true_melting_point / README.md
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metadata
license: cdla-permissive-2.0
task_categories:
  - tabular-regression
pretty_name: true_melting_point
tags:
  - tabular
  - proteomics
  - regression
  - Biomedical
  - Benchmark
  - cds-seq
configs:
  - config_name: true_melting_point
    data_files:
      - split: train
        path: data/train.parquet
      - split: validation
        path: data/val.parquet
      - split: test
        path: data/test.parquet
dataset_info:
  description: >-
    Sequence-level regression task predicting the melting temperature of
    proteins. Data originates from the Thermostability Atlas, compiled via a
    mass spectrometry-based proteomic approach. Splits follow the 'mixed'
    strategy from FLIP: sequences are clustered at 20% identity, with 80% of
    clusters assigned to train and 20% to test, avoiding over-emphasis of large
    clusters. Features are mean-pooled ESM-2 (esm2_t12_35M_UR50D) sequence
    embeddings.