sign (C23) and the organ, or between two cross-listed chapters. That is the conclusion the matrix supports.

Temporal drift

Abstracts from 1987–1991. Dated terminology, drugs, and protocols. No guarantee of generalization to contemporary biomedical literature.

Not a medical device

Bibliographic categorization only. No diagnostic or clinical decision-support use.

Schema and provenance

  • Schema is text + label only (TextGCN / dxgp comparability). There is no medline_ui, and title/abstract are not separate columns.
  • The 336-row validation hold-out seed was not published by dxgp. With 23 classes, C22 has at most one validation example. One class is 4.3 points of macro-F1, so checkpoint selection on this split is noisy; the 4,043-row test set is the reliable measure.
  • Bytes of text match dxgp; they are not a guaranteed exact subset of the 348k Hub dump. We do not claim byte identity with Yao’s original archive — only matching split counts and a documented copy of dxgp’s assignment.

Licensing and Usage

License tag: other (medline-research-use). Not CC-BY-NC or MIT (those Hub tags on related repos are unsourced).

MEDLINE-derived records follow NLM Terms and Conditions and NLM copyright guidance:

  • Courtesy: "Courtesy of the U.S. National Library of Medicine."
  • No endorsement: do not imply that NLM endorses this repository or any model trained on it.
  • Not current MEDLINE: this snapshot is 1987–1991 (this split: 1991 abstracts) and is incomplete relative to PubMed today.
  • Non-clinical: do not use for patient care or clinical decision-making.
  • Abstracts: may remain under publisher/author copyright. NLM does not grant a Creative Commons license on those texts.

Redistribution here is for NLP/IR research documentation of a long-standing public benchmark.

Baseline results

Fine-tune with train.py (checkpoint selection on eval macro-F1, weighted CE α=0.5, 5 epochs, max_length 448, effective batch 16). Hardware: RTX 3060 Laptop 6 GB. Test: 4,043 documents. Dataset revision pinned: c2e11d41da4d537366e75e02bc3b21a29a4978e0.

Model Size Acc Macro-F1 Macro-F1 excl. C22 Weighted-F1 Top-3
DistilBERT 66M 0.666 0.497 0.520 0.643 0.854
bert-base-uncased 110M 0.686 0.550 0.575 0.668 0.865
BiomedBERT 110M 0.774 0.699 0.731 0.766 0.933
BiomedBERT (TextGCN-preprocessed input) 110M 0.741 0.662 0.692 0.734 0.919

Decomposition: DistilBERT → bert-base = +2.0 acc / +5.3 macro-F1 (capacity); bert-base → BiomedBERT = +8.8 / +14.9 (domain).

Uncertainty

Two distinct dispersions are reported; they answer different questions:

  • Initialization variability — seeds 42 / 43 / 44, same split: accuracy 0.775 ± 0.003 · macro-F1 0.699 ± 0.005 · top-3 0.934 ± 0.002. This speaks to training stability.
  • Sampling variability — 95% bootstrap on the 4,043 test documents, 1,000 resamples: macro-F1 in [0.680, 0.715]. This is the one to use when comparing to a figure published elsewhere.

Released weights are seed 42 (accuracy 0.774, macro-F1 0.699). The table above reports the three-seed mean; a gap on the order of 0.001 between the two is expected.

Positioning on the TextGCN protocol

Method Input Accuracy Macro-F1
TF-IDF + logistic regression filtered 54.66
CNN-non-static filtered 58.44
RB-GAT (RoBERTa + BiGRU + GAT) filtered 71.48 67.90
BiomedBERT — paired comparison filtered 74.1 66.2
BiomedBERT — released model raw 77.4 69.9

Reading. Only the “paired” row is directly comparable to the cited work: it uses the same preprocessing. On that footing, BiomedBERT is slightly ahead in accuracy (+2.6) and slightly behind in macro-F1 (−1.7): the two approaches are at the same level. We claim no superiority.

The released model consumes raw text and posts higher absolute scores, but that number is not comparable to anything in the literature — it only shows what you get without degrading the input.

What TextGCN preprocessing costs a domain encoder

Absent from the cited literature: same BiomedBERT, same seed 42, same 3,357 / 4,043 split; only the input changes (preprocess_textgcn.py, NLTK stopwords + tokens with frequency < 5, vocabulary computed on train alone). From 0.774 / 0.699 (raw) to 0.741 / 0.662 (filtered): −3.3 accuracy points, −3.7 macro-F1.

Mechanism. The freq < 5 filter on ~3,357 training documents shrinks the kept vocabulary to 8,290 tokens (after stopword drop). Those are precisely the rare technical terms — where a WordPiece trained on PubMed beats a generalist vocabulary. The TextGCN protocol therefore systematically handicaps subword transformers relative to graph methods, which rely on frequent-word co-occurrences and lose less from that filtering. Confirming signature: macro-F1 drops more than accuracy (−3.7 vs −3.3), consistent with rare terms carrying mostly rare classes.

Scope of the comparison

Three models were compared, chosen to isolate domain effect at fixed architecture. This protocol shows that pretraining domain drives most of the gain — not that BiomedBERT is the best possible choice. Not evaluated: BioLinkBERT, recent long-context encoders, and a zero-shot LLM baseline that would set the floor without training. Contributions welcome.

Dominant confusions

Matrix (test, seed 42). Top pairs:

  • C23 → C14 (50) · C23 → C10 (42) · C23 → C21 / C02 → C20 (24 each)

C23 asymmetry. Strongly outbound flow: 264 C23→X vs 107 X→C23 (ratio 2.47). Precision 0.592, recall 0.370, F1 0.455 (n=419). The asymmetry makes the mechanism visible: the model is not symmetrically confusing C23 with something else — it under-emits C23. When it predicts C23 it is right six times out of ten; it only catches one third of true C23. Signature of a catch-all class learned to fire only when no organ signal is present. Second-largest macro-F1 hole after C22 (F1 0.000) — C23 is one of the three most frequent classes.

Headline figure: macro-F1 0.699 (23 classes). Diagnostic on the 21 well-formed classes — structural criterion fixed a priori, not “the two worst scores”: C22 has no usable support, C23 is not a domain but a residual chapter — : 0.744. A weak class for any other reason would stay in the average.

Dominant confusions are not domain-to-domain ambiguity but the residual nature of chapter C23 (Pathological Conditions, Signs and Symptoms), which absorbs signs and symptoms independently of the organ system. A C23-labeled abstract talks about a sign; its text is saturated with organ vocabulary; the model predicts the organ (hemorrhage/shock → C14, pain/coma → C10, post-traumatic signs → C21). That is a labeling granularity problem, not MeSH polyhierarchy.

Only one top pair matches a documented MeSH cross-listing: C02→C20. Of the 24 cases, 23 mention HIV / AIDS / immunodeficiency / HTLV — the 1987–1991 AIDS literature, cross-listed under Virus Diseases and Immunologic Deficiency Syndromes. C04↔C08 and C10↔C20 are rare in the matrix (4 and 1) despite appearing in the demo.

python inspect_dataset.py
python train.py --dataset_revision c2e11d41da4d537366e75e02bc3b21a29a4978e0 --max_train_samples 200 --epochs 1 --max_length 128
python train.py --dataset_revision c2e11d41da4d537366e75e02bc3b21a29a4978e0 --train_batch_size 8 --gradient_accumulation_steps 2 --eval_batch_size 16 --max_length 448
python train.py --model_name distilbert-base-uncased --output_dir outputs/distilbert-ohsumed23 --dataset_revision c2e11d41da4d537366e75e02bc3b21a29a4978e0 --train_batch_size 8 --gradient_accumulation_steps 2 --eval_batch_size 16
python train.py --model_name bert-base-uncased --output_dir outputs/bertbase-ohsumed23 --dataset_revision c2e11d41da4d537366e75e02bc3b21a29a4978e0 --train_batch_size 8 --gradient_accumulation_steps 2 --eval_batch_size 16
python eval_checkpoint.py --model_id outputs/biomedbert-ohsumed23/final
python analyze_results.py --run_dir outputs/biomedbert-ohsumed23

Demo: MODEL_ID=outputs/biomedbert-ohsumed23/final python app.py (PowerShell: $env:MODEL_ID="AxelNoun/biomedbert-ohsumed23"; python app.py).

Citation

Please cite the split, the original collection, and (if you discuss the 23-way 1991 task) Joachims:

@inproceedings{yao2019graph,
  title={Graph Convolutional Networks for Text Classification},
  author={Yao, Liang and Mao, Chengsheng and Luo, Yuan},
  booktitle={Proceedings of the AAAI Conference on Artificial Intelligence},
  volume={33},
  number={01},
  pages={7370--7377},
  year={2019}
}

@article{lv2024rbgat,
  title={{RB-GAT}: A Text Classification Model Based on {RoBERTa}-{BiGRU} with Graph {ATtention} Network},
  author={Lv, Shanshan and Dong, Jinming and Wang, Chao and Wang, Xianwei and Bao, Zhiyu},
  journal={Sensors},
  volume={24},
  number={11},
  pages={3365},
  year={2024}
}

@inproceedings{hersh1994ohsumed,
  title={{OHSUMED}: An Interactive Retrieval Evaluation and New Large Test Collection for Research},
  author={Hersh, William and Buckley, Chris and Leone, T. J. and Hickam, David},
  booktitle={Proceedings of the 17th Annual International {ACM} {SIGIR} Conference on Research and Development in Information Retrieval},
  pages={192--201},
  year={1994}
}

@inproceedings{joachims1998text,
  title={Text Categorization with Support Vector Machines: Learning with Many Relevant Features},
  author={Joachims, Thorsten},
  booktitle={Machine Learning: {ECML}-98},
  pages={137--142},
  year={1998},
  publisher={Springer}
}
Downloads last month
52

Models trained or fine-tuned on AxelNoun/ohsumed-23-single-label