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9 values
esm2 650m
esm2_t33_650m
null
esm2-650m
esm2_t33_650m
null
facebook esm2 650m
esm2_t33_650m
null
esm2 default
esm2_t33_650m
Canonical default ESM-2
esm2 3b
esm2_t36_3b
null
esm2-3b
esm2_t36_3b
null
facebook esm2 3b
esm2_t36_3b
null
esm2 15b
esm2_t48_15b
null
esm2 8m
esm2_t6_8m
null
esm2 35m
esm2_t12_35m
null
esm2 150m
esm2_t30_150m
null
esm1v
esm1v_650m
Defaults to model 1 of 5-ensemble
esm-1v
esm1v_650m
null
esm1v 650m
esm1v_650m
null
esm cambrian
esmc_300m
null
esmc
esmc_300m
Defaults to 300M variant
esmc 300m
esmc_300m
null
esm3
esm3_sm_open
Defaults to open 1.4B
esm3 small open
esm3_sm_open
null
esm3 1.4b
esm3_sm_open
null
evolutionaryscale esm3
esm3_sm_open
null
esmfold
esmfold_v1
null
esm fold
esmfold_v1
null
esm inverse folding
esm_if1
null
esm-if1
esm_if1
null
esm if1
esm_if1
null
boltzgen
boltzgen_1
null
boltz 2
boltz_2
null
boltz2
boltz_2
null
la proteina
nv_la_proteina
null
nvidia la proteina
nv_la_proteina
null
nv la proteina
nv_la_proteina
null
dplm 150m
dplm_150m
null
dplm 650m
dplm_650m
null
dplm 3b
dplm_3b
null
dplm2
dplm2_150m
Defaults to 150M
dplm2 150m
dplm2_150m
null
prot t5
prot_t5_xl_enc
Defaults to encoder-only for embedding use
prot t5 xl
prot_t5_xl
null
prot bert
prot_bert
null
protbert
prot_bert
null
ankh3
ankh3_large
Defaults to large
ankh3 large
ankh3_large
null
ankh3 xl
ankh3_xl
null
saprot
saprot_650m
null
saprot 650m
saprot_650m
null
tranception
tranception
null
protgpt2
protgpt2
null
prot gpt2
protgpt2
null
nucleotide transformer
nucleotide_transformer_v2_500m
Defaults to v2 500M multi-species
nt v2 500m
nucleotide_transformer_v2_500m
null
biomedbert
biomedbert_base
null
pubmedbert
biomedbert_base
Same model, different common name
biobert
biobert_base
null

BIIE-AI Protein Model Registry

A curated, structured registry of protein language models (PLMs), diffusion generators, structure predictors, inverse folding models, nucleotide language models, and biomedical NLP models.

Canonical local source: registry_src/models.jsonl (one record per line, edit here) Published format: Parquet (generated by scripts/build_parquet.py) Schema: schema/model_registry.schema.json Selection policy: registry_src/selection_policy.yaml

Dataset configs

Config Description
models One row per model — all registry fields
aliases Natural-language aliases → registry_id mappings
benchmarks Task/metric/value evaluation results (populated over time)

Key fields

Field Description
registry_id Unique snake_case identifier
hf_repo_id HuggingFace Hub org/model path
category Functional type (see taxonomy.md)
primary_tasks Main use cases
compute_tier GPU requirements
commercial_use Licensing assessment
selection_tags Tags used by the model-selection skill for routing

Workflow

# Edit registry
vim registry_src/models.jsonl

# Validate
python scripts/validate_registry.py

# Build Parquet
python scripts/build_parquet.py

# Sync live HF metadata (downloads, likes, gating)
python scripts/refresh_hf_metadata.py

# Publish to this repo
HF_TOKEN=hf_... python scripts/publish_to_hub.py

Taxonomy reference

See docs/taxonomy.md for all enum definitions (category, architecture_type, compute_tier, commercial_use, etc.).

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