Name stringlengths 4 229 | Def stringlengths 20 900 |
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kidney stroma development | the process whose specific outcome is the progression of the kidney stroma over time , from its formation to the mature structure . |
regulation of cd4 production | any process that modulates the frequency , rate or extent of the chemical reactions and pathways resulting in the formation of cd4 . |
receptor - mediated virion attachment to host cell | the process by which a virion attaches to a host cell by binding to a receptor on the host cell surface . |
fructose biosynthetic process | the chemical reactions and pathways resulting in the formation of fructose , the ketohexose arabino - 2 - hexulose . |
premeiotic dna replication preinitiation complex assembly | any dna replication preinitiation complex assembly that is involved in meiotic cell cycle . |
pyrimidine nucleotide transport | the directed movement of a pyrimidine nucleotide , any compound consisting of a pyrimidine nucleoside esterified with ( ortho ) phosphate , into , out of or within a cell . |
detection of hydrogen ion | the series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal . |
thymine / thymine mispair binding | interacting selectively and non - covalently with double - stranded dna containing a t / t mispair . |
chitosanase activity | catalysis of the endohydrolysis of beta - 1 , 4 - linkages between n - acetyl - d - glucosamine and d - glucosamine residues in a partly acetylated chitosan . |
proximal tubule development | the process whose specific outcome is the progression of the proximal tubule over time , from its formation to the mature structure . |
host cell golgi membrane | the lipid bilayer surrounding any of the compartments of the host cell golgi apparatus . |
cyanelle ribonuclease p complex | a ribonuclease p complex located in the cyanelle , where it catalyzes the 5' endonucleolytic cleavage of precursor trnas to yield mature trnas . |
reproductive senescence | a natural reduction in reproductive capacity with aging , often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones . |
2 - octaprenyl - 6 - hydroxyphenol methylase activity | catalysis of the reaction: 3 - ( all - trans - octaprenyl ) benzene - 1 , 2 - diol + s - adenosyl - l - methionine < = > h + + 2 - methoxy - 6 - ( all - trans - octaprenyl ) phenol + s - adenosyl - l - homocysteine . |
parkin - mediated stimulation of mitophagy in response to mitochondrial depolarization | a positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin - family molecule . |
negative regulation of axon extension involved in axon guidance | any process that stops , prevents , or reduces the frequency , rate or extent of axon extension involved in axon guidance . |
desensitization of g protein - coupled receptor signaling pathway by arrestin | the process that inhibits the signaling function of a g protein - coupled receptor by uncoupling the receptor from its downstream g proteins . |
regulation of spongiotrophoblast cell proliferation | any process that modulates the rate , frequency or extent of spongiotrophoblast cell proliferation . |
atpase - coupled xenobiotic transmembrane transporter activity | catalysis of the reaction: atp + h2o + xenobiotic ( in ) = adp + phosphate + xenobiotic ( out ) . |
regulation of helicase activity | any process that modulates the frequency , rate or extent of helicase activity . |
negative regulation of interleukin - 21 production | any process that stops , prevents , or reduces the frequency , rate , or extent of interleukin - 21 production . |
sclerotium development | the process whose specific outcome is the progression of the sclerotium over time , from its formation to the mature structure . |
oligopeptide transmembrane transporter activity | enables the transfer of oligopeptides from one side of a membrane to the other . |
myelination of anterior lateral line nerve axons | the formation of compact myelin sheaths around the axons of the anterior lateral line nerve . |
telomeric loop formation | the process in which linear telomeric dna is remodeled into duplex loops , by the invasion of a 3' single - stranded overhang into the duplex region . |
triethanolamine lyase activity | catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde . |
cytosolic valyl - trna aminoacylation | the process of coupling valine to valyl - trna in the cytosol , catalyzed by valyl - trna synthetase . |
regulation of gastric motility | any process that modulates the frequency , rate or extent of gastric motility . |
protein homotrimerization | the formation of a protein homotrimer , a macromolecular structure consisting of three noncovalently associated identical subunits . |
lipid tube assembly involved in organelle fission | the aggregation , arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission . |
endogenous drug catabolic process | the chemical reactions and pathways resulting in the breakdown of a drug that has originated internally within the cell or organism . |
interleukin - 20 receptor complex | a protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand . |
cyanelle intermembrane space | the region between the inner and outer lipid bilayers of the cyanelle envelope ; includes the peptidoglycan layer . |
obsolete cytoplasmic sequestering of protein involved in mitotic g2 dna damage checkpoint | obsolete .any cytoplasmic sequestering of protein that is involved in mitotic g2 dna damage checkpoint . |
type 1 member 1 taste receptor binding | interacting selectively and non - covalently with a type 1 member 1 taste receptor . |
negative regulation of t cell extravasation | any process that stops , prevents or reduces the frequency , rate or extent of t cell extravasation . |
right tetrad | set of four basal bodies found in giardia species ( trophozoite stage ) . |
alpha - farnesene synthase activity | catalysis of the reaction: 2 - trans , 6 - trans - farnesyl diphosphate = ( e , e ) - alpha - farnesene + diphosphate . |
1 - ( 5 - phosphoribosyl ) - 5 - [ ( 5 - phosphoribosylamino ) methylideneamino ] imidazole - 4 - carboxamide isomerase activity | catalysis of the reaction: 1 - ( 5 - phosphoribosyl ) - 5 - [ ( 5 - phosphoribosylamino ) methylideneamino ] imidazole - 4 - carboxamide = 5 - [ ( 5 - phospho - 1 - deoxy - d - ribulos - 1 - ylimino ) methylamino ] - 1 - ( 5 - phospho - d - ribosyl ) imidazole - 4 - carboxamide . |
g - protein beta / gamma - btk complex | a protein complex formed by the association of the bruton tyrosine protein kinase btk , which is implicated in mammalian x - linked immunodeficiencies , with the beta and gamma subunits of a heterotrimeric g protein . |
pre - mrna cleavage required for polyadenylation | the targeted , endonucleolytic cleavage of a pre - mrna , required for polyadenylation of the 3' end . |
protocatechuate 3 , 4 - dioxygenase activity | catalysis of the reaction: 3 , 4 - dihydroxybenzoate + o2 = 3 - carboxy - cis , cis - muconate . |
positive regulation of cyclic - nucleotide phosphodiesterase activity | any process that activates or increases the frequency , rate or extent of cyclic nucleotide phosphodiesterase activity , the catalysis of the reaction: nucleotide 3' , 5' - cyclic phosphate + h2o = nucleotide 5' - phosphate . |
negative regulation of dna - templated transcription , initiation | any process that stops , prevents , or reduces the frequency , rate or extent of dna - templated transcription initiation . |
negative regulation of mammary stem cell proliferation | any process that stops , prevents , or reduces the frequency , rate or extent of mammary stem cell proliferation . |
sterol transport | the directed movement of sterols into , out of or within a cell , or between cells , by means of some agent such as a transporter or pore . |
cellular response to selenium ion | any process that results in a change in state or activity of a cell ( in terms of movement , secretion , enzyme production , gene expression , etc . ) |
secalciferol 1 - monooxygenase activity | catalysis of the reaction:2 h ( + ) + o2 + 2 reduced [ adrenodoxin ] + secalciferol = calcitetrol + h2o + 2 oxidized [ adrenodoxin ] . |
cellular stress response to acid chemical | any process that results in a change in state or activity of a cell ( in terms of movement , secretion , enzyme production , gene expression , etc . ) |
mannose catabolic process | the chemical reactions and pathways resulting in the breakdown of mannose , the aldohexose manno - hexose , the c - 2 epimer of glucose . |
post - embryonic plant organ development | development , taking place during the post - embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions . |
cellular response to uv - c | any process that results in a change in state or activity of a cell ( in terms of movement , secretion , enzyme production , gene expression , etc . ) |
negative regulation of vacuolar transport | any process that stops , prevents or reduces the frequency , rate or extent of vacuolar transport . |
peptidyl - serine trans - autophosphorylation | the phosphorylation of a peptidyl - serine to form peptidyl - o - phospho - l - serine on an identical protein . |
antigen processing and presentation of lipid antigen via mhc class ib | the process in which an antigen - presenting cell expresses lipid antigen in association with an mhc class ib protein complex on its cell surface , including lipid extraction , degradation , and transport steps for the lipid antigen both prior to and following assembly with the mhc protein complex . |
left ventricular compact myocardium morphogenesis | the process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized . |
[ 1 - ( 2 - amino - 7 - methyl - 4 - oxo - 7 , 8 - dihydro - 3h - pteridin - 6 - yl ) ] ethyl - 4 - ( beta - d - ribofuranosyl ) aminobenzene 5' - phosphate synthase activity | catalysis of the reaction: 4 - ( beta - d - ribofuranosyl ) aminobenzene 5' - phosphate + [ 1 - ( 2 - amino - 7 - methyl - 4 - oxo - 7 , 8 - dihydro - 3h - pteridin - 6 - yl ) ] ethyl diphosphate = [ 1 - ( 2 - amino - 7 - methyl - 4 - oxo - 7 , 8 - dihydro - 3h - pteridin - 6 - yl ) ] ethyl - 4 - ( beta - d -... |
regulation of mitotic nuclear envelope disassembly | any process that modulates the frequency , rate or extent of mitotic nuclear envelope disassembly . |
trans - pentaprenyltranstransferase activity | catalysis of the reaction: all - trans - pentaprenyl diphosphate + isopentenyl diphosphate = all - trans - hexaprenyl diphosphate + diphosphate . |
peptidyl - alanine modification | the modification of peptidyl - alanine . |
cellular response to angiotensin | any process that results in a change in state or activity of a cell ( in terms of movement , secretion , enzyme production , gene expression , etc . ) |
aster | an array of microtubules emanating from a spindle pole mtoc that do not connect to kinetochores . |
positive regulation of toll - like receptor 2 signaling pathway | any process that activates or increases the frequency , rate , or extent of toll - like receptor 2 signaling pathway . |
( + ) - larreatricin metabolic process | the chemical reactions and pathways involving ( + ) - larreatricin . |
regulation of histone ubiquitination | any process that modulates the frequency , rate or extent of the addition of a ubiquitin group to a histone protein . |
obsolete diuresis | obsolete .the process of renal water excretion . |
cellular response to cell wall damage | any process that results in a change in state or activity of a cell ( in terms of movement , secretion , enzyme production , gene expression , etc . ) |
negative regulation of natural killer cell apoptotic process | any process that stops , prevents , or reduces the frequency , rate or extent of natural killer cell death by apoptotic process . |
gibberellin 20 - oxidase activity | catalysis of the oxidation of c - 20 gibberellins to form the corresponding c - 19 lactones . |
sodium ion binding | interacting selectively and non - covalently with sodium ions ( na + ) . |
stomatal complex formation | the process that gives rise to the stomatal complex . |
collecting duct development | the process whose specific outcome is the progression of a collecting duct over time , from its formation to the mature structure . |
gallate catabolic process | the chemical reactions and pathways resulting in the breakdown of gallate , the anion of gallic acid ( 3 , 4 , 5 - trihydroxybenzoic acid ) . |
regulation of central b cell deletion | any process that modulates the frequency , rate , or extent of central b cell deletion . |
bisulfite reduction | the chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite . |
nucleotide - excision repair , dna incision | a process that results in the endonucleolytic cleavage of the damaged strand of dna . |
formation of radial glial scaffolds | the formation of scaffolds from a radial glial cell . |
l - methionine biosynthetic process from homoserine via o - phospho - l - homoserine and cystathionine | the chemical reactions and pathways resulting in the formation of l - methionine from other compounds , including homoserine , via the intermediates o - phospho - l - homoserine and cystathionine . |
nadh dehydrogenase complex | an integral membrane complex that possesses nadh oxidoreductase activity . |
folate:anion antiporter activity | enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folate derivative ( out ) + anion ( in ) = folate derivative ( in ) + anion ( out ) . |
positive regulation of sorocarp stalk cell differentiation | any process that activates or increases the frequency , rate or extent of sorocarp stalk cell differentiation . |
starch utilization system complex assembly | the aggregation , arrangement and bonding together of the starch utilization system complex , a complex of cell envelope - associated proteins that degrades glycan . |
regulation of interleukin - 4 - mediated signaling pathway | any process that modulates the frequency , rate or extent of interleukin - 4 - mediated signaling pathway . |
hard palate morphogenesis | the developmental process by which a hard palate is generated and organized . |
mycocerosate synthase activity | catalysis of the reaction: acyl - coa + 7n h ( + ) + n methylmalonyl - coa + 2n nadph = n co ( 2 ) + n coa + n h ( 2 ) o + multi - methyl - branched acyl - coa + 2n nadp ( + ) . |
endoplasmic reticulum quality control compartment | a subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate . |
viral budding from golgi membrane | a viral budding that starts with formation of a membrane curvature in the host golgi membrane . |
dynactin complex | a 20s multiprotein assembly of total mass about 1 .2 mda that activates dynein - based activity in vivo . |
negative regulation of protein histidine kinase activity | any process that stops , prevents , or reduces the frequency , rate or extent of protein histidine kinase activity . |
activation of protein kinase b activity | any process that initiates the activity of the inactive enzyme protein kinase b . |
trna 4 - thiouridine biosynthesis | the processes whereby a uridine residue in a trna is converted to 4 - thiouridine . |
dinucleotide repeat insertion binding | interacting selectively and non - covalently with double - stranded dna containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats . |
sumo ligase activity | catalysis of the transfer of sumo to a substrate protein via the reaction x - sumo + s - - > x + s - sumo , where x is either an e2 or e3 enzyme , the x - sumo linkage is a thioester bond , and the s - sumo linkage is an isopeptide bond between the c - terminal amino acid of sumo and the epsilon - amino grou... |
integral component of postsynaptic specialization membrane of symmetric synapse | the component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane . |
follicular fluid formation in ovarian follicle antrum | the menstrual cycle process that results in the formation of one central cavity separating the oocyte / cumulus complex from mural granulosa and theca cells during the various stages of oogenesis . |
maintenance of neuroblast polarity | the maintenance of the apicobasal polarity of a neuroblast cell , a progenitor of the central nervous system . |
2 , 3 - diaminopropionate n - oxalyltransferase activity | catalysis of the reaction: 3 - amino - l - alanine + oxalyl - coa = n ( 3 ) - oxalyl - l - 2 , 3 - diaminopropanoate + coa . |
positive regulation of hematopoietic stem cell differentiation | any process that activates or increases the frequency , rate or extent of hematopoietic stem cell differentiation . |
obsolete activation of mapkkk ( pseudohyphal growth ) | obsolete .upregulation of mapkkk activity in the context of regulating pseudohyphal or invasive growth . |
triboa - glucoside methyltransferase activity | catalysis of the reaction: triboa - beta - d - glucoside + s - adenosyl - l - methionine < = > ( 2r ) - dimboa glucoside + s - adenosyl - l - homocysteine + h + . |
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