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Human Spatial Transcriptomics Multi-organ Multi-platform Collection

This dataset provides a cleaned human spatial transcriptomics collection in .h5ad format. The released archive, Homo_sapiens_h5ad_flat.zip, contains 1,155 .h5ad files gathered into a flat archive for convenient download and reuse.

Dataset Summary

The collection covers Homo sapiens spatial transcriptomics data across multiple organs and experimental platforms. According to the accompanying internal statistics report, the human subset contains 28,050,110 spatial spots across 1,216 files/slices in the source statistics. The uploaded archive contains the cleaned .h5ad subset as 1,155 files.

Platforms

Platform Spots Percentage Files
MERFISH 10,334,462 36.84% 19
VisiumHD 8,686,473 30.97% 15
Xenium 4,704,330 16.77% 18
10X Visium 3,610,266 12.87% 1,129
Slide-seqV2 714,579 2.55% 35

Organ Coverage

The dataset spans a broad set of human tissues and anatomical categories, including unknown/unannotated samples, uterus, colon, lung, liver, prostate, tonsil, ovary, skin, breast, pancreas, heart, lymph node, kidney, brain, thymus, bone marrow, spinal cord, gland, embryo, intestine, placenta, oral mucosa, spleen, blood vessels, head and neck, cervix, stomach, tumor, synovial tissue, muscle, and bladder.

Top organ categories by spots include:

Organ Spots Percentage Files
Unknown 8,733,674 31.14% 30
Uterus 2,370,993 8.45% 15
Colon 2,307,710 8.23% 45
Lung 2,281,167 8.13% 106
Liver 1,825,259 6.51% 87
Prostate 1,780,803 6.35% 34
Tonsil 1,376,446 4.91% 2
Ovary 1,216,193 4.34% 43
Skin 1,172,313 4.18% 166
Breast 979,761 3.49% 68

Files

  • Homo_sapiens_h5ad_flat.zip: flat zip archive containing 1,155 cleaned human .h5ad files.

Notes

The uploaded archive includes only the cleaned dataset files. Summary statistics were used to describe the dataset card but are not uploaded as separate files.

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