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223,600
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_find_input_files
def _find_input_files(var, out): """Find input files within the given CWL object. """ if isinstance(var, (list, tuple)): for x in var: out = _find_input_files(x, out) elif isinstance(var, dict): if var.get("class") == "File": out.append(var["path"]) ou...
python
def _find_input_files(var, out): """Find input files within the given CWL object. """ if isinstance(var, (list, tuple)): for x in var: out = _find_input_files(x, out) elif isinstance(var, dict): if var.get("class") == "File": out.append(var["path"]) ou...
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Find input files within the given CWL object.
[ "Find", "input", "files", "within", "the", "given", "CWL", "object", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L209-L221
223,601
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_read_from_cwlinput
def _read_from_cwlinput(in_file, work_dir, runtime, parallel, input_order, output_cwl_keys): """Read data records from a JSON dump of inputs. Avoids command line flattening of records. """ with open(in_file) as in_handle: inputs = json.load(in_handle) items_by_key = {} input_files = [] p...
python
def _read_from_cwlinput(in_file, work_dir, runtime, parallel, input_order, output_cwl_keys): """Read data records from a JSON dump of inputs. Avoids command line flattening of records. """ with open(in_file) as in_handle: inputs = json.load(in_handle) items_by_key = {} input_files = [] p...
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Read data records from a JSON dump of inputs. Avoids command line flattening of records.
[ "Read", "data", "records", "from", "a", "JSON", "dump", "of", "inputs", ".", "Avoids", "command", "line", "flattening", "of", "records", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L223-L249
223,602
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_maybe_nest_bare_single
def _maybe_nest_bare_single(items_by_key, parallel): """Nest single inputs to avoid confusing single items and lists like files. """ if (parallel == "multi-parallel" and (sum([1 for x in items_by_key.values() if not _is_nested_item(x)]) >= sum([1 for x in items_by_key.values() if _is_ne...
python
def _maybe_nest_bare_single(items_by_key, parallel): """Nest single inputs to avoid confusing single items and lists like files. """ if (parallel == "multi-parallel" and (sum([1 for x in items_by_key.values() if not _is_nested_item(x)]) >= sum([1 for x in items_by_key.values() if _is_ne...
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Nest single inputs to avoid confusing single items and lists like files.
[ "Nest", "single", "inputs", "to", "avoid", "confusing", "single", "items", "and", "lists", "like", "files", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L254-L265
223,603
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_check_for_single_nested
def _check_for_single_nested(target, items_by_key, input_order): """Check for single nested inputs that match our target count and unnest. Handles complex var inputs where some have an extra layer of nesting. """ out = utils.deepish_copy(items_by_key) for (k, t) in input_order.items(): if t...
python
def _check_for_single_nested(target, items_by_key, input_order): """Check for single nested inputs that match our target count and unnest. Handles complex var inputs where some have an extra layer of nesting. """ out = utils.deepish_copy(items_by_key) for (k, t) in input_order.items(): if t...
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Check for single nested inputs that match our target count and unnest. Handles complex var inputs where some have an extra layer of nesting.
[ "Check", "for", "single", "nested", "inputs", "that", "match", "our", "target", "count", "and", "unnest", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L273-L284
223,604
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_concat_records
def _concat_records(items_by_key, input_order): """Concatenate records into a single key to avoid merging. Handles heterogeneous records that will then be sorted out in the processing fuction. """ all_records = [] for (k, t) in input_order.items(): if t == "record": all_reco...
python
def _concat_records(items_by_key, input_order): """Concatenate records into a single key to avoid merging. Handles heterogeneous records that will then be sorted out in the processing fuction. """ all_records = [] for (k, t) in input_order.items(): if t == "record": all_reco...
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Concatenate records into a single key to avoid merging. Handles heterogeneous records that will then be sorted out in the processing fuction.
[ "Concatenate", "records", "into", "a", "single", "key", "to", "avoid", "merging", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L286-L306
223,605
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_nest_vars_in_rec
def _nest_vars_in_rec(var_items, rec_items, input_order, items_by_key, parallel): """Nest multiple variable inputs into a single record or list of batch records. Custom CWL implementations extract and merge these. """ num_items = var_items var_items = list(var_items)[0] if rec_items: re...
python
def _nest_vars_in_rec(var_items, rec_items, input_order, items_by_key, parallel): """Nest multiple variable inputs into a single record or list of batch records. Custom CWL implementations extract and merge these. """ num_items = var_items var_items = list(var_items)[0] if rec_items: re...
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Nest multiple variable inputs into a single record or list of batch records. Custom CWL implementations extract and merge these.
[ "Nest", "multiple", "variable", "inputs", "into", "a", "single", "record", "or", "list", "of", "batch", "records", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L364-L380
223,606
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_expand_rec_to_vars
def _expand_rec_to_vars(var_items, rec_items, input_order, items_by_key, parallel): """Expand record to apply to number of variants. Alternative approach to _nest_vars_in_rec to combining a single record with multiple variants. """ num_items = var_items var_items = list(var_items)[0] if rec...
python
def _expand_rec_to_vars(var_items, rec_items, input_order, items_by_key, parallel): """Expand record to apply to number of variants. Alternative approach to _nest_vars_in_rec to combining a single record with multiple variants. """ num_items = var_items var_items = list(var_items)[0] if rec...
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Expand record to apply to number of variants. Alternative approach to _nest_vars_in_rec to combining a single record with multiple variants.
[ "Expand", "record", "to", "apply", "to", "number", "of", "variants", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L382-L397
223,607
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_read_cwl_record
def _read_cwl_record(rec): """Read CWL records, handling multiple nesting and batching cases. """ keys = set([]) out = [] if isinstance(rec, dict): is_batched = all([isinstance(v, (list, tuple)) for v in rec.values()]) cur = [{} for _ in range(len(rec.values()[0]) if is_batched else ...
python
def _read_cwl_record(rec): """Read CWL records, handling multiple nesting and batching cases. """ keys = set([]) out = [] if isinstance(rec, dict): is_batched = all([isinstance(v, (list, tuple)) for v in rec.values()]) cur = [{} for _ in range(len(rec.values()[0]) if is_batched else ...
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Read CWL records, handling multiple nesting and batching cases.
[ "Read", "CWL", "records", "handling", "multiple", "nesting", "and", "batching", "cases", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L399-L425
223,608
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_finalize_cwl_in
def _finalize_cwl_in(data, work_dir, passed_keys, output_cwl_keys, runtime): """Finalize data object with inputs from CWL. """ data["dirs"] = {"work": work_dir} if not tz.get_in(["config", "algorithm"], data): if "config" not in data: data["config"] = {} data["config"]["algor...
python
def _finalize_cwl_in(data, work_dir, passed_keys, output_cwl_keys, runtime): """Finalize data object with inputs from CWL. """ data["dirs"] = {"work": work_dir} if not tz.get_in(["config", "algorithm"], data): if "config" not in data: data["config"] = {} data["config"]["algor...
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Finalize data object with inputs from CWL.
[ "Finalize", "data", "object", "with", "inputs", "from", "CWL", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L427-L442
223,609
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_convert_value
def _convert_value(val): """Handle multiple input type values. """ def _is_number(x, op): try: op(x) return True except ValueError: return False if isinstance(val, (list, tuple)): return [_convert_value(x) for x in val] elif val is None: ...
python
def _convert_value(val): """Handle multiple input type values. """ def _is_number(x, op): try: op(x) return True except ValueError: return False if isinstance(val, (list, tuple)): return [_convert_value(x) for x in val] elif val is None: ...
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Handle multiple input type values.
[ "Handle", "multiple", "input", "type", "values", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L444-L472
223,610
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_get_output_cwl_keys
def _get_output_cwl_keys(fnargs): """Retrieve output_cwl_keys from potentially nested input arguments. """ for d in utils.flatten(fnargs): if isinstance(d, dict) and d.get("output_cwl_keys"): return d["output_cwl_keys"] raise ValueError("Did not find output_cwl_keys in %s" % (pprint....
python
def _get_output_cwl_keys(fnargs): """Retrieve output_cwl_keys from potentially nested input arguments. """ for d in utils.flatten(fnargs): if isinstance(d, dict) and d.get("output_cwl_keys"): return d["output_cwl_keys"] raise ValueError("Did not find output_cwl_keys in %s" % (pprint....
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Retrieve output_cwl_keys from potentially nested input arguments.
[ "Retrieve", "output_cwl_keys", "from", "potentially", "nested", "input", "arguments", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L492-L498
223,611
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_combine_cwl_records
def _combine_cwl_records(recs, record_name, parallel): """Provide a list of nexted CWL records keyed by output key. Handles batches, where we return a list of records, and single items where we return one record. """ if parallel not in ["multi-batch", "single-split", "multi-combined", "batch-single...
python
def _combine_cwl_records(recs, record_name, parallel): """Provide a list of nexted CWL records keyed by output key. Handles batches, where we return a list of records, and single items where we return one record. """ if parallel not in ["multi-batch", "single-split", "multi-combined", "batch-single...
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Provide a list of nexted CWL records keyed by output key. Handles batches, where we return a list of records, and single items where we return one record.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L500-L510
223,612
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_collapse_to_cwl_record_single
def _collapse_to_cwl_record_single(data, want_attrs, input_files): """Convert a single sample into a CWL record. """ out = {} for key in want_attrs: key_parts = key.split("__") out[key] = _to_cwl(tz.get_in(key_parts, data), input_files) return out
python
def _collapse_to_cwl_record_single(data, want_attrs, input_files): """Convert a single sample into a CWL record. """ out = {} for key in want_attrs: key_parts = key.split("__") out[key] = _to_cwl(tz.get_in(key_parts, data), input_files) return out
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Convert a single sample into a CWL record.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L512-L519
223,613
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_nested_cwl_record
def _nested_cwl_record(xs, want_attrs, input_files): """Convert arbitrarily nested samples into a nested list of dictionaries. nests only at the record level, rather than within records. For batching a top level list is all of the batches and sub-lists are samples within the batch. """ if isins...
python
def _nested_cwl_record(xs, want_attrs, input_files): """Convert arbitrarily nested samples into a nested list of dictionaries. nests only at the record level, rather than within records. For batching a top level list is all of the batches and sub-lists are samples within the batch. """ if isins...
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Convert arbitrarily nested samples into a nested list of dictionaries. nests only at the record level, rather than within records. For batching a top level list is all of the batches and sub-lists are samples within the batch.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L521-L532
223,614
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_collapse_to_cwl_record
def _collapse_to_cwl_record(samples, want_attrs, input_files): """Convert nested samples from batches into a CWL record, based on input keys. """ input_keys = sorted(list(set().union(*[d["cwl_keys"] for d in samples])), key=lambda x: (-len(x), tuple(x))) out = {} for key in input_keys: if ke...
python
def _collapse_to_cwl_record(samples, want_attrs, input_files): """Convert nested samples from batches into a CWL record, based on input keys. """ input_keys = sorted(list(set().union(*[d["cwl_keys"] for d in samples])), key=lambda x: (-len(x), tuple(x))) out = {} for key in input_keys: if ke...
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Convert nested samples from batches into a CWL record, based on input keys.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L534-L550
223,615
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_file_and_exists
def _file_and_exists(val, input_files): """Check if an input is a file and exists. Checks both locally (staged) and from input files (re-passed but never localized). """ return ((os.path.exists(val) and os.path.isfile(val)) or val in input_files)
python
def _file_and_exists(val, input_files): """Check if an input is a file and exists. Checks both locally (staged) and from input files (re-passed but never localized). """ return ((os.path.exists(val) and os.path.isfile(val)) or val in input_files)
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Check if an input is a file and exists. Checks both locally (staged) and from input files (re-passed but never localized).
[ "Check", "if", "an", "input", "is", "a", "file", "and", "exists", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L552-L558
223,616
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_to_cwl
def _to_cwl(val, input_files): """Convert a value into CWL formatted JSON, handling files and complex things. """ if isinstance(val, six.string_types): if _file_and_exists(val, input_files): val = {"class": "File", "path": val} secondary = [] for idx in [".bai", "...
python
def _to_cwl(val, input_files): """Convert a value into CWL formatted JSON, handling files and complex things. """ if isinstance(val, six.string_types): if _file_and_exists(val, input_files): val = {"class": "File", "path": val} secondary = [] for idx in [".bai", "...
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Convert a value into CWL formatted JSON, handling files and complex things.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L560-L603
223,617
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_remove_duplicate_files
def _remove_duplicate_files(xs): """Remove files specified multiple times in a list. """ seen = set([]) out = [] for x in xs: if x["path"] not in seen: out.append(x) seen.add(x["path"]) return out
python
def _remove_duplicate_files(xs): """Remove files specified multiple times in a list. """ seen = set([]) out = [] for x in xs: if x["path"] not in seen: out.append(x) seen.add(x["path"]) return out
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Remove files specified multiple times in a list.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L605-L614
223,618
bcbio/bcbio-nextgen
bcbio/distributed/runfn.py
_update_nested
def _update_nested(key, val, data, allow_overwriting=False): """Update the data object, avoiding over-writing with nested dictionaries. """ if isinstance(val, dict): for sub_key, sub_val in val.items(): data = _update_nested(key + [sub_key], sub_val, data, allow_overwriting=allow_overwri...
python
def _update_nested(key, val, data, allow_overwriting=False): """Update the data object, avoiding over-writing with nested dictionaries. """ if isinstance(val, dict): for sub_key, sub_val in val.items(): data = _update_nested(key + [sub_key], sub_val, data, allow_overwriting=allow_overwri...
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Update the data object, avoiding over-writing with nested dictionaries.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/runfn.py#L623-L638
223,619
bcbio/bcbio-nextgen
bcbio/server/main.py
start
def start(args): """Run server with provided command line arguments. """ application = tornado.web.Application([(r"/run", run.get_handler(args)), (r"/status", run.StatusHandler)]) application.runmonitor = RunMonitor() application.listen(args.port) torna...
python
def start(args): """Run server with provided command line arguments. """ application = tornado.web.Application([(r"/run", run.get_handler(args)), (r"/status", run.StatusHandler)]) application.runmonitor = RunMonitor() application.listen(args.port) torna...
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Run server with provided command line arguments.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/server/main.py#L8-L15
223,620
bcbio/bcbio-nextgen
bcbio/server/main.py
add_subparser
def add_subparser(subparsers): """Add command line arguments as server subparser. """ parser = subparsers.add_parser("server", help="Run a bcbio-nextgen server allowing remote job execution.") parser.add_argument("-c", "--config", help=("Global YAML configuration file specifying system details." ...
python
def add_subparser(subparsers): """Add command line arguments as server subparser. """ parser = subparsers.add_parser("server", help="Run a bcbio-nextgen server allowing remote job execution.") parser.add_argument("-c", "--config", help=("Global YAML configuration file specifying system details." ...
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Add command line arguments as server subparser.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/server/main.py#L29-L41
223,621
bcbio/bcbio-nextgen
bcbio/provenance/data.py
write_versions
def write_versions(dirs, items): """Write data versioning for genomes present in the configuration. """ genomes = {} for d in items: genomes[d["genome_build"]] = d.get("reference", {}).get("versions") out_file = _get_out_file(dirs) found_versions = False if genomes and out_file: ...
python
def write_versions(dirs, items): """Write data versioning for genomes present in the configuration. """ genomes = {} for d in items: genomes[d["genome_build"]] = d.get("reference", {}).get("versions") out_file = _get_out_file(dirs) found_versions = False if genomes and out_file: ...
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Write data versioning for genomes present in the configuration.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/provenance/data.py#L8-L34
223,622
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
combine_calls
def combine_calls(*args): """Combine multiple callsets into a final set of merged calls. """ if len(args) == 3: is_cwl = False batch_id, samples, data = args caller_names, vrn_files = _organize_variants(samples, batch_id) else: is_cwl = True samples = [utils.to_si...
python
def combine_calls(*args): """Combine multiple callsets into a final set of merged calls. """ if len(args) == 3: is_cwl = False batch_id, samples, data = args caller_names, vrn_files = _organize_variants(samples, batch_id) else: is_cwl = True samples = [utils.to_si...
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Combine multiple callsets into a final set of merged calls.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L57-L110
223,623
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
combine_calls_parallel
def combine_calls_parallel(samples, run_parallel): """Combine calls using batched Ensemble approach. """ batch_groups, extras = _group_by_batches(samples, _has_ensemble) out = [] if batch_groups: processed = run_parallel("combine_calls", ((b, xs, xs[0]) for b, xs in batch_groups.items())) ...
python
def combine_calls_parallel(samples, run_parallel): """Combine calls using batched Ensemble approach. """ batch_groups, extras = _group_by_batches(samples, _has_ensemble) out = [] if batch_groups: processed = run_parallel("combine_calls", ((b, xs, xs[0]) for b, xs in batch_groups.items())) ...
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Combine calls using batched Ensemble approach.
[ "Combine", "calls", "using", "batched", "Ensemble", "approach", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L112-L123
223,624
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
_group_by_batches
def _group_by_batches(samples, check_fn): """Group calls by batches, processing families together during ensemble calling. """ batch_groups = collections.defaultdict(list) extras = [] for data in [x[0] for x in samples]: if check_fn(data): batch_groups[multi.get_batch_for_key(dat...
python
def _group_by_batches(samples, check_fn): """Group calls by batches, processing families together during ensemble calling. """ batch_groups = collections.defaultdict(list) extras = [] for data in [x[0] for x in samples]: if check_fn(data): batch_groups[multi.get_batch_for_key(dat...
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Group calls by batches, processing families together during ensemble calling.
[ "Group", "calls", "by", "batches", "processing", "families", "together", "during", "ensemble", "calling", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L133-L143
223,625
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
_organize_variants
def _organize_variants(samples, batch_id): """Retrieve variant calls for all samples, merging batched samples into single VCF. """ caller_names = [x["variantcaller"] for x in samples[0]["variants"]] calls = collections.defaultdict(list) for data in samples: for vrn in data["variants"]: ...
python
def _organize_variants(samples, batch_id): """Retrieve variant calls for all samples, merging batched samples into single VCF. """ caller_names = [x["variantcaller"] for x in samples[0]["variants"]] calls = collections.defaultdict(list) for data in samples: for vrn in data["variants"]: ...
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Retrieve variant calls for all samples, merging batched samples into single VCF.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L145-L161
223,626
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
_handle_somatic_ensemble
def _handle_somatic_ensemble(vrn_file, data): """For somatic ensemble, discard normal samples and filtered variants from vcfs. Only needed for bcbio.variation based ensemble calling. """ if tz.get_in(["metadata", "phenotype"], data, "").lower().startswith("tumor"): vrn_file_temp = vrn_file.repl...
python
def _handle_somatic_ensemble(vrn_file, data): """For somatic ensemble, discard normal samples and filtered variants from vcfs. Only needed for bcbio.variation based ensemble calling. """ if tz.get_in(["metadata", "phenotype"], data, "").lower().startswith("tumor"): vrn_file_temp = vrn_file.repl...
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For somatic ensemble, discard normal samples and filtered variants from vcfs. Only needed for bcbio.variation based ensemble calling.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L163-L174
223,627
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
_run_ensemble
def _run_ensemble(batch_id, vrn_files, config_file, base_dir, ref_file, data): """Run an ensemble call using merging and SVM-based approach in bcbio.variation """ out_vcf_file = os.path.join(base_dir, "{0}-ensemble.vcf".format(batch_id)) out_bed_file = os.path.join(base_dir, "{0}-callregions.bed".format...
python
def _run_ensemble(batch_id, vrn_files, config_file, base_dir, ref_file, data): """Run an ensemble call using merging and SVM-based approach in bcbio.variation """ out_vcf_file = os.path.join(base_dir, "{0}-ensemble.vcf".format(batch_id)) out_bed_file = os.path.join(base_dir, "{0}-callregions.bed".format...
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Run an ensemble call using merging and SVM-based approach in bcbio.variation
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L190-L208
223,628
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
_write_config_file
def _write_config_file(batch_id, caller_names, base_dir, data): """Write YAML configuration to generate an ensemble set of combined calls. """ config_dir = utils.safe_makedir(os.path.join(base_dir, "config")) config_file = os.path.join(config_dir, "{0}-ensemble.yaml".format(batch_id)) algorithm = da...
python
def _write_config_file(batch_id, caller_names, base_dir, data): """Write YAML configuration to generate an ensemble set of combined calls. """ config_dir = utils.safe_makedir(os.path.join(base_dir, "config")) config_file = os.path.join(config_dir, "{0}-ensemble.yaml".format(batch_id)) algorithm = da...
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Write YAML configuration to generate an ensemble set of combined calls.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L210-L224
223,629
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
_get_num_pass
def _get_num_pass(data, n): """Calculate the number of samples needed to pass ensemble calling. """ numpass = tz.get_in(["config", "algorithm", "ensemble", "numpass"], data) if numpass: return int(numpass) trusted_pct = tz.get_in(["config", "algorithm", "ensemble", "trusted_pct"], data) ...
python
def _get_num_pass(data, n): """Calculate the number of samples needed to pass ensemble calling. """ numpass = tz.get_in(["config", "algorithm", "ensemble", "numpass"], data) if numpass: return int(numpass) trusted_pct = tz.get_in(["config", "algorithm", "ensemble", "trusted_pct"], data) ...
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Calculate the number of samples needed to pass ensemble calling.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L226-L235
223,630
bcbio/bcbio-nextgen
bcbio/variation/ensemble.py
_run_ensemble_intersection
def _run_ensemble_intersection(batch_id, vrn_files, callers, base_dir, edata): """Run intersection n out of x based ensemble method using bcbio.variation.recall. """ out_vcf_file = os.path.join(base_dir, "{0}-ensemble.vcf.gz".format(batch_id)) if not utils.file_exists(out_vcf_file): num_pass = _...
python
def _run_ensemble_intersection(batch_id, vrn_files, callers, base_dir, edata): """Run intersection n out of x based ensemble method using bcbio.variation.recall. """ out_vcf_file = os.path.join(base_dir, "{0}-ensemble.vcf.gz".format(batch_id)) if not utils.file_exists(out_vcf_file): num_pass = _...
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Run intersection n out of x based ensemble method using bcbio.variation.recall.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/ensemble.py#L237-L263
223,631
bcbio/bcbio-nextgen
bcbio/variation/joint.py
_get_callable_regions
def _get_callable_regions(data): """Retrieve regions to parallelize by from callable regions or chromosomes. """ import pybedtools callable_files = data.get("callable_regions") if callable_files: assert len(callable_files) == 1 regions = [(r.chrom, int(r.start), int(r.stop)) for r in...
python
def _get_callable_regions(data): """Retrieve regions to parallelize by from callable regions or chromosomes. """ import pybedtools callable_files = data.get("callable_regions") if callable_files: assert len(callable_files) == 1 regions = [(r.chrom, int(r.start), int(r.stop)) for r in...
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Retrieve regions to parallelize by from callable regions or chromosomes.
[ "Retrieve", "regions", "to", "parallelize", "by", "from", "callable", "regions", "or", "chromosomes", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/joint.py#L75-L92
223,632
bcbio/bcbio-nextgen
bcbio/variation/joint.py
_split_by_callable_region
def _split_by_callable_region(data): """Split by callable or variant regions. We expect joint calling to be deep in numbers of samples per region, so prefer splitting aggressively by regions. """ batch = tz.get_in(("metadata", "batch"), data) jointcaller = tz.get_in(("config", "algorithm", "joi...
python
def _split_by_callable_region(data): """Split by callable or variant regions. We expect joint calling to be deep in numbers of samples per region, so prefer splitting aggressively by regions. """ batch = tz.get_in(("metadata", "batch"), data) jointcaller = tz.get_in(("config", "algorithm", "joi...
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Split by callable or variant regions. We expect joint calling to be deep in numbers of samples per region, so prefer splitting aggressively by regions.
[ "Split", "by", "callable", "or", "variant", "regions", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/joint.py#L94-L114
223,633
bcbio/bcbio-nextgen
bcbio/variation/joint.py
_is_jointcaller_compatible
def _is_jointcaller_compatible(data): """Match variant caller inputs to compatible joint callers. """ jointcaller = tz.get_in(("config", "algorithm", "jointcaller"), data) variantcaller = tz.get_in(("config", "algorithm", "variantcaller"), data) if isinstance(variantcaller, (list, tuple)) and len(va...
python
def _is_jointcaller_compatible(data): """Match variant caller inputs to compatible joint callers. """ jointcaller = tz.get_in(("config", "algorithm", "jointcaller"), data) variantcaller = tz.get_in(("config", "algorithm", "variantcaller"), data) if isinstance(variantcaller, (list, tuple)) and len(va...
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Match variant caller inputs to compatible joint callers.
[ "Match", "variant", "caller", "inputs", "to", "compatible", "joint", "callers", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/joint.py#L116-L123
223,634
bcbio/bcbio-nextgen
bcbio/variation/joint.py
square_off
def square_off(samples, run_parallel): """Perform joint calling at all variants within a batch. """ to_process = [] extras = [] for data in [utils.to_single_data(x) for x in samples]: added = False if tz.get_in(("metadata", "batch"), data): for add in genotype.handle_mult...
python
def square_off(samples, run_parallel): """Perform joint calling at all variants within a batch. """ to_process = [] extras = [] for data in [utils.to_single_data(x) for x in samples]: added = False if tz.get_in(("metadata", "batch"), data): for add in genotype.handle_mult...
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Perform joint calling at all variants within a batch.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/joint.py#L125-L143
223,635
bcbio/bcbio-nextgen
bcbio/variation/joint.py
_combine_to_jointcaller
def _combine_to_jointcaller(processed): """Add joint calling information to variants, while collapsing independent regions. """ by_vrn_file = collections.OrderedDict() for data in (x[0] for x in processed): key = (tz.get_in(("config", "algorithm", "jointcaller"), data), data["vrn_file"]) ...
python
def _combine_to_jointcaller(processed): """Add joint calling information to variants, while collapsing independent regions. """ by_vrn_file = collections.OrderedDict() for data in (x[0] for x in processed): key = (tz.get_in(("config", "algorithm", "jointcaller"), data), data["vrn_file"]) ...
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Add joint calling information to variants, while collapsing independent regions.
[ "Add", "joint", "calling", "information", "to", "variants", "while", "collapsing", "independent", "regions", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/joint.py#L145-L158
223,636
bcbio/bcbio-nextgen
bcbio/variation/joint.py
square_batch_region
def square_batch_region(data, region, bam_files, vrn_files, out_file): """Perform squaring of a batch in a supplied region, with input BAMs """ from bcbio.variation import sentieon, strelka2 if not utils.file_exists(out_file): jointcaller = tz.get_in(("config", "algorithm", "jointcaller"), data)...
python
def square_batch_region(data, region, bam_files, vrn_files, out_file): """Perform squaring of a batch in a supplied region, with input BAMs """ from bcbio.variation import sentieon, strelka2 if not utils.file_exists(out_file): jointcaller = tz.get_in(("config", "algorithm", "jointcaller"), data)...
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Perform squaring of a batch in a supplied region, with input BAMs
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/joint.py#L172-L194
223,637
bcbio/bcbio-nextgen
bcbio/variation/joint.py
_fix_orig_vcf_refs
def _fix_orig_vcf_refs(data): """Supply references to initial variantcalls if run in addition to batching. """ variantcaller = tz.get_in(("config", "algorithm", "variantcaller"), data) if variantcaller: data["vrn_file_orig"] = data["vrn_file"] for i, sub in enumerate(data.get("group_orig", [...
python
def _fix_orig_vcf_refs(data): """Supply references to initial variantcalls if run in addition to batching. """ variantcaller = tz.get_in(("config", "algorithm", "variantcaller"), data) if variantcaller: data["vrn_file_orig"] = data["vrn_file"] for i, sub in enumerate(data.get("group_orig", [...
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Supply references to initial variantcalls if run in addition to batching.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/joint.py#L196-L207
223,638
bcbio/bcbio-nextgen
bcbio/variation/joint.py
_square_batch_bcbio_variation
def _square_batch_bcbio_variation(data, region, bam_files, vrn_files, out_file, todo="square"): """Run squaring or merging analysis using bcbio.variation.recall. """ ref_file = tz.get_in(("reference", "fasta", "base"), data) cores = tz.get_in(("config", "algorithm", "nu...
python
def _square_batch_bcbio_variation(data, region, bam_files, vrn_files, out_file, todo="square"): """Run squaring or merging analysis using bcbio.variation.recall. """ ref_file = tz.get_in(("reference", "fasta", "base"), data) cores = tz.get_in(("config", "algorithm", "nu...
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Run squaring or merging analysis using bcbio.variation.recall.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/joint.py#L209-L236
223,639
bcbio/bcbio-nextgen
bcbio/structural/seq2c.py
run
def run(items): """Normalization and log2 ratio calculation plus CNV calling for full cohort. - Combine coverage of each region for each sample - Prepare read counts for each sample - Normalize coverages in cohort by gene and sample, and calculate log2 ratios - Call amplifications and deletions ...
python
def run(items): """Normalization and log2 ratio calculation plus CNV calling for full cohort. - Combine coverage of each region for each sample - Prepare read counts for each sample - Normalize coverages in cohort by gene and sample, and calculate log2 ratios - Call amplifications and deletions ...
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Normalization and log2 ratio calculation plus CNV calling for full cohort. - Combine coverage of each region for each sample - Prepare read counts for each sample - Normalize coverages in cohort by gene and sample, and calculate log2 ratios - Call amplifications and deletions
[ "Normalization", "and", "log2", "ratio", "calculation", "plus", "CNV", "calling", "for", "full", "cohort", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/seq2c.py#L41-L65
223,640
bcbio/bcbio-nextgen
bcbio/structural/seq2c.py
prep_seq2c_bed
def prep_seq2c_bed(data): """Selecting the bed file, cleaning, and properly annotating for Seq2C """ if dd.get_background_cnv_reference(data, "seq2c"): bed_file = _background_to_bed(dd.get_background_cnv_reference(data, "seq2c"), data) else: bed_file = regions.get_sv_bed(data) if bed...
python
def prep_seq2c_bed(data): """Selecting the bed file, cleaning, and properly annotating for Seq2C """ if dd.get_background_cnv_reference(data, "seq2c"): bed_file = _background_to_bed(dd.get_background_cnv_reference(data, "seq2c"), data) else: bed_file = regions.get_sv_bed(data) if bed...
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Selecting the bed file, cleaning, and properly annotating for Seq2C
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/seq2c.py#L67-L102
223,641
bcbio/bcbio-nextgen
bcbio/structural/seq2c.py
_background_to_bed
def _background_to_bed(back_file, data): """Convert a seq2c background file with calls into BED regions for coverage. seq2c background files are a concatenation of mapping and sample_coverages from potentially multiple samples. We use the coverage information from the first sample to translate into BED...
python
def _background_to_bed(back_file, data): """Convert a seq2c background file with calls into BED regions for coverage. seq2c background files are a concatenation of mapping and sample_coverages from potentially multiple samples. We use the coverage information from the first sample to translate into BED...
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Convert a seq2c background file with calls into BED regions for coverage. seq2c background files are a concatenation of mapping and sample_coverages from potentially multiple samples. We use the coverage information from the first sample to translate into BED.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/seq2c.py#L104-L122
223,642
bcbio/bcbio-nextgen
bcbio/structural/seq2c.py
_get_seq2c_options
def _get_seq2c_options(data): """Get adjustable, through resources, or default options for seq2c. """ cov2lr_possible_opts = ["-F"] defaults = {} ropts = config_utils.get_resources("seq2c", data["config"]).get("options", []) assert len(ropts) % 2 == 0, "Expect even number of options for seq2c" %...
python
def _get_seq2c_options(data): """Get adjustable, through resources, or default options for seq2c. """ cov2lr_possible_opts = ["-F"] defaults = {} ropts = config_utils.get_resources("seq2c", data["config"]).get("options", []) assert len(ropts) % 2 == 0, "Expect even number of options for seq2c" %...
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Get adjustable, through resources, or default options for seq2c.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/seq2c.py#L124-L138
223,643
bcbio/bcbio-nextgen
bcbio/structural/seq2c.py
to_vcf
def to_vcf(in_tsv, data): """Convert seq2c output file into BED output. """ call_convert = {"Amp": "DUP", "Del": "DEL"} out_file = "%s.vcf" % utils.splitext_plus(in_tsv)[0] if not utils.file_uptodate(out_file, in_tsv): with file_transaction(data, out_file) as tx_out_file: with op...
python
def to_vcf(in_tsv, data): """Convert seq2c output file into BED output. """ call_convert = {"Amp": "DUP", "Del": "DEL"} out_file = "%s.vcf" % utils.splitext_plus(in_tsv)[0] if not utils.file_uptodate(out_file, in_tsv): with file_transaction(data, out_file) as tx_out_file: with op...
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Convert seq2c output file into BED output.
[ "Convert", "seq2c", "output", "file", "into", "BED", "output", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/seq2c.py#L198-L218
223,644
bcbio/bcbio-nextgen
bcbio/structural/seq2c.py
_combine_coverages
def _combine_coverages(items, work_dir, input_backs=None): """Combine coverage cnns calculated for individual inputs into single file. Optionally moves over pre-calculated coverage samples from a background file. """ out_file = os.path.join(work_dir, "sample_coverages.txt") if not utils.file_exists...
python
def _combine_coverages(items, work_dir, input_backs=None): """Combine coverage cnns calculated for individual inputs into single file. Optionally moves over pre-calculated coverage samples from a background file. """ out_file = os.path.join(work_dir, "sample_coverages.txt") if not utils.file_exists...
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Combine coverage cnns calculated for individual inputs into single file. Optionally moves over pre-calculated coverage samples from a background file.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/seq2c.py#L290-L309
223,645
bcbio/bcbio-nextgen
bcbio/structural/seq2c.py
_calculate_mapping_reads
def _calculate_mapping_reads(items, work_dir, input_backs=None): """Calculate read counts from samtools idxstats for each sample. Optionally moves over pre-calculated mapping counts from a background file. """ out_file = os.path.join(work_dir, "mapping_reads.txt") if not utils.file_exists(out_file)...
python
def _calculate_mapping_reads(items, work_dir, input_backs=None): """Calculate read counts from samtools idxstats for each sample. Optionally moves over pre-calculated mapping counts from a background file. """ out_file = os.path.join(work_dir, "mapping_reads.txt") if not utils.file_exists(out_file)...
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Calculate read counts from samtools idxstats for each sample. Optionally moves over pre-calculated mapping counts from a background file.
[ "Calculate", "read", "counts", "from", "samtools", "idxstats", "for", "each", "sample", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/seq2c.py#L311-L335
223,646
bcbio/bcbio-nextgen
bcbio/pipeline/genome.py
get_resources
def get_resources(genome, ref_file, data): """Retrieve genome information from a genome-references.yaml file. """ base_dir = os.path.normpath(os.path.dirname(ref_file)) resource_file = os.path.join(base_dir, "%s-resources.yaml" % genome.replace("-test", "")) if not os.path.exists(resource_file): ...
python
def get_resources(genome, ref_file, data): """Retrieve genome information from a genome-references.yaml file. """ base_dir = os.path.normpath(os.path.dirname(ref_file)) resource_file = os.path.join(base_dir, "%s-resources.yaml" % genome.replace("-test", "")) if not os.path.exists(resource_file): ...
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Retrieve genome information from a genome-references.yaml file.
[ "Retrieve", "genome", "information", "from", "a", "genome", "-", "references", ".", "yaml", "file", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/pipeline/genome.py#L24-L42
223,647
bcbio/bcbio-nextgen
bcbio/pipeline/genome.py
add_required_resources
def add_required_resources(resources): """Add default or empty values for required resources referenced in CWL """ required = [["variation", "cosmic"], ["variation", "clinvar"], ["variation", "dbsnp"], ["variation", "lcr"], ["variation", "polyx"], ["variation", "encode_blackl...
python
def add_required_resources(resources): """Add default or empty values for required resources referenced in CWL """ required = [["variation", "cosmic"], ["variation", "clinvar"], ["variation", "dbsnp"], ["variation", "lcr"], ["variation", "polyx"], ["variation", "encode_blackl...
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Add default or empty values for required resources referenced in CWL
[ "Add", "default", "or", "empty", "values", "for", "required", "resources", "referenced", "in", "CWL" ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/pipeline/genome.py#L44-L58
223,648
bcbio/bcbio-nextgen
bcbio/pipeline/genome.py
ensure_annotations
def ensure_annotations(resources, data): """Prepare any potentially missing annotations for downstream processing in a local directory. """ transcript_gff = tz.get_in(["rnaseq", "transcripts"], resources) if transcript_gff and utils.file_exists(transcript_gff): out_dir = os.path.join(tz.get_in([...
python
def ensure_annotations(resources, data): """Prepare any potentially missing annotations for downstream processing in a local directory. """ transcript_gff = tz.get_in(["rnaseq", "transcripts"], resources) if transcript_gff and utils.file_exists(transcript_gff): out_dir = os.path.join(tz.get_in([...
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Prepare any potentially missing annotations for downstream processing in a local directory.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/pipeline/genome.py#L60-L68
223,649
bcbio/bcbio-nextgen
bcbio/pipeline/genome.py
abs_file_paths
def abs_file_paths(xs, base_dir=None, ignore_keys=None, fileonly_keys=None, cur_key=None, do_download=True): """Normalize any file paths found in a subdirectory of configuration input. base_dir -- directory to normalize relative paths to ignore_keys -- algorithm key names to ignore norma...
python
def abs_file_paths(xs, base_dir=None, ignore_keys=None, fileonly_keys=None, cur_key=None, do_download=True): """Normalize any file paths found in a subdirectory of configuration input. base_dir -- directory to normalize relative paths to ignore_keys -- algorithm key names to ignore norma...
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Normalize any file paths found in a subdirectory of configuration input. base_dir -- directory to normalize relative paths to ignore_keys -- algorithm key names to ignore normalize for (keywords, not files/directories) fileonly_keys -- algorithm key names to only expand files (not directories) cur_key ...
[ "Normalize", "any", "file", "paths", "found", "in", "a", "subdirectory", "of", "configuration", "input", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/pipeline/genome.py#L72-L113
223,650
bcbio/bcbio-nextgen
bcbio/pipeline/genome.py
_get_galaxy_tool_info
def _get_galaxy_tool_info(galaxy_base): """Retrieve Galaxy tool-data information from defaults or galaxy config file. """ ini_file = os.path.join(galaxy_base, "universe_wsgi.ini") info = {"tool_data_table_config_path": os.path.join(galaxy_base, "tool_data_table_conf.xml"), "tool_data_path": ...
python
def _get_galaxy_tool_info(galaxy_base): """Retrieve Galaxy tool-data information from defaults or galaxy config file. """ ini_file = os.path.join(galaxy_base, "universe_wsgi.ini") info = {"tool_data_table_config_path": os.path.join(galaxy_base, "tool_data_table_conf.xml"), "tool_data_path": ...
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Retrieve Galaxy tool-data information from defaults or galaxy config file.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/pipeline/genome.py#L195-L207
223,651
bcbio/bcbio-nextgen
bcbio/pipeline/genome.py
get_builds
def get_builds(galaxy_base): """Retrieve configured genome builds and reference files, using Galaxy configuration files. Allows multiple dbkey specifications in the same file, using the most recently added. """ name = "samtools" galaxy_config = _get_galaxy_tool_info(galaxy_base) galaxy_dt = _ge...
python
def get_builds(galaxy_base): """Retrieve configured genome builds and reference files, using Galaxy configuration files. Allows multiple dbkey specifications in the same file, using the most recently added. """ name = "samtools" galaxy_config = _get_galaxy_tool_info(galaxy_base) galaxy_dt = _ge...
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Retrieve configured genome builds and reference files, using Galaxy configuration files. Allows multiple dbkey specifications in the same file, using the most recently added.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/pipeline/genome.py#L268-L285
223,652
bcbio/bcbio-nextgen
bcbio/variation/varscan.py
_get_jvm_opts
def _get_jvm_opts(config, tmp_dir): """Retrieve common options for running VarScan. Handles jvm_opts, setting user and country to English to avoid issues with different locales producing non-compliant VCF. """ resources = config_utils.get_resources("varscan", config) jvm_opts = resources.get("jv...
python
def _get_jvm_opts(config, tmp_dir): """Retrieve common options for running VarScan. Handles jvm_opts, setting user and country to English to avoid issues with different locales producing non-compliant VCF. """ resources = config_utils.get_resources("varscan", config) jvm_opts = resources.get("jv...
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Retrieve common options for running VarScan. Handles jvm_opts, setting user and country to English to avoid issues with different locales producing non-compliant VCF.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/varscan.py#L36-L48
223,653
bcbio/bcbio-nextgen
bcbio/variation/varscan.py
_varscan_options_from_config
def _varscan_options_from_config(config): """Retrieve additional options for VarScan from the configuration. """ opts = ["--min-coverage 5", "--p-value 0.98", "--strand-filter 1"] resources = config_utils.get_resources("varscan", config) if resources.get("options"): opts += [str(x) for x in ...
python
def _varscan_options_from_config(config): """Retrieve additional options for VarScan from the configuration. """ opts = ["--min-coverage 5", "--p-value 0.98", "--strand-filter 1"] resources = config_utils.get_resources("varscan", config) if resources.get("options"): opts += [str(x) for x in ...
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Retrieve additional options for VarScan from the configuration.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/varscan.py#L51-L58
223,654
bcbio/bcbio-nextgen
bcbio/variation/varscan.py
spv_freq_filter
def spv_freq_filter(line, tumor_index): """Filter VarScan calls based on the SPV value and frequency. Removes calls with SPV < 0.05 and a tumor FREQ > 0.35. False positives dominate these higher frequency, low SPV calls. They appear to be primarily non-somatic/germline variants not removed by other fi...
python
def spv_freq_filter(line, tumor_index): """Filter VarScan calls based on the SPV value and frequency. Removes calls with SPV < 0.05 and a tumor FREQ > 0.35. False positives dominate these higher frequency, low SPV calls. They appear to be primarily non-somatic/germline variants not removed by other fi...
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Filter VarScan calls based on the SPV value and frequency. Removes calls with SPV < 0.05 and a tumor FREQ > 0.35. False positives dominate these higher frequency, low SPV calls. They appear to be primarily non-somatic/germline variants not removed by other filters.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/varscan.py#L61-L91
223,655
bcbio/bcbio-nextgen
bcbio/variation/varscan.py
_create_sample_list
def _create_sample_list(in_bams, vcf_file): """Pull sample names from input BAMs and create input sample list. """ out_file = "%s-sample_list.txt" % os.path.splitext(vcf_file)[0] with open(out_file, "w") as out_handle: for in_bam in in_bams: with pysam.Samfile(in_bam, "rb") as work_b...
python
def _create_sample_list(in_bams, vcf_file): """Pull sample names from input BAMs and create input sample list. """ out_file = "%s-sample_list.txt" % os.path.splitext(vcf_file)[0] with open(out_file, "w") as out_handle: for in_bam in in_bams: with pysam.Samfile(in_bam, "rb") as work_b...
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Pull sample names from input BAMs and create input sample list.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/varscan.py#L274-L283
223,656
bcbio/bcbio-nextgen
bcbio/variation/varscan.py
_varscan_work
def _varscan_work(align_bams, ref_file, items, target_regions, out_file): """Perform SNP and indel genotyping with VarScan. """ config = items[0]["config"] orig_out_file = out_file out_file = orig_out_file.replace(".vcf.gz", ".vcf") max_read_depth = "1000" sample_list = _create_sample_list...
python
def _varscan_work(align_bams, ref_file, items, target_regions, out_file): """Perform SNP and indel genotyping with VarScan. """ config = items[0]["config"] orig_out_file = out_file out_file = orig_out_file.replace(".vcf.gz", ".vcf") max_read_depth = "1000" sample_list = _create_sample_list...
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Perform SNP and indel genotyping with VarScan.
[ "Perform", "SNP", "and", "indel", "genotyping", "with", "VarScan", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/variation/varscan.py#L286-L327
223,657
bcbio/bcbio-nextgen
bcbio/distributed/ipythontasks.py
apply
def apply(object, args=None, kwargs=None): """Python3 apply replacement for double unpacking of inputs during apply. Thanks to: https://github.com/stefanholek/apply """ if args is None: args = () if kwargs is None: kwargs = {} return object(*args, **kwargs)
python
def apply(object, args=None, kwargs=None): """Python3 apply replacement for double unpacking of inputs during apply. Thanks to: https://github.com/stefanholek/apply """ if args is None: args = () if kwargs is None: kwargs = {} return object(*args, **kwargs)
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Python3 apply replacement for double unpacking of inputs during apply. Thanks to: https://github.com/stefanholek/apply
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/ipythontasks.py#L71-L80
223,658
bcbio/bcbio-nextgen
bcbio/structural/annotate.py
add_genes
def add_genes(in_file, data, max_distance=10000, work_dir=None): """Add gene annotations to a BED file from pre-prepared RNA-seq data. max_distance -- only keep annotations within this distance of event """ gene_file = regions.get_sv_bed(data, "exons", out_dir=os.path.dirname(in_file)) if gene_file...
python
def add_genes(in_file, data, max_distance=10000, work_dir=None): """Add gene annotations to a BED file from pre-prepared RNA-seq data. max_distance -- only keep annotations within this distance of event """ gene_file = regions.get_sv_bed(data, "exons", out_dir=os.path.dirname(in_file)) if gene_file...
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Add gene annotations to a BED file from pre-prepared RNA-seq data. max_distance -- only keep annotations within this distance of event
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/annotate.py#L17-L33
223,659
bcbio/bcbio-nextgen
bcbio/structural/annotate.py
_add_genes_to_bed
def _add_genes_to_bed(in_file, gene_file, fai_file, out_file, data, max_distance=10000): """Re-usable subcomponent that annotates BED file genes from another BED """ try: input_rec = next(iter(pybedtools.BedTool(in_file))) except StopIteration: # empty file utils.copy_plus(in_file, out_...
python
def _add_genes_to_bed(in_file, gene_file, fai_file, out_file, data, max_distance=10000): """Re-usable subcomponent that annotates BED file genes from another BED """ try: input_rec = next(iter(pybedtools.BedTool(in_file))) except StopIteration: # empty file utils.copy_plus(in_file, out_...
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Re-usable subcomponent that annotates BED file genes from another BED
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/annotate.py#L35-L72
223,660
bcbio/bcbio-nextgen
bcbio/distributed/clusterk.py
create
def create(parallel): """Create a queue based on the provided parallel arguments. TODO Startup/tear-down. Currently using default queue for testing """ queue = {k: v for k, v in parallel.items() if k in ["queue", "cores_per_job", "mem"]} yield queue
python
def create(parallel): """Create a queue based on the provided parallel arguments. TODO Startup/tear-down. Currently using default queue for testing """ queue = {k: v for k, v in parallel.items() if k in ["queue", "cores_per_job", "mem"]} yield queue
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Create a queue based on the provided parallel arguments. TODO Startup/tear-down. Currently using default queue for testing
[ "Create", "a", "queue", "based", "on", "the", "provided", "parallel", "arguments", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/clusterk.py#L11-L17
223,661
bcbio/bcbio-nextgen
bcbio/distributed/clusterk.py
runner
def runner(queue, parallel): """Run individual jobs on an existing queue. """ def run(fn_name, items): logger.info("clusterk: %s" % fn_name) assert "wrapper" in parallel, "Clusterk requires bcbio-nextgen-vm wrapper" fn = getattr(__import__("{base}.clusterktasks".format(base=parallel[...
python
def runner(queue, parallel): """Run individual jobs on an existing queue. """ def run(fn_name, items): logger.info("clusterk: %s" % fn_name) assert "wrapper" in parallel, "Clusterk requires bcbio-nextgen-vm wrapper" fn = getattr(__import__("{base}.clusterktasks".format(base=parallel[...
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Run individual jobs on an existing queue.
[ "Run", "individual", "jobs", "on", "an", "existing", "queue", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/distributed/clusterk.py#L19-L34
223,662
bcbio/bcbio-nextgen
bcbio/structural/prioritize.py
is_gene_list
def is_gene_list(bed_file): """Check if the file is only a list of genes, not a BED """ with utils.open_gzipsafe(bed_file) as in_handle: for line in in_handle: if not line.startswith("#"): if len(line.split()) == 1: return True else: ...
python
def is_gene_list(bed_file): """Check if the file is only a list of genes, not a BED """ with utils.open_gzipsafe(bed_file) as in_handle: for line in in_handle: if not line.startswith("#"): if len(line.split()) == 1: return True else: ...
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Check if the file is only a list of genes, not a BED
[ "Check", "if", "the", "file", "is", "only", "a", "list", "of", "genes", "not", "a", "BED" ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/prioritize.py#L51-L60
223,663
bcbio/bcbio-nextgen
bcbio/structural/prioritize.py
_find_gene_list_from_bed
def _find_gene_list_from_bed(bed_file, base_file, data): """Retrieve list of gene names from input BED file. """ # Check for a gene list, we can just return that. if is_gene_list(bed_file): return bed_file out_file = "%s-genes.txt" % utils.splitext_plus(base_file)[0] if not os.path.exist...
python
def _find_gene_list_from_bed(bed_file, base_file, data): """Retrieve list of gene names from input BED file. """ # Check for a gene list, we can just return that. if is_gene_list(bed_file): return bed_file out_file = "%s-genes.txt" % utils.splitext_plus(base_file)[0] if not os.path.exist...
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Retrieve list of gene names from input BED file.
[ "Retrieve", "list", "of", "gene", "names", "from", "input", "BED", "file", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/prioritize.py#L62-L82
223,664
bcbio/bcbio-nextgen
bcbio/structural/prioritize.py
_combine_files
def _combine_files(tsv_files, work_dir, data): """Combine multiple priority tsv files into a final sorted output. """ header = "\t".join(["caller", "sample", "chrom", "start", "end", "svtype", "lof", "annotation", "split_read_support", "paired_support_PE", "paired_support_PR"]) s...
python
def _combine_files(tsv_files, work_dir, data): """Combine multiple priority tsv files into a final sorted output. """ header = "\t".join(["caller", "sample", "chrom", "start", "end", "svtype", "lof", "annotation", "split_read_support", "paired_support_PE", "paired_support_PR"]) s...
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Combine multiple priority tsv files into a final sorted output.
[ "Combine", "multiple", "priority", "tsv", "files", "into", "a", "final", "sorted", "output", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/prioritize.py#L145-L159
223,665
bcbio/bcbio-nextgen
bcbio/structural/prioritize.py
_cnvkit_prioritize
def _cnvkit_prioritize(sample, genes, allele_file, metrics_file): """Summarize non-diploid calls with copy numbers and confidence intervals. """ mdf = pd.read_table(metrics_file) mdf.columns = [x.lower() for x in mdf.columns] if len(genes) > 0: mdf = mdf[mdf["gene"].str.contains("|".join(gen...
python
def _cnvkit_prioritize(sample, genes, allele_file, metrics_file): """Summarize non-diploid calls with copy numbers and confidence intervals. """ mdf = pd.read_table(metrics_file) mdf.columns = [x.lower() for x in mdf.columns] if len(genes) > 0: mdf = mdf[mdf["gene"].str.contains("|".join(gen...
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Summarize non-diploid calls with copy numbers and confidence intervals.
[ "Summarize", "non", "-", "diploid", "calls", "with", "copy", "numbers", "and", "confidence", "intervals", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/prioritize.py#L167-L190
223,666
bcbio/bcbio-nextgen
bcbio/structural/prioritize.py
_cnv_prioritize
def _cnv_prioritize(data): """Perform confidence interval based prioritization for CNVs. """ supported = {"cnvkit": {"inputs": ["call_file", "segmetrics"], "fn": _cnvkit_prioritize}} pcall = None priority_files = None for call in data.get("sv", []): if call["variantcaller"] in supported:...
python
def _cnv_prioritize(data): """Perform confidence interval based prioritization for CNVs. """ supported = {"cnvkit": {"inputs": ["call_file", "segmetrics"], "fn": _cnvkit_prioritize}} pcall = None priority_files = None for call in data.get("sv", []): if call["variantcaller"] in supported:...
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Perform confidence interval based prioritization for CNVs.
[ "Perform", "confidence", "interval", "based", "prioritization", "for", "CNVs", "." ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/structural/prioritize.py#L192-L217
223,667
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
get_default_jvm_opts
def get_default_jvm_opts(tmp_dir=None, parallel_gc=False): """Retrieve default JVM tuning options Avoids issues with multiple spun up Java processes running into out of memory errors. Parallel GC can use a lot of cores on big machines and primarily helps reduce task latency and responsiveness which are...
python
def get_default_jvm_opts(tmp_dir=None, parallel_gc=False): """Retrieve default JVM tuning options Avoids issues with multiple spun up Java processes running into out of memory errors. Parallel GC can use a lot of cores on big machines and primarily helps reduce task latency and responsiveness which are...
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Retrieve default JVM tuning options Avoids issues with multiple spun up Java processes running into out of memory errors. Parallel GC can use a lot of cores on big machines and primarily helps reduce task latency and responsiveness which are not needed for batch jobs. https://github.com/bcbio/bcbio-nex...
[ "Retrieve", "default", "JVM", "tuning", "options" ]
6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L23-L38
223,668
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
_get_gatk_opts
def _get_gatk_opts(config, names, tmp_dir=None, memscale=None, include_gatk=True, parallel_gc=False): """Retrieve GATK memory specifications, moving down a list of potential specifications. """ if include_gatk and "gatk4" in dd.get_tools_off({"config": config}): opts = ["-U", "LENIENT_VCF_PROCESSING...
python
def _get_gatk_opts(config, names, tmp_dir=None, memscale=None, include_gatk=True, parallel_gc=False): """Retrieve GATK memory specifications, moving down a list of potential specifications. """ if include_gatk and "gatk4" in dd.get_tools_off({"config": config}): opts = ["-U", "LENIENT_VCF_PROCESSING...
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Retrieve GATK memory specifications, moving down a list of potential specifications.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L40-L57
223,669
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
_clean_java_out
def _clean_java_out(version_str): """Remove extra environmental information reported in java when querying for versions. Java will report information like _JAVA_OPTIONS environmental variables in the output. """ out = [] for line in version_str.decode().split("\n"): if line.startswith("Pick...
python
def _clean_java_out(version_str): """Remove extra environmental information reported in java when querying for versions. Java will report information like _JAVA_OPTIONS environmental variables in the output. """ out = [] for line in version_str.decode().split("\n"): if line.startswith("Pick...
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Remove extra environmental information reported in java when querying for versions. Java will report information like _JAVA_OPTIONS environmental variables in the output.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L69-L82
223,670
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
get_mutect_version
def get_mutect_version(mutect_jar): """Retrieves version from input jar name since there is not an easy way to get MuTect version. Check mutect jar for SomaticIndelDetector, which is an Appistry feature """ cl = ["java", "-Xms128m", "-Xmx256m"] + get_default_jvm_opts() + ["-jar", mutect_jar, "-h"] w...
python
def get_mutect_version(mutect_jar): """Retrieves version from input jar name since there is not an easy way to get MuTect version. Check mutect jar for SomaticIndelDetector, which is an Appistry feature """ cl = ["java", "-Xms128m", "-Xmx256m"] + get_default_jvm_opts() + ["-jar", mutect_jar, "-h"] w...
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Retrieves version from input jar name since there is not an easy way to get MuTect version. Check mutect jar for SomaticIndelDetector, which is an Appistry feature
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L110-L129
223,671
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
gatk_cmd
def gatk_cmd(name, jvm_opts, params, config=None): """Retrieve PATH to gatk using locally installed java. """ if name == "gatk": if isinstance(config, dict) and "config" not in config: data = {"config": config} else: data = config if not data or "gatk4" not in...
python
def gatk_cmd(name, jvm_opts, params, config=None): """Retrieve PATH to gatk using locally installed java. """ if name == "gatk": if isinstance(config, dict) and "config" not in config: data = {"config": config} else: data = config if not data or "gatk4" not in...
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Retrieve PATH to gatk using locally installed java.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L530-L549
223,672
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
_gatk4_cmd
def _gatk4_cmd(jvm_opts, params, data): """Retrieve unified command for GATK4, using 'gatk'. GATK3 is 'gatk3'. """ gatk_cmd = utils.which(os.path.join(os.path.dirname(os.path.realpath(sys.executable)), "gatk")) return "%s && export PATH=%s:\"$PATH\" && gatk --java-options '%s' %s" % \ (utils.cle...
python
def _gatk4_cmd(jvm_opts, params, data): """Retrieve unified command for GATK4, using 'gatk'. GATK3 is 'gatk3'. """ gatk_cmd = utils.which(os.path.join(os.path.dirname(os.path.realpath(sys.executable)), "gatk")) return "%s && export PATH=%s:\"$PATH\" && gatk --java-options '%s' %s" % \ (utils.cle...
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Retrieve unified command for GATK4, using 'gatk'. GATK3 is 'gatk3'.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L551-L557
223,673
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
runner_from_path
def runner_from_path(cmd, config): """Simple command line runner that expects a bash cmd in the PATH. This makes Picard tools back compatible with new approach of a single jar + bash script. """ if cmd.endswith("picard"): return PicardCmdRunner(cmd, config) else: raise ValueErro...
python
def runner_from_path(cmd, config): """Simple command line runner that expects a bash cmd in the PATH. This makes Picard tools back compatible with new approach of a single jar + bash script. """ if cmd.endswith("picard"): return PicardCmdRunner(cmd, config) else: raise ValueErro...
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Simple command line runner that expects a bash cmd in the PATH. This makes Picard tools back compatible with new approach of a single jar + bash script.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L587-L596
223,674
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner._set_default_versions
def _set_default_versions(self, config): """Retrieve pre-computed version information for expensive to retrieve versions. Starting up GATK takes a lot of resources so we do it once at start of analysis. """ out = [] for name in ["gatk", "gatk4", "picard", "mutect"]: v...
python
def _set_default_versions(self, config): """Retrieve pre-computed version information for expensive to retrieve versions. Starting up GATK takes a lot of resources so we do it once at start of analysis. """ out = [] for name in ["gatk", "gatk4", "picard", "mutect"]: v...
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Retrieve pre-computed version information for expensive to retrieve versions. Starting up GATK takes a lot of resources so we do it once at start of analysis.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L171-L184
223,675
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.new_resources
def new_resources(self, program): """Set new resource usage for the given program. This allows customization of memory usage for particular sub-programs of GATK like HaplotypeCaller. """ resources = config_utils.get_resources(program, self._config) if resources.get("jvm_o...
python
def new_resources(self, program): """Set new resource usage for the given program. This allows customization of memory usage for particular sub-programs of GATK like HaplotypeCaller. """ resources = config_utils.get_resources(program, self._config) if resources.get("jvm_o...
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Set new resource usage for the given program. This allows customization of memory usage for particular sub-programs of GATK like HaplotypeCaller.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L186-L193
223,676
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.run_fn
def run_fn(self, name, *args, **kwds): """Run pre-built functionality that used Broad tools by name. See the gatkrun, picardrun module for available functions. """ fn = None to_check = [picardrun] for ns in to_check: try: fn = getattr(ns, name...
python
def run_fn(self, name, *args, **kwds): """Run pre-built functionality that used Broad tools by name. See the gatkrun, picardrun module for available functions. """ fn = None to_check = [picardrun] for ns in to_check: try: fn = getattr(ns, name...
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Run pre-built functionality that used Broad tools by name. See the gatkrun, picardrun module for available functions.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L195-L209
223,677
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.cl_picard
def cl_picard(self, command, options, memscale=None): """Prepare a Picard commandline. """ options = ["%s=%s" % (x, y) for x, y in options] options.append("VALIDATION_STRINGENCY=SILENT") return self._get_picard_cmd(command, memscale=memscale) + options
python
def cl_picard(self, command, options, memscale=None): """Prepare a Picard commandline. """ options = ["%s=%s" % (x, y) for x, y in options] options.append("VALIDATION_STRINGENCY=SILENT") return self._get_picard_cmd(command, memscale=memscale) + options
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Prepare a Picard commandline.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L211-L216
223,678
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.run
def run(self, command, options, pipe=False, get_stdout=False, memscale=None): """Run a Picard command with the provided option pairs. """ cl = self.cl_picard(command, options, memscale=memscale) if pipe: subprocess.Popen(cl) elif get_stdout: p = subprocess...
python
def run(self, command, options, pipe=False, get_stdout=False, memscale=None): """Run a Picard command with the provided option pairs. """ cl = self.cl_picard(command, options, memscale=memscale) if pipe: subprocess.Popen(cl) elif get_stdout: p = subprocess...
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Run a Picard command with the provided option pairs.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L218-L231
223,679
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.cl_mutect
def cl_mutect(self, params, tmp_dir): """Define parameters to run the mutect paired algorithm. """ gatk_jar = self._get_jar("muTect", ["mutect"]) # Decrease memory slightly from configuration to avoid memory allocation errors jvm_opts = config_utils.adjust_opts(self._jvm_opts, ...
python
def cl_mutect(self, params, tmp_dir): """Define parameters to run the mutect paired algorithm. """ gatk_jar = self._get_jar("muTect", ["mutect"]) # Decrease memory slightly from configuration to avoid memory allocation errors jvm_opts = config_utils.adjust_opts(self._jvm_opts, ...
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Define parameters to run the mutect paired algorithm.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L330-L339
223,680
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.run_gatk
def run_gatk(self, params, tmp_dir=None, log_error=True, data=None, region=None, memscale=None, parallel_gc=False, ld_preload=False): """Top level interface to running a GATK command. ld_preload injects required libraries for Java JNI calls: https://gatkforums.broadinstitute.or...
python
def run_gatk(self, params, tmp_dir=None, log_error=True, data=None, region=None, memscale=None, parallel_gc=False, ld_preload=False): """Top level interface to running a GATK command. ld_preload injects required libraries for Java JNI calls: https://gatkforums.broadinstitute.or...
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Top level interface to running a GATK command. ld_preload injects required libraries for Java JNI calls: https://gatkforums.broadinstitute.org/gatk/discussion/8810/something-about-create-pon-workflow
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L341-L365
223,681
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.get_gatk_version
def get_gatk_version(self): """Retrieve GATK version, handling locally and config cached versions. Calling version can be expensive due to all the startup and shutdown of JVMs, so we prefer cached version information. """ if self._gatk_version is None: self._set_defau...
python
def get_gatk_version(self): """Retrieve GATK version, handling locally and config cached versions. Calling version can be expensive due to all the startup and shutdown of JVMs, so we prefer cached version information. """ if self._gatk_version is None: self._set_defau...
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Retrieve GATK version, handling locally and config cached versions. Calling version can be expensive due to all the startup and shutdown of JVMs, so we prefer cached version information.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L376-L398
223,682
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.get_mutect_version
def get_mutect_version(self): """Retrieve the Mutect version. """ if self._mutect_version is None: mutect_jar = self._get_jar("muTect", ["mutect"]) self._mutect_version = get_mutect_version(mutect_jar) return self._mutect_version
python
def get_mutect_version(self): """Retrieve the Mutect version. """ if self._mutect_version is None: mutect_jar = self._get_jar("muTect", ["mutect"]) self._mutect_version = get_mutect_version(mutect_jar) return self._mutect_version
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Retrieve the Mutect version.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L400-L406
223,683
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner.gatk_major_version
def gatk_major_version(self): """Retrieve the GATK major version, handling multiple GATK distributions. Has special cases for GATK nightly builds, Appistry releases and GATK prior to 2.3. """ full_version = self.get_gatk_version() # Working with a recent version if using...
python
def gatk_major_version(self): """Retrieve the GATK major version, handling multiple GATK distributions. Has special cases for GATK nightly builds, Appistry releases and GATK prior to 2.3. """ full_version = self.get_gatk_version() # Working with a recent version if using...
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Retrieve the GATK major version, handling multiple GATK distributions. Has special cases for GATK nightly builds, Appistry releases and GATK prior to 2.3.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
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223,684
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner._get_picard_cmd
def _get_picard_cmd(self, command, memscale=None): """Retrieve the base Picard command, handling both shell scripts and directory of jars. """ resources = config_utils.get_resources("picard", self._config) if memscale: jvm_opts = get_picard_opts(self._config, memscale=memscal...
python
def _get_picard_cmd(self, command, memscale=None): """Retrieve the base Picard command, handling both shell scripts and directory of jars. """ resources = config_utils.get_resources("picard", self._config) if memscale: jvm_opts = get_picard_opts(self._config, memscale=memscal...
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Retrieve the base Picard command, handling both shell scripts and directory of jars.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L446-L461
223,685
bcbio/bcbio-nextgen
bcbio/broad/__init__.py
BroadRunner._get_jar
def _get_jar(self, command, alts=None, allow_missing=False): """Retrieve the jar for running the specified command. """ dirs = [] for bdir in [self._gatk_dir, self._picard_ref]: dirs.extend([bdir, os.path.join(bdir, os.pardir, "gatk")]) if alt...
python
def _get_jar(self, command, alts=None, allow_missing=False): """Retrieve the jar for running the specified command. """ dirs = [] for bdir in [self._gatk_dir, self._picard_ref]: dirs.extend([bdir, os.path.join(bdir, os.pardir, "gatk")]) if alt...
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Retrieve the jar for running the specified command.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/broad/__init__.py#L463-L484
223,686
bcbio/bcbio-nextgen
bcbio/utils.py
cpmap
def cpmap(cores=1): """Configurable parallel map context manager. Returns appropriate map compatible function based on configuration: - Local single core (the default) - Multiple local cores """ if int(cores) == 1: yield itertools.imap else: if futures is None: r...
python
def cpmap(cores=1): """Configurable parallel map context manager. Returns appropriate map compatible function based on configuration: - Local single core (the default) - Multiple local cores """ if int(cores) == 1: yield itertools.imap else: if futures is None: r...
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Configurable parallel map context manager. Returns appropriate map compatible function based on configuration: - Local single core (the default) - Multiple local cores
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L34-L48
223,687
bcbio/bcbio-nextgen
bcbio/utils.py
map_wrap
def map_wrap(f): """Wrap standard function to easily pass into 'map' processing. """ @functools.wraps(f) def wrapper(*args, **kwargs): return f(*args, **kwargs) return wrapper
python
def map_wrap(f): """Wrap standard function to easily pass into 'map' processing. """ @functools.wraps(f) def wrapper(*args, **kwargs): return f(*args, **kwargs) return wrapper
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Wrap standard function to easily pass into 'map' processing.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L50-L56
223,688
bcbio/bcbio-nextgen
bcbio/utils.py
unpack_worlds
def unpack_worlds(items): """Handle all the ways we can pass multiple samples for back-compatibility. """ # Unpack nested lists of samples grouped together (old IPython style) if isinstance(items[0], (list, tuple)) and len(items[0]) == 1: out = [] for d in items: assert len(d...
python
def unpack_worlds(items): """Handle all the ways we can pass multiple samples for back-compatibility. """ # Unpack nested lists of samples grouped together (old IPython style) if isinstance(items[0], (list, tuple)) and len(items[0]) == 1: out = [] for d in items: assert len(d...
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Handle all the ways we can pass multiple samples for back-compatibility.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L160-L174
223,689
bcbio/bcbio-nextgen
bcbio/utils.py
safe_makedir
def safe_makedir(dname): """Make a directory if it doesn't exist, handling concurrent race conditions. """ if not dname: return dname num_tries = 0 max_tries = 5 while not os.path.exists(dname): # we could get an error here if multiple processes are creating # the directo...
python
def safe_makedir(dname): """Make a directory if it doesn't exist, handling concurrent race conditions. """ if not dname: return dname num_tries = 0 max_tries = 5 while not os.path.exists(dname): # we could get an error here if multiple processes are creating # the directo...
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Make a directory if it doesn't exist, handling concurrent race conditions.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L176-L193
223,690
bcbio/bcbio-nextgen
bcbio/utils.py
tmpfile
def tmpfile(*args, **kwargs): """Make a tempfile, safely cleaning up file descriptors on completion. """ (fd, fname) = tempfile.mkstemp(*args, **kwargs) try: yield fname finally: os.close(fd) if os.path.exists(fname): os.remove(fname)
python
def tmpfile(*args, **kwargs): """Make a tempfile, safely cleaning up file descriptors on completion. """ (fd, fname) = tempfile.mkstemp(*args, **kwargs) try: yield fname finally: os.close(fd) if os.path.exists(fname): os.remove(fname)
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Make a tempfile, safely cleaning up file descriptors on completion.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L221-L230
223,691
bcbio/bcbio-nextgen
bcbio/utils.py
file_exists
def file_exists(fname): """Check if a file exists and is non-empty. """ try: return fname and os.path.exists(fname) and os.path.getsize(fname) > 0 except OSError: return False
python
def file_exists(fname): """Check if a file exists and is non-empty. """ try: return fname and os.path.exists(fname) and os.path.getsize(fname) > 0 except OSError: return False
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Check if a file exists and is non-empty.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L232-L238
223,692
bcbio/bcbio-nextgen
bcbio/utils.py
get_size
def get_size(path): """ Returns the size in bytes if `path` is a file, or the size of all files in `path` if it's a directory. Analogous to `du -s`. """ if os.path.isfile(path): return os.path.getsize(path) return sum(get_size(os.path.join(path, f)) for f in os.listdir(path))
python
def get_size(path): """ Returns the size in bytes if `path` is a file, or the size of all files in `path` if it's a directory. Analogous to `du -s`. """ if os.path.isfile(path): return os.path.getsize(path) return sum(get_size(os.path.join(path, f)) for f in os.listdir(path))
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Returns the size in bytes if `path` is a file, or the size of all files in `path` if it's a directory. Analogous to `du -s`.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L241-L248
223,693
bcbio/bcbio-nextgen
bcbio/utils.py
read_galaxy_amqp_config
def read_galaxy_amqp_config(galaxy_config, base_dir): """Read connection information on the RabbitMQ server from Galaxy config. """ galaxy_config = add_full_path(galaxy_config, base_dir) config = six.moves.configparser.ConfigParser() config.read(galaxy_config) amqp_config = {} for option in ...
python
def read_galaxy_amqp_config(galaxy_config, base_dir): """Read connection information on the RabbitMQ server from Galaxy config. """ galaxy_config = add_full_path(galaxy_config, base_dir) config = six.moves.configparser.ConfigParser() config.read(galaxy_config) amqp_config = {} for option in ...
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Read connection information on the RabbitMQ server from Galaxy config.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L279-L288
223,694
bcbio/bcbio-nextgen
bcbio/utils.py
move_safe
def move_safe(origin, target): """ Move file, skip if exists """ if origin == target: return origin if file_exists(target): return target shutil.move(origin, target) return target
python
def move_safe(origin, target): """ Move file, skip if exists """ if origin == target: return origin if file_exists(target): return target shutil.move(origin, target) return target
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Move file, skip if exists
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L315-L324
223,695
bcbio/bcbio-nextgen
bcbio/utils.py
file_plus_index
def file_plus_index(fname): """Convert a file name into the file plus required indexes. """ exts = {".vcf": ".idx", ".bam": ".bai", ".vcf.gz": ".tbi", ".bed.gz": ".tbi", ".fq.gz": ".gbi"} ext = splitext_plus(fname)[-1] if ext in exts: return [fname, fname + exts[ext]] else: ...
python
def file_plus_index(fname): """Convert a file name into the file plus required indexes. """ exts = {".vcf": ".idx", ".bam": ".bai", ".vcf.gz": ".tbi", ".bed.gz": ".tbi", ".fq.gz": ".gbi"} ext = splitext_plus(fname)[-1] if ext in exts: return [fname, fname + exts[ext]] else: ...
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Convert a file name into the file plus required indexes.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L326-L335
223,696
bcbio/bcbio-nextgen
bcbio/utils.py
remove_plus
def remove_plus(orig): """Remove a fils, including biological index files. """ for ext in ["", ".idx", ".gbi", ".tbi", ".bai"]: if os.path.exists(orig + ext): remove_safe(orig + ext)
python
def remove_plus(orig): """Remove a fils, including biological index files. """ for ext in ["", ".idx", ".gbi", ".tbi", ".bai"]: if os.path.exists(orig + ext): remove_safe(orig + ext)
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Remove a fils, including biological index files.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L337-L342
223,697
bcbio/bcbio-nextgen
bcbio/utils.py
copy_plus
def copy_plus(orig, new): """Copy a fils, including biological index files. """ for ext in ["", ".idx", ".gbi", ".tbi", ".bai"]: if os.path.exists(orig + ext) and (not os.path.lexists(new + ext) or not os.path.exists(new + ext)): shutil.copyfile(orig + ext, new + ext)
python
def copy_plus(orig, new): """Copy a fils, including biological index files. """ for ext in ["", ".idx", ".gbi", ".tbi", ".bai"]: if os.path.exists(orig + ext) and (not os.path.lexists(new + ext) or not os.path.exists(new + ext)): shutil.copyfile(orig + ext, new + ext)
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Copy a fils, including biological index files.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L344-L349
223,698
bcbio/bcbio-nextgen
bcbio/utils.py
merge_config_files
def merge_config_files(fnames): """Merge configuration files, preferring definitions in latter files. """ def _load_yaml(fname): with open(fname) as in_handle: config = yaml.safe_load(in_handle) return config out = _load_yaml(fnames[0]) for fname in fnames[1:]: cu...
python
def merge_config_files(fnames): """Merge configuration files, preferring definitions in latter files. """ def _load_yaml(fname): with open(fname) as in_handle: config = yaml.safe_load(in_handle) return config out = _load_yaml(fnames[0]) for fname in fnames[1:]: cu...
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Merge configuration files, preferring definitions in latter files.
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L475-L490
223,699
bcbio/bcbio-nextgen
bcbio/utils.py
deepish_copy
def deepish_copy(org): """Improved speed deep copy for dictionaries of simple python types. Thanks to Gregg Lind: http://writeonly.wordpress.com/2009/05/07/deepcopy-is-a-pig-for-simple-data/ """ out = dict().fromkeys(org) for k, v in org.items(): if isinstance(v, dict): out[...
python
def deepish_copy(org): """Improved speed deep copy for dictionaries of simple python types. Thanks to Gregg Lind: http://writeonly.wordpress.com/2009/05/07/deepcopy-is-a-pig-for-simple-data/ """ out = dict().fromkeys(org) for k, v in org.items(): if isinstance(v, dict): out[...
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Improved speed deep copy for dictionaries of simple python types. Thanks to Gregg Lind: http://writeonly.wordpress.com/2009/05/07/deepcopy-is-a-pig-for-simple-data/
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6a9348c0054ccd5baffd22f1bb7d0422f6978b20
https://github.com/bcbio/bcbio-nextgen/blob/6a9348c0054ccd5baffd22f1bb7d0422f6978b20/bcbio/utils.py#L492-L510