instruction
stringlengths
34
186
input
stringlengths
2.02k
93.8k
output
stringlengths
2
418
meta_questiontype
stringclasses
6 values
meta_inputlicense
stringclasses
6 values
meta_pmid
stringlengths
8
8
meta_safetyreportid
int64
9.51M
21M
meta_articlepubdate
stringlengths
4
10
What was the dosage of drug 'DOXORUBICIN'?
Ifosfamide-induced nephrogenic diabetes insipidus responsive to supraphysiologic doses of intravenous desmopressin. Nephrogenic diabetes insipidus (DI) refers to the reduction in the ability of the kidney to concentrate urine, which can be caused by partial or complete resistance at the site of action of anti-diuretic ...
SIX CYCLE
DrugDosageText
CC BY
34235046
19,748,757
2021
What was the outcome of reaction 'Acute kidney injury'?
Ifosfamide-induced nephrogenic diabetes insipidus responsive to supraphysiologic doses of intravenous desmopressin. Nephrogenic diabetes insipidus (DI) refers to the reduction in the ability of the kidney to concentrate urine, which can be caused by partial or complete resistance at the site of action of anti-diuretic ...
Recovered
ReactionOutcome
CC BY
34235046
20,008,568
2021
What was the outcome of reaction 'Fanconi syndrome acquired'?
Ifosfamide-induced nephrogenic diabetes insipidus responsive to supraphysiologic doses of intravenous desmopressin. Nephrogenic diabetes insipidus (DI) refers to the reduction in the ability of the kidney to concentrate urine, which can be caused by partial or complete resistance at the site of action of anti-diuretic ...
Recovered
ReactionOutcome
CC BY
34235046
20,008,568
2021
What was the outcome of reaction 'Fanconi syndrome'?
Ifosfamide-induced nephrogenic diabetes insipidus responsive to supraphysiologic doses of intravenous desmopressin. Nephrogenic diabetes insipidus (DI) refers to the reduction in the ability of the kidney to concentrate urine, which can be caused by partial or complete resistance at the site of action of anti-diuretic ...
Recovered
ReactionOutcome
CC BY
34235046
19,963,422
2021
What was the outcome of reaction 'Metabolic acidosis'?
Ifosfamide-induced nephrogenic diabetes insipidus responsive to supraphysiologic doses of intravenous desmopressin. Nephrogenic diabetes insipidus (DI) refers to the reduction in the ability of the kidney to concentrate urine, which can be caused by partial or complete resistance at the site of action of anti-diuretic ...
Recovered
ReactionOutcome
CC BY
34235046
20,008,568
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Anaphylactic reaction'.
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
ACETAMINOPHEN, IBANDRONATE SODIUM
DrugsGivenReaction
CC BY-NC
34235121
19,644,257
2021-06
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Nausea'.
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
ACETAMINOPHEN, IBANDRONATE SODIUM
DrugsGivenReaction
CC BY-NC
34235121
19,644,257
2021-06
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Off label use'.
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
ACETAMINOPHEN, IBANDRONATE SODIUM
DrugsGivenReaction
CC BY-NC
34235121
19,644,257
2021-06
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Product use in unapproved indication'.
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
ACETAMINOPHEN, IBANDRONATE SODIUM
DrugsGivenReaction
CC BY-NC
34235121
19,644,257
2021-06
What was the administration route of drug 'ACETAMINOPHEN'?
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
Oral
DrugAdministrationRoute
CC BY-NC
34235121
19,644,257
2021-06
What was the administration route of drug 'IBANDRONATE SODIUM'?
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
Oral
DrugAdministrationRoute
CC BY-NC
34235121
19,644,257
2021-06
What was the dosage of drug 'IBANDRONATE SODIUM'?
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
150 mg (milligrams).
DrugDosage
CC BY-NC
34235121
19,644,257
2021-06
What was the outcome of reaction 'Anaphylactic reaction'?
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
Recovered
ReactionOutcome
CC BY-NC
34235121
19,644,257
2021-06
What was the outcome of reaction 'Nausea'?
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
Recovered
ReactionOutcome
CC BY-NC
34235121
19,644,257
2021-06
What was the outcome of reaction 'Off label use'?
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
Recovered
ReactionOutcome
CC BY-NC
34235121
19,644,257
2021-06
What was the outcome of reaction 'Product use in unapproved indication'?
Acetaminophen-induced anaphylaxis: a case report. Acetaminophen is known to be generally safe, and the occurrence of anaphylaxis due to acetaminophen has been rarely reported. We report a case of acetaminophen-induced anaphylaxis in a healthy male subject who participated in a clinical trial on the pharmacokinetics of ...
Recovered
ReactionOutcome
CC BY-NC
34235121
19,644,257
2021-06
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug resistance'.
Laser interstitial thermal therapy for NPRL3-related epilepsy with multiple seizure foci: A case report. Introduction: NPRL3 gene mutations cause autosomal dominant familial focal epilepsy of variable foci (FFEVF) and is characterized by focal epilepsy arising from different brain regions including temporal, frontal, p...
CLOBAZAM, LAMOTRIGINE, LEVETIRACETAM, OXCARBAZEPINE, VALPROIC ACID, ZONISAMIDE
DrugsGivenReaction
CC BY-NC-ND
34235417
20,204,726
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Therapeutic response decreased'.
Laser interstitial thermal therapy for NPRL3-related epilepsy with multiple seizure foci: A case report. Introduction: NPRL3 gene mutations cause autosomal dominant familial focal epilepsy of variable foci (FFEVF) and is characterized by focal epilepsy arising from different brain regions including temporal, frontal, p...
CLOBAZAM, LAMOTRIGINE, LEVETIRACETAM, OXCARBAZEPINE, VALPROIC ACID, ZONISAMIDE
DrugsGivenReaction
CC BY-NC-ND
34235417
20,205,592
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Coagulopathy'.
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
LEVETIRACETAM
DrugsGivenReaction
CC BY-NC-ND
34235418
19,574,707
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug-induced liver injury'.
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
LEVETIRACETAM
DrugsGivenReaction
CC BY-NC-ND
34235418
19,574,707
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hepatotoxicity'.
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
LEVETIRACETAM
DrugsGivenReaction
CC BY-NC-ND
34235418
19,574,707
2021
What is the weight of the patient?
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
150 kg.
Weight
CC BY-NC-ND
34235418
19,575,008
2021
What was the administration route of drug 'LEVETIRACETAM'?
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
Oral
DrugAdministrationRoute
CC BY-NC-ND
34235418
19,575,008
2021
What was the dosage of drug 'LEVETIRACETAM'?
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
500 mg (milligrams).
DrugDosage
CC BY-NC-ND
34235418
19,574,707
2021
What was the outcome of reaction 'Coagulopathy'?
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
Recovered
ReactionOutcome
CC BY-NC-ND
34235418
19,574,707
2021
What was the outcome of reaction 'Drug-induced liver injury'?
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
Recovered
ReactionOutcome
CC BY-NC-ND
34235418
19,574,707
2021
What was the outcome of reaction 'Hepatotoxicity'?
Severe drug-induced liver injury caused by levetiracetam - A case report and review of the literature. Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-do...
Recovered
ReactionOutcome
CC BY-NC-ND
34235418
19,574,707
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Condition aggravated'.
Novel Use of Extracorporeal Blood Purification for Treatment of Severe, Refractory Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy-A Case Report. BACKGROUND Chimeric antigen receptor T-cell therapies (CAR-T) are transforming the treatment of B-cell leukemias and lymphomas. Cytokine release syndrome and imm...
METHYLPREDNISOLONE
DrugsGivenReaction
CC BY-NC-ND
34235458
19,624,086
2021-07
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Encephalopathy'.
Novel Use of Extracorporeal Blood Purification for Treatment of Severe, Refractory Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy-A Case Report. BACKGROUND Chimeric antigen receptor T-cell therapies (CAR-T) are transforming the treatment of B-cell leukemias and lymphomas. Cytokine release syndrome and imm...
METHYLPREDNISOLONE
DrugsGivenReaction
CC BY-NC-ND
34235458
19,624,086
2021-07
What was the outcome of reaction 'Condition aggravated'?
Novel Use of Extracorporeal Blood Purification for Treatment of Severe, Refractory Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy-A Case Report. BACKGROUND Chimeric antigen receptor T-cell therapies (CAR-T) are transforming the treatment of B-cell leukemias and lymphomas. Cytokine release syndrome and imm...
Recovered
ReactionOutcome
CC BY-NC-ND
34235458
19,624,086
2021-07
What was the outcome of reaction 'Encephalopathy'?
Novel Use of Extracorporeal Blood Purification for Treatment of Severe, Refractory Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy-A Case Report. BACKGROUND Chimeric antigen receptor T-cell therapies (CAR-T) are transforming the treatment of B-cell leukemias and lymphomas. Cytokine release syndrome and imm...
Recovered
ReactionOutcome
CC BY-NC-ND
34235458
19,624,086
2021-07
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Metastatic malignant melanoma'.
False positive FDG uptake in melanoma patients treated with talimogene laherparepvec (T-VEC). Talimogene laherparepvec (T-VEC) is a genetically modified herpes simplex virus-1-based oncolytic immunotherapy and has been approved for the local treatment of unresectable (stage IIIB/C and IVM1a) cutaneous melanoma. During ...
TALIMOGENE LAHERPAREPVEC
DrugsGivenReaction
CC BY
34235758
19,574,965
2021-12
What was the dosage of drug 'TALIMOGENE LAHERPAREPVEC'?
False positive FDG uptake in melanoma patients treated with talimogene laherparepvec (T-VEC). Talimogene laherparepvec (T-VEC) is a genetically modified herpes simplex virus-1-based oncolytic immunotherapy and has been approved for the local treatment of unresectable (stage IIIB/C and IVM1a) cutaneous melanoma. During ...
UNK (MEDIAN OF 2 ML)
DrugDosageText
CC BY
34235758
19,574,965
2021-12
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hypoglycaemia'.
A novel approach to a rare case of non-islet cell hypoglycaemia. Insulin autoimmune syndrome (IAS) is a rare cause of non-islet cell hypoglycaemia. Treatment of this condition is complex and typically involves long-term use of glucocorticoids. Immunotherapy may provide an alternative in the management of this autoimmun...
SILDENAFIL, TADALAFIL
DrugsGivenReaction
CC BY-NC-ND
34236039
20,245,282
2021-07-01
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Prescription drug used without a prescription'.
A novel approach to a rare case of non-islet cell hypoglycaemia. Insulin autoimmune syndrome (IAS) is a rare cause of non-islet cell hypoglycaemia. Treatment of this condition is complex and typically involves long-term use of glucocorticoids. Immunotherapy may provide an alternative in the management of this autoimmun...
SILDENAFIL, TADALAFIL
DrugsGivenReaction
CC BY-NC-ND
34236039
20,245,282
2021-07-01
What was the outcome of reaction 'Generalised tonic-clonic seizure'?
A novel approach to a rare case of non-islet cell hypoglycaemia. Insulin autoimmune syndrome (IAS) is a rare cause of non-islet cell hypoglycaemia. Treatment of this condition is complex and typically involves long-term use of glucocorticoids. Immunotherapy may provide an alternative in the management of this autoimmun...
Recovered
ReactionOutcome
CC BY-NC-ND
34236039
20,248,110
2021-07-01
What was the outcome of reaction 'Hyperinsulinaemic hypoglycaemia'?
A novel approach to a rare case of non-islet cell hypoglycaemia. Insulin autoimmune syndrome (IAS) is a rare cause of non-islet cell hypoglycaemia. Treatment of this condition is complex and typically involves long-term use of glucocorticoids. Immunotherapy may provide an alternative in the management of this autoimmun...
Recovered
ReactionOutcome
CC BY-NC-ND
34236039
20,248,110
2021-07-01
What was the outcome of reaction 'Hypoglycaemia'?
A novel approach to a rare case of non-islet cell hypoglycaemia. Insulin autoimmune syndrome (IAS) is a rare cause of non-islet cell hypoglycaemia. Treatment of this condition is complex and typically involves long-term use of glucocorticoids. Immunotherapy may provide an alternative in the management of this autoimmun...
Recovered
ReactionOutcome
CC BY-NC-ND
34236039
20,245,282
2021-07-01
What was the outcome of reaction 'Intentional product misuse'?
A novel approach to a rare case of non-islet cell hypoglycaemia. Insulin autoimmune syndrome (IAS) is a rare cause of non-islet cell hypoglycaemia. Treatment of this condition is complex and typically involves long-term use of glucocorticoids. Immunotherapy may provide an alternative in the management of this autoimmun...
Recovered
ReactionOutcome
CC BY-NC-ND
34236039
20,256,925
2021-07-01
What was the outcome of reaction 'Self-medication'?
A novel approach to a rare case of non-islet cell hypoglycaemia. Insulin autoimmune syndrome (IAS) is a rare cause of non-islet cell hypoglycaemia. Treatment of this condition is complex and typically involves long-term use of glucocorticoids. Immunotherapy may provide an alternative in the management of this autoimmun...
Recovered
ReactionOutcome
CC BY-NC-ND
34236039
20,338,233
2021-07-01
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Product use in unapproved indication'.
Successful use of montelukast in eosinophilic gastroenteritis: a case report and a literature review. BACKGROUND Eosinophilic gastrointestinal disorders, also known as eosinophilic gastroenteritis, are rare inflammatory conditions characterized by eosinophilic infiltration of different parts of the gastrointestinal tra...
MONTELUKAST SODIUM
DrugsGivenReaction
CC BY
34238222
19,612,517
2021-07-08
What was the administration route of drug 'MONTELUKAST SODIUM'?
Successful use of montelukast in eosinophilic gastroenteritis: a case report and a literature review. BACKGROUND Eosinophilic gastrointestinal disorders, also known as eosinophilic gastroenteritis, are rare inflammatory conditions characterized by eosinophilic infiltration of different parts of the gastrointestinal tra...
Oral
DrugAdministrationRoute
CC BY
34238222
19,612,517
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Follicular lymphoma'.
Small intestinal follicular lymphoma induced by methotrexate: a case report. BACKGROUND Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare but critical complication that develops in patients treated with MTX. Although MTX-LPD has been recently reported, the incidence of follicular lymphoma in the ...
METHOTREXATE SODIUM
DrugsGivenReaction
CC BY
34238226
15,494,786
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Intestinal obstruction'.
Small intestinal follicular lymphoma induced by methotrexate: a case report. BACKGROUND Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare but critical complication that develops in patients treated with MTX. Although MTX-LPD has been recently reported, the incidence of follicular lymphoma in the ...
METHOTREXATE SODIUM
DrugsGivenReaction
CC BY
34238226
15,494,786
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Lymphoproliferative disorder'.
Small intestinal follicular lymphoma induced by methotrexate: a case report. BACKGROUND Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare but critical complication that develops in patients treated with MTX. Although MTX-LPD has been recently reported, the incidence of follicular lymphoma in the ...
METHOTREXATE SODIUM
DrugsGivenReaction
CC BY
34238226
15,494,786
2021-07-08
What is the weight of the patient?
Small intestinal follicular lymphoma induced by methotrexate: a case report. BACKGROUND Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare but critical complication that develops in patients treated with MTX. Although MTX-LPD has been recently reported, the incidence of follicular lymphoma in the ...
53.2 kg.
Weight
CC BY
34238226
15,494,786
2021-07-08
What was the administration route of drug 'METHOTREXATE SODIUM'?
Small intestinal follicular lymphoma induced by methotrexate: a case report. BACKGROUND Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare but critical complication that develops in patients treated with MTX. Although MTX-LPD has been recently reported, the incidence of follicular lymphoma in the ...
Oral
DrugAdministrationRoute
CC BY
34238226
15,494,786
2021-07-08
What was the outcome of reaction 'Follicular lymphoma'?
Small intestinal follicular lymphoma induced by methotrexate: a case report. BACKGROUND Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare but critical complication that develops in patients treated with MTX. Although MTX-LPD has been recently reported, the incidence of follicular lymphoma in the ...
Recovered
ReactionOutcome
CC BY
34238226
15,494,786
2021-07-08
What was the outcome of reaction 'Intestinal obstruction'?
Small intestinal follicular lymphoma induced by methotrexate: a case report. BACKGROUND Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare but critical complication that develops in patients treated with MTX. Although MTX-LPD has been recently reported, the incidence of follicular lymphoma in the ...
Recovered
ReactionOutcome
CC BY
34238226
15,494,786
2021-07-08
What was the outcome of reaction 'Lymphoproliferative disorder'?
Small intestinal follicular lymphoma induced by methotrexate: a case report. BACKGROUND Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a rare but critical complication that develops in patients treated with MTX. Although MTX-LPD has been recently reported, the incidence of follicular lymphoma in the ...
Recovered
ReactionOutcome
CC BY
34238226
15,494,786
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Cough'.
Translation, transcultural adaptation and validation to Brazilian Portuguese of tools for adverse drug reaction assessment in children. Children are more vulnerable to adverse drug reactions (ADRs) due to complex changes in the body during the growth process and lack specific pharmacoepidemiologic studies. Causality an...
AZITHROMYCIN ANHYDROUS, CEFEPIME HYDROCHLORIDE
DrugsGivenReaction
CC BY
34238235
19,908,440
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Dermatitis diaper'.
Translation, transcultural adaptation and validation to Brazilian Portuguese of tools for adverse drug reaction assessment in children. Children are more vulnerable to adverse drug reactions (ADRs) due to complex changes in the body during the growth process and lack specific pharmacoepidemiologic studies. Causality an...
FLUCONAZOLE, PENICILLIN G, SULFAMETHOXAZOLE\TRIMETHOPRIM
DrugsGivenReaction
CC BY
34238235
19,908,511
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug reaction with eosinophilia and systemic symptoms'.
Translation, transcultural adaptation and validation to Brazilian Portuguese of tools for adverse drug reaction assessment in children. Children are more vulnerable to adverse drug reactions (ADRs) due to complex changes in the body during the growth process and lack specific pharmacoepidemiologic studies. Causality an...
CEFEPIME HYDROCHLORIDE, LINEZOLID, VANCOMYCIN
DrugsGivenReaction
CC BY
34238235
19,878,333
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Rash'.
Translation, transcultural adaptation and validation to Brazilian Portuguese of tools for adverse drug reaction assessment in children. Children are more vulnerable to adverse drug reactions (ADRs) due to complex changes in the body during the growth process and lack specific pharmacoepidemiologic studies. Causality an...
CEFEPIME HYDROCHLORIDE, VANCOMYCIN
DrugsGivenReaction
CC BY
34238235
19,907,135
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Red man syndrome'.
Translation, transcultural adaptation and validation to Brazilian Portuguese of tools for adverse drug reaction assessment in children. Children are more vulnerable to adverse drug reactions (ADRs) due to complex changes in the body during the growth process and lack specific pharmacoepidemiologic studies. Causality an...
VANCOMYCIN
DrugsGivenReaction
CC BY
34238235
19,908,520
2021-07-08
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Drug ineffective for unapproved indication'.
Variant Neo-Aortoiliac System Operation Using a Composite Conduit of Silver-Coated Dacron Graft and Autologous Femoral Veins: A Report of Two Cases. Aortic prosthesis infection is associated with significant morbidity and mortality rates. The introduction of the neo-aortoiliac system (NAIS) technique offers a new persp...
AMPICILLIN, ANIDULAFUNGIN, AVIBACTAM SODIUM\CEFTAZIDIME, DAPTOMYCIN, METRONIDAZOLE
DrugsGivenReaction
CC BY-NC
34238771
20,473,567
2021-07-09
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Sepsis'.
Variant Neo-Aortoiliac System Operation Using a Composite Conduit of Silver-Coated Dacron Graft and Autologous Femoral Veins: A Report of Two Cases. Aortic prosthesis infection is associated with significant morbidity and mortality rates. The introduction of the neo-aortoiliac system (NAIS) technique offers a new persp...
AMPICILLIN, ANIDULAFUNGIN, AVIBACTAM SODIUM\CEFTAZIDIME, DAPTOMYCIN, METRONIDAZOLE
DrugsGivenReaction
CC BY-NC
34238771
20,455,296
2021-07-09
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Treatment failure'.
Variant Neo-Aortoiliac System Operation Using a Composite Conduit of Silver-Coated Dacron Graft and Autologous Femoral Veins: A Report of Two Cases. Aortic prosthesis infection is associated with significant morbidity and mortality rates. The introduction of the neo-aortoiliac system (NAIS) technique offers a new persp...
AMPICILLIN, ANIDULAFUNGIN, AVIBACTAM SODIUM\CEFTAZIDIME, DAPTOMYCIN, METRONIDAZOLE
DrugsGivenReaction
CC BY-NC
34238771
20,455,296
2021-07-09
What was the outcome of reaction 'Drug ineffective'?
Variant Neo-Aortoiliac System Operation Using a Composite Conduit of Silver-Coated Dacron Graft and Autologous Femoral Veins: A Report of Two Cases. Aortic prosthesis infection is associated with significant morbidity and mortality rates. The introduction of the neo-aortoiliac system (NAIS) technique offers a new persp...
Fatal
ReactionOutcome
CC BY-NC
34238771
20,473,484
2021-07-09
What was the outcome of reaction 'Sepsis'?
Variant Neo-Aortoiliac System Operation Using a Composite Conduit of Silver-Coated Dacron Graft and Autologous Femoral Veins: A Report of Two Cases. Aortic prosthesis infection is associated with significant morbidity and mortality rates. The introduction of the neo-aortoiliac system (NAIS) technique offers a new persp...
Fatal
ReactionOutcome
CC BY-NC
34238771
20,455,296
2021-07-09
What was the outcome of reaction 'Treatment failure'?
Variant Neo-Aortoiliac System Operation Using a Composite Conduit of Silver-Coated Dacron Graft and Autologous Femoral Veins: A Report of Two Cases. Aortic prosthesis infection is associated with significant morbidity and mortality rates. The introduction of the neo-aortoiliac system (NAIS) technique offers a new persp...
Fatal
ReactionOutcome
CC BY-NC
34238771
20,455,296
2021-07-09
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Steroid diabetes'.
The effect of liraglutide on insulin allergy in a patient with glucocorticoid-induced diabetes and multiple sclerosis. Glucocorticoid use may trigger secondary diabetes or exacerbate hyperglycemia in patients with diabetes mellitus (DM). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the tre...
HERBALS, INSULIN ASPART, INSULIN GLARGINE, INSULIN LISPRO, METHOTREXATE, METHYLPREDNISOLONE
DrugsGivenReaction
CC BY-NC-ND
34239182
20,317,024
2021-05
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Weight increased'.
The effect of liraglutide on insulin allergy in a patient with glucocorticoid-induced diabetes and multiple sclerosis. Glucocorticoid use may trigger secondary diabetes or exacerbate hyperglycemia in patients with diabetes mellitus (DM). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the tre...
HERBALS, INSULIN ASPART, INSULIN GLARGINE, INSULIN LISPRO, METHOTREXATE, METHYLPREDNISOLONE
DrugsGivenReaction
CC BY-NC-ND
34239182
20,317,024
2021-05
What is the weight of the patient?
The effect of liraglutide on insulin allergy in a patient with glucocorticoid-induced diabetes and multiple sclerosis. Glucocorticoid use may trigger secondary diabetes or exacerbate hyperglycemia in patients with diabetes mellitus (DM). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the tre...
85 kg.
Weight
CC BY-NC-ND
34239182
20,317,024
2021-05
What was the dosage of drug 'HERBALS'?
The effect of liraglutide on insulin allergy in a patient with glucocorticoid-induced diabetes and multiple sclerosis. Glucocorticoid use may trigger secondary diabetes or exacerbate hyperglycemia in patients with diabetes mellitus (DM). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the tre...
60 MILLIGRAM, QD
DrugDosageText
CC BY-NC-ND
34239182
20,317,024
2021-05
What was the dosage of drug 'INSULIN ASPART'?
The effect of liraglutide on insulin allergy in a patient with glucocorticoid-induced diabetes and multiple sclerosis. Glucocorticoid use may trigger secondary diabetes or exacerbate hyperglycemia in patients with diabetes mellitus (DM). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the tre...
60 INTERNATIONAL UNIT, QD GIVEN BEFORE THE THREE MEALS
DrugDosageText
CC BY-NC-ND
34239182
20,317,024
2021-05
What was the dosage of drug 'METHOTREXATE'?
The effect of liraglutide on insulin allergy in a patient with glucocorticoid-induced diabetes and multiple sclerosis. Glucocorticoid use may trigger secondary diabetes or exacerbate hyperglycemia in patients with diabetes mellitus (DM). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the tre...
7.5 MILLIGRAM PER WEEK
DrugDosageText
CC BY-NC-ND
34239182
20,317,024
2021-05
What was the outcome of reaction 'Steroid diabetes'?
The effect of liraglutide on insulin allergy in a patient with glucocorticoid-induced diabetes and multiple sclerosis. Glucocorticoid use may trigger secondary diabetes or exacerbate hyperglycemia in patients with diabetes mellitus (DM). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the tre...
Recovered
ReactionOutcome
CC BY-NC-ND
34239182
20,317,024
2021-05
What was the outcome of reaction 'Weight increased'?
The effect of liraglutide on insulin allergy in a patient with glucocorticoid-induced diabetes and multiple sclerosis. Glucocorticoid use may trigger secondary diabetes or exacerbate hyperglycemia in patients with diabetes mellitus (DM). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the tre...
Recovering
ReactionOutcome
CC BY-NC-ND
34239182
20,317,024
2021-05
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Acute coronary syndrome'.
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
AMIODARONE, ASPIRIN, AZITHROMYCIN ANHYDROUS, COLCHICINE, DOBUTAMINE HYDROCHLORIDE, FUROSEMIDE, HEPARIN SODIUM, METHYLPREDNISOLONE, NITRIC OXIDE, NOREPINEPHRINE, PIPERACILLIN SODIUM\TAZOBACTAM SODIUM, PREDNISONE, TICAGRELOR, VANCOMYCIN
DrugsGivenReaction
CC BY
34239379
19,751,881
2021
What was the administration route of drug 'ASPIRIN'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
Oral
DrugAdministrationRoute
CC BY
34239379
19,751,881
2021
What was the administration route of drug 'HEPARIN SODIUM'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
34239379
19,751,881
2021
What was the administration route of drug 'METHYLPREDNISOLONE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
34239379
19,751,881
2021
What was the administration route of drug 'PREDNISONE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
Oral
DrugAdministrationRoute
CC BY
34239379
19,751,881
2021
What was the administration route of drug 'VANCOMYCIN'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
Intravenous (not otherwise specified)
DrugAdministrationRoute
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'AMIODARONE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
150 MG TO START, FOLLOWED BY 1 MG/MIN CONTINUOUS INFUSION
DrugDosageText
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'ASPIRIN'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
325 mg (milligrams).
DrugDosage
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'COLCHICINE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
.6 mg (milligrams).
DrugDosage
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'DOBUTAMINE HYDROCHLORIDE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
2.5 MICROG/KG/MIN (UP?TITRATED TO 5 MICROG/KG/MIN)
DrugDosageText
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'FUROSEMIDE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
20 MG/H
DrugDosageText
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'METHYLPREDNISOLONE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
125 mg (milligrams).
DrugDosage
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'NITRIC OXIDE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
10 PPM
DrugDosageText
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'NOREPINEPHRINE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
0.02?3.0 MICROG/KG/MIN
DrugDosageText
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'PIPERACILLIN SODIUM\TAZOBACTAM SODIUM'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
4.5 g (grams).
DrugDosage
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'PREDNISONE'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
50 mg (milligrams).
DrugDosage
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'TICAGRELOR'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
180 mg (milligrams).
DrugDosage
CC BY
34239379
19,751,881
2021
What was the dosage of drug 'VANCOMYCIN'?
Suspected COVID-19-Induced Myopericarditis. Background: The incidence of myocarditis in patients with coronavirus disease 2019 (COVID-19) remains unknown; however, increasing evidence links COVID-19 to cardiovascular complications such as arrhythmias, heart failure, cardiogenic shock, fulminant myocarditis, and cardiac...
1250 mg (milligrams).
DrugDosage
CC BY
34239379
19,751,881
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Atrial fibrillation'.
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
HEPARIN SODIUM
DrugsGivenReaction
CC BY
34239383
19,619,076
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Femoral artery embolism'.
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
HEPARIN SODIUM
DrugsGivenReaction
CC BY
34239383
19,656,273
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Heparin-induced thrombocytopenia'.
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
HEPARIN SODIUM
DrugsGivenReaction
CC BY
34239383
19,619,076
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Hypotension'.
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
HEPARIN SODIUM
DrugsGivenReaction
CC BY
34239383
19,619,076
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Mitral valve stenosis'.
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
HEPARIN SODIUM
DrugsGivenReaction
CC BY
34239383
19,619,076
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Peripheral artery occlusion'.
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
HEPARIN SODIUM
DrugsGivenReaction
CC BY
34239383
19,619,076
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Renal failure'.
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
HEPARIN SODIUM
DrugsGivenReaction
CC BY
34239383
19,619,076
2021
Give an alphabetized list of all active substances of drugs taken by the patient who experienced 'Renal tubular necrosis'.
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
HEPARIN SODIUM
DrugsGivenReaction
CC BY
34239383
19,619,076
2021
What was the outcome of reaction 'Atrial fibrillation'?
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
Recovered
ReactionOutcome
CC BY
34239383
19,619,076
2021
What was the outcome of reaction 'Femoral artery embolism'?
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
Recovering
ReactionOutcome
CC BY
34239383
19,656,273
2021
What was the outcome of reaction 'Heparin-induced thrombocytopenia'?
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
Recovered
ReactionOutcome
CC BY
34239383
19,619,076
2021
What was the outcome of reaction 'Mitral valve stenosis'?
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
Recovering
ReactionOutcome
CC BY
34239383
19,619,076
2021
What was the outcome of reaction 'Peripheral artery occlusion'?
Heparin-Induced Thrombocytopenia After Mitral Valve Replacement. Background: Heparin-induced thrombocytopenia (HIT) is a rare autoimmune reaction that involves a decrease in platelet count following heparin exposure and can be associated with life-threatening thrombosis. Because of their prolonged heparin exposure, pat...
Recovering
ReactionOutcome
CC BY
34239383
19,619,076
2021